About the Authors

Geoffrey K Aguirre

To whom correspondence should be addressed. E-mail: aguirreg@mail.med.upenn.edu

Affiliation Department of Neurology, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

András M Komáromy

Affiliation Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Artur V Cideciyan

Affiliation Department of Ophthalmology, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

David H Brainard

Affiliation Department of Psychology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Tomas S Aleman

Affiliation Department of Ophthalmology, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Alejandro J Roman

Affiliation Department of Ophthalmology, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Brian B Avants

Affiliation Department of Radiology, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

James C Gee

Affiliation Department of Radiology, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Marc Korczykowski

Affiliation Department of Neurology, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

William W Hauswirth

Affiliation Department of Ophthalmology, University of Florida, Gainesville, Florida

Gregory M Acland

Affiliation Baker Institute, College of Veterinary Medicine, Cornell University, Ithaca, New York, United States of America

Gustavo D Aguirre

Affiliation Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Geoffrey K Aguirre

Affiliation Department of Ophthalmology, School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Competing Interests

WWH and the University of Florida have a financial interest in the company AGTC, which might commercialize some of the technology described in this paper. A conflict of interest monitoring plan is in place at the University of Florida.

Author Contributions

GKA, AMK, AVC, DHB, TSA, WWH, GMA, GDA, and SGJ contributed to the design of the study. GKA, AMK, AVC, TSA, AJR, MK, WWH, GMA, GDA, and SGJ collected data or performed experiments for this study. GKA, AMK, AVC, DHB, TSA, AJR, BBA, JCG, MK, WWH, GMA, GDA, and SGJ contributed to data analysis or development of methodology. SGJ enrolled patients. GKA, AMK, AVC, DHB, TSA, AJR, MK, WWH, GMA, GDA and SGJ contributed to writing the paper.