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Genetic Analysis of Human Traits In Vitro: Drug Response and Gene Expression in Lymphoblastoid Cell Lines

  • Edwin Choy ,

    Contributed equally to this work with: Edwin Choy, Roman Yelensky

    Affiliations Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Division of Hematology Oncology, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

  • Roman Yelensky ,

    Contributed equally to this work with: Edwin Choy, Roman Yelensky

    Affiliations Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Harvard–MIT Division of Health Sciences and Technology, Cambridge, Massachusetts, United States of America

  • Sasha Bonakdar,

    Affiliation Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

  • Robert M. Plenge,

    Affiliations Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

  • Richa Saxena,

    Affiliations Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

  • Philip L. De Jager,

    Affiliations Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Division of Molecular Immunology, Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America, Harvard Medical School–Partners Healthcare Center for Genetics and Genomics, Boston, Massachusetts, United States of America

  • Stanley Y. Shaw,

    Affiliations Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America, Center for Systems Biology and Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, United States of America

  • Cara S. Wolfish,

    Affiliations Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Division of Molecular Immunology, Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

  • Jacqueline M. Slavik,

    Affiliations Division of Molecular Immunology, Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, Massachusetts, United States of America, Biomedical Research Institute, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

  • Chris Cotsapas,

    Affiliations Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America

  • Manuel Rivas,

    Affiliations Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Department of Mathematics, Massachusetts Institute of Technology, Cambridge, Massachusetts, United Sates of America

  • Emmanouil T. Dermitzakis,

    Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, United Kingdom

  • Ellen Cahir-McFarland,

    Affiliations Harvard Medical School, Boston, Massachusetts, United States of America, Channing Laboratory and Infectious Disease Division, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

  • Elliott Kieff,

    Affiliations Harvard Medical School, Boston, Massachusetts, United States of America, Channing Laboratory and Infectious Disease Division, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

  • David Hafler,

    Affiliations Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Division of Molecular Immunology, Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

  • Mark J. Daly,

    Affiliations Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America

  •  [ ... ],
  • David Altshuler

    altshuler@molbio.mgh.harvard.edu

    Affiliations Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America, Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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Genetic Analysis of Human Traits In Vitro: Drug Response and Gene Expression in Lymphoblastoid Cell Lines

  • Edwin Choy, 
  • Roman Yelensky, 
  • Sasha Bonakdar, 
  • Robert M. Plenge, 
  • Richa Saxena, 
  • Philip L. De Jager, 
  • Stanley Y. Shaw, 
  • Cara S. Wolfish, 
  • Jacqueline M. Slavik, 
  • Chris Cotsapas
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