About the Authors

Chad K Heazlewood

Contributed equally to this work with: Chad K Heazlewood, Matthew C Cook, Rajaraman Eri

Affiliation Mucin and IBD Research Teams, Mucosal Diseases Program, Mater Medical Research Institute, and the University of Queensland, Aubigny Place, Mater Health Services, South Brisbane, Queensland, Australia

Matthew C Cook

Contributed equally to this work with: Chad K Heazlewood, Matthew C Cook, Rajaraman Eri

Address ¤ Current address: Australian National University Medical School, Canberra, Australia

Affiliation Immunology and Inflammation Group, Phenomix Australia, Acton, Australia

Rajaraman Eri

Contributed equally to this work with: Chad K Heazlewood, Matthew C Cook, Rajaraman Eri

Affiliation Mucin and IBD Research Teams, Mucosal Diseases Program, Mater Medical Research Institute, and the University of Queensland, Aubigny Place, Mater Health Services, South Brisbane, Queensland, Australia

Gareth R Price

Affiliation Molecular Genetics Team, Mater Medical Research Institute, and the University of Queensland, Aubigny Place, Mater Health Services, South Brisbane, Queensland, Australia

Sharyn B Tauro

Affiliation Mucin and IBD Research Teams, Mucosal Diseases Program, Mater Medical Research Institute, and the University of Queensland, Aubigny Place, Mater Health Services, South Brisbane, Queensland, Australia

Douglas Taupin

Affiliation Gastroenterology Unit, Canberra Hospital, Woden, Australia

David J Thornton

Affiliation Wellcome Trust Centre for Cell Matrix Research, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom

Chin Wen Png

Affiliation Mucin and IBD Research Teams, Mucosal Diseases Program, Mater Medical Research Institute, and the University of Queensland, Aubigny Place, Mater Health Services, South Brisbane, Queensland, Australia

Tanya L Crockford

Affiliation Nuffield Dept of Clinical Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom

Richard J Cornall

Affiliation Nuffield Dept of Clinical Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom

Rachel Adams

Affiliation Mucin and IBD Research Teams, Mucosal Diseases Program, Mater Medical Research Institute, and the University of Queensland, Aubigny Place, Mater Health Services, South Brisbane, Queensland, Australia

Masato Kato

Affiliation Dendritic Cell Program, Mater Medical Research Institute, Aubigny Place, Mater Health Services, South Brisbane, Queensland, Australia

Keats A Nelms

Address ¤ Current address: Australian National University Medical School, Canberra, Australia

Affiliation Immunology and Inflammation Group, Phenomix Australia, Acton, Australia

Nancy A Hong

Affiliation Phenomix Corporation, San Diego, California, United States of America

Timothy H. J Florin

Affiliation Mucin and IBD Research Teams, Mucosal Diseases Program, Mater Medical Research Institute, and the University of Queensland, Aubigny Place, Mater Health Services, South Brisbane, Queensland, Australia

Christopher C Goodnow

Affiliation Division of Immunology and Genetics and Australian Phenomics Facility, John Curtin School of Medical Research, The Australian National University, Canberra, Australia

Michael A McGuckin

To whom correspondence should be addressed. E-mail: mmcguckin@mmri.mater.org.au

Affiliation Mucin and IBD Research Teams, Mucosal Diseases Program, Mater Medical Research Institute, and the University of Queensland, Aubigny Place, Mater Health Services, South Brisbane, Queensland, Australia

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

CKH, MCC, RE, GRP, SBT, DT, DJT, CWP, TLC, RA, MK, KAN, NAH, and MAM planned and conducted experiments, analysed data, and contributed to preparation of the manuscript. RJC, THJF, and CCG were involved in experimental planning, data analysis and preparation of the manuscript.