About the Authors

Ewan R Pearson

Contributed equally to this work with: Ewan R Pearson, Sylvia F Boj, Anna M Steele

Affiliations Peninsula Medical School, Exeter, United Kingdom , Division of Medicine and Therapeutics, Ninewells Hospital and Medical School, University of Dundee, Dundee, United Kingdom

Sylvia F Boj

Contributed equally to this work with: Ewan R Pearson, Sylvia F Boj, Anna M Steele

Affiliations Department of Endocrinology, Hospital Clinic de Barcelona, Barcelona, Spain , Genomic Programming of Beta Cells Laboratory, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain

Anna M Steele

Contributed equally to this work with: Ewan R Pearson, Sylvia F Boj, Anna M Steele

Affiliation Peninsula Medical School, Exeter, United Kingdom

Timothy Barrett

Affiliation Institute of Child Health, Birmingham, United Kingdom

Karen Stals

Affiliation Peninsula Medical School, Exeter, United Kingdom

Julian P Shield

Affiliations Bristol Royal Hospital for Children, Bristol, United Kingdom , University of Bristol, Bristol, United Kingdom

Sian Ellard

Affiliation Peninsula Medical School, Exeter, United Kingdom

Jorge Ferrer

Affiliations Department of Endocrinology, Hospital Clinic de Barcelona, Barcelona, Spain , Genomic Programming of Beta Cells Laboratory, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain

Andrew T Hattersley

To whom correspondence should be addressed. E-mail: A.T.Hattersley@ex.ac.uk

Affiliation Peninsula Medical School, Exeter, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

ERP, SFB, AMS, SE, JF, and ATH were involved with the study design and data analysis. The mouse studies were undertaken by SFB and JF. The human molecular genetic analysis was carried out by KS and SE. All authors were involved with interpretation of the data and preparation of the manuscript.