About the Authors

Ekaterina Dadachova

To whom correspondence should be addressed. E-mail: edadacho@aecom.yu.edu

Affiliation Albert Einstein College of Medicine, Bronx, New York, United States of America

Mahesh C Patel

Affiliations Albert Einstein College of Medicine, Bronx, New York, United States of America , Jacobi Medical Center, Bronx, New York, United States of America

Sima Toussi

Affiliation Albert Einstein College of Medicine, Bronx, New York, United States of America

Christos Apostolidis

Affiliation European Commission, Joint Research Centre, Institute for Transuranium Elements, Karlsruhe, Germany

Alfred Morgenstern

Affiliation European Commission, Joint Research Centre, Institute for Transuranium Elements, Karlsruhe, Germany

Martin W Brechbiel

Affiliation National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

Miroslaw K Gorny

Affiliation New York University School of Medicine, New York, New York, United States of America

Susan Zolla-Pazner

Affiliations New York University School of Medicine, New York, New York, United States of America , Veterans Affairs New York Harbor Healthcare System, New York, New York, United States of America

Arturo Casadevall

Affiliation Albert Einstein College of Medicine, Bronx, New York, United States of America

Harris Goldstein

Affiliation Albert Einstein College of Medicine, Bronx, New York, United States of America

Competing Interests

AC and ED are consultants for Pain Therapeutics on a project unrelated to the work described in the manuscript. The relationship with the company involves monetary compensation for our advice, reimbursement for company related travel, and share options. The patent application for the treatment of HIV/AIDS with RIT has been licensed by Albert Einstein College of Medicine to Pain Therapeutics.

Author Contributions

AC provided the idea for this study. ED, MCP, AC, SZP and HG designed the study. ED, MCP, ST, SZP, AC, and HG analyzed the data. ED, MCP, MWB, MKG, SZP, AC, and HG contributed to writing the paper. CA and AM supplied 225Ac/213Bi radionuclide generators. MWB synthesized and provided the bifunctional chelating agent that was used for these studies. MKG did the following experiments for the study: binding of the human monoclonal antibodies 246, 447, and 1418 to hPBMCs infected with HIV-1JR-CSF. SZP and MKG produced and provided human monoclonal antibodies 246-D, 447, and 1418.