About the Authors

Verena Ilona Carrara

Affiliations Shoklo Malaria Research Unit, Tak, Thailand, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand, Departments of Medical Entomology, Tropical Hygiene and Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

Supakit Sirilak

Affiliation Public Health Office, Tak, Thailand

Janjira Thonglairuam

Affiliation Public Health Office, Tak, Thailand

Chaiporn Rojanawatsirivet

Affiliation Ministry of Public Health, Nonthaburi, Thailand

Stephane Proux

Affiliation Shoklo Malaria Research Unit, Tak, Thailand

Valery Gilbos

Affiliation Shoklo Malaria Research Unit, Tak, Thailand

Al Brockman

Affiliations Shoklo Malaria Research Unit, Tak, Thailand, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

Elizabeth A Ashley

Affiliations Shoklo Malaria Research Unit, Tak, Thailand, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand, Centre for Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, United Kingdom

Rose McGready

Affiliations Shoklo Malaria Research Unit, Tak, Thailand, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand, Centre for Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, United Kingdom

Srivicha Krudsood

Affiliation Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

Somjai Leemingsawat

Affiliation Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

Sornchai Looareesuwan

Affiliation Departments of Medical Entomology, Tropical Hygiene and Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

Pratap Singhasivanon

Affiliation Departments of Medical Entomology, Tropical Hygiene and Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

Nicholas White

Affiliations Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand, Centre for Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, United Kingdom

François Nosten

To whom correspondence should be addressed. E-mail: SMRU@tropmedres.ac

Affiliations Shoklo Malaria Research Unit, Tak, Thailand, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand, Centre for Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, United Kingdom

Competing Interests

NW is chairman of the World Health Organization malaria treatment guidelines committee and is on the editorial board of PLoS Medicine. The authors have no other conflict of interest to declare.

Author Contributions

S. Sirilak, P. Singhasivanon, N. White, and F. Nosten conceptualized and designed the project. V. I. Carrara coordinated the cross-sectional surveys, interpreted the results of all study components, and drafted the manuscript, with F. Nosten. J. Thonglairuam managed the data entry of the public health data and conducted preliminary results of morbidity and mortality. A. Brockman coordinated and analysed the in vitro studies, E. A. Ashley the in vivo studies, and R. McGready the studies related to pregnant women. S. Proux supervised and controlled the quality of all laboratory results. V. Gilbos developed and supervised the Information Education Communication programme. C. Rojanawatsirivet, S. Krudsood, S. Leemingsawat, and S. Looareesuwan coordinated and analysed part of the entomological data. All authors revised the manuscript for intellectual content.