About the Authors

Kristjana Einarsdóttir

Affiliations Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden , Population Genetics, Genome Institute of Singapore, Singapore

Keith Humphreys

Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

Carine Bonnard

Affiliation Population Genetics, Genome Institute of Singapore, Singapore

Juni Palmgren

Affiliations Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden , Department of Mathematics, Stockholm University, Stockholm, Sweden

Mark M Iles

Affiliation Genetic Epidemiology Division, Cancer Research UK Clinical Centre, St James's University Hospital, Leeds, United Kingdom

Arvid Sjölander

Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

Yuqing Li

Affiliation Population Genetics, Genome Institute of Singapore, Singapore

Kee Seng Chia

Affiliation Center for Molecular Epidemiology, Department of Community, Occupational and Family Medicine, National University of Singapore, Singapore

Edison T Liu

Affiliation Population Genetics, Genome Institute of Singapore, Singapore

Per Hall

Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

Jianjun Liu

To whom correspondence should be addressed. E-mail: liuj3@gis.a-star.edu.sg

Affiliation Population Genetics, Genome Institute of Singapore, Singapore

Sara Wedrén

Affiliations Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden , Population Genetics, Genome Institute of Singapore, Singapore , Center for Molecular Epidemiology, Department of Community, Occupational and Family Medicine, National University of Singapore, Singapore

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

KE, JL, and SW wrote the article. KE and KH performed the statistical analyses with the assistance of JP, MMI, and AS. CB oversaw the genotyping procedures, and KE assisted with the genotyping. KE and YL selected the polymorphisms. JL and SW coordinated the study. KH, JP, KSC, ETL, PH, JL, and SW contributed to conception and design of the project and critically revised the manuscript. All authors read and approved the final manuscript.