About the Authors

Richard A Kronmal

Affiliation Collaborative Heath Studies Coordinating Center and Department of Biostatistics, University of Washington, Seattle, Washington, United States of America

Joshua I Barzilay

To whom correspondence should be addressed. E-mail: joshua.barzilay@kp.org

Affiliation Kaiser Permanente of Georgia and Division of Endocrinology, Emory University School of Medicine, Atlanta, Georgia, United States of America

Nicholas L Smith

Affiliation Department of Epidemiology, University of Washington, Seattle, Washington, United States of America

Bruce M Psaty

Affiliation Departments of Medicine, Epidemiology, and Health Services, University of Washington, Seattle, Washington, United States of America

Lewis H Kuller

Affiliation Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

Gregory L Burke

Affiliation Department of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America

Curt Furberg

Affiliation Department of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

RAK, JIB, BMP, and GLB designed the study. RAK and JIB analyzed the data. GLB enrolled patients. RAK, JIB, NLS, BMP, LHK, GLB, and CF contributed to writing the paper. RAK, BMP, LHK, GLB, and CF designed the CHS. BMP helped design CHS events data collection methods. BMP have been one of the investigators responsible for the review and classification of cardiovascular events and total mortality in CHS.