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A Role for Oxidized DNA Precursors in Huntington's Disease–Like Striatal Neurodegeneration

  • Gabriele De Luca ,

    Contributed equally to this work with: Gabriele De Luca, Maria Teresa Russo

    Affiliation Department of Environment and Primary Prevention, Experimental Carcinogenesis Division, Istituto Superiore di Sanità, Rome, Italy

  • Maria Teresa Russo ,

    Contributed equally to this work with: Gabriele De Luca, Maria Teresa Russo

    Affiliation Department of Environment and Primary Prevention, Experimental Carcinogenesis Division, Istituto Superiore di Sanità, Rome, Italy

  • Paolo Degan,

    Affiliation Department of Translational Oncology, Istituto Nazionale per la Ricerca sul Cancro (IST-CBA), Genova, Italy

  • Cecilia Tiveron,

    Affiliation European Brain Research Institute, Rome, Italy

  • Andrea Zijno,

    Affiliation Department of Environment and Primary Prevention, Experimental Carcinogenesis Division, Istituto Superiore di Sanità, Rome, Italy

  • Ettore Meccia,

    Affiliation Department of Environment and Primary Prevention, Experimental Carcinogenesis Division, Istituto Superiore di Sanità, Rome, Italy

  • Ilenia Ventura,

    Affiliation Department of Environment and Primary Prevention, Experimental Carcinogenesis Division, Istituto Superiore di Sanità, Rome, Italy

  • Elisabetta Mattei,

    Affiliation Institute of Neurobiology and Molecular Medicine, CNR, Rome, Italy

  • Yusaku Nakabeppu,

    Affiliation Division of Neurofunctional Genomics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan

  • Marco Crescenzi,

    Affiliation Department of Environment and Primary Prevention, Experimental Carcinogenesis Division, Istituto Superiore di Sanità, Rome, Italy

  • Rita Pepponi,

    Affiliation Department of Drug Research and Evaluation, Central Nervous System Pharmacology Division, Istituto Superiore di Sanità, Rome, Italy

  • Antonella Pèzzola,

    Affiliation Department of Drug Research and Evaluation, Central Nervous System Pharmacology Division, Istituto Superiore di Sanità, Rome, Italy

  • Patrizia Popoli,

    Affiliation Department of Drug Research and Evaluation, Central Nervous System Pharmacology Division, Istituto Superiore di Sanità, Rome, Italy

  • Margherita Bignami

    bignami@iss.it

    Affiliation Department of Environment and Primary Prevention, Experimental Carcinogenesis Division, Istituto Superiore di Sanità, Rome, Italy

A Role for Oxidized DNA Precursors in Huntington's Disease–Like Striatal Neurodegeneration

  • Gabriele De Luca, 
  • Maria Teresa Russo, 
  • Paolo Degan, 
  • Cecilia Tiveron, 
  • Andrea Zijno, 
  • Ettore Meccia, 
  • Ilenia Ventura, 
  • Elisabetta Mattei, 
  • Yusaku Nakabeppu, 
  • Marco Crescenzi
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