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The Genome of a Pathogenic Rhodococcus: Cooptive Virulence Underpinned by Key Gene Acquisitions

  • Michal Letek,

    Affiliation Microbial Pathogenesis Unit, Centres for Infectious Diseases and Immunity, Infection, and Evolution, University of Edinburgh, Edinburgh, United Kingdom

  • Patricia González,

    Affiliations Microbial Pathogenesis Unit, Centres for Infectious Diseases and Immunity, Infection, and Evolution, University of Edinburgh, Edinburgh, United Kingdom, Irish Equine Centre, Johnstown, Naas, Ireland

  • Iain MacArthur,

    Affiliations Microbial Pathogenesis Unit, Centres for Infectious Diseases and Immunity, Infection, and Evolution, University of Edinburgh, Edinburgh, United Kingdom, Irish Equine Centre, Johnstown, Naas, Ireland, Department of Pathobiology, University of Guelph, Guelph, Canada

  • Héctor Rodríguez,

    Affiliations Microbial Pathogenesis Unit, Centres for Infectious Diseases and Immunity, Infection, and Evolution, University of Edinburgh, Edinburgh, United Kingdom, Irish Equine Centre, Johnstown, Naas, Ireland

  • Tom C. Freeman,

    Affiliation Division of Genetics and Genomics, Roslin BioCentre, University of Edinburgh, Edinburgh, United Kingdom

  • Ana Valero-Rello,

    Affiliations Microbial Pathogenesis Unit, Centres for Infectious Diseases and Immunity, Infection, and Evolution, University of Edinburgh, Edinburgh, United Kingdom, Irish Equine Centre, Johnstown, Naas, Ireland

  • Mónica Blanco,

    Affiliations Microbial Pathogenesis Unit, Centres for Infectious Diseases and Immunity, Infection, and Evolution, University of Edinburgh, Edinburgh, United Kingdom, Irish Equine Centre, Johnstown, Naas, Ireland

  • Tom Buckley,

    Affiliation Irish Equine Centre, Johnstown, Naas, Ireland

  • Inna Cherevach,

    Affiliation Pathogen Genomics, Wellcome Trust Sanger Institute, Cambridge, United Kingdom

  • Ruth Fahey,

    Affiliation School of Biomolecular and Biomedical Sciences, University College Dublin, Dublin, Ireland

  • Alexia Hapeshi,

    Affiliation Microbial Pathogenesis Unit, Centres for Infectious Diseases and Immunity, Infection, and Evolution, University of Edinburgh, Edinburgh, United Kingdom

  • Jolyon Holdstock,

    Affiliation Oxford Gene Technology, Begbroke Science Park, Oxford, United Kingdom

  • Desmond Leadon,

    Affiliation Irish Equine Centre, Johnstown, Naas, Ireland

  • Jesús Navas,

    Affiliation Departamento de Biología Molecular, Universidad de Cantabria, Santander, Spain

  • Alain Ocampo,

    Affiliation Irish Equine Centre, Johnstown, Naas, Ireland

  • Michael A. Quail,

    Affiliation Pathogen Genomics, Wellcome Trust Sanger Institute, Cambridge, United Kingdom

  • Mandy Sanders,

    Affiliation Pathogen Genomics, Wellcome Trust Sanger Institute, Cambridge, United Kingdom

  • Mariela M. Scortti,

    Affiliations Microbial Pathogenesis Unit, Centres for Infectious Diseases and Immunity, Infection, and Evolution, University of Edinburgh, Edinburgh, United Kingdom, Departamento de Bioquímica y Biología Molecular IV, Universidad Complutense, Madrid, Spain

  • John F. Prescott,

    Affiliation Department of Pathobiology, University of Guelph, Guelph, Canada

  • Ursula Fogarty,

    Affiliation Irish Equine Centre, Johnstown, Naas, Ireland

  • Wim G. Meijer,

    Affiliation School of Biomolecular and Biomedical Sciences, University College Dublin, Dublin, Ireland

  • Julian Parkhill,

    Affiliation Pathogen Genomics, Wellcome Trust Sanger Institute, Cambridge, United Kingdom

  • Stephen D. Bentley,

    Affiliation Pathogen Genomics, Wellcome Trust Sanger Institute, Cambridge, United Kingdom

  •  [ ... ],
  • José A. Vázquez-Boland

    v.boland@ed.ac.uk

    Affiliations Microbial Pathogenesis Unit, Centres for Infectious Diseases and Immunity, Infection, and Evolution, University of Edinburgh, Edinburgh, United Kingdom, Grupo de Patogenómica Bacteriana, Universidad de León, León, Spain

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The Genome of a Pathogenic Rhodococcus: Cooptive Virulence Underpinned by Key Gene Acquisitions

  • Michal Letek, 
  • Patricia González, 
  • Iain MacArthur, 
  • Héctor Rodríguez, 
  • Tom C. Freeman, 
  • Ana Valero-Rello, 
  • Mónica Blanco, 
  • Tom Buckley, 
  • Inna Cherevach, 
  • Ruth Fahey
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