Table of Contents: July 2006

Scanning EM micrograph of a Caenorhabditis elegans wild-type adult. Research reported by Brock et al. It describes a novel nuclear hormone receptor that regulates transcription of fatty acid desaturase genes in C. elegans. This regulation is necessary to maintain optimal membrane fatty acid composition.

Image Credit: EM micrograph and false coloring by Trisha J. Brock.


Modeling Chromosomes in Mouse to Explore the Function of Genes, Genomic Disorders, and Chromosomal Organization

Véronique Brault, Patricia Pereira, Arnaud Duchon, Yann Hérault

Matrix-Assisted Laser Desorption/Ionisation, Time-of-Flight Mass Spectrometry in Genomics Research

Jiannis Ragoussis, Gareth P Elvidge, Kulvinder Kaur, Stefano Colella

Research Articles

Human Imprinted Chromosomal Regions Are Historical Hot-Spots of Recombination

Ionel Sandovici, Sacha Kassovska-Bratinova, Joe E Vaughan, Rae Stewart, Mark Leppert, Carmen Sapienza

Neofunctionalization in Vertebrates: The Example of Retinoic Acid Receptors

Hector Escriva, Stéphanie Bertrand, Pierre Germain, Marc Robinson-Rechavi, Muriel Umbhauer, Jérôme Cartry, Marilyne Duffraisse, Linda Holland, Hinrich Gronemeyer, Vincent Laudet

Possible Ancestral Structure in Human Populations

Vincent Plagnol, Jeffrey D Wall

Potent Induction of Arabidopsis thaliana Flowering by Elevated Growth Temperature

Sureshkumar Balasubramanian, Sridevi Sureshkumar, Janne Lempe, Detlef Weigel

Lymphotoxin-α Gene and Risk of Myocardial Infarction in 6,928 Cases and 2,712 Controls in the ISIS Case-Control Study

Robert Clarke, Peng Xu, Derrick Bennett, Sarah Lewington, Krina Zondervan, Sarah Parish, Alison Palmer, Sarah Clark, Lon Cardon, Richard Peto, Mark Lathrop, Rory Collins

Genetic Regulation of Unsaturated Fatty Acid Composition in C. elegans

Trisha J Brock, John Browse, Jennifer L Watts

The Ancestral Eutherian Karyotype Is Present in Xenarthra

Marta Svartman, Gary Stone, Roscoe Stanyon

Structural Model Analysis of Multiple Quantitative Traits

Renhua Li, Shirng-Wern Tsaih, Keith Shockley, Ioannis M Stylianou, Jon Wergedal, Beverly Paigen, Gary A Churchill

Transcriptional Profiling of Aging in Human Muscle Reveals a Common Aging Signature

Jacob M Zahn, Rebecca Sonu, Hannes Vogel, Emily Crane, Krystyna Mazan-Mamczarz, Ralph Rabkin, Ronald W Davis, Kevin G Becker, Art B Owen, Stuart K Kim

Lysine 63-Polyubiquitination Guards against Translesion Synthesis–Induced Mutations

Roland K Chiu, Jan Brun, Chantal Ramaekers, Jan Theys, Lin Weng, Philippe Lambin, Douglas A Gray, Bradly G Wouters

Genome-Wide Analysis of Gene Expression during Early Arabidopsis Flower Development

Frank Wellmer, Márcio Alves-Ferreira, Annick Dubois, José Luis Riechmann, Elliot M Meyerowitz

Anatomic Demarcation by Positional Variation in Fibroblast Gene Expression Programs

John L Rinn, Chanda Bondre, Hayes B Gladstone, Patrick O Brown, Howard Y Chang

Who Ate Whom? Adaptive Helicobacter Genomic Changes That Accompanied a Host Jump from Early Humans to Large Felines

Mark Eppinger, Claudia Baar, Bodo Linz, Günter Raddatz, Christa Lanz, Heike Keller, Giovanna Morelli, Helga Gressmann, Mark Achtman, Stephan C Schuster

Haplotype Block Structure Is Conserved across Mammals

Victor Guryev, Bart M. G Smits, Jose van de Belt, Mark Verheul, Norbert Hubner, Edwin Cuppen


Correction: The Life-Cycle of Operons

Morgan N Price, Adam P Arkin, Eric J Alm

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