About the Authors

Yan Chen, Heather C Whetstone, Alvin C Lin, Puviindran Nadesan, Qingxia Wei, Raymond Poon, Benjamin A Alman
Program in Developmental and Stem Cell Biology, the Hospital for Sick Children, University of Toronto, Toronto, Canada

Benjamin A Alman
Division of Orthopaedic Surgery, Department of Surgery, University of Toronto, Toronto, Canada

Corresponding Author


Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

YC and BAA designed the study. YC, PN, QW, RP, and BAA analyzed the data. BAA enrolled patients. YC and BAA contributed to writing the paper. YC, HCW, and ACL collected data or performed experiments for this study. ACL provided mice expressing osteoblast-specific β-catenin null alleles. PN helped in transgenic mice work. QW provided the Ad-Cre virus that was used for this study.