About the Authors

Anju Singh

Affiliation Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America

Vikas Misra

Affiliation Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America

Rajesh K Thimmulappa

Affiliation Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America

Hannah Lee

Affiliation Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America

Stephen Ames

Affiliation Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, United States of America

Mohammad O Hoque

Affiliation Department of Otolaryngology—Head and Neck Surgery, Johns Hopkins University, Baltimore, Maryland, United States of America

James G Herman

Affiliation Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, United States of America

Stephen B Baylin

Affiliation Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, United States of America

David Sidransky

Affiliations Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, United States of America , Department of Otolaryngology—Head and Neck Surgery, Johns Hopkins University, Baltimore, Maryland, United States of America

Edward Gabrielson

Affiliation Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, United States of America

Malcolm V Brock

Affiliation Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, United States of America

Shyam Biswal

To whom correspondence should be addressed. E-mail: sbiswal@jhsph.edu

Affiliations Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America , Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, Maryland, United States of America , Division of Pulmonary and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

AS, SBB, and SB designed the experiments. AS, VM, RKT, HL, SA, and EG performed the experiments. AS, MOH, DS, and SB were involved in data analysis. MB was involved in collection and maintenance of all the human tissue samples. JGH provided all the cancer cell lines. SB contributed reagents/materials. AS, JGH, SBB, DS, and SB contributed to writing the paper.