Figures
The crystal structure of a short DNA helix methylated on both strands at the center cytosine
The image displays the crystal structure of a short DNA helix methylated on both strands at the center cytosine. The in vivo methylation state of CpG islands within the human genome is highly correlated with DNA sequence and structure (see Bock et al.).
Image Credit: Designed by Christoph Bock. The structure was taken from the Protein Data Bank (accession number 329D), with rendering using PyMOL and POV-Ray and postprocessing in Adobe Photoshop.
Citation: (2006) PLoS Genetics Issue Image | Vol. 2(3) March 2006. PLoS Genet 2(3): ev02.i03. https://doi.org/10.1371/image.pgen.v02.i03
Published: March 31, 2006
Copyright: © 2006 Bock et al.. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The image displays the crystal structure of a short DNA helix methylated on both strands at the center cytosine. The in vivo methylation state of CpG islands within the human genome is highly correlated with DNA sequence and structure (see Bock et al.).
Image Credit: Designed by Christoph Bock. The structure was taken from the Protein Data Bank (accession number 329D), with rendering using PyMOL and POV-Ray and postprocessing in Adobe Photoshop.