About the Authors

Benjamin L Ebert

Contributed equally to this work with: Benjamin L Ebert, Naomi Galili

Affiliations Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America , Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America , Brigham and Women's Hospital, Department of Medicine, Boston, Massachusetts, United States of America

Naomi Galili

Contributed equally to this work with: Benjamin L Ebert, Naomi Galili

Affiliation St. Vincent's Comprehensive Cancer Center, New York, New York, United States of America

Pablo Tamayo

Affiliation Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Jocelyn Bosco

Affiliations Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America , Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America

Raymond Mak

Affiliations Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America , Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America

Jennifer Pretz

Affiliations Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America , Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America

Shyam Tanguturi

Affiliation Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Christine Ladd-Acosta

Affiliation Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Richard Stone

Affiliations Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America , Brigham and Women's Hospital, Department of Medicine, Boston, Massachusetts, United States of America

Todd R Golub

Affiliations Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America , Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America , Childrens's Hospital, Boston, Massachusetts, United States of America , Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America

Azra Raza

To whom correspondence should be addressed. E-mail: araza@aptiumoncology.com

Affiliation St. Vincent's Comprehensive Cancer Center, New York, New York, United States of America

Competing Interests

Azra Raza and Richard Stone are involved with a speaker's bureau for Celgene.

Author Contributions

BLE designed research, analyzed data, and wrote the manuscript. NG designed research and collected data. PT analyzed data. JB, RM, JP, ST, and CL performed experiments. RS contributed vital samples. TRG supervised all aspects of the work. AR supervised all aspects of the work and contributed vital samples.