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PLoS Genetics Issue Image | Vol. 8(7) July 2012

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Fungal development.

The mold Aspergillus nidulans grows as filaments (yellow) with the potential for several developmental pathways: asexual spores (green) will be released into the air, and sexual spores are produced within fruiting bodies (purple), which are nursed by round Hülle cells (brown). In this issue, Bayram et al. demonstrate that the Fus3 mitogen-activated protein kinase (MAPK) of this filamentous fungus controls nuclear regulators to coordinate sexual development and secondary metabolism. Signal transduction requires that several kinases migrate as the MAPK module from the membrane to the nuclear envelope where only Fus3 enters the nucleus.

Image Credit: Özgür Bayram and Gerhard H. Braus (Georg–August–Universität).

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Fungal development.

The mold Aspergillus nidulans grows as filaments (yellow) with the potential for several developmental pathways: asexual spores (green) will be released into the air, and sexual spores are produced within fruiting bodies (purple), which are nursed by round Hülle cells (brown). In this issue, Bayram et al. demonstrate that the Fus3 mitogen-activated protein kinase (MAPK) of this filamentous fungus controls nuclear regulators to coordinate sexual development and secondary metabolism. Signal transduction requires that several kinases migrate as the MAPK module from the membrane to the nuclear envelope where only Fus3 enters the nucleus.

Image Credit: Özgür Bayram and Gerhard H. Braus (Georg–August–Universität).

https://doi.org/10.1371/image.pgen.v08.i07.g001