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Open Access
Peer-reviewed
Research Article
Integrating Genome-Wide Genetic Variations and Monocyte Expression Data Reveals Trans-Regulated Gene Modules in Humans
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Maxime Rotival ,
Contributed equally to this work with: Maxime Rotival, Tanja Zeller, Philipp S. Wild
Affiliation INSERM UMRS 937, Pierre and Marie Curie University (UPMC, Paris 6) and Medical School, Paris, France
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Tanja Zeller ,
Contributed equally to this work with: Maxime Rotival, Tanja Zeller, Philipp S. Wild
Current address: Department of General and Interventional Cardiology, University Heart Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
Affiliation II. Medizinische Klinik und Poliklinik, Universitätsmedizin der Johannes-Gutenberg Universität Mainz, Mainz, Germany
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Philipp S. Wild ,
Contributed equally to this work with: Maxime Rotival, Tanja Zeller, Philipp S. Wild
Affiliation II. Medizinische Klinik und Poliklinik, Universitätsmedizin der Johannes-Gutenberg Universität Mainz, Mainz, Germany
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Seraya Maouche,
Affiliation Medizinische Klinik II, Universität Lübeck, Lübeck, Germany
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Silke Szymczak,
Affiliation Institut für Medizinische Biometrie und Statistik, Universität Lübeck, Lübeck, Germany
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Arne Schillert,
Affiliation Institut für Medizinische Biometrie und Statistik, Universität Lübeck, Lübeck, Germany
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Raphaele Castagné,
Affiliation INSERM UMRS 937, Pierre and Marie Curie University (UPMC, Paris 6) and Medical School, Paris, France
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Arne Deiseroth,
Affiliation II. Medizinische Klinik und Poliklinik, Universitätsmedizin der Johannes-Gutenberg Universität Mainz, Mainz, Germany
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Carole Proust,
Affiliation INSERM UMRS 937, Pierre and Marie Curie University (UPMC, Paris 6) and Medical School, Paris, France
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Jessy Brocheton,
Affiliation INSERM UMRS 937, Pierre and Marie Curie University (UPMC, Paris 6) and Medical School, Paris, France
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Tiphaine Godefroy,
Affiliation INSERM UMRS 937, Pierre and Marie Curie University (UPMC, Paris 6) and Medical School, Paris, France
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Claire Perret,
Affiliation INSERM UMRS 937, Pierre and Marie Curie University (UPMC, Paris 6) and Medical School, Paris, France
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Marine Germain,
Affiliation INSERM UMRS 937, Pierre and Marie Curie University (UPMC, Paris 6) and Medical School, Paris, France
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Medea Eleftheriadis,
Affiliation II. Medizinische Klinik und Poliklinik, Universitätsmedizin der Johannes-Gutenberg Universität Mainz, Mainz, Germany
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Christoph R. Sinning,
Current address: Department of General and Interventional Cardiology, University Heart Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
Affiliation II. Medizinische Klinik und Poliklinik, Universitätsmedizin der Johannes-Gutenberg Universität Mainz, Mainz, Germany
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Renate B. Schnabel,
Current address: Department of General and Interventional Cardiology, University Heart Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
Affiliation II. Medizinische Klinik und Poliklinik, Universitätsmedizin der Johannes-Gutenberg Universität Mainz, Mainz, Germany
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Edith Lubos,
Current address: Department of General and Interventional Cardiology, University Heart Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
Affiliation II. Medizinische Klinik und Poliklinik, Universitätsmedizin der Johannes-Gutenberg Universität Mainz, Mainz, Germany
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Karl J. Lackner,
Affiliation Institut für Klinische Chemie und Laboratoriumsmedizin, Universitätsmedizin der Johannes-Gutenberg Universität Mainz, Mainz, Germany
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Heidi Rossmann,
Affiliation Institut für Klinische Chemie und Laboratoriumsmedizin, Universitätsmedizin der Johannes-Gutenberg Universität Mainz, Mainz, Germany
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Thomas Münzel,
Affiliation II. Medizinische Klinik und Poliklinik, Universitätsmedizin der Johannes-Gutenberg Universität Mainz, Mainz, Germany
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Augusto Rendon,
Affiliations Department of Haematology, University of Cambridge and National Health Service Blood and Transplant, Cambridge, United Kingdom, MRC Biostatistics Unit, Cambridge, United Kingdom
⨯ - Cardiogenics Consortium,
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Jeanette Erdmann,
Affiliation Medizinische Klinik II, Universität Lübeck, Lübeck, Germany
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Panos Deloukas,
Affiliation Human Genetics, Wellcome Trust Sanger Institute, Hinxton, United Kingdom
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Christian Hengstenberg,
Affiliation Klinik und Poliklinik für Innere Medizin II, Universität Regensburg, Regensburg, Germany
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Patrick Diemert,
Current address: Department of General and Interventional Cardiology, University Heart Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
Affiliation Medizinische Klinik II, Universität Lübeck, Lübeck, Germany
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Gilles Montalescot,
Affiliation INSERM UMRS 937, Pierre and Marie Curie University (UPMC, Paris 6) and Medical School, Paris, France
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Willem H. Ouwehand,
Affiliations Department of Haematology, University of Cambridge and National Health Service Blood and Transplant, Cambridge, United Kingdom, Human Genetics, Wellcome Trust Sanger Institute, Hinxton, United Kingdom
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Nilesh J. Samani,
Affiliations Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom, Leicester NIHR Biomedical Research Unit in Cardiovascular Disease, Leicester, United Kingdom
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Heribert Schunkert,
Affiliation Medizinische Klinik II, Universität Lübeck, Lübeck, Germany
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David-Alexandre Tregouet,
Affiliation INSERM UMRS 937, Pierre and Marie Curie University (UPMC, Paris 6) and Medical School, Paris, France
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Andreas Ziegler,
Affiliation Institut für Medizinische Biometrie und Statistik, Universität Lübeck, Lübeck, Germany
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Alison H. Goodall,
Affiliations Department of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom, Leicester NIHR Biomedical Research Unit in Cardiovascular Disease, Leicester, United Kingdom
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François Cambien,
Affiliation INSERM UMRS 937, Pierre and Marie Curie University (UPMC, Paris 6) and Medical School, Paris, France
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Laurence Tiret ,
* E-mail: laurence.tiret@upmc.fr (L Tiret); s.blankenberg@uke.de (S Blankenberg)
¶These authors also contributed equally to this work.
Affiliation INSERM UMRS 937, Pierre and Marie Curie University (UPMC, Paris 6) and Medical School, Paris, France
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Stefan Blankenberg
* E-mail: laurence.tiret@upmc.fr (L Tiret); s.blankenberg@uke.de (S Blankenberg)
Current address: Department of General and Interventional Cardiology, University Heart Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
¶These authors also contributed equally to this work.
Affiliation II. Medizinische Klinik und Poliklinik, Universitätsmedizin der Johannes-Gutenberg Universität Mainz, Mainz, Germany
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Integrating Genome-Wide Genetic Variations and Monocyte Expression Data Reveals Trans-Regulated Gene Modules in Humans
- Maxime Rotival,
- Tanja Zeller,
- Philipp S. Wild,
- Seraya Maouche,
- Silke Szymczak,
- Arne Schillert,
- Raphaele Castagné,
- Arne Deiseroth,
- Carole Proust,
- Jessy Brocheton
- Published: December 1, 2011
- https://doi.org/10.1371/journal.pgen.1002367