About the Authors

Rong-Ze Yang

Affiliation Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Mi-Jeong Lee

Affiliation Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Hong Hu

Affiliation Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Toni I Pollin

Affiliation Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Alice S Ryan

Affiliation Division of Gerontology, Geriatric Research, Education, and Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, Maryland, United States of America

Barbara J Nicklas

Affiliation Section on Gerontology and Geriatric Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America

Soren Snitker

Affiliation Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Richard B Horenstein

Affiliation Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Kristen Hull

Affiliation Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Nelson H Goldberg

Affiliation Division of Plastic and Reconstructive Surgery, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Andrew P Goldberg

Affiliation Division of Gerontology, Geriatric Research, Education, and Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, Maryland, United States of America

Alan R Shuldiner

Affiliations Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, United States of America , Division of Gerontology, Geriatric Research, Education, and Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, Maryland, United States of America

Susan K Fried

Affiliations Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, United States of America , Division of Gerontology, Geriatric Research, Education, and Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, Maryland, United States of America

Da-Wei Gong

To whom correspondence should be addressed. E-mail: dgong@medicine.umaryland.edu

Affiliation Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

RZY, MJL, ASR, BJN, APG, ARS, SKF, and DWG designed the study. RZY, MJL, HH, ASR, BJN, SS, RBH, KH, NHG, and DWG performed the experiments. RZY, MJL, TIP, ASR, BJN, and DWG analyzed the data. RZY, MJL, ASR, BJN, RBH, APG, ARS, SKF, and DWG contributed to writing the paper.