About the Authors
- Michael Huber
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Affiliation Division of Infectious Diseases, University Hospital Zürich, Zürich, Switzerland
- Marek Fischer
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Affiliation Division of Infectious Diseases, University Hospital Zürich, Zürich, Switzerland
- Benjamin Misselwitz
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Affiliation Division of Infectious Diseases, University Hospital Zürich, Zürich, Switzerland
- Amapola Manrique
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Affiliation Division of Infectious Diseases, University Hospital Zürich, Zürich, Switzerland
- Herbert Kuster
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Affiliation Division of Infectious Diseases, University Hospital Zürich, Zürich, Switzerland
- Barbara Niederöst
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Affiliation Division of Infectious Diseases, University Hospital Zürich, Zürich, Switzerland
- Rainer Weber
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Affiliation Division of Infectious Diseases, University Hospital Zürich, Zürich, Switzerland
- Viktor von Wyl
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Affiliation Division of Infectious Diseases, University Hospital Zürich, Zürich, Switzerland
- Huldrych F Günthard
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Affiliation Division of Infectious Diseases, University Hospital Zürich, Zürich, Switzerland
- Alexandra Trkola
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*To whom correspondence should be addressed. E-mail: alexandra.trkola@usz.ch
Affiliation Division of Infectious Diseases, University Hospital Zürich, Zürich, Switzerland
Competing Interests
The authors declare that no competing interests exist.
Author Contributions
MH, MF, HFG, and AT designed the study. MH, MF, VvW, and AT analyzed the data. RW and HFG enrolled patients. MH, MF, AM, HK, RW, VvW, HFG, and AT contributed to writing the paper. BM developed the assay for the determination of GP41 antibody titers, determined all the antibody titers (anti-gp41, anti-gp120, and anti-p24), and analyzed these data. AM provided an experimental contribution to assays. HK performed virus isolations and neutralization assays and determined plasma IgG titers. BN performed RNA extractions and real-time PCRs. RW contributed to the design of the clinical studies and collection of patients' data. HFG designed and conducted the clinical studies forming the base for this laboratory work and was significantly involved in the overall design of this investigation.