About the Authors

John J Aponte, Clara Menendez, David Schellenberg, Pedro L Alonso
Barcelona Centre for International Health Research, Hospital Clinic/IDIBAPS, Universitat de Barcelona, Barcelona, Spain

John J Aponte, Clara Menendez, Pedro L Alonso
Centro de Investigacão en Saude de Manhica, Manhica, Mozambique

David Schellenberg, Elizeus Kahigwa, Hassan Mshinda
Ifakara Health Research and Development Centre, Ifakara, Tanzania

Penelope Vountasou, Marcel Tanner
Swiss Tropical Institute, Basel, Switzerland

Corresponding Author


Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

JJA, CM, EK, HM, MT, and PLA designed the study. JJA, MT, and PLA analyzed the data. CM, DS, and EK enrolled patients. JJA, CM, DS, EK, HM, MT, and PLA contributed to writing the paper. EK, HM, and PLA collected data or performed experiments for this study. DS helped to coordinate the team that recruited and followed-up children in Ifakara. EK was involved in the recruitment of children for whom baseline data were collected through both clinical and laboratory tests. EK supervised the field work concerning weekly malaria chemoprophylaxis, and performed follow-up in cross-sectional surveys where physical examination of children was done and laboratory tests were taken. EK also performed follow-up in passive case detection if the child became ill and needed clinical attention. PV was involved in the study design and data management, and supported the statistical analysis. MT assisted in coordinating the whole programme of which this paper is part.