About the Authors

Shirley H. J Mei

Affiliations The Terrence Donnelly Research Laboratories, Division of Cardiology, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada , Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada

Sarah D McCarter

Affiliation The Terrence Donnelly Research Laboratories, Division of Cardiology, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada

Yupu Deng

Affiliation The Terrence Donnelly Research Laboratories, Division of Cardiology, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada

Colleen H Parker

Affiliation The Terrence Donnelly Research Laboratories, Division of Cardiology, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada

W. Conrad Liles

Affiliations Division of Infectious Diseases, McLaughlin-Rotman Centre for Global Health, Toronto General Research Institute, University of Toronto, Toronto, Ontario, Canada , Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada , Department of Medicine, University of Toronto, Toronto, Ontario, Canada , McLaughlin Centre for Molecular Medicine, University of Toronto, Toronto, Ontario, Canada

Duncan J Stewart

To whom correspondence should be addressed. E-mail: djstewartd@ohri.ca

Affiliations The Terrence Donnelly Research Laboratories, Division of Cardiology, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada , Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada , Department of Medicine, University of Toronto, Toronto, Ontario, Canada , McLaughlin Centre for Molecular Medicine, University of Toronto, Toronto, Ontario, Canada

Competing Interests

This work was supported in part by Northern Therapeutics, for which Duncan J. Stewart serves as its Chief Scientific Officer and has an equity position in the company. There are no other financial conflicts.

Author Contributions

SHJM, SDM and DJS designed the study. SHJM, WCL, and DJS analyzed the data. SHJM, YD, CHP, WCL, and DJS contributed to writing the paper. SHJM, SDM, and YD collected data and performed in vivo experiments for this study. SHJM and SDM established the model together, performed surgeries on mice in tandem, and collected all tissues together. SDM also contributed to some of the very preliminary data analysis. SHJM and CHP were involved in culturing, profiling, labeling, and transfecting the MSCs, and performed ELISAs as well as the confocal microscopy work.