About the Authors

Patrick Vallance

patrick.5.vallance@gsk.com

Affiliation President R&D, GlaxoSmithKline, Brentford, Middlesex, United Kingdom

Andrew Freeman

Affiliation Head Medical Policy, GlaxoSmithKline, Brentford, Middlesex, United Kingdom

Murray Stewart

Affiliation Chief Medical Officer GlaxoSmithKline, Collegeville, Pennsylvania, United States of America

Competing Interests

We have read the journal's policy and have the following conflicts: PV is a President at GlaxoSmithKline and holds stock or stock options in GlaxoSmithKline. AF is Head of Medical Policy at GlaxoSmithKline and holds stock or stock options in GlaxoSmithKline. MS is Chief Medical Officer at GlaxoSmithKline and holds stock or stock options in GlaxoSmithKline. PV is a member of the Editorial Board of PLOS Medicine.

Author Contributions

Wrote the first draft of the manuscript: PV AF MS. Contributed to the writing of the manuscript: PV AF MS. Agree with the manuscript’s results and conclusions: PV AF MS. All authors have read, and confirm that they meet, ICMJE criteria for authorship.