About the Authors

Jiaqi Tang

Contributed equally to this work with: Jiaqi Tang, Changjun Wang, Youjun Feng, Weizhong Yang, Huaidong Song, Zhihai Chen, Hongjie Yu

To whom correspondence should be addressed. E-mail: gaof@im.ac.cn (GFG), E-mail: tjq85@hotmail.com (JT), E-mail: xnwang@21cn.net (XW), E-mail: wangyu@chinacdc.net.cn (YW).

Affiliation Department of Epidemiology, Research Institute for Medicine of Nanjing Command, Nanjing, China

Changjun Wang

Contributed equally to this work with: Jiaqi Tang, Changjun Wang, Youjun Feng, Weizhong Yang, Huaidong Song, Zhihai Chen, Hongjie Yu

Affiliation Department of Epidemiology, Research Institute for Medicine of Nanjing Command, Nanjing, China

Youjun Feng

Contributed equally to this work with: Jiaqi Tang, Changjun Wang, Youjun Feng, Weizhong Yang, Huaidong Song, Zhihai Chen, Hongjie Yu

Affiliations Center for Molecular Immunology and State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China , Graduate School, Chinese Academy of Sciences, Beijing, China

Weizhong Yang

Contributed equally to this work with: Jiaqi Tang, Changjun Wang, Youjun Feng, Weizhong Yang, Huaidong Song, Zhihai Chen, Hongjie Yu

Affiliation Chinese Center for Disease Control and Prevention (China CDC), Beijing, China

Huaidong Song

Contributed equally to this work with: Jiaqi Tang, Changjun Wang, Youjun Feng, Weizhong Yang, Huaidong Song, Zhihai Chen, Hongjie Yu

Affiliations State Key Laboratory of Medical Genomics, Ruijin Hospital Affiliated to Medical School of Shanghai Jiao-Tong University, Shanghai, China , Chinese National Human Genome Center, Shanghai, China

Zhihai Chen

Contributed equally to this work with: Jiaqi Tang, Changjun Wang, Youjun Feng, Weizhong Yang, Huaidong Song, Zhihai Chen, Hongjie Yu

Affiliation Beijing Ditan Hospital, Beijing, China

Hongjie Yu

Contributed equally to this work with: Jiaqi Tang, Changjun Wang, Youjun Feng, Weizhong Yang, Huaidong Song, Zhihai Chen, Hongjie Yu

Affiliation Chinese Center for Disease Control and Prevention (China CDC), Beijing, China

Xiuzhen Pan

Affiliation Department of Epidemiology, Research Institute for Medicine of Nanjing Command, Nanjing, China

Xiaojun Zhou

Affiliation Department of Pathology, Jinling Hospital of Nanjing, Nanjing, China

Huaru Wang

Affiliation Department of Epidemiology, Research Institute for Medicine of Nanjing Command, Nanjing, China

Bo Wu

Affiliation Department of Pathology, Jinling Hospital of Nanjing, Nanjing, China

Haili Wang

Affiliation Department of Epidemiology, Research Institute for Medicine of Nanjing Command, Nanjing, China

Huamei Zhao

Affiliation Department of Epidemiology, Research Institute for Medicine of Nanjing Command, Nanjing, China

Ying Lin

Affiliation School of Biosciences and Bioengineering, South China University of Technology, Guangzhou, China

Jianhua Yue

Affiliation Department of Epidemiology, Research Institute for Medicine of Nanjing Command, Nanjing, China

Zhenqiang Wu

Affiliation School of Biosciences and Bioengineering, South China University of Technology, Guangzhou, China

Xiaowei He

Affiliation School of Biosciences and Bioengineering, South China University of Technology, Guangzhou, China

Feng Gao

Affiliation Center for Molecular Immunology and State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China

Abdul Hamid Khan

Affiliations Center for Molecular Immunology and State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China , Graduate School, Chinese Academy of Sciences, Beijing, China

Jian Wang

Affiliation Beijing Genomics Institute, Chinese Academy of Sciences, Beijing, China

Guo-Ping Zhao

Affiliation Chinese National Human Genome Center, Shanghai, China

Yu Wang

To whom correspondence should be addressed. E-mail: gaof@im.ac.cn (GFG), E-mail: tjq85@hotmail.com (JT), E-mail: xnwang@21cn.net (XW), E-mail: wangyu@chinacdc.net.cn (YW).

Affiliation Chinese Center for Disease Control and Prevention (China CDC), Beijing, China

Xiaoning Wang

To whom correspondence should be addressed. E-mail: gaof@im.ac.cn (GFG), E-mail: tjq85@hotmail.com (JT), E-mail: xnwang@21cn.net (XW), E-mail: wangyu@chinacdc.net.cn (YW).

Affiliation School of Biosciences and Bioengineering, South China University of Technology, Guangzhou, China

Zhu Chen

Affiliations State Key Laboratory of Medical Genomics, Ruijin Hospital Affiliated to Medical School of Shanghai Jiao-Tong University, Shanghai, China , Chinese National Human Genome Center, Shanghai, China

George F Gao

To whom correspondence should be addressed. E-mail: gaof@im.ac.cn (GFG), E-mail: tjq85@hotmail.com (JT), E-mail: xnwang@21cn.net (XW), E-mail: wangyu@chinacdc.net.cn (YW).

Affiliation Center for Molecular Immunology and State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Jiaqi Tang, Changjun Wang, Weizhong Yang, Zhihai Chen, Hongjie Yu, Xiaojun Zhou, Bo Wu, and Yu Wang did the clinical investigation in the field. Jiaqi Tang, Zhu Chen, Jian Wang, Guo-Ping Zhao, Xiaoning Wang, and George F. Gao designed the study. Changjun Wang, Youjun Feng, Huaidong Song, Xiaojun Zhou, Huaru Wang, Bo Wu, Haili Wang, Huamei Zhao, Ying Lin, and Jianhua Yue performed the experiments. Changjun Wang, Youjun Feng, Xiuzhen Pan, Zhenqiang Wu, Xiaowei He, Feng Gao, and Abdul Hamid Khan analyzed the data. Jiaqi Tang, Youjun Feng, and George F. Gao wrote the paper.