About the Authors

Marcus Altfeld, Elizabeth T Kalife, Hendrik Streeck, Mathias Lichterfeld, Mary N Johnston, Nicole Burgett, Martha E Swartz, Amy Yang, Galit Alter, Xu G Yu, Angela Meier, Todd M Allen, Eric S Rosenberg, Bruce D Walker
Partners AIDS Research Center, Infectious Disease Unit, Massachusetts General Hospital and Division of AIDS, Harvard Medical School Boston, Boston, Massachusetts, United States of America

Ying Qi, Mary Carrington
Basic Research Program, SAIC-Frederick, Laboratory of Genomic Diversity, National Cancer Institute, Frederick, Maryland, United States of America

Hendrik Streeck, Heiko Jessen
Gemeinschaftspraxis Jessen, Berlin, Germany

Juergen K Rockstroh
Department of Internal Medicine, University of Bonn, Bonn, Germany

Bruce D Walker
Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America

Corresponding Author

maltfeld@partners.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

MA and BW designed the study. MA, EK, YQ, HS, ML, MES, TMA, ER, MC, and BW analyzed the data. MNJ, NB, HJ, and ER enrolled patients. MA, HS, JR, HJ, MC, and BW contributed to writing the paper. EK and HS performed experiments and analyzed data for this study. ML performed some of the ELISPOT assays described in the manuscript and analyzed the corresponding data. AY contributed to collecting patient samples. GA ran ELISPOTs and prepared samples that were used as data for the manuscript. XY was involved in performing the experiments. TMA determined entropy scores for sequence variability. YQ and MC provided relative hazards for the HLA alleles and performed correlation analyses.