About the Authors
- Katherine E. Tansey
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Affiliation Institute of Psychiatry, King's College London, London, United Kingdom
- Michel Guipponi
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Affiliation Department of Genetic Medicine and Laboratories, University Hospitals of Geneva, Geneva, Switzerland
- Nader Perroud
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Affiliation Department of Psychiatry, University of Geneva, Geneva, Switzerland
- Guido Bondolfi
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Affiliation Department of Psychiatry, University of Geneva, Geneva, Switzerland
- Enrico Domenici
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Affiliations Center of Excellence for Drug Discovery in Psychiatry, GlaxoSmithKline Medicines Research Centre, Verona, Italy, Pharma Research and Early Development, F. Hoffmann–La Roche, Basel, Switzerland
- David Evans
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Affiliation Medical Research Council CAiTE Centre, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
- Stephanie K. Hall
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Affiliation Molecular Medicine, Pfizer, Groton, Connecticut, United States of America
- Joanna Hauser
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Affiliation Laboratory of Psychiatric Genetics, Poznan University of Medical Sciences, Poznan, Poland
- Neven Henigsberg
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Affiliation Croatian Institute for Brain Research, Medical School, University of Zagreb, Zagreb, Croatia
- Xiaolan Hu
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Affiliation Molecular Medicine, Pfizer, Groton, Connecticut, United States of America
- Borut Jerman
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Affiliations Department of Molecular and Biomedical Sciences, Jozef Stefan Institute, Ljubljana, Slovenia, Institute of Public Health of the Republic of Slovenia, Ljubljana, Slovenia
- Wolfgang Maier
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Affiliation Department of Psychiatry, University of Bonn, Bonn, Germany
- Ole Mors
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Affiliation Centre for Psychiatric Research, Aarhus University Hospital, Risskov, Denmark
- Michael O'Donovan
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Affiliation Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Department of Psychological Medicine and Neurology, School of Medicine, Cardiff University, Cardiff, United Kingdom
- Tim J. Peters
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Affiliation School of Clinical Sciences, University of Bristol, Bristol, United Kingdom
- Anna Placentino
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Affiliation Psychiatric Unit 23, Department of Mental Health, Spedali Civili Hospital and Biological Psychiatry Unit, Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy
- Marcella Rietschel
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Affiliation Central Institute of Mental Health, Division of Genetic Epidemiology in Psychiatry, Mannheim, Germany
- Daniel Souery
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Affiliation Department of Psychiatry, Erasme Academic Hospital, Université Libre de Bruxelles, Brussels, Belgium
- Katherine J. Aitchison
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Affiliations Institute of Psychiatry, King's College London, London, United Kingdom, Department of Psychiatry, University of Alberta, Edmonton, Alberta, Canada
- Ian Craig
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Affiliation Institute of Psychiatry, King's College London, London, United Kingdom
- Anne Farmer
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Affiliation Institute of Psychiatry, King's College London, London, United Kingdom
- Jens R. Wendland
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Affiliation Pharma Research and Early Development, F. Hoffmann–La Roche, Basel, Switzerland
- Alain Malafosse
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Affiliations Department of Genetic Medicine and Laboratories, University Hospitals of Geneva, Geneva, Switzerland, Department of Psychiatry, University of Geneva, Geneva, Switzerland
- Peter Holmans
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Affiliation Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Department of Psychological Medicine and Neurology, School of Medicine, Cardiff University, Cardiff, United Kingdom
- Glyn Lewis
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Affiliation School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
- Cathryn M. Lewis
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Affiliation Institute of Psychiatry, King's College London, London, United Kingdom
- Tine Bryan Stensbøl
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Affiliation Discovery Pharmacology Research, H. Lundbeck A/S, Copenhagen, Denmark
- Shitij Kapur
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Affiliation Institute of Psychiatry, King's College London, London, United Kingdom
- Peter McGuffin
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Affiliation Institute of Psychiatry, King's College London, London, United Kingdom
- Rudolf Uher
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* E-mail: rudolf.uher@kcl.ac.uk
Affiliations Institute of Psychiatry, King's College London, London, United Kingdom, Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada
Competing Interests
GB is a member of a national advisory board for Bristol-Myer Squibb and Pfizer and has received research funding from GlaxoSmithKline, Wyeth-Lederle, Bristol-Myers-Squibb, and Sanofi Aventis. ED and JRW are full-time employees of Roche. ED was a full time employee of GlaxoSmithKline when he undertook work on this study. SKH and XH are full-time employees of Pfizer. NH has participated in clinical trials sponsored by pharmaceutical companies including GlaxoSmithKline and Lundbeck and received honoraria for participating in expert panels from pharmaceutical companies including Lundbeck. MO’D's department received £2000 in lieu of an honorarium to MO'D from Lilly as a result of his participation in sponsored symposia in 2012. Those symposia were unrelated to the contents of this manuscript. MO’D holds grants from the Medical Research Council (UK), The Wellcome Trust, the National Institutes of Medicine (USA), and the European Union. None are relevant to the contents of this manuscript. DS is a member of a national advisory boards for Astra-Zeneca, Bristol-Myers Squibb, Eli Lilly, and Lundbeck. KJA is a member of a national advisory board for Johnson & Johnson, Lundbeck, Roche Diagnostics, and Bristol-Myers Squibb and Otsuka Pharmaceuticals Limited and has received consultancy fees and honoraria from Bristol-Myers Squibb, Lundbeck, Roche Molecular Systems, Roche Diagnostics, and Johnson & Johnson. KJA has received research and development consultancy fees and research support from Roche Diagnostics and Roche Molecular Systems. KJA has received research grants from Bristol-Myers Squibb and Otsuka Pharmaceuticals Limited; Johnson & Johnson Pharmaceutical Research and Development. PM and AF have previously received consultancy fees and honoraria for participating in expert panels from pharmaceutical companies including Lundbeck and GlaxoSmithKline, but have had no such income in the last 3 years. CML is on the Editorial Board of PLOS Medicine. TBS is a full time employee of Lundbeck. SK has received research funding from AstraZeneca, Bristol-Myers Squibb, and GlaxoSmithKline, and has served as consultant and/or speaker for AstraZeneca, Bioline, BMS-Otsuka, Eli Lilly, Janssen, Lundbeck, NeuroSearch, Pfizer, Roche, Servier, and Solvay Wyeth. All other authors have declared that no competing interests exist.
Author Contributions
Conceived and designed the experiments: RU PM JRW TBS SK. Performed the experiments: MG. Analyzed the data: KET PH. Contributed reagents/materials/analysis tools: NP GB ED DE SKH JH NH XH BJ WM OM MO'D TJP AP MR DS KJA IC AF AM GL PM. Wrote the first draft of the manuscript: KET RU. Contributed to the writing of the manuscript: KET MG NP GB ED DE SKH JH NH XH BJ WM OM MO'D TJP AP MR DS KJA IC AF JRW AM PH GL CML TBS SK PM RU. ICMJE criteria for authorship read and met: KET MG NP GB ED DE SKH JH NH XH BJ WM OM MO'D TJP AP MR DS KJA IC AF JRW AM PH GL CML TBS SK PM RU. Agree with manuscript results and conclusions: KET MG NP GB ED DE SKH JH NH XH BJ WM OM MO'D TJP AP MR DS KJA IC AF JRW AM PH GL CML TBS SK PM RU. Supervised the statistical analyses: CML.