About the Authors

Yana Pikman

Affiliation Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Benjamin H Lee

Affiliation Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Thomas Mercher

Affiliation Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Elizabeth McDowell

Affiliation Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Benjamin L Ebert

Affiliations Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America , Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America

Maricel Gozo

Affiliation Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Adam Cuker

Affiliation Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Gerlinde Wernig

Affiliation Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Sandra Moore

Affiliation Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Ilene Galinsky

Affiliation Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America

Daniel J DeAngelo

Affiliation Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America

Jennifer J Clark

Affiliation Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America

Stephanie J Lee

Affiliation Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America

Todd R Golub

Affiliations Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America , Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America , Howard Hughes Medical Institute, Boston, Massachusetts, United States of America

Martha Wadleigh

Affiliation Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America

D. Gary Gilliland

Affiliations Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America , Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America , Howard Hughes Medical Institute, Boston, Massachusetts, United States of America

Ross L Levine

To whom correspondence should be addressed. E-mail: ross_levine@dfci.harvard.edu

Affiliations Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America , Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

YP, DGG, and RLL designed the study and wrote the manuscript. YP, BHL, TM, BLE, and RLL performed research and analyzed data. BHL and TM contributed to writing the manuscript. EMD, MG, AC, JJC, and MW performed research. SM provided technical assistance. IG, DJD, and JJC organized the collection of samples at Dana-Farber Cancer Institute. GW, SJL, TRG, and MW contributed to study design.