SEQ_NAME START END STRAND FEATURE_NAME TXN_START TXN_END EXON_COUNT EXON_STARTS EXON_ENDS CDS_START CDS_END GENE_NAME ALIASES DESCRIPTION Ca19-mtDNA 18 3148 + caalfmr16 18 3148 1 18 3148 RRNL mtLsurRNA Mitochondrial ribosomal RNA of the large ribosomal subunit [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca19-mtDNA 3172 3242 + caalfmt18 3172 3242 1 3172 3242 TRNA Mitochondrial alanine tRNA [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 3275 4063 + caalfmp01 3275 4063 1 3275 4063 3275 4063 COX2 Subunit II of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; one of three mitochondrially-encoded subunits [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 4002 4072 + caalfmt19 4002 4072 1 4002 4072 TRNN Mitochondrial asparagine tRNA [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 4131 4571 + caalfmp02 4131 4571 1 4131 4571 4131 4571 NAD6 Subunit 6 of NADH:ubiquinone oxidoreductase (NADH:ubiquinone dehydrogenase), a multisubunit enzyme complex (complex I) of the mitochondrial inner membrane that catalyzes the first step in mitochondrial respiration [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca19-mtDNA 4571 5524 + caalfmp03 4571 5524 1 4571 5524 4571 5524 NAD1 Subunit 6 of NADH:ubiquinone oxidoreductase (NADH:ubiquinone dehydrogenase), a multisubunit enzyme complex (complex I) of the mitochondrial inner membrane that catalyzes the first step in mitochondrial respiration [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 9929 10738 - caalfmp04 9929 10738 1 10738 9929 9929 10738 COX3A Subunit III of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; identical to Cox3Bp; one of three mitochondrially-encoded subunits [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 10778 10849 + caalfmt20 10778 10849 1 10778 10849 TRNK1 Mitochondrial lysine tRNA, one of two lysine tRNAs encoded on the mitochondrial genome [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 11525 11606 + caalfmt21 11525 11606 1 11525 11606 TRNL1 Mitochondrial leucine tRNA, one of three leucine tRNAs encoded on the mitochondrial genome [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 11614 11696 + caalfmt22 11614 11696 1 11614 11696 TRNY1 Mitochondrial tyrosine tRNA, one of two tyrosine tRNAs encoded on the mitochondrial genome [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 11704 11774 + caalfmt23 11704 11774 1 11704 11774 TRNH1 Mitochondrial histidine tRNA, one of two histidine tRNAs encoded on the mitochondrial genome [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 11780 11852 + caalfmt24 11780 11852 1 11780 11852 TRNT1 Mitochondrial threonine tRNA, one of two threonine tRNAs encoded on the mitochondrial genome [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 11856 11926 + caalfmt25 11856 11926 1 11856 11926 TRNE1 Mitochondrial glutamate tRNA, one of two glutamate tRNAs encoded on the mitochondrial genome [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 12456 12731 - caalfmp05 12456 12731 1 12731 12456 12469 12699 ATP9 Subunit 9 of the F0 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca19-mtDNA 12739 12809 + caalfmt26 12739 12809 1 12739 12809 TRNI Mitochondrial isoleucine tRNA [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 12895 13709 - caalfmp06 12895 13709 1 13709 12895 12895 13635 ATP6 Subunit 6 of the F0 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca19-mtDNA 13731 13906 - caalfmp07 13731 13906 1 13906 13731 13760 13906 ATP8 Subunit 8 of the F0 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca19-mtDNA 13945 14017 + caalfmt27 13945 14017 1 13945 14017 TRNP Mitochondrial proline tRNA [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 14104 14174 + caalfmt28 14104 14174 1 14104 14174 TRNC Mitochondrial cysteine tRNA [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 14181 14251 + caalfmt29 14181 14251 1 14181 14251 TRNG Mitochondrial glycine tRNA [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 14771 20926 + caalfmp08 14771 20926 5 14771|16351|18012|19002|20445 15163|16674|18020|19389|20926 14771 20926 COX1 Subunit I of cytochrome c oxidase, which is the terminal member of the mitochondrial (mt) inner membrane electron transport chain; one of three mt-encoded subunits; alternatively spliced transcripts encode 4 putative splicing endonucleases [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca19-mtDNA 14771 16264 + CaalfMp08.1 14771 16264 1 14771 16264 14771 16264 Putative endonuclease encoded by the first exon and part of the first intron of the mitochondrial COX1 gene; C-terminus contains a LAGLIDADG domain found in intron-encoded endonucleases; conserved in fungal mitochondria Ca19-mtDNA 14771 17625 + CaalfMp08.2 14771 17625 2 14771|16351 15163|17625 14771 17625 Putative endonuclease encoded by the first two exons and part of the second intron of the mitochondrial COX1 gene; C-terminus contains a LAGLIDADG domain found in intron-encoded endonucleases; conserved in fungal mitochondria Ca19-mtDNA 14771 18980 + CaalfMp08.3 14771 18980 3 14771|16351|18012 15163|16674|18980 14771 18980 Putative endonuclease encoded by the first three exons and part of the third intron of the mitochondrial COX1 gene; C-terminus contains a LAGLIDADG domain found in intron-encoded endonucleases; conserved in fungal mitochondria Ca19-mtDNA 14771 20120 + CaalfMp08.4 14771 20120 4 14771|16351|18012|19002 15163|16674|18020|20120 14771 20120 Putative endonuclease encoded by the first four exons and part of the fourth intron of the mitochondrial COX1 gene; C-terminus contains a LAGLIDADG domain found in intron-encoded endonucleases; conserved in fungal mitochondria Ca19-mtDNA 21066 21136 + caalfmt30 21066 21136 1 21066 21136 TRNR1 Mitochondrial arginine tRNA, one of two arginine tRNAs encoded on the mitochondrial genome [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 21155 21225 + caalfmt31 21155 21225 1 21155 21225 TRNV Mitochondrial valine tRNA [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 21228 21298 + caalfmt32 21228 21298 1 21228 21298 TRNW Mitochondrial tryptophan tRNA [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 21299 21369 + caalfmt33 21299 21369 1 21299 21369 TRNF Mitochondrial phenylalanine tRNA [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 21408 21478 + caalfmt34 21408 21478 1 21408 21478 TRNR2 Mitochondrial arginine tRNA, one of two arginine tRNAs encoded on the mitochondrial genome [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 21422 22849 + caalfmp09 21422 22849 1 21422 22849 21422 22849 NAD2 Subunit 2 of NADH:ubiquinone oxidoreductase (NADH:ubiquinone dehydrogenase), a multisubunit enzyme complex (complex I) of the mitochondrial inner membrane that catalyzes the first step in mitochondrial respiration [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 22849 23238 + caalfmp10 22849 23238 1 22849 23238 22849 23238 NAD3 Subunit 3 of NADH:ubiquinone oxidoreductase (NADH:ubiquinone dehydrogenase), a multisubunit enzyme complex (complex I) of the mitochondrial inner membrane that catalyzes the first step in mitochondrial respiration [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 23288 23498 + ntar_1 23288 23498 1 23288 23498 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca19-mtDNA 23997 26808 + caalfmp11 23997 26808 3 23997|25695|26074 24389|25730|26808 23997 26808 COB Cytochrome b, mitochondrially encoded subunit of the ubiquinol-cytochrome c reductase complex (complex III) that catalyzes a step in the respiratory chain of the mitochondrial inner membrane [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca19-mtDNA 23997 25434 + caalfmp11.1 23997 25434 1 23997 25434 23997 25434 Putative endonuclease encoded by the first exon and part of the first intron of the mitochondrial COB gene; C-terminus contains a GIY-YIG domain found in intron-encoded endonucleases; conserved in fungal mitochondria [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca19-mtDNA 26935 27005 + caalfmt35 26935 27005 1 26935 27005 TRNM1 Mitochondrial methionine tRNA, one of two methionine tRNAs encoded on the mitochondrial genome [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 27022 28483 + caalfmr17 27022 28483 1 27022 28483 RRNS Mitochondrial ribosomal RNA of the small ribosomal subunit [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 29570 29824 + caalfmp12 29570 29824 1 29570 29824 29570 29824 NAD4L Subunit 4L of NADH:ubiquinone oxidoreductase (NADH:ubiquinone dehydrogenase), a multisubunit enzyme complex (complex I) of the mitochondrial inner membrane that catalyzes the first step in mitochondrial respiration [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 29824 31482 + caalfmp13 29824 31482 1 29824 31482 29824 31482 NAD5 Subunit 5 of NADH:ubiquinone oxidoreductase (NADH:ubiquinone dehydrogenase), a multisubunit enzyme complex (complex I) of the mitochondrial inner membrane that catalyzes the first step in mitochondrial respiration [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 31492 31563 + caalfmt36 31492 31563 1 31492 31563 TRNQ Mitochondrial glutamine tRNA [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 31570 31641 + caalfmt37 31570 31641 1 31570 31641 TRND Mitochondrial aspartate tRNA [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 31646 31729 + caalfmt38 31646 31729 1 31646 31729 TRNS1 Mitochondrial serine tRNA [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 31925 32005 + caalfmt39 31925 32005 1 31925 32005 TRNS2 Mitochondrial serine tRNA, one of two serine tRNAs encoded on the mitochondrial genome [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 32015 32088 + caalfmt40 32015 32088 1 32015 32088 TRNL2 Mitochondrial leucine tRNA, one of three leucine tRNAs encoded on the mitochondrial genome [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 32120 33514 + caalfmp14 32120 33514 1 32120 33514 32120 33514 NAD4 Subunit 4 of NADH:ubiquinone oxidoreductase (NADH:ubiquinone dehydrogenase), a multisubunit enzyme complex (complex I) of the mitochondrial inner membrane that catalyzes the first step in mitochondrial respiration [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 33486 33557 + caalfmt41 33486 33557 1 33486 33557 TRNM2 Mitochondrial methionine tRNA, one of two methionine tRNAs encoded on the mitochondrial genome [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 34034 34104 + caalfmt42 34034 34104 1 34034 34104 TRNE2 Mitochondrial glutamate tRNA, one of two glutamate tRNAs encoded on the mitochondrial genome [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 34108 34180 + caalfmt43 34108 34180 1 34108 34180 TRNT2 Mitochondrial threonine tRNA, one of two threonine tRNAs encoded on the mitochondrial genome [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 34186 34256 + caalfmt44 34186 34256 1 34186 34256 TRNH2 Mitochondrial histidine tRNA, one of two histidine tRNAs encoded on the mitochondrial genome [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 34264 34346 + caalfmt45 34264 34346 1 34264 34346 TRNY2 Mitochondrial tyrosine tRNA, one of two tyrosine tRNAs encoded on the mitochondrial genome [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 34354 34435 + caalfmt46 34354 34435 1 34354 34435 TRNL3 Mitochondrial leucine tRNA, one of three leucine tRNAs encoded on the mitochondrial genome [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 35111 35182 + caalfmt47 35111 35182 1 35111 35182 TRNK2 Mitochondrial lysine tRNA, one of two lysine tRNAs encoded on the mitochondrial genome [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca19-mtDNA 35222 36031 + caalfmp15 35222 36031 1 35222 36031 35222 36031 COX3B Subunit III of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; identical to Cox3Ap; one of three mitochondrially-encoded subunits [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1349 1602 - ntar_2 1349 1602 1 1602 1349 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1645 2326 + ntar_3 1645 2326 1 1645 2326 2051 2242 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2563 2943 + ntar_4 2563 2943 1 2563 2943 2571 2810 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2958 3663 - ntar_5 2958 3663 1 3663 2958 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 3934 4136 - ntar_6 3934 4136 1 4136 3934 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 4059 4397 + orf19.6115 4059 4397 1 4059 4397 4059 4397 orf19.13534|IPF21113.1|IPF27828.1|CaO19.11880|CaO19.4402|CaO19.6115|CaO19.13534 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 4409 5290 - orf19.6114 4409 5290 1 5290 4409 4720 4409 orf19.13533|IPF21135.1|IPF27840.1|orf6.6227|CaO19.13533|CaO19.6114 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr1 8597 8908 - orf19.6113 8597 8908 1 8908 8597 8908 8597 orf19.13532|IPF21132.1|IPF10769.1|orf6.6228|CaO19.6113|CaO19.13532 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 9972 10135 - ntar_7 9972 10135 1 10135 9972 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 10718 11485 + orf19.6112 10718 11485 1 10718 11485 10718 11485 CTA2 orf19.13531|IPF21081.1|IPF10779.1|orf6.6229|CA3851|CTA21|TLO3|CTA210|CaO19.6112|CaO19.13531 Putative transcriptional activator, activates transcription in 1-hybrid assay in S. cerevisiae; downregulated by Efg1p; member of a family of telomere-proximal genes; transcription is positively regulated by Tbf1p [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 11648 11995 - orf19.6110 11648 11995 1 11995 11648 11995 11648 orf19.13529|IPF21110.1|IPF10780.2|Contig4-1846_0001|orf6.6231|CaO19.13529|CaO19.6110 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 12141 13744 + orf19.6109 12141 13744 1 12141 13744 12157 13701 TUP1 orf19.13528|IPF21053.1|IPF4657.2|orf6.6232|CA3852|CaO19.6109|CaO19.13528 Transcriptional corepressor; represses filamentous growth, regulates phase switching, roles in germ tube induction, farnesol response; has C-terminal WD40 repeats; farnesol upregulated in biofilm; in repression pathways with Nrg1p, Rfg1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr1 13763 15003 + orf19.6105 13763 15003 2 13763|13868 13816|15003 13778 14917 MVD orf19.13524|MVD1|IPF4647.2|IPF4652.1|Contig4-2342_0002|orf6.6236|CA3853|MVD1.3 Mevalonate diphosphate decarboxylase; functional homolog of S. cerevisiae Erg19p; possible drug target; transcriptionally regulated by carbon source, yeast-hyphal switch, growth phase, antifungals; gene has intron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 14809 15761 - orf19.6102 14809 15761 1 15761 14809 15761 14910 orf19.13521|IPF21080.1|IPF4649.1|Contig4-2342_0004|orf6.6239|CA3854|CaO19.6102|CST6|CaO19.13521|IPF4649 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 15595 17171 + orf19.6103 15595 17171 1 15595 17171 16104 16631 orf19.13522|IPF21098.1|IPF4645.1|Contig4-2342_0005|orf6.6238|CA3855|CaO19.6103|CaO19.13522|IPF4645 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=D scenario_last_exon=D] Ca21chr1 16324 17328 - orf19.6100 16324 17328 1 17328 16324 17328 16600 orf19.13519|CRD1|IPF21085.1|IPF4641.1|Contig4-2342_0007|orf6.6241|CA3856|CaO19.6100|CaO19.13519|IPF4641 Protein not essential for viability; similar to S. cerevisiae Crd1p, which is cardiolipin synthase; transcription is upregulated in clinical isolates from HIV+ patients with oral candidiasis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 17330 19131 + orf19.6099 17330 19131 1 17330 19131 17338 18960 CCT8 orf19.13518|IPF21047.1|IPF4639.1|orf6.6242|CA3857|CaO19.6099|CaO19.13518 Essential protein similar to chaperonin complex subunit 8; involved in hyphal morphogenesis, particularly starvation-induced; production in S. cerevisiae inhibits Ras2p-mediated pathways (including pseudohyphal); CCT1 and TRP1 genes overlap [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 18732 19628 - orf19.6096 18732 19628 1 19628 18732 19628 18948 TRP1 IPF21091.1|IPF4635.2|Contig4-2998_0001|orf6.6245|CA3858|CaO19.6096|CaO19.13515 Phosphoribosylanthranilate isomerase; enzyme of tryptophan biosynthesis; expected to be unifunctional, unlike trifunctional enzyme of some other fungi; complements E. coli trpC or S. cerevisiae trp1 mutant; CCT1 and TRP1 genes overlap [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 19615 22020 - orf19.6094 19615 22020 1 22020 19615 21714 19615 orf19.13513|IPF21026.1|IPF4632.2|Contig4-2998_0005|orf6.6247|CA3859|VPS53|CaO19.6094|CaO19.13513|IPF4632 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 22143 25375 + orf19.6092 22143 25375 1 22143 25375 22270 25326 KEL1 orf19.13511|IPF21143.1|IPF4628.1|Contig4-2998_0008|orf6.6249|CA3860|CaO19.13511|KEL2|CaO19.6092 Protein containing a Kelch repeat domain, similar to S. cerevisiae Kel1p; not required for adherence to buccal epithelial cells or virulence in mouse systemic infection; null mutant colonies exhibit slightly decreased filamentation ratio [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 25327 27656 - orf19.6091 25327 27656 1 27656 25327 27249 25381 RIM8 orf19.13510|PRR1|RIN|IPF21039.1|IPF4622.1|Contig4-2998_0009|orf6.6250|CA3861|CaO19.6091|CaO19.13510 Protein involved in the pH response pathway; required for activation of the transcription factor Rim101p and for alkaline pH-induced hyphal growth; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 28166 29497 - orf19.6090 28166 29497 1 29497 28166 29488 28286 orf19.13509|IPF21063.1|IPF4616.2|Contig4-2998_0012|orf6.6252|CA3862|CaO19.6090|NSR1|CaO19.13509 Predicted ORF in Assemblies 19, 20 and 21; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 29679 31570 + orf19.6086 29679 31570 1 29679 31570 29804 31543 LEU4 orf19.13505|IPF21043.1|IPF4611.1|LEU41|Contig4-2998_0014|orf6.6255|CA3863|CaO19.6086|CaO19.13505 Putative 2-isopropylmalalate synthase; regulated by Nrg1p, Mig1p, Tup1p, Gcn4p; upregulated in the presence of human whole blood or polymorphonuclear (PMN) cells; macrophage/pseudohyphal-repressed after 16h; fungal-specific [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 31243 31503 - ntar_8 31243 31503 1 31503 31243 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 31822 32677 + orf19.6085 31822 32677 1 31822 32677 31842 32444 RPL16A orf19.13504|IPF21087.1|IPF4609.1|Contig4-2998_0015|orf6.6256|CA3864|CaO19.13504|RPL16|CaO19.6085 Protein similar to S. cerevisiae ribosomal protein Rpl16Ap; transposon mutation affects filamentous growth; genes encoding cytoplasmic ribosomal subunits are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 32680 33318 - orf19.6084 32680 33318 1 33318 32680 33318 32680 orf19.13503|IPF21095.1|IPF4608.1|Contig4-2998_0016|orf6.6257|CA3865|CaO19.6084|CaO19.13503|IPF4608 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 33954 34446 - orf19.6083 33954 34446 1 34446 33954 34446 34099 orf19.13502|IPF21127.1|IPF4607.1|Contig4-2998_0017|orf6.6258|CaO19.13502|CaO19.6083 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 34525 35735 - orf19.6082 34525 35735 1 35735 34525 35679 34525 orf19.13501|IPF21065.1|IPF4606.1|Contig4-2998_0019|orf6.6259|CA3866|CaO19.13501|GSF2|CaO19.6082|IPF4606 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 37723 39612 + orf19.6081 37723 39612 1 37723 39612 37852 39486 PHR2 orf19.13500|orf6.6260|IPF4604.2|IPF14612.3|Contig4-2998_0022|orf6.1067|CA3867|CaO19.6081 Glycosidase; role in cell wall structure; may act on beta-1,3-glucan prior to beta-1,6-glucan linkage; role in vaginal but not systemic virulence (low pH, not neutral); low pH, high iron, fluconazole induced; Rim101p-downregulated at pH 8 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 40208 41898 - orf19.6080 40208 41898 1 41898 40208 41771 40485 orf19.13499|IPF21062.1|IPF14615.1|Contig4-2160_0002|orf6.1066|CA0287|BFA1|CaO19.6080|IPF14615 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 42101 42173 - tt(agu)6 42101 42173 1 42173 42101 tT(AGU)6.2 tRNA-Thr predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 42606 43505 + orf19.6079 42606 43505 1 42606 43505 42606 43505 IPF14618|IPF14618.2|Contig4-2960_0013|orf6.1065|orf6.1757|CA0286|CaO19.6079|IPF14618.1 Predicted ORF in retrotransposon Tca8 with similarity to the Gag region encoding nucleocapsid-like protein; transcription is downregulated in response to treatment with ciclopirox olamine; filament induced; regulated by Rfg1p, Tup1p [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 43483 43680 - orf19.6078.1 43483 43680 1 43680 43483 43677 43483 RFC52 IPF14619.2 ORF Predicted by Annotation Working Group; periodic mRNA expression, peak at cell-cycle G1/S phase [label_first_exon=CGD label_last_exon=CGD orf_changed=true scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 43804 45765 + orf19.6078 43804 45765 1 43804 45765 43804 45765 POL93 IPF17652.3|Contig4-2396_0002|Contig4-2396_0003|Contig4-2960_0011|orf6.241|orf6.1756|CA0037|CaO19.6078|IPF17652.2 Predicted ORF in retrotransposon Tca8 with similarity to the Pol region of retrotransposons encoding reverse transcriptase, protease and integrase; downregulated in response to ciclopirox olamine; induced upon biofilm formation [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 46149 46431 + ntar_9 46149 46431 1 46149 46431 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 46564 48414 + orf19.6077 46564 48414 1 46564 48414 46804 48360 orf19.13498|IPF8369.2|IPF27822.1|Contig4-2396_0004|orf6.7621|CA4936|CaO19.13498|CaO19.6077|IPF8369 Predicted ORF in Assemblies 19, 20 and 21; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 48471 49335 + orf19.6076 48471 49335 1 48471 49335 48514 49299 orf19.13497|IPF21082.1|IPF8370.1|Contig4-2396_0005|orf6.7620|CA4935|CaO19.6076|VPS29|CaO19.13497 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 49152 49890 - orf19.6075 49152 49890 1 49890 49152 49844 49296 orf19.13496|IPF21103.1|IPF8371.1|Contig4-2396_0006|orf6.7619|CA4934|CaO19.13496|CDC36|CaO19.6075 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 49969 51091 + orf19.6074 49969 51091 1 49969 51091 49998 50744 HBR1 orf19.13495|IPF21079.1|IPF8372.1|orf6.7618|CA4933|FAP7|CaO19.6074|CaO19.13495|IPF8372 Essential protein involved in regulation of MTL gene expression; hemoglobin-regulated inhibitor of white-opaque switching, which may affect survival in host; activator of MTLalpha1 and MTLalpha2; transcription is activated by hemoglobin [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 50735 51759 - orf19.6073 50735 51759 1 51759 50735 51682 50807 HMX1 orf19.13494|orf6.7617|YLR205C|IPF21077.1|IPF8374.1|Contig4-2523_0009|CA4932|CaO19.13494|CaO19.6073|IPF8374 Heme oxygenase; acts in utilization of hemin iron; gene transcriptionally activated by heat, low iron, or hemin; negatively regulated by Efg1p; expression greater in low iron; upregulated by Rim101p at pH 8 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 53100 55389 + orf19.6072 53100 55389 1 53100 55389 53100 54443 orf19.13493|IPF21058.1|IPF8378.2|Contig4-2523_0007|orf6.7616|CA4931|CaO19.6072|CaO19.13493|IPF8378 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 53819 54169 - ntar_10 53819 54169 1 54169 53819 54169 53891 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 54667 57099 - orf19.6071 54667 57099 1 57099 54667 57075 54838 orf19.13492|IPF21019.1|IPF8381.2|Contig4-2523_0004|Contig4-2523_0005|orf6.7615|CA4930|MDM20|CaO19.6071|CaO19.13492|IPF8381 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 57822 58215 + ntar_11 57822 58215 1 57822 58215 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 59271 62570 + orf19.6070 59271 62570 1 59271 62570 59350 62553 ENA2 orf19.13491|orf6.7614|ENA22|IPF21137.1|IPF1398.2|Contig4-2977_0027|Contig4-2977_0028|CA4929|CaO19.6070|CaO19.13491 Protein described as sodium transporter; transcription is upregulated in response to ciclopirox olamine; alkaline upregulated by Rim101p; repressed upon high-level peroxide stress; upregulated in oral candidiasis clinical isolates [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 63101 64635 + orf19.6068 63101 64635 1 63101 64635 63203 64351 SVF1 orf19.13489|IPF21067.1|IPF1399.2|Contig4-2977_0025|orf6.7612|CA4928|CaO19.13489|CaO19.6068|IPF1399 Predicted ORF in Assemblies 19, 20 and 21; fluconazole-induced; regulated by Gcn4p; repressed in response to amino acid starvation (3-aminotriazole treatment); fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 64593 66481 - orf19.6066 64593 66481 1 66481 64593 66325 64697 orf19.13487|IPF21050.1|IPF1401.2|Contig4-2977_0023|orf6.7610|CA4927|CaO19.13487|CaO19.6066|IPF1401 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 67814 68859 + orf19.6065 67814 68859 1 67814 68859 67844 68815 orf19.13486|orf6.7609|IPF21071.1|IPF1404.1|Contig4-2977_0018|CA4926|CaO19.13486|CaO19.6065|IPF1404 Gene transcription regulated by Mig1p and Tup1p; amphotericin B, caspofungin repressed; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 69149 70919 + orf19.6064 69149 70919 1 69149 70919 69227 70903 orf19.13485|IPF18155.2|IPF1408.1|Contig4-2977_0013|Contig4-2977_0014|orf6.7608|CA4925|CaO19.13485|ATG18|CaO19.6064|IPF1408 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 71042 72755 + orf19.6063 71042 72755 2 71042|71159 71081|72755 71069 72582 UBP6 orf19.13484|IPF21056.1|IPF1412.1|Contig4-2977_0011|orf6.7607|UBP6.3f|CA4924|CaO19.13484|CaO19.6063|UBP6.3 Predicted ORF in Assemblies 19, 20 and 21; oxidative stress-induced via Cap1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 72580 73356 - orf19.6062.3 72580 73356 2 73356|73092 73183|72580 73284 72742 IPF21126.1|IPF1413.1|Contig4-2977_0010|CA4923|IPF1413.3f|IPF1413.3 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 73506 74022 + orf19.6062 73506 74022 1 73506 74022 73581 73901 orf19.13483|IPF21130.1|IPF1415.1|Contig4-2977_0005|orf6.7606|CA4922|CaO19.13483|CaO19.6062|IPF1415 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 73934 75420 - orf19.6061 73934 75420 1 75420 73934 75382 74057 orf19.13482|IPF21059.1|IPF1416.1|Contig4-2977_0004|orf6.7605|CA4921|FMP30|CaO19.13482|CaO19.6061|IPF1416 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 75444 77854 - orf19.6060 75444 77854 1 77854 75444 77829 75574 GCN20 orf19.13481|IPF21021.1|IPF1420.1|Contig4-2977_0003|orf6.7604|CA4920|CaO19.6060|CaO19.13481 YEF3-subfamily ABC family protein, predicted not to be a transporter [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 77931 78445 - orf19.6059 77931 78445 1 78445 77931 78368 78009 TTR1 orf19.13480|IPF21120.1|IPF1421.1|Contig4-2977_0001|orf6.7603|CA4919|GRX2|CaO19.13480|TTR11|CaO19.6059 Putative glutaredoxin; described as a glutathione reductase; upregulated in the presence of human neutrophils, and upon benomyl treatment; alkaline downregulated; regulated by Gcn2p and Gcn4p; required for virulence in mouse model [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 78567 79675 - orf19.6058 78567 79675 1 79675 78567 79670 78642 GLO1 orf19.13479|IPF21068.1|IPF1422.1|orf6.7602|CA4918|CaO19.13479|CaO19.6058 Predicted ORF in Assemblies 19, 20 and 21; oxidative stress-induced via Cap1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 79990 81168 + orf19.6057 79990 81168 1 79990 81168 80125 81054 orf19.13478|IPF21074.1|IPF1424.1|Contig4-3053_0035|orf6.7601|CA4917|CaO19.6057|ECM31|CaO19.13478 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 81203 82050 + orf19.6056 81203 82050 1 81203 82050 81234 81902 orf19.13477|IPF21093.1|IPF1425.1|Contig4-3053_0032|orf6.7600|CA4916|CaO19.13477|CaO19.6056|IPF1425 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 82003 84730 - orf19.6055 82003 84730 1 84730 82003 84559 82118 orf19.13476|IPF21013.1|IPF1427.1|Contig4-3053_0030|orf6.7599|CA4915|BUL3|CaO19.13476|CaO19.6055|IPF1427 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 85022 87395 - orf19.6054 85022 87395 1 87395 85022 87249 85081 orf19.13475|IPF21022.1|IPF1428.2|Contig4-3053_0028|orf6.7598|CA4914|CaO19.6054|BUL2|CaO19.13475|IPF1428 Predicted ORF in Assemblies 19, 20 and 21; decreased transcription is observed in an azole-resistant strain that overexpresses MDR1 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 87773 89905 + orf19.6053 87773 89905 1 87773 89905 87901 89811 CIS2 orf19.13474|IPF21037.1|IPF1431.1|Contig4-3053_0023|orf6.7597|CA4913|CaO19.6053|ECM38|CaO19.13474 Putative role in regulation of biogenesis of the cell wall; upregulated in biofilm; Gcn4p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 90059 91373 + orf19.6052 90059 91373 1 90059 91373 90100 91272 CNS1 orf19.13473|IPF21066.1|IPF1432.1|Contig4-3053_0020|orf6.7596|CA4912|CaO19.13473|CaO19.6052 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to radicicol [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 90779 93779 - orf19.6049 90779 93779 1 93779 90779 93695 91311 orf19.13470|IPF21018.1|IPF1435.1|Contig4-3053_0017|orf6.7593|CA4911|CaO19.13470|CaO19.6049|IPF1435 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 93903 94925 + orf19.6048 93903 94925 1 93903 94925 93971 94900 orf19.13469|IPF21073.1|IPF1437.1|Contig4-3053_0016|orf6.7592|CA4910|CaO19.6048|CaO19.13469|IPF1437 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 95125 96686 + orf19.6047 95125 96686 1 95125 96686 95215 96495 TUF1 orf19.13468|IPF21060.1|IPF1439.1|Contig4-3053_0014|orf6.7591|CA4909|CaO19.6047|CaO19.13468 Putative translation elongation factor; macrophage/pseudohyphal-induced; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 96757 101461 + orf19.6046 96757 101461 1 96757 101461 96817 101424 APC1 orf19.13467|IPF21111.1|IPF1445.2|Contig4-3053_0013|orf6.7590|CA4908|CaO19.6046|CaO19.13467|IPF1445 Predicted ORF in Assemblies 19, 20 and 21; essential for growth; periodic mRNA expression, peak at cell-cycle S/G2 phase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 101691 103644 + orf19.6045 101691 103644 1 101691 103644 101752 103524 orf19.13466|IPF21041.1|IPF1448.1|Contig4-3053_0005|orf6.7589|CA4907|CaO19.6045|PSD1|CaO19.13466 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 103756 104981 + orf19.6044 103756 104981 1 103756 104981 103869 104810 MOB2 orf19.13465|IPF21075.1|IPF1449.1|Contig4-3053_0003|orf6.7588|CA4906|CaO19.13465|CaO19.6044 Mob1/phocein domain protein of RAM signaling network of cell wall integrity; role in cell separation, cortical actin polarization; required for hyphal growth; interacts with Cbk1p; mRNA binds to She3p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 104840 105092 - ntar_12 104840 105092 1 105092 104840 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 105159 107109 + orf19.6043 105159 107109 1 105159 107109 105180 106925 orf19.13464|IPF21048.1|IPF1451.1|Contig4-3053_0001|orf6.7587|CA4905|CaO19.13464|CaO19.6043|DLD1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 106976 111148 - orf19.6041 106976 111148 1 111148 106976 111028 107126 RPO41 orf19.13462|IPF21121.1|IPF1453.2|Contig4-3053_0037|orf6.7585|CA4904|CaO19.6041|CaO19.13462 Predicted ORF in Assemblies 19, 20 and 21; downregulated during core stress response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 111335 112500 - orf19.6040 111335 112500 1 112500 111335 112252 111572 SNF7 orf19.13461|IPF21090.1|IPF1454.1|Contig4-2972_0022|orf6.7584|VPS32|CA4903|CaO19.13461|CaO19.6040 Protein involved in echinocandin, azole sensitivity; role in proteolytic activation of Rim101p; separable roles in RIM101 pathway and in transport from MVB to vacuole; similar to S. cerevisiae Snf7p component of ESCRT III complex [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 112753 113872 - orf19.6039 112753 113872 1 113872 112753 113802 112789 orf19.13460|IPF21070.1|IPF1455.1|Contig4-2972_0019|orf6.7583|CA4902|CaO19.6039|SED5|CaO19.13460 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 114006 115966 - orf19.6038 114006 115966 1 115966 114006 115879 114128 UGA32|orf19.13459|IPF21042.1|IPF1457.1|Contig4-2972_0013|Contig4-2972_0017|orf6.7582|CA4901|CaO19.6038|CaO19.13459|IPF1457 Predicted zinc-finger protein of unknown function; has similarity to S. cerevisiae Uga3p, which is a transcription factor involved in the regulation of gamma-aminobutyrate metabolism genes [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 114049 114377 + ntar_13 114049 114377 1 114049 114377 114049 114270 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 117088 119522 + orf19.6037 117088 119522 1 117088 119522 117320 119443 ASM3 orf19.13458|orf6.7581|IPF21027.1|IPF1459.1|Contig4-2972_0011|CA4900|IFP2|CaO19.13458|CaO19.6037 Putative secreted acid sphingomyelin phosphodiesterase; induced upon biofilm formation; possible Kex2p substrate; increased transcription is observed in an azole-resistant strain that overexpresses MDR1 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 119713 122873 + orf19.6036 119713 122873 1 119713 122873 119768 122809 RIC1 orf19.13457|IPF21148.1|IPF1460.1|Contig4-2972_0009|orf6.7580|CA4899|CaO19.6036|CaO19.13457|IPF1460 Protein not essential for viability; similar to S. cerevisiae Ric1p, which is a guanyl-nucleotide exchange factor [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 122901 123591 + orf19.6035 122901 123591 1 122901 123591 123067 123432 orf19.13456|IPF21108.1|IPF1461.1|Contig4-2972_0006|orf6.7579|CA4898|CaO19.13456|CaO19.6035|IPF1461 Predicted ORF in Assemblies 19, 20 and 21; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 123634 125678 - orf19.6034 123634 125678 3 125678|125370|125170 125586|125335|123634 125597 123869 TUB2 orf19.13455|IPF21061.1|IPF1463.1|Contig4-2972_0005|orf6.7578|CA4897|TUB2.3 Beta-tubulin; functional homolog of ScTub2p; hyphal-induced; fluconazole-induced; gene has two introns; overproduction causes inviability in S. cerevisiae; slow growth, increased white-to opaque switching in ectopic expression strains [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=F] Ca21chr1 126521 126779 + tp(ugg)3 126521 126779 2 126521|126577 126556|126779 126540 126691 tP(UGG)3.2 tRNA-Pro predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr1 126663 129074 - orf19.6033 126663 129074 1 129074 126663 128619 126790 CMP1 orf19.13454|CNA|IPF18159.2|IPF1465.2|Contig4-2972_0002|orf6.3161|orf6.7577|CA1587|CNA1|CaO19.6033|CMP2 Catalytic subunit of calcineurin (Ca[2+]-calmodulin-regulated S/T protein phosphatase); required for wild-type virulence, resistance to high pH, Na(+), Li(+), Mn(2+), and fluconazole tolerance; micafungin is fungicidal to null mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 129157 131047 - orf19.6032 129157 131047 1 131047 129157 130680 129259 SPE1 orf19.13453|ODC|ODC1|IPF21057.1|IPF1466.2|Contig4-2972_0001|orf6.3160|CA1586|CaO19.13453|CaO19.6032 Ornithine decarboxylase; enzyme of polyamine biosynthesis; not essential for viability; functionally complements polyamine auxotrophy of S. cerevisiae spe1 mutant; upregulated in biofilm; downregulated upon adherence to polystyrene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 131235 134123 - orf19.6031 131235 134123 1 134123 131235 133937 131412 orf19.13452|IPF21016.1|IPF15825.2|Contig4-3066_0007|orf6.3159|CA1585|CaO19.13452|VPS27|CaO19.6031 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 134226 135337 + orf19.6030 134226 135337 1 134226 135337 134256 134915 orf19.13451|IPF21086.1|IPF15824.2|orf6.3158|CA1584|CaO19.6030|CaO19.13451|IPF15824 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 135327 136867 - orf19.6029 135327 136867 1 136867 135327 136438 135656 ROT1 orf19.13450|IPF21084.1|IPF18655.1|Contig4-2871_0003|orf6.3157|CA1583|CaO19.6029 Similar to S. cerevisiae Rot1p, which is involved in cell wall 1,6-beta-glucan biosynthesis; has predicted transmembrane region [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 137537 137940 + ntar_14 137537 137940 1 137537 137940 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 138517 139742 + ntar_15 138517 139742 1 138517 139742 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 138579 140936 - orf19.6028 138579 140936 1 140936 138579 140936 138579 HGC1 orf19.13449|IPF7912.2|IPF15332.2|CLN21|Contig4-2280_0001|orf6.1969|orf6.3156|CA1582|CLN3|CaO19.6028 Hypha-specific G1 cyclin-related protein involved in regulation of hyphal morphogenesis; Cdc28p-Hgc1p maintains Cdc11p S394 phosphorylation during hyphal growth; required for virulence in mouse model; regulated by Nrg1p, Tup1p, farnesol [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr1 147577 148496 - ntar_16 147577 148496 1 148496 147577 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 150512 152082 + orf19.6027 150512 152082 1 150512 152082 150614 151714 orf19.13448|IPF18867.2|IPF7903.2|Contig4-2833_0014|orf6.1968|orf6.3931|CA2155|CaO19.6027|IPF7903 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 154292 155353 - orf19.6026 154292 155353 1 155353 154292 155291 154638 ERG2 orf19.13447|IPF21092.1|IPF7901.2|Contig4-2833_0009|orf6.3930|CA2154|CaO19.6026|CaO19.13447 C-8 sterol isomerase; enzyme of ergosterol biosynthesis pathway; converts fecosterol to episterol; mutant is hypersensitive to multiple drugs; ketoconazole-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 155448 156497 + orf19.6025 155448 156497 1 155448 156497 155448 156329 orf19.13446|IPF21076.1|IPF7900.1|Contig4-2833_0008|orf6.3929|CA2153|CaO19.13446|CaO19.6025|IPF7900 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 156648 158089 + orf19.6024 156648 158089 1 156648 158089 156648 157694 orf19.13445|IPF21069.1|IPF7899.1|Contig4-2833_0005|orf6.3928|CA2152|CaO19.6024|CaO19.13445|IPF7899 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 158685 160659 + orf19.6023 158685 160659 1 158685 160659 158729 160528 orf19.13444|IPF21040.1|IPF7898.2|Contig4-2833_0002|orf6.3927|CA2151|MTE4|CaO19.6023|CaO19.13444|ERC2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 160632 162970 - orf19.6022 160632 162970 1 162970 160632 162676 160946 orf19.13443|IPF21044.1|IPF19940.1|Contig4-2810_0001|Contig4-2810_0002|Contig4-2833_0019|orf6.3926|CA2150|CaO19.13443|CaO19.6022|IPF19940 Predicted ORF in Assemblies 19, 20 and 21; downregulated during core stress response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 166952 167956 + orf19.6021 166952 167956 1 166952 167956 167084 167830 IHD2 orf19.13442|orf6.3925|IPF21083.1|IPF10761.1|Contig4-2810_0012|CA2149|CaO19.6021|CaO19.13442|IPF10761 Transcriptionally regulated by iron and by yeast-hyphal switching; expression greater in low iron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 168387 169654 + orf19.6020 168387 169654 1 168387 169654 168540 169541 orf19.13441|IPF21072.1|IPF10762.1|Contig4-2810_0014|orf6.3924|CA2148|ATG3|CaO19.6020|AUT1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 169009 169878 - ntar_17 169009 169878 1 169878 169009 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 169978 172393 + orf19.6018 169978 172393 1 169978 172393 170165 172261 LRO1 orf19.13439|IPF19448.2|IPF10764.2|IPF18532.1|Contig4-2810_0017|orf6.3922|orf6.91|orf6.3923|CA6302|CA0012|orf19.6019|IPF19448.3f Predicted ORF in Assemblies 19, 20 and 21; nonessential; similar to S. cerevisiae Lro1p acyltransferase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 174466 176091 + orf19.6017 174466 176091 1 174466 176091 174466 176091 orf19.13438|IPF21049.1|IPF13839.1|Contig4-2810_0020|orf6.1429|CA0477|MCM1|CaO19.6017|CaO19.13438|IPF13839 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 176291 178544 + orf19.6016 176291 178544 1 176291 178544 176332 178482 orf19.13437|IPF13843.2|IPF5084.2|Contig4-2810_0023|orf6.1430|orf6.5096|CA0478|CaO19.6016|YAE8 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 178653 179423 + orf19.6014 178653 179423 1 178653 179423 178697 179314 RRS1 orf19.13435|IPF13845.2|IPF5085.1|orf6.1432|orf6.5094|CA2992|CaO19.6014 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 179760 180965 + orf19.6013 179760 180965 4 179760|179953|180136|180652 179877|180048|180565|180965 179830 180836 orf19.13434|IPF21106.1|IPF5088.1|orf6.5093|CA2991|IPF5088|IPF5088.3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 181338 185381 + orf19.6012 181338 185381 1 181338 185381 181410 185246 orf19.13433|IPF21122.1|IPF5092.2|orf6.5092|CA2990|CaO19.13433|CaO19.6012|IPF5092 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 185392 190232 - orf19.6011 185392 190232 5 190232|190018|189907|189700|189177 190094|189972|189786|189357|185392 190152 185514 SIN3 orf19.13432|orf6.5091|IPF21124.1|IPF5096.2|Contig4-2910_0015|orf19.6010.3|CA2988|CA2989|SIN3.exon3|SIN3.exon2|IPF5097.2 Protein similar to S. cerevisiae Sin3p (transcriptional corepressor involved in histone deacetylase recruitment); has paired amphipathic helix PAH1 domain; interacts with ScOpi1p, not CaOpi1p; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 190611 191471 + orf19.6010.1 190611 191471 2 190611|190841 190756|191471 190704 191162 RPB11 IPF21134.1|IPF5100.2|Contig4-2910_0010|CA2987|RPB11.3f|RPB11.3 ORF Predicted by Annotation Working Group; flucytosine induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 191231 193726 - orf19.6010 191231 193726 1 193726 191231 193411 191450 CDC5 orf19.13431|IPF21034.1|IPF5102.1|Contig4-2910_0009|orf6.5090|CA2986|CaO19.13431|CaO19.6010 Polo-like kinase; probably essential for viability; depletion causes defects in spindle elongation and causes Cdc35p-dependent filamentation; member of conserved Mcm1p regulon; virulence-group-correlated expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 194192 198013 - orf19.6009 194192 198013 1 198013 194192 197804 194682 SET1 orf19.13430|IPF21139.1|IPF5105.1|Contig4-2910_0006|Contig4-2910_0007|orf6.5089|CA2985|CaO19.6009|CaO19.13430 Lysine histone methyltransferase; methylates K4 of histone H3; has a role in regulation of white-opaque switching, epithelial cell adhesion, agar-embedded filamentation, and virulence in mouse; unique N-terminus is immunogenic in human [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 198123 198861 + orf19.6008.3 198123 198861 2 198123|198358 198290|198861 198227 198752 IPF21109.1|IPF5107.1|Contig4-2910_0004|CA6228|IPF5107 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 198878 199339 + orf19.6008.4 198878 199339 1 198878 199339 198957 199226 Predicted ORF in Assembly 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 199234 202318 - orf19.3288 199234 202318 1 202318 199234 202255 199322 NMA111 orf19.10798|IPF23911.1|IPF12606.1|orf6.1778|CA0693|orf19.6008.1|orf19.3288.1|IPF12606.5eoc Predicted ORF in Assemblies 19, 20 and 21; macrophage-induced gene; downregulated in core stress response; fungal-specific (no human or murine homolog); merged with orf19.3288.1 in Assembly 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 202454 203679 - orf19.3289 202454 203679 1 203679 202454 203629 202538 orf19.10799|IPF23943.1|IPF12603.1|Contig4-2295_0001|orf6.1779|CA0694|CaO19.10799|ORC6|CaO19.3289|IPF12603 Phosphorylated protein of unknown function; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 203877 204529 + orf19.3290 203877 204529 1 203877 204529 203952 204422 orf19.10800|IPF23959.1|IPF12601.1|Contig4-2295_0003|orf6.1780|CA0695|CaO19.3290|CaO19.10800|IPF12601 Predicted ORF in Assemblies 19, 20 and 21; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 204992 205064 + ta(agc)4 204992 205064 1 204992 205064 tA(AGC)4.2 tRNA-Ala predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 205101 206414 + orf19.3291 205101 206414 1 205101 206414 205272 206291 HMT1 orf19.10801|IPF6232.3|IPF12599.2|Contig4-2295_0005|orf6.1781|orf6.7186|CA0696|RMT1|PRMT1|CaO19.3291 Major type I protein arginine methyltransferases (PRMT) involved in asymmetric dimethylation of arginine residues; involved in nuclear export of Npl3p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 206456 206953 + orf19.3292 206456 206953 1 206456 206953 206484 206927 orf19.10802|IPF6231.2|IPF12596.2|Contig4-2295_0006|Contig4-2918_0002|orf6.1782|orf6.7187|CA4602|CaO19.3292|IPF6231 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 206785 207971 - orf19.3293 206785 207971 1 207971 206785 207862 206924 orf19.10803|IPF6230.2|IPF28806.1|Contig4-2918_0003|orf6.7188|CA4603|CaO19.3293|TSC13|IPF6230 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 208265 208980 + orf19.3294 208265 208980 1 208265 208980 208292 208747 MBF1 orf19.10804|IPF23957.1|IPF6228.2|Contig4-2918_0005|orf6.7189|CA4604|CaO19.10804|CaO19.3294 Predicted ORF in Assemblies 19, 20 and 21; caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 208844 210616 - orf19.3295 208844 210616 1 210616 208844 210511 209087 orf19.10805|IPF23936.1|IPF6226.2|Contig4-2918_0006|orf6.7190|CA4605|CaO19.3295|CaO19.10805|IPF6226 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 210807 212514 + orf19.3296 210807 212514 1 210807 212514 210881 212386 orf19.10806|IPF23935.1|IPF6224.1|Contig4-2918_0008|orf6.7191|CA4606|CaO19.10806|CaO19.3296|IPF6224 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 212268 212907 - orf19.3297 212268 212907 1 212907 212268 212756 212448 orf19.10807|IPF23978.1|IPF6223.1|Contig4-2918_0009|orf6.7192|CA4607|RSM27|CaO19.10807|CaO19.3297|IPF6223 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 213520 220485 + orf19.3298 213520 220485 1 213520 220485 213644 220408 CCH1 orf19.10808|IPF23954.1|IPF6222.2|Contig4-2918_0012|orf6.7193|CA4608|CaO19.3298|CaO19.10808 Putative voltage-gated Ca2+ channel of the high affinity calcium uptake system; roles in thigmotropism, establishment of galvanotropism; transcription is regulated by Nrg1p and Mig1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 220489 222102 - orf19.3300 220489 222102 1 222102 220489 222077 220548 ZPR1 orf19.10810|IPF23933.1|IPF6215.2|Contig4-2918_0013|orf6.7195|CA4609|CaO19.3300|CaO19.10810 Protein with putative zinc finger; regulated by Gcn4p; repressed in response to amino acid starvation (3-aminotriazole treatment); upregulation correlates with clinical development of fluconazole resistance [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 224368 227069 + orf19.3301 224368 227069 1 224368 227069 224676 226883 orf19.10811|IPF23919.1|IPF19802.1|Contig4-2098_0005|orf6.7196|CA4610|CaO19.10811|MET30|CaO19.3301|IPF19802 Predicted ORF in Assemblies 19, 20 and 21; induced by heavy metal (cadmium) stress; Hog1p-induced; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 227355 230364 - orf19.3302 227355 230364 1 230364 227355 229788 227686 orf19.10812|IPF23920.1|IPF10727.1|Contig4-2491_0004|orf6.7197|CA4611|CaO19.3302|CaO19.10812|IPF10727 Predicted ORF in Assemblies 19, 20 and 21; transcription downregulated upon yeast-hyphal switch; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 230682 231503 - ntar_18 230682 231503 1 231503 230682 231453 231304 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 232533 233329 + ntar_19 232533 233329 1 232533 233329 233180 233329 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 232779 234953 - orf19.3303 232779 234953 1 234953 232779 234943 232874 orf19.10813|IPF23921.1|IPF10724.2|Contig4-2491_0009|orf6.7198|CA4612|CaO19.10813|PPM2|CaO19.3303 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 233394 233526 + ntar_20 233394 233526 1 233394 233526 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 235009 235936 - orf19.3304 235009 235936 1 235936 235009 235898 235086 orf19.10814|IPF23947.1|IPF7950.2|Contig4-2860_0018|orf6.7199|CA4613|CaO19.10814|RRP40|CaO19.3304|IPF7950 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 236066 238423 - orf19.3305 236066 238423 1 238423 236066 238310 236094 ZCF17|orf19.10815|IPF23918.1|IPF7952.2|Contig4-2860_0016|orf6.7200|CA4614|CaO19.3305|CaO19.10815|IPF7952 Putative transcription factor with zinc cluster DNA-binding motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 239100 240923 - orf19.3306 239100 240923 1 240923 239100 240923 239100 orf19.10816|IPF23928.1|IPF7955.2|Contig4-2860_0012|orf6.7201|CA4615|HOP1|CaO19.10816|CaO19.3306|IPF7955 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 239145 240704 + ntar_21 239145 240704 1 239145 240704 240095 240280 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 240982 242562 - orf19.3307 240982 242562 1 242562 240982 242513 241122 orf19.10817|IPF23937.1|IPF5761.2|Contig4-2978_0001|orf6.7202|CA4616|CaO19.3307|CaO19.10817|IPF5761 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 242658 244764 + orf19.3308 242658 244764 1 242658 244764 242750 244672 STB5|orf19.10818|IPF23925.1|IPF5760.2|Contig4-2978_0002|Contig4-2978_0004|orf6.7203|CA4617|CaO19.3308|CaO19.10818 Putative transcription factor with zinc cluster DNA-binding motif; has similarity to S. cerevisiae Stb5p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 244688 244993 - ntar_22 244688 244993 1 244993 244688 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 245182 246628 + orf19.3309 245182 246628 1 245182 246628 245215 246462 orf19.10819|IPF23939.1|IPF5757.1|Contig4-2978_0005|orf6.7204|CA4618|CaO19.10819|CaO19.3309|IPF5757 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 246608 247489 - orf19.3310 246608 247489 1 247489 246608 247422 246670 orf19.10820|IPF23950.1|IPF5756.1|Contig4-2978_0006|orf6.7205|CA4619|CaO19.3310|CaO19.10820|IPF5756 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 247688 248114 - ntar_23 247688 248114 1 248114 247688 247828 247688 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 247725 248250 + ntar_24 247725 248250 1 247725 248250 247725 248009 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 248744 249968 + orf19.3311 248744 249968 1 248744 249968 248825 249874 IFD3 orf19.10821|IPF23944.1|IPF5754.1|Contig4-2978_0008|orf6.7206|CA4620|CaO19.3311|CaO19.10821 Transcription is regulated by Mig1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 250073 252106 + orf19.3312 250073 252106 1 250073 252106 250112 251986 orf19.10822|IPF23924.1|IPF5753.1|Contig4-2978_0009|orf6.7207|CA4621|CaO19.10822|FMP29|CaO19.3312|IPF5753 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 251496 252610 - orf19.3314 251496 252610 1 252610 251496 252497 252045 orf19.10824|IPF23965.1|IPF5751.1|Contig4-2978_0010|orf6.7209|CA4622|TRS20|CaO19.10824|CaO19.3314|IPF5751 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 252942 254614 + orf19.3315 252942 254614 1 252942 254614 253167 254450 CTA9 orf19.10825|IPF23940.1|IPF5750.2|Contig4-2978_0011|orf6.7210|CA4623|CaO19.10825|CaO19.3315 Protein required for normal filamentous growth; induced during the mating process; mRNA binds to She3p; activates transcription in 1-hybrid assay in S. cerevisiae [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 254243 255031 - orf19.3317 254243 255031 1 255031 254243 254974 254627 orf19.10827|IPF18196.2|IPF5748.2|Contig4-2978_0013|orf6.7212|SRB6|CaO19.3317|CaO19.10827 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 255141 257653 - orf19.3318 255141 257653 1 257653 255141 257452 255179 orf19.10828|IPF23917.1|IPF5747.2|Contig4-2978_0015|orf6.7213|CA4624|CaO19.3318|CaO19.10828|IPF5747 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 257875 258965 + orf19.3319 257875 258965 1 257875 258965 257930 258913 orf19.10829|IPF23946.1|IPF5742.1|Contig4-2978_0016|orf6.7214|CA4625|CaO19.10829|TXL1|CaO19.3319|IPF5742 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 258474 258871 - ntar_25 258474 258871 1 258871 258474 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 259001 259354 + orf19.3320 259001 259354 1 259001 259354 259001 259354 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 259396 261346 + orf19.3321 259396 261346 1 259396 261346 259656 261182 orf19.10831|IPF5739.1|IPF28804.1|Contig4-2978_0018|orf6.5033|orf6.7216|CA4626|CaO19.3321|MRS7 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 261307 261890 - orf19.3322 261307 261890 1 261890 261307 261847 261368 DUT1 orf19.10832|IPF5736.1|IPF8317.2|Contig4-2978_0019|orf6.5032|orf6.7217|CA4627|CaO19.3322 dUTP pyrophosphatase; converts dUTP to dUMP and pyrophosphate; cell-cycle regulated if expressed in S. cerevisiae; upstream MluI and SCB transcription regulatory elements; induced by 17-beta-estradiol, ethynyl estradiol, macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 262049 263108 - orf19.3323 262049 263108 1 263108 262049 263092 262226 orf19.10833|IPF23949.1|IPF8318.2|Contig4-2976_0021|orf6.5031|CA2940|CaO19.10833|CaO19.3323|IPF8318 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 263281 264720 - orf19.3324 263281 264720 1 264720 263281 264681 263488 TIF orf19.10834|IPF23942.1|IPF8319.1|TIF1|Contig4-2976_0019|orf6.5030|CA2939|CaO19.3324|CaO19.10834 Protein similar to S. cerevisiae translation initiation factor; upregulated in highly virulent strain compared to less virulent strain; antigenic in human; flucytosine induced; translation-related genes are downregulated upon phagocytosis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 265079 267819 - orf19.3325 265079 267819 1 267819 265079 267474 265492 orf19.10835|IPF8321|IPF23923.1|IPF8321.2|Contig4-2976_0016|Contig4-2976_0018|orf6.5029|CA2938|GLG21|CaO19.3325|CaO19.10835 Protein described as glycogen synthesis initiator; regulated by Efg1p and Efh1p; Hog1p-downregulated; shows colony morphology-related gene regulation by Ssn6p; increased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 269012 270103 - orf19.3325.3 269012 270103 2 270103|269621 269999|269012 270022 269382 RPS21B IPF23913.1|IPF8325.2|Contig4-2976_0010|CA2937|RPS21B.3f|RPS21B.3 Protein described as similar to ribosomal protein S21; regulated by Nrg1p, Tup1p; shows colony morphology-related gene regulation by Ssn6p; transcription is positively regulated by Tbf1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 270279 272006 - orf19.3327 270279 272006 1 272006 270279 271985 270330 TRM2 orf19.10837|IPF23931.1|IPF8326.2|Contig4-2976_0009|orf6.5027|CA2936|CaO19.10837|TRM21|CaO19.3327|IPF8326 Predicted ORF in Assemblies 19, 20 and 21; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 272260 274556 - orf19.3328 272260 274556 1 274556 272260 274208 272385 orf19.10838|IPF23929.1|IPF11521.2|Contig4-2976_0005|orf6.5026|CA2935|CaO19.10838|HOT1|CaO19.3328|IPF11521 Predicted ORF in Assemblies 19, 20 and 21; filament induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 275355 277078 - orf19.3329 275355 277078 1 277078 275355 276963 275488 orf19.10839|IPF23934.1|IPF11515.2|Contig4-2976_0004|orf6.5025|CA2934|CaO19.3329|LCB3|CaO19.10839|IPF11515 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 278176 279437 - orf19.3330 278176 279437 1 279437 278176 279273 278233 CRL1 orf19.10840|RHO4|IPF23945.1|IPF11512.1|Contig4-2976_0002|orf6.5024|CA2933|CaO19.3330|CaO19.10840|IPF11512 Predicted GTPase of RHO family; CAAX motif geranylgeranylated; expression in S. cerevisiae causes dominant-negative inhibition of pheromone response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 280372 280907 - orf19.3330.3 280372 280907 1 280907 280372 280830 280432 POX18 CA1711|IPF11509.2|Contig4-2339_0004|CA6274|orf19.10841|POX18.3f Protein not essential for viability; similar to Candida maltosa Pox18p, which is a peroxisomal protein; Assembly 21 sequence was updated based on comparative genome analysis and new sequence data, and allelic orf19.10841 was reinstated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 281050 281340 - ntar_26 281050 281340 1 281340 281050 281340 281101 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 281622 281905 - ntar_27 281622 281905 1 281905 281622 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 282250 284392 + orf19.3331 282250 284392 1 282250 284392 282448 284148 ABC1 orf19.10842|IPF14939.2|IPF17140.3|Contig4-2339_0002|orf6.3338|orf6.5023|CA1712|CaO19.3331 Protein described as ubiquinol-cytochrome-c reductase; induced upon adherence to polystyrene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 284604 287793 + orf19.3332 284604 287793 1 284604 287793 284652 287630 orf19.10843|IPF23984.1|IPF19743.1|Contig4-2144_0003|orf6.3339|CA1713|CaO19.10843|CaO19.3332|IPF19743 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 287955 289616 + orf19.3333 287955 289616 1 287955 289616 288046 289341 orf19.10844|IPF23938.1|IPF14410.1|Contig4-2144_0005|orf6.3340|CA1714|CaO19.10844|NAB2|CaO19.3333 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 289566 290577 - orf19.3334 289566 290577 1 290577 289566 290461 289712 RPS21 orf19.10845|IPF23952.1|IPF14407.1|RPS2|Contig4-2144_0006|orf6.3341|CA1715|CaO19.3334|CaO19.10845 Predicted ribosomal protein; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage; transcription is positively regulated by Tbf1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 290832 291020 - ntar_28 290832 291020 1 291020 290832 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 291773 292640 + orf19.3335 291773 292640 1 291773 292640 291860 292462 orf19.10846|IPF23955.1|IPF17237.2|Contig4-1941_0003|orf6.3342|CA1716|CaO19.3335|CaO19.10846|IPF17237 Predicted ORF in Assemblies 19, 20 and 21; shows colony morphology-related gene regulation by Ssn6p; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 296059 296517 + orf19.3336 296059 296517 1 296059 296517 296059 296517 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 299558 300385 + orf19.3337 299558 300385 1 299558 300385 299579 300385 orf19.10847|IPF17935.2|orf6.188|CA6275|CaO19.3337|IPF7374.5f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr1 300397 301825 + orf19.3338 300397 301825 1 300397 301825 300397 301779 IPF7374.2|IPF19251.2|Contig4-2235_0002|orf6.494|orf6.4730|CA2718|CaO19.3338|IPF7374.3f|IPF7374 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 305066 306082 - orf19.3340 305066 306082 1 306082 305066 306028 305324 SOD2 orf19.10848|IPF23953.1|IPF7368.2|Contig4-2785_0004|orf6.4731|CA2719|CaO19.10848|CaO19.3340 Mitochondrial Mn-containing superoxide dismutase; protection against oxidative stress; active as homotetramer; N-terminal 34 amino acids removed upon mitochondrial import; H2O2-induced via Cap1p; alkaline downregulated, farnesol-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 306554 308594 - orf19.3341 306554 308594 1 308594 306554 308564 306633 orf19.10849|IPF23922.1|IPF7366.2|Contig4-2785_0006|orf6.4732|YDR341C|CA2720|CaO19.3341|CaO19.10849|IPF7366 Putative tRNA-Arg synthetase; essential; S. cerevisiae ortholog is essential; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr1 309035 311028 + orf19.3342 309035 311028 1 309035 311028 309137 310987 orf19.10850|IPF23927.1|IPF4799.2|Contig4-2785_0009|orf6.4733|CA2721|CaO19.10850|CaO19.3342|IPF4799 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 311162 312907 + orf19.3344 311162 312907 1 311162 312907 311215 312774 VPS17 orf19.10852|IPF23932.1|IPF4801.1|Contig4-2785_0010|orf6.4735|CA2722|CaO19.3344|CaO19.10852|IPF4801 Predicted ORF in Assemblies 19, 20 and 21; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 313068 318007 + orf19.3345 313068 318007 1 313068 318007 313177 317814 SIZ1 orf19.10853|IPF23962.1|IPF4805.2|Contig4-2944_0001|Contig4-2944_0002|orf6.4736|CA2723|CaO19.10853|CaO19.3345|IPF4805 Protein of unknown function; transcription is negatively regulated by Rim101p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 317870 318745 - orf19.3347 317870 318745 1 318745 317870 318487 317966 RPB7 orf19.10855|orf6.4738|IPF4809.1|IPF18805.2|Contig4-2944_0003|CA2724|CaO19.3347 Functional homolog of S. cerevisiae Rpb7p, an essential subunit of RNA Polymerase II; enhances hyperfilamentation of an S. cerevisiae rpb4 mutant; suppresses defects of S. cerevisiae rpb4 and ess1 mutants [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 318904 319730 + orf19.3348 318904 319730 1 318904 319730 318944 319474 orf19.10856|IPF4810.1|IPF18806.1|Contig4-2944_0004|orf6.2240|orf6.4739|CA2725|MRPL23|CaO19.3348|MRPL23A Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 319536 323471 - orf19.3349 319536 323471 1 323471 319536 323385 319681 orf19.10857|IPF23973.1|IPF4811.2|Contig4-2944_0005|Contig4-2944_0008|orf6.2239|orf6.4740|CA0987|RPB140|CaO19.3349 Putative protein of unknown function; heterozygous null mutant exhibits resistance to parnafungin in the C. albicans fitness test; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 323630 324792 + orf19.3350 323630 324792 1 323630 324792 323666 324547 MRP20 orf19.10858|IPF23948.1|IPF4814.2|Contig4-2944_0009|orf6.2238|CA0986|CaO19.3350|CaO19.10858|IPF4814 Protein described as component of mitochondrial ribosome; decreased expression in hyphae compared to yeast-form cells [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 324874 326042 - orf19.3351 324874 326042 2 326042|325756 325935|324874 325957 324904 orf19.10859|IPF18790.2|IPF4815.2|Contig4-2944_0010|orf6.2237|CA0985|CaO19.10859|CaO19.3351|IPF4815.3f|IPF4815 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 325236 325474 + ntar_29 325236 325474 1 325236 325474 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 326217 327581 - orf19.3352 326217 327581 1 327581 326217 327443 326445 orf19.10860|IPF4817.1|IPF17315.2|IPF18807.1|Contig4-2944_0011|orf6.2236|orf6.2296|CA6276|IPF4817.5f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 327654 328131 + ntar_30 327654 328131 1 327654 328131 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 331210 332473 + orf19.3353 331210 332473 1 331210 332473 331372 332055 orf19.10861|IPF4820.2|IPF18808.1|IPF18809.1|Contig4-2944_0016|orf6.2235|orf6.2295|CA1022|IPF4820.5f|IPF4820 Protein described as similar to a mitochondrial complex I intermediate-associated protein; fluconazole-downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 331416 332205 - ntar_31 331416 332205 1 332205 331416 332193 332050 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 332693 334297 + orf19.3354 332693 334297 2 332693|333322 332752|334297 332739 334096 orf19.10862|IPF28807.1|Contig4-2331_0004|orf6.2294|CaO19.10862|RPS42|CaO19.3354 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 334442 336074 + orf19.3355 334442 336074 1 334442 336074 334662 336044 ISN1 orf19.10863|IPF4824.1|IPF28805.1|Contig4-2331_0002|orf6.1924|orf6.2293|CA1020|CaO19.3355|IPF4824 Putative inosine 5'-monophosphate 5'-nucleotidase; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 336138 336219 - ts(uga)1 336138 336219 1 336219 336138 tS(UGA)1.2 tRNA-Ser predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 336662 341515 - orf19.3356 336662 341515 1 341515 336662 341515 336719 ESP1 orf19.10864|IPF23960.1|IPF14196.2|Contig4-2331_0010|Contig4-2755_0001|Contig4-2755_0003|orf6.1925|CA0789|CaO19.3356|CaO19.10864 Predicted ORF in Assemblies 19, 20 and 21; mutation confers increased sensitivity to nocodazole; periodic mRNA expression, peak at cell-cycle S/G2 phase; mRNA binds to She3p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr1 341723 342534 - orf19.3357 341723 342534 1 342534 341723 342459 341947 orf19.10865|IPF23956.1|IPF14193.2|Contig4-2755_0005|orf6.1926|CA0790|CaO19.10865|CaO19.3357|IPF14193 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 342805 344018 - orf19.3358 342805 344018 1 344018 342805 343920 342949 LSC1 orf19.10866|orf6.1927|IPF23941.1|IPF14191.1|Contig4-2755_0006|CA0791|CaO19.10866|CaO19.3358 Protein described as succinate-CoA ligase subunit; transcriptionally regulated by iron; expression greater in high iron; fluconazole-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 344908 345293 + ntar_32 344908 345293 1 344908 345293 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 345579 348960 + orf19.3359 345579 348960 1 345579 348960 345579 348779 ARP8 orf19.10867|IPF14479.2|IPF18872.2|Contig4-2755_0011|orf6.1928|orf6.2524|orf6.791|CA1164|CaO19.3359 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to toxic ergosterol analog, and to amphotericin B [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 348191 348894 - ntar_33 348191 348894 1 348894 348191 348490 348191 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 350957 353524 + orf19.3360 350957 353524 1 350957 353524 351115 353118 orf19.10868|IPF19902.1|IPF19845.1|Contig4-2197_0001|Contig4-2891_0002|orf6.2525|orf6.792|CA1165|CaO19.3360|IPF19902 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 353430 354131 - ntar_34 353430 354131 1 354131 353430 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 354223 354295 + ta(agc)3 354223 354295 1 354223 354295 tA(AGC)3.2 tRNA-Ala predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 357089 359483 + orf19.4551 357089 359483 1 357089 359483 357096 359483 CTN1 orf19.12026|orf19.10869|CAT1|IPF18747.1|IPF19359.2|IPF9082.2|YAT1|Contig4-2891_0007|orf6.285|orf6.2526|orf6.6697|CA4207|orf19.3361|orf19.361|CaO19.12026|CaO19.4551 Predicted carnitine acetyl transferase; required for growth on nonfermentable carbon sources but not for hyphal growth or virulence in mouse systemic model; transcription induced in macrophage; macrophage/pseudohyphal-repressed after 16 hr [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chr1 360889 363080 + orf19.4550 360889 363080 1 360889 363080 361046 362947 orf19.12025|IPF22708.1|IPF9079.2|Contig4-2891_0009|Contig4-2891_0010|orf6.6696|CA4206|CaO19.12025|CaO19.4550|IPF9079 Predicted membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 363929 366456 + orf19.4549 363929 366456 1 363929 366456 364189 366324 FGR38 orf19.12024|IPF9076.2|IPF14747.3|Contig4-2122_0008|Contig4-2845_0004|Contig4-2891_0011|orf6.6695|orf6.95|CA4205|LPF31|CaO19.4549|IFA10 Protein lacking an ortholog in S. cerevisiae; member of a family of related proteins; transposon mutation affects filamentous growth; macrophage-induced gene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 366637 367949 + orf19.4548 366637 367949 1 366637 367949 366747 367877 MAK32 orf19.12023|IPF22716.1|IPF14749.2|Contig4-2122_0005|orf6.6694|orf6.96|CA0013|CaO19.4548 Downregulated upon adherence to polystyrene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 367772 370132 - orf19.4546 367772 370132 1 370132 367772 369824 367950 HOL4 orf19.12021|IPF14750.2|IPF28353.1|Contig4-2122_0003|orf6.6692|orf6.97|CA4204|CaO19.4546 Protein described as an ion transporter; alkaline upregulated by Rim101p; Plc1p-regulated; caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 372140 375602 + orf19.4545 372140 375602 2 372140|372440 372283|375602 372242 375457 SWI4 orf19.12020|IPF17386.2|IPF28367.1|orf6.6691|CA4203|CaO19.4545|SWI4.3f Predicted ORF in Assemblies 19, 20 and 21; periodic mRNA expression, peak at cell-cycle G1/S phase; predicted, conserved MBF binding sites upstream of G1/S-regulated genes [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 375786 376717 + orf19.4544 375786 376717 1 375786 376717 375852 376571 orf19.12019|IPF22722.1|IPF8047.2|orf6.6690|CA4202|CaO19.12019|CaO19.4544|IPF8047 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 376575 378226 - orf19.4543 376575 378226 1 378226 376575 378191 376662 UGA2 orf19.12018|IPF22712.1|IPF8048.2|orf6.6689|CA4201|UGA22|CaO19.12018|CaO19.4543|IPF8048 Protein not essential for viability; similar to S. cerevisiae Uga2p, which is succinate semialdehyde dehydrogenase with a role in glutamate catabolism; transcription regulated by Mig1p, Tup1p, Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 378422 379726 - orf19.4542 378422 379726 1 379726 378422 379667 378480 orf19.12017|IPF22715.1|IPF8051.2|Contig4-2727_0009|Contig4-2727_0010|orf6.6688|CA4200|CaO19.12017|CCL1|CaO19.4542 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 379900 381161 - orf19.4540 379900 381161 1 381161 379900 380801 380229 UBC8 orf19.12015|IPF22726.1|IPF8054.2|Contig4-2727_0007|orf6.6686|CA4199|CaO19.12015|CaO19.4540 Protein similar to S. cerevisiae Ubc8p; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 381370 382417 - orf19.4539 381370 382417 1 382417 381370 382108 381554 orf19.12014|IPF22724.1|IPF8055.2|Contig4-2727_0005|orf6.6685|CA4198|CaO19.4539|CaO19.12014|IPF8055 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 382638 383606 - orf19.4538 382638 383606 1 383606 382638 383606 382776 orf19.12013|IPF22721.1|IPF8057.2|Contig4-2727_0003|orf6.6684|CA4197|CaO19.12013|RNA15|CaO19.4538|IPF8057 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 383739 384842 + orf19.4537 383739 384842 1 383739 384842 383769 384686 orf19.12012|IPF22720.1|IPF8059.2|Contig4-2727_0002|orf6.6683|CA4196|DST1|CaO19.4537|CaO19.12012 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 384602 386409 - orf19.4536 384602 386409 1 386409 384602 386296 384806 CYS4 orf19.12011|IPF22713.1|IPF8061.2|Contig4-2727_0001|orf6.6682|CA4195|CaO19.4536|CaO19.12011 Predicted enzyme of sulfur amino acid biosynthesis; antigenic in mouse; upregulated in biofilm; alkaline upregulated; macrophage/pseudohyphal-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 386496 388991 - orf19.4535 386496 388991 1 388991 386496 388940 386613 PTR3 orf19.12010|IPF22706.1|IPF19799.1|Contig4-1672_0002|Contig4-2727_0013|orf6.6681|CA4194|CaO19.12010|CaO19.4535 Protein not essential for viability; similar to S. cerevisiae Ptr3p, which is a sensor of external amino acids; increased expression observed in an ssr1 homozygous null mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 389152 390970 - orf19.4534 389152 390970 1 390970 389152 390816 389287 orf19.12009|IPF22711.1|IPF7535.2|Contig4-1672_0004|orf6.6680|CA4193|CaO19.4534|CaO19.12009|IPF7535 Predicted ORF in Assemblies 19, 20 and 21; macrophage-downregulated gene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 391076 392894 - orf19.4533 391076 392894 1 392894 391076 392780 391263 orf19.12008|IPF22714.1|IPF7533.2|Contig4-2751_0002|orf6.6679|CA4192|CaO19.12008|CaO19.4533|IPF7533 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 393089 394481 + orf19.4532 393089 394481 1 393089 394481 393312 394376 orf19.12007|IPF7531.2|IPF28355.1|Contig4-2751_0004|orf6.6678|CA4191|CaO19.4532|IPF7531 Predicted ORF in Assemblies 19, 20 and 21; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 395499 399427 + orf19.4531 395499 399427 1 395499 399427 395603 399427 orf19.12006|IPF7530.2|IPF28363.1|Contig4-2751_0006|Contig4-2751_0007|orf6.6677|CA4190|CaO19.4531|IPF7530 Putative PDR-subfamily ABC transporter [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr1 400555 402162 + orf19.4530.1 400555 402162 2 400555|400924 400637|402162 400609 401995 IPF22717.1|IPF7527.2|Contig4-2751_0008|CA4189|IPF7527 ORF Predicted by Annotation Working Group; regulated by Nrg1p, Tup1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 402105 402829 - orf19.4529 402105 402829 1 402829 402105 402787 402281 orf19.12004|IPF7525|IPF22725.1|IPF7525.1|Contig4-2751_0010|orf6.6675|CA4188|CaO19.12004|CaO19.4529 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 402967 403729 - orf19.4528 402967 403729 1 403729 402967 403707 403162 orf19.12003|IPF7524.1|IPF18665.2|Contig4-2751_0011|orf6.6674|CA4187|CaO19.12003|CaO19.4528|IPF7524 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 404176 405404 + ntar_35 404176 405404 1 404176 405404 404910 405035 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 405294 405736 + ntar_36 405294 405736 1 405294 405736 405294 405512 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 406323 407278 - ntar_37 406323 407278 1 407278 406323 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 406691 408328 + orf19.4527 406691 408328 1 406691 408328 406691 408328 HGT1 orf19.12002|HGT11|IPF7518.2|IPF9983.2|Contig4-2702_0004|orf6.3044|orf6.6673|CA1506|CaO19.4527 High-affinity glucose transporter, member of major facilitator superfamily; transcription induced by progesterone and by drugs including chloramphenicol and benomyl; likely essential for growth, based on an insertional mutagenesis strategy [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 407702 408212 - ntar_38 407702 408212 1 408212 407702 408112 407822 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 408596 409058 + ntar_39 408596 409058 1 408596 409058 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 411358 412386 + orf19.4526 411358 412386 1 411358 412386 411358 412386 HSP30 orf19.12001|IPF22718.1|IPF9978.2|Contig4-2702_0008|Contig4-2702_0009|orf6.3045|CA1507|CaO19.12001|CaO19.4526 Protein described as similar to heat shock protein; fluconazole-downregulated; amphotericin B induced [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 412836 414053 + orf19.4525 412836 414053 1 412836 414053 412836 413840 orf19.12000|IPF22719.1|IPF9977.2|Contig4-2702_0011|orf6.3046|CA1508|CaO19.12000|CaO19.4525|IPF9977 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 413963 416372 - orf19.4524 413963 416372 2 416372|416158 416237|413963 416295 414112 ZCF24|orf19.11999|IPF22709.1|IPF19920.1|Contig4-2702_0012|orf6.3047|CA1509|IPF19920|IPF19920.3 Predicted zinc-finger protein of unknown function; caspofungin induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 416354 417696 + orf19.4523 416354 417696 1 416354 417696 416475 417098 orf19.11998|IPF22723.1|IPF9973.2|Contig4-2702_0013|orf6.3048|CA1510|CaO19.11998|CaO19.4523|IPF9973 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 417015 417767 - orf19.4522 417015 417767 1 417767 417015 417694 417101 orf19.11997|IPF22727.1|IPF9972.2|orf6.3049|CA1511|CaO19.4522|CaO19.11997|IPF9972.3eoc Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr1 417954 420645 - orf19.3661 417954 420645 1 420645 417954 420516 418042 orf19.11145|IPF23582.1|IPF11332.3|Contig4-2575_0009|orf6.135|orf6.2135|CA0927|UBP16|CaO19.3661|IPF11332|IPF11332.2 Predicted ORF in Assemblies 19, 20 and 21; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 421076 424102 - orf19.3663 421076 424102 1 424102 421076 423870 421288 PHO91 orf19.11147|IPF23580.1|IPF11335.1|Contig4-2575_0007|orf6.2133|CA0926|CaO19.11147|CaO19.3663|IPF11335 Putative low-affinity phosphate transporter; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 425712 427097 + orf19.3663.1 425712 427097 2 425712|426401 426036|427097 426009 426639 Predicted ORF in Assembly 20 and 21; gene has intron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 427823 428892 + orf19.3664 427823 428892 1 427823 428892 427866 428861 HSP31 orf19.11148|IPF12039.2|IPF11340.3|Contig4-1615_0002|Contig4-1615_0004|orf6.6475|CA4034|CaO19.3664 Protein repressed during the mating process [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 429338 430814 + orf19.3665 429338 430814 1 429338 430814 429394 430533 orf19.11149|IPF23602.1|IPF12040.2|Contig4-3059_0003|orf6.6476|CA4035|SET6|CaO19.3665|CaO19.11149|IPF12040 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 430048 432058 - orf19.3666 430048 432058 1 432058 430048 432017 430530 orf19.11150|IPF23597.1|IPF12042.2|Contig4-3059_0004|orf6.6477|CA4036|CaO19.3666|CaO19.11150|IPF12042 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 432227 434005 + orf19.3667 432227 434005 1 432227 434005 432248 433864 orf19.11151|IPF23592.1|IPF12044.2|Contig4-3059_0005|orf6.6478|CA4037|CaO19.3667|KIP99|CaO19.11151|KIP31 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 434337 436145 - orf19.3668 434337 436145 1 436145 434337 436072 434435 HGT2 orf19.11152|RGT2|IPF23590.1|IPF5315.2|Contig4-3059_0006|orf6.6479|CA4038|CaO19.3668|CaO19.11152|HGT12 Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; expressed in rich medium with 2% glucose [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 434651 435061 + ntar_40 434651 435061 1 434651 435061 434651 434983 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 435499 435957 + ntar_41 435499 435957 1 435499 435957 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 442376 444335 - orf19.3669 442376 444335 1 444335 442376 444259 442472 SHA3 orf19.11153|SKS1|IPF23589.1|IPF5304.2|Contig4-3059_0011|orf6.6480|CA4039|CaO19.11153|CaO19.3669 Protein similar to S. cerevisiae Sha3p, which is a serine/threonine kinase involved in glucose transport; transposon mutation affects filamentous growth; fluconazole-induced; ketoconazole-repressed; induced in response to alpha pheromone [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 446677 447274 + ntar_42 446677 447274 1 446677 447274 446677 446904 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 447406 447641 + ntar_43 447406 447641 1 447406 447641 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 448869 451094 - orf19.3670 448869 451094 1 451094 448869 450824 449277 GAL1 orf19.11154|IPF23594.1|IPF5296.2|Contig4-3059_0016|orf6.6481|CA4040|CaO19.11154|CaO19.3670 Galactokinase; transcription regulated by galactose; transcription regulated by Mig1p and Tup1p; not required for systemic mouse virulence; farnesol-downregulated in biofilm; fluconazole-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 451304 451648 - orf19.3671 451304 451648 1 451648 451304 451648 451304 orf19.11155|IPF23619.1|IPF28685.1|orf6.6482|CaO19.3671|CaO19.11155 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 451984 454259 + orf19.3672 451984 454259 1 451984 454259 452186 454213 GAL10 orf19.11156|IPF23585.1|IPF5294.2|Contig4-3059_0020|orf6.6483|CA4041|CaO19.3672|CaO19.11156 UDP-glucose 4-epimerase, required for galactose utilization; mutant shows cell wall defects and increased filamentation; fluconazole-induced; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 454395 455266 + orf19.3673 454395 455266 1 454395 455266 454418 454924 orf19.11157|IPF23609.1|IPF5292.1|Contig4-3059_0021|orf6.6484|CA4042|TRS23|CaO19.11157|CaO19.3673 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 454883 455875 - orf19.3674 454883 455875 1 455875 454883 455845 454883 GAL102 orf19.11158|IPF23603.1|IPF5291.1|Contig4-3059_0023|orf6.6485|CA4043|TGD99|CaO19.3674|CaO19.11158|IPF5291 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to toxic ergosterol analog [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr1 456465 458032 + orf19.3675 456465 458032 1 456465 458032 456773 457933 GAL7 orf19.11159|IPF23601.1|IPF9203.2|Contig4-2775_0014|orf6.6486|CA4044|CaO19.11159|CaO19.3675 Predicted ORF in Assemblies 19, 20 and 21; macrophage/pseudohyphal-repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 458358 459438 + orf19.3676 458358 459438 1 458358 459438 458388 459326 ABP140 orf19.11160|IPF23604.1|IPF9204.1|Contig4-2775_0013|orf6.6487|CA4045|CaO19.3676|CaO19.11160 Protein similar to S. cerevisiae actin-binding protein Abp140p; induced upon biofilm formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 459212 460327 - orf19.3677 459212 460327 1 460327 459212 460152 459316 orf19.11161|IPF23607.1|IPF9205.2|Contig4-2775_0011|orf6.6488|CA4046|CaO19.11161|ATG5|CaO19.3677|IPF9205 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 460783 463066 + orf19.3678 460783 463066 1 460783 463066 461092 462807 orf19.11162|IPF9206|IPF23591.1|IPF9206.2|Contig4-2775_0010|orf6.6489|CA4047|CaO19.11162|CaO19.3678 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 462506 463924 - orf19.3679 462506 463924 1 463924 462506 463884 462874 orf19.11163|IPF9207.2|IPF28682.1|Contig4-2775_0009|orf6.6490|CA4048|CaO19.3679|CaO19.11163|IPF9207 Predicted ORF in Assemblies 19, 20 and 21; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 465099 468016 + orf19.3680 465099 468016 1 465099 468016 465662 467674 7-Sep orf19.11164|IPF23586.1|IPF9210.2|Contig4-2775_0002|orf6.875|CA6210|SHS1|CaO19.11164|CaO19.3680 Septin, required for wild-type invasive growth in vitro but not required for virulence in a mouse model of systemic infection; localizes to hyphal septum or bud neck; Asn-rich; aberrant gel mobility [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 468557 468790 + ntar_44 468557 468790 1 468557 468790 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 469048 472041 + orf19.3681 469048 472041 1 469048 472041 469144 471771 orf19.11165|IPF10376.1|IPF28677.1|Contig4-2750_0016|orf6.2498|CA1147|CaO19.11165|KAP95|CaO19.3681 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 472250 472619 - ntar_45 472250 472619 1 472619 472250 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 472740 474071 + ntar_46 472740 474071 1 472740 474071 473172 473447 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 472850 473260 - ntar_47 472850 473260 1 473260 472850 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 473363 474023 - ntar_48 473363 474023 1 474023 473363 473989 473867 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 474174 475920 + orf19.3682 474174 475920 1 474174 475920 474954 475679 CWH8 orf19.11166|IPF23608.1|IPF10381.2|Contig4-2750_0005|orf6.2497|CA1146|CaO19.11166|CAX4|CaO19.3682 Putative dolichyl pyrophosphate (Dol-P-P) phosphatase; ketoconazole-induced; expression is increased in a fluconazole-resistant isolate; clade-associated gene expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 475769 477186 - orf19.3683 475769 477186 1 477186 475769 477070 475931 orf19.11167|IPF10382.2|IPF18541.2|Contig4-2750_0004|orf6.2496|orf6.3883|CA1145|GCS1|CaO19.3683 Putative transcription factor with zinc finger DNA-binding motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 477313 478163 + ntar_49 477313 478163 1 477313 478163 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 477321 478239 - orf19.3684 477321 478239 1 478239 477321 478218 477340 orf19.11168|IPF19650.1|IPF18542.1|IPF19649.1|Contig4-2750_0002|orf6.2495|orf6.3882|CA1144|SPS19|SPS19.5f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 478505 481653 - orf19.3685 478505 481653 1 481653 478505 481603 478661 PSY2 orf19.11169|IPF18751.2|IPF13744.2|orf6.2494|orf6.3881|CA2114|CaO19.3685|IPF13744 Predicted ORF in Assemblies 19, 20 and 21; macrophage-induced gene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 482242 483625 - orf19.3686 482242 483625 1 483625 482242 483625 482414 orf19.11170|IPF23600.1|IPF13746.2|Contig4-2096_0001|orf6.3880|CA2113|CaO19.11170|ATP12|CaO19.3686 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 483580 484241 + orf19.3687 483580 484241 1 483580 484241 483733 484098 orf19.11171|IPF23613.1|IPF13747.2|Contig4-2096_0002|orf6.3879|CA2112|CaO19.11171|PFD1|CaO19.3687 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 483923 484638 - orf19.3688 483923 484638 1 484638 483923 484574 484209 orf19.11172|IPF23616.1|IPF13748.2|Contig4-2096_0003|orf6.3878|CA2111|CaO19.3688|IPF13748 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 484733 486642 - orf19.3689 484733 486642 1 486642 484733 486512 484881 orf19.11173|orf19.11174|IPF23610.1|IPF23605.1|IPF18544.1|IPF13749.2|Contig4-2096_0004|Contig4-2096_0006|Contig4-2582_0008|orf6.3877|orf6.3876|CA2110|CA2109|orf19.3690|IPF13749.3f Predicted ORF in Assemblies 19, 20 and 21; decreased expression observed in an ssr1 homozygous null mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 487070 488344 - orf19.3690.2 487070 488344 2 488344|487747 488214|487070 488232 487383 IPF23615.1|IPF10719.1|CA2108|RPL26A.3f|RPL26A.3 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 488546 489165 - tr(ccg)1 488546 489165 2 489165|488717 488749|488546 489158 488936 tR(CCG)1.2 tRNA-Arg predicted by tRNAscan-SE [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr1 489308 490466 + orf19.3691 489308 490466 1 489308 490466 489369 490175 orf19.11175|IPF23606.1|IPF10716.1|Contig4-2582_0002|orf6.3875|CA2107|FMP17|CaO19.11175|CaO19.3691|IPF10716 Predicted ORF in Assemblies 19, 20 and 21; ketoconazole-repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 490289 492214 - orf19.3693 490289 492214 1 492214 490289 492214 490289 PGA5 orf19.11177|IPF23587.1|IPF10714.2|Contig4-2582_0001|orf6.3873|GAS12|CA2106|CaO19.11177|CaO19.3693|IPF10714 [NOT TRANSCRIBED?] Putative GPI-anchored protein; fungal-specific (no human or murine homolog) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 492498 496408 - orf19.3694 492498 496408 1 496408 492498 496257 492625 orf19.11178|IPF23618.1|IPF10711.2|Contig4-1599_0004|Contig4-2582_0009|orf6.3872|CA2105|CaO19.3694|CaO19.11178|IPF10711 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 497860 499098 - orf19.2925 497860 499098 1 499098 497860 499071 498391 orf19.10442|IPF24343.1|IPF15237.1|Contig4-2057_0002|orf6.1561|CA0561|CIN4|CaO19.10442|CaO19.2925 Predicted ORF in Assemblies 19, 20 and 21 (see Locus History Note for Assembly 19 correction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr1 499153 501955 + orf19.2926 499153 501955 1 499153 501955 499258 501750 orf19.10443|IPF24250.1|IPF15236.2|Contig4-2057_0003|Contig4-2057_0005|Contig4-2249_0007|orf6.1562|CA0562|CaO19.10443|CaO19.2926|PSO2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 501945 503666 - orf19.2927 501945 503666 1 503666 501945 503425 502091 MNN11 orf19.10444|IPF18555.2|IPF14216.2|Contig4-2249_0006|orf6.1563|CA0563|CaO19.2927 Protein with similarity to mannosyltransferases [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 504038 505444 - orf19.2928 504038 505444 1 505444 504038 505263 504190 orf19.10445|IPF14219.2|IPF18940.2|Contig4-2249_0005|orf6.1564|orf6.3784|CA0564|CaO19.2928|IPF14219|CA2042 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 505502 505759 + ntar_50 505502 505759 1 505502 505759 505502 505660 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 505711 513014 - orf19.2929 505711 513014 2 513014|511700 512883|505711 511700 506007 GSC1 orf19.10446|FKS1|IPF24355.1|IPF10681.2|GSL21|Contig4-2249_0002|orf6.3785|GSL2|CA2043|CaO19.2929|CaO19.10446 Subunit of beta-1,3-glucan synthase; essential; gsc1 allele determines resistance/sensitivity to echinocandin antifungals; 16 predicted membrane-spanning regions; mRNA abundance declines after yeast-to-hyphal transition; fungal-specific [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr1 514736 514981 + ntar_51 514736 514981 1 514736 514981 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 515107 515451 + ntar_52 515107 515451 1 515107 515451 515107 515274 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 515619 517792 - orf19.2930 515619 517792 1 517792 515619 517581 515635 orf19.10447|IPF10668.2|IPF18514.2|Contig4-2150_0003|orf6.3786|orf6.3995|CA2044|CaO19.2930|IPF10668 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 518120 519369 - orf19.2933 518120 519369 1 519369 518120 519223 518222 orf19.10450|IPF10665.2|IPF8107.2|Contig4-2841_0001|Contig4-2841_0002|orf6.3789|orf6.3997|CA2045|CaO19.2933|IPF8107 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 519478 520051 + ntar_53 519478 520051 1 519478 520051 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 519885 520682 - orf19.2934 519885 520682 1 520682 519885 520640 520110 orf19.10451|IPF8108.2|IPF28911.1|Contig4-2841_0004|orf6.3790|orf6.3998|CA2046|BUD20|CaO19.2934|IPF8108 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 520935 522238 + orf19.2935 520935 522238 2 520935|521337 520989|522238 521342 522004 RPL10 orf19.10452|IPF8109.2|IPF28907.1|Contig4-2841_0005|orf6.3791|orf6.3999|CA2047|CaO19.2935 Putative ribosomal protein; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases downregulated upon phagocytosis by murine macrophage; transcription regulated upon yeast-hyphal switch; intron in 5'-UTR [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr1 522422 523459 + orf19.2936 522422 523459 1 522422 523459 522669 523139 orf19.10453|IPF18554.2|IPF8110.2|Contig4-2841_0007|orf6.4000|CA2197|CaO19.10453|CaO19.2936|IPF8110 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 523880 524995 + orf19.2937 523880 524995 1 523880 524995 524030 524788 PMM1 orf19.10454|IPF24340.1|IPF8112.1|Contig4-2841_0009|orf6.4001|CA2198|CaO19.10454|CaO19.2937 Phosphomannomutase; enzyme of O- and N-linked mannosylation; interconverts mannose-6-phosphate and mannose-l-phosphate; functional homolog of S. cerevisiae Sec53p; antigenic during murine systemic infection [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 524805 526953 - orf19.2938 524805 526953 1 526953 524805 526916 524895 orf19.10455|IPF8113|IPF24263.1|IPF8113.2|Contig4-2841_0010|orf6.4002|CA2199|CaO19.2938|FMP25|CaO19.10455 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 527105 527898 + orf19.2939 527105 527898 1 527105 527898 527154 527780 orf19.10456|IPF24347.1|IPF8114.2|Contig4-2841_0011|orf6.4003|CA2200|CaO19.10456|FMP32|CaO19.2939|IPF8114 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 528014 528866 + orf19.2940 528014 528866 1 528014 528866 528083 528814 orf19.10457|IPF24341.1|IPF19943.1|Contig4-2841_0013|orf6.4004|CA2201|BOS1|CaO19.10457|CaO19.2940 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 530041 532028 + orf19.2941 530041 532028 1 530041 532028 530226 531962 SCW4 orf19.10458|IPF24282.1|IPF8122.1|Contig4-2841_0015|orf6.4005|CA2202|CMP66|CaO19.10458|CaO19.2941 Putative cell wall protein; exogenously expressed protein is a substrate for Kex2p processing in vitro; expression is regulated upon white-opaque switching; alkaline downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 532146 532324 + ntar_54 532146 532324 1 532146 532324 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 532269 534323 - orf19.2942 532269 534323 1 534323 532269 534217 532457 DIP5 orf19.10459|orf19.10460|IPF24319.1|IPF24337.1|IPF8123.2|IPF10236.2|DIP51|Contig4-2841_0016|orf6.4006|orf6.4007|CA2203|CA2204|orf19.2943|DIP52|DIP51.3f Putative permease for dicarboxylic amino acids; mutation confers hypersensitivity to toxic ergosterol analog; transcriptionally induced upon phagocytosis by macrophage; Gcn4p-regulated; upregulated by Rim101p at pH 8 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 536181 536491 - ntar_55 536181 536491 1 536491 536181 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 536589 536661 - tr(ucu)4 536589 536661 1 536661 536589 tR(UCU)4.2 tRNA-Arg predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 536985 537284 + orf19.2943.5 536985 537284 1 536985 537284 536985 537284 IPF10241.3 [NOT TRANSCRIBED?] ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 537126 539136 - orf19.2945 537126 539136 1 539136 537126 539136 537442 PUT4 orf19.10462|IPF24286.1|IPF10243.2|Contig4-2682_0007|orf6.6671|CA4186|CaO19.10462|CaO19.2945 Putative proline permease; fungal-specific (no human or murine homolog); repressed during the mating process [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 537849 538389 + ntar_56 537849 538389 1 537849 538389 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 538653 539002 + ntar_57 538653 539002 1 538653 539002 538683 538817 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 539047 539470 + ntar_58 539047 539470 1 539047 539470 539047 539229 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 540058 541569 + orf19.2946 540058 541569 1 540058 541569 540058 541569 HNM4 orf19.10463|IPF24296.1|IPF10246.2|Contig4-2682_0005|orf6.6670|CA4185|CaO19.10463|CaO19.2946 Putative choline permease; fungal-specific (no human or murine homolog) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 541584 542739 - orf19.2947 541584 542739 1 542739 541584 542657 541779 SNZ1 orf19.10464|IPF24330.1|IPF10248.2|Contig4-2682_0003|orf6.6669|CA4184|SNZ99|CaO19.2947|CaO19.10464 Detected in stationary phase cultures; soluble in hyphae; induced on yeast to hyphal switch, in response to 3-aminotriazole, or in azole-resistant strain overexpressing MDR1; regulated by Gcn4p, macrophage; no human/murine homolog [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 543965 544968 + orf19.2948 543965 544968 1 543965 544968 544113 544862 SNO1 orf19.10465|IPF4408.2|IPF28909.1|Contig4-2696_0001|orf6.6668|CA4183|CaO19.2948 Protein of unknown function expressed during stationary phase; transcription is regulated by Tup1p, Efg1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 545055 549479 + orf19.2949 545055 549479 1 545055 549479 545064 549452 orf19.10466|IPF19797.1|IPF28917.1|Contig4-2696_0005|orf6.6667|CA4182|CaO19.10466|IML1|CaO19.2949|IPF19797 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr1 549413 550678 - orf19.2951 549413 550678 1 550678 549413 550630 549551 HOM6 orf19.10468|IPF24318.1|IPF4417.2|Contig4-2696_0009|orf6.6665|CA4181|CaO19.2951|CaO19.10468 Protein described as homoserine dehydrogenase; regulated by Gcn4p; induced in response to amino acid starvation (3-aminotriazole treatment); macrophage-induced protein; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 550897 552485 - orf19.2952 550897 552485 1 552485 550897 552433 550994 EXG2 orf19.10469|orf6.6664|IPF24292.1|IPF4419.1|Contig4-2696_0012|Contig4-2696_0013|Contig4-2696_0015|CA4180|CaO19.2952|CaO19.10469 GPI-anchored cell wall protein, similar to S. cerevisiae Exg2p, which is an exo-1,3-beta-glucosidase; predicted Kex2p substrate; induced during cell wall regeneration [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 552567 553516 - orf19.2953 552567 553516 1 553516 552567 553430 552915 orf19.10470|IPF24356.1|IPF4420.1|Contig4-2696_0016|orf6.6663|CA4179|TOM20|CaO19.2953|CaO19.10470 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 553770 554598 + orf19.2954 553770 554598 1 553770 554598 553815 554417 orf19.10471|IPF24348.1|IPF4421.2|Contig4-2696_0017|orf6.6662|CA4178|CaO19.2954|CaO19.10471|IPF4421 Predicted ORF in Assemblies 19, 20 and 21; repressed by nitric oxide; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 554499 555520 - orf19.2956 554499 555520 1 555520 554499 555461 554634 MGM101 orf19.10473|IPF24328.1|IPF4423.1|Contig4-2696_0018|orf6.6660|CA4177|CaO19.2956|CaO19.10473 Putative mitochondrial genome maintenance protein; fungal-specific (no human or murine homolog); mutation confers hypersensitivity to tubercidin (7-deazaadenosine) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 555732 558158 - orf19.2957 555732 558158 1 558158 555732 558158 555732 orf19.10474|IPF24251.1|IPF4425.2|orf6.6659|MNN4|CA4176|CaO19.2957|MNN43|CaO19.10474|IFX2|IPF4425.repeat1 Predicted ORF in Assemblies 19, 20 and 21; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 558798 561737 - orf19.2958 558798 561737 1 561737 558798 561509 558981 orf19.10475|IPF24247.1|IPF4427.2|Contig4-2873_0015|orf6.6658|CA4175|CaO19.10475|MNN44|CaO19.2958|IFX1|IPF4425.repeat2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 562417 562719 - orf19.2959 562417 562719 1 562719 562417 562719 562417 orf19.10476|orf6.6657|CaO19.2959|CaO19.10476 Predicted ORF from Assembly 19; removed from Assembly 20; subsequently reinstated in Assembly 21 based on comparative genome analysis [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 563797 564120 + ntar_59 563797 564120 1 563797 564120 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 564086 564830 - orf19.2959.1 564086 564830 1 564830 564086 564488 564315 IPF24404.1|IPF4430.1|CA4174|IPF4430|IPF4119.5 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 565057 565230 - ntar_60 565057 565230 1 565230 565057 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 565673 567305 + orf19.2960 565673 567305 1 565673 567305 565743 567233 FRS2 orf19.10477|IPF24297.1|IPF4431.1|Contig4-2873_0010|orf6.6656|CA4173|CaO19.10477|CaO19.2960 Putative tRNA-Phe synthetase; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 567452 569143 + orf19.2961 567452 569143 1 567452 569143 567502 568695 orf19.10478|IPF24305.1|IPF4432.2|Contig4-2873_0007|orf6.6655|CA4172|CaO19.2961|CaO19.10478|IPF4432 Putative transcription factor with zinc finger DNA-binding motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 574140 575536 + orf19.2962 574140 575536 1 574140 575536 574280 575167 orf19.10479|IPF24329.1|IPF7785.1|Contig4-2716_0004|orf6.6654|CA4171|CaO19.10479|CaO19.2962|IPF7785 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 574623 576483 - orf19.2963 574623 576483 1 576483 574623 576458 575538 orf19.10480|IPF24327.1|IPF7784.2|Contig4-2716_0005|orf6.6653|CA4170|CaO19.10480|CaO19.2963|IPF7784 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 576630 579126 - orf19.2964 576630 579126 1 579126 576630 579105 576718 orf19.10481|IPF24254.1|IPF7783.2|Contig4-2716_0006|Contig4-2716_0007|orf6.6652|CA4169|CaO19.2964|RSC2|CaO19.10481 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 579765 581023 + orf19.2965 579765 581023 1 579765 581023 579810 580862 orf19.10482|IPF24314.1|IPF7781.2|Contig4-2716_0008|orf6.6651|CA4168|CaO19.10482|CaO19.2965|IPF7781 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 581084 581678 + orf19.2965.1 581084 581678 2 581084|581519 581413|581678 581272 581568 Predicted ORF in Assembly 20 and 21; similar to human SERF2; gene has intron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 581819 582847 + orf19.2966 581819 582847 1 581819 582847 581904 582662 orf19.10483|IPF24336.1|IPF7778.2|Contig4-2061_0002|orf6.6650|CA4167|CaO19.10483|CaO19.2966|IPF7778 Predicted ORF in Assemblies 19, 20 and 21; clade-associated gene expression; farnesol-downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 582904 584139 + orf19.2967 582904 584139 1 582904 584139 582959 584011 TIF34 orf19.10484|IPF24320.1|IPF7775.2|Contig4-2061_0003|orf6.6649|CA4166|CaO19.2967|CaO19.10484 Putative translation initiation factor; mutation confers hypersensitivity to roridin A and verrucarin A; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 584392 585135 + orf19.2968 584392 585135 1 584392 585135 584392 584994 IPF7774.2|IPF28910.1|Contig4-2061_0004|orf6.2121|CA4165|CaO19.2968|IPF7774|orf6.6648|IPF7774.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 585890 588603 + orf19.2969 585890 588603 1 585890 588603 585974 588532 RAD16 orf19.10486|IPF24246.1|IPF15502.2|orf6.2120|CA0917|CaO19.10486|CaO19.2969 Protein similar to S. cerevisiae Rad16p; flucytosine induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 587979 588541 - ntar_61 587979 588541 1 588541 587979 588457 588335 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 588912 593357 + orf19.2970 588912 593357 1 588912 593357 588960 593174 LYS2 orf19.10487|IPF17598.2|IPF19710.1|Contig4-1985_0002|orf6.2119|orf6.240|orf6.5719|CA0916|CaO19.2970 Large subunit of heterodimeric alpha-aminoadipate reductase; enzyme of lysine biosynthesis; contains predicted binding sites for AMP and alpha-aminoadipate; feedback inhibited by lysine or thialysine; regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 593636 595690 + orf19.2971 593636 595690 1 593636 595690 593755 595524 orf19.10488|IPF7316.2|IPF18834.2|Contig4-1985_0001|orf6.5718|CA3451|CaO19.2971|IPF7316 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 595793 596505 + ntar_62 595793 596505 1 595793 596505 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 595941 596604 - ntar_63 595941 596604 1 596604 595941 596256 596134 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 597733 600066 + orf19.2972 597733 600066 1 597733 600066 598075 599790 PDE2 orf19.10489|IPF24285.1|IPF7318.2|Contig4-2816_0009|Contig4-2816_0010|orf6.5717|CA3450|CaO19.10489|CaO19.2972 Cyclic nucleotide phosphodiesterase, high affinity; role in moderating signaling via cAMP; required for wild-type virulence, hyphal growth, switching, and cell wall, but not for pseudohyphal growth; expressed shortly after hyphal induction [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 599883 600108 - ntar_64 599883 600108 1 600108 599883 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 600575 602988 + orf19.2973 600575 602988 1 600575 602988 600742 602781 orf19.10490|IPF24265.1|IPF7320.2|Contig4-2816_0007|orf6.5716|CA3449|CaO19.2973|CaO19.10490|IPF7320 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 602764 603874 - orf19.2974 602764 603874 1 603874 602764 603791 603189 YKT6 orf19.10491|IPF24350.1|IPF7321.1|Contig4-2816_0005|orf6.5715|CA3448|CaO19.10491|CaO19.2974 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 604482 605695 + orf19.2975 604482 605695 1 604482 605695 604735 605601 YPT7 orf19.10492|IPF24331.1|IPF7322.2|Contig4-2816_0003|orf6.5714|RAB7|CA3447|YPT71|CaO19.10492|CaO19.2975|YPT70 Protein of YPT/RAB family; induced during the mating process [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 605680 606761 - orf19.2977 605680 606761 1 606761 605680 606542 605784 orf19.10494|IPF24332.1|IPF7324.2|Contig4-2816_0002|orf6.5712|CA3446|CaO19.10494|CaO19.2977|IPF7324 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 607044 607672 - orf19.2978 607044 607672 1 607672 607044 607584 607210 orf19.10495|IPF24393.1|IPF7325.1|Contig4-2816_0001|orf6.5711|CA3445|CaO19.2978|CaO19.10495|IPF7325 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 607869 610080 - orf19.2980 607869 610080 1 610080 607869 610046 607869 orf19.10497|IPF24259.1|IPF11323.2|Contig4-2816_0011|orf6.5709|CA3444|CaO19.10497|TIP39|CaO19.2980|IPF11323 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 607870 608365 + ntar_65 607870 608365 1 607870 608365 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 610168 611716 - orf19.2982 610168 611716 1 611716 610168 611697 610267 orf19.10499|IPF24299.1|IPF11324.1|Contig4-2573_0011|orf6.5707|CA3443|CaO19.2982|ATG17|CaO19.10499|IPF11324 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 611964 613216 + orf19.2983 611964 613216 1 611964 613216 611996 613108 CDC73 orf19.10500|IPF24313.1|IPF11326.2|Contig4-2573_0010|orf6.5706|CA3442|CaO19.2983|CaO19.10500|IPF11326 Protein similar to S. cerevisiae Cdc73p, which is a transcription elongation factor; cdc73 kap114 double transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 613123 614586 - orf19.2984 613123 614586 1 614586 613123 614535 613168 orf19.10501|IPF24303.1|IPF11327.1|Contig4-2573_0009|orf6.5705|CA3441|CaO19.2984|MST1|CaO19.10501 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 614674 615384 - orf19.2985 614674 615384 1 615384 614674 615281 614763 orf19.10502|IPF24360.1|IPF11328.1|Contig4-2573_0007|orf6.5704|CA3440|CaO19.10502|CaO19.2985|IPF11328 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 614761 616299 + orf19.2986 614761 616299 1 614761 616299 615529 615906 orf19.10503|IPF24392.1|IPF11329.2|Contig4-2573_0005|orf6.5703|CA3439|CaO19.10503|CaO19.2986|IPF11329 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 615875 617943 - orf19.2987 615875 617943 1 617943 615875 617788 616001 orf19.10504|IPF24281.1|IPF11330.2|Contig4-2573_0003|Contig4-2573_0004|orf6.5702|CA3438|MDM31|CaO19.10504|CaO19.2987|IPF11330 Predicted ORF in Assemblies 19, 20 and 21; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 618386 619840 + orf19.2988 618386 619840 1 618386 619840 618441 619706 orf19.10505|IPF15925.2|IPF28906.1|Contig4-2573_0001|orf6.5701|CA3437|CaO19.10505|CaO19.2988|IPF15925 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 620076 621432 + orf19.2989 620076 621432 1 620076 621432 620165 621193 orf19.10506|IPF15924.2|IPF16795.1|Contig4-2184_0001|orf6.1981|orf6.5700|CA0821|CaO19.2989|IPF16795 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 622031 624107 - orf19.2990 622031 624107 1 624107 622031 623597 622281 XOG1 orf19.10507|EXG|EXG1|IPF24307.1|IPF14073.2|Contig4-2184_0004|orf6.1982|CA0822|CaO19.2990 Exo-1,3-beta-glucanase, major exoglucanase; member of family 5 glycosyl hydrolases; affects sensitivity to inhibitors of chitin and glucan synthesis; not required for yeast-to-hyphal transition or for virulence in mouse systemic infection [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 628105 629865 + orf19.2991 628105 629865 1 628105 629865 628105 629865 HOL1 orf19.10508|IPF24277.1|IPF5592.2|Contig4-3020_0013|orf6.4874|CA2820|HOL2|CaO19.2991|CaO19.10508 Predicted ORF in Assemblies 19, 20 and 21; transcription is regulated by Nrg1p; macrophage/pseudohyphal-repressed; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 630176 630824 + orf19.2992 630176 630824 1 630176 630824 630252 630572 RPP1A orf19.10509|RP1A|CARP1A|RPA1|IPF24399.1|IPF5594.2|RPP1A-1|Contig4-3020_0012|orf6.4873|CA2819|CaO19.2992|CaO19.10509 Conserved acidic ribosomal protein, likely to be involved in regulation of translation elongation; interacts with Rpp2Bp; one of four similar C. albicans ribosomal proteins (Rpp1Ap, Rpp1Bp, Rpp2Ap, Rpp2Bp) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 630947 631742 - orf19.2994 630947 631742 1 631742 630947 631681 631073 RPL13 orf19.10511|IPF24346.1|IPF5596.2|RPL13A|Contig4-3020_0010|orf6.4871|CA2818|CaO19.2994|CaO19.10511 Protein described as ribosomal subunit; antigenic during murine systemic infection; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 632063 633483 + orf19.2994.1 632063 633483 2 632063|632490 632162|633483 632142 632897 RPS16A IPF24384.1|IPF5598.2|Contig4-3020_0009|CA2817|RPS16B|RPS16|RPS16.3 Macrophage/pseudohyphal-induced after 16 h [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 633651 634674 + orf19.2995 633651 634674 1 633651 634674 633825 634583 orf19.10512|IPF24338.1|IPF5601.2|Contig4-3020_0008|orf6.4870|CA2816|CaO19.2995|CaO19.10512|IPF5601 Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 634144 634862 - ntar_66 634144 634862 1 634862 634144 634613 634359 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 635050 638390 + orf19.2996 635050 638390 1 635050 638390 635166 638321 orf19.10513|IPF24407.1|IPF5604.2|Contig4-3020_0006|orf6.4869|CA2815|CaO19.10513|CaO19.2996|IPF5604 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 638227 639076 - orf19.2998 638227 639076 1 639076 638227 639028 638399 TSR2 orf19.10515|IPF24349.1|IPF5607.1|Contig4-3020_0003|orf6.4867|CA2814|CaO19.2998|CaO19.10515|IPF5607 Predicted ORF in Assemblies 19, 20 and 21; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 639128 641709 - orf19.3000 639128 641709 1 641709 639128 641622 639205 ORC1 orf19.10518|IPF5612.2|IPF5345.3|Contig4-3020_0001|orf6.4864|orf6.5289|CA2813|CaO19.3000 Predicted ORF in Assemblies 19, 20 and 21; essential for viability; similar to S. cerevisiae Orc1p origin recognition complex subunit [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 641830 642800 - orf19.3001 641830 642800 2 642800|642592 642671|641830 642705 642025 TEM1 orf19.10519|IPF5346.1|IPF5613.1|Contig4-3096_0001|orf6.4863|orf6.5288|CA2812|SPG1|CaO19.3001 Protein similar to S. cerevisiae Tem1p, which is a GTPase involved in termination of the M phase of the cell cycle; induced under Cdc5p depletion [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 643244 644221 + orf19.3002 643244 644221 1 643244 644221 643289 644059 RPS1 orf19.10520|RPS10|RP10|IPF5347.2|IPF28908.1|RPS1A|Contig4-3096_0003|orf6.4862|orf6.5287|CA2811|CaO19.3002|RPS3A Probable ortholog of S. cerevisiae ribosomal protein Rp10 (Rps1Ap and Rps1Bp), elicits a host antibody response during infection; transcription is induced during active growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 645044 649787 + orf19.3003 645044 649787 2 645044|645376 645182|649787 645168 649614 orf19.10521|IPF24377.1|IPF5353.2|Contig4-3096_0004|Contig4-3096_0005|orf6.5286|CA3124|IPF5353|IPF5353.3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 650079 651332 + orf19.3003.1 650079 651332 2 650079|650503 650140|651332 650129 651021 RPL6 IPF24361.1|IPF5354.2|Contig4-3096_0006|CA3123|RPL6.3 Protein similar to S. cerevisiae Rpl6p, which is a ribosomal subunit; transposon mutation affects filamentous growth; translation-related genes are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 651883 653372 + orf19.3004 651883 653372 1 651883 653372 651967 653199 orf19.10522|IPF24308.1|IPF5356.2|Contig4-3096_0008|orf6.5285|CA3122|CaO19.10522|CaO19.3004|IPF5356 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 653267 655492 - orf19.3006 653267 655492 1 655492 653267 655266 653512 orf19.10524|IPF24284.1|IPF5357.2|Contig4-3096_0010|orf6.5283|CA3121|GGA2|CaO19.10524|CaO19.3006|GGA1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 655725 656483 + orf19.3007 655725 656483 1 655725 656483 655863 656339 orf19.10525|IPF24369.1|IPF5358.2|Contig4-3096_0014|orf6.5282|CA3120|CaO19.10525|CaO19.3007|IPF5358 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 656333 657378 - orf19.3007.2 656333 657378 2 657378|657140 657231|656333 657266 656511 IPF24352.1|IPF5360.1|Contig4-3096_0015|CA3119|IPF5360|IPF5360.3 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 657452 658730 - orf19.3008 657452 658730 1 658730 657452 658608 657637 COQ4 orf19.10526|IPF24323.1|IPF5361.2|Contig4-3096_0016|orf6.5281|CA3118|CaO19.3008|CaO19.10526 Protein described as having role in coenzyme Q biosynthesis; transcriptionally induced by interaction with macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 658783 660916 - orf19.3009 658783 660916 1 660916 658783 660836 658869 orf19.10527|IPF5363|IPF24268.1|IPF5363.2|Contig4-3096_0018|orf6.5280|CA3117|CaO19.3009|CaO19.10527 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 660883 662018 + orf19.3010 660883 662018 1 660883 662018 660994 661857 orf19.10528|IPF24322.1|IPF5364.2|Contig4-3096_0019|orf6.5279|CA3116|CaO19.3010|CaO19.10528|LAB2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 662012 664570 - orf19.3010.1 662012 664570 2 664570|663452 664342|662012 664402 662242 ECM33 orf19.10528.1|ECM33.3|IPF24311.1|IPF5366.2|Contig4-3096_0020|CA3115|ECM33.3f GPI-anchored cell wall protein; mutants show cell-wall defects and reduced adhesion, host cell damage, and endocytosis; mutant infection is immunoprotective in murine model; fluconazole-induced; caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 664105 664270 + ntar_67 664105 664270 1 664105 664270 664105 664260 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 668690 672153 - orf19.3012 668690 672153 1 672153 668690 672029 668832 ARO80 orf19.10530|IPF20024.1|IPF28935.1|Contig4-3096_0034|orf6.7749|orf6.5277|CA5048|CaO19.10530|CaO19.3012|IPF20024|CA3114|IPF18384|IPF18384.1 Regulator of aromatic alcohol biosynthesis via the Ehrlich pathway; not essential for viability; similar to S. cerevisiae Aro80p, which is a transcriptional activator required for aromatic amino acid catabolism [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 672293 674003 - orf19.3013 672293 674003 2 674003|673706 673869|672293 673909 672554 CDC12 orf19.10531|IPF24312.1|IPF3714.2|Contig4-3096_0035|orf6.7750|CA5049|IPF3714 Septin; essential for viability; gene has predicted splice sites; forms ring at sites of cell division and also forms filaments in mature chlamydospore; filamentous growth induced; regulated by Nrg1p, Tup1p, tyrosol and cell density [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 674767 676855 - orf19.3014 674767 676855 2 676855|676024 676768|674767 675939 675145 BMH1 orf19.10532|IPF24334.1|IPF3712.2|Contig4-3096_0038|orf6.7751|CA5050|CaO19.10532|CaO19.3014|BMH2 14-3-3 protein, role in hyphal growth; possibly regulated by host interaction; sole 14-3-3 protein in C. albicans while S. cerevisiae has two 14-3-3 proteins; localizes to cell surface of yeast-form cells but not of hyphae; intron in 5'-UTR [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr1 677269 679206 - orf19.3015 677269 679206 1 679206 677269 679161 677467 ARX1 orf19.10533|IPF24288.1|IPF3709.1|Contig4-3096_0039|orf6.7752|CA5051|CaO19.10533|CaO19.3015|IPF3709 Predicted ORF in Assemblies 19, 20 and 21; downregulated during core stress response; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 679366 679493 + ntar_68 679366 679493 1 679366 679493 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 679763 680529 + orf19.3016 679763 680529 1 679763 680529 679856 680281 orf19.10534|IPF24371.1|IPF3708.2|Contig4-3096_0040|orf6.7753|CA5052|CaO19.3016|CaO19.10534|IPF3708 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 680212 681566 - orf19.3018 680212 681566 1 681566 680212 681533 680313 SPP1 orf19.10536|IPF24310.1|IPF3707.2|Contig4-3096_0042|orf6.7755|CA5053|CaO19.3018|CaO19.10536|IPF3707 Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide in yhb1 mutant; cell-cycle regulated periodic mRNA expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 681659 683921 + orf19.3019 681659 683921 1 681659 683921 681715 683751 orf19.10537|IPF24266.1|IPF3704.2|IPF3704|Contig4-3096_0043|orf6.7756|CA5054|CaO19.3019|CaO19.10537 Transcription may be increased in an azole-resistant strain that overexpresses MDR1 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 683882 684247 - ntar_69 683882 684247 1 684247 683882 684247 684125 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 683972 685252 + orf19.3021 683972 685252 2 683972|684073 683998|685252 683972 685176 orf19.10539|IPF24316.1|IPF3701.1|Contig4-3096_0044|orf6.7758|CA5055|IPF3701 Predicted ORF in Assemblies 19, 20 and 21; induced during planktonic growth [label_first_exon=CGD label_last_exon=CGDmod orf_changed=false scenario_first_exon=Z scenario_last_exon=F] Ca21chr1 684251 684607 - ntar_70 684251 684607 1 684607 684251 684607 684455 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 684684 685064 - ntar_71 684684 685064 1 685064 684684 684886 684764 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 685430 686498 + orf19.3022 685430 686498 1 685430 686498 685483 686415 orf19.10540|IPF24326.1|IPF3698.1|Contig4-3096_0045|orf6.7759|CA5056|RSM24|CaO19.10540|CaO19.3022|IPF3698 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 686543 688759 + orf19.3023 686543 688759 1 686543 688759 686699 688582 orf19.10541|IPF24276.1|IPF3695.1|Contig4-3096_0047|orf6.7760|CA5057|CaO19.3023|NGG1|CaO19.10541|IPF3695 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 688533 690181 - orf19.3026 688533 690181 1 690181 688533 690091 688688 MAS1 orf19.10544|IPF24301.1|IPF3692.2|Contig4-3096_0048|orf6.7763|CA5058|CaO19.10544|CaO19.3026 Predicted ORF in Assemblies 19, 20 and 21; transcription is regulated by Nrg1p; oxidative stress-induced via Cap1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 690357 691858 + orf19.3027 690357 691858 1 690357 691858 690401 691687 orf19.10545|IPF24306.1|IPF3691.2|Contig4-3096_0049|orf6.7764|CA5059|ARP7|CaO19.10545|CaO19.3027|IPF3691 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr1 691700 693499 - orf19.3029 691700 693499 1 693499 691700 693400 691892 orf19.10547|IPF24295.1|IPF3690.2|Contig4-2530_0009|orf6.7766|CA5060|EHD3|CaO19.3029|CaO19.10547|IPF3690 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 693835 695868 - orf19.3030 693835 695868 1 695868 693835 695803 694214 orf19.10548|IPF24293.1|IPF8495.2|Contig4-3098_0057|Contig4-3098_0058|orf6.7767|CA5061|ATG21|CaO19.3030|CaO19.10548|IPF8495 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 696021 697046 - orf19.3031 696021 697046 1 697046 696021 696971 696090 orf19.10549|IPF24325.1|IPF8494.2|Contig4-3098_0056|orf6.7768|CA5062|CaO19.3031|SEC62|CaO19.10549 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 697207 699517 - orf19.3034 697207 699517 1 699517 697207 699468 697600 RLI1 orf19.10552|IPF24273.1|IPF8493.1|Contig4-3098_0053|orf6.7771|CA5063|CaO19.10552|CaO19.3034|IPF8493 Member of RNase L inhibitor (RLI) subfamily of ABC family; predicted not to be a transporter [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 700408 701191 + ntar_72 700408 701191 1 700408 701191 700953 701075 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 701406 706195 + orf19.3035 701406 706195 1 701406 706195 701786 706018 orf19.10553|IPF24378.1|IPF8489.2|Contig4-3098_0051|orf6.7772|CA5064|CaO19.10553|CHD1|CaO19.3035 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 706335 708851 + orf19.3037 706335 708851 1 706335 708851 706559 708448 orf19.10555|IPF24275.1|IPF3584.2|Contig4-3098_0049|orf6.7774|CA5065|CaO19.10555|PAB1|CaO19.3037|IPF3584 Protein described as poly(A)-binding protein; regulated by Gcn4p; induced in response to amino acid starvation (3-aminotriazole treatment); rotein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 708679 708974 - ntar_73 708679 708974 1 708974 708679 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 709388 712513 + orf19.3038 709388 712513 1 709388 712513 709532 712198 TPS2 orf19.10556|IPF24244.1|IPF3588.2|Contig4-3098_0048|orf6.7775|CA5066|CaO19.3038|CaO19.10556 Trehalose-6-phosphate (Tre6P) phosphatase; mutation causes heat sensitivity, Tre6P accumulation, and decreased mouse virulence; possible drug target; two conserved phospohydrolase motifs; no human or murine homolog [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 712872 714640 + orf19.3040 712872 714640 1 712872 714640 713038 714315 EHT1 orf19.10558|IPF24309.1|IPF3589.2|Contig4-3098_0045|orf6.7777|CA5067|CaO19.10558|CaO19.3040|IPF3589 Protein similar to S. cerevisiae Eht1p; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 714464 714845 - ntar_74 714464 714845 1 714845 714464 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 715357 717601 + orf19.3041 715357 717601 1 715357 717601 715612 717561 orf19.10559|IPF24269.1|IPF3592.2|Contig4-3098_0041|orf6.7778|CA5068|CaO19.10559|CaO19.3041|IPF3592 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 717757 718670 + orf19.3042 717757 718670 1 717757 718670 717757 718581 orf19.10560|IPF24335.1|IPF3593.2|Contig4-3098_0040|orf6.7779|CA5069|CaO19.3042|CaO19.10560|IPF3593 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 719276 719380 + tn(guu)3 719276 719380 2 719276|719345 719313|719380 tN(GUU)3.2 tRNA-Asn predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 719550 721040 + orf19.3043 719550 721040 1 719550 721040 719686 720741 orf19.10561|IPF24317.1|IPF3594.2|Contig4-3098_0039|orf6.7780|CA5070|CaO19.10561|TGL2|CaO19.3043|IPF3594 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 720918 722668 - orf19.3045 720918 722668 1 722668 720918 722624 721188 orf19.10563|IPF3597|IPF24294.1|IPF3597.2|Contig4-3098_0035|orf6.7782|CA5071|ALD4|CaO19.10563|CaO19.3045 Predicted ORF in Assemblies 19, 20 and 21; virulence-group-correlated expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 723058 726898 - orf19.3047 723058 726898 1 726898 723058 726816 723187 orf19.10565|IPF24394.1|IPF3598.2|Contig4-3098_0033|orf6.7784|CA5072|CaO19.3047|SIP3|CaO19.10565|IPF3598 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 727083 730292 - orf19.3048 727083 730292 1 730292 727083 730160 727188 orf19.10566|IPF24413.1|IPF3603.2|Contig4-3098_0027|Contig4-3098_0029|Contig4-3098_0031|orf6.7785|CA5073|CaO19.3048|CaO19.10566|IPF3603 Predicted ORF in Assemblies 19, 20 and 21; transcription is repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 731103 732512 - orf19.3049 731103 732512 1 732512 731103 732512 731103 orf19.10567|IPF24302.1|IPF3607.2|Contig4-3098_0024|orf6.7786|CA5074|CaO19.10567|SPS1|CaO19.3049|IPF3607 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 732704 735876 - orf19.3050 732704 735876 1 735876 732704 735718 732842 AGE1 orf19.10568|orf6.7787|IPF24238.1|IPF3610.2|Contig4-3098_0022|CA5075|CaO19.10568|CaO19.3050|IPF3610 Protein described as a GTPase activator; transcriptionally regulated by iron; expression greater in low iron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 736661 737895 + orf19.3051 736661 737895 1 736661 737895 736864 737745 orf19.10569|IPF24324.1|IPF15301.2|Contig4-3098_0020|orf6.7788|CA5076|CaO19.3051|CaO19.10569|IPF15301 Predicted ORF in Assemblies 19, 20 and 21; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 738246 739128 + orf19.3052 738246 739128 1 738246 739128 738302 738925 YPT1 orf19.10570|IPF24344.1|IPF15299.2|Contig4-3098_0019|orf6.7789|CA5077|CaO19.10570|CaO19.3052 Functional homolog of S. cerevisiae Ypt1p, which is an essential small Ras-type GTPase involved in protein secretion at ER-to-Golgi; dominant-negative mutation causes SAP secretion defect and accumulation of intracellular secretory vesicles [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 738940 740368 - orf19.3053 738940 740368 1 740368 738940 739753 739208 orf19.10571|IPF24357.1|IPF15297.1|Contig4-3098_0017|orf6.7790|CA5078|CaO19.10571|CaO19.3053|IPF15297 Predicted ORF in Assemblies 19, 20 and 21; identified in extracts from biofilm and planktonic cells; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 740591 742178 + orf19.3054 740591 742178 1 740591 742178 740662 742107 RPN3 orf19.10572|IPF24300.1|IPF9265.2|Contig4-3098_0013|Contig4-3098_0015|orf6.7791|CA5079|CaO19.3054|CaO19.10572 Predicted ORF in Assemblies 19, 20 and 21; amphotericin B repressed; oxidative stress-induced via Cap1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 742271 744160 + orf19.3055 742271 744160 2 742271|742435 742367|744160 742294 744058 orf19.10573|IPF24291.1|IPF9268.2|Contig4-3098_0012|orf6.7792|CA5080|SRB4|IPF9268.3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 743991 744674 - orf19.3057 743991 744674 1 744674 743991 744628 744122 orf19.10575|IPF24363.1|IPF9270.1|Contig4-3098_0008|orf6.7794|ILM1|CaO19.10575|CaO19.3057 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr1 744743 744960 + ntar_75 744743 744960 1 744743 744960 744743 744874 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 744807 746468 - orf19.3058 744807 746468 1 746468 744807 746407 744965 orf19.10576|IPF24298.1|IPF9273.2|Contig4-3098_0006|orf6.7795|CA5081|CaO19.10576|COQ6|CaO19.3058 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 746647 748026 - orf19.3059 746647 748026 1 748026 746647 747828 746794 SUA71 orf19.10577|IPF24321.1|IPF9274.2|Contig4-3098_0004|orf6.7796|CA5082|CaO19.3059|CaO19.10577|SUA70 Predicted transcriptional regulator; downregulated during planktonic growth, whereas related SUA72 is induced; transcription is positively regulated by Tbf1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 748300 748415 - tl(uaa)3 748300 748415 2 748415|748345 748377|748300 tL(UAA)3.2 tRNA-Leu predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 749169 749267 + orf19.3059.1 749169 749267 1 749169 749267 [NOT TRANSCRIBED?] ORF added to Assembly 21 based on comparative genome analysis; overlaps orf19.3059.2, which is annotated as a blocked reading frame [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 749587 750716 + orf19.3060 749587 750716 1 749587 750716 749657 750484 orf19.10578|IPF24333.1|IPF9278.1|Contig4-3098_0002|orf6.7797|CA5083|CaO19.10578|SWP1|CaO19.3060|IPF9278 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 750382 751185 - orf19.3061 750382 751185 1 751185 750382 751158 750607 orf19.10579|IPF24358.1|IPF9279.1|Contig4-3098_0001|orf6.7798|CA5084|IMP1|CaO19.10579|CaO19.3061 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 751370 752645 - orf19.3061.1 751370 752645 3 752645|752195|751722 752602|752052|751370 752184 751463 orf19.3061.2|CA5086|RPS22B|CA5085|RPS22.exon2|IPF9280.2 Predicted ORF in Assembly 20 and 21; gene has intron; similar to RPS22A/orf19.6265 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr1 752785 756419 + orf19.3062 752785 756419 1 752785 756419 752851 756390 orf19.10580|IPF24395.1|IPF20025.1|Contig4-2792_0003|orf6.7799|CA5087|CaO19.3062|CaO19.10580|IPF20025 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 756245 757183 - orf19.3063 756245 757183 1 757183 756245 757150 756437 orf19.10581|IPF24342.1|IPF9758.1|Contig4-2792_0004|orf6.7800|CA5088|CaO19.10581|DPB3|CaO19.3063|IPF9758 Phosphorylated protein of unknown function; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 757268 758043 - orf19.3064 757268 758043 1 758043 757268 757871 757365 MRPL27 orf19.10582|IPF24362.1|IPF9757.1|Contig4-2792_0005|orf6.7801|CA5089|CaO19.3064|CaO19.10582 Putative ribosomal protein [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 757987 758668 + orf19.3064.1 757987 758668 1 757987 758668 758360 758599 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 758408 759754 - orf19.3065 758408 759754 1 759754 758408 759714 758629 DAO1 orf19.10583|IPF24315.1|IPF9755.2|Contig4-2792_0007|Contig4-2792_0008|orf6.7802|CA5090|CaO19.10583|CaO19.3065|IFG4 Putative D-amino acid oxidase; transcription is regulated upon yeast-hyphal switch [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 761383 765062 + orf19.3066 761383 765062 1 761383 765062 761491 764928 ENG1 orf19.10584|IPF9751.2|IPF28933.1|Contig4-2792_0015|Contig4-2792_0016|Contig4-2952_0001|orf6.7803|YNR67|ACF3|orf19.71|DSE4|CaO19.3066|CA5091 Endo-1,3-beta-glucanase required for cell separation after division, orthologous to S. cerevisiae Dse4p; caspofungin repressed; fungal-specific (no human or murine homolog); repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 765307 766648 + orf19.71 765307 766648 1 765307 766648 765540 766592 Contig4-2952_0001|CaO19.71|GRH1 Predicted ORF in Assembly 19 and 21; deleted from/reinstated in Assembly 20 (see Locus History) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 766708 766795 - tt(cgu)1 766708 766795 2 766795|766743 766760|766708 tRNA-Thr predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 767047 771005 - orf19.1133 767047 771005 1 771005 767047 771005 767142 MSB1 orf19.8726|IPF6172.3|IPF29571.1|Contig4-2952_0004|orf6.1506|CA0525|MSB1.5eoc|IPF6172.2 Predicted ORF in Assemblies 19, 20 and 21; expression in S. cerevisiae flo8 and flo11 mutants suggests a role in regulation of adhesion factors [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr1 773906 776246 - orf19.1037 773906 776246 1 776246 773906 775845 774073 orf19.8639|orf19.8640|IPF26266.1|IPF19718.1|IPF26258.1|IPF13751.2|Contig4-2664_0012|orf6.2320|orf6.2319|CA1036|CA1035|orf19.1038|CaO19.1037|CaO19.8639|IFI2.5f [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 776664 779063 - orf19.1036 776664 779063 1 779063 776664 778650 776803 MNS1 orf19.8638|IPF6163.1|IPF29592.1|Contig4-2952_0008|orf6.2321|CA1037|CaO19.8638|CaO19.1036 Alpha-1,2-mannosidase; ER form is converted by Kex2p to a cytosolic form; processes Man9GlcNAc2 to Man8GlcNAc2 isomer B; member of endoplasmic-reticulum localized glycosyl hydrolase family 47 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 780767 784208 + orf19.1035 780767 784208 1 780767 784208 781180 784023 WAR1 orf19.8637|IPF6159.2|IPF17784.3|Contig4-2952_0016|orf6.2322|orf6.265|orf6.3216|CA1038|CaO19.1035|IPF6159 Predicted zinc cluster protein involved in resistance to weak organic acids; has similarity to S. cerevisiae War1p, which is a transcription factor involved in the regulation of weak acid stress response genes [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 784433 785236 + orf19.1034 784433 785236 1 784433 785236 784529 785080 orf19.8636|IPF18786.2|IPF6156.1|Contig4-2952_0020|orf6.3217|orf6.2323|CA1625|CaO19.1034|IPF6156 Predicted ORF in Assemblies 19, 20 and 21; caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 785107 787009 - orf19.1033 785107 787009 1 787009 785107 786942 785155 STR2 orf19.8635|IPF26248.1|IPF6155.2|orf6.3218|CA1626|CaO19.1033 Protein not essential for viability; similar to S. cerevisiae Str2p, which is cystathionine gamma-synthase involved in sulfur metabolism [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 788158 790232 + orf19.1032 788158 790232 2 788158|788486 788375|790232 788364 790210 SKO1 orf19.8634|IPF26249.1|IPF6153.2|Contig4-2301_0003|Contig4-2301_0004|orf6.3219|CA1627|CaO19.8634|CaO19.1032|SKO1.3f|SKO1.3 Putative transcription factor involved in cell wall damage response, similar to S. cerevisiae Sko1p; mutation causes caspofungin sensitivity; induced by osmotic stress via Hog1p; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 790212 794208 - orf19.1031 790212 794208 1 794208 790212 793652 790431 HMG1 orf19.8633|IPF26280.1|IPF19736.1|Contig4-2301_0005|Contig4-2301_0007|Contig4-2301_0008|orf6.3220|CA1628|CaO19.1031|CaO19.8633 HMG-CoA reductase; enzyme of sterol pathway; inhibited by lovastatin; gene not transcriptionally regulated in response to lovastatin and fluconazole [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 794351 794860 + ntar_76 794351 794860 1 794351 794860 794614 794736 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 795516 796938 - orf19.1030 795516 796938 1 796938 795516 796893 795613 orf19.8632|IPF26252.1|IPF14314.2|Contig4-2064_0001|orf6.3221|CA1629|FPR3|CaO19.1030|NPI46 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 797127 798218 + orf19.1029 797127 798218 1 797127 798218 797227 798159 orf19.8631|IPF26259.1|IPF14315.2|Contig4-2010_0007|orf6.3222|CA1630|RPP1|CaO19.1029 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 798151 799429 - orf19.1028 798151 799429 1 799429 798151 799429 798251 orf19.8630|IPF19583.2|IPF19582.1|Contig4-2010_0003|Contig4-2010_0005|orf6.3223|orf6.411|CA1631|ELA1|CaO19.1028|IPF19582 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 801713 803065 + orf19.1027 801713 803065 1 801713 803065 801801 802910 PDR16 orf19.8629|IPF15777.2|IPF19201.1|Contig4-2078_0006|orf6.511|orf6.648|CA6183|CaO19.1027|PDR17 Phosphatidylinositol transfer protein; increased transcription correlates with CDR1 and CDR2 overexpression and azole resistance; induced by fluphenazine, 17-beta-estradiol, ethynyl estradiol, nitric oxide; farnesol-downregulated in biofilm [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 802911 804131 - orf19.1026 802911 804131 1 804131 802911 804068 803076 orf19.8628|IPF15779.2|IPF17757.1|Contig4-2078_0005|orf6.512|orf6.647|CA0142|CSL4|CaO19.1026 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 804217 804990 + orf19.1026.1 804217 804990 1 804217 804990 804272 804541 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 804615 805056 - ntar_77 804615 805056 1 805056 804615 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 805311 805841 + ntar_78 805311 805841 1 805311 805841 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 806429 811506 - orf19.4457 806429 811506 1 811506 806429 811506 806539 BNI4 orf19.11937|orf6.2835|IPF22779.1|IPF11847.2|Contig4-2719_0011|CA1366|CaO19.4457|CaO19.11937|IPF11847 Protein required for wild-type cell wall chitin distribution, morphology, hyphal growth; not essential; similar to S. cerevisiae Bni4p (targeting subunit for Glc7p phosphatase, involved in bud-neck localization of chitin synthase III) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr1 811835 812024 + ntar_79 811835 812024 1 811835 812024 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 812650 812939 + ntar_80 812650 812939 1 812650 812939 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 813478 813663 + ntar_81 813478 813663 1 813478 813663 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 813797 815724 - orf19.4459 813797 815724 1 815724 813797 815640 813949 orf19.11939|IPF22769.1|IPF11849.2|Contig4-2719_0006|Contig4-2719_0007|orf6.2833|YNL234W|CA1365|CaO19.4459|CaO19.11939|IPF11849 Predicted ORF in Assemblies 19, 20 and 21; similar to S. cerevisiae Ynl234wp, which is a putative heme-binding stress-related protein; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 820980 821342 - orf19.4461 820980 821342 1 821342 820980 821342 820980 orf19.11941|IPF22784.1|IPF28385.1|orf6.2028|CaO19.4461|CaO19.11941 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 823623 824693 + orf19.4463 823623 824693 1 823623 824693 823623 824693 orf19.11943|IPF14489.2|IPF19477.2|Contig4-1754_0003|orf6.2030|orf6.29|CA0856|CIS308|CaO19.4463|IFL1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 825278 826123 + orf19.4464 825278 826123 1 825278 826123 825384 825899 SEN15 orf19.11944|IPF22778.1|IPF14490.2|orf6.2031|CA0857|CaO19.11944|CaO19.4464 Similar to delta subunit of tRNA splicing endonuclease; increased transcription is observed upon fluphenazine treatment [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 825758 828223 - orf19.4465 825758 828223 1 828223 825758 828046 825995 orf19.11945|IPF22768.1|IPF14493.2|Contig4-1895_0003|orf6.2032|CA0858|CaO19.11945|CaO19.4465|IPF14493 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 828425 830135 - orf19.4466 828425 830135 1 830135 828425 830116 828572 orf19.11947|IPF14495.2|IPF17107.3|Contig4-1895_0001|orf6.2033|orf6.338|CA0859|CaO19.4466|ERF2|IPF14495|IPF14495.3|IPF14495.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 830194 832025 + orf19.4467 830194 832025 1 830194 832025 830349 831857 orf19.11948|IPF18468.2|IPF17109.2|orf6.337|orf6.4319|CA2424|CaO19.4467|IPF18468|IPF18468.1 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 832129 832932 + orf19.4468 832129 832932 1 832129 832932 832188 832697 orf19.11949|IPF19574.1|IPF19575.1|Contig4-3094_0028|orf6.336|orf6.4318|CA2423|CaO19.4468|SDH4|SDH41 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 832810 833902 - orf19.4470 832810 833902 1 833902 832810 833843 833304 IPF14997.2|IPF28381.1|orf6.4317|CA2422|CaO19.4470|IPF14997.5f|IPF14997 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 834170 837124 - orf19.4471 834170 837124 1 837124 834170 836915 834306 orf19.11951|IPF22765.1|IPF14998.2|Contig4-2170_0004|orf6.4316|CA2421|CaO19.11951|CaO19.4471|IPF14998 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 837122 837402 + ntar_82 837122 837402 1 837122 837402 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 837520 837876 + orf19.4472 837520 837876 1 837520 837876 837520 837837 orf19.11952|IPF22785.1|IPF28386.1|orf6.4315|CaO19.4472|CaO19.11952 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 838135 839080 + orf19.4473 838135 839080 1 838135 839080 838307 838834 orf19.11953|IPF22777.1|IPF15002.2|Contig4-2170_0002|orf6.4314|CA2420|CaO19.11953|SPC19|CaO19.4473 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 839111 840397 + orf19.4474 839111 840397 1 839111 840397 839354 840280 orf19.11954|IPF14379|IPF22775.1|IPF14379.2|orf6.4313|CA2419|CaO19.4474|CaO19.11954 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 840347 842011 - orf19.4475 840347 842011 1 842011 840347 841877 840435 KTR4 orf19.11955|MNT4|IPF22771.1|IPF14377.2|Contig4-2993_0007|orf6.4312|CA2418|CaO19.11955|CaO19.4475 Protein with similarity to mannosyltransferases; induced during cell wall regeneration; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 842723 843898 - orf19.4476 842723 843898 1 843898 842723 843876 842842 orf19.11957|Contig4-1934_0004|IFD1|IPF22773.1|IPF14375.2|orf6.2004|orf6.4311|CA2417|CaO19.4476|CaO19.11956|IFD6|CA0840|IPF18856.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 844704 845959 - orf19.4477 844704 845959 1 845959 844704 845857 844844 CSH1 orf6.4310|IFD4|IPF22774.1|IPF14374.2|CA2416|CAgp38|CaO19.11957|CaO19.4477 Member of aldo-keto reductase family, similar to aryl alcohol dehydrogenases; role in adhesion to fibronectin, cell surface hydrophobicity; regulated by temperature, growth phase, benomyl, macrophage interaction; azole resistance associated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 846659 848892 + orf19.4478 846659 848892 1 846659 848892 846723 848819 orf19.11958|IPF22767.1|IPF17203.2|orf6.4309|CA2415|CaO19.4478|MSD1|CaO19.11958 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 848788 851096 - orf19.4479 848788 851096 1 851096 848788 851044 848882 orf19.11959|orf19.11960|IPF22770.1|IPF22776.1|IPF13757.2|IPF13756.2|Contig4-2664_0018|Contig4-2664_0021|orf6.4308|orf6.4307|CA2414|CA2413|orf19.4480|IPF13756.3f Predicted ORF in Assemblies 19, 20 and 21; downregulated during core stress response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 851871 852302 - orf19.4481 851871 852302 1 852302 851871 852302 851871 MFALPHA orf19.11961|orf6.4306|MFalpha1|IPF22780.1|IPF13755.1|MF1|Contig4-2664_0016|CA2412|CaO19.11961|CaO19.4481|IPF13755 Alpha factor mating pheromone precursor; three copies of pheromone that are proteolytically processed by Kex2p and possibly by Orf19.5851p; required for alpha cells to mate; expressed specifically in opaque phase MTLalpha/MTLalpha cells [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 854018 855784 + orf19.4482 854018 855784 1 854018 855784 854018 855784 IFI3 orf19.11962|orf19.11963|IPF22783.1|IPF19949.1|Contig4-2664_0012|orf6.4304|orf6.4305|CA2411|orf19.4483 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21; constitutive expression independent of MTL or white-opaque status [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 855759 857193 - orf19.1039 855759 857193 2 857193|857035 857120|855759 857122 855932 orf19.8641|IPF17890.1|IPF29595.1|Contig4-2664_0010|orf6.2318|CA1034|BET4.3f|BET4.exon2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 857264 858081 + orf19.1040 857264 858081 1 857264 858081 857326 857970 MAD2 orf19.8642|IPF17891.2|IPF17882.3|Contig4-2664_0009|orf6.2122|orf6.2317|CA1033|CaO19.1040 Protein required for the spindle assembly checkpoint of the cell cycle; necessary for survival in host cell macrophages and for virulence in a mouse model of systemic candidiasis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 857780 859468 - orf19.1041 857780 859468 1 859468 857780 859468 857981 orf19.8643|IPF26251.1|IPF17881.2|Contig4-2664_0008|orf6.2123|CA0918|CaO19.1041|CaO19.8643|IPF17881 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 859474 860615 - orf19.1042 859474 860615 1 860615 859474 860544 859696 POR1 orf19.8644|IPF26262.1|IPF12994.2|Contig4-2664_0006|orf6.2124|CA0919|VDAC1|CaO19.1042 Mitochondrial outer membrane porin; in detergent-resistant membrane fraction (possible lipid raft component); antigenic in human, mouse; flucytosine-, macrophage-, farnesol- induced; fluconazole, caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 860757 863028 + orf19.1043 860757 863028 1 860757 863028 862110 863027 orf19.8645|IPF26261.1|IPF12992.2|orf6.2125|CA0921|CaO19.1043|CaO19.8645|IPF12992 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 860833 861445 - ntar_83 860833 861445 1 861445 860833 861245 861084 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 861585 862000 - ntar_84 861585 862000 1 862000 861585 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 862989 864150 - orf19.1045 862989 864150 1 864150 862989 864150 863089 orf19.8647|IPF26260.1|IPF12991.1|Contig4-2647_0003|orf6.2127|CA0922|CaO19.8647|IST3|CaO19.1045|IPF12991 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 864056 866828 + orf19.1047 864056 866828 1 864056 866828 864198 866747 ERB1 orf19.8649|IPF26243.1|IPF12987.2|Contig4-2647_0005|Contig4-2647_0006|orf6.2129|CA0923|CaO19.1047|IPF12987 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); hyphal repressed; macrophage repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 867415 868563 + orf19.1048 867415 868563 1 867415 868563 867455 868489 IFD6 orf19.8650|Contig4-2647_0009|YPX98|YPL88|IFD1|IPF18856.2|IPF17049.2|Contig4-2647_0010|orf6.2004|orf6.2130|CA0924|CaO19.1048|LPG20|IFD5 Aldo-keto reductase family member; similar to aryl alcohol dehydrogenases, S. cerevisiae Ypl088wp; increased protein correlates with MDR1 overexpression (but not CDR1 or CDR2) in fluconazole-resistant clinical isolates; farnesol regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 868476 869284 - orf19.1049 868476 869284 1 869284 868476 869162 868578 orf19.8651|IPF18855.2|IPF17050.1|Contig4-2647_0011|orf6.2131|CA0925|CaO19.1049|CaO19.8651|IPF17050 Predicted ORF in Assemblies 19, 20 and 21; expression upregulated during planktonic growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 869210 869499 + ntar_85 869210 869499 1 869210 869499 869210 869353 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 869361 870467 - orf19.1050 869361 870467 1 870467 869361 870400 869498 orf19.8652|IPF15638.2|IPF17051.3|Contig4-2647_0015|orf6.2006|orf6.2132|CA0841|CaO19.1050|IPF15638 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 870595 871225 - orf19.1051 870595 871225 1 871225 870595 871141 870746 HTA2 orf19.8653|IPF26275.1|IPF15637.2|Contig4-2647_0017|orf6.2007|CaO19.1051|CaO19.8653 Protein described as histone H2A; farnesol regulated; transcription is downregulated in both intermediate and mature biofilms [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 871950 872689 + orf19.1052 871950 872689 1 871950 872689 872008 872400 orf19.8654|IPF26276.1|IPF15634.2|Contig4-2647_0021|orf6.2008|HTB2|CaO19.1052|CaO19.8654 Predicted histone H2B [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 872475 873905 - orf19.1053 872475 873905 1 873905 872475 873841 872669 orf19.8655|IPF26257.1|IPF15633.2|Contig4-2647_0022|orf6.2009|CA0842|CaO19.8655|BST1|CaO19.1053|IPF15633 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 874058 874432 + ntar_86 874058 874432 1 874058 874432 874074 874229 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 874659 875581 - orf19.1054 874659 875581 1 875581 874659 875468 874659 orf19.8656|IPF18853.1|IPF16097.3|Contig4-2647_0024|orf6.2010|orf6.4935|CA0843|CaO19.1054|IPF18853 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 876382 878066 - orf19.1055 876382 878066 2 878066|877746 877857|876382 877866 876470 CDC3 orf19.8657|IPF16098.2|IPF29594.1|Contig4-2089_0009|orf6.2011|orf6.4934|CA0844 Septin; essential for viability; functional homolog of S. cerevisiae Cdc3p; down-regulation associated with azole resistance; macrophage/pseudohyphal-repressed; virulence-group-correlated expression; gene has intron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 878711 879534 - orf19.1057 878711 879534 1 879534 878711 879384 878815 orf19.8659|IPF26268.1|IPF17234.2|Contig4-2089_0004|Contig4-2089_0005|orf6.4932|CA2864|CaO19.1057|CaO19.8659|IPF17234.3f|IPF17234.3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 879598 880967 + orf19.1058 879598 880967 2 879598|880323 880175|880967 879709 880689 orf19.8660|IPF26270.1|IPF20117.1|Contig4-2089_0002|orf6.4931|CA2863|IPF20117 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 880839 881402 - orf19.1059 880839 881402 1 881402 880839 881330 881013 HHF1 orf19.8661|HHF21|IPF26279.1|IPF7050.1|HHF2|Contig4-1791_0006|orf6.4930|orf6.5621|CA2862|CaO19.1059|CaO19.8661 Putative histone H4; reduced mRNA in homozygous fkh2 null mutant; regulated by Efg1p; fluconazole induced; amphotericin B repressed; farnesol regulated; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 881425 881950 - orf19.1060 881425 881950 1 881950 881425 881950 881441 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 882020 882836 + orf19.1061 882020 882836 1 882020 882836 882239 882649 HHT21 orf19.8663|IPF26271.1|IPF7053.2|HHT2|Contig4-1791_0001|orf6.4928|orf6.5620|CA2861|CaO19.8663|HHT1|CaO19.1061 Putative histone H3; amphotericin B repressed; regulated by Efg1p; farnesol regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 882993 884228 - orf19.1062 882993 884228 1 884228 882993 884228 882993 orf19.8664|IPF26254.1|IPF7054.1|Contig4-1791_0008|orf6.4927|CA2860|HRQ1|CaO19.8664|CaO19.1062|IPF7054 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 884332 885852 - orf19.1063 884332 885852 1 885852 884332 885808 884624 orf19.8665|IPF26256.1|IPF7056.2|Contig4-1738_0001|orf6.4926|CA2859|FMP44|CaO19.1063|CaO19.8665|IPF7056 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 885974 889261 - orf19.1064 885974 889261 2 889261|888113 889191|885974 889191 886084 ACS2 orf19.8666|IPF26246.1|IPF7057.2|Contig4-2199_0001|orf6.4925|CA2858|CaO19.8666|CaO19.1064 Probable acetyl-CoA synthetase, similar to known fungal acetyl-CoA synthetases; antigenic during murine systemic infection; antigenic in human; upregulated by Efg1p; macrophage-induced protein; soluble protein in hyphae [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 888611 889256 + ntar_87 888611 889256 1 888611 889256 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 889411 890359 + ntar_88 889411 890359 1 889411 890359 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 890350 892425 - orf19.1065 890350 892425 1 892425 890350 892386 890449 SSA2 orf19.8667|HS72|SSA1|IPF26247.1|IPF7060.2|Contig4-2688_0006|Contig4-2688_0009|orf6.4924|CA2857|CaO19.1065|CaO19.8667 HSP70 family chaperone; antigenic; role in sensitivity to, import of beta-defensin peptides; ATPase domain binds histatin 5; at surface of hyphae, but not yeast-form cells; farnesol-downregulated in biofilm; caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 892794 893010 + ntar_89 892794 893010 1 892794 893010 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 892889 893973 - orf19.1066 892889 893973 1 893973 892889 893750 892986 orf19.8668|IPF26264.1|IPF7062.2|Contig4-2688_0004|orf6.4923|CA2856|CaO19.8668|CaO19.1066|IPF7062 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 895068 896097 + orf19.1067 895068 896097 1 895068 896097 895168 895953 GPM2 orf19.8669|IPF26265.1|IPF7065.1|GPM1-2|Contig4-2688_0002|orf6.4922|CA2855|CaO19.1067|CaO19.8669 Protein described as phosphoglycerate mutase; decreased expression in hyphae compared to yeast-form cells; macrophage/pseudohyphal-repressed; induced by high levels of peroxide stress, farnesol-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 897633 899996 + orf19.1069 897633 899996 1 897633 899996 898013 899623 RPN4 orf19.8671|IPF26253.1|IPF7070.2|Contig4-2688_0001|Contig4-2992_0023|orf6.4920|CA2854|CaO19.1069 DNA binding protein with Cys2-His2 zinc-finger; putative regulator of proteasome genes; DNA recognition sequence (GAAGGCAAAA) enriched in regions upstream of proteasome genes; induced in core stress response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 899958 901500 - orf19.1070 899958 901500 1 901500 899958 901156 900062 orf19.8672|IPF26255.1|IPF17057.2|Contig4-2882_0025|orf6.4919|CA2853|CaO19.1070|CaO19.8672|IPF17057 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr1 901506 904112 - orf19.5203 901506 904112 1 904112 901506 903994 901625 orf19.8673|orf19.12670|IPF26263.1|IPF17059.3|IPF7581.3|IPF19744.1|Contig4-2882_0023|orf6.3419|orf6.627|orf6.4918|CA1769|orf19.1071|CaO19.5203|IPF7581.5eoc|IPF7581 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 905022 905647 - orf19.5201.1 905022 905647 1 905647 905022 905590 905339 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 905978 906648 - orf19.5201 905978 906648 1 906648 905978 906625 906023 orf19.12668|IPF22029.1|IPF7585.2|Contig4-2882_0015|Contig4-2882_0016|orf6.3417|CA1768|CaO19.12668|RSM18|CaO19.5201|IPF7585 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 906881 908629 + orf19.5200 906881 908629 1 906881 908629 907197 908141 SIT4 orf19.12667|IPF22025.1|IPF7586.1|Contig4-2882_0013|orf6.3416|CA1767|CaO19.5200|CaO19.12667 Serine/threonine protein phosphatase catalytic subunit; has a role in cell wall maintenance, hyphal growth, and virulence in a mouse systemic infection model [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 908512 910887 - orf19.5198 908512 910887 1 910887 908512 910860 908635 NOP4 orf19.12665|IPF22023.1|IPF7589.1|Contig4-2882_0011|orf6.3414|CA1766|CaO19.12665|CaO19.5198 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); downregulated in core stress response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 911127 914393 - orf19.5197 911127 914393 2 914393|913778 914224|911127 914393 911174 APE2 orf19.12664|IPF22021.1|IPF7593.2|Contig4-2882_0008|Contig4-2882_0010|orf6.3413|CA1765|CaO19.5197|CaO19.12664 Neutral arginine-, alanine-, leucine-specific metallo-aminopeptidase; expected to be secreted, purified from cell wall and intracellular fractions; protein repressed during the mating process; Hog1p-, farnesol-induced [label_first_exon=CGD label_last_exon=CGDmod orf_changed=false scenario_first_exon=Z scenario_last_exon=A] Ca21chr1 914491 915178 - orf19.5196 914491 915178 1 915178 914491 915137 914604 ESS1 orf19.12663|PIN1|IPF22030.1|IPF7596.1|Contig4-2882_0006|orf6.3412|CA1764|CaO19.5196|CaO19.12663|IPF7596 Prolyl isomerase (parvulin class); essential; involved in yeast-hyphal switching, Cph1p pathway; has inflexible linker between WW and isomerase domains, unlike human homolog; functional homolog of S. cerevisiae Ess1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 915250 916233 - orf19.5195 915250 916233 1 916233 915250 916169 915330 orf19.12662|IPF22026.1|IPF7599.1|Contig4-2882_0004|orf6.3411|CA1763|CaO19.12662|URA6|CaO19.5195 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 916433 917397 - orf19.5194.1 916433 917397 2 917397|917226 917292|916433 917328 916502 IPF22027.1|IPF19928.1|Contig4-2882_0003|CA1762|IPF20014 ORF Predicted by Annotation Working Group; clade-associated gene expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 916866 917234 + orf19.6833.2 916866 917234 1 916866 917234 916866 917234 IPF20285.1|IPF20014.1|Contig4-1399_0001 [NOT TRANSCRIBED?] ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 917406 918528 - orf19.6837 917406 918528 2 918528|918280 918352|917406 918388 917556 FMA1|orf19.12660|orf19.14127|IPF7602|IPF22028.1|IPF7602.3|IPF20284.1|IPF3538.2|Contig4-1399_0002|Contig4-2882_0001|Contig4-3051_0002|orf6.3409|orf6.6986|CA1761|orf19.5193|CaO19.6837|CaO19.14127 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 918735 919674 - orf19.6838 918735 919674 1 919674 918735 919619 918810 orf19.14128|IPF20283.1|IPF3537.1|Contig4-3051_0004|orf6.6987|CA4442|CaO19.14128|CaO19.6838|IPF3537 Putative protein of unknown function, transcription is upregulated in clinical isolates from HIV+ patients with oral candidiasis; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 918900 919355 + ntar_90 918900 919355 1 918900 919355 919044 919211 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 920040 920788 - orf19.6840 920040 920788 1 920788 920040 920753 920232 orf19.14130|IPF20288.1|IPF3535.2|Contig4-3051_0005|orf6.6989|CA4443|CaO19.14130|CaO19.6840|IPF3535 Predicted ORF in Assemblies 19, 20 and 21; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 921713 926089 - orf19.6842 921713 926089 1 926089 921713 925975 921782 orf19.14132|IPF20294.1|IPF3533.2|Contig4-3051_0008|Contig4-3051_0009|orf6.6991|CA4444|TUS1|CaO19.6842|IPF3533 Predicted ORF in Assemblies 19, 20 and 21; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 926882 928167 + orf19.6843 926882 928167 1 926882 928167 926944 928065 orf19.14133|IPF20278.1|IPF3530.2|Contig4-3051_0013|orf6.6992|CA4445|CaO19.6843|CaO19.14133|IPF3530 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 929053 930983 + orf19.6844 929053 930983 1 929053 930983 929160 930812 ICL1 orf19.14134|IPF20271.1|IPF3527.1|Contig4-3051_0014|Contig4-3051_0015|orf6.6993|CA4446|CaO19.6844|CaO19.14134 Isocitrate lyase; enzyme of glyoxylate cycle; required for wild-type virulence in murine systemic infection; no mammalian homolog; gene induced upon phagocytosis by macrophage; farnesol regulated; Pex5p-dependent peroxisomal localization [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 931169 932770 + orf19.6845 931169 932770 1 931169 932770 931252 932691 orf19.14135|IPF20274.1|IPF3523.2|Contig4-3051_0016|orf6.6994|CA4447|CaO19.14135|CaO19.6845|IPF3523 Putative transcription factor with bZIP DNA-binding motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 932618 933971 - orf19.6846 932618 933971 2 933971|933802 933882|932618 933901 932824 PHO85 orf19.14136|IPF20279.1|IPF3522.2|Contig4-3051_0017|orf6.6995|CA4448 Functional homolog of S. cerevisiae Pho85p, which is a cyclin-dependent kinase that regulates processes including transcription of PHO genes involved in phosphate metabolism; gene has intron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 934066 935851 - orf19.6847 934066 935851 1 935851 934066 935776 934217 orf19.14137|IPF20277.1|IPF3520.2|Contig4-3051_0018|orf6.6996|CA4449|IPF3520 Predicted ORF in Assemblies 19, 20 and 21; virulence-group-correlated expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 936043 939060 - orf19.6848 936043 939060 1 939060 936043 938988 936148 VPS16 orf19.14138|IPF20257.1|IPF3518.1|IPF3518|Contig4-3051_0021|orf6.6997|CA4450|VAM9|CaO19.6848|CaO19.14138 Protein similar to S. cerevisiae Vps16p, which is involved in protein-vacuolar targeting; likely to be essential for growth, based on insertional mutagenesis; downregulated in biofilm or in azole-resistant strain that overexpresses MDR1 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 939148 939559 + orf19.6849 939148 939559 1 939148 939559 939235 939537 ELC1 orf19.14139|IPF20300.1|IPF3516.1|Contig4-3051_0022|orf6.6998|CA4451|CaO19.6849|CaO19.14139 Transcription is regulated by Nrg1p and Mig1p; regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 939951 941861 + orf19.6850 939951 941861 1 939951 941861 940083 941816 orf19.14140|IPF3514|IPF20269.1|IPF3514.2|Contig4-3051_0023|orf6.6999|CA4452|CaO19.6850|RMD5|CaO19.14140 Putative transcription factor with C3HC4 zinc finger DNA-binding motif; not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 941869 943475 - orf19.6851 941869 943475 1 943475 941869 943413 942016 CHL4 orf19.14141|IPF20273.1|IPF15162.2|Contig4-3051_0024|orf6.7000|CA4453|CaO19.14141|CaO19.6851 Protein described as having role in chromosome segregation; RNA abundance regulated by tyrosol and cell density [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 943616 944862 - orf19.6852 943616 944862 1 944862 943616 944536 943709 orf19.14142|IPF20280.1|IPF15160.2|Contig4-2659_0014|orf6.7001|CA4454|CaO19.14142|CaO19.6852|IPF15160 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 946111 946921 + orf19.6852.1 946111 946921 1 946111 946921 946320 946508 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 947524 948677 - orf19.6853 947524 948677 1 948677 947524 948645 947608 orf19.14143|IPF8455.2|IPF8454.2|Contig4-2659_0010|orf6.7002|CA4455|CaO19.14143|CaO19.6853|IPF8454 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 949337 951659 + orf19.6854 949337 951659 3 949337|949763|950120 949474|949905|951659 949400 951542 ATP1 orf19.14144|orf6.7003|IPF20276.1|IPF8460.2|Contig4-2659_0004|CA4456|CA4457|ATP1.exon3|ATP1.exon2|IPF8458.1|orf19.6853.3 Protein similar to alpha subunit of ATP synthase; antigenic in human, mouse; at surface of hyphae, not yeast-form; soluble protein in hyphae; induced by ciclopirox olamine, ketoconazole, or flucytosine; downregulated by Efg1p, caspofungin [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 952222 954303 + orf19.6855 952222 954303 1 952222 954303 952391 954121 orf19.14145|IPF20270.1|IPF8464.2|Contig4-2659_0001|orf6.7004|CA4458|CaO19.6855|IPF8464 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 954057 957837 - orf19.783 954057 957837 1 957837 954057 957758 954267 orf19.8405|IPF26542.1|IPF10810.3|orf6.4113|CA2277|CaO19.8405|NEO1|CaO19.783|DRS21.5eoc|DRS21|IPF10810.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 958746 960945 + orf19.782 958746 960945 1 958746 960945 958856 960817 orf19.8404|IPF26517.1|IPF10806.2|Contig4-2404_0004|orf6.4114|CA2278|CaO19.782|CaO19.8404|IPF10806 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 962001 964178 + orf19.781 962001 964178 1 962001 964178 962001 964178 orf19.8403|IPF26516.1|IPF10804.2|Contig4-2404_0008|orf6.4115|DUR3|CA2279|CaO19.8403|DUR31|CaO19.781 Putative urea transporter; fungal-specific (no human or murine homolog) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr1 965108 970720 + orf19.780 965108 970720 1 965108 970720 965238 970679 DUR1,2 orf19.8402|IPF26532.1|IPF9766.2|Contig4-2697_0006|Contig4-2697_0007|orf6.4116|CA2280|CaO19.780|DUR1|2|CaO19.8402|"DUR1|2" Urea amidolyase, contains urea carboxylase and allophanate hydrolase activities needed to hydrolyze urea to CO2; required for utilization of urea as nitrogen source and for hyphal switch in macrophages; transcription is regulated by Nrg1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 968672 969572 - ntar_91 968672 969572 1 969572 968672 969065 968943 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 969897 970202 - ntar_92 969897 970202 1 970202 969897 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 970439 970609 - ntar_93 970439 970609 1 970609 970439 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 970929 972357 + orf19.779 970929 972357 1 970929 972357 970989 972230 HAT1 orf19.8401|IPF19108.2|IPF9767.2|Contig4-2697_0005|orf6.4117|orf6.894|CA2281|CaO19.779 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 972556 972824 - ntar_94 972556 972824 1 972824 972556 972711 972556 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 972925 973053 - ntar_95 972925 973053 1 973053 972925 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 973505 974851 + orf19.778 973505 974851 1 973505 974851 973551 974477 PIL1 orf19.8400|orf6.893|EBP1|IPF26526.1|IPF9770.2|Contig4-2697_0002|CA6179|CaO19.778|SLB1|CaO19.8400|IPF9770 Echinocandin-binding protein; localizes to cell surface of hyphae, but not yeast-form cells; biofilm induced; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 975036 976943 - orf19.776 975036 976943 1 976943 975036 976943 975036 orf19.8398|IPF26519.1|IPF3875.3|Contig4-2653_0014|orf6.1672|orf6.891|CA0630|SPO69|CaO19.776|IPF3875|IPF3875.5eoc|IPF3875.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 977189 980171 - orf19.775 977189 980171 1 980171 977189 980005 977270 orf19.8397|IPF26510.1|IPF3876.2|Contig4-2653_0010|Contig4-2653_0011|orf6.1671|CA0629|CaO19.775|CaO19.8397|IPF3876 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 980293 981672 - orf19.773 980293 981672 1 981672 980293 981250 980663 orf19.8395|orf6.1669|IPF17412.3|IPF3878.2|Contig4-2653_0008|orf6.1014|CA0628|CaO19.773|IPF3878 Putative ortholog of S. cerevisiae Rsa3p, which is a nucleolar protein involved in maturation of pre-60S ribosomal particles that interacts with Dbp6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 981949 982540 + orf19.772.1 981949 982540 1 981949 982540 982240 982461 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 982476 983956 - orf19.772 982476 983956 1 983956 982476 983901 982615 LYS21 orf19.8394|IPF3880.2|IPF16113.3|LYS22|Contig4-2653_0004|orf6.1013|orf6.3672|CA0261|CaO19.772|LYS212 Putative homocitrate synthase of lysine biosynthesis; expression is increased in a fluconazole-resistant isolate; shows colony morphology-related gene regulation by Ssn6p; ketoconazole-repressed; regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 984689 985993 + orf19.771 984689 985993 1 984689 985993 984797 985843 LPG20 orf19.8393|YPL088|IFD2|IPF16116.2|IPF3883.2|Contig4-2653_0002|orf6.1012|orf6.3671|CA1959|CaO19.771 Protein of aldo-keto reductase family; nonessential; similar to aryl alcohol dehydrogenases, S. cerevisiae Ypl088wp, A. tumefaciens MocA; osmotic stress-induced, correlates with overexpression of MDR1 in fluconazole-resistant isolate [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 986188 987602 + orf19.769 986188 987602 1 986188 987602 986332 987516 IFE1 orf19.8391|IPF16118.2|IPF3885.2|orf6.1009|orf6.1010|orf6.3669|CA1958|YAL061|BDH1|CaO19.769 Protein not essential for viability; similar to S. cerevisiae Yal061wp, which is a putative polyol dehydrogenase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 987472 990585 - orf19.768 987472 990585 1 990585 987472 990557 987594 SYG1 orf19.8389|IPF16589.3|IPF3887.2|Contig4-2869_0003|orf6.3668|orf6.698|CA1957|CaO19.768|IPF3887 Protein not essential for viability; similar to S. cerevisiae Syg1p, which is a plasma membrane protein that may be involved in signal transduction [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 991160 991402 + ntar_96 991160 991402 1 991160 991402 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 991290 993278 - orf19.767 991290 993278 1 993278 991290 992851 991691 ERG3 orf19.8387|IPF16592.2|IPF3890.1|Contig4-1987_0003|orf6.3667|orf6.696|CA1956|CaO19.8387|CaO19.767 C-5 sterol desaturase; introduces C-5(6) double bond into episterol in ergosterol biosynthesis; clinically-isolated homozygous null mutants show azole resistance, defects in hyphal growth and virulence; Efg1p-repressed; fluconazole-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 994161 997161 - orf19.764 994161 997161 1 997161 994161 997102 994445 orf19.8384|orf19.8385|IPF26522.1|IPF26525.1|IPF3897.2|IPF18581.1|Contig4-2890_0002|Contig4-2890_0003|Contig4-2890_0004|orf6.3664|orf6.3665|CA1954|CA1955|orf19.765|IPF3897.5f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 997283 998122 + orf19.763 997283 998122 1 997283 998122 997365 998039 orf19.8383|IPF26528.1|IPF3899.1|Contig4-2890_0005|orf6.3663|CA1953|CaO19.763|CBC2|CaO19.8383|IPF3899 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 998186 1000297 - orf19.762 998186 1000297 1 1000297 998186 1000297 998186 orf19.8382|IPF26518.1|IPF3901.2|Contig4-2890_0006|orf6.3662|CA1952|CaO19.8382|ASM4|CaO19.762|IFP1 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1001612 1003951 + orf19.761 1001612 1003951 1 1001612 1003951 1001683 1003809 TCO89 orf19.8381|IPF18586.1|IPF3902.3|Contig4-2890_0009|orf6.3640|orf6.3661|CA1933|CaO19.761|IPF18586 Protein described as a homolog of S. cerevisiae Tco89p, which is a component of the TOR C1 complex that is involved in the regulation of growth and cell wall integrity; heterozygous null mutant displays sensitivity to rapamycin [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1003815 1004351 - orf19.760 1003815 1004351 1 1004351 1003815 1004351 1003980 orf19.8380|IPF26539.1|IPF3903.2|Contig4-2890_0010|orf6.3639|CA1932|GON5|CaO19.8380|CaO19.760|IPF3903 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 1004493 1007435 + orf19.759 1004493 1007435 1 1004493 1007435 1004536 1007346 orf19.8379|IPF26509.1|IPF3905.2|Contig4-2890_0011|orf6.3638|CA1931|SEC21|CaO19.759|CaO19.8379|IPF3905 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1007312 1007882 - orf19.758 1007312 1007882 1 1007882 1007312 1007882 1007511 orf19.8378|IPF26529.1|IPF3906.1|Contig4-2890_0012|orf6.3637|CA1930|CaO19.8378|CaO19.758|IPF3906.3f|IPF3906.3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1008273 1008549 - orf19.757.1 1008273 1008549 1 1008549 1008273 1008446 1008273 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1008926 1011733 + orf19.757 1008926 1011733 1 1008926 1011733 1009021 1011591 orf19.8377|IPF26511.1|IPF3908.3|Contig4-2890_0014|Contig4-2890_0016|orf6.319|orf6.3636|CA0049|CaO19.757|IPF3908|IPF3908.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1012846 1014905 + orf19.756 1012846 1014905 1 1012846 1014905 1013057 1014823 SAP7 orf19.8376|IPF19935.1|IPF29700.1|Contig4-2608_0006|orf6.3635|CA1929|CaO19.8376|CaO19.756 Member of the secreted aspartyl proteinase family; expression detected during human oral infection; regulated by Ssn6p; role in murine intravenous infection; induced during, but not required for, murine vaginal infection [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1014980 1015587 - orf19.755 1014980 1015587 1 1015587 1014980 1015525 1015163 MRPL37 orf19.8375|IPF26538.1|IPF13404.1|Contig4-2000_0004|orf6.3634|CA1928|CaO19.755|CaO19.8375 Predicted ORF in Assemblies 19, 20 and 21; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1015803 1017105 + orf19.754 1015803 1017105 1 1015803 1017105 1015852 1017042 YBN5 orf19.8374|IPF26524.1|IPF13405.2|Contig4-2000_0001|Contig4-2000_0003|orf6.3633|CA1927|CaO19.754|CaO19.8374 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1017567 1020268 + orf19.753 1017567 1020268 1 1017567 1020268 1017748 1020039 orf19.8373|IPF13407.2|IPF29699.1|Contig4-2145_0002|orf6.3632|CA1926|IPF13407 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1019004 1019515 - ntar_97 1019004 1019515 1 1019515 1019004 1019208 1019068 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1019840 1021398 - orf19.752 1019840 1021398 1 1021398 1019840 1021152 1020193 orf19.8372|IPF18587.2|IPF13408.2|Contig4-2145_0003|orf6.3631|orf6.499|CA1925|CaO19.752|IPF18587|IPF18587.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1021587 1022435 - orf19.751 1021587 1022435 1 1022435 1021587 1022435 1021734 orf19.8371|IPF26527.1|IPF13409.2|Contig4-2145_0005|orf6.500|CA0096|CaO19.751|CaO19.8371|IPF13409|IPF13409.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 1021697 1022240 + ntar_98 1021697 1022240 1 1021697 1022240 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1023282 1023818 - orf19.750 1023282 1023818 1 1023818 1023282 1023818 1023282 orf19.8370|IPF26531.1|IPF15177.2|Contig4-1816_0001|orf6.1207|CA0365|CaO19.750|CaO19.8370|IPF15177 Predicted ORF in Assemblies 19, 20 and 21; exogenously expressed protein is a substrate for Kex2p processing in vitro; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1024839 1025118 - ntar_99 1024839 1025118 1 1025118 1024839 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1028014 1032719 - orf19.48 1028014 1032719 1 1032719 1028014 1032522 1028341 orf19.7710|orf19.8369|orf6.534|IPF17790.3|IPF29973.1|IPF26514.1|IPF17515.2|Contig4-1613_0005|orf6.202|orf6.1208|CA0030|CA0103|orf19.749|IPF17790.5eoc|IPF17790|IPF17790.2 Predicted ORF in Assemblies 19, 20 and 21; likely to be essential for growth, based on an insertional mutagenesis strategy; virulence-group-correlated expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 1033784 1035958 - orf19.50 1033784 1035958 1 1035958 1033784 1035890 1033908 orf19.7711|IPF27199.1|IPF11181.2|Contig4-2627_0007|orf6.4556|CA2601|CaO19.50|CaO19.7711|IPF11181 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1033908 1034142 + ntar_100 1033908 1034142 1 1033908 1034142 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1036817 1041036 + orf19.51 1036817 1041036 1 1036817 1041036 1036865 1040956 orf19.7712|IPF27203.1|IPF11177.2|Contig4-2627_0005|orf6.4555|CA2600|CLU1|CaO19.7712|CaO19.51|IPF11177 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1041891 1044002 - orf19.52 1041891 1044002 1 1044002 1041891 1043587 1042025 orf19.7713|IPF27200.1|IPF11176.2|Contig4-2627_0002|orf6.4554|CA2599|CaO19.52|MMT1|CaO19.7713|IPF11176 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1044139 1045645 - orf19.53 1044139 1045645 1 1045645 1044139 1045557 1044424 orf19.7714|IPF27201.1|IPF13142.2|Contig4-2469_0006|orf6.4553|CA2598|CaO19.53|UAF22|CaO19.7714|IPF13142 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1048035 1050539 + orf19.54 1048035 1050539 1 1048035 1050539 1048370 1050334 RHD1 orf19.7715|IPF27198.1|IPF13148.2|Contig4-2469_0001|orf6.4552|CA2597|BMT2|WRY7|CaO19.7715|CaO19.54|IFQ3 Putative beta-mannosyltransferase, required for the addition of beta-mannose to the acid-labile fraction of cell wall phosphopeptidomannan; member of a 9-gene family; transcriptionally regulated on yeast-hyphal and white-opaque switches [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1050374 1051742 - orf19.55 1050374 1051742 1 1051742 1050374 1051487 1050513 orf19.7716|IPF19547.2|IPF19546.1|orf6.4551|orf6.56|CA2596|CaO19.55|IPF19546 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1051980 1053940 - orf19.56 1051980 1053940 1 1053940 1051980 1053794 1052052 ARG2 orf19.7717|IPF19457.2|IPF12823.1|Contig4-2475_0007|orf6.4550|orf6.57|CA2595|CaO19.56 Putative enzyme of arginine biosynthesis; transcription of genes of arginine biosynthesis pathway, except for ARG2, is induced upon phagocytosis by macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1054013 1054892 - orf19.57 1054013 1054892 2 1054892|1054653 1054738|1054013 1054857 1054162 PSF2 orf19.7718|IPF27202.1|IPF12824.1|Contig4-2475_0005|orf6.4549|CA2594|CaO19.57|IPF12824 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1055273 1057832 - orf19.58 1055273 1057832 1 1057832 1055273 1057731 1055371 RRP6 orf19.7719|IPF19452.2|IPF12827.2|Contig4-2475_0001|orf6.4548|orf6.74|CA2593|CaO19.58 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1057940 1059376 + orf19.59 1057940 1059376 1 1057940 1059376 1058028 1059233 REI1 orf19.7720|IPF12828.3|IPF18447.1|orf6.4547|orf6.73|CA2592|CaO19.59|IPF18447 Predicted ORF in Assemblies 19, 20 and 21; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1059206 1062020 - orf19.4064 1059206 1062020 1 1062020 1059206 1061940 1059283 GPI7 orf19.7721|orf19.11547|IPF23187.1|IPF17402.2|IPF27205.1|IPF18448.1|Contig4-2941_0010|orf6.4546|orf6.3021|CA1488|CA2591|orf19.60|IPF17402.5eoc|IPF17402 Protein involved in attachment of GPI-linked proteins to cell wall; member of major facilitator superfamily; phosphodiesterase/nucleotide pyrophosphatase domain; similar to S. cerevisiae Gpi7p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1064026 1064495 - ntar_101 1064026 1064495 1 1064495 1064026 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1064065 1065792 + orf19.4063 1064065 1065792 1 1064065 1065792 1064065 1065792 GPT1 orf19.11546|IPF19374.1|IPF10519.2|Contig4-2526_0008|orf6.248|orf6.249|orf6.3020|CA1487|CaO19.4063 GABA/polyamine transporter; 9 to 11 membrane spanning segments; complements GABA uptake defect of an S. cerevisiae uga4 put4 gap1 triple mutant; complements growth of an S. cerevisiae spe1 mutant under polyamine limitation [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr1 1064628 1064814 - ntar_102 1064628 1064814 1 1064814 1064628 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1065092 1065395 - ntar_103 1065092 1065395 1 1065395 1065092 1065395 1065213 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1066130 1067428 + orf19.4062 1066130 1067428 1 1066130 1067428 1066173 1067288 orf19.11544|IPF23189.1|IPF10521.2|Contig4-2526_0006|orf6.3019|CA1486|UAF21|CaO19.4062|CaO19.11544|IPF10521 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1067465 1068500 + orf19.4061 1067465 1068500 1 1067465 1068500 1067600 1068403 orf19.11543|IPF23191.1|IPF20082.1|Contig4-1646_0002|Contig4-2526_0004|orf6.3018|CA1485|CaO19.11543|CaO19.4061|IPF20082 Predicted ORF in Assemblies 19, 20 and 21; clade-associated gene expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1068391 1069805 - orf19.4060 1068391 1069805 1 1069805 1068391 1069691 1068579 ARO4 orf19.11542|IPF23190.1|IPF10524.2|Contig4-1646_0003|Contig4-2526_0003|orf6.3017|CA1484|CaO19.11542|CaO19.4060 3-Deoxy-D-arabinoheptulosonate-7-phosphate synthase; enzyme of aromatic amino acid biosynthesis; GCN-regulated; feedback-inhibited by tyrosine when produced in S. cerevisiae; fungal-specific; Aro3p and Aro4p catalyze the same reaction [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1070107 1072182 + orf19.4059 1070107 1072182 1 1070107 1072182 1070570 1071850 orf19.11541|IPF7656.2|IPF10526.2|Contig4-2526_0001|orf6.3016|orf6.785|CA1483|YHC3|CaO19.4059 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1072230 1072670 + orf19.4057 1072230 1072670 1 1072230 1072670 1072230 1072670 IPF7657.1|IPF28537.1|Contig4-1726_0002|Contig4-1812_0004|orf6.3014|orf6.784|CaO19.4057 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1082643 1083998 + orf19.4056 1082643 1083998 1 1082643 1083998 1082678 1083949 GAT2 orf19.11538|IPF23188.1|IPF7666.2|Contig4-2593_0012|orf6.2451|CA1120|CaO19.11538|CaO19.4056|IPF7666 Putative DNA-binding transcription factor; similar to S. cerevisiae Gat2p; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 1085006 1085239 - orf19.450 1085006 1085239 1 1085239 1085006 1085239 1085006 orf19.8080|IPF26889.1|IPF17483.2|Contig4-2593_0010|orf6.3089|CA1537|CaO19.8080|CaO19.450|IPF17483 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1088500 1088751 - ntar_104 1088500 1088751 1 1088751 1088500 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1092420 1094144 - orf19.449 1092420 1094144 1 1094144 1092420 1093862 1092666 orf19.8079|IPF17500.2|IPF5915.2|Contig4-2840_0016|orf6.1739|orf6.237|YKR70|CA0670|CaO19.449|IPF5915 Predicted ORF in Assemblies 19, 20 and 21; possible phosphatidyl synthase; transcription reduced upon yeast-hyphal switch; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1094621 1096060 - orf19.448 1094621 1096060 1 1096060 1094621 1096011 1094731 orf19.8078|IPF18257.2|IPF5918.2|Contig4-2840_0014|orf6.1738|orf6.6516|CA0669|CaO19.448|IPF5918 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1096326 1097020 + ntar_105 1096326 1097020 1 1096326 1097020 1096592 1096789 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1096874 1097700 - orf19.446.2 1096874 1097700 2 1097700|1097396 1097550|1096874 1097577 1097191 CA0668|IPF18910.3f Predicted ORF in Assembly 20 and 21; gene has intron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1097828 1099123 - orf19.446.1 1097828 1099123 2 1099123|1098498 1098601|1097828 1098637 1098305 CA6175|IPF5921 Predicted ORF in Assembly 20 and 21; gene has intron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1098793 1099230 + ntar_106 1098793 1099230 1 1098793 1099230 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1099190 1100243 - orf19.446 1099190 1100243 1 1100243 1099190 1100199 1099306 orf19.8076|IPF26878.1|IPF5922.2|Contig4-2840_0009|orf6.6515|CA4068|CaO19.446|CaO19.8076|IPF5922 Predicted ORF in Assemblies 19, 20 and 21; constitutive expression independent of MTL or white-opaque status; greater mRNA abundance observed in a cyr1 homozygous null mutant than in wild type; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1100579 1101071 + ntar_107 1100579 1101071 1 1100579 1101071 1100946 1101071 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1101103 1101252 + ntar_108 1101103 1101252 1 1101103 1101252 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1101132 1102511 - orf19.445 1101132 1102511 1 1102511 1101132 1102445 1101288 orf19.8075|IPF26872.1|IPF5924.2|Contig4-2840_0008|orf6.6514|CA4067|CaO19.445|CaO19.8075|IPF5924 Predicted ORF in Assemblies 19, 20 and 21; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1102531 1103144 - orf19.444 1102531 1103144 1 1103144 1102531 1103095 1102658 orf19.8074|IPF26891.1|IPF5925.2|Contig4-2840_0006|orf6.6513|CA4066|CaO19.8074|CaO19.444|IPF5925 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1103248 1104072 + orf19.443 1103248 1104072 1 1103248 1104072 1103345 1103932 orf19.8073|IPF26885.1|IPF5926.2|Contig4-2840_0004|orf6.6512|CA4065|CaO19.8073|RPC25|CaO19.443 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1103812 1105455 - orf19.441 1103812 1105455 1 1105455 1103812 1105392 1104058 RPT1 orf19.8071|IPF26869.1|IPF5928.2|Contig4-2840_0003|orf6.6510|CA4064|CaO19.8071|CaO19.441 Predicted ORF in Assemblies 19, 20 and 21; regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1104299 1104913 + orf19.442 1104299 1104913 1 1104299 1104913 1104299 1104913 IPF26884.1|IPF5927.1|orf6.6511 ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1105617 1107601 - orf19.440 1105617 1107601 1 1107601 1105617 1107598 1105682 SDH1 orf19.8070|IPF26863.1|IPF5931.2|Contig4-2840_0002|CA4063|CaO19.440|CaO19.8070|SDH11|orf6.6509 Protein described as mitochondrial succinate dehydrogenase; macrophage/pseudohyphal-induced; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1107960 1108970 - orf19.439 1107960 1108970 1 1108970 1107960 1108916 1108197 orf19.8069|IPF26880.1|IPF5933.2|orf6.6508|CA4062|CaO19.439|MHR1|CaO19.8069|IPF5933 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1108007 1108305 + ntar_109 1108007 1108305 1 1108007 1108305 1108042 1108305 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1109113 1111003 + orf19.438 1109113 1111003 1 1109113 1111003 1109186 1110934 orf19.8068|IPF26866.1|IPF5935.2|Contig4-2492_0006|orf6.6507|CA4061|CaO19.438|CaO19.8068|IPF5935 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1111151 1113339 + orf19.437 1111151 1113339 1 1111151 1113339 1111223 1113181 GRS1 orf19.8067|IPF26861.1|IPF5937.1|Contig4-2492_0003|orf6.6506|CA4060|CaO19.8067|CaO19.437 Putative tRNA-Gly synthetase; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1113160 1115503 - orf19.434 1113160 1115503 1 1115503 1113160 1115479 1113371 PRD1 orf19.8064|IPF5940.2|IPF29825.1|Contig4-2492_0001|Contig4-2492_0002|orf6.6503|CA4059|CaO19.8064|CaO19.434 Transcription is regulated by Nrg1p, Mig1p, and Tup1p; Hog1p-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1116103 1116195 + tp(ugg)1 1116103 1116195 2 1116103|1116160 1116138|1116195 tP(UGG)1.2 tRNA-Pro predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1116240 1118100 - orf19.433 1116240 1118100 1 1118100 1116240 1118038 1116296 orf19.8063|IPF7717.2|IPF29829.1|Contig4-2853_0014|orf6.6502|CA4058|CaO19.433|IPF7717 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1116288 1116632 + ntar_110 1116288 1116632 1 1116288 1116632 1116456 1116632 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1118214 1119699 - orf19.432 1118214 1119699 1 1119699 1118214 1119669 1118293 orf19.8062|IPF26870.1|IPF7719.2|Contig4-2853_0010|orf6.6501|CA4057|CaO19.8062|CaO19.432|IPF7719 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1118304 1118562 + ntar_111 1118304 1118562 1 1118304 1118562 1118407 1118562 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1118634 1119036 + ntar_112 1118634 1119036 1 1118634 1119036 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1119939 1122636 - orf19.431 1119939 1122636 1 1122636 1119939 1122299 1119972 ZCF2|orf19.8061|IPF26856.1|IPF7721.2|Contig4-2853_0009|orf6.6500|CA4056|CaO19.8061|CaO19.431|IPF7721 Putative transcription factor with zinc cluster DNA-binding motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1123131 1123950 + orf19.430 1123131 1123950 1 1123131 1123950 1123222 1123881 orf19.8060|IPF26882.1|IPF7723.2|Contig4-2853_0006|orf6.6499|CA4055|CaO19.430|YPT522|CaO19.8060 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1123724 1125796 - orf19.429 1123724 1125796 1 1125796 1123724 1125735 1123924 orf19.8059|IPF26865.1|IPF7724.2|Contig4-2853_0005|orf6.6498|CA4054|TRF4|CaO19.429|CaO19.8059 Predicted ORF in Assemblies 19, 20 and 21; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1125958 1128162 - orf19.428 1125958 1128162 1 1128162 1125958 1128162 1125979 orf19.8058|IPF26859.1|IPF7725.2|Contig4-2853_0002|Contig4-2853_0004|orf6.6497|CA4053|CaO19.428|CaO19.8058|IKS1 Predicted ORF in Assemblies 19, 20 and 21; induced during planktonic growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1126265 1126466 + ntar_113 1126265 1126466 1 1126265 1126466 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1128375 1133437 - orf19.427 1128375 1133437 1 1133437 1128375 1133437 1128440 orf19.8057|IPF10231.2|Contig4-2820_0001|Contig4-2820_0003|orf6.6496|CA4052|CaO19.8057|CaO19.427|IPF10231.3f|IPF10231.exon2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1133510 1135593 - orf19.426 1133510 1135593 1 1135593 1133510 1135564 1133510 orf19.8056|IPF26862.1|IPF10233.2|Contig4-2820_0006|orf6.6495|CA4051|CaO19.426|CaO19.8056|IPF10231.5f|IPF10231.exon1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1135789 1136407 - orf19.425 1135789 1136407 1 1136407 1135789 1136394 1135801 orf19.8055|IPF10482.exon2|IPF26883.1|IPF20007.1|Contig4-2820_0007|orf6.6494|CA4050|CaO19.8055|CaO19.425|IPF20007 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1136436 1137156 - orf19.424 1136436 1137156 1 1137156 1136436 1137135 1136581 TRP99 orf19.8054|orf6.6493|IPF10482.2|IPF19148.2|Contig4-2820_0008|orf6.770|CA4049|AHP12|CaO19.424|IPF10482|IPF10482.exon1 Protein described as thioredoxin peroxidase/alkyl hydroperoxide reductase; transcriptionally regulated by iron; expression greater in low iron; regulated by Gcn4p; induced in response to amino acid starvation (3-aminotriazole treatment) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1137212 1137964 + orf19.423 1137212 1137964 1 1137212 1137964 1137366 1137923 orf19.8053|IPF26887.1|IPF10483.2|Contig4-2820_0009|orf6.6492|orf6.771|CA0179|DCP1|CaO19.423 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1138223 1140710 + orf19.422 1138223 1140710 1 1138223 1140710 1138330 1140585 SPT20 orf19.8052|IPF18537.2|IPF10486.2|orf6.3893|orf6.6491|orf6.772|CA0180|CaO19.422 Protein described as a transcription factor; downregulated upon adherence to polystyrene; flucytosine repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1141047 1142880 - orf19.419 1141047 1142880 1 1142880 1141047 1142880 1141123 orf19.8049|IPF10490.2|IPF29828.1|Contig4-2233_0002|orf6.3896|CA2124|CaO19.419|IPF10490 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr1 1142135 1142629 + orf19.420 1142135 1142629 1 1142135 1142629 1142135 1142629 IPF26886.1|IPF10489.2|orf6.3895 [NOT TRANSCRIBED?] ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1143893 1148396 + orf19.418 1143893 1148396 1 1143893 1148396 1144029 1148327 KOG1 orf19.8048|IPF4893.2|orf6.3897|YHR186|CA2125|CaO19.418|CaO19.8048|IPF4893 Protein likely to be essential for growth, based on an insertional mutagenesis strategy; heterozygous null mutant displays sensitivity to rapamycin [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1148988 1150350 + orf19.417 1148988 1150350 1 1148988 1150350 1149163 1150212 orf19.8047|IPF26873.1|IPF4896.2|Contig4-3004_0025|orf6.3898|CA2126|CaO19.8047|MTM1|CaO19.417|IPF4896 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1150320 1151467 - orf19.416 1150320 1151467 1 1151467 1150320 1151467 1150346 orf19.8046|IPF26874.1|IPF4897.2|Contig4-3004_0024|orf6.3899|CA2127|CaO19.416|CaO19.8046|IPF4897 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr1 1151619 1152563 - orf19.415 1151619 1152563 1 1152563 1151619 1152503 1151757 orf19.8045|IPF26879.1|IPF4898.1|Contig4-3004_0021|orf6.3900|CA2128|CaO19.415|CaO19.8045|IPF4898 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1152799 1155235 + orf19.414 1152799 1155235 1 1152799 1155235 1152818 1155091 orf19.8044|IPF26851.1|IPF4899.1|Contig4-3004_0020|orf6.3901|CA2129|CaO19.8044|RSM22|CaO19.414|IPF4899 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1155065 1155981 - orf19.413.1 1155065 1155981 1 1155981 1155065 1155839 1155591 RPS27A IPF4901.2|IPF29837.1|Contig4-3004_0018|CA2130 Predicted ribosomal protein S27; ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1157565 1158002 + ntar_114 1157565 1158002 1 1157565 1158002 1157725 1157907 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1158458 1158691 - ntar_115 1158458 1158691 1 1158691 1158458 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1158687 1161263 + orf19.413 1158687 1161263 1 1158687 1161263 1158929 1161004 orf19.8043|orf6.2094|IPF4902.1|IPF29827.1|Contig4-3004_0013|CA0897|CaO19.413|IPF4902 Transcription is positively regulated by Sfu1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1161098 1163002 - orf19.412 1161098 1163002 2 1163002|1162819 1162930|1161098 1162939 1161330 orf19.8042|IPF4903.2|Contig4-3004_0010|orf6.2095|CA0898|SSH1.3f|SSH1.3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1163383 1164837 - orf19.411 1163383 1164837 1 1164837 1163383 1164670 1163651 orf19.8041|IPF4905|orf6.2096|IPF26877.1|IPF4905.2|Contig4-3004_0007|CA0899|CaO19.8041|CaO19.411 Protein described as similar to GTPase regulators; possibly spurious ORF (Annotation Working Group prediction); transcriptionally regulated by iron; expression greater in low iron; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1163572 1163775 + ntar_116 1163572 1163775 1 1163572 1163775 1163628 1163768 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1165074 1165380 + ntar_117 1165074 1165380 1 1165074 1165380 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1165950 1166791 - ntar_1426 1165950 1166791 2 1166791|1166462 1166716|1165950 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1166924 1167711 + orf19.410.3 1166924 1167711 2 1166924|1167176 1167092|1167711 1166924 1167627 IPF26888.1|IPF4908.2|Contig4-3004_0003|CA0054|RIB4|RIB4.3 Lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase); catalyzes the penultimate step in the synthesis of riboflavin [label_first_exon=CGD label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1168044 1168149 + tn(guu)2 1168044 1168149 2 1168044|1168114 1168081|1168149 tN(GUU)2.2 tRNA-Asn predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1168236 1168338 + tn(guu)1 1168236 1168338 2 1168236|1168303 1168273|1168338 tN(GUU)1.2 tRNA-Asn predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1168890 1168962 + tt(agu)1 1168890 1168962 1 1168890 1168962 tT(AGU)1.2 tRNA-Thr predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1169086 1170573 - ntar_118 1169086 1170573 1 1170573 1169086 1170573 1170313 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1169252 1173967 + orf19.2495 1169252 1173967 1 1169252 1173967 1169252 1173967 GSL1 orf19.10031|FKS1|IPF24875.1|IPF4913.2|GSL22|Contig4-2966_0001|Contig4-2966_0003|orf6.6176|CA3812|CaO19.2495|CaO19.10031 Subunit of beta-1,3-glucan synthase; 10 predicted membrane-spanning regions; caspofungin induced; mRNA abundance declines after yeast-to-hyphal transition; similar to S. cerevisiae Fks3p; fungal-specific (no human or murine homolog) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr1 1174270 1177116 + orf19.2494 1174270 1177116 1 1174270 1177116 1174271 1175737 orf19.10030|IPF24837.1|IPF9233.1|Contig4-2966_0004|orf6.6175|CA3811|CaO19.2494|PET112|CaO19.10030 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1175824 1177077 - orf19.2492 1175824 1177077 1 1177077 1175824 1177077 1175824 STE3 orf19.10028|IPF24844.1|IPF9230.2|Contig4-2966_0005|orf6.6173|CA3810|CaO19.10028|CaO19.2492|IPF9230 Protein similar to S. cerevisiae Ste3p, the receptor for a-factor mating pheromone; alpha mating-type-specific transcription [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1177497 1181017 - orf19.2489 1177497 1181017 1 1181017 1177497 1180920 1177591 orf19.10025|IPF24889.1|IPF9227.2|Contig4-2966_0006|orf6.6170|CA3809|CaO19.2489|KAP123|CaO19.10025 Predicted ORF in Assemblies 19, 20 and 21; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1181039 1182441 - orf19.2488 1181039 1182441 1 1182441 1181039 1182403 1181204 FAL1 orf19.10024|IPF24847.1|IPF9226.2|Contig4-2966_0007|orf6.6169|CA3808|CaO19.10024|CaO19.2488 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1182511 1183402 + orf19.2487 1182511 1183402 1 1182511 1183402 1182555 1183313 orf19.10023|IPF24863.1|IPF9225.2|Contig4-2966_0009|orf6.6168|CA3807|CaO19.2487|CaO19.10023|IPF9225 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1183302 1187736 - orf19.2485 1183302 1187736 1 1187736 1183302 1187646 1183366 orf19.10021|IPF24880.1|IPF9224.2|Contig4-2966_0010|Contig4-2966_0011|orf6.6166|CA3806|CaO19.2485|NUP170|CaO19.10021|IPF9224 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1188173 1189603 + orf19.2484 1188173 1189603 1 1188173 1189603 1188231 1189484 orf19.10020|IPF24843.1|IPF12403.2|Contig4-2966_0014|orf6.6165|CA3805|CaO19.2484|CaO19.10020|IPF12403 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1189424 1190085 - orf19.2483 1189424 1190085 1 1190085 1189424 1190013 1189582 RIM1 orf19.10019|IPF24873.1|IPF12405.2|Contig4-2966_0015|orf6.6164|CA3804|CaO19.10019|CaO19.2483 Predicted ORF in Assemblies 19, 20 and 21; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1190292 1191038 - orf19.2481 1190292 1191038 1 1191038 1190292 1191038 1190292 orf19.10017|IPF24864.1|IPF12407.1|Contig4-2966_0017|orf6.6162|CA3803|CaO19.10017|CaO19.2481|IPF12407 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1191283 1192452 + orf19.2480.1 1191283 1192452 3 1191283|1191617|1191749 1191442|1191664|1192452 1191631 1192122 AUT7 IPF12408.2|IPF7188.3|Contig4-2966_0018|orf6.109|CA3802|AUT7.exon2 ORF Predicted by Annotation Working Group; macrophage/pseudohyphal-repressed; intron in 5'-UTR [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1192486 1194234 - orf19.2479 1192486 1194234 1 1194234 1192486 1194234 1192561 UGA4 orf19.10016|IPF7194.1|IPF12411.3|Contig4-2471_0004|orf6.107|orf6.6161|CA3801|UGA40|CaO19.2479 Putative gamma-aminobutyric acid/polyamine permease; nitrogen catabolite repressed gene, induced in absence of preferred N sources; transcriptionally induced upon phagocytosis by macrophage; gene regulation by nitrogen source requires Gat1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr1 1195183 1197114 + orf19.2478.1 1195183 1197114 3 1195183|1195817|1196132 1195228|1195907|1197114 1195221 1196758 IPF7197.2|IPF16942.2|Contig4-2471_0002|orf6.4956|CA3800|RPL7A.3f|RPL7A.3 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1196975 1198230 - orf19.2478 1196975 1198230 1 1198230 1196975 1198188 1197046 orf19.10015|IPF7198.1|IPF16941.2|Contig4-2471_0001|orf6.4957|orf6.6160|CA3799|CaO19.2478|IPF7198 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1198336 1203538 - orf19.2476 1198336 1203538 1 1203538 1198336 1203457 1198403 orf19.10013|IPF24871.1|IPF7201.2|Contig4-2471_0005|orf6.4959|orf6.6159|CA2884|CaO19.2476|IPF7201 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1203590 1203921 + ntar_119 1203590 1203921 1 1203590 1203921 1203590 1203859 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1203688 1204754 - orf19.2475 1203688 1204754 1 1204754 1203688 1204573 1204178 PGA26 orf19.10012|orf6.4960|IPF24884.1|IPF7204.2|Contig4-2954_0019|CA2885|CaO19.10012|CaO19.2475|IPF7204 Putative GPI-anchored protein of unknown function; transcriptionally regulated by iron; expression greater in high iron; induced during cell wall regeneration; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1205343 1205560 + ntar_120 1205343 1205560 1 1205343 1205560 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1205966 1207881 - orf19.2474 1205966 1207881 1 1207881 1205966 1207750 1206098 PRC3 orf19.10011|IPF7205.2|IPF29082.1|Contig4-2954_0018|orf6.230|orf6.4961|CA0035|CPY2|CaO19.2474 Transcription is regulated by Nrg1p and Mig1p; regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1208447 1210541 + orf19.2473 1208447 1210541 1 1208447 1210541 1208547 1210451 orf19.10010|IPF24831.1|IPF7207.2|IPF7207|Contig4-2954_0014|orf6.4962|CA2886|CaO19.2473|CaO19.10010 Decreased transcription is observed upon fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1210663 1211092 + orf19.2472.1 1210663 1211092 1 1210663 1211092 1210733 1210942 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1210934 1211792 - orf19.2472 1210934 1211792 1 1211792 1210934 1211754 1211062 orf19.10009|IPF24865.1|IPF13631.1|Contig4-2954_0012|orf6.4963|CA2887|CaO19.2472|CaO19.10009|IPF13631 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1211870 1212493 + orf19.2471 1211870 1212493 1 1211870 1212493 1211899 1212375 GIM5 orf19.10008|IPF24870.1|IPF13630.1|Contig4-2954_0011|orf6.4964|CA2888|CaO19.2471|CaO19.10008 Predicted ORF in Assemblies 19, 20 and 21; macrophage/pseudohyphal-repressed gene and macrophage-induced protein [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1212358 1213445 - orf19.2469 1212358 1213445 1 1213445 1212358 1213425 1212409 RAD10 orf19.10006|IPF24857.1|IPF13628.1|Contig4-2954_0010|orf6.4966|CA2889|CaO19.2469|ERC1|CaO19.10006|IPF13628 Ortholog of S. cerevisiae RAD10, an endonuclease involved in nucleotide excision repair; null mutant is extremely sensitive to UV irradiation; transcription is downregulated in alkaline conditions [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1213982 1214902 + orf19.2468 1213982 1214902 1 1213982 1214902 1213982 1214902 orf19.10005|IPF6685.3|IPF13626.2|Contig4-2954_0008|orf6.250|orf6.4967|CA2890|TMT1|CaO19.2468|IPF13626 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1215228 1216520 + orf19.2467 1215228 1216520 1 1215228 1216520 1215353 1216498 PRN1 orf19.10004|IPF13624.2|IPF6686.2|Contig4-2954_0007|orf6.251|orf6.4968|CA2891|IFS4|PIRIN-1|CaO19.2467 Protein with similarity to pirins; increased transcription is observed upon benomyl treatment and in response to alpha pheromone in SpiderM medium; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1216778 1218096 + orf19.2465 1216778 1218096 1 1216778 1218096 1216800 1218017 POL32 orf19.10002|IPF24845.1|IPF6688.2|Contig4-2954_0004|orf6.4970|CA2892|CaO19.2465|CaO19.10002|IPF6688 Predicted ORF in Assemblies 19, 20 and 21; cell-cycle regulated periodic mRNA expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1218205 1219372 + orf19.2463 1218205 1219372 1 1218205 1219372 1218316 1219317 PRN2 orf19.10000|IPF24858.1|IPF6690.2|Contig4-2954_0003|orf6.4972|CA2893|CaO19.10000|CaO19.2463|IFS3 Predicted ORF in Assemblies 19, 20 and 21; similar to pirin [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1219643 1220882 + orf19.2462 1219643 1220882 1 1219643 1220882 1219834 1220814 PRN3 orf19.9999|IPF24854.1|IPF6691.1|Contig4-2954_0001|orf6.4973|CA2894|CaO19.2462|IFS2 Predicted ORF in Assemblies 19, 20 and 21; similar to pirin; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1221320 1222663 + orf19.2461 1221320 1222663 1 1221320 1222663 1221590 1222576 PRN4 orf19.9998|IPF24852.1|IPF6694.2|Contig4-2709_0011|orf6.4974|CA2895|IFS1|CaO19.2461|CaO19.9998 Protein with similarity to pirins; increased transcription is observed upon benomyl treatment [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1223688 1225228 + orf19.2460 1223688 1225228 1 1223688 1225228 1223738 1224793 orf19.9997|IPF6696.2|IPF18403.2|Contig4-2709_0008|orf6.3562|orf6.4975|CA1873|CaO19.2460|IPF6696 Predicted ORF in Assemblies 19, 20 and 21; exogenously expressed protein is a substrate for Kex2p processing in vitro; transcription is repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1226421 1229872 + orf19.2459 1226421 1229872 1 1226421 1229872 1226736 1229654 orf19.9996|IPF24817.1|IPF6700.2|Contig4-2709_0005|orf6.3561|CA1872|CaO19.2459|CaO19.9996|IPF6700 Putative protein of unknown function; mRNA binds to She3p; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1231114 1233040 + orf19.2458 1231114 1233040 1 1231114 1233040 1231428 1232969 orf19.9995|IPF18595.1|IPF6704.2|Contig4-2709_0001|orf6.266|orf6.3559|orf6.3560|CA1871|SIP5|CaO19.2458|IPF16981|CA1870|IPF16981.exon2|IPF16981.2|IPF16981.exon1 Putative transcription factor with zinc finger DNA-binding motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1236231 1238527 + orf19.2457 1236231 1238527 1 1236231 1238527 1236354 1238429 orf19.9993|IPF15822.2|IPF19473.2|orf6.34|orf6.3558|CA1869|CaO19.2457|IPF15822 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 1238405 1242092 - orf19.2455 1238405 1242092 1 1242092 1238405 1241973 1238578 orf19.9992|IPF18597.2|IPF24840.1|IPF29084.1|IPF14501.3|Contig4-2518_0001|orf6.1539|orf6.33|orf6.3557|orf6.373|CA0547|CA1868|orf19.2456|IPF14501.5f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1242794 1243551 - ntar_121 1242794 1243551 1 1243551 1242794 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1243990 1244422 + ntar_122 1243990 1244422 1 1243990 1244422 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1244534 1247879 + orf19.2454 1244534 1247879 1 1244534 1247879 1244696 1247716 PHO87 orf19.9990|orf6.1540|PHO98|IPF19824.2|IPF14853.2|Contig4-2200_0003|Contig4-2200_0004|Contig4-2200_0005|orf6.104|orf6.293|CA0548|CaO19.2454|CA0015|PHO87.5eoc|IPF19824.1 Protein similar to phosphate permeases; transcription is negatively regulated by Rim101p at pH 8; expression is regulated upon white-opaque switching; caspofungin repressed; biofilm-regulated; virulence-group-correlated expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1248065 1249905 - orf19.2452 1248065 1249905 1 1249905 1248065 1249509 1248262 orf19.9988|orf6.1246|IPF14850.2|IPF14849.3|Contig4-2200_0007|Contig4-2200_0010|orf6.294|CA0046|CaO19.2452|IPF14850 Transcriptionally regulated by iron; expression greater in high iron; downregulated in core caspofungin response; ketoconazole-repressed; shows colony morphology-related gene regulation by Ssn6p; possibly subject to Kex2p processing [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1251400 1253230 + orf19.2451 1251400 1253230 1 1251400 1253230 1251599 1252987 PGA45 orf19.9987|IPF19428.2|IPF14109.2|Contig4-1947_0002|orf6.1247|orf6.143|CA0380|CaO19.2451|IPF14109 Cell wall protein; putative GPI-anchor; downregulated in core caspofungin response; Hog1p-induced; regulated by Ssn6p; Mob2p-dependent hyphal regulation; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1254890 1256662 + orf19.2449 1254890 1256662 1 1254890 1256662 1254890 1256662 orf19.9985|IPF14107.2|IPF7471.3|Contig4-2783_0009|orf6.1249|CA0788|CaO19.2449|IPF14107|orf6.1922 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21; macrophage-induced gene [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1257029 1259362 + orf19.2447 1257029 1259362 1 1257029 1259362 1257154 1259244 orf19.9983|IPF24830.1|IPF7472.1|Contig4-2783_0008|orf6.1920|CA0787|CaO19.2447|CaO19.9983|IPF7472 Predicted ORF in Assemblies 19, 20 and 21; decreased expression observed in an ssr1 homozygous null mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1259137 1260575 - orf19.2446 1259137 1260575 1 1260575 1259137 1260405 1259335 orf19.9982|IPF24855.1|IPF7473.1|Contig4-2783_0007|orf6.1919|CA0786|CaO19.9982|CaO19.2446|IPF7473 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1261730 1263376 + orf19.2445 1261730 1263376 1 1261730 1263376 1261730 1263376 orf19.9981|IPF24835.1|IPF7474.3|DIP51|Contig4-2783_0004|orf6.1918|orf6.3623|DIP5|CA1922|DIP52|CaO19.2445|IPF7474.2 [NOT TRANSCRIBED?] Putative dicarboxylic amino acid permease; fungal-specific (no human or murine homolog); transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1263826 1264960 + orf19.2444 1263826 1264960 1 1263826 1264960 1263887 1264819 CHS7 orf19.9980|IPF24859.1|IPF7475.2|Contig4-2783_0003|orf6.3622|CA1921|CaO19.9980|CaO19.2444|IPF7475 Protein required for wild-type chitin synthase III activity; similar to (but not functional homolog of) S. cerevisiae Chs7p, which effects ER export of Chs3p; induced in homozygous cyr1 null mutant hyphae and ras1 yeast-form cells [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1265312 1267673 + orf19.2443 1265312 1267673 1 1265312 1267673 1265549 1267582 RGD1 orf19.9979|orf6.3621|IPF24828.1|IPF7476.2|Contig4-2783_0001|CA1920|CaO19.2443|CaO19.9979|IPF7476 Protein described as a GTPase activator; transcriptionally regulated by iron; expression greater in low iron; alkaline upregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1267600 1268514 - orf19.2442 1267600 1268514 1 1268514 1267600 1268401 1267601 orf19.9978|IPF24861.1|IPF7477.2|IPF7477|orf6.3620|CA1919|CaO19.9978|CaO19.2442 Decreased transcription is observed in an azole-resistant strain that overexpresses MDR1 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1268576 1271291 + orf19.2440 1268576 1271291 1 1268576 1271291 1268667 1271219 orf19.9976|orf19.9977|IPF24850.1|IPF24836.1|IPF7479.2|IPF7478.2|orf6.3618|orf6.3619|CA1917|CA1918|orf19.2441|IPF7479.3f Predicted ORF in Assemblies 19, 20 and 21; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 1271173 1271745 - orf19.2439.1 1271173 1271745 2 1271745|1271579 1271685|1271173 1271693 1271352 IPF24823.1|IPF16566.2|CA1916|IPF16566.3 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1271967 1272685 - orf19.2439 1271967 1272685 1 1272685 1271967 1272642 1272208 orf19.9975|IPF24877.1|IPF16565.1|Contig4-2388_0002|orf6.3617|CA1915|CaO19.2439|ACP12|CaO19.9975|IPF16565 Predicted ORF in Assemblies 19, 20 and 21; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1272835 1273510 + orf19.2438 1272835 1273510 1 1272835 1273510 1272885 1273427 orf19.9974|IPF24866.1|IPF16564.1|Contig4-2388_0004|orf6.3616|CA1914|CaO19.9974|MRPS12|CaO19.2438|IPF16564 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1273410 1274594 - orf19.2437 1273410 1274594 1 1274594 1273410 1274555 1273515 ARC35 orf19.9973|IPF24856.1|IPF16563.2|Contig4-2388_0006|orf6.3615|CA1913|CaO19.2437|CaO19.9973 Predicted ORF in Assemblies 19, 20 and 21; shows colony morphology-related gene regulation by Ssn6p; mutation confers hypersensitivity to cytochalasin D [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1274799 1277841 - orf19.2436 1274799 1277841 1 1277841 1274799 1277567 1274919 orf19.9972|IPF24821.1|IPF13772.2|Contig4-2388_0008|orf6.3614|CA1912|SKY1|CaO19.9972|CaO19.2436 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1278550 1280804 - orf19.2435 1278550 1280804 1 1280804 1278550 1280738 1278633 MSI3 orf19.9971|orf6.760|SSE1|IPF24829.1|IPF13776.3|orf6.3613|CA1911|CaO19.2435|IPF13776.2 Protein of the HSP70 family; antigenic; functional homolog of S. cerevisiae Msi3p; physically interacts (by 2-hybrid) with Cgr1p; transcriptionally regulated by iron; expression greater in high iron; farnesol downregulated in biofilm [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1281093 1283039 - orf19.2434 1281093 1283039 1 1283039 1281093 1282994 1281198 NPL4 orf19.9970|IPF19684.1|IPF15600.2|Contig4-2898_0001|orf6.1397|orf6.761|CA0175|CaO19.2434 Predicted ORF in Assemblies 19, 20 and 21; regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1283124 1283839 - orf19.2433 1283124 1283839 1 1283839 1283124 1283769 1283140 orf19.9969|IPF17719.1|IPF15601.1|Contig4-2898_0002|orf6.1396|orf6.762|CA0458|CaO19.2433|IPF15601 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1284338 1285921 - orf19.2432 1284338 1285921 2 1285921|1284420 1284440|1284338 1285460 1284338 HAC1 orf19.9968|IPF24851.1|IPF15604.1|Contig4-2898_0003|orf6.1395|CA0457|CaO19.2432|CaO19.9968|IPF15604 Putative transcription factor involved in unfolded protein response and control of morphology; transcript undergoes atypical splicing at C terminus under ER stress; induced during mating and by caspofungin; mRNA binds She3p [label_first_exon=CGDmod label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1286014 1286424 - orf19.2431 1286014 1286424 1 1286424 1286014 1286424 1286083 orf19.9967|IPF24888.1|IPF29100.1|orf6.1394|CaO19.2431|CaO19.9967 Dubious open reading frame, not conserved in Candida species; transcription is induced in response to alpha pheromone in SpiderM medium; mRNA binds She3p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 1286804 1287167 + ntar_123 1286804 1287167 1 1286804 1287167 1287018 1287167 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1288962 1289687 + orf19.2430 1288962 1289687 1 1288962 1289687 1288962 1289687 orf19.9966|IPF19414.2|IPF16122.1|Contig4-2898_0010|orf6.1393|orf6.169|LPF19|CaO19.2430 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1289718 1291073 + orf19.2429 1289718 1291073 1 1289718 1291073 1289718 1291073 orf19.9965|IPF24841.1|IPF19572.1|IPF19573.1|Contig4-2898_0011|orf6.333|orf6.1392|CA0053|orf19.380|CaO19.9965|LPF18|CaO19.2429 Predicted ORF in Assemblies 19, 20 and 21; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1291710 1292041 - ntar_124 1291710 1292041 1 1292041 1291710 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1292869 1293864 + orf19.2661 1292869 1293864 1 1292869 1293864 1292869 1293864 TLO34 IPF11534.1|IPF17380.2|Contig4-1945_0002|Contig4-2584_0004|Contig4-2753_0010|Contig4-2898_0012|Contig4-2956_0007|orf6.334|orf6.434|orf6.1466|CA0498|CA0078|orf19.631|orf19.381|CaO19.2661|CTA218|CTA211.3f Non-telomeric member of a family of telomere-proximal genes of unknown function; predicted N-terminus is extended, relative to that of other family members [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr1 1293072 1293677 - orf19.2662 1293072 1293677 1 1293677 1293072 1293677 1293072 IPF11536.1|orf6.1467|CaO19.2662|ATC218 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1294318 1297038 + orf19.2663 1294318 1297038 1 1294318 1297038 1294913 1296667 orf19.9388|IPF25503.1|IPF14507.3|IPF11533.1|Contig4-2753_0011|orf6.3436|orf6.1468|CA0499|orf19.1829|LPF20|CaO19.2663|IFA9 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1296767 1297043 - ntar_125 1296767 1297043 1 1297043 1296767 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1297193 1298596 + orf19.1828 1297193 1298596 1 1297193 1298596 1297270 1298319 BUD16 orf19.9387|IPF25500.1|IPF14508.2|Contig4-2753_0012|orf6.3435|CA1781|CaO19.1828|CaO19.9387|IPF14508 Protein similar to S. cerevisiae Bud16p; induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1298462 1299820 - orf19.1827 1298462 1299820 1 1299820 1298462 1299820 1298462 orf19.9386|IPF25499.1|IPF14509.2|Contig4-2753_0014|orf6.3434|CA1780|CaO19.9386|CaO19.1827|IPF14509 Predicted ORF in Assemblies 19, 20 and 21; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1300582 1302956 - orf19.1826 1300582 1302956 1 1302956 1300582 1302625 1300757 MDM34 orf19.9385|IPF25496.1|IPF14510.2|Contig4-2618_0001|Contig4-2753_0016|orf6.3433|CA1779|CaO19.1826|CaO19.9385|IPF14510 Putative transcription factor with zinc finger DNA-binding motif; macrophage-downregulated gene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1306306 1308657 + orf19.1825 1306306 1308657 1 1306306 1308657 1306306 1308531 orf19.9384|IPF13810|IPF25495.1|IPF13810.2|Contig4-2618_0004|orf6.1511|orf6.3432|CA1778|CaO19.9384|CaO19.1825|IPF13810.3 [NOT TRANSCRIBED?] Protein not essential for viability; filament induced; regulated by Nrg1p, Rfg1p, Tup1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 1309559 1310488 + orf19.1824 1309559 1310488 1 1309559 1310488 1309559 1310488 PGA50 orf19.9383|IPF25501.1|IPF14706.2|Contig4-2618_0008|orf6.3431|CA1777|CaO19.9383|CaO19.1824|IPF14706 Putative GPI-anchored protein of unknown function [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1310758 1313731 + orf19.1823 1310758 1313731 1 1310758 1313731 1310872 1313613 orf19.9382|IPF14704|IPF25493.1|IPF14704.2|Contig4-2618_0011|Contig4-2618_0014|orf6.1325|orf6.3430|CA1776|CaO19.1823 Predicted ORF in Assemblies 19, 20 and 21; transcription is downregulated in response to treatment with ciclopirox olamine [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1313907 1314266 + ntar_126 1313907 1314266 1 1313907 1314266 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1314494 1317025 - orf19.1822 1314494 1317025 1 1317025 1314494 1317025 1314494 UME6 orf19.9381|IPF15273.2|IPF14703.2|Contig4-1197_0003|orf6.1326|orf6.3429|CA0423|CaO19.1822|IPF15273 Transcription factor; required for wild-type hyphal extension, virulence; zinc cluster DNA-binding motif; similar to S. cerevisiae Ume6p, which is a meiotic regulator; alkaline upregulated; filament induced; regulated by Nrg1p, Tup1p, RFG1p [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1324514 1324825 - orf19.1821 1324514 1324825 1 1324825 1324514 1324825 1324514 orf19.9380|IPF25509.1|IPF29296.1|orf6.1209|CaO19.9380|CaO19.1821 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21; transcription is repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1334471 1334753 + ntar_127 1334471 1334753 1 1334471 1334753 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1337508 1340227 + orf19.177 1337508 1340227 1 1337508 1340227 1337672 1340068 orf19.13660|orf19.7810|IPF27140.1|IPF15923.2|IPF20924.1|IPF11945.2|orf6.679|orf6.6040|CA0151|CA3703|orf19.6281|IPF15923.5eoc Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 1340369 1340722 + orf19.6280 1340369 1340722 1 1340369 1340722 1340369 1340722 orf19.13659|IPF20954.1|IPF27787.1|orf6.6039|CaO19.13659|CaO19.6280 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1343993 1344599 + ntar_128 1343993 1344599 1 1343993 1344599 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1344770 1348341 + orf19.6277 1344770 1348341 1 1344770 1348341 1344908 1348267 orf19.13656|orf19.13658|IPF19586.1|IPF19587.2|orf6.501|orf6.6038|CA3701|CA3702|orf19.6279|IPF11936.3f|orf6.6036 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 1350390 1350606 + ntar_129 1350390 1350606 1 1350390 1350606 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1350853 1353640 + orf19.6276 1350853 1353640 1 1350853 1353640 1350853 1353474 orf19.13655|IPF20884.1|IPF4859.2|Contig4-2377_0008|orf6.6035|CA3700|CaO19.6276|CaO19.13655|IPF4859 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr1 1354052 1355749 + orf19.6275 1354052 1355749 1 1354052 1355749 1354052 1355749 orf19.13654|IPF20904.1|IPF4860.1|Contig4-2377_0002|Contig4-2377_0004|orf6.6034|CA3699|CaO19.13654|CaO19.6275|IPF4860 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr1 1356578 1357373 - orf19.6274 1356578 1357373 1 1357373 1356578 1357330 1356803 PBR1 orf19.13653|IPF20933.1|IPF4861.1|Contig4-2683_0016|orf6.6033|CA3698|CaO19.6274|CaO19.13653|IPF4861 Protein required for cohesion, adhesion, and biofilm formation; induced by alpha pheromone in white cells [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1358770 1359775 - orf19.6273 1358770 1359775 1 1359775 1358770 1359770 1359447 orf19.13652|IPF4865.1|IPF27790.1|Contig4-2683_0013|orf6.6032|CaO19.13652|CaO19.6273 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1359971 1361046 + orf19.6272 1359971 1361046 1 1359971 1361046 1360018 1360794 orf19.13651|IPF4866.1|IPF27771.1|Contig4-2683_0012|orf6.6031|CA3697|YUH1|CaO19.6272|IPF4866 Predicted ORF in Assemblies 19, 20 and 21; regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1360739 1363376 - orf19.6271 1360739 1363376 1 1363376 1360739 1363202 1361070 orf19.13650|IPF4868.1|IPF27760.1|Contig4-2683_0009|orf6.6030|CA3696|CaO19.6271|IPF4868 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1364433 1367174 + orf19.6269 1364433 1367174 1 1364433 1367174 1364477 1367062 orf19.13648|orf19.13649|IPF20912.1|IPF4873.2|Contig4-2683_0004|Contig4-2683_0006|orf6.6028|orf6.6029|CA3694|CA3695|orf19.6270|IPF4872.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 1367091 1369525 - orf19.6268 1367091 1369525 1 1369525 1367091 1369348 1367174 orf19.13647|IPF20895.1|IPF4874.2|Contig4-2683_0002|orf6.6027|CA3693|CaO19.13647|CaO19.6268|IPF4874 Predicted ORF in Assemblies 19, 20 and 21; decreased expression observed in an ssr1 homozygous null mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1370850 1372217 - orf19.6267 1370850 1372217 1 1372217 1370850 1372217 1370850 orf19.13646|IPF4876|IPF20913.1|IPF4876.2|Contig4-2747_0018|orf6.6026|CA3692|CaO19.13646|HRQ3|CaO19.6267 Protein not essential for viability [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1372774 1375485 - orf19.6266 1372774 1375485 1 1375485 1372774 1375483 1372868 orf19.13645|IPF20885.1|IPF4880.2|Contig4-2747_0014|Contig4-2747_0015|Contig4-2747_0016|orf6.6025|CA3691|CaO19.6266|CaO19.13645|IPF4880 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1375744 1376785 - orf19.6265.1 1375744 1376785 2 1376785|1376301 1376732|1375744 1376741 1375913 RPS14B IPF20952.1|IPF4881.1|Contig4-2747_0012|CA3690|RPS14 Putative ribosomal protein; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage; transcription is positively regulated by Tbf1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1377035 1377529 - orf19.6265 1377035 1377529 1 1377529 1377035 1377498 1377106 RPS22A orf19.13644|IPF20939.1|IPF4882.2|Contig4-2747_0010|orf6.6024|CA3689|RPS22|CaO19.6265|CaO19.13644 Predicted ribosomal protein; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1377722 1378625 + orf19.6264.4 1377722 1378625 2 1377722|1378119 1377887|1378625 1377882 1378268 IPF20908.1|IPF27767.1 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1378483 1379422 - orf19.6264.3 1378483 1379422 2 1379422|1379188 1379270|1378483 1379293 1378685 IPF20936.1|IPF4885.1|Contig4-2747_0006|orf6.6072|CA3688|YIP3|YIP3.3 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1379833 1380253 - ntar_130 1379833 1380253 1 1380253 1379833 1380144 1379923 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1380365 1381401 + orf19.6264 1380365 1381401 1 1380365 1381401 1380462 1381178 orf19.13643|IPF20926.1|IPF4889.2|Contig4-2747_0003|orf6.6023|CA3687|CaO19.13643|CaO19.6264|IPF4889 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1381182 1382664 - orf19.6263 1381182 1382664 1 1382664 1381182 1382602 1381205 orf19.13642|IPF4890.2|IPF18757.2|Contig4-2747_0002|orf6.6022|CA3686|CaO19.13642|CaO19.6263|IPF4890 Predicted membrane transporter, member of the monocarboxylate porter (MCP) family, major facilitator superfamily (MFS) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1382841 1389718 - orf19.6261 1382841 1389718 1 1389718 1382841 1389718 1382897 BPH1 orf19.13640|IPF20927.1|IPF19723.1|Contig4-2747_0021|orf6.111|orf6.2456|orf6.301|CA1123|CaO19.6261|IPF19723 Protein not essential for viability; similar to S. cerevisiae Bph1p, which is a putative ortholog of human Chediak-Higashi syndrome protein and murine beige gene implicated in disease syndromes involving defective lysosomal trafficking [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr1 1390173 1394538 - orf19.6260 1390173 1394538 1 1394538 1390173 1394401 1390283 orf19.13639|IPF19349.2|IPF12859.2|Contig4-2735_0006|orf6.2457|CA1124|UBP12|CaO19.6260 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1394979 1396220 - orf19.6259 1394979 1396220 1 1396220 1394979 1396220 1395099 orf19.13638|IPF12718.3|IPF12854.2|Contig4-2735_0003|orf6.2458|orf6.654|CA1125|CaO19.6259|RRP43 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 1397888 1404671 + orf19.6257 1397888 1404671 1 1397888 1404671 1398250 1404630 GLT1 orf19.13636|IPF20929.1|IPF19715.2|orf6.2272|orf6.655|CA1010|CaO19.6257|GLT1.3eoc|IPF19715.1 Putative glutamate synthase; alkaline downregulated; transcription is downregulated in both intermediate and mature biofilms [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1404849 1406663 + orf19.6255 1404849 1406663 1 1404849 1406663 1404890 1406203 orf19.13634|IPF20914.1|IPF14084.1|Contig4-2748_0008|orf6.2270|CA1009|CaO19.13634|CaO19.6255|IPF14084 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1406978 1408563 + orf19.6254 1406978 1408563 1 1406978 1408563 1407331 1408368 ANT1 orf19.13633|IPF20920.1|IPF14083.2|Contig4-2748_0006|orf6.2269|CA1008|CaO19.6254|CaO19.13633|IPF14083 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1409014 1409688 + orf19.6253 1409014 1409688 1 1409014 1409688 1409046 1409483 RPS23A orf19.13632|IPF13519.1|IPF14082.3|Contig4-2748_0005|orf6.1570|orf6.2268|CA0567|CaO19.6253|RPS23|RPS23.5f Putative ribosomal protein; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1409669 1411539 - orf19.6252 1409669 1411539 1 1411539 1409669 1411044 1409842 orf19.13630|IPF20915.1|IPF13522.2|Contig4-2748_0004|orf6.1568|CA0566|CaO19.13630|CaO19.6252|IPF13522 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1411643 1413043 + orf19.6250 1411643 1413043 1 1411643 1413043 1411731 1412774 orf19.13628|IPF20917.1|IPF13526.2|Contig4-2748_0002|orf6.1566|CA0565|SCD6|CaO19.6250|CaO19.13628|IPF13526 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1413053 1415600 - orf19.6249 1413053 1415600 1 1415600 1413053 1415515 1413089 HAK1 orf19.13627|IPF20886.1|IPF9136.3|Contig4-2748_0001|Contig4-2748_0010|orf6.1565|orf6.2201|CA0966|IPF9136|IPF9136.5eoc|IPF9136.2 Putative potassium transporter; similar to Schwanniomyces occidentalis Hak1p; amphotericin B induced; transcriptionally induced upon phagocytosis by macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 1417268 1417969 - orf19.6248 1417268 1417969 1 1417969 1417268 1417969 1417268 orf19.13626|IPF20925.1|IPF9139.2|Contig4-2382_0002|orf6.2200|CA0965|CaO19.6248|IPF9139 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1418502 1421375 + orf19.6247 1418502 1421375 1 1418502 1421375 1418596 1421211 orf19.13625|IPF20880.1|IPF9141.2|Contig4-2635_0014|orf6.2199|CA0964|CTF4|CaO19.6247|IPF9141 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1421138 1421826 - ntar_131 1421138 1421826 1 1421826 1421138 1421581 1421438 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1421770 1422680 + orf19.6246 1421770 1422680 1 1421770 1422680 1421911 1422477 orf19.13624|IPF20930.1|IPF9143.1|Contig4-2635_0010|orf6.2198|CA0963|CaO19.6246|NAT3|CaO19.13624|IPF9143 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1422244 1422496 - ntar_132 1422244 1422496 1 1422496 1422244 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1422967 1424785 + orf19.6245 1422967 1424785 1 1422967 1424785 1422978 1424678 orf19.13623|IPF19079.2|IPF9145.2|Contig4-2635_0007|orf6.2197|orf6.985|CA0962|CaO19.6245|IPF9145 Predicted ORF in Assemblies 19, 20 and 21; regulated by osmotic stress (via Hog1p) and oxidative stress (Hog1p- and Cap1p-independent); transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1424364 1424585 - ntar_133 1424364 1424585 1 1424585 1424364 1424585 1424364 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1425038 1427781 + orf19.6244 1425038 1427781 1 1425038 1427781 1425396 1427717 orf19.13622|IPF9146.2|IPF18817.2|Contig4-2635_0006|orf6.2196|orf6.672|orf6.984|CA0251|IFH1|CaO19.6244|IPF9146 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1427944 1431149 + orf19.6243 1427944 1431149 1 1427944 1431149 1427968 1431030 VPS34 orf19.13621|IPF17928.3|IPF17276.2|Contig4-2635_0002|Contig4-2635_0003|orf6.5115|orf6.673|orf6.983|CA0149|CaO19.6243 Autophosphorylated phosphatidylinositol 3-kinase, class III, required for wild-type vesicle transport, hyphal growth, adherence to fibroblasts, and virulence in mouse systemic infection; low abundance mRNA, growth-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 1431455 1432983 + orf19.6242 1431455 1432983 1 1431455 1432983 1432024 1432983 IPF15741.2|IPF19190.1|orf6.5116|orf6.674|CA3003|CYK3|CaO19.6242|IPF15741.5f|IPF15741 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1432991 1435243 + orf19.6240 1432991 1435243 1 1432991 1435243 1433503 1435086 orf19.13620|IPF15741.2|IPF19687.2|orf6.904|orf6.5116|CA6304|CA6308|orf19.6241|IPF15741.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1435382 1436528 + orf19.6239 1435382 1436528 1 1435382 1436528 1435444 1436475 orf19.13619|IPF15293.1|IPF15740.2|Contig4-1996_0006|orf6.5117|orf6.903|CA3004|KIN28|CaO19.6239 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1436376 1437759 - orf19.6238 1436376 1437759 1 1437759 1436376 1437711 1436509 orf19.13618|IPF20916.1|IPF15294.2|Contig4-1996_0005|orf6.5118|orf6.902|CA0218|CaO19.6238|IPF15294 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1439922 1441494 + orf19.6237 1439922 1441494 1 1439922 1441494 1440150 1440860 RAC1 orf19.13617|IPF19967.1|IPF27772.1|Contig4-2906_0002|Contig4-2906_0003|orf6.5119|CA3005|CaO19.6237|CDC422|CaO19.13617|CC43 G-protein of RAC subfamily; required for embedded filamentous growth, but not for serum-induced hyphal growth; dynamic localization at plasma membrane; similar to, but not interchangeable with, Cdc42p; lacks S. cerevisiae homolog [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1441238 1442176 - orf19.6236 1441238 1442176 1 1442176 1441238 1442123 1441494 orf19.13616|IPF12152.1|IPF12514.2|Contig4-2906_0005|orf6.5120|CA3006|CaO19.6236|IPF12152 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1442300 1442943 + orf19.6235 1442300 1442943 1 1442300 1442943 1442352 1442738 orf19.13615|IPF12150.1|IPF12515.2|Contig4-2906_0006|orf6.1583|orf6.5121|CaO19.6235 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1442798 1444495 - orf19.6234 1442798 1444495 1 1444495 1442798 1444495 1442891 orf19.13614|IPF12148.1|IPF12516.1|Contig4-2906_0007|orf6.1584|orf6.5122|CA3007|CaO19.6234|IPF12148 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 1444504 1446115 + orf19.6233 1444504 1446115 1 1444504 1446115 1444504 1446027 orf19.13613|IPF12147.2|IPF12518.1|Contig4-1351_0001|Contig4-1351_0002|Contig4-2906_0010|orf6.1585|orf6.5123|CA3008|CaO19.6233|IPF12147 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 1446885 1449859 + orf19.6232 1446885 1449859 1 1446885 1449859 1447186 1449687 NPR1 orf19.13612|IPF20888.1|IPF12521.2|Contig4-2906_0015|orf6.1586|orf6.5124|CA0576|CaO19.6232 Predicted ORF in Assemblies 19, 20 and 21; induced in core stress response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1449779 1450444 - orf19.6231 1449779 1450444 1 1450444 1449779 1450368 1449937 MRPL19 orf19.13611|IPF14569.2|IPF12523.3|Contig4-2906_0017|orf6.1587|orf6.5125|CA3009|CaO19.6231 Protein described as a ribosomal protein; induced upon adherence to polystyrene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1450611 1451861 + orf19.6230 1450611 1451861 1 1450611 1451861 1450648 1451823 orf19.13610|IPF14568.2|IPF18936.2|Contig4-2906_0018|orf6.5126|CA3010|CaO19.6230|RAI1|CaO19.13610|IPF14568 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1453252 1455073 + orf19.6229 1453252 1455073 1 1453252 1455073 1453415 1454872 CAT1 orf19.13609|CCT1|CCT|orf6.5127|CTA1|IPF20907.1|IPF20124.1|Contig4-1984_0001|Contig4-2906_0020|CA3011|CaO19.13609|CaO19.6229 Catalase; role in resistance to oxidative stress, neutrophils, peroxide; role in murine systemic virulence; regulated by iron, ciclopirox olamine, fluconazole, growth, carbon source, pH, Rim101p, Ssn6p, Hog1p, farnesol, core stress response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1455437 1456730 + orf19.6227 1455437 1456730 1 1455437 1456730 1455604 1456596 orf19.13607|IPF20919.1|IPF14013.2|Contig4-1851_0006|Contig4-1851_0008|orf6.5129|CA3012|CaO19.13607|CaO19.6227|IPF14013 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1456893 1458031 + ntar_134 1456893 1458031 1 1456893 1458031 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1457026 1458175 - orf19.6225.1 1457026 1458175 1 1458175 1457026 1457571 1457278 IPF20970.1|IPF20125.1|Contig4-1851_0004|CA3013|PET117 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1458782 1461611 + orf19.6225 1458782 1461611 1 1458782 1461611 1459337 1461391 PCL7 orf19.13605|IPF11915.2|IPF18998.2|Contig4-2759_0013|orf6.1290|orf6.5131|CA3014|CaO19.6225|IPF11915 Protein described as cyclin-like, possible Pho85p cyclin; hyphal downregulated; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1462779 1464272 + orf19.6224 1462779 1464272 1 1462779 1464272 1462779 1464272 orf19.13604|IPF20910.1|IPF11914.1|Contig4-2759_0009|orf6.1289|CA0401|CaO19.6224|RSB14|CaO19.13604|RTA1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr1 1464285 1464830 - orf19.6222.1 1464285 1464830 1 1464830 1464285 1464706 1464503 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1465246 1468296 - orf19.6222 1465246 1468296 4 1468296|1468187|1465496|1465329 1468248|1465580|1465409|1465246 1468296 1465246 SPO22 orf19.13603|IPF7423.3|IPF27762.1|Contig4-2759_0006|orf6.4534|orf6.1288|CA6303|CA0400|orf19.6223|IPF7423.5f Predicted ORF in Assemblies 19, 20 and 21; similar to S. cerevisiae Spo22p [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1468392 1469495 - orf19.6220.4 1468392 1469495 2 1469495|1468865 1469308|1468392 1469344 1468534 IPF20959.1|IPF7424.1|Contig4-2759_0004|CA2579|RPL34B.3 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1469531 1470343 - orf19.6220.3 1469531 1470343 3 1470343|1470184|1470034 1470263|1470124|1469531 1470343 1469706 MMD1 IPF20961.1|IPF7427.2|CA2578|MMD1.3 ORF Predicted by Annotation Working Group; macrophage-downregulated protein abundance [label_first_exon=CGD label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1470501 1473313 - orf19.6220 1470501 1473313 1 1473313 1470501 1473250 1470554 orf19.13601|IPF20879.1|IPF7430.2|orf6.4532|CA2577|CaO19.13601|CAF130|CaO19.6220|IPF7430 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1473411 1475045 - orf19.6219 1473411 1475045 1 1475045 1473411 1474919 1473564 orf19.13600|IPF20909.1|IPF7432.2|Contig4-2632_0002|orf6.4531|CA2576|CaO19.6219|CaO19.13600|IPF7432 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1475533 1479772 + orf19.6217 1475533 1479772 1 1475533 1479772 1475717 1479514 PGA63 orf19.13598|orf19.13597|IPF20958.1|IPF7439.2|Contig4-2632_0006|orf6.4528|orf6.4529|CA2575|orf19.6216|CaO19.13598|SEC31|CaO19.6217 Putative protein of unknown function [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1479644 1483225 - orf19.6214 1479644 1483225 1 1483225 1479644 1483049 1479813 ATC1 orf19.13595|IPF19760|ATH1|IPF20966.1|IPF19760.1|Contig4-1596_0001|Contig4-2632_0007|orf6.4526|CA2574|CaO19.6214|CaO19.13595 Cell wall acid trehalase; catalyzes hydrolysis of the disaccharide trehalose; similar to S. cerevisiae vacuolar acid trehalase (Ath1p) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 1483537 1484150 - tp(agg)1 1483537 1484150 2 1484150|1484075 1484114|1483537 1483828 1483604 tP(AGG)1.2 tRNA-Pro predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGDmod orf_changed=true scenario_first_exon=Z scenario_last_exon=D] Ca21chr1 1484787 1485890 + orf19.6213 1484787 1485890 1 1484787 1485890 1484830 1485732 SUI2 orf19.13594|IPF20923.1|IPF13764.2|Contig4-2125_0001|orf6.4525|CA2573|CaO19.13594|CaO19.6213 Putative translation initiation factor; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1485741 1487601 - orf19.6211 1485741 1487601 1 1487601 1485741 1487542 1485887 orf19.13592|IPF20905.1|IPF13766.2|Contig4-2125_0002|Contig4-2125_0003|orf6.4523|CA2572|CaO19.13592|PTE99|CaO19.6211|IPF13766 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1487721 1489281 - orf19.6209 1487721 1489281 1 1489281 1487721 1489211 1487778 orf19.13590|IPF13769.1|IPF13767.3|Contig4-2125_0004|orf6.4521|orf6.5415|CA2571|CaO19.6209|IPF13769 Predicted membrane transporter, member of the monocarboxylate porter (MCP) family, major facilitator superfamily (MFS) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1487960 1489190 + ntar_135 1487960 1489190 1 1487960 1489190 1488412 1488834 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1489673 1489788 - tl(uaa)4 1489673 1489788 2 1489788|1489718 1489750|1489673 tL(UAA)4.2 tRNA-Leu predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1490336 1492913 + orf19.6208 1490336 1492913 1 1490336 1492913 1490379 1492802 MEF2 orf19.13589|IPF20891.1|IPF8163.1|Contig4-2876_0010|orf6.5416|CA3212|CaO19.6208 Predicted ORF in Assemblies 19, 20 and 21; caspofungin induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1493074 1494190 + orf19.6205 1493074 1494190 1 1493074 1494190 1493138 1494094 orf19.13586|IPF20921.1|IPF8160.1|Contig4-2876_0011|Contig4-2876_0012|orf6.5419|CA3213|CaO19.6205|CaO19.13586|IPF8160 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1494081 1497275 - orf19.6203 1494081 1497275 1 1497275 1494081 1497140 1494204 PUT3|orf19.13584|IPF19238.2|IPF8158.2|Contig4-2876_0013|orf6.536|orf6.5421|CA3214|CaO19.6203 Predicted zinc-finger protein of unknown function; has similarity to S. cerevisiae Put3p, which is a transcription factor involved in the regulation of proline utilization genes [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1497797 1499186 - orf19.6202 1497797 1499186 1 1499186 1497797 1499055 1497979 RBT4 orf19.13583|orf6.537|YJL79|PRY4|IPF8153.3|IPF27769.1|Contig4-2876_0017|orf6.5422|CA0104|IPF8153.2 Protein with similarity to plant pathogenesis-related proteins; required for virulence in mouse systemic and rabbit corneal infections; not required for filamentation; mRNA binds to She3p and is localized to hyphal tips [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1502242 1503195 - orf19.6200 1502242 1503195 1 1503195 1502242 1503195 1502242 orf19.13580|IPF8147.2|IPF27770.1|Contig4-2022_0012|Contig4-2612_0003|orf6.5424|orf6.929|CA0229|CaO19.6200|IPF8147 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1504743 1507494 - orf19.6199 1504743 1507494 2 1507494|1507055 1507434|1504743 1507029 1504870 orf19.13579|IPF20894.1|IPF13040.1|Contig4-2612_0009|orf6.5425|CA3215|CaO19.6199|HCS1|CaO19.13579 Predicted ORF in Assemblies 19, 20 and 21; intron in 5'-UTR [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=A] Ca21chr1 1507584 1508460 - orf19.6198.1 1507584 1508460 2 1508460|1508123 1508331|1507584 1508336 1507818 IPF20969.1|IPF13038.1|Contig4-2612_0013|CA3216|IPF13038.3f|IPF13038 Predicted ORF in Assemblies 19, 20 and 21; gene has intron; gene was predicted by Annotation Working Group (AWG), subsequently removed from Assembly 20 by the AWG, and later reinstated (see Locus History) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1508968 1511996 - orf19.6197 1508968 1511996 1 1511996 1508968 1511622 1509973 orf19.13577|IPF20903.1|IPF19979.1|Contig4-2590_0004|Contig4-2590_0005|orf6.5427|CA3217|CaO19.13577|DHH1|CaO19.6197 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1513182 1514134 + orf19.6196 1513182 1514134 1 1513182 1514134 1513343 1513909 orf19.13576|IPF20931.1|IPF10005.1|Contig4-2590_0009|orf6.5428|CA3218|CaO19.13576|CaO19.6196|IPF10005 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1514119 1516522 - orf19.6195 1514119 1516522 1 1516522 1514119 1516388 1514154 orf19.13575|IPF20893.1|IPF10003.2|Contig4-2590_0011|orf6.5429|CA3219|RNH70|CaO19.6195|CaO19.13575|IPF10003 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1516632 1517852 - orf19.6194 1516632 1517852 1 1517852 1516632 1517800 1516859 orf19.13574|IPF10001|IPF20922.1|IPF10001.2|Contig4-1805_0002|orf6.5430|CA3220|CaO19.13574|CaO19.6194 Protein not essential for viability; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1516894 1517647 + ntar_136 1516894 1517647 1 1516894 1517647 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1518217 1522248 + orf19.6193 1518217 1522248 1 1518217 1522248 1518264 1522049 TAF145 orf19.8354|orf19.13573|IPF20901.1|IPF10000.2|IPF26567.1|IPF16558.2|orf6.996|orf6.5431|TAF1|CA3221|CA0255|orf19.735|IPF10000.5eoc Protein likely to be essential for growth, based on an insertional mutagenesis strategy; similar to S. cerevisiae Taf145p, which is a component of RNA polymerase II transcription factor TFIID; flucytosine repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1526789 1529011 + orf19.4456 1526789 1529011 1 1526789 1529011 1527013 1528836 GAP4 orf19.11936|IPF22804.1|IPF6541.2|GAP5|Contig4-1998_0001|orf6.7269|CA4667|GAP31|CaO19.11936|CaO19.4456 Putative amino acid permease; hyphal induced; regulated by Gcn2p and Gcn4p; shows colony morphology-related gene regulation by Ssn6p; detected at plasma membrane of yeast-form and germ tube by mass spectrometry [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1528932 1531089 - orf19.4455 1528932 1531089 1 1531089 1528932 1530826 1529021 orf19.11935|IPF22807.1|IPF6542.1|Contig4-1998_0002|orf6.7268|CA4666|CaO19.4455|CaO19.11935|IPF6542 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1531303 1534700 - orf19.4451 1531303 1534700 1 1534700 1531303 1534645 1531511 RIA1 orf19.11931|IPF22841.1|IPF6548.2|Contig4-1998_0005|Contig4-2531_0013|orf6.7264|CA4665|CaO19.4451|CaO19.11931|IPF6548 Putative translation elongation factor; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1534771 1535250 + orf19.4450.2 1534771 1535250 1 1534771 1535250 1534840 1535082 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1535085 1535751 - orf19.4450.1 1535085 1535751 1 1535751 1535085 1535433 1535227 IPF22833.1|IPF6551.2|Contig4-2531_0010|CA4664|IPF6551.3f ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1536562 1538879 - orf19.4450 1536562 1538879 1 1538879 1536562 1538464 1536764 ZCF23|orf19.11930|IPF18188.2|IPF6554.2|Contig4-2531_0005|Contig4-2531_0007|orf6.7263|CA4663|CaO19.11930|CaO19.4450|IPF6554 Predicted zinc-finger protein of unknown function [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1540711 1541744 + orf19.4449 1540711 1541744 1 1540711 1541744 1540755 1541501 orf19.11929|IPF22817.1|IPF6557.1|orf6.7262|CA4662|CaO19.4449|LYS7|CaO19.11929 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1542061 1544916 + orf19.4448 1542061 1544916 1 1542061 1544916 1542293 1544758 SOG2 orf19.11928|IPF22794.1|IPF6561.2|Contig4-2378_0006|orf6.7261|CA4661|CaO19.11928|CaO19.4448|IPF6561 Leucine-rich-repeat domain protein of RAM cell wall integrity signaling network; role in cell separation, azole sensitivity; required for hyphal growth; lacks orthologs in higher eukaryotes [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1545416 1546445 + orf19.4447 1545416 1546445 1 1545416 1546445 1545462 1546361 YMC1 orf19.11927|IPF22816.1|IPF6563.1|Contig4-2378_0001|orf6.7260|CA4660|CaO19.4447|CaO19.11927 Predicted ORF in Assemblies 19, 20 and 21; flucytosine induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1546298 1548251 - orf19.4446 1546298 1548251 1 1548251 1546298 1548214 1546472 orf19.11926|IPF22808.1|IPF17754.2|orf6.7259|CA4659|CaO19.4446|CaO19.11926|IPF17754 Protein similar to ammomium permeases that is probably inactive, as a mep2 mep3 double homozygous null mutation abolishes cellular ammomium permease activity; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1549779 1551488 + orf19.4445 1549779 1551488 1 1549779 1551488 1549838 1551466 orf19.11925|IPF22811.1|IPF3092.1|Contig4-2907_0018|orf6.7258|CA4658|CaO19.11925|CaO19.4445|IPF3092 Predicted ORF in Assemblies 19, 20 and 21; Plc1p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1551742 1552829 + orf19.4444 1551742 1552829 1 1551742 1552829 1551791 1552717 PHO15 orf19.11924|IPF22814.1|IPF3094.1|Contig4-2907_0015|orf6.7257|CA4657|CaO19.4444|PHO131|CaO19.11924|PHO13|IPF3094 Protein described as 4-nitrophenyl phosphatase, possible histone H2A phosphatase; involved in regulation of white-opaque switching; hyphal downregulated; induced in core stress response; induced by heavy metal (cadmium) stress via Hog1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1552764 1553020 - ntar_137 1552764 1553020 1 1553020 1552764 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1553448 1554293 + orf19.4443 1553448 1554293 1 1553448 1554293 1553589 1554143 YPD1 orf19.11923|orf6.7256|IPF22818.1|IPF3095.1|Contig4-2907_0011|CA4656|CaO19.4443|CaO19.11923|IPF3095 Phosphohistidine intermediate protein in a phosphorelay signal transduction pathway; residue His69 is the phosphoacceptor histidine; predicted to be soluble and cytosolic; functional homolog of S. cerevisiae Ypd1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1554098 1556036 - orf19.4442 1554098 1556036 1 1556036 1554098 1555985 1554303 ALG9 orf19.11922|IPF22809.1|IPF3098.2|Contig4-2907_0010|orf6.7255|CA4655|CaO19.11922|CaO19.4442|IPF3098 Putative mannosyltransferase; similar to S. cerevisiae Alg9p; has HKEXRF motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1556141 1558033 - orf19.4441 1556141 1558033 1 1558033 1556141 1557966 1556170 orf19.11921|IPF22806.1|IPF3101.1|Contig4-2907_0006|Contig4-2907_0007|orf6.7254|CA4654|CaO19.11921|DNA43|CaO19.4441|IPF3101 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1558150 1560770 + orf19.4440 1558150 1560770 1 1558150 1560770 1558202 1560721 SEC34 orf19.11920|IPF22793.1|IPF3102.1|Contig4-2907_0005|orf6.7253|CA4653|COG3|CaO19.4440|CaO19.11920|IPF3102 Protein not essential for viability; similar to S. cerevisiae Cog3p, which is a component of the conserved oligomeric Golgi complex involved in intracellular protein trafficking [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1560496 1561175 - orf19.4439.1 1560496 1561175 1 1561175 1560496 1560986 1560777 IPF22795.1|IPF3103.2|orf6.3230 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1561038 1561481 + orf19.4439 1561038 1561481 1 1561038 1561481 1561038 1561481 orf19.11919|IPF22822.1|IPF3105.2|Contig4-2907_0004|orf6.7252|CA4652|CaO19.11919|CaO19.4439|IPF3105 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1569740 1570173 - tl(aag)2 1569740 1570173 2 1570173|1570098 1570137|1569740 1570167 1569962 tL(AAG)2.2 tRNA-Leu predicted by tRNAscan-SE; has atypical G at position 32 [label_first_exon=CGD label_last_exon=CGDmod orf_changed=true scenario_first_exon=Z scenario_last_exon=D] Ca21chr1 1570906 1571473 + ntar_138 1570906 1571473 1 1570906 1571473 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1571384 1571662 - ntar_139 1571384 1571662 1 1571662 1571384 1571557 1571384 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1573775 1574044 + ntar_140 1573775 1574044 1 1573775 1574044 1573775 1573897 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1578359 1580772 + orf19.4438 1578359 1580772 1 1578359 1580772 1578967 1580490 RME1 orf19.11918|IPF3121|IPF3121.1|IPF28396.1|Contig4-3008_0024|orf6.7251|CA4651|CaO19.4438 Protein similar to S. cerevisiae meiotic regulator Rme1p; white-specific transcription; upregulation correlates with clinical development of fluconazole resistance; transcription is not regulated during rat oral infection [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1580496 1581040 - ntar_141 1580496 1581040 1 1581040 1580496 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1581182 1584450 + orf19.4437 1581182 1584450 2 1581182|1581323 1581252|1584450 1581235 1584358 orf19.11916|IPF9859.2|IPF28412.1|Contig4-3008_0028|Contig4-3008_0029|orf6.7249|CA4650|ISW1|ISW1.3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1583991 1584993 - orf19.4436 1583991 1584993 1 1584993 1583991 1584935 1584381 orf19.11915|IPF22819.1|IPF9860.2|Contig4-3008_0031|orf6.7248|CA4649|GPX2|CaO19.11915|CaO19.4436|GPX4 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1585872 1590148 + orf19.4435 1585872 1590148 1 1585872 1590148 1586011 1589922 orf19.11914|IPF9864.1|IPF28404.1|Contig4-3008_0033|orf6.7247|CA4648|STU1|CaO19.11914|CaO19.4435|IPF9864 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1590535 1593032 - orf19.4433 1590535 1593032 1 1593032 1590535 1592574 1590604 CPH1 orf19.11912|APRP1|ACPR1|ACPR|IPF9866.3|IPF5536.2|Contig4-2476_0010|orf6.2724|orf6.695|orf6.7245|CA0154|CaO19.4433 Transcription factor required for mating and hyphal growth on solid media; with Efg1p required for host cytokine response; in filamentation pathway with Ess1p and Czf1p; regulates genes of galactose metabolism [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 1593608 1593860 - ntar_142 1593608 1593860 1 1593860 1593608 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1594949 1598365 - orf19.4432 1594949 1598365 1 1598365 1594949 1598119 1595267 KSP1 orf19.11910|IPF22791.1|IPF5540.2|Contig4-2969_0018|orf6.2723|CA1288|CaO19.11910|CaO19.4432 Putative protein of unknown function; mRNA binds to She3p and is localized to hyphal tips; mutation confers hypersensitivity to amphotericin B; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 1598525 1598954 - ntar_143 1598525 1598954 1 1598954 1598525 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1599231 1599949 + ntar_144 1599231 1599949 1 1599231 1599949 1599811 1599933 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1600014 1600152 - ntar_145 1600014 1600152 1 1600152 1600014 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1600347 1602209 + orf19.4430 1600347 1602209 1 1600347 1602209 1600458 1602098 orf19.11908|IPF22812.1|IPF5545.2|Contig4-2969_0013|Contig4-2969_0014|orf6.2721|CA1287|CaO19.4430|CaO19.11908|IPF5545 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1601968 1604141 - orf19.4428 1601968 1604141 1 1604141 1601968 1603689 1602250 orf19.11906|IPF5546|IPF5546.1|IPF28397.1|Contig4-2969_0012|orf6.2719|CA1286|CaO19.11906|CaO19.4428 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1604326 1605072 - orf19.4427 1604326 1605072 1 1605072 1604326 1605009 1604515 SKP1 orf19.11905|IPF5549.2|IPF28398.1|Contig4-2969_0008|orf6.2718|orf6.2827|CA1285|CaO19.4427 Protein described as subunit D of kinetochore protein complex CBF3; regulated by Gcn4p; repressed in response to amino acid starvation (3-aminotriazole treatment) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1605244 1607095 - orf19.4426 1605244 1607095 1 1607095 1605244 1606830 1605439 PEX3 orf19.11904|IPF18715.2|IPF5552.2|Contig4-2969_0007|orf6.2717|orf6.2828|CA1362|CaO19.4426 Putative peroxisomal protein involved in targeting proteins into peroxisomes [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1609129 1610100 + orf19.4424 1609129 1610100 1 1609129 1610100 1609129 1610100 PHO100 orf19.11902|IPF22815.1|IPF5556.1|PHO3|Contig4-2969_0004|orf6.2830|CA1363|CaO19.4424|CaO19.11902|IPF5556 Putative inducible acid phosphatase; DTT-extractable and observed in culture supernatant under low-phosphate conditions; slight effect on murine virulence; induced on biofilm formation; virulence-group-correlated expression; N-glycosylated [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1610137 1610698 - ntar_146 1610137 1610698 1 1610698 1610137 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1610930 1614440 + orf19.4423 1610930 1614440 1 1610930 1614440 1611087 1614308 orf19.11901|IPF22836.1|IPF5561.2|Contig4-2969_0001|Contig4-2969_0002|orf6.2831|CA1364|CaO19.4423|CaO19.11901|IPF5561 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1615586 1615745 + ntar_147 1615586 1615745 1 1615586 1615745 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1615671 1616981 - orf19.2799 1615671 1616981 1 1616981 1615671 1616916 1615765 GPI8 orf19.10317|IPF24553.1|IPF11799.2|Contig4-2693_0008|orf6.3728|CA2007|CaO19.2799|CaO19.10317 Protein likely to be essential for growth, based on an insertional mutagenesis strategy; similar to S. cerevisiae Gpi8p, which is a subunit of the GPI transamidase complex that adds GPI anchors to proteins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1617137 1619172 - orf19.2798 1617137 1619172 1 1619172 1617137 1619149 1617182 orf19.10316|IPF24546.1|IPF11801.2|Contig4-2693_0007|orf6.3727|CA2006|CaO19.10316|CaO19.2798|IPF11801 Putative helicase; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1619388 1621259 - orf19.2797 1619388 1621259 1 1621259 1619388 1621259 1619388 orf19.10315|IPF24549.1|IPF11802.2|Contig4-2693_0005|orf6.3726|CA2005|CaO19.2797|CaO19.10315|IPF11802 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1621401 1623540 - orf19.2796 1621401 1623540 1 1623540 1621401 1623502 1621508 orf19.10314|IPF24548.1|IPF15718.2|Contig4-2693_0003|orf6.3725|CA2004|CaO19.2796|POL12 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1623766 1624990 - orf19.2795 1623766 1624990 1 1624990 1623766 1624898 1623924 orf19.10313|IPF24554.1|IPF16471.1|Contig4-1628_0003|orf6.3724|CA2003|LHP1|CaO19.2795|IPF16471 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1625216 1626196 + orf19.2794 1625216 1626196 1 1625216 1626196 1625260 1626093 orf19.10312|IPF24557.1|IPF16470.2|Contig4-1628_0004|Contig4-1676_0002|orf6.3723|YDL219W|CA2002|CaO19.10312|CaO19.2794|IPF16470 Protein regulated by Gcn4p; repressed in response to amino acid starvation (3-aminotriazole treatment); alkaline upregulated; macrophage-induced protein [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1626180 1629427 - orf19.2792 1626180 1629427 1 1629427 1626180 1629144 1626286 IST2 orf19.10310|IPF7245.3|IPF17074.2|Contig4-2218_0006|orf6.3611|orf6.3721|CA2001|CaO19.2792|IPF17074 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1630691 1630786 + orf19.2800 1630691 1630786 1 1630691 1630786 Predicted ORF in Assembly 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1631014 1631370 - ntar_148 1631014 1631370 1 1631370 1631014 1631370 1631167 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1631779 1634913 - orf19.2791 1631779 1634913 1 1634913 1631779 1634762 1631898 orf19.10309|IPF7255.2|IPF11796.1|Contig4-2483_0003|Contig4-2693_0010|orf6.3608|orf6.3610|orf6.3720|CA2000|CaO19.2791|IPF11796 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1635101 1636526 + orf19.2790 1635101 1636526 1 1635101 1636526 1635240 1636334 SWD2 orf19.10306|IPF7260.1|IPF11792.2|Contig4-2384_0002|Contig4-2384_0003|orf6.3607|orf6.3719|CA1910|CaO19.10306|CaO19.2790|IPF7260 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1636441 1636839 - ntar_149 1636441 1636839 1 1636839 1636441 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1636935 1638010 + orf19.2789 1636935 1638010 1 1636935 1638010 1636942 1637901 orf19.10305|IPF24555.1|IPF7262.2|Contig4-2384_0004|orf6.3606|orf6.977|CA0248|CaO19.2789|IPF7262 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1637880 1639192 - orf19.2788 1637880 1639192 1 1639192 1637880 1639135 1637927 orf19.10304|IPF24552.1|IPF7263.2|Contig4-2384_0005|Contig4-2384_0007|orf6.3605|orf6.976|CA0247|CaO19.2788|RIB21 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1639483 1640851 - orf19.2787 1639483 1640851 1 1640851 1639483 1640814 1639582 PRY1 orf19.10303|IPF20091.1|IPF20053.1|Contig4-2384_0008|orf6.3604|orf6.975|CA1909|CaO19.2787|IPF20091 Transcription is opaque specific; transcription is repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1641901 1645390 - orf19.2786 1641901 1645390 1 1645390 1641901 1645192 1642067 orf19.10302|IPF24565.1|IPF7268.2|Contig4-2533_0009|orf6.3603|CA1908|APL3|CaO19.2786|CaO19.10302 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1645584 1646560 + orf19.2785 1645584 1646560 1 1645584 1646560 1645704 1646228 ATP7 orf19.10301|IPF24558.1|IPF7270.1|orf6.3602|CA1907|CaO19.2785|CaO19.10301 Putative subunit of the F1F0-ATPase complex; shows colony morphology-related gene regulation by Ssn6p; farnesol-, macrophage-downregulated protein abundance [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1646326 1647328 - orf19.2784 1646326 1647328 1 1647328 1646326 1647328 1646384 orf19.10300|IPF24556.1|IPF7271.1|Contig4-2533_0003|Contig4-2533_0004|orf6.3601|CA1906|CaO19.2784|CaO19.10300|IPF7271 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 1647588 1648207 + ntar_150 1647588 1648207 1 1647588 1648207 1647989 1648207 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1647638 1648912 - orf19.2783 1647638 1648912 1 1648912 1647638 1648912 1647638 PIR32 orf19.10299|IPF24551.1|IPF7274.2|Contig4-2533_0002|orf6.3600|CA1905|CaO19.10299|PIR3|CaO19.2783|IPF7274 [NOT TRANSCRIBED?] Protein described as putative cell wall structural component; macrophage-induced gene [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1649634 1650560 + orf19.2782 1649634 1650560 1 1649634 1650560 1649731 1650258 orf19.10298|IPF7275.2|IPF19489.2|Contig4-2533_0001|orf6.14|orf6.3599|CA1904|CaO19.10298|GRX5|CaO19.2782 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1650887 1651487 + ntar_151 1650887 1651487 1 1650887 1651487 1651236 1651487 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1651229 1654072 - orf19.2781 1651229 1654072 1 1654072 1651229 1653745 1651229 orf19.10297|IPF14089.2|IPF19488.2|Contig4-2630_0016|orf6.15|orf6.859|CA0206|CaO19.2781|IPF14089 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr1 1656963 1659084 - ntar_152 1656963 1659084 1 1659084 1656963 1659046 1658867 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1658949 1659461 + orf19.2779 1658949 1659461 1 1658949 1659461 1658949 1659461 orf19.10295|orf19.10296|IPF24559.1|IPF16330.2|Contig4-2630_0002|orf6.1476|orf6.1477|orf19.2780|CaO19.2779|CaO19.10295 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1659233 1659876 - ntar_153 1659233 1659876 1 1659876 1659233 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1660182 1663440 + orf19.2778 1660182 1663440 1 1660182 1663440 1660272 1662500 orf19.8812|orf19.10294|IPF26069.1|IPF18002.2|IPF24547.1|IPF16466.1|orf6.866|orf6.1475|CA0207|CA0504|orf19.1226|IPF16466.5eoc|IPF16466 Putative protein of unknown function, transcription is upregulated in clinical isolates from HIV+ patients with oral candidiasis; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 1663582 1666070 + ntar_154 1663582 1666070 1 1663582 1666070 1664365 1665960 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1666503 1667093 + orf19.1227 1666503 1667093 1 1666503 1667093 1666503 1667093 ZCF4|orf19.8813|IPF26088.1|IPF19850.1|Contig4-1474_0002|orf6.867|CA0208|CaO19.8813|CaO19.1227|IPF19850 Putative transcription factor with zinc cluster DNA-binding motif; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1667987 1669667 + orf19.1228 1667987 1669667 1 1667987 1669667 1668206 1669300 HAP2 orf19.8814|IPF18396.2|IPF16519.2|orf6.5088|orf6.868|CA0209|CaO19.1228|CA2983|IPF18396|IPF18396.1 CCAAT-binding factor regulates low-iron (chelation) induction of FRP1 transcription, and under these conditions CBF comprises Hap43p and probably Hap2p and Hap3p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1669635 1673221 - orf19.1229 1669635 1673221 1 1673221 1669635 1672965 1669828 orf19.8815|orf19.8816|IPF16520.2|IPF26077.1|IPF19119.2|IPF29521.1|IPF13285.2|Contig4-1270_0001|Contig4-1270_0002|Contig4-2208_0002|orf6.5087|orf6.869|orf6.5086|CA6253|CA2982|CA2981|orf19.1230|orf19.1231|CSE1.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 1673375 1674265 + ntar_155 1673375 1674265 1 1673375 1674265 1674089 1674265 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1673923 1675468 - orf19.1232 1673923 1675468 1 1675468 1673923 1675356 1674241 VRG4 orf19.8817|IPF26079.1|IPF13284.2|Contig4-2208_0006|orf6.5085|CA2980|CaO19.1232|CaO19.8817|GOG5 GDP-mannose transporter; essential; required for glycosylation, hyphal growth; functional homolog of S. cerevisiae Vrg4p, which imports GDP-mannose from cytoplasm to Golgi for protein and lipid mannosylation; no mammalian homolog [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1676908 1678950 - orf19.1233 1676908 1678950 1 1678950 1676908 1678759 1677134 ADE4 orf19.8818|IPF26073.1|IPF13283.2|Contig4-1515_0003|orf6.5084|CA2979|CaO19.1233|CaO19.8818 Predicted ORF in Assemblies 19, 20 and 21; flucytosine induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1680602 1680836 - ntar_156 1680602 1680836 1 1680836 1680602 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1685048 1685239 - ntar_157 1685048 1685239 1 1685239 1685048 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1691374 1692912 + orf19.4712 1691374 1692912 1 1691374 1692912 1691374 1692912 FGR6-3 IPF12868.1|orf6.1877|orf6.3125|CA1562|CaO19.4712|IFV12 Protein lacking an ortholog in S. cerevisiae; member of a family encoded by FGR6-related genes in the RB2 repeat sequence; transposon mutation affects filamentous growth [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1696330 1699443 + orf19.4713 1696330 1699443 1 1696330 1699443 1696389 1699295 orf19.12514|IPF13855.2|IPF22154.1|IPF10881.2|orf6.3126|orf6.3389|CA1563|orf19.5047|IPF13855.5eoc|IPF13855 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1699215 1700299 - orf19.5049 1699215 1700299 1 1700299 1699215 1700264 1699335 orf19.12516|IPF22145.1|IPF10884.1|Contig4-2722_0002|orf6.3387|CA1747|CaO19.5049|CaO19.12516|IPF10884 Predicted ORF in Assemblies 19, 20 and 21; induced upon biofilm formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1700415 1702662 + orf19.5050 1700415 1702662 1 1700415 1702662 1700480 1702567 MTO1 orf19.12517|IPF22121.1|IPF10886.2|Contig4-2722_0003|orf6.3386|CA1746|CaO19.12517|CaO19.5050|IPF10886 Predicted ORF in Assemblies 19, 20 and 21; transcription is upregulated in both intermediate and mature biofilms [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1702547 1705070 - orf19.5051 1702547 1705070 1 1705070 1702547 1704918 1702648 orf19.12518|IPF22116.1|IPF10888.1|Contig4-2722_0004|orf6.3385|CA1745|CaO19.5051|CaO19.12518|IPF10888 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1705129 1706945 + orf19.5052 1705129 1706945 1 1705129 1706945 1705203 1706363 orf19.12519|IPF22139.1|IPF10889.1|Contig4-2722_0005|orf6.3384|CA1744|CaO19.5052|CaO19.12519|IPF10889 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1706365 1707330 - orf19.5053 1706365 1707330 1 1707330 1706365 1707228 1706446 orf19.12520|IPF22150.1|IPF12209.2|Contig4-2722_0006|orf6.3383|CA1743|ECO1|CaO19.12520|CaO19.5053|IPF12209 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1707411 1708576 + orf19.5054 1707411 1708576 1 1707411 1708576 1707564 1708466 orf19.12521|IPF22146.1|IPF12210.2|orf6.3382|CA1742|CaO19.5054|IPF12210 Putative quinolinate phosphoribosyl transferase, involved in NAD biosynthesis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1708327 1710028 - orf19.5056 1708327 1710028 1 1710028 1708327 1709964 1708525 orf19.12523|IPF12212.3|IPF28152.1|Contig4-2407_0008|Contig4-2407_0009|orf6.17|orf6.3380|CA0002|CaO19.5056|APC10|DOC1|IPF12212.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1710157 1711669 + orf19.5057 1710157 1711669 1 1710157 1711669 1710213 1711466 orf19.12524|IPF19487.2|IPF12213.2|Contig4-2407_0007|orf6.16|orf6.3379|CA1741|CaO19.5057|IPF12213 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1711544 1713692 - orf19.5058 1711544 1713692 1 1713692 1711544 1713620 1711758 SMI1 orf19.12525|IPF22129.1|IPF12215.2|Contig4-2407_0002|Contig4-2407_0003|orf6.3378|CA1740|CaO19.5058 Decreased mRNA abundance observed in cyr1 homozygous null mutant hyphal cells; caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1714361 1714672 + ntar_158 1714361 1714672 1 1714361 1714672 1714506 1714637 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1714577 1717207 - orf19.5059 1714577 1717207 1 1717207 1714577 1717055 1714737 GCS1 orf19.12526|orf19.12527|orf6.1606|GSH1|IPF12218.2|IPF28150.1|orf6.3377|orf6.1607|CA0583|CA6219|CA0584|orf19.5060|GSH1.53f|GSH1.3f|GSH1.exon2 Gamma-glutamylcysteine synthetase; enzyme of glutathione synthesis; similar to Hansenula polymorpha Gsh2p; induced on early/intermediate biofilm formation, in low iron, H2O2, Cd, or presence of human neutrophils; possibly adherence-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1717787 1718279 - ntar_159 1717787 1718279 1 1718279 1717787 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1718441 1721156 - orf19.5061 1718441 1721156 1 1721156 1718441 1720995 1718587 ADE5,7 orf19.12528|IPF13495.2|IPF19378.2|Contig4-1920_0002|orf6.1608|orf6.238|CA6294|CA0585|orf19.5062|"ADE5|7.3f" Enzyme of adenine biosynthesis; interacts with Vps34p; required for hyphal growth and virulence; flucytosine induced; not induced during GCN response, in contrast to the S. cerevisiae ortholog [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1722833 1723616 + orf19.5063 1722833 1723616 1 1722833 1723616 1722918 1723493 orf19.12529|IPF17932.1|IPF13493.1|Contig4-1378_0002|Contig4-1944_0005|orf6.1609|orf6.468|CA0586|CaO19.5063|IPF13493 Predicted ORF in Assemblies 19, 20 and 21; ciclopirox olamine induced; regulated by Ssn6p; induced by nitric oxide in yhb1 mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1723604 1725171 - orf19.5064 1723604 1725171 1 1725171 1723604 1725072 1723858 MRPL3 orf19.12530|IPF22138.1|IPF19552.2|Contig4-1944_0004|orf6.134|orf6.469|CA0089|CaO19.12530|CaO19.5064|IPF19552.1 Predicted ORF in Assemblies 19, 20 and 21; downregulated in core stress response; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1725713 1726402 + orf19.5064.1 1725713 1726402 1 1725713 1726402 1725751 1725942 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1726146 1727832 - orf19.5065 1726146 1727832 1 1727832 1726146 1727666 1726263 orf19.12531|IPF13488.2|IPF15606.2|Contig4-2050_0003|orf6.133|orf6.1522|CA0535|ERD1|CaO19.5065|IPF15606 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1728195 1728751 + ntar_160 1728195 1728751 1 1728195 1728751 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1728267 1729364 - ntar_161 1728267 1729364 1 1729364 1728267 1729336 1729208 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1729642 1730566 - orf19.5066 1729642 1730566 1 1730566 1729642 1730502 1729702 orf19.12532|IPF22148.1|IPF15607.1|Contig4-2050_0001|orf6.1521|CA0534|CaO19.12532|CaO19.5066|IPF15607 Predicted ORF in Assemblies 19, 20 and 21; essential; S. cerevisiae ortholog is essential [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1730636 1731522 + orf19.5067 1730636 1731522 1 1730636 1731522 1730783 1731481 orf19.12533|IPF22153.1|IPF19872.1|orf6.1520|CA0533|LRP1|CaO19.5067|CaO19.12533|IPF19872 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1731467 1735401 - orf19.5068 1731467 1735401 1 1735401 1731467 1735358 1731684 orf19.12534|IPF12318.3|IPF16157.2|Contig4-2885_0001|orf6.1519|orf6.2426|CA0532|IRE1|CaO19.5068 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1735791 1736125 + ntar_162 1735791 1736125 1 1735791 1736125 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1736568 1738498 - orf19.5069 1736568 1738498 1 1738498 1736568 1737864 1737133 orf19.12535|IPF12316.2|IPF19120.1|Contig4-2337_0002|orf6.2427|orf6.865|CA1098|CaO19.5069|IPF12316 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1739017 1739410 + ntar_163 1739017 1739410 1 1739017 1739410 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1739043 1739770 - ntar_164 1739043 1739770 1 1739770 1739043 1739769 1739647 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1740730 1740943 - ntar_165 1740730 1740943 1 1740943 1740730 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1741632 1741804 + ntar_166 1741632 1741804 1 1741632 1741804 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1741813 1743225 - orf19.5070 1741813 1743225 1 1743225 1741813 1743149 1741854 orf19.12536|orf6.2428|IPF12312.1|IPF28154.1|Contig4-1983_0002|Contig4-2337_0010|YOR009|CA1099|CaO19.5070|IPF12312 Predicted ORF in Assemblies 19, 20 and 21; transcriptionally regulated by iron; expression greater in low iron; similar to cell-wall mannoproteins; greater mRNA abundance observed in a cyr1 homozygous null mutant than in wild type; regulated by osmotic and oxidative stress via Hog1p; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1746838 1749949 + orf19.5071 1746838 1749949 1 1746838 1749949 1747314 1749605 NRP1 orf19.12537|IPF18762.2|IPF10092.2|Contig4-2713_0003|orf6.2429|orf6.6305|CA3900|CaO19.12537|CaO19.5071|IPF10092 Predicted ORF in Assemblies 19, 20 and 21; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1750143 1751122 + orf19.5073 1750143 1751122 1 1750143 1751122 1750300 1751019 DPM1 orf19.12539|IPF22152.1|IPF10089.2|Contig4-2713_0004|orf6.6303|CA3899|DPMS|CaO19.12539|CaO19.5073 Protein with similarity to S. cerevisiae Dpm1p, which is dolichol phosphate mannose synthase; filament induced; Tup1p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1751283 1753286 + orf19.5074 1751283 1753286 1 1751283 1753286 1751322 1753196 orf19.12540|IPF22128.1|IPF10088.2|Contig4-1814_0001|Contig4-2713_0005|orf6.6302|CA3898|CaO19.5074|UBA2|CaO19.12540 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1753572 1754201 + orf19.5076 1753572 1754201 1 1753572 1754201 1753657 1754037 PFY1 orf19.12542|orf6.6300|IPF22172.1|IPF16724.2|Contig4-1814_0003|CA3897|CaO19.5076|CaO19.12542 Profilin, functional homolog of S. cerevisiae Pfy1p; hyphal-induced; macrophage/pseudohyphal-induced; regulated by Nrg1p, Tup1p; gene lacks intron (unlike S. cerevisiae PFY1); complements growth of S. cerevisiae srv2 mutant; nonessential [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1754137 1754446 - ntar_167 1754137 1754446 1 1754446 1754137 1754446 1754273 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1754493 1755250 + orf19.5076.1 1754493 1755250 1 1754493 1755250 1754779 1755012 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1754642 1755046 - ntar_168 1754642 1755046 1 1755046 1754642 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1755444 1756220 + orf19.5077 1755444 1756220 1 1755444 1756220 1755501 1756001 orf19.12543|IPF22157.1|IPF10339.2|Contig4-1814_0007|orf6.6299|CA3896|CaO19.12543|CaO19.5077|IPF10339 Predicted ORF in Assemblies 19, 20 and 21; repressed by nitric oxide; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1756169 1757480 - ntar_169 1756169 1757480 1 1757480 1756169 1756822 1756694 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1756528 1757212 + orf19.5078 1756528 1757212 1 1756528 1757212 1756580 1756987 orf19.12544|IPF22175.1|IPF10341.1|orf6.6298|CaO19.5078|CaO19.12544 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1757938 1762669 + orf19.5079 1757938 1762669 1 1757938 1762669 1758073 1762545 CDR4 orf19.12545|IPF22170.1|IPF10349.2|orf6.6297|CA3895|CaO19.12545|CaO19.5079 Putative transporter of ATP-binding cassette (ABC) superfamily; fluconazole, Sfu1p, Hog1p, core stress response induced; caspofungin repressed; fluconazole resistance is not affected by mutation or correlated with expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1762642 1763481 - orf19.5079.1 1762642 1763481 1 1763481 1762642 1763442 1763056 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1763645 1766898 - orf19.5081 1763645 1766898 1 1766898 1763645 1766850 1763797 FUN12 orf19.12547|IPF22183.1|IPF8722.1|Contig4-2712_0006|orf6.6295|CA3894|CaO19.12547|CaO19.5081|YIF2 Functional homolog of S. cerevisiae Fun12p translation initiation factor eIF5B; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1767343 1768664 + orf19.5083 1767343 1768664 1 1767343 1768664 1767426 1768532 DRG1 orf19.12549|IPF22140.1|IPF8715.2|Contig4-2712_0003|orf6.6293|CA3893|FUN11|CaO19.12549|CaO19.5083 Member of the DRG family of GTP-binding proteins; involved in regulation of invasive filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1768800 1772408 + orf19.5085 1768800 1772408 1 1768800 1772408 1769083 1772358 orf19.12551|IPF22181.1|IPF8712.2|Contig4-2712_0001|orf6.6291|CA3892|PSE1|CaO19.12551|CaO19.5085 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1772677 1775122 + orf19.5087 1772677 1775122 1 1772677 1775122 1772735 1774846 BUD6 orf19.12553|IPF22122.1|IPF8707.2|Contig4-2085_0001|orf6.6289|CA3891|CaO19.5087|CaO19.12553 Protein required for Spitzenkorper formation in hyphal cells (wild-type localization of Mlc1p to the Spitzenkorper); localizes to polarisome [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1774798 1777461 - orf19.5089 1774798 1777461 1 1777461 1774798 1777459 1774856 TERT orf19.12555|orf6.6287|TERT1|TERT2|IPF22114.1|IPF19791.1|Contig4-2085_0003|CA3890|EST2|CaO19.12555|TRT1|CaO19.5089 Telomerase reverse transcriptase; catalytic protein subunit of telomere synthesis; essential for telomerase activity; has telomerase-specific motif T and other conserved reverse transcriptase motifs [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1777612 1778726 + orf19.5090 1777612 1778726 1 1777612 1778726 1777650 1778630 orf19.12556|IPF22143.1|IPF12969.2|Contig4-2641_0017|orf6.6286|CA3889|TAD3|CaO19.12556|CaO19.5090 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1778151 1779265 - orf19.5092 1778151 1779265 1 1779265 1778151 1779265 1778627 orf19.12558|IPF22155.1|IPF12967.1|Contig4-2641_0001|orf6.6284|CA3888|CaO19.12558|CaO19.5092|IPF12967 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 1779290 1780639 + orf19.5093 1779290 1780639 1 1779290 1780639 1779375 1780433 orf19.12559|IPF22141.1|IPF12964.2|Contig4-2641_0003|orf6.6283|CA3887|SFH1|CaO19.5093|CaO19.12559|IPF12964 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1780557 1783057 - orf19.5094 1780557 1783057 1 1783057 1780557 1782963 1780738 BUL1 orf19.12560|IPF22119.1|IPF12963.2|Contig4-2641_0004|Contig4-2641_0005|orf6.6282|CA3886|BUL5|CaO19.12560|CaO19.5094|IPF12963 Protein not essential for viability; macrophage/pseudohyphal-induced; similar to S. cerevisiae Bul1p, which may be involved in selection of substrates for ubiquitination [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1784600 1784868 + ntar_170 1784600 1784868 1 1784600 1784868 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1785343 1789537 - orf19.5095 1785343 1789537 1 1789537 1785343 1789380 1785424 orf19.12561|IPF22177.1|IPF19790.1|Contig4-2641_0013|Contig4-2641_0015|orf6.4030|orf6.6281|CA3885|OSH2|CaO19.5095|IPF19790 Predicted ORF in Assemblies 19, 20 and 21; caspofungin induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1790346 1793765 - orf19.5097 1790346 1793765 1 1793765 1790346 1793606 1790436 CAT8 orf19.12563|IPF9674.2|IPF28167.1|Contig4-2662_0002|Contig4-2662_0003|orf6.4032|CaO19.5097|CaO19.12563|CA2219 Predicted zinc-cluster protein; null mutant shows a defect in transcription of JEN1 lactate permease gene; flucytosine repressed; similar to S. cerevisiae Cat8p but mutant phenotype suggests that it has a different set of target genes [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1794185 1795270 + orf19.5098 1794185 1795270 1 1794185 1795270 1794223 1795185 NTG1 orf19.12564|orf6.4033|IPF22144.1|IPF9671.1|Contig4-2662_0007|CA2220|CaO19.12564|CaO19.5098 Protein with strong similarity to both S. cerevisiae Ntg1p and Ntg2p DNA repair glycosylases; transcriptionally regulated by iron; expression greater in high iron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1795243 1800188 - orf19.5100 1795243 1800188 1 1800188 1795243 1800113 1795293 MLT1 orf19.12566|ABC1|BPT1|YCF1|BPT1-2|IPF22163.1|IPF9670.2|Contig4-2662_0008|Contig4-2662_0011|Contig4-2662_0013|orf6.4035|CA2221|CaO19.12566|CaO19.5100|IPF9670 Vacuolar membrane transporter: MRP subfamily of ABC family; similar to S. cerevisiae Bpt1p and Ycf1p; may transport organic anions conjugated to glutathione, glucuronate, or sulfate; required for virulence in mouse peritonitis model [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1800842 1801282 + ntar_171 1800842 1801282 1 1800842 1801282 1801098 1801232 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1801471 1804140 + orf19.5101 1801471 1804140 1 1801471 1804140 1801719 1804082 CCR4 orf19.12567|IPF22115.1|IPF13962.2|Contig4-2297_0004|orf6.4036|CA2222|CaO19.12567|CaO19.5101 Protein similar to S. cerevisiae Ccr4p of the CCR4-NOT transcription regulatory complex; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1804132 1806475 - orf19.5102 1804132 1806475 1 1806475 1804132 1806443 1804179 PLB5 orf19.12568|IPF13965.2|IPF17127.3|Contig4-2297_0003|orf6.4037|orf6.6348|CA2223|CaO19.5102 Putative phospholipase B, fungal-specific (no human or murine homolog); null mutation eliminates cell-associated phospholipase A2 activity and attenuates virulence; putative GPI anchor [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1806853 1808045 - orf19.5103 1806853 1808045 1 1808045 1806853 1807929 1806937 orf19.12569|IPF17128.2|IPF12719.2|Contig4-1667_0001|orf6.4038|orf6.6347|CA3931|PMU5|CaO19.5103|IPF12719 Predicted ORF in Assemblies 19, 20 and 21; clade-associated gene expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1808962 1809773 - orf19.5104 1808962 1809773 2 1809773|1809464 1809627|1808962 1809691 1809023 LTP1 orf19.12570|IPF22169.1|IPF12722.1|Contig4-2155_0001|orf6.6346|CA3929|orf19.5104.1|LPT1|CA3930|LPT1.exon2 Putative protein phosphatase of the PTP family (tyrosine-specific), similar to S. cerevisiae Ltp1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1809983 1813984 - orf19.5105 1809983 1813984 1 1813984 1809983 1813627 1810187 orf19.12571|IPF22178.1|IPF12729.2|Contig4-2155_0005|Contig4-2155_0006|orf6.6345|CA3928|CaO19.5105|Gal11|CaO19.12571 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1814478 1814625 + ntar_172 1814478 1814625 1 1814478 1814625 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1816240 1819386 - orf19.5106 1816240 1819386 1 1819386 1816240 1819339 1816394 DIP2 orf19.12572|IPF22110.1|IPF14262.2|Contig4-2615_0005|Contig4-2615_0006|orf6.6344|CA3927|CaO19.12572|CaO19.5106 Protein similar to S. cerevisiae Dip2p, of small ribonucleoprotein complex; transposon mutation affects filamentous growth; physically interacts with TAP-tagged Nop1p; heterozygous null mutant exhibits resistance to parnafungin [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1820188 1822491 + orf19.5107 1820188 1822491 1 1820188 1822491 1820259 1822247 NOT5 orf19.12573|orf6.6343|IPF13254.2|IPF16198.2|Contig4-2615_0003|orf6.142|CA3926|CaO19.12573|CaO19.5107|IPF16198 Protein with similarity to S. cerevisiae Not5p, which is a member of the transcription regulatory CCR4-NOT complex; required for hyphal growth; antigenic during human oral infection; greater expression in yeast-form cells than hyphae [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1823480 1825620 + orf19.5110 1823480 1825620 1 1823480 1825620 1823851 1825434 OPY2 orf19.12576|IPF22134.1|IPF13257.2|Contig4-2451_0005|orf6.6340|CA3925|CaO19.5110|CaO19.12576|IPF13257 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1825876 1828762 + orf19.5112 1825876 1828762 1 1825876 1828762 1826680 1828713 TKL1 orf19.12578|TKT1|IPF22123.1|IPF13260.2|Contig4-2451_0003|orf6.6338|CA3924|CaO19.12578|CaO19.5112 Putative transketolase; localizes to surface of yeast-form cells, but not hyphae; soluble protein in hyphae; transcription is regulated by Nrg1p, Mig1p, and Tup1p; antigenic in human or murine infection [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1829076 1830430 - orf19.5113 1829076 1830430 1 1830430 1829076 1830334 1829288 ADH2 orf19.12579|IPF22142.1|IPF16784.2|Contig4-2451_0001|orf6.6337|CA3923|CaO19.5113 Putative alcohol dehydrogenase; soluble protein in hyphae; fungal-specific (no human or murine homolog); expression is regulated upon white-opaque switching; regulated by Ssn6p; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1831645 1832566 - orf19.5114 1831645 1832566 1 1832566 1831645 1832442 1831969 orf19.12580|IPF22160.1|IPF6349.2|Contig4-3000_0003|orf6.6336|CA3922|CaO19.12580|GRD19|CaO19.5114 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1832750 1833503 - orf19.5114.1 1832750 1833503 1 1833503 1832750 1833139 1832948 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1834155 1835964 - orf19.5117 1834155 1835964 1 1835964 1834155 1835814 1834354 OLE1 orf19.12583|orf6.6333|IPF22136.1|IPF6353.2|Contig4-3000_0008|CA3921|CaO19.5117|CaO19.12583 Fatty acid desaturase (stearoyl-CoA desaturase), essential protein involved in oleic acid synthesis; required for aerobic hyphal growth and chlamydospore formation; subject to hypoxic regulation; fluconazole-induced; caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1838982 1841296 + orf19.5118 1838982 1841296 1 1838982 1841296 1839339 1841225 SDS24 orf19.12584|orf6.6332|IPF22127.1|IPF6359.2|Contig4-3000_0016|Contig4-3000_0017|CA3920|SDS23|CaO19.12584|CaO19.5118 Protein described as similar to S. cerevisiae Ybr214wp; transcription regulated by Mig1p and Tup1p; fluconazole-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1841963 1842100 + ntar_173 1841963 1842100 1 1841963 1842100 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1842478 1844188 + orf19.382 1842478 1844188 1 1842478 1844188 1842606 1843982 TEF2 orf19.8012|IPF26916.1|IPF6365.2|Contig4-3000_0020|orf6.339|TEF2-1|CaO19.382|CaO19.8012 Translation elongation factor 1-alpha; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 1844067 1846082 - orf19.384 1844067 1846082 1 1846082 1844067 1845892 1844216 orf19.8014|IPF6367.2|IPF19375.2|Contig4-2976_0005|orf6.247|orf6.341|orf6.6280|CA3884|CaO19.384|IPF6367 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1846424 1849566 - orf19.385 1846424 1849566 1 1849566 1846424 1849496 1846497 GCV2 orf19.8015|IPF19789.1|IPF6369.3|orf6.246|orf6.6279|CA3883|CaO19.385 Putative protein of glycine catabolism; downregulated by Efg1p; Hog1p-induced; upregulated by Rim101p at acid pH; transcription is activated in the presence of elevated CO2; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1850262 1851563 - orf19.386 1850262 1851563 1 1851563 1850262 1851405 1850470 SAM4 orf19.8016|IPF26919.1|IPF7279.1|Contig4-1631_0002|orf6.6278|CA3882|CaO19.8016|CaO19.386|IPF7279 Alkaline upregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1851756 1854660 + orf19.387 1851756 1854660 1 1851756 1854660 1851872 1854532 GCR3 orf19.8017|IPF26905.1|IPF7281.2|Contig4-3031_0024|orf6.6277|CA3881|CaO19.8017|CaO19.387 Functional homolog of S. cerevisiae Gcr3p, which acts in regulation of glycolytic genes; no intron predicted, in contrast to intron in S. cerevisiae GCR3 gene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1854812 1855966 + orf19.388 1854812 1855966 1 1854812 1855966 1854922 1855884 CAF16 orf19.8018|IPF26920.1|IPF7283.2|Contig4-3031_0023|orf6.6276|CaO19.8018|CaO19.388|CA3880 ABC family protein, predicted not to be a transporter; caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1855791 1856439 - orf19.389 1855791 1856439 1 1856439 1855791 1856347 1855967 orf19.8019|IPF26932.1|IPF7284.2|Contig4-3031_0022|orf6.6275|CaO19.389|CaO19.8019 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1856685 1857765 - orf19.390 1856685 1857765 1 1857765 1856685 1857461 1856886 CDC42 orf19.8020|IPF26926.1|IPF7286.2|Contig4-3031_0021|orf6.6274|CA3879|CaO19.8020|CaO19.390 Rho-type GTPase; required for budding and maintenance of hyphal growth; GGTase I geranylgeranylated; misexpression blocks hyphal growth, causes avirulence in mouse IV infection; shows actin-dependent localization to hyphal tip [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1858202 1860914 - orf19.391 1858202 1860914 1 1860914 1858202 1860375 1858237 UPC2 orf19.8021|IPF26909.1|IPF7289.2|Contig4-3031_0016|Contig4-3031_0018|orf6.6273|CA3878|CaO19.8021|ECM22|CaO19.391|IPF7289 Transcriptional regulator of ergosterol biosynthetic genes and sterol uptake; binds ERG2 promoter; has Zn(2)-Cys(6) binuclear cluster; induced upon ergosterol depletion, by azoles, anaerobicity; macrophage/pseudohyphal-repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1858273 1858554 + ntar_174 1858273 1858554 1 1858273 1858554 1858391 1858546 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1861178 1861910 + orf19.392 1861178 1861910 1 1861178 1861910 1861319 1861753 orf19.8022|IPF26931.1|IPF7290.1|Contig4-3031_0013|orf6.6272|CA3877|CBP4|CaO19.392|CaO19.8022 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1861670 1862464 - orf19.393 1861670 1862464 2 1862464|1862324 1862393|1861670 1862414 1861819 orf19.8023|IPF7291.2|IPF29846.1|Contig4-3031_0012|orf6.6271|CA3876|APS3|CaO19.393 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1862562 1864117 + orf19.394 1862562 1864117 1 1862562 1864117 1862609 1863994 orf19.8024|IPF14430.2|IPF29842.1|Contig4-3031_0011|orf6.6270|CA3875|CaO19.394|IPF14430 Putative kynureninase, involved in NAD biosynthesis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1864133 1865606 - orf19.395 1864133 1865606 1 1865606 1864133 1865548 1864226 ENO1 orf19.8025|IPF26917.1|IPF14429.2|Contig4-3031_0010|orf6.6269|CA3874|ENO|CaO19.395|CaO19.8025 Enolase (2-phospho-D-glycerate-hydrolyase), enzyme of glycolysis and gluconeogenesis; major cell-surface antigen; binds host plasmin and plasminogen; immunoprotective; phagocytosis, biofilm-regulated; farnesol-downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1866384 1867304 + orf19.396 1866384 1867304 1 1866384 1867304 1866510 1867145 EAF6 orf19.8026|IPF26924.1|IPF8825.1|Contig4-2296_0007|Contig4-3031_0009|orf6.6268|CA3873|CaO19.8026|CaO19.396|IPF8825 Subunit of the NuA4 histone acetyltransferase complex [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1867082 1867693 - orf19.397 1867082 1867693 1 1867693 1867082 1867667 1867224 orf19.8027|IPF26928.1|IPF8826.2|Contig4-3031_0008|orf6.6267|CA3872|MRPL28|CaO19.397|CaO19.8027 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1867848 1868511 + orf19.398 1867848 1868511 1 1867848 1868511 1867938 1868411 orf19.8028|IPF26929.1|IPF8828.2|Contig4-3031_0007|orf6.6266|CA3871|CaO19.8028|CaO19.398|IPF8828 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1868490 1870780 - orf19.399 1868490 1870780 1 1870780 1868490 1870656 1868518 orf19.8029|IPF26907.1|IPF8830.2|Contig4-3031_0005|orf6.6265|CA3870|CaO19.399|YPK2|CaO19.8029|YPK1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1871191 1872370 - orf19.400 1871191 1872370 1 1872370 1871191 1872201 1871464 GCF1 orf19.8030|IPF26922.1|IPF8831.2|Contig4-3031_0004|orf6.6264|CA3869|CaO19.400|CaO19.8030|IPF8831 HMG box-containing mitochondrial (mt) protein; binds to mt DNA and to the HWP1 promoter; mutant phenotype and functional complementation of an S. cerevisiae abf2 mutation suggest a role in mt genome replication and maintenance [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1872886 1874949 + orf19.401 1872886 1874949 1 1872886 1874949 1872960 1874624 TCP1 orf19.8031|CCT1|IPF26911.1|IPF8832.2|Contig4-3031_0002|orf6.6263|CA3868|CaO19.401|CaO19.8031 Transcription is induced in response to alpha pheromone in SpiderM medium; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1874853 1875711 - orf19.403 1874853 1875711 1 1875711 1874853 1875646 1874882 PCL2 orf19.8033|IPF26921.1|IPF8834.3|Contig4-3031_0001|orf6.2813|orf6.6261|CA1351|CaO19.403|IPF8834.2 Cyclin homolog; reduced expression observed upon depletion of Cln3p; farnesol regulated; periodic mRNA expression, peak at cell-cycle G1/S phase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1877268 1877957 + ntar_175 1877268 1877957 1 1877268 1877957 1877457 1877642 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1877892 1879482 - orf19.405 1877892 1879482 1 1879482 1877892 1879275 1878025 VCX1 orf19.8035|IPF26918.1|IPF16576.2|Contig4-2020_0006|orf6.2815|CA1352|CaO19.8035|CaO19.405 Putative H+/Ca2+ antiporter; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1880541 1882337 - orf19.406 1880541 1882337 1 1882337 1880541 1882136 1880646 ERG1 orf19.8036|IPF26914.1|IPF19729.1|Contig4-2020_0009|Contig4-2020_0010|orf6.2816|CA1353|CaO19.8036|CaO19.406 Squalene epoxidase, catalyzes epoxidation of squalene to 2,3(S)-oxidosqualene in the ergosterol biosynthetic pathway; essential; target of allylamine antifungal drugs; uses NADH as a reducing cofactor, while S. cerevisiae Erg1p uses NADPH [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1882594 1882743 + ntar_176 1882594 1882743 1 1882594 1882743 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1882784 1885099 - orf19.407 1882784 1885099 1 1885099 1882784 1885055 1882857 GCD6 orf19.8037|IPF26908.1|IPF10142.2|Contig4-2780_0002|orf6.2817|CA1354|CaO19.8037|CaO19.407 Putative catalytic epsilon subunit of the translation initiation factor eIF2B, based on similarity to S. cerevisiae Gcd6p; genes encoding translation factors are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1885178 1885588 + ntar_177 1885178 1885588 1 1885178 1885588 1885312 1885494 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1885487 1886398 - orf19.409 1885487 1886398 1 1886398 1885487 1886244 1885603 orf19.8039|IPF10138|IPF26923.1|IPF10138.2|Contig4-2780_0005|orf6.2819|CA1356|CaO19.8039|CaO19.409|IPF10138.5f Predicted membrane protein; similar to S. cerevisiae Ynr018Wp [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1886569 1887623 + orf19.4720 1886569 1887623 1 1886569 1887623 1886980 1887468 CTR2 orf19.12183|IPF22485.1|IPF15729.2|Contig4-2780_0006|orf6.3182|CA1600|orf19.72|CaO19.12183|CaO19.4720 Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide; clade-associated gene expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1887718 1889347 + orf19.4721 1887718 1889347 1 1887718 1889347 1887838 1889175 orf19.12184|IPF22424.1|IPF15728.2|Contig4-2780_0007|orf6.3183|CA1601|CaO19.12184|CaO19.4721|IPF15728 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1889408 1890580 + orf19.4722 1889408 1890580 1 1889408 1890580 1889579 1890403 orf19.12185|IPF18649.2|IPF13658.2|Contig4-2780_0008|orf6.3184|CA1602|CaO19.4722|RTG1|CaO19.12185 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1890402 1891555 - orf19.4723 1890402 1891555 2 1891555|1891207 1891293|1890402 1891525 1890589 orf19.12186|IPF22475.1|IPF22533.1|IPF13656.2|IPF13655.2|Contig4-2780_0009|orf6.3185|CA1603|FAD1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1891689 1892585 - orf19.4724 1891689 1892585 1 1892585 1891689 1892559 1891789 orf19.12187|IPF22466.1|IPF13653.2|Contig4-2780_0010|orf6.3186|CA1604|CaO19.4724|SAP62|CaO19.12187|IPF13653 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1892816 1895340 + orf19.4725 1892816 1895340 1 1892816 1895340 1893017 1895206 SWI6 orf19.12188|IPF22383.1|IPF17885.2|orf6.3187|CA1605|CaO19.12188|CaO19.4725 Predicted ORF in Assemblies 19, 20 and 21; periodic mRNA expression, peak at cell-cycle G1/S phase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1895254 1896022 - orf19.4726 1895254 1896022 1 1896022 1895254 1895937 1895362 orf19.12189|IPF22479.1|IPF16484.1|orf6.3188|CA1606|FRQ1|CaO19.4726|CaO19.12189|NCS1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1896169 1896877 + orf19.4727 1896169 1896877 1 1896169 1896877 1896273 1896740 orf19.12190|IPF14916.2|IPF16483.1|orf6.2181|orf6.3189|CA1607|CaO19.4727|IPF14916 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1897055 1901385 + orf19.4728 1897055 1901385 1 1897055 1901385 1897223 1901365 orf19.12191|IPF14914.2|IPF18648.2|IPF16481.2|orf6.2182|orf6.3190|orf6.439|CA0956|CA6289|orf19.4729|IPF14914.5f|IPF14914 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1901564 1902491 + orf19.4730 1901564 1902491 2 1901564|1901655 1901592|1902491 1901579 1902363 orf19.12192|IPF22474.1|IPF14323.2|orf6.2183|orf6.438|CA0079|CaO19.4730|IPF14323 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1902948 1904358 + orf19.4731 1902948 1904358 1 1902948 1904358 1903070 1904245 orf19.12193|IPF14322.1|IPF19274.1|Contig4-2484_0005|orf6.2184|orf6.437|CA0957|COG5|CaO19.4731|IPF14322 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1904252 1907259 - orf19.4732 1904252 1907259 1 1907259 1904252 1907202 1904416 SEC24 orf19.12194|IPF14321.2|IPF11772.2|Contig4-2484_0008|orf6.2083|orf6.2185|CA0958|CaO19.4732 Possible role in ER to Golgi transport; induced upon yeast-hyphal switch [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1907506 1908553 + orf19.4733 1907506 1908553 1 1907506 1908553 1907576 1908484 YMC2 orf19.12195|IPF22458.1|IPF11767.2|Contig4-2643_0001|orf6.2084|orf6.2186|CA0889|CaO19.4733|IPF11767 Predicted ORF in Assemblies 19, 20 and 21; Gcn4p-regulated; induced upon biofilm formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1908483 1908750 - ntar_178 1908483 1908750 1 1908750 1908483 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1908893 1910052 + orf19.4734 1908893 1910052 1 1908893 1910052 1908930 1909979 orf19.12196|IPF18826.1|IPF11766.1|Contig4-2643_0004|orf6.2085|orf6.2187|CA0890|CaO19.4734|IPF11766 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1910136 1911529 + orf19.4735 1910136 1911529 1 1910136 1911529 1910244 1911296 orf19.12197|IPF22444.1|IPF11764.2|Contig4-2643_0006|orf6.2086|CA0891|CaO19.12197|CaO19.4735|IPF11764 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1911435 1911781 - ntar_179 1911435 1911781 1 1911781 1911435 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1911988 1913993 + orf19.4736 1911988 1913993 1 1911988 1913993 1912123 1913778 orf19.12198|IPF22412.1|IPF19888.1|Contig4-2643_0008|Contig4-2643_0009|orf6.2087|CA0892|CaO19.4736|CaO19.12198|PHO8.5 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1914685 1916784 + orf19.4737 1914685 1916784 1 1914685 1916784 1914936 1916693 TPO3 orf19.12199|orf6.3649|YPR156|YGR138|DHA12|IPF11759.2|IPF10646.3|Contig4-2892_0021|orf6.2088|CA1943|IPF11759|CaO19.4737|IPF11759.3f Possible role in polyamine transport; MFS-MDR family; transcription induced by Sfu1p, regulated upon white-opaque switching; decreased expression in hyphae compared to yeast-form cells; regulated by Nrg1p; fungal-specific [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1916993 1918889 + orf19.4738 1916993 1918889 1 1916993 1918889 1917067 1918743 orf19.12200|IPF22411.1|IPF10645.2|Contig4-2892_0001|orf6.3650|CA1944|CaO19.4738|CaO19.12200|IPF10645 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1918849 1921025 - orf19.4739 1918849 1921025 1 1921025 1918849 1920976 1918970 MSS116 orf19.12201|IPF22389.1|IPF10643.2|Contig4-2892_0003|orf6.3651|CA1945|CaO19.4739|CaO19.12201 Predicted ORF in Assemblies 19, 20 and 21; transcription is upregulated in both intermediate and mature biofilms [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1921097 1921864 - orf19.4740 1921097 1921864 1 1921864 1921097 1921826 1921194 orf19.12202|IPF22476.1|IPF19937.1|Contig4-2447_0002|Contig4-2447_0003|orf6.3652|CA1946|CaO19.12202|CaO19.4740|IPF19937 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1921198 1921522 + ntar_180 1921198 1921522 1 1921198 1921522 1921198 1921335 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1921949 1924126 + orf19.4742 1921949 1924126 1 1921949 1924126 1922856 1923920 orf19.12204|IPF10637.1|IPF19297.2|Contig4-2037_0002|orf6.3654|orf6.403|CA1947|CaO19.4742|IPF10637 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 1922090 1922673 - orf19.4741 1922090 1922673 3 1922673|1922341|1922216 1922413|1922283|1922090 1922673 1922090 orf19.12203|IPF10638.2|IPF28263.1|Contig4-2037_0001|orf6.3653|CaO19.4741|CaO19.12203 Predicted ORF in Assemblies 19, 20 and 21; possibly C. albicans-specific [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 1924028 1926210 - orf19.4743 1924028 1926210 1 1926210 1924028 1926159 1924093 AFG1 orf19.12205|IPF14022.2|IPF10636.3|Contig4-2037_0003|orf6.3655|orf6.404|CA1948|CaO19.4743|AFG12|IPF14022 Protein not essential for viability; similar to S. cerevisiae Afg1p, which is a putative mitochondrial ATPase of the AAA family [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1926297 1928953 - orf19.4744 1926297 1928953 1 1928953 1926297 1928615 1926408 orf19.12206|IPF14021.2|IPF18510.2|orf6.3656|orf6.4015|CA1949|CaO19.4744|IPF14021 Predicted ORF in Assemblies 19, 20 and 21; transcription is repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1928959 1930837 - orf19.4746 1928959 1930837 1 1930837 1928959 1930727 1929099 JIP5 orf19.12208|IPF14019|IPF14019.1|IPF13928.2|orf6.3658|orf6.4016|CA1950|CaO19.4746 Protein not essential for viability; downregulated during core stress response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1931275 1933015 + orf19.4747 1931275 1933015 1 1931275 1933015 1931411 1933006 HEM14 orf19.12209|orf6.4017|orf6.3659|IPF19663.1|IPF19662.1|CA1951|CaO19.4747 Putative protoporphyrinogen oxidase involved in heme biosynthesis; predicted Kex2p substrate; transcription is regulated by iron; mRNA levels are decreased in a yfh1 null mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1932154 1933539 - orf19.4748 1932154 1933539 1 1933539 1932154 1933452 1933057 orf19.12210|IPF18582.2|IPF13925.1|Contig4-2151_0009|orf6.3660|orf6.4018|CA2210|MSL1|CaO19.4748|U2B'' Putative U2B'' component of the U2 snRNP, involved in splicing; contains an RNA recognition motif (RRM); ortholog of S. cerevisiae MSL1; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1933778 1935640 + orf19.4749 1933778 1935640 1 1933778 1935640 1933898 1935574 orf19.12211|IPF22427.1|IPF13921.2|Contig4-2151_0005|Contig4-2151_0007|Contig4-2151_0008|orf6.4019|CA2211|CaO19.4749|IPF13921 Predicted ORF in Assemblies 19, 20 and 21; hyphal-induced expression, regulated by Cyr1p, Ras1p, Efg1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1936163 1938444 - orf19.4750 1936163 1938444 1 1938444 1936163 1938354 1936252 orf19.12212|IPF16404.3|IPF13919.2|Contig4-2151_0001|orf6.4020|orf6.88|CA2212|CaO19.4750|IPF13919 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 1938535 1939578 + orf19.4751 1938535 1939578 1 1938535 1939578 1938588 1939475 orf19.12214|IPF22488.1|IPF16405.2|Contig4-1898_0001|orf6.4021|orf6.89|CA2213|RSM25|CaO19.4751|IPF16405 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1939437 1940022 - orf19.4751.1 1939437 1940022 1 1940022 1939437 1939877 1939653 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1940231 1943194 - orf19.4752 1940231 1943194 1 1943194 1940231 1942792 1940516 MSN4 orf19.12215|IPF22377.1|IPF9939.2|Contig4-1898_0007|Contig4-2609_0002|orf6.4022|CA2214|CaO19.12215|CaO19.4752|IPF9939 Putative zinc finger transcription factor; similar to S. cerevisiae Msn4p, but not a significant stress response regulator in C. albicans; partly complements STRE-activation defect of S. cerevisiae msn2 msn4 double mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1947493 1951816 + orf19.4753 1947493 1951816 1 1947493 1951816 1948259 1951699 PFK26 orf19.12217|IPF17562.3|IPF9943.2|Contig4-1843_0004|orf6.1050|orf6.4023|CA2215|CaO19.4753 Protein repressed during the mating process [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1947497 1947873 - ntar_181 1947497 1947873 1 1947873 1947497 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1952161 1953340 + ntar_182 1952161 1953340 1 1952161 1953340 1952510 1952635 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1953280 1955035 - orf19.4754 1953280 1955035 1 1955035 1953280 1954892 1953369 ZWF1 orf19.12218|IPF13060.2|IPF18011.3|Contig4-2455_0008|orf6.4024|orf6.4601|CA2634|CaO19.4754 Putative glucose-6-phosphate dehydrogenase; antigenic in murine infection; activity induced by O2 or oxidizing agents H2O2 or menadione; caspofungin repressed; macrophage induced; induced in core stress response; regulated by Gcn2p, Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1955571 1956026 - ntar_183 1955571 1956026 1 1956026 1955571 1955885 1955718 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1955730 1956207 + ntar_184 1955730 1956207 1 1955730 1956207 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1956359 1959551 - orf19.4755 1956359 1959551 1 1959551 1956359 1959364 1956554 KEX2 orf19.12219|IPF22355.1|IPF13063.2|Contig4-2455_0002|orf6.4600|CA2633|CaO19.12219|CaO19.4755 Subtilisin-like protease (proprotein convertase), processes aspartyl proteinase Sap2p; required for hyphal growth and wild-type virulence in mouse systemic infection; functional homolog of S. cerevisiae Kex2p, which processes alpha-factor [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1959935 1960147 - ntar_185 1959935 1960147 1 1960147 1959935 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1960367 1962187 + orf19.4756 1960367 1962187 1 1960367 1962187 1960409 1962061 orf19.12220|IPF22404.1|IPF19763.1|Contig4-2725_0001|orf6.4599|CA6214|YTP1|CaO19.4756|CaO19.12220 Predicted ORF in Assemblies 19, 20 and 21; fungal-specific [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1962461 1964578 + orf19.4757 1962461 1964578 1 1962461 1964578 1962576 1964405 NAR1 orf19.12221|IPF22395.1|IPF14388.2|Contig4-2557_0009|Contig4-2557_0010|orf6.4598|CA2632|CaO19.12221|CaO19.4757 Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide; oxidative stress-induced via Cap1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1964855 1966007 + orf19.4758 1964855 1966007 1 1964855 1966007 1965098 1965838 orf19.12222|IPF22468.1|IPF14389.2|Contig4-2557_0006|orf6.4597|CA2631|CaO19.4758|CaO19.12222|IPF14389 Predicted ORF in Assemblies 19, 20 and 21; alkaline downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1966084 1967184 - orf19.4759 1966084 1967184 2 1967184|1966919 1967184|1966084 1966889 1966392 COX5 orf19.12223|IPF10910.2|IPF28262.1|COX5A|Contig4-2557_0005|orf6.4596|CA2630|CaO19.12223|CaO19.4759 Protein described as cytochrome oxidase subunit V; has putative regulatory element, upstream CCAAT box; macrophage/pseudohyphal-induced; repressed by nitric oxide; intron in 5'-UTR [label_first_exon=CGD label_last_exon=CGDmod orf_changed=true scenario_first_exon=Z scenario_last_exon=A] Ca21chr1 1967293 1969056 - orf19.4760 1967293 1969056 1 1969056 1967293 1969056 1967593 orf19.12224|IPF18440.1|IPF10911.2|Contig4-2557_0004|orf6.179|orf6.4595|CA2629|CaO19.4760|IPF10911 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 1969649 1972007 + orf19.4761 1969649 1972007 1 1969649 1972007 1969837 1971810 HST1 orf19.12225|IPF10913.2|IPF19405.2|Contig4-2557_0001|orf6.178|orf6.4594|CA2628|CaO19.4761|SIR21|SIR22 Putative histone deacetylase, involved in regulation of white-opaque switching; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1971988 1973581 - orf19.4763 1971988 1973581 1 1973581 1971988 1972938 1972258 orf19.12227|IPF10916|IPF22471.1|IPF10916.2|orf6.4592|CA2627|CaO19.12227|CaO19.4763 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1973677 1977482 + orf19.4764 1973677 1977482 1 1973677 1977482 1973795 1977367 orf19.12228|IPF22512.1|IPF10918.2|Contig4-2669_0005|orf6.4591|CA2626|PAN2|CaO19.4764|CaO19.12228 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 1977435 1979093 - orf19.4765 1977435 1979093 1 1979093 1977435 1978893 1978234 PGA6 orf19.12229|orf6.4590|IPF10919.2|IPF17733.2|Contig4-2442_0006|CA2625|CCW12|CaO19.4765|IPF10919 Putative GPI-anchored cell wall protein of unknown function; transcriptionally induced under high iron conditions; upregulated upon Als2p depletion; mRNA binds to She3p and is localized to hyphal tips [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1980919 1984426 - orf19.4766 1980919 1984426 1 1984426 1980919 1984359 1981057 ARG81|orf19.12230|IPF22523.1|IPF14033.2|Contig4-2442_0003|orf6.2542|CA1175|CaO19.12230|CaO19.4766|CA2624|ARG81.3eoc|IPF17734.2 Putative transcription factor with zinc cluster DNA-binding motif; has similarity to S. cerevisiae Arg81p, which is a transcription factor involved in the regulation of arginine-responsive genes [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 1985142 1985658 - ntar_186 1985142 1985658 1 1985658 1985142 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1985690 1986575 + orf19.4767 1985690 1986575 1 1985690 1986575 1985765 1986505 ZCF28|orf19.12231|IPF22464.1|IPF14255.2|Contig4-2264_0005|orf6.2541|CA1174|CaO19.12231|CaO19.4767|IPF14255 Putative transcription factor with zinc cluster DNA-binding motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1986868 1988598 + orf19.4768 1986868 1988598 1 1986868 1988598 1986872 1988467 orf19.12232|IPF22393.1|IPF14254.2|Contig4-2264_0001|orf6.2540|CA1173|CaO19.12232|CaO19.4768|IPF14254 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 1991221 1993306 + orf19.4769 1991221 1993306 1 1991221 1993306 1991586 1993130 IPT1 orf19.12233|IPF11674.2|IPF17541.2|IPF17540.2|Contig4-2253_0002|orf6.2538|orf6.2539|orf6.927|CA0228|CA6290|orf19.4770|IPT1.5f Inositol phosphoryl transferase, involved in sphingolipid biosynthesis; catalyzes the synthesis of the most abundant sphingolipid, mannose-(inositol-P)2-ceramide, M(IP)2C, from MIPC; required for wild-type membrane localization of Cdr1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 1995811 1996148 - ntar_187 1995811 1996148 1 1996148 1995811 1996148 1996014 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 1996456 1998858 + orf19.4771 1996456 1998858 1 1996456 1998858 1996738 1998858 orf19.12234|IPF22382.1|IPF11667.2|orf6.3982|CA2187|MNN47|CaO19.4771|CaO19.12234|IPF11667 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr1 1999304 2001233 - orf19.4772 1999304 2001233 1 2001233 1999304 2000741 1999578 SSU81 orf19.12235|IPF19613.2|IPF19612.1|Contig4-1937_0004|orf6.3983|orf6.920|SHO1|CA2188|CaO19.4772 Predicted adaptor protein involved in activation of MAP kinase-dependent signaling pathways; links response to oxidative stress to morphogenesis and cell wall biosynthesis; caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2002059 2002295 + ntar_188 2002059 2002295 1 2002059 2002295 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2002432 2002706 + ntar_189 2002432 2002706 1 2002432 2002706 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2003676 2003904 + ntar_190 2003676 2003904 1 2003676 2003904 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2004859 2006146 + orf19.4773 2004859 2006146 1 2004859 2006146 2004893 2005990 AOX2 orf19.12237|AOX1b|IPF19101.2|IPF9420.2|Contig4-2351_0003|orf6.3984|CA2189|AOX2.3f Alternative oxidase; induced by antimycin A, some oxidants; growth- and carbon-source-regulated; one of two isoforms (Aox1p and Aox2p); involved in cyanide-resistant respiratory pathway that is absent from S. cerevisiae [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2006859 2008657 + orf19.4774 2006859 2008657 1 2006859 2008657 2007337 2008476 AOX1 orf6.3985|AOX1a|IPF22441.1|IPF9418.2|Contig4-2351_0001|CA2190|CaO19.4774|CaO19.12237 Alternative oxidase; low abundance; constitutively expressed; one of two isoforms (Aox1p and Aox2p); involved in a cyanide-resistant respiratory pathway present in plants, protists, and some fungi, although absent from S. cerevisiae [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2008450 2009364 - ntar_191 2008450 2009364 1 2009364 2008450 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2009914 2012781 + orf19.4775 2009914 2012781 1 2009914 2012781 2010391 2012676 CTA8 orf19.12238|IPF19046.2|IPF9417.2|Contig4-2247_0002|Contig4-2247_0004|orf6.1107|orf6.3986|CA2191|CaO19.4775|IPF9417|HSF1 Essential transcription factor, mediates heat shock transcriptional induction; in the absence of heat stress, Cta8p levels are modulated by growth temperature to regulate basal expression of genes involved in protein folding [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2014918 2017567 + orf19.4776 2014918 2017567 1 2014918 2017567 2014937 2017567 LYS143|orf19.12240|IPF11774.2|IPF9416.3|Contig4-2888_0010|orf6.1106|orf6.3987|orf6.1105|CA6215|CaO19.4776|IPF9416 Putative transcription factor with zinc cluster DNA-binding motif; has similarity to S. cerevisiae Lys14p, which is a transcription factor involved in the regulation of lysine biosynthesis genes [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chr1 2017546 2019674 - orf19.4777 2017546 2019674 1 2019674 2017546 2019470 2017683 DAK2 orf19.12241|IPF22403.1|IPF11775.3|Contig4-2888_0009|orf6.1104|orf6.1906|CA0776|CaO19.4777|CA0311|DAK2.3eoc|IPF19048.1 Protein described as similar to dihydroxyacetone kinase; transcription is decreased upon yeast-hyphal switch; fluconazole-induced; caspofungin repressed; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2020201 2022557 + orf19.4778 2020201 2022557 1 2020201 2022557 2020314 2022383 LYS142|orf19.12242|IPF22385.1|IPF11777.2|Contig4-2888_0007|orf6.1907|CA0777|CaO19.12242|CaO19.4778|IPF11777 Putative transcription factor with zinc cluster DNA-binding motif; has similarity to S. cerevisiae Lys14p, which is a transcription factor involved in the regulation of lysine biosynthesis genes; fungal-specific [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2022386 2024542 - orf19.4779 2022386 2024542 1 2024542 2022386 2024443 2022581 orf19.12243|orf6.1908|IPF12885.3|IPF12884.2|Contig4-2888_0005|Contig4-2888_0006|orf6.1423|CA0778|CaO19.4779|SGE11|IPF12884 Putative transporter; slightly similar to the Sit1p siderophore transporter; Gcn4p-regulated; fungal-specific (no human or murine homolog); transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2024656 2024956 - ntar_192 2024656 2024956 1 2024956 2024656 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2025217 2025500 - ntar_193 2025217 2025500 1 2025500 2025217 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2025826 2027423 + orf19.4780 2025826 2027423 1 2025826 2027423 2025952 2027325 orf19.12244|IPF12887.2|IPF28255.1|Contig4-2888_0004|orf6.1422|CA0474|CaO19.4780|CaO19.12244|IPF12887 Predicted membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2027208 2028428 - orf19.4781 2027208 2028428 1 2028428 2027208 2028376 2027363 GRP1 orf19.12245|IPF12888.1|IPF15705.2|Contig4-2888_0002|orf6.1421|orf6.4891|CA0473|GRE25|CaO19.4781 Protein similar to dihydroflavonol-4-reductases [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2028608 2030198 - orf19.4783 2028608 2030198 1 2030198 2028608 2030152 2028653 orf19.12247|IPF19867.1|IPF15706.1|Contig4-2888_0001|orf6.4893|orf6.1419|CA2831|CaO19.4783|IPF15706 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2031021 2034797 + orf19.4784 2031021 2034797 1 2031021 2034797 2031132 2034725 CRP1 orf19.12248|CRD1|IPF22517.1|IPF19962.1|orf6.1418|orf6.4894|CA2832|CaO19.4784 Copper transporter of the plasma membrane; P1-type ATPase (CPx type); mediates Cu resistance; similar to proteins of Menkes and Wilson disease; copper-induced; Tbf1p-activated; suppresses Cu sensitivity of S. cerevisiae cup1 null mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2034700 2036008 - orf19.4785 2034700 2036008 1 2036008 2034700 2035953 2034826 PTC1 orf19.12249|IPF22443.1|IPF19963.1|orf6.4895|CA2833|CaO19.12249|CaO19.4785 Putative protein phosphatase of the Type 2C-related family (serine/threonine-specific), similar to S. cerevisiae Ptc1p; mutant shows virulence defect [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2036683 2038629 + orf19.4786 2036683 2038629 1 2036683 2038629 2036879 2038543 FGR43 orf19.12250|IPF22408.1|IPF12093.1|Contig4-2482_0003|orf6.4896|CA2834|CaO19.12250|CaO19.4786|IPF12093 Protein lacking an S. cerevisiae ortholog; transposon mutation affects filamentous growth; transcriptionally activated by Mnl1p under weak acid stress; possible spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2038894 2041319 + orf19.4787 2038894 2041319 1 2038894 2041319 2038995 2041187 orf19.12251|IPF22380.1|IPF12091.2|Contig4-2482_0004|orf6.4897|CA2835|CaO19.12251|CaO19.4787|IPF12091 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2041222 2043954 - orf19.4788 2041222 2043954 1 2043954 2041222 2043918 2041345 ARG5,6 orf19.12252|IPF22364.1|IPF12088.2|orf6.4898|CA2836|CaO19.12252|ARG5|6|CaO19.4788|"ARG5|6" Arginine biosynthetic enzyme activities; in S. cerevisiae, processed into distinct polypeptides with acetylglutamate kinase (Arg6p) activity and acetylglutamate-phosphate reductase (Arg5p) activity; Gcn4p regulated; alkaline downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2044719 2045612 - orf19.4789 2044719 2045612 1 2045612 2044719 2045612 2044719 orf19.12253|IPF22459.1|IPF8340.1|Contig4-2744_0002|orf6.4899|CA2837|CaO19.4789|ALD97|CaO19.12253|IPF8340 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2045125 2045280 + ntar_194 2045125 2045280 1 2045125 2045280 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2045988 2048993 - orf19.4791 2045988 2048993 1 2048993 2045988 2048958 2046028 orf19.12255|IPF22538.1|IPF8339.2|Contig4-2744_0004|orf6.4901|CA2838|CaO19.12255|CaO19.4791|IPF8339 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 2050033 2051926 - orf19.4792 2050033 2051926 1 2051926 2050033 2051811 2050138 orf19.12256|IPF22407.1|IPF8336.2|Contig4-2744_0009|orf6.4902|CA2839|CaO19.4792|IPF8336 Predicted ORF in Assemblies 19, 20 and 21; Plc1p-regulated; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2053289 2054013 + ntar_195 2053289 2054013 1 2053289 2054013 2053478 2053618 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2054978 2055922 + orf19.4793 2054978 2055922 1 2054978 2055922 2055044 2055643 orf19.12257|IPF22480.1|IPF20058.1|Contig4-1497_0003|Contig4-1844_0002|orf6.1469|CA0500|CaO19.4793|CaO19.12257|IPF20058 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2056034 2059614 - orf19.4795 2056034 2059614 1 2059614 2056034 2059614 2056114 orf19.12259|IPF16501.2|IPF16767.2|Contig4-1525_0003|Contig4-1525_0004|Contig4-1844_0004|Contig4-3040_0002|orf6.1471|orf6.3054|CA0501|CaO19.4795|IPF16501 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr1 2060855 2061626 + orf19.4796 2060855 2061626 1 2060855 2061626 2060917 2061447 IPF22527.1|IPF16764.2|Contig4-3040_0004|orf6.3055|CA1516|CaO19.4796|CAF20|IPF16764 Predicted ORF in Assemblies 19, 20 and 21; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2061527 2064963 - orf19.4798 2061527 2064963 1 2064963 2061527 2064662 2061786 orf19.12261|IPF22351.1|IPF11045.2|Contig4-3040_0006|orf6.3057|CA1517|EFR3|CaO19.12261|CaO19.4798|IPF11045 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2065350 2065583 - ntar_196 2065350 2065583 1 2065583 2065350 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2065898 2067809 + orf19.4799 2065898 2067809 1 2065898 2067809 2065935 2067767 orf19.12262|IPF22401.1|IPF11040.2|Contig4-3040_0009|Contig4-3040_0010|orf6.3058|CA1518|CaO19.4799|CEF1|CaO19.12262|IPF11040 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2067950 2070404 + orf19.4800 2067950 2070404 1 2067950 2070404 2067976 2070333 RIM20 orf19.12263|ENX3|IPF22375.1|IPF11037.2|Contig4-3040_0011|orf6.3059|CA1519|CaO19.4800|CaO19.12263 Protein involved in the pH response pathway; binds to the transcription factor Rim101p and may serve as a scaffold to facilitate the C-terminal proteolytic cleavage that activates Rim101p; required for alkaline pH-induced hyphal growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2070510 2072170 + orf19.4801 2070510 2072170 1 2070510 2072170 2070537 2071934 orf19.12264|IPF22429.1|IPF11035.2|Contig4-3040_0012|Contig4-3040_0013|orf6.3060|CA1520|CaO19.12264|MOD5|CaO19.4801|IPF11035 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2072038 2073501 - orf19.4802 2072038 2073501 1 2073501 2072038 2073469 2072195 FTH1 orf19.12265|orf6.3061-1|orf6.3061-2|IPF6122.3|IPF11034.2|Contig4-3040_0016|Contig4-3040_0017|orf6.3061|orf6.5208|CA1521|CaO19.4802 Protein not essential for viability; similar to S. cerevisiae Fth1p (putative high affinity iron transporter for intravacuolar stores of iron); repressed by Sfu1p, amphotericin B, caspofungin; induced by alkaline pH, ciclopirox olamine [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2074984 2075361 + orf19.4803 2074984 2075361 1 2074984 2075361 2074984 2075361 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2075465 2076865 + orf19.4804 2075465 2076865 1 2075465 2076865 2075465 2076865 LIP2 orf19.12267|IPF22428.1|IPF6120.2|Contig4-3040_0021|orf6.5210|CA3068|CaO19.12267|CaO19.4804 Secreted lipase; member of a differentially expressed lipase gene family; expressed in alimentary tract, but not oral tissue, during mouse oral infection; may have a role in nutrition and/or in creating an acidic microenvironment [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2077587 2080423 + orf19.4805 2077587 2080423 1 2077587 2080423 2077715 2080315 orf19.12268|IPF22362.1|IPF6117.2|Contig4-3040_0025|orf6.5211|RSN1|CA3069|CaO19.12268|CaO19.4805|IPF6117 Predicted ORF in Assemblies 19, 20 and 21; fungal-specific (no human or murine homolog); transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2080829 2082137 + orf19.4807 2080829 2082137 1 2080829 2082137 2080938 2081912 orf19.12270|IPF22452.1|IPF6114.2|Contig4-3040_0028|orf6.5213|CA3070|PPA2|CaO19.12270|CaO19.4807 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2082099 2087246 - orf19.4808 2082099 2087246 1 2087246 2082099 2087100 2082172 NUP188 orf19.12271|IPF22490.1|IPF6113.2|Contig4-3040_0030|orf6.5214|CA3071|CaO19.4808|CaO19.12271 Transcription is regulated by Nrg1p and Mig1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2087393 2088861 + orf19.4809 2087393 2088861 1 2087393 2088861 2087469 2088764 ERG12 orf19.12272|IPF22438.1|IPF6109.2|Contig4-2674_0002|orf6.5215|CA3072|CaO19.4809|CaO19.12272 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2088781 2089907 - orf19.4811 2088781 2089907 1 2089907 2088781 2089856 2088870 orf19.12274|IPF22450.1|IPF6108.2|Contig4-2674_0003|orf6.5217|CA3073|CaO19.4811|CaO19.12274|IPF6108 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2089980 2090527 + orf19.4812 2089980 2090527 1 2089980 2090527 2090037 2090444 orf19.12275|IPF22504.1|IPF6106.2|Contig4-2674_0005|orf6.5218|CA3074|CaO19.4812|CaO19.12275|IPF6106 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2090440 2092195 - orf19.4813 2090440 2092195 1 2092195 2090440 2092089 2090497 GUA1 orf19.12276|IPF22419.1|IPF6105.2|Contig4-2674_0006|orf6.5219|CA3075|CaO19.12276|CaO19.4813|IPF6105 Predicted ORF in Assemblies 19, 20 and 21; soluble protein in hyphae; flucytosine induced; macrophage-downregulated protein abundance; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2092733 2093068 + orf19.4814 2092733 2093068 1 2092733 2093068 2092733 2093068 orf19.12277|IPF22495.1|IPF6101.2|Contig4-2674_0008|orf6.5220|CA3076|CaO19.12277|CaO19.4814|IPF6101|IPF6101.3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2093265 2094756 + orf19.4815 2093265 2094756 1 2093265 2094756 2093301 2094701 YTM1 orf19.12278|IPF22434.1|IPF6100.2|Contig4-2674_0010|orf6.5221|CA3077|CaO19.12278|CaO19.4815 Protein similar to S. cerevisiae Ytm1p, which is involved in biogenesis of the large ribosomal subunit; transposon mutation affects filamentous growth; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2094614 2096328 - orf19.4816 2094614 2096328 1 2096328 2094614 2096110 2094761 orf19.12279|IPF22435.1|IPF19970.1|Contig4-2674_0011|Contig4-2674_0012|orf6.5222|CA3078|CaO19.4816|CaO19.12279|IPF19970 Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2096545 2097919 + orf19.4817 2096545 2097919 1 2096545 2097919 2096717 2097637 RAM2 orf19.12280|IPF22454.1|IPF15519.2|Contig4-2100_0001|orf6.5223|CA3079|CaO19.4817|CaO19.12280 Alpha subunit of heterodimeric protein geranylgeranyltransferase type I and farnesyltransferase; a-specific transcription; lovastatin and fluconazole regulated; GGTase I enzyme binds zinc, is Mg-dependent; Cdc42p is GGTase I substrate [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2100762 2102081 - ntar_197 2100762 2102081 1 2102081 2100762 2101358 2101161 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2102365 2104312 + orf19.4818 2102365 2104312 1 2102365 2104312 2102705 2104288 orf19.12281|IPF22477.1|IPF22449.1|IPF14797.2|IPF14799.2|Contig4-2177_0002|Contig4-2177_0004|orf6.2401|CA1082|IPF14797.5f|IPF14797 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2104356 2104712 + orf19.4819 2104356 2104712 1 2104356 2104712 2104356 2104712 orf19.12282|IPF22510.1|IPF28271.1|orf6.2400|CaO19.12282|CaO19.4819 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2105008 2105941 - ntar_198 2105008 2105941 1 2105941 2105008 2105941 2105720 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2107046 2108809 + orf19.4820 2107046 2108809 1 2107046 2108809 2107090 2108712 orf19.12283|IPF22417.1|IPF14710.1|Contig4-2746_0015|Contig4-2746_0017|orf6.2399|CA1080|CaO19.4820|CaO19.12283|IPF14710 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2108870 2110276 - orf19.4821 2108870 2110276 1 2110276 2108870 2110276 2108870 LIP1 orf19.12284|IPF22431.1|IPF14712.2|Contig4-2746_0012|Contig4-2746_0014|orf6.2398|CA1079|CaO19.12284|CaO19.4821 Secreted lipase, member of a lipase gene family whose members are expressed differentially in response to carbon source and during infection; may have a role in nutrition and/or in creating an acidic microenvironment [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2111781 2113178 - orf19.4822 2111781 2113178 1 2113178 2111781 2113178 2111781 LIP10 orf19.12285|IPF22423.1|IPF11790.1|Contig4-2746_0010|orf6.7389|CA4757|CaO19.4822|CaO19.12285 [NOT TRANSCRIBED?] Secreted lipase, member of a lipase gene family whose members are expressed differentially in response to carbon source and during infection; may have a role in nutrition and/or in creating an acidic microenvironment [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2114137 2116063 - orf19.4823 2114137 2116063 1 2116063 2114137 2115617 2114226 LIP6 orf19.12286|IPF22433.1|IPF11788.2|Contig4-2746_0007|orf6.7388|CA4756|CaO19.4823|CaO19.12286 Secreted lipase, member of family of lipase genes expressed differentially in response to carbon source and during infection; may have a role in nutrition and/or in creating an acidic microenvironment; induced on adherence to polystyrene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2117570 2118931 + orf19.4824 2117570 2118931 1 2117570 2118931 2117999 2118817 orf19.12287|IPF22463.1|IPF11480.2|Contig4-3078_0040|orf6.7387|CA4755|CaO19.12287|CaO19.4824|IPF11480 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2118807 2119384 - orf19.4825 2118807 2119384 1 2119384 2118807 2119345 2118881 orf19.12288|IPF22489.1|IPF11479.1|Contig4-3078_0039|orf6.7386|CA4754|CaO19.4825|FMC1|CaO19.12288|IPF11479 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2120369 2121874 + orf19.4826 2120369 2121874 2 2120369|2120688 2120468|2121874 2120442 2121755 IDH1 orf19.12289|IPF22447.1|IPF11475.1|Contig4-3078_0035|orf6.7385|CA4753|IDH1.3 Predicted ORF in Assemblies 19, 20 and 21; soluble protein in hyphae; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2122136 2123675 + orf19.4827 2122136 2123675 1 2122136 2123675 2122303 2123589 ADE12 orf19.12290|IPF22437.1|IPF11474.1|Contig4-3078_0033|orf6.7384|CA4752|CaO19.12290|CaO19.4827 Predicted enzyme of adenine biosynthesis; upregulated in biofilm; decreased expression in hyphae compared to yeast-form cells; not induced during GCN response, in contrast to the S. cerevisiae ortholog, which is induced by Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2123952 2126017 + orf19.4828 2123952 2126017 2 2123952|2124481 2124414|2126017 2124372 2125967 orf19.12291|IPF22426.1|IPF11473.2|Contig4-3078_0031|orf6.7383|CA4751|CaO19.4828|CaO19.12291|IPF11473 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2126385 2128841 + orf19.4829 2126385 2128841 1 2126385 2128841 2126419 2128704 DOA1 orf19.12292|IPF22371.1|IPF4477.2|Contig4-3078_0030|orf6.7382|CA4750|CaO19.12292|CaO19.4829|IPF4477 Protein with WD-repeats and a mellitin-like sequence, similar to S. cerevisiae Doa1p, which is involved in ubiquitin-mediated protein degradation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2128679 2129122 - orf19.4830 2128679 2129122 1 2129122 2128679 2129071 2128739 orf19.12293|IPF22516.1|IPF4478.1|Contig4-3078_0029|orf6.7381|CaO19.4830|CaO19.12293 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2129771 2131460 + orf19.4831 2129771 2131460 1 2129771 2131460 2129818 2131359 orf19.12294|IPF22422.1|IPF4481.1|Contig4-3078_0026|orf6.7380|CA4749|CaO19.12294|CFA1|CaO19.4831|IPF4481 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2132245 2134193 + orf19.4833 2132245 2134193 1 2132245 2134193 2132388 2134043 MLS1 orf19.12296|IPF22415.1|IPF4483.1|Contig4-3078_0024|orf6.7378|CA4748|CaO19.12296|CaO19.4833 Malate synthase; enzyme of the glyoxylate cycle; peroxisomal; no mammalian homolog; transcription is induced upon phagocytosis by macrophage; regulated upon white-opaque switching; biofilm-repressed; strong oxidative stress induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2134295 2134999 + orf19.4834 2134295 2134999 1 2134295 2134999 2134295 2134999 orf19.12297|IPF22473.1|IPF4484.1|Contig4-3078_0022|Contig4-3078_0023|orf6.7377|CA4747|CaO19.12297|CaO19.4834|IPF4484 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2134941 2136662 - orf19.4835 2134941 2136662 1 2136662 2134941 2136601 2135018 orf19.12298|IPF22416.1|IPF4485.1|Contig4-3078_0021|orf6.7376|CA4746|CaO19.4835|CaO19.12298|IPF4485 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2136843 2138458 + orf19.4836 2136843 2138458 1 2136843 2138458 2137047 2138381 URA1 orf19.12299|IPF22436.1|IPF4487.2|Contig4-3078_0020|orf6.7375|CA4745|CaO19.12299|CaO19.4836 Dihydroorotate dehydrogenase (DHODH); enzyme of de novo pyrimidine biosynthesis; putative bipartite mitochondrial targeting motif, membrane spanning region; transcription is regulated upon yeast-hyphal switch, or by Nrg1p, Mig1p, Tup1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2138496 2139715 - orf19.4837.1 2138496 2139715 1 2139715 2138496 2139134 2138814 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2138538 2139494 + orf19.4837 2138538 2139494 1 2138538 2139494 2138563 2139396 orf19.12300|IPF22462.1|IPF4489.2|Contig4-3078_0019|orf6.7374|CA4744|CaO19.4837|CaO19.12300|IPF4489 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2139804 2140842 + orf19.4839 2139804 2140842 1 2139804 2140842 2139855 2140751 orf19.12302|IPF22455.1|IPF4491.1|Contig4-3078_0017|orf6.7372|CA4743|CaO19.4839|CaO19.12302|IPF4491 Predicted ORF in Assemblies 19, 20 and 21; decreased expression observed in an ssr1 homozygous null mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2140745 2141951 - orf19.4841 2140745 2141951 1 2141951 2140745 2141907 2140828 SHY1 orf19.12304|IPF22446.1|IPF4494.1|Contig4-3078_0016|orf6.7370|CA4742|CaO19.4841|CaO19.12304 Transcription is regulated by Nrg1p and Mig1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2142313 2142825 + orf19.4842 2142313 2142825 1 2142313 2142825 2142338 2142679 orf19.12305|IPF22509.1|IPF4495.1|Contig4-3078_0014|orf6.7369|CaO19.12305|CaO19.4842 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2142655 2145204 - orf19.4843 2142655 2145204 1 2145204 2142655 2144968 2142773 orf19.12306|IPF22381.1|IPF4496.1|Contig4-3078_0013|orf6.7368|CA4741|CaO19.4843|CaO19.12306|IPF4496 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2145320 2146726 - orf19.4844 2145320 2146726 1 2146726 2145320 2146676 2145531 orf19.12307|IPF22442.1|IPF4497.2|Contig4-3078_0012|orf6.7367|CA4740|CaO19.12307|CaO19.4844|IPF4497 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2146926 2147843 - orf19.4845 2146926 2147843 1 2147843 2146926 2147583 2147062 orf19.12308|IPF22486.1|IPF4498.2|Contig4-3078_0010|orf6.7366|CA4739|CaO19.12308|CaO19.4845|IPF4498 Predicted ORF in Assemblies 19, 20 and 21; fluconazole-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2148217 2149566 + orf19.4846 2148217 2149566 1 2148217 2149566 2148256 2149497 orf19.12309|IPF4500|IPF22439.1|IPF4500.1|Contig4-3078_0008|orf6.7365|CA4738|CaO19.12309|CaO19.4846 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2148453 2148905 - orf19.4847 2148453 2148905 1 2148905 2148453 2148905 2148453 IPF22481.1|IPF4499.1|orf6.7364 ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2149739 2154111 + orf19.4848 2149739 2154111 1 2149739 2154111 2149827 2154029 SKI3 orf19.12311|IPF22503.1|IPF4502.1|Contig4-3078_0006|orf6.7363|CA4737|CaO19.4848|CaO19.12311 Protein similar to S. cerevisiae Ski3p, which is required for repressing propagation of dsRNA viruses [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2154052 2155285 - orf19.4849 2154052 2155285 1 2155285 2154052 2155073 2154090 orf19.12312|IPF22448.1|IPF4503.2|Contig4-3078_0005|orf6.7362|CA4736|STS1|CaO19.12312|CaO19.4849|IPF4503 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2155773 2155967 + ntar_199 2155773 2155967 1 2155773 2155967 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2155974 2158129 - orf19.4850 2155974 2158129 1 2158129 2155974 2157940 2156090 orf19.12313|IPF22396.1|IPF7726.2|Contig4-2920_0017|Contig4-3078_0001|orf6.7361|CA4735|CaO19.4850|CaO19.12313|IPF7726 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2158508 2160003 - orf19.4851 2158508 2160003 1 2160003 2158508 2159971 2158787 TFA1 orf19.12314|IPF22440.1|IPF7729.1|Contig4-2920_0015|orf6.7360|CA4734|CaO19.12314|CaO19.4851 Protein with polyglutamate motifs and abundant Ser/Thr residues; described as a subunit of TFIIE, which is a basal transcription initiation factor of RNA Polymerase II [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2161277 2163420 + orf19.4853 2161277 2163420 1 2161277 2163420 2161492 2163231 HCM1 orf19.12316|orf6.7358|IPF22406.1|IPF7732.2|Contig4-2920_0014|CA4733|CaO19.4853|CaO19.12316|IPF7732 Protein with forkhead domain; similar to S. cerevisiae Hcm1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2163383 2164133 - orf19.4855 2163383 2164133 1 2164133 2163383 2164013 2163561 BUD31 orf19.12318|IPF22484.1|IPF7733.1|Contig4-2920_0013|orf6.7356|CA4732|CaO19.4855|CaO19.12318|IPF7733 Not subject to mating-type regulation, in contrast to the S. cerevisiae ortholog, which has a role in specification of the bud site [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2163534 2163706 + ntar_200 2163534 2163706 1 2163534 2163706 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2164292 2164386 - ts(cga)1 2164292 2164386 2 2164386|2164336 2164350|2164292 tS(CGA)1.2 tRNA-Ser predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2164391 2164661 + ntar_201 2164391 2164661 1 2164391 2164661 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2166143 2167558 + orf19.4856 2166143 2167558 1 2166143 2167558 2166143 2167558 LIP3 orf19.12319|IPF22432.1|IPF7736.2|Contig4-2920_0010|orf6.7355|CA4731|CaO19.4856|CaO19.12319 Secreted lipase, member of a lipase gene family whose members are expressed differentially in response to carbon source and during infection; may have a role in nutrition and/or in creating an acidic microenvironment [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2167588 2168979 - orf19.4857 2167588 2168979 1 2168979 2167588 2168519 2167701 orf19.12320|IPF7737.2|IPF28260.1|Contig4-2920_0009|orf6.7354|CA4730|CaO19.12320|CaO19.4857|IPF7737 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2169433 2169628 + ntar_202 2169433 2169628 1 2169433 2169628 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2169745 2172959 + orf19.4858 2169745 2172959 1 2169745 2172959 2169829 2172714 VPS41 orf19.12321|orf19.12322|orf19.12323|IPF12249.2|IPF12250.3|IPF28261.1|IPF28247.1|IPF12252.2|IPF28264.1|Contig4-2920_0005|Contig4-2920_0006|orf6.7353|orf6.7352|orf6.687|CA4729|CA4728|orf19.4859|orf19.4860|VAM2|VPS41.5f Protein similar to S. cerevisiae Vps41p, which is involved in vacuole organization and biogenesis; transposon mutation affects filamentous growth; regulated by Gcn4p; induced in response to amino acid starvation (3-aminotriazole treatment) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2172733 2173628 - ntar_203 2172733 2173628 1 2173628 2172733 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2173072 2173884 + orf19.4861 2173072 2173884 1 2173072 2173884 2173072 2173884 orf19.12324|IPF12253.1|IPF19185.1|Contig4-2920_0002|orf6.688|orf6.7351|CA4727|CaO19.4861|IPF12253 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2173815 2174898 - orf19.4862 2173815 2174898 1 2174898 2173815 2174808 2174212 orf19.12326|IPF12255.2|IPF16153.2|Contig4-1868_0003|orf6.689|orf6.7349|CaO19.4862|CA4726|IPF12255 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2173946 2174230 + orf19.4861.1 2173946 2174230 1 2173946 2174230 2173946 2174230 IPF12254.2|IPF19184.1|orf6.7350 ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2174933 2175738 + orf19.4862.2 2174933 2175738 2 2174933|2175235 2175133|2175738 2175074 2175498 IPF16152.1|IPF12257.1|Contig4-1868_0004|CA4725|PET100 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2175496 2178351 - orf19.4863 2175496 2178351 1 2178351 2175496 2178173 2175663 PDC2 orf19.12327|IPF16151.2|IPF12258.2|Contig4-2286_0003|Contig4-2286_0005|orf6.442|orf6.690|orf6.7348|CA4724|CTA5|CaO19.4863 Transcriptional regulator of pyruvate decarboxylase; contains a putative C-terminal activation domain, Glu- and Pro-rich; complements glucose utilization defect of S. cerevisiae pdc2 mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2178707 2180075 - orf19.4864 2178707 2180075 1 2180075 2178707 2179911 2178997 orf19.12328|IPF18177.1|IPF16983.2|Contig4-2286_0002|orf6.441|orf6.7347|CA4723|YJU3|CaO19.4864|IPF18177 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2180919 2183131 + orf19.4865 2180919 2183131 1 2180919 2183131 2181078 2182934 orf19.12329|IPF15617.2|IPF16984.3|Contig4-2255_0013|orf6.440|orf6.7346|CA4722|SAC1|CaO19.4865 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2183131 2185581 - orf19.4866 2183131 2185581 1 2185581 2183131 2185137 2183344 CPP1 orf19.12330|IPF15616.2|IPF19180.2|Contig4-2255_0001|orf6.707|orf6.7345|CA4721|CaO19.4866 MAPK phosphatase of the VH1 family; regulates Cst20p-Hst7p-Cek1p-Cph1p hyphal growth pathway; required for wild-type virulence in mouse systemic infection; C516 is active site Cys; antigenic in human thrush; more mRNA in yeast than hyphae [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2185611 2186127 - ntar_204 2185611 2186127 1 2186127 2185611 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2185652 2186147 + ntar_205 2185652 2186147 1 2185652 2186147 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2189021 2192841 - orf19.4867 2189021 2192841 1 2192841 2189021 2192696 2189160 SWE1 orf19.12331|IPF10223.3|IPF28274.1|Contig4-1510_0001|Contig4-1510_0003|Contig4-2622_0001|orf6.2582|orf6.706|CA1200|CaO19.4867|IPF10223|IPF10223.2 Putative protein kinase with a role in control of growth and morphogenesis, required for full virulence; mutant cells are small, rounded, and sometimes binucleate; not required for filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2194863 2197051 + orf19.4869 2194863 2197051 1 2194863 2197051 2195405 2196958 SFU1 orf19.12333|orf6.2584|IPF22421.1|IPF19906.1|Contig4-2622_0003|Contig4-2622_0004|CA1201|CaO19.12333|CaO19.4869|IPF19906 Transcriptional regulator of iron-responsive genes; represses some iron utilization genes when iron is present; not required for wild-type hyphal growth; has two GATA1-like zinc fingers separated by Cys-rich iron-sensing region [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2197121 2198925 + orf19.4870 2197121 2198925 1 2197121 2198925 2197121 2198815 DBP3 orf19.12334|IPF10215.2|IPF17356.3|Contig4-2619_0001|Contig4-2622_0005|orf6.2585|orf6.3829|CA1202|CaO19.4870 Predicted ORF in Assemblies 19, 20 and 21; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2199550 2201906 + orf19.4871 2199550 2201906 1 2199550 2201906 2199912 2201654 ERO1 orf19.12335|IPF17353.3|IPF13354.2|Contig4-2619_0004|Contig4-2619_0005|orf6.2586|orf6.3830|CA2076|CaO19.4871 Protein described as similar to S. cerevisiae Ero1p, which has a role in formation of disulfide bonds in the endoplasmic reticulum; fluconazole-induced; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2202256 2203107 + orf19.4872 2202256 2203107 1 2202256 2203107 2202256 2203107 orf19.12336|IPF13353|IPF22461.1|IPF13353.1|Contig4-2619_0009|orf6.3831|CA2077|CaO19.12336|CaO19.4872 Protein not essential for viability; possibly spurious ORF (Annotation Working Group prediction); transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2203490 2204310 - orf19.4873 2203490 2204310 1 2204310 2203490 2204101 2203589 orf19.12337|IPF17929.2|IPF13352.1|Contig4-2619_0010|orf6.113|orf6.3832|CA2078|CaO19.4873|IPF13352 Predicted ORF in Assemblies 19, 20 and 21; expression is regulated upon white-opaque switching [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2205522 2207662 - orf19.4874 2205522 2207662 1 2207662 2205522 2207407 2205587 MNN3 orf19.12338|IPF22402.1|IPF13350.2|Contig4-2619_0014|Contig4-2619_0015|orf6.112|orf6.3833|CA2079|CaO19.4874|MNN23 Predicted Golgi alpha-1,2-mannosyltransferase; mutation confers hypersensitivity to toxic ergosterol analog, and to amphotericin B [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2208225 2209486 + orf19.4875 2208225 2209486 1 2208225 2209486 2208671 2209159 orf19.12339|IPF22483.1|IPF9693.2|orf6.3834|CA2080|CaO19.4875|CWC21|CaO19.12339|IPF9693 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2209365 2212097 - orf19.4878 2209365 2212097 1 2212097 2209365 2212048 2209502 orf19.12342|IPF22361.1|IPF9699.2|orf6.3837|CA2081|CaO19.12342|CaO19.4878|IPF9699 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2212150 2212927 - orf19.4879.2 2212150 2212927 2 2212927|2212757 2212867|2212150 2212873 2212390 NTF2 IPF22508.1|IPF9700.2|Contig4-2738_0001|CA2082 ORF Predicted by Annotation Working Group; regulated by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2214100 2216268 + orf19.4880 2214100 2216268 1 2214100 2216268 2214100 2216268 orf19.12344|IPF17533.2|IPF9703.2|IPF17532.3|Contig4-2738_0005|Contig4-2738_0006|orf6.3839|orf6.3840|orf6.1625|CA0598|CA6291|orf19.4881|CaO19.4880|YFW5|IPF9703.5f|IPF9703 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr1 2215891 2217406 - orf19.4882 2215891 2217406 1 2217406 2215891 2217342 2216488 orf19.12345|IPF9704.2|IPF28259.1|Contig4-2738_0007|orf6.1624|orf6.3841|CA0597|TFA2|CaO19.4882|IPF9704 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2217599 2218337 + ntar_206 2217599 2218337 1 2217599 2218337 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2217881 2220290 - orf19.4883 2217881 2220290 1 2220290 2217881 2220202 2217971 orf19.12346|IPF9706.2|IPF18549.2|Contig4-2738_0012|orf6.1623|orf6.3842|CA0596|CaO19.4883|IPF9706 Predicted ORF in Assemblies 19, 20 and 21; constitutive expression independent of MTL or white-opaque status [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2222244 2222420 - ntar_207 2222244 2222420 1 2222420 2222244 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2228559 2233168 + orf19.4884 2228559 2233168 1 2228559 2233168 2230537 2232894 WOR1 orf19.12348|IPF22376.1|IPF15255.2|Contig4-2464_0001|orf6.3050|CA1512|EAP2|TOS9|YEL007W|CaO19.4884|CaO19.12348|IPF15255 Transcriptional regulator ("master switch") of white-opaque phenotypic switching; required to establish and maintain the opaque state; opaque-specific, nuclear; regulates its own expression; suggested role in regulation of adhesion factors [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2236338 2237713 + orf19.4885 2236338 2237713 1 2236338 2237713 2236380 2237303 MIR1 orf19.12349|IPF22456.1|IPF7536.2|Contig4-2934_0003|orf6.3051|CA1513|CaO19.4885|CaO19.12349 Putative mitochondrial phosphate transporter; caspofungin repressed; expression is increased in a fluconazole-resistant isolate; induced upon adherence to polystyrene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2239176 2239892 + orf19.4886 2239176 2239892 1 2239176 2239892 2239176 2239892 orf19.12350|IPF22472.1|IPF7539.1|Contig4-2934_0006|orf6.3052|CA1514|CaO19.12350|CaO19.4886|IPF7539 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2240150 2242751 - orf19.4887 2240150 2242751 1 2242751 2240150 2242520 2240214 ECM21 orf19.12352|IPF18663.2|IPF7541.3|Contig4-2934_0009|orf6.3053|orf6.3331|ECM21.3|CA1707|CaO19.4887|CA1515|IPF18663.1 Protein not essential for viability; similar to S. cerevisiae Ecm21p (may have cell wall role); alkaline upregulated by Rim101p; fluconazole induced; caspofungin repressed; downregulated in azole-resistant strain overexpressing MDR1 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2245376 2246489 + orf19.4888 2245376 2246489 1 2245376 2246489 2245436 2246269 orf19.12353|IPF22460.1|IPF7543.2|Contig4-2934_0015|orf6.3332|CA1708|CaO19.12353|YRA1|CaO19.4888|IPF7543 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2246273 2248737 - orf19.4889 2246273 2248737 1 2248737 2246273 2248267 2246513 orf19.12354|IPF22405.1|IPF7544.2|Contig4-2934_0016|orf6.3333|CA1709|HOL1|CaO19.4889|CaO19.12354|HOL2 Predicted membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2249393 2252567 - orf19.4890 2249393 2252567 1 2252567 2249393 2252473 2249543 CLA4 orf19.12355|IPF15972.3|IPF16297.2|Contig4-2934_0017|orf6.3334|orf6.53|CA1710|CaO19.4890 S/T kinase of Ste20p family; required for wild-type filamentous growth and for wild-type organ colonization and virulence in mouse systemic infection; role in chlamydospore formation; functional homolog of S. cerevisiae Cla4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2252793 2252950 - ntar_208 2252793 2252950 1 2252950 2252793 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2255428 2257108 - orf19.4892 2255428 2257108 1 2257108 2255428 2256855 2255638 TPK1 orf19.12357|IPF12285.2|IPF18622.2|Contig4-2955_0006|orf6.3336|orf6.4228|CA2355|TPK3|CaO19.4892 Catalytic subunit of cAMP-dependent protein kinase (PKA), isoform of Tpk2p; involved in control of morphogenesis and stress response; wild-type nuclear localization requires Bcy1p; produced during stationary but not exponential growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2259227 2263829 - orf19.4893 2259227 2263829 1 2263829 2259227 2263716 2259391 orf19.12358|IPF12282|IPF22500.1|IPF12282.2|Contig4-2955_0011|Contig4-2955_0014|orf6.4229|CA2356|CaO19.12358|CaO19.4893 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2264029 2264907 - orf19.4894 2264029 2264907 1 2264907 2264029 2264847 2264113 orf19.12359|IPF22469.1|IPF8957.2|IPF8957|Contig4-2955_0017|orf6.4230|CA2357|CaO19.12359|CaO19.4894 Protein of unknown function, has similarity to S. cerevisiae Yer010cp, which is a protein of unknown function belonging to the prokaryotic RraA family; decreased transcription is observed upon benomyl treatment [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2265040 2265953 - orf19.4895 2265040 2265953 1 2265953 2265040 2265944 2265123 orf19.12360|IPF22453.1|IPF8953.2|Contig4-2955_0019|Contig4-2955_0021|orf6.4231|CA2358|CaO19.12360|CaO19.4895|IPF8953 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2266205 2267112 - orf19.4896 2266205 2267112 1 2267112 2266205 2267063 2266341 orf19.12361|IPF22470.1|IPF8952.1|Contig4-2955_0022|orf6.4232|CA2359|RPA34|CaO19.12361|CaO19.4896|IPF8952 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2267364 2268506 - orf19.4897 2267364 2268506 1 2268506 2267364 2268407 2267445 orf19.12362|IPF22451.1|IPF8951.2|Contig4-2955_0023|orf6.4233|CA2360|CaO19.4897|CaO19.12362|IPF8951 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2268633 2269501 - orf19.4898 2268633 2269501 1 2269501 2268633 2269357 2268668 orf19.12363|IPF8950.1|IPF28258.1|Contig4-2955_0025|orf6.4234|CA2361|CaO19.12363|CaO19.4898|IPF8950 Predicted ORF in Assemblies 19, 20 and 21; increased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2271539 2274379 + orf19.4899 2271539 2274379 1 2271539 2274379 2271539 2274379 GCA1 orf19.12365|MP190|IPF22352.1|IPF8948.2|AMYG1|Contig4-2932_0006|Contig4-2955_0029|orf6.2026|orf6.4236|orf6.5799|orf6.649|CA0855|CaO19.4899 Predicted extracellular or plasma membrane-associated glucoamylase; promotes biofilm matrix formation; possible adhesin; gene is transcribed during rat oral infection; transcription is regulated by carbohydrates, pH, galactose [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2273092 2273321 - ntar_209 2273092 2273321 1 2273321 2273092 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2276289 2279044 + orf19.4900 2276289 2279044 1 2276289 2279044 2276399 2278885 orf19.12366|IPF17635.3|IPF8854.2|Contig4-2409_0001|orf6.2025|orf6.4237|CA0854|CaO19.4900|IPF8854 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 2278801 2279364 - ntar_210 2278801 2279364 1 2279364 2278801 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2279768 2281146 + orf19.4901 2279768 2281146 1 2279768 2281146 2280112 2281146 orf19.12367|IPF18850.1|Contig4-2409_0004|orf6.2024|orf6.2023|orf6.1621|CA0595|CA6292|orf19.4902|CaO19.4901|IPF8856.5f|IPF8856|IPF8856.2 Predicted ORF in Assemblies 19, 20 and 21; merged with orf19.4902 in Assembly 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr1 2281308 2281916 + ntar_211 2281308 2281916 1 2281308 2281916 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2281961 2282224 - ntar_212 2281961 2282224 1 2282224 2281961 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2282064 2283498 + orf19.4903 2282064 2283498 1 2282064 2283498 2282361 2283422 orf19.12368|IPF8860.1|IPF28257.1|Contig4-2762_0010|orf6.1620|CA0594|CaO19.12368|GPI12|CaO19.4903|IPF8860 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2283263 2284812 - orf19.4904 2283263 2284812 1 2284812 2283263 2284784 2283444 orf19.12369|IPF22430.1|IPF8861.2|Contig4-2762_0009|orf6.1619|CA0593|CaO19.4904|ARP6|CaO19.12369 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2285421 2287271 + orf19.4905 2285421 2287271 1 2285421 2287271 2285620 2287173 orf19.12370|IPF8862.2|IPF28254.1|Contig4-2762_0006|orf6.1618|CA0592|CaO19.4905|IPF8862 Predicted ORF in Assemblies 19, 20 and 21; decreased expression observed in an ssr1 homozygous null mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2287182 2289577 - orf19.4906 2287182 2289577 1 2289577 2287182 2289577 2287271 orf19.12372|IPF17082.3|IPF8866.2|Contig4-2762_0005|orf6.1617|orf6.430|orf6.699|CA0076|CaO19.4906|IPF8866 Putative protein of unknown function, transcription is positively regulated by Tbf1p; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 2292642 2295120 - orf19.4907 2292642 2295120 1 2295120 2292642 2294809 2292992 orf19.12373|IPF22400.1|IPF17283.2|Contig4-2762_0012|orf6.3754|CA2021|CaO19.12373|CaO19.4907|IPF17283 Predicted ORF in Assemblies 19, 20 and 21; increased transcription is observed upon fluphenazine treatment; possibly transcriptionally regulated by Tac1p; induced by nitric oxide; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2295403 2295622 - ntar_213 2295403 2295622 1 2295622 2295403 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2295578 2295913 + orf19.4908 2295578 2295913 1 2295578 2295913 2295578 2295913 orf19.12374|IPF22515.1|IPF9610.2|Contig4-2018_0002|orf6.3755|CaO19.12374|CaO19.4908 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2296678 2299449 - orf19.4909 2296678 2299449 1 2299449 2296678 2299136 2296938 CBK1 orf19.12375|IPF22379.1|IPF9611.2|Contig4-2855_0009|orf6.3756|CA2022|CaO19.12375|CaO19.4909 Putative S/T kinase of cell wall integrity pathway; required for hyphal growth; mutant cells show abnormal morphology and aggregation; Mob2p associated; required for wild-type transcriptional regulation of several cell-wall-associated genes [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2296995 2297176 + ntar_214 2296995 2297176 1 2296995 2297176 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2299716 2300901 - orf19.4909.1 2299716 2300901 2 2300901|2300348 2300707|2299716 2300710 2300032 RPL42 IPF22520.1|IPF9613.2|Contig4-2508_0008|CA2023|RPL42.3 ORF Predicted by Annotation Working Group; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2301150 2302260 - orf19.4910 2301150 2302260 1 2302260 2301150 2302038 2301286 FGR41 orf19.12376|PGA35|IPF22465.1|IPF9616.1|Contig4-2508_0005|orf6.3757|CA2024|CaO19.12376|CaO19.4910|IPF9616 Putative GPI-anchored protein; transposon mutation affects filamentous growth; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2304036 2305399 + orf19.4911 2304036 2305399 1 2304036 2305399 2304212 2305174 orf19.8596|orf19.12377|IPF17046.3|IPF9618.2|IPF26300.1|IPF29610.1|Contig4-2508_0004|orf6.580|orf6.3758|CA2025|orf19.981|CaO19.4911|CaO19.12377|IPF9618 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2305250 2307357 - orf19.4912 2305250 2307357 1 2307357 2305250 2307229 2305295 orf19.8598|orf19.12378|IPF22445.1|IPF9619.2|IPF9924.2|IPF17048.2|Contig4-2508_0003|orf6.578|orf6.5815|orf6.3759|CA0121|orf19.983|CaO19.4912|CaO19.12378 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2307432 2308146 - ntar_215 2307432 2308146 1 2308146 2307432 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2309139 2310647 + orf19.984 2309139 2310647 1 2309139 2310647 2309139 2310647 PHO8 orf19.8599|orf6.5814|IPF26293.1|IPF9926.2|Contig4-2694_0008|CA3530|CaO19.8599|CaO19.984|IPF9926 Protein of unknown function; transcription is positively regulated by Rim101p; regulated by Tsa1p, Tsa1Bp in minimal media at 37 deg; possibly adherence-induced [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr1 2311158 2314090 + orf19.985 2311158 2314090 1 2311158 2314090 2311282 2313795 orf19.8600|IPF9929.2|IPF18934.2|Contig4-2694_0006|orf6.1594|orf6.5813|CA3529|CaO19.985|IPF9929 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2315098 2316381 + orf19.986 2315098 2316381 1 2315098 2316381 2315247 2316368 GLY1 orf19.8601|IPF9931.1|IPF6766.1|Contig4-2262_0004|Contig4-2694_0002|orf6.1595|orf6.5812|CA3528|GLY1-1|GLY1-2|GLY11|CaO19.986 L-threonine aldolase; possibly tetrameric; complements the glycine auxotrophy of an S. cerevisiae shm1 null shm2 null gly1-1 triple mutant; macrophage/pseudohyphal-induced; the GLY1 locus has an RFLP and is triploid in strain SGY269 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2316564 2318145 + orf19.988 2316564 2318145 1 2316564 2318145 2316720 2317952 orf19.8603|IPF9934.1|IPF6770.1|Contig4-2262_0003|Contig4-2694_0001|orf6.1597|orf6.5810|CA3527|CaO19.988|IPF9934 Predicted ORF in Assemblies 19, 20 and 21; fungal-specific (no human or murine homolog); transcription is upregulated in clinical isolates from HIV+ patients with oral candidiasis; possibly transcriptionally regulated upon hyphal formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2318281 2319629 + orf19.989 2318281 2319629 1 2318281 2319629 2318337 2319347 orf19.8604|IPF9936.2|IPF6773.2|IPF20059.1|Contig4-2262_0002|orf6.5809|orf6.1598|CA6251|CA3526|orf19.990.1|MRPS5|MRPS5.5f|MRPS5.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2319708 2321365 + orf19.991 2319708 2321365 1 2319708 2321365 2319827 2321353 DJP1 orf19.8606|orf6.5807|IPF6776.2|IPF18933.2|Contig4-2932_0022|CA3525|CaO19.991|CaO19.8606 Similar to bacterial DnaJ; reported to have a role in peroxisome biogenesis; transcriptionally regulated by iron; expression greater in low iron; induced upon adherence to polystyrene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2321596 2323579 + orf19.992 2321596 2323579 1 2321596 2323579 2321637 2323508 LKH1 orf19.8607|IPF26288.1|IPF6778.2|Contig4-2932_0021|orf6.5806|LKH1.3|CA3524|CaO19.8607|CaO19.992|LKH1.3f Protein repressed during the mating process; Hog1p-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2323934 2324874 + orf19.993 2323934 2324874 1 2323934 2324874 2324072 2324596 orf19.8608|IPF26298.1|IPF20135.1|Contig4-2932_0019|orf6.5805|CA3523|DOP98|CaO19.993|CaO19.8608|IPF20135 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2325499 2326958 - ntar_216 2325499 2326958 1 2326958 2325499 2326151 2325813 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2325641 2326189 + orf19.994 2325641 2326189 1 2325641 2326189 2325641 2326189 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2327329 2329275 + orf19.996 2327329 2329275 1 2327329 2329275 2327422 2329275 orf19.8611|IPF26290.1|IPF6784.2|Contig4-2932_0013|Contig4-2932_0014|orf6.5802|CA3521|LPF7|CaO19.8611|CaO19.996|IFA15 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chr1 2329619 2329892 - ntar_217 2329619 2329892 1 2329892 2329619 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2330036 2331004 + orf19.997 2330036 2331004 1 2330036 2331004 2330255 2330854 orf19.8612|IPF18325.2|IPF6785.1|Contig4-2932_0011|orf6.5801|CA3520|SNL1|CaO19.997|CaO19.8612|IPF6785 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2330811 2332636 - orf19.998 2330811 2332636 1 2332636 2330811 2332552 2330990 orf19.8613|IPF6787|IPF6787.1|IPF29608.1|Contig4-2932_0010|orf6.5800|CA3519|CaO19.8613|CaO19.998 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2332840 2335930 - orf19.999 2332840 2335930 1 2335930 2332840 2335782 2332942 GCA2 IPF16527.3|IPF16526.2|Contig4-2932_0004|orf6.5798|orf6.5799|CA3518|GCA1|AMYG2.5f|AMYG2|IPF6791.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 2333961 2334170 + ntar_218 2333961 2334170 1 2333961 2334170 2333961 2334146 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2336984 2339580 - orf19.1002 2336984 2339580 1 2339580 2336984 2339580 2337688 orf19.8618|IPF26289.1|IPF15371.2|orf6.5795|CA3517|CaO19.8618|LPF8|CaO19.1002|IFA22 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 2339779 2340053 + ntar_219 2339779 2340053 1 2339779 2340053 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2340578 2342386 - orf19.1005 2340578 2342386 1 2342386 2340578 2342386 2340578 orf19.8619|IPF19532.1|IPF18326.1|IPF15368.2|Contig4-1962_0003|orf6.5794|orf6.581|CA6182|orf19.1003|CaO19.1005|LPF10 Predicted ORF in Assemblies 19, 20 and 21; transcription is upregulated in both intermediate and mature biofilms [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2343905 2344838 - orf19.1830 2343905 2344838 1 2344838 2343905 2344641 2344309 orf19.9389|IPF25491.1|IPF16475.1|Contig4-1874_0001|orf6.1220|CaO19.9389|CaO19.1830 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2345045 2345272 + ntar_220 2345045 2345272 1 2345045 2345272 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2346663 2347357 + ntar_221 2346663 2347357 1 2346663 2347357 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2348403 2348572 + ntar_222 2348403 2348572 1 2348403 2348572 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2348672 2349094 - orf19.1831 2348672 2349094 1 2349094 2348672 2349094 2348672 IPF29291.1|Contig4-2756_0003|orf6.1221|CaO19.1831 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2349879 2351851 + orf19.1832 2349879 2351851 1 2349879 2351851 2349943 2351736 FCY23 orf19.9390|IPF10337.1|IPF29289.1|Contig4-2756_0005|orf6.4254|CA2374|CaO19.1832|TPN11|CaO19.9390 Putative transporter; Gcn4p-regulated; more similar to S. cerevisiae Tpn1p, which is a vitamin B6 transporter, than to purine-cytosine permeases [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2351555 2352310 - ntar_223 2351555 2352310 1 2352310 2351555 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2352474 2354143 + orf19.1833 2352474 2354143 1 2352474 2354143 2352602 2354041 orf19.9391|IPF25486.1|IPF10336.1|Contig4-2756_0007|orf6.4253|CA2373|CaO19.9391|CBF5|CaO19.1833 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2354109 2356979 - orf19.1834 2354109 2356979 1 2356979 2354109 2356937 2354205 orf19.9392|IPF25484.1|IPF10335.2|Contig4-2756_0008|Contig4-2756_0009|orf6.4252|CA2372|CaO19.1834|CaO19.9392|IPF10335 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 2357206 2359419 - orf19.1835 2357206 2359419 1 2359419 2357206 2359254 2357350 orf19.9393|IPF25485.1|IPF10333.2|Contig4-2756_0010|Contig4-2756_0011|orf6.4251|CA2371|CaO19.9393|CaO19.1835|IPF10333 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2361016 2362471 + orf19.1836 2361016 2362471 1 2361016 2362471 2361077 2362432 APN2 orf19.9394|IPF25487.1|IPF10847.1|Contig4-2684_0005|Contig4-2756_0014|orf6.4250|CA2370|CaO19.1836|CaO19.9394 Predicted ORF in Assemblies 19, 20 and 21; flucytosine induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2362001 2362433 - ntar_224 2362001 2362433 1 2362433 2362001 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2362615 2364006 + orf19.1837 2362615 2364006 1 2362615 2364006 2362662 2363378 TBP1 orf19.9395|IPF25489.1|IPF10845.1|Contig4-2684_0004|orf6.4249|CA2369|CaO19.1837|CaO19.9395 Transcription initiation factor; binds TATA box sequence, and binding does not require TFIIA; caspofungin repressed; functional homolog of S. cerevisiae and human TATA-binding proteins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2364134 2369345 - orf19.1839 2364134 2369345 1 2369345 2364134 2369345 2364348 RPA190 orf19.9397|IPF25490.1|IPF10842.2|Contig4-2684_0001|Contig4-2684_0002|orf6.4247|CA2368|CaO19.9397|CaO19.1839 Predicted ORF in Assemblies 19, 20 and 21;flucytosine induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2369621 2373569 - orf19.1840 2369621 2373569 2 2373569|2373405 2373497|2369621 2373535 2369758 orf19.9889|orf19.9398|IPF25488.1|IPF10840.2|IPF24966.1|IPF13383.2|orf6.4246|orf6.4199|CA6195|CA2336|orf19.2353|CaO19.1840|CaO19.9398|IPF10840.3eoc Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2373911 2375073 + orf19.2352 2373911 2375073 1 2373911 2375073 2374045 2375019 orf19.9888|IPF24994.1|IPF13379.2|Contig4-2380_0004|orf6.4200|CA2337|CaO19.2352|CaO19.9888|IPF13379 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2374912 2376016 - orf19.2351 2374912 2376016 1 2376016 2374912 2375969 2375064 NIT3 orf19.9887|IPF24993.1|IPF13378.1|Contig4-2380_0005|orf6.4201|CA2338|CaO19.9887|CaO19.2351 Predicted ORF in Assemblies 19, 20 and 21; regulated by Gcn2p and Gcn4p; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2376145 2377803 - orf19.2350 2376145 2377803 1 2377803 2376145 2377776 2376214 orf19.9886|IPF13377|IPF24976.1|IPF13377.2|Contig4-2380_0006|Contig4-2380_0007|orf6.4202|YOR378W|CA2339|CaO19.9886|CaO19.2350 Protein similar to S. cerevisiae Yor0378wp; transposon mutation affects filamentous growth; not essential for viability; member of MFS family of transporters; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2378638 2380759 - orf19.2347 2378638 2380759 1 2380759 2378638 2380617 2378824 MNN2 orf19.9883|MNN5|IPF19382.2|IPF15847.2|orf6.233|orf6.4205|CA2340|CaO19.2347|MNN25 Alpha-1,2-mannosyltransferase; likely involved in iron utilization in the endocytosis pathway under iron-limiting conditions; similar to S. cerevisiae Mnn2p and Mnn5p; transposon mutation affects filamentous growth; filament induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2381419 2383519 + orf19.2346 2381419 2383519 1 2381419 2383519 2381550 2383424 orf19.9882|IPF24974.1|IPF13838.2|Contig4-3011_0001|orf6.4206|CA2341|CaO19.9882|FMP40|CaO19.2346|IPF13838 Putative protein of unknown function, transcription is positively regulated by Tbf1p; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2383485 2384873 - orf19.2344 2383485 2384873 1 2384873 2383485 2384713 2383556 ASR1 orf19.9880|IPF13836|IPF24991.1|IPF13836.2|Contig4-3011_0003|orf6.4208|CA2342|CaO19.2344|DHN6 Protein described as similar to heat shock proteins; transcription regulated by cAMP, osmotic stress, ciclopirox olamine, ketoconazole; negatively regulated by Cyr1p, Ras1p; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 2385594 2385936 - ntar_225 2385594 2385936 1 2385936 2385594 2385719 2385594 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2386198 2386733 - orf19.2343.1 2386198 2386733 2 2386733|2386588 2386663|2386198 2386670 2386378 Pseudogene; added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2386820 2388377 + orf19.2343 2386820 2388377 1 2386820 2388377 2386859 2388307 VPS23 orf19.9879|IPF24985.1|IPF8671.2|Contig4-3011_0008|orf6.4209|CA2343|CaO19.2343|CaO19.9879|IPF8671 Protein involved in proteolytic activation of Rim101p, which regulates pH response; similar to S. cerevisiae Stp22p/Vps23p, which is a member of the ESCRT I protein sorting complex [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2388505 2389282 + orf19.2342 2388505 2389282 1 2388505 2389282 2388535 2389188 SFT2 orf19.9878|IPF25003.1|IPF8674.2|Contig4-3011_0009|orf6.4210|CA2344|SFT22|SFT21|CaO19.2342|CaO19.9878 Transcription is regulated by Mig1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2389103 2389951 - orf19.2341 2389103 2389951 1 2389951 2389103 2389729 2389271 HNT1 orf19.9877|IPF25010.1|IPF8675.2|Contig4-3011_0010|orf6.4211|CA2345|CaO19.2341|CaO19.9877 Predicted ORF in Assemblies 19, 20 and 21; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2390726 2393448 + orf19.2340 2390726 2393448 1 2390726 2393448 2390766 2393246 CDC48 orf19.9876|IPF8680.2|IPF29137.1|Contig4-3011_0012|orf6.5568|CA3333|CaO19.2340|CaO19.9876 Protein described as microsomal ATPase; regulated by Gcn2p and Gcn4p; induced in response to amino acid starvation (3-aminotriazole treatment); macrophage/pseudohyphal-repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2393436 2395279 - orf19.2337 2393436 2395279 1 2395279 2393436 2395239 2393608 ALP1 orf19.9873|IPF24975.1|IPF8681.1|Contig4-3011_0014|orf6.5571|CA3334|LYP2|CaO19.9873|CaO19.2337 Putative high-affinity basic amino acid permease; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2396292 2396900 + orf19.2336 2396292 2396900 1 2396292 2396900 2396292 2396900 orf19.9872|IPF25004.1|IPF8682.1|Contig4-3011_0016|orf6.5572|CA3335|CaO19.9872|CaO19.2336|IPF8682 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2396788 2398444 - orf19.2335 2396788 2398444 1 2398444 2396788 2398373 2396883 orf19.9871|IPF24979.1|IPF19983.1|Contig4-3011_0017|orf6.5573|CA3336|CaO19.2335|CaO19.9871|IPF19983 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to 5-fluorouracil (5-FU); Hog1p-induced; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2398572 2399695 + orf19.2334 2398572 2399695 1 2398572 2399695 2398600 2399568 BIG1 orf19.9870|IPF24995.1|IPF13583.2|Contig4-3011_0019|orf6.5574|CA3337|CaO19.2334|CaO19.9870|IPF13583 Protein of the endoplasmic reticulum required for beta-1,6-glucan synthesis, filamentation, adhesion, and virulence; ortholog of S. cerevisiae Big1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2399593 2401504 - orf19.2333 2399593 2401504 1 2401504 2399593 2401214 2399724 orf19.9869|IPF24983.1|IPF13582.2|Contig4-3011_0021|orf6.5575|CA3338|CaO19.9869|CaO19.2333|IPF13582 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2403598 2404392 + orf19.2332 2403598 2404392 1 2403598 2404392 2403598 2404392 orf19.9868|IPF24999.1|IPF20131.1|Contig4-2080_0004|Contig4-3011_0030|orf6.5576|CA3339|CaO19.2332|CaO19.9868|IPF20131 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2404282 2406211 - orf19.2331 2404282 2406211 1 2406211 2404282 2405785 2404448 ADA2 orf19.9867|IPF24987.1|IPF15288.1|Contig4-2080_0003|orf6.5577|CAS3|CA3340|CaO19.9867|CaO19.2331 Putative transcriptional coactivator; cell wall integrity role; required for wild-type transcriptional response to caspofungin; mutant is caspofungin hypersensitive; role in regulation with Cas5p; zinc finger DNA-binding motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2406458 2407578 + orf19.2329.1 2406458 2407578 2 2406458|2406974 2406594|2407578 2406592 2407384 RPS17B IPF25018.1|IPF15290.2|Contig4-2080_0001|CA3341|RPS17|RPS17.3 Putative ribosomal protein; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2407813 2409298 + orf19.2330 2407813 2409298 1 2407813 2409298 2407857 2409152 orf19.9866|IPF24986.1|IPF13361.2|orf6.5578|YOR205C|CA3342|CaO19.9866|UTP6|CaO19.2330|IPF13361 Predicted ORF in Assemblies 19, 20 and 21; transposon mutation affects filamentous growth; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2408807 2410098 - orf19.2328 2408807 2410098 1 2410098 2408807 2409985 2409149 orf19.9864|IPF24998.1|IPF13360.2|Contig4-2414_0001|orf6.5580|CA3343|CaO19.9864|CaO19.2328|IPF13360 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2410353 2410460 - ti(uau)1 2410353 2410460 2 2410460|2410388 2410424|2410353 tI(UAU)1.2 tRNA-Ile predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2410923 2412515 - orf19.2326 2410923 2412515 1 2412515 2410923 2412442 2410985 orf19.9862|IPF24982.1|IPF13359.2|Contig4-2414_0003|Contig4-2414_0004|orf6.5582|CA3344|ESC2|CaO19.9862|CaO19.2326|IPF13359 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2412641 2414581 + orf19.2325 2412641 2414581 1 2412641 2414581 2412665 2414218 orf19.9861|IPF24978.1|IPF13357.2|Contig4-2414_0006|orf6.5583|CA3345|TFC6|CaO19.2325|CaO19.9861|IPF13357 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2414071 2415610 - orf19.2324 2414071 2415610 1 2415610 2414071 2415599 2414283 UBA4 orf19.9860|IPF24989.1|IPF13356.2|Contig4-2414_0007|orf6.5584|CA3346|CaO19.9860|CaO19.2324|IPF13356 Predicted ORF in Assemblies 19, 20 and 21; increased expression in response to prostaglandins; clade-associated gene expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2415765 2416694 - orf19.2322.3 2415765 2416694 2 2416694|2416345 2416408|2415765 2416629 2415911 IPF25016.1|IPF15563.2|Contig4-1946_0001|CA3347|ERP5 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2416828 2418349 - orf19.2320 2416828 2418349 1 2418349 2416828 2418349 2416868 orf19.9856|IPF24981.1|IPF15559.2|Contig4-1946_0004|orf6.5588|CA3348|CaO19.2320|RIO1|CaO19.9856 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2418454 2419516 + orf19.2318.1 2418454 2419516 2 2418454|2418649 2418578|2419516 2418540 2419305 IPF19588.1|IPF19589.2|Contig4-2539_0012|orf6.503|CA3349|IPF19588 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2419710 2422020 + orf19.2319 2419710 2422020 1 2419710 2422020 2419750 2421768 orf19.9855|IPF18350.2|IPF16479.2|Contig4-2539_0011|orf6.504|orf6.5589|CA0098|CaO19.2319|IPF16479 Predicted ORF in Assemblies 19, 20 and 21; downregulated in core stress response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2422966 2423899 + orf19.2317 2422966 2423899 1 2422966 2423899 2423366 2423899 orf19.9853|IPF25005.1|IPF13777.1|Contig4-2539_0007|orf6.5533|CA3299|CaO19.9853|CaO19.2317|IPF13777 Predicted ORF in Assemblies 19, 20 and 21; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr1 2423903 2425835 - orf19.2315 2423903 2425835 1 2425835 2423903 2425723 2424161 orf19.9851|IPF24980.1|IPF13780.2|Contig4-2539_0004|Contig4-2539_0005|orf6.5535|CA3300|RTG3|CaO19.2315|CaO19.9851 Putative transcription factor with bZIP DNA-binding motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2426191 2426927 - orf19.2314 2426191 2426927 1 2426927 2426191 2426899 2426492 orf19.9850|IPF25009.1|IPF13782.2|Contig4-2539_0003|orf6.5536|CA3301|CaO19.9850|CaO19.2314|IPF13782 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2427040 2428494 - orf19.2313 2427040 2428494 1 2428494 2427040 2428398 2427208 orf19.9849|IPF24990.1|IPF13784.2|Contig4-2539_0001|orf6.5537|CA3302|CaO19.9849|CaO19.2313|IPF13784 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2429153 2429351 + ntar_226 2429153 2429351 1 2429153 2429351 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2429339 2432072 - ntar_227 2429339 2432072 1 2432072 2429339 2431191 2431015 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2430115 2432154 + orf19.2312 2430115 2432154 1 2430115 2432154 2430115 2432154 orf19.9848|IPF24972.1|IPF15397.2|FRE3|FRE11|FRE42|Contig4-2919_0013|orf6.5538|CA3303|CFL11|CaO19.9848|CaO19.2312 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21; similar to ferric reductase Fre10p [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2432412 2433574 + orf19.2311 2432412 2433574 2 2432412|2432795 2432457|2433574 2432455 2433574 RPL82 orf19.9847|IPF25000.1|IPF11736.2|RPL8B-2|Contig4-2919_0011|orf6.5539|CA3304|RPL8A|CaO19.2311|CaO19.9847 Predicted ribosomal protein; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2433925 2434446 + orf19.2310.1 2433925 2434446 2 2433925|2434126 2433925|2434446 2434130 2434321 RPL29 IPF24965.1|IPF11737.2|CA3305 Ribosomal protein L29; transcription is induced upon germ tube formation; shows colony morphology-related gene regulation by Ssn6p; intron in 5'-UTR [label_first_exon=CGD label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2434657 2435748 + orf19.2310 2434657 2435748 2 2434657|2434840 2434757|2435748 2434657 2435635 orf19.9846|IPF24997.1|IPF11738.2|Contig4-2919_0009|orf6.5540|CA3306|CaO19.9846|CaO19.2310|IPF11738 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2435450 2435587 - ntar_228 2435450 2435587 1 2435587 2435450 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2435727 2437078 - orf19.2309.2 2435727 2437078 2 2437078|2436635 2437040|2435727 2437043 2435875 RPL2 IPF11739.1|IPF19095.2|Contig4-2919_0008|CA3307|RPL2.3 ORF Predicted by Annotation Working Group; shows downregulation in infected rabbit kidney in SC5314, but not NGY152, strain background [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2438098 2440482 + orf19.2309 2438098 2440482 1 2438098 2440482 2438200 2440317 orf19.9845|IPF11742.2|IPF19092.1|IPF19093.1|Contig4-2919_0005|orf6.5541|orf6.943|CA3308|PET127|PET127.5f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2441063 2441258 - ntar_229 2441063 2441258 1 2441258 2441063 2441219 2441097 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2441949 2443231 + orf19.2308 2441949 2443231 1 2441949 2443231 2442032 2443117 orf19.9844|IPF8806.2|IPF19091.2|Contig4-2919_0002|orf6.5542|CA3309|CaO19.2308|IPF8806 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2443222 2445105 - orf19.2307 2443222 2445105 1 2445105 2443222 2445056 2443425 orf19.9843|IPF24977.1|IPF8808.2|Contig4-2919_0001|orf6.5543|CA3310|PFS2|CaO19.2307|CaO19.9843 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2445533 2446302 + orf19.2306 2445533 2446302 1 2445533 2446302 2445609 2446145 orf19.9842|IPF25007.1|IPF8809.2|Contig4-2749_0015|orf6.5544|CA3311|CaO19.9842|CaO19.2306|IPF8809 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2445902 2446670 - orf19.2305 2445902 2446670 1 2446670 2445902 2446615 2446241 orf19.9841|IPF25017.1|IPF8810.1|Contig4-2749_0014|orf6.5545|CA3312|GIM4|CaO19.2305|CaO19.9841|IPF8810 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2446876 2448032 - orf19.2304 2446876 2448032 1 2448032 2446876 2447981 2446953 orf19.9840|IPF24992.1|IPF8811.2|Contig4-2749_0012|orf6.5546|YIL041W|CA3313|CaO19.2304|CaO19.9840|IPF8811 Protein similar to S. cerevisiae Yil041wp; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2448598 2449488 + orf19.2303 2448598 2449488 1 2448598 2449488 2448714 2449415 FGR16 orf19.9839|IPF25001.1|IPF8812.2|Contig4-2749_0011|orf6.5547|CA3314|PRP38|CaO19.2303|CaO19.9839|IPF8812 Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth; fluconazole-downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2449657 2451282 + orf19.2302 2449657 2451282 1 2449657 2451282 2449721 2451190 orf19.9838|IPF24984.1|IPF8814.2|Contig4-2749_0008|Contig4-2749_0009|orf6.5548|CA3315|CSG2|CaO19.9838|CaO19.2302|IPF8814 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2450334 2450504 - ntar_230 2450334 2450504 1 2450504 2450334 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2450778 2451197 - ntar_231 2450778 2451197 1 2451197 2450778 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2451437 2452225 + orf19.2301 2451437 2452225 1 2451437 2452225 2451516 2452211 orf19.9837|IPF25002.1|IPF8817.2|Contig4-2749_0007|orf6.5549|CA3316|CaO19.2301|CaO19.9837|IPF8817 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2452045 2452678 - orf19.2299 2452045 2452678 1 2452678 2452045 2452546 2452241 orf19.9835|IPF25027.1|IPF8818.2|orf6.5551|CA3317|URM1|CaO19.2299|CaO19.9835 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2452991 2454426 + orf19.2298 2452991 2454426 1 2452991 2454426 2453068 2454381 orf19.9834|IPF24988.1|IPF8820.1|Contig4-2749_0003|orf6.1375|orf6.5552|CA3318|WBP1|CaO19.9834|CaO19.2298 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2454042 2454652 - ntar_232 2454042 2454652 1 2454652 2454042 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2454769 2456263 + orf19.2297 2454769 2456263 1 2454769 2456263 2455016 2455786 ARL3 orf19.9833|IPF8822.3|IPF14275.1|Contig4-2749_0002|orf6.1374|orf6.5553|CA0447|CaO19.2297|IPF14275 Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide in yhb1 mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2457070 2465020 + orf19.2296 2457070 2465020 1 2457070 2465020 2457135 2464790 orf19.8300|orf19.9831|IPF25023.1|IPF14282.3|IPF7715.3|IPF29744.1|Contig4-2776_0014|orf6.1793|orf6.3697|orf6.1373|CA0446|CA0706|orf19.682|CaO19.2296|IPF14282.5eoc|IPF14282|IPF14282.2 Predicted ORF in Assemblies 19, 20 and 21; similar to mucins; ketoconazole-induced; fluconazole-downregulated; greater mRNA abundance observed in a cyr1 homozygous null mutant than in wild type; colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 2464996 2467311 - orf19.681 2464996 2467311 1 2467311 2464996 2467031 2465127 HAP43 orf19.8298|orf6.1795|IPF7711.2|IPF18253.2|Contig4-2776_0004|orf6.6574|CA0707|CaO19.681|IPF7711 CCAAT-binding factor (CBF)-dependent transcription factor required for iron-limitation response; similar to transcription factor AP-1; transcription is negatively regulated by Sfu1p; ciclopirox olamine induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2468051 2469681 - orf19.680 2468051 2469681 1 2469681 2468051 2469636 2468227 orf19.8297|IPF18893.2|IPF7706.2|Contig4-2776_0008|orf6.1796|orf6.6573|CA4115|TIM50|CaO19.680|IPF7706 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2469795 2470538 + orf19.679 2469795 2470538 1 2469795 2470538 2469859 2470422 FGR39 orf19.8296|IPF26643.1|IPF7704.2|Contig4-2776_0010|orf6.6572|CA4114|CaO19.8296|CaO19.679|IPF7704 Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2470418 2471449 - orf19.677 2470418 2471449 1 2471449 2470418 2471379 2470558 CHO1 orf19.8294|IPF26635.1|IPF7703.2|Contig4-2776_0011|orf6.6570|CA4113|CaO19.8294|CaO19.677 Putative phosphatidylserine synthase; similar to S. cerevisiae Cho1p, which is involved in phosphatidylserine biosynthesis; transposon mutation affects filamentous growth; regulated by Nrg1p, Tup1p; no human or murine homolog [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2472627 2473723 + orf19.676 2472627 2473723 1 2472627 2473723 2472723 2473619 orf19.8293|IPF26634.1|IPF7699.2|Contig4-2917_0021|orf6.6569|CA4112|CaO19.676|BIM1|CaO19.8293 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2473688 2474168 - orf19.675.1 2473688 2474168 1 2474168 2473688 2474092 2473955 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2474600 2474876 - ntar_233 2474600 2474876 1 2474876 2474600 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2475428 2476355 + orf19.675 2475428 2476355 1 2475428 2476355 2475597 2476235 orf19.8292|orf6.131|IPF7692.2|IPF3964.2|Contig4-2917_0017|orf6.6568|CA4111|CaO19.675|IPF3964 Similar to cell wall proteins; induced in core stress response, core caspofungin response; iron-regulated; amphotericin B induced; regulated by Cyr1p, Ssn6p; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2476545 2478074 + orf19.674 2476545 2478074 1 2476545 2478074 2476813 2477904 orf19.8291|IPF26630.1|IPF3965.2|Contig4-2917_0014|orf6.6567|CA4110|CWC2|CaO19.8291|CaO19.674|IPF3965 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2478125 2479234 + orf19.673 2478125 2479234 1 2478125 2479234 2478125 2479234 orf19.8290|IPF26633.1|IPF3967.2|Contig4-2917_0012|orf6.6566|CA4109|CaO19.8290|OYE98|CaO19.673|IPF3967 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2478851 2481004 - orf19.672 2478851 2481004 1 2481004 2478851 2480984 2479239 orf19.8289|IPF26626.1|IPF3968.1|Contig4-2917_0010|Contig4-2917_0011|orf6.6565|CA4108|CaO19.8289|PRP28|CaO19.672|IPF3968 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2481131 2483836 - orf19.671 2481131 2483836 1 2483836 2481131 2483510 2481501 PSP1 orf19.8288|IPF26617.1|IPF3970.2|Contig4-2917_0009|orf6.6564|CA4107|CaO19.671|IPF3970 Protein repressed during the mating process [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2484061 2484575 + ntar_234 2484061 2484575 1 2484061 2484575 2484061 2484276 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2485023 2485756 - orf19.670.2 2485023 2485756 2 2485756|2485474 2485557|2485023 2485587 2485275 IPF26615.1|IPF20159.1|CA4106|IPF20159 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2486263 2486782 + ntar_235 2486263 2486782 1 2486263 2486782 2486263 2486448 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2486955 2487529 - orf19.670 2486955 2487529 1 2487529 2486955 2487456 2487148 SMT3 orf19.8287|IPF26656.1|IPF20158.1|Contig4-2322_0001|Contig4-2917_0002|orf6.6563|CA4105|CaO19.8287|CaO19.670 SUMO, small ubiquitin-like protein; Smt3p-conjugated proteins localize to septation site and mother side of bud neck; C. albicans septins appear not to be Smt3p-modified, in contrast to S. cerevisiae septins; similar to S. cerevisiae Smt3p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2487975 2489846 + orf19.669 2487975 2489846 1 2487975 2489846 2487975 2489846 PRM1 orf19.8286|IPF26621.1|IPF20157.1|Contig4-2322_0003|Contig4-2322_0006|orf6.6562|CA4104|CaO19.8286|CaO19.669|IPF20157 Protein induced during the mating process [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2489799 2491516 - orf19.668 2489799 2491516 1 2491516 2489799 2491386 2489908 orf19.8285|IPF26628.1|IPF3980.2|Contig4-2322_0007|orf6.6561|CA4103|CaO19.8285|CaO19.668|IPF3980 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2491983 2493102 + orf19.667.1 2491983 2493102 2 2491983|2492497 2492144|2493102 2492138 2492762 RPL37B IPF26651.1|IPF20156.1|Contig4-2094_0006|CA4102 Predicted ribosomal protein [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2492937 2495282 - orf19.666 2492937 2495282 1 2495282 2492937 2495200 2493020 orf19.8283|orf19.8284|IPF26629.1|IPF26636.1|IPF3984.2|IPF3985.2|Contig4-2094_0003|Contig4-2094_0005|Contig4-2322_0011|orf6.6559|orf6.6560|CA4100|CA4101|orf19.667|IPF3985 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2495660 2496856 + orf19.665 2495660 2496856 1 2495660 2496856 2495756 2496559 NEP1 orf19.8282|IPF26637.1|IPF3986.2|Contig4-2094_0002|orf6.6558|CA4099|CaO19.665|CaO19.8282|IPF3986 Protein of unknown function; ortholog of S. cerevisiae Emg1p, which is involved in ribosome biogenesis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2497091 2497825 + orf19.664 2497091 2497825 1 2497091 2497825 2497091 2497825 orf19.8281|IPF26638.1|IPF3988.2|orf6.6557|CA4098|CaO19.664|CaO19.8281|IPF3988 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2497745 2502256 - orf19.663 2497745 2502256 1 2502256 2497745 2501997 2497948 GIN4 orf19.8280|IPF26652.1|IPF3994.2|Contig4-2788_0002|orf6.6556|CA4097|CaO19.8280|CaO19.663 Kinase involved in pseudohyphal-to-hyphal switch; phosphorylates Cdc11p on S395 (regulatory); autophosphorylates; necessary for septin ring within germ tube, but not for septin band at mother cell junction; role in cytokinesis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2503392 2504080 - orf19.8278 2503392 2504080 1 2504080 2503392 2503966 2503625 Predicted ORF from original SGTC Assembly 19 annotation, removed from the reduced ORF set by the SGTC; subsequently reinstated in Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2504139 2505389 + orf19.661 2504139 2505389 1 2504139 2505389 2504197 2505273 KRR1 orf19.8277|IPF3997.3|IPF4000.2|Contig4-2788_0008|orf6.254|orf6.6554|CA4096|CaO19.661 Decreased transcription is observed upon benomyl treatment or in an azole-resistant strain that overexpresses MDR1; induced upon biofilm formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2504855 2505089 - ntar_236 2504855 2505089 1 2505089 2504855 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2506043 2508324 + orf19.660 2506043 2508324 1 2506043 2508324 2506221 2508167 orf19.8276|IPF26622.1|IPF4002.2|Contig4-2788_0013|orf6.6553|CA4095|CaO19.660|CaO19.8276|IPF4002 Putative protein of unknown function; mRNA binds to She3p; predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2508147 2512007 - orf19.658 2508147 2512007 1 2512007 2508147 2511975 2508271 GIN1 orf19.8274|IPF4004|IPF16455.3|IPF4004.2|Contig4-2788_0014|orf6.2188|orf6.6551|CA4094|MRC1|CaO19.658 Protein involved in regulation of DNA-damage-induced filamentous growth; putative component of DNA replication checkpoint; ortholog of S. cerevisiae Mrc1p, an S-phase checkpoint protein [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2512457 2513100 + ntar_237 2512457 2513100 1 2512457 2513100 2512457 2512669 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2513493 2514836 - orf19.657 2513493 2514836 1 2514836 2513493 2514777 2513620 SAM2 orf19.8272|IPF26631.1|IPF15535.2|Contig4-2279_0002|orf6.2190|CA0959|CaO19.657|CaO19.8272 S-adenosylmethionine synthetase, localizes to surface of hyphal cells, but not yeast-form cells; possible biofilm-induced expression (reports differ); alkaline upregulated; Hog1p-induced; farnesol-downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2515542 2515876 + ntar_238 2515542 2515876 1 2515542 2515876 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2515681 2516424 - ntar_239 2515681 2516424 1 2516424 2515681 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2516626 2517051 - ntar_240 2516626 2517051 1 2517051 2516626 2516799 2516650 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2516642 2517066 + ntar_241 2516642 2517066 1 2516642 2517066 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2517333 2518437 - orf19.656 2517333 2518437 1 2518437 2517333 2518372 2517560 DPP1 orf19.8271|IPF5432.1|IPF29743.1|Contig4-2315_0005|orf6.2191|CA0960|CaO19.656|CaO19.8271 Putative diacylglycerol pyrophosphate phosphatase of diacylglycerol production for phospholipid biosynthesis; downregulation correlates with clinical development of fluconazole resistance [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2522169 2524775 + orf19.655 2522169 2524775 1 2522169 2524775 2522395 2524032 PHO84 orf19.8269|orf19.8765|IPF26171.1|IPF7638.2|IPF26640.1|IPF5438.2|orf6.447|orf6.3437|CA1782|CA0083|orf19.1172|PHO84.5eoc Protein similar to high-affinity phosphate transporters; expression is regulated upon white-opaque switching or biofilm formation; Hog1p, ciclopirox olamine or alkaline induced; caspofungin or stress repressed; upregulated in RHE model [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2524768 2527061 - orf19.1171 2524768 2527061 1 2527061 2524768 2527061 2524803 orf19.8764|IPF26156.1|IPF7635.2|Contig4-2602_0002|orf6.3438|CA1783|CaO19.8764|CaO19.1171|IPF7635 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 2528029 2529405 - orf19.1170 2528029 2529405 1 2529405 2528029 2529344 2528538 ARO7 orf19.8763|IPF26168.1|IPF7632.1|Contig4-2602_0006|orf6.3439|CA1784|CaO19.1170|CaO19.8763 Putative chorismate mutase; fungal-specific (no human or murine homolog); alkaline upregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2528418 2528551 + ntar_242 2528418 2528551 1 2528418 2528551 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2528820 2529507 + ntar_243 2528820 2529507 1 2528820 2529507 2529301 2529507 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2529543 2530650 - orf19.1169 2529543 2530650 1 2530650 2529543 2530577 2529627 orf19.8762|IPF26167.1|IPF7631.2|Contig4-2602_0008|orf6.3440|CA1785|JID1|CaO19.1169|CaO19.8762|IPF7631 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2531124 2531986 - orf19.1168 2531124 2531986 1 2531986 2531124 2531948 2531361 ZCF3|orf19.8761|IPF7629.2|Contig4-2602_0009|orf6.3441|CA1786|CaO19.1168|CaO19.8761|IPF7629 Predicted zinc-finger protein of unknown function [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2532458 2533618 - orf19.1167 2532458 2533618 1 2533618 2532458 2533618 2532458 orf19.8760|IPF26164.1|IPF19929.1|Contig4-2394_0007|Contig4-2602_0012|orf6.3442|CA1787|TCD1|CaO19.8760|CaO19.1167|IFH3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr1 2534005 2538303 - orf19.1166 2534005 2538303 2 2538303|2538083 2538186|2534005 2538201 2534209 CTA3 orf19.8759|IPF26181.1|IPF7623.2|Contig4-2394_0005|Contig4-2394_0006|orf6.3443|CA1788|EDE1|USO1.3 Protein similar to S. cerevisiae Ede1p, which is involved in endocytosis; activates transcription in 1-hybrid assay in S. cerevisiae [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2538569 2539292 + orf19.1164 2538569 2539292 1 2538569 2539292 2538599 2539159 GAR1 orf19.8757|IPF13076.1|IPF7621.1|Contig4-2109_0005|Contig4-2394_0002|orf6.1613|orf6.3445|CA1789|CaO19.1164 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to tubercidin (7-deazaadenosine); macrophage/pseudohyphal-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2539097 2540514 - orf19.1163 2539097 2540514 1 2540514 2539097 2540436 2539345 orf19.8756|IPF13079.1|IPF7620.2|Contig4-2109_0003|orf6.1612|orf6.3446|CA0590|CaO19.8756|CaO19.1163|IPF13079 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2540598 2541226 + orf19.1162.1 2540598 2541226 2 2540598|2540709 2540628|2541226 2540598 2541211 IPF26174.1|IPF13080.1|Contig4-2109_0002|CA0589|IPF13080 ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGDmod orf_changed=false scenario_first_exon=Z scenario_last_exon=F] Ca21chr1 2541360 2541910 + orf19.1162 2541360 2541910 1 2541360 2541910 2541437 2541814 orf19.8755|IPF18931.2|IPF13081.2|Contig4-2109_0001|orf6.1611|CA0588|CaO19.8755|DOP99|CaO19.1162|IPF13081 Predicted ORF in Assemblies 19, 20 and 21; increased transcription is observed upon benomyl treatment [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2542103 2547491 + orf19.1161 2542103 2547491 1 2542103 2547491 2542332 2547464 PLD1 orf19.8753|IPF13085.3|IPF29560.1|orf6.1610|orf6.3136|CA0587|SPO14|CaO19.1161|CA1571|SPO14.3eoc|IPF7619.1|SPO14.5eoc|IPF13085.2 Phospholipase D1; required for phosphatidic acid and for most diacylglycerol production; required for wild-type mouse virulence, but not rat oral virulence; mutant defect in hyphal growth on solid substrates; similar to S. cerevisiae Spo14p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2547693 2548421 + orf19.1160 2547693 2548421 1 2547693 2548421 2547774 2548421 orf19.8752|IPF26172.1|IPF7617.2|Contig4-2834_0013|orf6.3135|CA1570|CaO19.1160|CaO19.8752|IPF7617 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2548377 2550074 - orf19.1159 2548377 2550074 1 2550074 2548377 2549999 2548479 orf19.8751|IPF26162.1|IPF7616.2|Contig4-2834_0012|orf6.3134|CA1569|CYS1|CaO19.8751|CaO19.1159|IPF7616 Predicted ORF in Assemblies 19, 20 and 21; similar to A. nidulans CYSA serine O-trans-acetylase, suggesting that C. albicans uses an O-acetyl-serine (OAS) pathway of sulfur assimilation; induced upon biofilm formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2550177 2551152 + orf19.1158 2550177 2551152 1 2550177 2551152 2550177 2551070 orf19.8750|IPF26169.1|IPF7615.1|Contig4-2834_0010|orf6.3133|CA1568|CaO19.1158|CaO19.8750|IPF7615 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 2551129 2552283 - orf19.1156 2551129 2552283 1 2552283 2551129 2552283 2551129 FUS1 orf19.8748|orf6.3131|IPF26166.1|IPF7613.1|Contig4-2834_0008|CA1567|CaO19.1156|CaO19.8748|IPF7613 Probable ortholog of S. cerevisiae Fus1p, which is a membrane protein required for mating; transcription is activated by Cph1p in mating type a cells, homozygous for the MTLa locus; alpha factor induced [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2552345 2553720 - orf19.1155 2552345 2553720 1 2553720 2552345 2553583 2552729 DPP2 orf19.8747|IPF26170.1|IPF7611.1|Contig4-2834_0007|orf6.3130|CA1566|CaO19.8747|DPP1|CaO19.1155 Predicted ORF in Assemblies 19, 20 and 21; similar to S. cerevisiae pyrophosphate phosphatase Lpp1p; possible role in farnesol biosynthesis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2554248 2555163 + orf19.1154 2554248 2555163 1 2554248 2555163 2554317 2554790 EGD1 orf19.8746|IPF26175.1|IPF7610.1|Contig4-2834_0004|orf6.3129|CA1565|CaO19.8746|CaO19.1154 Predicted ORF in Assemblies 19, 20 and 21; soluble protein in hyphae; biofilm induced; macrophage/pseudohyphal-induced; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2555756 2557685 + orf19.1153 2555756 2557685 1 2555756 2557685 2555881 2557587 GAD1 orf19.8745|IPF11712.3|IPF7609.1|Contig4-2834_0001|orf6.2779|orf6.3128|CA1564|CaO19.1153 Protein described as glutamate decarboxylase; macrophage-downregulated gene; alkaline downregulated; amphotericin B induced; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2558242 2559413 + orf19.1152 2558242 2559413 1 2558242 2559413 2558395 2559192 orf19.8744|IPF11713.1|IPF29561.1|IPF19733.2|Contig4-2773_0002|orf6.2780|orf6.3127|CA1330|CA6184|orf19.1151|CaO19.1152|IPF11713.5f Predicted ORF in Assemblies 19, 20 and 21; regulated by Gcn2p and Gcn4p; induced in core stress response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2558369 2559521 - orf19.1150.1 2558369 2559521 1 2559521 2558369 2559483 2559262 IPF26154.1|IPF11714.1|CA1331|IPF11714 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2560894 2562678 + orf19.1150 2560894 2562678 1 2560894 2562678 2561059 2562477 orf19.8743|IPF26163.1|IPF11716.1|Contig4-2773_0006|orf6.2781|CA1332|CaO19.8743|CaO19.1150|IPF11716 Predicted ORF in Assemblies 19, 20 and 21; regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2562589 2564032 - orf19.1149 2562589 2564032 1 2564032 2562589 2563794 2562715 MRF1 orf19.8742|IPF11717.2|IPF14722.3|Contig4-2773_0007|orf6.100|orf6.2782|CA1333|ETR2|CaO19.1149 Protein similar to mitochondrial respiratory proteins; increased transcription observed upon benomyl treatment; induced by farnesol, nitric oxide, core stress response; oxidative stress-induced via Cap1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2564273 2564614 + ntar_244 2564273 2564614 1 2564273 2564614 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2564787 2565578 - orf19.1148 2564787 2565578 1 2565578 2564787 2565578 2564787 orf19.8740|IPF19912.1|IPF29559.1|Contig4-2773_0009|orf6.2784|CA1334|CaO19.1148|CIS312|IPF19912 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2567851 2568611 + orf19.1146 2567851 2568611 1 2567851 2568611 2568243 2568611 IPF29564.1|CaO19.1146 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2568844 2572474 + orf19.1144 2568844 2572474 1 2568844 2572474 2568844 2572209 orf19.8737|IPF26180.1|IPF13166.3|Contig4-2773_0012|orf6.2172|orf6.2787|CA0953|CaO19.1144|IPF13166|IPF13166.3eoc|IPF13166.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2572602 2573989 + orf19.1143 2572602 2573989 1 2572602 2573989 2572640 2573824 orf19.8736|IPF26165.1|IPF20069.1|orf6.2173|CA6246|CaO19.8736|CaO19.1143|IPF20069 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2574573 2576930 + orf19.1142 2574573 2576930 1 2574573 2576930 2574824 2576743 orf19.8735|IPF26160.1|IPF13162.2|Contig4-2171_0004|Contig4-2171_0005|orf6.2174|CA0954|AVT41|CaO19.1142|CaO19.8735|IPF13162 Predicted ORF in Assemblies 19, 20 and 21; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2576808 2577712 - orf19.1140 2576808 2577712 1 2577712 2576808 2577590 2576964 orf19.8733|IPF17749.2|IPF13160.2|Contig4-2171_0003|orf6.2176|CA0955|CaO19.1140|IPF13160 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2577946 2581182 - orf19.1139 2577946 2581182 1 2581182 2577946 2581086 2578162 orf19.8732|IPF17015.2|IPF29554.1|Contig4-2171_0008|orf6.1575|orf6.2177|CA0570|SVL3|CaO19.1139 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2583723 2585113 + orf19.1137 2583723 2585113 1 2583723 2585113 2584210 2584884 orf19.8730|IPF16571.2|IPF4687.1|Contig4-2562_0007|orf6.1573|orf6.783|CA0569|CDC8|CaO19.1137 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2584766 2585472 - orf19.1136 2584766 2585472 1 2585472 2584766 2585384 2584947 orf19.8729|IPF16570.2|IPF4688.1|Contig4-2562_0006|orf6.1572|orf6.782|CA0568|APS2|CaO19.1136 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2585539 2588187 + orf19.1135 2585539 2588187 1 2585539 2588187 2585659 2588094 CAS1 orf19.8728|IPF19699.2|IPF20050.1|IPF20065.1|Contig4-2562_0005|orf6.1571|orf6.1909|orf6.781|CA0779|orf19.3491|YKU701|CaO19.1135 Putative transcription factor with beta-barrel DNA-binding motif; mutation causes marginal increase in caspofungin sensitivity [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2588713 2588821 + ty(gua)1 2588713 2588821 2 2588713|2588786 2588749|2588821 tY(GUA)1.2 tRNA-Tyr predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2589199 2589292 + ty(gua)4 2589199 2589292 2 2589199|2589257 2589235|2589292 tRNA-Tyr predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2592232 2594878 + orf19.5282 2592232 2594878 2 2592232|2593343 2592391|2594878 2593345 2594787 orf19.12747|IPF4696|IPF21944.1|IPF4696.2|Contig4-3082_0045|orf6.7660|CA4970|CaO19.12747|CaO19.5282 Putative protein of unknown function; mRNA binds to She3p; decreased expression in hyphae compared to yeast-form cells; regulated by Efg1p and Efh1p; intron in 5'-UTR; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2595123 2599128 + orf19.5281 2595123 2599128 1 2595123 2599128 2595379 2599041 orf19.12746|IPF21985.1|IPF4697.2|Contig4-3082_0043|orf6.7661|CA4971|CaO19.5281|SCP160|CaO19.12746|IPF4697 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2600193 2602071 + orf19.5280 2600193 2602071 1 2600193 2602071 2600273 2601934 MUP1 orf19.12745|IPF21939.1|IPF4701.2|Contig4-3082_0038|orf6.7662|CA4972|CaO19.5280|CaO19.12745 Alkaline upregulated by Rim101p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2602212 2602937 + orf19.5279 2602212 2602937 1 2602212 2602937 2602277 2602699 orf19.12744|IPF21976.1|IPF4703.2|Contig4-3082_0036|orf6.7663|CA4973|CaO19.5279|MRPL51|CaO19.12744|IPF4703 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2603064 2604362 + orf19.5278 2603064 2604362 1 2603064 2604362 2603198 2604226 orf19.12743|IPF21955.1|IPF4704.1|Contig4-3082_0035|orf6.7664|CA4974|CaO19.5278|CMD2|CaO19.12743|IPF4704 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2604326 2605649 - orf19.5277 2604326 2605649 1 2605649 2604326 2605624 2604401 orf19.12742|IPF21953.1|IPF4706.1|Contig4-3082_0034|orf6.7665|CA4975|CaO19.12742|CaO19.5277|IPF4706 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2605840 2607204 + orf19.5276 2605840 2607204 1 2605840 2607204 2605879 2607126 orf19.12741|IPF21952.1|IPF4708.1|Contig4-3082_0031|orf6.7666|CA4976|CaO19.5276|THP1|CaO19.12741|IPF4708 Predicted ORF in Assemblies 19, 20 and 21; induced upon low-level peroxide stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2607376 2608829 + orf19.5275 2607376 2608829 1 2607376 2608829 2607454 2608677 orf19.12740|IPF21950.1|IPF4710.1|Contig4-3082_0030|orf6.7667|CA4977|CaO19.5275|CaO19.12740|IPF4710 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2608786 2609209 - ntar_245 2608786 2609209 1 2609209 2608786 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2610641 2613990 + orf19.5274 2610641 2613990 1 2610641 2613990 2610835 2613900 orf19.12739|IPF21996.1|IPF2065.2|Contig4-3082_0028|orf6.7668|CA4978|CaO19.12739|CAF120|CaO19.5274|IPF2065 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2614012 2615942 - orf19.5271 2614012 2615942 1 2615942 2614012 2615882 2614137 orf19.12736|IPF21938.1|IPF2062.1|Contig4-3082_0026|orf6.7671|CA4979|CaO19.12736|CaO19.5271|IPF2062 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2616938 2618200 + orf19.5270 2616938 2618200 1 2616938 2618200 2617074 2618096 orf19.12735|IPF21957.1|IPF2059.1|Contig4-3082_0023|orf6.7672|CA4980|CaO19.12735|CMD3|CaO19.5270|IPF2059 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2618103 2618790 - orf19.5269.1 2618103 2618790 1 2618790 2618103 2618557 2618303 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2619114 2620782 - orf19.5269 2619114 2620782 1 2620782 2619114 2620566 2619175 orf19.12734|IPF21945.1|IPF2057.1|Contig4-3082_0018|orf6.7673|CA4981|CaO19.12734|CaO19.5269|IPF2057 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2620859 2622002 + orf19.5268 2620859 2622002 1 2620859 2622002 2621014 2621526 orf19.12733|IPF21969.1|IPF2054.1|Contig4-3082_0015|orf6.7674|CA4982|CaO19.5268|NUT2|CaO19.12733 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2620917 2621690 - ntar_246 2620917 2621690 1 2621690 2620917 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2623953 2624906 + orf19.5267 2623953 2624906 1 2623953 2624906 2624074 2624559 orf19.12732|IPF21970.1|IPF2053.1|Contig4-3082_0012|orf6.7675|CA4983|CaO19.12732|CaO19.5267|IPF2053 Putative cell wall protein; downregulated in core caspofungin response; transcription is repressed in response to alpha pheromone in SpiderM medium; transcription repressed in ace2 null mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2624769 2626184 - orf19.5266 2624769 2626184 1 2626184 2624769 2626184 2624805 orf19.12731|IPF21948.1|IPF2052.1|Contig4-3082_0011|orf6.7676|CA4984|CaO19.5266|CaO19.12731|IPF2052 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr1 2626424 2629582 - orf19.5265 2626424 2629582 1 2629582 2626424 2629381 2626667 KIP4 orf19.12730|KINH|IPF21924.1|IPF2050.1|Contig4-3082_0007|Contig4-3082_0008|orf6.7677|CA4985|CaO19.5265|SMY1|CaO19.12730|IPF2050 Transposon mutation affects filamentous growth; filament induced; shows Mob2p-dependent hyphal regulation; regulated by Nrg1p, Tup1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2631799 2631997 - ntar_247 2631799 2631997 1 2631997 2631799 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2632107 2632532 + orf19.5264 2632107 2632532 1 2632107 2632532 2632107 2632532 orf19.12729|IPF21979.1|IPF28105.1|orf6.7678|CaO19.12729|CaO19.5264 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2632940 2634504 + orf19.5263 2632940 2634504 1 2632940 2634504 2633019 2634410 SER33 orf19.12728|IPF21949.1|IPF2046.1|Contig4-2701_0010|Contig4-2701_0011|orf6.7679|CA4986|SER3|CaO19.5263|CaO19.12728 Predicted enzyme of amino acid biosynthesis; Gcn4p-regulated; upregulated in biofilm; protein detected by mass spec in exponential and stationary phase cultures; S. cerevisiae ortholog is Gcn4p regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2634590 2635021 + orf19.5262 2634590 2635021 1 2634590 2635021 2634590 2635021 orf19.12727|IPF21975.1|IPF2045.1|Contig4-2701_0009|orf6.7680|CA4987|CaO19.5262|CaO19.12727|IPF2045 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2635329 2638386 + orf19.5260 2635329 2638386 1 2635329 2638386 2635462 2638320 RPN2 orf19.12725|orf19.12726|IPF21923.1|IPF2043.1|Contig4-2701_0006|Contig4-2701_0007|orf6.7682|orf6.7681|CA4988|orf19.5261|CaO19.12725|CaO19.5260 Transcription is regulated by Mig1p; caspofungin repressed; regulated by Gcn2p and Gcn4p; gene used for strain identification by multilocus sequence typing [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2638387 2639220 - orf19.5259 2638387 2639220 1 2639220 2638387 2639142 2638423 orf19.12724|IPF21962.1|IPF2041.2|Contig4-2701_0005|orf6.7683|CA4989|CaO19.12724|CaO19.5259|IPF2041 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2639259 2641209 - orf19.5258 2639259 2641209 1 2641209 2639259 2641174 2639294 orf19.12723|IPF21937.1|IPF2039.1|Contig4-2701_0004|orf6.7684|CA4990|CaO19.12723|CaO19.5258|IPF2039 Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2641926 2643683 + orf19.5257 2641926 2643683 1 2641926 2643683 2641966 2643558 LCB4 orf19.12722|IPF21943.1|IPF2037.1|Contig4-2701_0001|orf6.7685|CA4991|CaO19.12722|CaO19.5257 Putative sphingosine kinase; expression is Tac1p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2643690 2645045 - orf19.5256 2643690 2645045 1 2645045 2643690 2645045 2643690 orf19.12721|IPF21947.1|IPF2036.1|orf6.7686|CA4992|CaO19.5256|CaO19.12721|IPF2036 Predicted ORF in Assemblies 19, 20 and 21; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2645293 2647565 - orf19.5255 2645293 2647565 1 2647565 2645293 2647477 2645474 PXA2 orf19.12720|IPF21930.1|IPF2034.2|Contig4-3107_0029|orf6.7687|CA4993|CaO19.12720|CaO19.5255 Putative peroxisomal, half-size adrenoleukodystrophy protein (ALD or ALDp) subfamily ABC transporter; Gcn4p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2647676 2648338 - orf19.5254 2647676 2648338 1 2648338 2647676 2648269 2647889 orf19.12719|IPF21981.1|IPF2033.1|Contig4-3067_0001|orf6.7688|CA4994|CaO19.5254|CaO19.12719|IPF2033 Predicted ORF in Assemblies 19, 20 and 21; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2648515 2650991 + orf19.5253 2648515 2650991 1 2648515 2650991 2648700 2650898 orf19.12718|IPF21932.1|IPF2032.1|Contig4-3067_0003|orf6.7689|CA4995|CaO19.5253|CaO19.12718|IPF2032|YAK1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2650767 2653408 - orf19.5251 2650767 2653408 1 2653408 2650767 2653379 2650980 ZCF30|orf19.12716|IPF2029|IPF21928.1|IPF2029.1|Contig4-3067_0004|Contig4-3067_0005|orf6.7691|CA4996|CaO19.5251|CaO19.12716 Predicted zinc-finger protein of unknown function; not essential for viability; decreased transcription is observed upon fluphenazine treatment [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2653663 2654340 + orf19.5250 2653663 2654340 1 2653663 2654340 2653711 2654199 orf19.12715|IPF21972.1|IPF2027.1|Contig4-3067_0008|orf6.7692|CA4997|CaO19.5250|CaO19.12715|IPF2027 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2654160 2655072 - orf19.5249 2654160 2655072 2 2655072|2654828 2654898|2654160 2654955 2654278 orf19.12714|IPF21966.1|IPF2026.1|Contig4-3067_0009|orf6.7693|CA4998|CaO19.12714|CaO19.5249|IPF2026 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2655428 2656385 + orf19.5248 2655428 2656385 1 2655428 2656385 2655623 2656132 MSO1 orf19.12713|IPF21968.1|IPF2024.1|Contig4-3067_0011|orf6.7694|CA4999|CaO19.5248|CaO19.12713|IPF2024 Predicted ORF in Assemblies 19, 20 and 21; expression is down-regulated during pseudohyphal growth in the presence of lysed macrophages [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2656132 2657545 - orf19.5247 2656132 2657545 1 2657545 2656132 2657486 2656206 orf19.12712|IPF21951.1|IPF2023.2|Contig4-3067_0012|Contig4-3067_0013|orf6.7695|CA5000|CaO19.5247|CaO19.12712|IPF2023 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2657639 2658949 - orf19.5246 2657639 2658949 1 2658949 2657639 2658916 2657750 orf19.12711|IPF21954.1|IPF2022.1|Contig4-3067_0014|orf6.7696|CA5001|CaO19.5246|CaO19.12711|IPF2022 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2659343 2661558 + orf19.5245 2659343 2661558 1 2659343 2661558 2659343 2661511 orf19.12710|IPF21933.1|IPF2021.1|Contig4-3067_0016|Contig4-3067_0017|orf6.7697|CA5002|CaO19.12710|BUL4|CaO19.5245|IPF2021 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 2661727 2664794 + orf19.5244 2661727 2664794 1 2661727 2664794 2661825 2664740 MCD4 orf19.12709|IPF21997.1|IPF2019.2|Contig4-3067_0018|orf6.7698|CA5003|CaO19.5244|CaO19.12709 Protein of major facilitator superfamily; has phosphodiesterase/nucleotide pyrophosphatase domain; similar to S. cerevisiae Mcd4p, which acts in GPI anchor biosynthesis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2664927 2666594 + orf19.5243 2664927 2666594 1 2664927 2666594 2664966 2666528 TRP3 orf19.12708|IPF21941.1|IPF2018.2|Contig4-3067_0019|orf6.7699|CA5004|CaO19.12708|CaO19.5243 Predicted ORF in Assemblies 19, 20 and 21; regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2666984 2668695 + orf19.5242 2666984 2668695 1 2666984 2668695 2667057 2668502 CDC6 orf19.12707|IPF2017.3|IPF28100.1|Contig4-3067_0020|orf6.769|orf6.7700|CA6297|CDC62.3f|CA0178|IPF2017.2 Predicted ORF in Assemblies 19, 20 and 21; member of conserved Mcm1p regulon; periodic mRNA expression, peak at cell-cycle M/G1 phase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2668545 2668899 - ntar_248 2668545 2668899 1 2668899 2668545 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2669334 2672788 + orf19.5241 2669334 2672788 1 2669334 2672788 2669672 2672677 SNT1 orf19.12706|IPF12584|IPF2015.3|IPF12584.2|Contig4-3067_0022|orf6.768|orf6.7701|CA5006|CaO19.5241 Protein similar to S. cerevisiae Snt1p, which is an NAD-independent histone deacetylase; not essential for viability; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2672782 2674324 - orf19.5239 2672782 2674324 1 2674324 2672782 2674291 2672876 orf19.12703|IPF21946.1|IPF12579.2|Contig4-3067_0023|orf6.7703|CA5007|CaO19.5239|CaO19.12703|IPF12579 Predicted ORF in Assemblies 19, 20 and 21; oxidative stress-induced via Cap1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2674426 2676564 - orf19.5238 2674426 2676564 1 2676564 2674426 2676383 2674566 orf19.12702|IPF21935.1|IPF12577.2|Contig4-3067_0025|orf6.7704|CA5008|CaO19.5238|CaO19.12702|IPF12577 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2677459 2678228 + orf19.5237 2677459 2678228 1 2677459 2678228 2677581 2678222 orf19.12701|IPF21964.1|IPF13946.2|Contig4-3067_0029|orf6.7705|CA5009|VPH2|CaO19.12701|CaO19.5237 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2678359 2679446 + orf19.5236 2678359 2679446 2 2678359|2678682 2678616|2679446 2678377 2679386 orf19.12700|IPF21963.1|IPF13944.2|IPF21921.1|IPF13945.2|Contig4-3067_0030|Contig4-3067_0031|orf6.7706|CA5011|CA5010|orf19.5236.1|CaO19.5236|SRT1|CaO19.12700|IPF13944 Predicted ORF in Assemblies 19, 20 and 21; merged with orf19.5236.1 in Assembly 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2679228 2680284 - orf19.5235 2679228 2680284 1 2680284 2679228 2680237 2679539 orf19.12699|IPF13943|IPF21961.1|IPF13943.2|Contig4-3067_0032|orf6.7707|CA5012|CaO19.12699|CaO19.5235 Protein not essential for viability; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2680428 2682928 - orf19.5234 2680428 2682928 1 2682928 2680428 2682643 2680634 RBD1 orf19.12698|IPF11263.3|IPF13941.2|Contig4-3067_0034|orf6.2435|orf6.7708|CA5013|CaO19.5234|IPF13941 Rhomboid-like protein; similar to putative intramembrane serine proteases; involved in filamentous growth; Gcn4p-regulated; caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2683788 2684135 + orf19.5233 2683788 2684135 1 2683788 2684135 2683788 2684135 IPF21990.1|IPF28106.1|orf6.7709|CaO19.5233 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2685604 2686751 - orf19.5232 2685604 2686751 1 2686751 2685604 2686695 2685817 CSI2 orf19.12697|IPF11270.2|IPF28101.1|Contig4-2357_0002|orf6.2436|orf6.7710|CA1106|CaO19.5232|BRX1|IPF11270 Protein essential for growth; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2687159 2687688 - orf19.5231.2 2687159 2687688 1 2687688 2687159 2687617 2687414 IPF11271.2|IPF28096.1|CA1107|IPF11271 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2687973 2689208 + orf19.5231 2687973 2689208 1 2687973 2689208 2687973 2689208 orf19.12696|IPF11273.2|IPF18148.2|Contig4-2357_0007|orf6.2437|orf6.7711|CA1108|CaO19.5231|IPF11273 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2689281 2690459 - orf19.5230 2689281 2690459 1 2690459 2689281 2690384 2689374 MRPS9 orf19.12695|IPF21956.1|IPF11274.2|Contig4-2357_0008|orf6.2438|CA1109|CaO19.12695|CaO19.5230 Mitochondrial ribosomal protein S9; has N-terminal mitochondrial targeting signal and an S9 consensus motif; overexpression in S. cerevisiae causes respiratory defect that is reversible upon cessation of C. albicans gene expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2690852 2693991 + orf19.5229 2690852 2693991 1 2690852 2693991 2690877 2693891 orf19.12694|IPF21994.1|IPF10406.2|Contig4-1973_0007|Contig4-2357_0011|orf6.2439|CA1110|CaO19.12694|DIS3|CaO19.5229 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2693909 2695002 - orf19.5228 2693909 2695002 1 2695002 2693909 2694636 2694013 RIB3 orf19.12693|orf6.2440|IPF10407.2|IPF18577.2|Contig4-1973_0005|orf6.3689|CA1111|CaO19.5228|RIB3.5f 3,4-Dihydroxy-2-butanone 4-phosphate synthase; homodimeric enzyme of riboflavin biosynthesis; converts ribulose 5-phosphate to L-3,4-dihydroxy-2-butanone 4-phosphate; transcription regulated on yeast-hyphal switch, macrophage interaction [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2695794 2696661 + orf19.5227 2695794 2696661 1 2695794 2696661 2695968 2696465 orf19.12692|IPF18759.2|IPF10410.1|Contig4-1973_0002|orf6.2441|orf6.3688|CA1974|CaO19.5227|IPF10410 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2696438 2697992 - orf19.5226 2696438 2697992 1 2697992 2696438 2697872 2696598 WRS1 orf19.12691|IPF18578.2|IPF10411.2|Contig4-2921_0012|orf6.3687|CA1973|CaO19.5226|CaO19.12691 Putative tRNA-Trp synthetase; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2698087 2699362 - orf19.5225.2 2698087 2699362 2 2699362|2698734 2699151|2698087 2699181 2698355 RPL27A IPF19343.2|IPF10412.2|CA1972 Predicted ribosomal protein [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2699638 2700109 - orf19.5225 2699638 2700109 1 2700109 2699638 2700109 2699732 IPF10414.1|Contig4-2423_0001|orf6.3686|CaO19.5225 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2700359 2703193 - orf19.5224 2700359 2703193 1 2703193 2700359 2703193 2700359 orf19.12690|IPF17210.3|IPF10418.1|Contig4-2423_0002|orf6.320|orf6.3685|CA1971|CaO19.5224|PKH1|PKH2 Putative protein of unknown function; mRNA binds to She3p and is localized to hyphal tips; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2703358 2703785 - orf19.5223 2703358 2703785 1 2703785 2703358 2703785 2703387 IPF10862.3|IPF28108.1|Contig4-2423_0005|orf6.3684|CaO19.5223 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2704457 2707759 + orf19.5221 2704457 2707759 1 2704457 2707759 2704703 2707654 orf19.12688|IPF19391.2|IPF10863.2|orf6.3682|orf6.210|orf6.3683|CA1969|CA1970|orf19.5222|IPF18579.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2707878 2708966 + orf19.5220 2707878 2708966 1 2707878 2708966 2707934 2708791 orf19.12687|IPF21958.1|IPF10864.2|Contig4-2993_0009|orf6.3681|CA1968|CaO19.5220|REX4|CaO19.12687|IPF10864 Predicted ORF in Assemblies 19, 20 and 21; increased expression observed in an ssr1 homozygous null mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2708829 2717400 - orf19.5219 2708829 2717400 1 2717400 2708829 2717074 2709143 IRA2 orf19.12686|IPF21959.1|IPF10866.2|orf6.3680|CA1967|CaO19.5219|IPF10866 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 2718527 2718879 + ntar_249 2718527 2718879 1 2718527 2718879 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2718529 2719038 - orf19.69.2 2718529 2719038 1 2719038 2718529 2719038 2718745 IPF27195.1|IPF29971.1|Contig4-1654_0004|orf6.6543 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 2718980 2719122 + ntar_250 2718980 2719122 1 2718980 2719122 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2720131 2720868 + orf19.69 2720131 2720868 1 2720131 2720868 2720131 2720868 orf19.7723|IPF27193.1|IPF17131.2|orf6.1692|CA0644|CaO19.69|CaO19.7723|IPF17131 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction); transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr1 2720924 2722156 + orf19.68.2 2720924 2722156 2 2720924|2721196 2721109|2722156 2721027 2721529 IPF27197.1|IPF17130.1 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2721491 2721979 - ntar_251 2721491 2721979 1 2721979 2721491 2721694 2721533 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2722253 2727512 + orf19.3767 2722253 2727512 1 2722253 2727512 2722961 2727364 orf19.11251|PEP1|IPF23513.1|IPF15204.2|Contig4-3056_0041|orf6.3952|CA2171|CaO19.11251|CaO19.3767|PEP1.3eoc|PEP1.3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2727637 2727733 - tw(cca)1 2727637 2727733 2 2727733|2727672 2727697|2727637 tW(CCA)1.2 tRNA-Trp predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2729233 2733831 + orf19.3765 2729233 2733831 1 2729233 2733831 2729519 2733700 RAX2 orf19.11249|IPF23515.1|IPF15377.2|Contig4-2657_0017|orf6.3954|CA2172|CaO19.3765|CaO19.11249|IPF15377 Protein of unknown function; detected at yeast-form cell plasma membrane by mass spectrometry; transcription is filament induced and negatively regulated by Rim101p, Tup1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 2734093 2736593 + orf19.3764 2734093 2736593 1 2734093 2736593 2734270 2736549 GSG1 orf19.11248|IPF23501.1|IPF18527.1|orf6.3955|CA2173|CaO19.11248|CaO19.3764|IPF18527 Protein not essential for viability; similar to S. cerevisiae Gsg1p, which is a subunit of the TRAPP complex involved in targeting of ER-to-Golgi transport vesicles [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2736465 2738138 - orf19.3763 2736465 2738138 1 2738138 2736465 2738052 2736673 orf19.11247|IPF23505.1|IPF20096.1|Contig4-2804_0018|orf6.3956|CA2174|CaO19.3763|CaO19.11247|IPF20096 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2738325 2739109 + orf19.3762 2738325 2739109 1 2738325 2739109 2738399 2738935 orf19.11246|IPF23511.1|IPF8892.2|Contig4-2804_0015|orf6.3957|CA2175|CaO19.11246|CaO19.3762|IPF8892 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2738951 2741807 - orf19.3761 2738951 2741807 1 2741807 2738951 2741772 2739034 CDC54 orf19.11245|IPF8893.2|IPF18798.2|Contig4-2804_0013|orf6.2267|orf6.3958|CA2176|CaO19.3761|MCM4 Transcription is regulated by Nrg1p and Mig1p; periodic mRNA expression, peak at cell-cycle M/G1 phase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2742044 2743158 - orf19.3760 2742044 2743158 3 2743158|2742972|2742817 2743054|2742877|2742044 2743158 2742044 DLH1 orf19.11244|IPF18526.1|IPF23502.1|IPF23509.1|IPF28648.1|IPF8896.2|IPF8895.2|Contig4-2804_0012|orf6.2266|orf6.3959|CA1007|DLH1.3f [NOT TRANSCRIBED?] Functional homolog of S. cerevisiae Dmc1p, which is a meiosis-specific protein [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2743237 2744704 - orf19.3759 2743237 2744704 1 2744704 2743237 2744638 2743298 orf19.11243|IPF23508.1|IPF8898.2|Contig4-2804_0009|orf6.2265|CA1005|CaO19.11243|CaO19.3759|LPG7 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2744817 2746692 + orf19.3758 2744817 2746692 1 2744817 2746692 2745011 2746438 orf19.11242|IPF23507.1|IPF8901.2|Contig4-2804_0004|Contig4-2804_0006|orf6.2264|CA1004|CaO19.11242|CaO19.3758|IPF8901 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2746814 2747600 + orf19.3757 2746814 2747600 1 2746814 2747600 2746930 2747274 ATP20 orf19.11241|IPF23516.1|IPF8902.2|Contig4-2804_0001|orf6.2263|CA1003|CaO19.3757|CaO19.11241 Predicted ORF in Assemblies 19, 20 and 21; shows colony morphology-related gene regulation by Ssn6p; flucytosine induced; caspofungin repressed; macrophage/pseudohyphal-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2747682 2749675 - orf19.3756 2747682 2749675 1 2749675 2747682 2749675 2747753 CHR1 orf19.11240|IPF23503.1|IPF8903.2|Contig4-2804_0019|orf6.2262|CA1002|CaO19.3756|CaO19.11240|ROK1.3f|ROK1.3 Predicted DEAD-box ATP-dependent RNA helicase, functional homolog of S. cerevisiae Rok1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 2749725 2750806 + orf19.3755 2749725 2750806 1 2749725 2750806 2749794 2750456 orf19.11239|orf19.13720|IPF23510.1|IPF18800.1|IPF20807.1|IPF11656.2|Contig4-2678_0018|orf6.2261|orf6.5792|CA3515|orf19.6363|CaO19.3755|MRPL152|CaO19.11239 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2752332 2757111 + orf19.6362 2752332 2757111 1 2752332 2757111 2752581 2756981 SPA2 orf19.13719|orf6.5791|IPF20811.1|IPF11245.2|Contig4-2678_0013|CA3514|CaO19.13719|CaO19.6362|IPF11245 Protein involved in cell polarity, Spitzenkorper formation; required for mouse virulence; localizes to hyphal tip; has cell-cycle regulated localization in yeast-form cells; functional domains conserved with S. cerevisiae Spa2p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2757057 2757917 - orf19.6360 2757057 2757917 1 2757917 2757057 2757810 2757136 orf19.13717|IPF20805.1|IPF11246.2|Contig4-2678_0010|orf6.5789|CA3513|CWC15|CaO19.6360|CaO19.13717|IPF11246 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2758110 2759050 + orf19.6359 2758110 2759050 1 2758110 2759050 2758245 2758646 orf19.13716|IPF20812.1|IPF11247.2|Contig4-2678_0008|orf6.5788|CA3512|CaO19.13716|SOM1|CaO19.6359|IPF11247 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2758629 2759567 - orf19.6358 2758629 2759567 2 2759567|2759196 2759280|2758629 2759290 2758794 orf19.13715|IPF20810.1|IPF11248.2|Contig4-2678_0007|orf6.5787|CA3511|MMS2|CaO19.13715|CaO19.6358 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2759706 2761954 + orf19.6357 2759706 2761954 1 2759706 2761954 2759755 2761845 orf19.13714|IPF20796.1|IPF11251.2|Contig4-2678_0004|Contig4-2678_0005|orf6.5786|CA3510|MAD1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2761793 2764614 - orf19.6356 2761793 2764614 1 2764614 2761793 2764614 2761879 orf19.13713|IPF20795.1|IPF19783.1|Contig4-2678_0002|orf6.5785|CA3509|CaO19.6356|PRP6|CaO19.13713 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr1 2764752 2766517 + orf19.6355 2764752 2766517 1 2764752 2766517 2764811 2766364 orf19.13712|IPF20800.1|IPF11376.2|Contig4-2117_0001|orf6.5784|CA3508|RRB1|CaO19.6355|CaO19.13712|RSA2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2766313 2767192 - orf19.6354 2766313 2767192 1 2767192 2766313 2767100 2766450 orf19.13711|IPF20808.1|IPF11375.2|Contig4-2117_0002|orf6.5783|CA3507|CaO19.6354|CaO19.13711|IPF11375 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2767663 2769944 + orf19.6353 2767663 2769944 1 2767663 2769944 2768204 2769913 orf19.13710|IPF20797.1|IPF11374.2|orf6.5782|CA3506|LPF40|CaO19.6353|CaO19.13710|IFA5 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=G scenario_last_exon=G] Ca21chr1 2770205 2772028 - orf19.6351 2770205 2772028 1 2772028 2770205 2771901 2770498 orf19.13708|IPF19114.2|IPF11372.2|Contig4-2669_0002|orf6.5780|orf6.880|CA3505|CaO19.6351|IPF11372 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2772540 2772781 + ntar_252 2772540 2772781 1 2772540 2772781 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2772553 2773095 - orf19.6350 2772553 2773095 1 2773095 2772553 2773095 2772553 orf19.13707|IPF15889.1|IPF11369.2|Contig4-2300_0002|orf6.5779|orf6.879|CA3504|CaO19.6350|IPF11369 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2774410 2775990 + orf19.6349 2774410 2775990 1 2774410 2775990 2774814 2775821 RVS162 orf19.13706|IPF19115.1|IPF15890.2|Contig4-2300_0006|orf6.5778|orf6.877|orf6.878|CA3503|RVS99|CaO19.6349|IPF15890 Protein containing a BAR domain, which is found in proteins involved in membrane curvature; null mutant does not display the endocytic, hyphal growth, virulence, or cell wall defects exhibited by mutants in related genes RVS161 and RVS167 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2776637 2779680 + orf19.6348 2776637 2779680 1 2776637 2779680 2776744 2779569 orf19.13704|IPF14485|IPF19117.2|IPF14485.2|Contig4-2232_0003|Contig4-2232_0005|orf6.5777|orf6.876|CA3502|CaO19.6348 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2779567 2781222 - orf19.6347 2779567 2781222 1 2781222 2779567 2781210 2779648 orf19.13703|IPF20799.1|IPF14486.2|Contig4-2232_0002|orf6.5776|CA3501|CaO19.6347|CDC40|CaO19.13703 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2781333 2782477 + orf19.6346 2781333 2782477 1 2781333 2782477 2781378 2782343 orf19.13702|IPF20804.1|IPF14487.2|Contig4-2232_0001|orf6.5775|CA3500|CaO19.6346|IPF14487 Predicted ORF in Assemblies 19, 20 and 21; decreased transcription is observed in an azole-resistant strain that overexpresses MDR1 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2782520 2785459 + orf19.6345 2782520 2785459 1 2782520 2785459 2782583 2785375 RPG1A orf19.13701|IPF20794.1|IPF15252.2|Contig4-2851_0006|orf6.5774|CA3499|RPG1|CaO19.6345 Putative translation initiation factor; mutation confers hypersensitivity to roridin A and verrucarin A; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2785617 2786966 + orf19.6344 2785617 2786966 1 2785617 2786966 2785714 2786886 RBK1 orf19.13700|IPF20801.1|IPF15253.2|Contig4-2421_0007|orf6.5773|CA3498|CaO19.6344 Protein not essential for viability; similar to S. cerevisiae Rbk1p, which is a ribokinase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2787017 2789003 - orf19.6343 2787017 2789003 1 2789003 2787017 2788209 2787196 orf19.13699|IPF20802.1|IPF18329.1|orf6.5772|CA3497|FEN1|CaO19.6343|FEN11 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2789460 2790122 + orf19.6342 2789460 2790122 1 2789460 2790122 2789572 2790057 orf19.13698|IPF20806.1|IPF17064.2|Contig4-1616_0008|orf6.5771|CA3496|CaO19.6342|CaO19.13698|IPF17064 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2790259 2791328 + orf19.6341 2790259 2791328 1 2790259 2791328 2790349 2791263 orf19.13697|IPF20803.1|IPF17066.2|Contig4-1616_0004|orf6.5770|CA3495|CaO19.13697|RIB7|CaO19.6341 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2791240 2792542 - orf19.6340 2791240 2792542 2 2792542|2791935 2792240|2791240 2792314 2791366 orf19.13696|IPF20809.1|IPF17067.2|Contig4-1616_0003|orf6.5769|CA3494|RPB5 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2792718 2796608 - orf19.4913 2792718 2796608 1 2796608 2792718 2796467 2792838 orf19.12379|IPF22322.1|IPF15649.2|orf6.3292|CA1680|CaO19.4913|CaO19.12379|IPF15649 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 2793139 2793328 + ntar_253 2793139 2793328 1 2793139 2793328 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2797746 2798624 + orf19.4914 2797746 2798624 1 2797746 2798624 2797901 2798254 orf19.12380|IPF22319.1|IPF12676.2|Contig4-2257_0005|orf6.3293|CA1681|CaO19.12380|CaO19.4914|IPF12676 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2799719 2800493 + orf19.4914.1 2799719 2800493 1 2799719 2800493 2799928 2800161 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2800473 2802440 - orf19.4916 2800473 2802440 1 2802440 2800473 2802440 2800971 orf19.12382|IPF22260.1|IPF19926.1|Contig4-2257_0013|Contig4-2257_0014|Contig4-2257_0016|orf6.3295|CA6216|YFW2|CaO19.12382|CaO19.4916|IPF12669.3f Predicted ORF in Assemblies 19, 20 and 21; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr1 2802497 2803144 - orf19.4917 2802497 2803144 1 2803144 2802497 2803144 2802497 orf19.12383|IPF22284.1|IPF12669.2|Contig4-1725_0008|orf6.3296|CA6217|CaO19.4917|CaO19.12383|IPF12669.5f Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr1 2803638 2805337 - orf19.4918 2803638 2805337 1 2805337 2803638 2805337 2803778 orf19.12384|IPF13890.3|IPF18629.1|Contig4-2364_0002|orf6.3297|orf6.1451|CA1682|TRA98|CaO19.12384|CaO19.4918|Cirt3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 2805665 2807341 + orf19.4919 2805665 2807341 1 2805665 2807341 2805665 2806975 orf19.12385|orf19.12386|IPF19869.2|IPF18628.1|Contig4-1725_0012|orf6.3298|orf6.3299|CA1683|orf19.4920|CaO19.4919|CTN4|CaO19.12385|Cirt5|Cirt Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 2807971 2810256 + orf19.4921 2807971 2810256 1 2807971 2810256 2807971 2810142 orf19.12387|IPF13892.3|IPF6070.2|Contig4-1725_0002|Contig4-1725_0005|orf6.3300|CA1684|CaO19.4921|YFW1|CaO19.12387|IPF6070 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 2810223 2810780 - ntar_254 2810223 2810780 1 2810780 2810223 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2811829 2812406 + orf19.4921.1 2811829 2812406 1 2811829 2812406 2812003 2812167 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2812379 2813615 - orf19.4922 2812379 2813615 3 2813615|2813441|2813321 2813532|2813405|2812379 2813567 2812558 orf19.12388|IPF22281.1|IPF6076.2|Contig4-2999_0018|orf6.5902|CA3594|CaO19.4922|CaO19.12388|IPF6076|IPF6076.3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2813793 2815349 - orf19.4923 2813793 2815349 1 2815349 2813793 2815349 2813793 orf19.12389|IPF22248.1|IPF6079.1|Contig4-2999_0016|orf6.5903|CA3595|CaO19.4923|CaO19.12389|IPF6079 Predicted membrane transporter, member of the sugar porter (SP) family, major facilitator superfamily (MFS); caspofungin induced [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr1 2815474 2815686 - orf19.4923.1 2815474 2815686 1 2815686 2815474 2815686 2815474 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2815851 2819954 + orf19.4924 2815851 2819954 1 2815851 2819954 2815904 2819872 orf19.12390|IPF22318.1|IPF6085.2|Contig4-2999_0010|Contig4-2999_0011|orf6.5904|CA3596|CaO19.12390|CaO19.4924|IPF6085 Predicted ORF in Assemblies 19, 20 and 21; decreased expression observed in an ssr1 homozygous null mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=G scenario_last_exon=G] Ca21chr1 2819840 2825460 - orf19.4927 2819840 2825460 1 2825460 2819840 2825216 2820018 BNI1 orf19.12393|IPF22291.1|IPF6091.1|Contig4-2999_0009|orf6.5907|CA3597|CaO19.4927|CaO19.12393 Formin; role in cytoskeletal organization, cell polarity; role in systemic virulence in mouse; cell-cycle regulated localization to site of polarized growth, bud neck; localizes to Spitzenkorper of hyphae, minor localization at septum [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2825807 2825971 + ntar_255 2825807 2825971 1 2825807 2825971 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2827146 2829906 - orf19.4928 2827146 2829906 1 2829906 2827146 2829597 2827342 orf19.12394|IPF6094.2|IPF28177.1|Contig4-2999_0005|orf6.5908|CA3598|SEC2|CaO19.4928 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2830765 2831724 + ntar_256 2830765 2831724 1 2830765 2831724 2831135 2831299 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2831923 2835746 + orf19.4929 2831923 2835746 1 2831923 2835746 2832089 2835613 orf19.12395|IPF22332.1|IPF19785.1|Contig4-2999_0001|Contig4-2999_0002|orf6.5909|CA3599|CaO19.4929|CaO19.12395|IPF19785 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2835623 2836370 - orf19.4930 2835623 2836370 1 2836370 2835623 2836345 2835767 SPC3 orf19.12396|orf6.5910|IPF22286.1|IPF15621.2|Contig4-2611_0002|CA3600|CaO19.12396|CaO19.4930 Essential protein; similar to S. cerevisiae Spc3p, a component of the signal peptidase complex required for signal peptidase activity; predicted integral ER membrane protein; complements spc3 and suppresses sec61 S. cerevisiae mutants [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2836495 2838978 - orf19.4931 2836495 2838978 1 2838978 2836495 2838889 2836544 orf19.12397|IPF22211.1|IPF15618.2|Contig4-2611_0003|Contig4-2611_0004|orf6.5911|YNL247WA|CA3601|CaO19.12397|CaO19.4931|IPF15618 Putative tRNA-Cys synthetase; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2839066 2839572 - ntar_1425 2839066 2839572 2 2839572|2839301 2839505|2839066 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2839810 2841018 + orf19.4931.1 2839810 2841018 2 2839810|2840408 2840053|2841018 2839943 2840692 RPL14 IPF22199.1|IPF12937.2|Contig4-2611_0007|CA3602|RPL14B|RPL14B.3 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2840990 2843481 - orf19.4932 2840990 2843481 1 2843481 2840990 2843438 2841153 orf19.12398|IPF22213.1|IPF12940.2|Contig4-2611_0010|orf6.5912|CA3603|MEF1|CaO19.12398|CaO19.4932 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2843627 2845071 - orf19.4933 2843627 2845071 1 2845071 2843627 2845037 2843736 FAD3 orf19.12399|IPF22268.1|IPF12942.2|Contig4-2611_0011|orf6.5913|CA3604|CaO19.12399|ODE2|CaO19.4933|IPF12942 Omega-3 fatty acid desaturase, involved in production of alpha-linolenic acid, which is a major component of membranes; caspofungin induced; Plc1p-regulated; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2848585 2850423 + orf19.4934 2848585 2850423 1 2848585 2850423 2848705 2849916 OP4 orf19.12400|IPF17845.2|IPF15453.1|Contig4-2962_0020|orf6.5914|orf6.6056|OPS4|CA3713|CaO19.4934 Ala- Leu- and Ser-rich protein; N-terminal hydrophobic region; possible glycosylation; gene is transcribed specifically in opaque-phase cells, repressed by alpha pheromone in opaque MTLa homozygotes [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2853604 2853999 + orf19.4936 2853604 2853999 1 2853604 2853999 2853604 2853999 orf19.12402|IPF22293.1|IPF7891.2|Contig4-2962_0015|orf6.6054|CA3712|CaO19.4936|CaO19.12402|IPF7891 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2855099 2855375 + orf19.4936.1 2855099 2855375 1 2855099 2855375 2855099 2855314 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 2855537 2855791 + ntar_257 2855537 2855791 1 2855537 2855791 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2856255 2860412 - orf19.4937 2856255 2860412 1 2860412 2856255 2859992 2856351 CHS3 orf19.12403|orf19.12404|IPF22336.1|IPF22321.1|IPF7889.2|IPF7886.2|Contig4-2962_0013|orf6.6053|orf6.6052|CHS3.3f|CHS3.5f|CA3711|CA3710|orf19.4938 Major chitin synthase of yeast-form and hyphal cells; synthesizes short-chitin fibrils; Chs4p-activated; transcription induced at yeast-hyphal transition; Chs1p and Chs2p, but not Chs3p, are inhibited by the protoberberine HWY-289 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2861144 2866365 - orf19.4939 2861144 2866365 1 2866365 2861144 2866254 2861350 orf19.12405|IPF22294.1|IPF7880.2|Contig4-2962_0004|Contig4-2962_0005|Contig4-2962_0008|orf6.6051|CA3709|CaO19.4939|MON2|CaO19.12405|IPF7880 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2866591 2868635 - orf19.4940 2866591 2868635 1 2868635 2866591 2868423 2866744 orf19.12406|IPF22247.1|IPF7876.2|Contig4-2962_0002|orf6.6050|HIP1|CA3708|CaO19.4940|CaO19.12406 Putative histidine permease; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2868870 2869912 - orf19.4941 2868870 2869912 1 2869912 2868870 2869829 2869020 TYE7 orf19.12407|IPF22280.1|IPF5663.1|Contig4-2994_0001|orf6.6049|CA3707|CaO19.12407|CaO19.4941 Transcription factor with bHLH (basic region, helix-loop-helix) motif involved in control of glycolysis; hyphally regulated via Cph1p, Cyr1p; flucytosine, Hog1p induced; amphotericin B, caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2871070 2872104 + orf19.4942 2871070 2872104 1 2871070 2872104 2871337 2871705 orf19.12408|IPF22323.1|IPF28213.1|Contig4-2994_0003|orf6.6048|CaO19.12408|CaO19.4942 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr1 2874278 2875711 + orf19.4943 2874278 2875711 1 2874278 2875711 2874278 2875654 PSA2 orf19.12409|PSA1|IPF22264.1|IPF5668.1|Contig4-2994_0010|orf6.6047|CA3706|CaO19.12409|CaO19.4943 Predicted ORF in Assemblies 19, 20 and 21; macrophage-downregulated gene; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 2875601 2879416 - orf19.4945 2875601 2879416 1 2879416 2875601 2879371 2875727 MSH6 orf19.12411|IPF22327.1|IPF5670.1|Contig4-2994_0011|orf6.6045|CA3705|CaO19.12411|CaO19.4945 Protein similar to S. cerevisiae Msh6p, which is involved in mismatch repair; repressed under Cdc5p depletion [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2879648 2880409 + orf19.4946 2879648 2880409 1 2879648 2880409 2879648 2880409 orf19.12412|IPF22282.1|IPF5671.2|Contig4-2994_0014|orf6.6044|CA3704|CaO19.4946|CaO19.12412|IPF5671 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2879949 2880166 - ntar_258 2879949 2880166 1 2880166 2879949 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2880569 2881410 + orf19.4947 2880569 2881410 1 2880569 2881410 2880732 2881241 IPF18761.2|IPF5672.2|Contig4-2994_0015|orf6.6043|CA1104|CaO19.4947|IPF18761|IPF18761.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2881235 2882794 - orf19.4948 2881235 2882794 1 2882794 2881235 2882679 2881465 orf19.12413|IPF5673.2|IPF28194.1|Contig4-2994_0016|orf6.2434|orf6.6042|CA1103|REX3|CaO19.4948|IPF5673 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2883066 2883368 - orf19.4949 2883066 2883368 1 2883368 2883066 2883368 2883066 IPF28234.1|orf6.6041|CaO19.4949 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2883397 2883771 + ntar_259 2883397 2883771 1 2883397 2883771 2883397 2883615 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2883750 2886365 - orf19.4950 2883750 2886365 1 2886365 2883750 2886263 2883822 AKR1 orf19.12414|IPF22207.1|IPF5675.1|Contig4-2994_0019|orf6.2433|CA1102|CaO19.4950|CaO19.12414 Ankyrin-repeat protein; increased transcription is observed upon fluphenazine treatment [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2887636 2889563 + orf19.4951 2887636 2889563 1 2887636 2889563 2888158 2889426 orf19.12415|IPF5678.1|IPF28195.1|Contig4-2994_0024|orf6.2432|CA1101|CaO19.4951|IPF5678 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2891054 2893171 + orf19.4952 2891054 2893171 1 2891054 2893171 2891695 2892633 orf19.12417|IPF5681.2|IPF19696.1|Contig4-1718_0002|orf6.1485|orf6.2430|CA1100|CaO19.4952|IPF5681 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2893362 2894169 + orf19.4952.1 2893362 2894169 2 2893362|2893647 2893539|2894169 2893446 2894008 IPF22326.1|IPF13976.2|Contig4-2314_0003 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2894251 2895373 + orf19.4953 2894251 2895373 1 2894251 2895373 2894367 2895263 orf19.12418|IPF19466.2|IPF13975.2|Contig4-2314_0004|orf6.1486|orf6.44|CA0511|CaO19.4953|IPF13975 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2895226 2896307 - orf19.4954 2895226 2896307 1 2896307 2895226 2896155 2895565 orf19.12419|IPF19467.1|IPF13974.2|Contig4-2314_0005|orf6.1487|orf6.43|CA0512|CaO19.4954|PPA1|VMA16 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2896460 2896690 + ntar_260 2896460 2896690 1 2896460 2896690 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2896806 2898392 + orf19.4955 2896806 2898392 2 2896806|2896939 2896878|2898392 2896806 2898392 orf19.12420|IPF22262.1|IPF13972.2|Contig4-3096_0020|orf6.1488|CA0513|SPS2|CaO19.4955|IPF13972 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=E] Ca21chr1 2898330 2901591 - orf19.4956 2898330 2901591 1 2901591 2898330 2901442 2898458 RPN1 orf19.12421|IPF9623.2|IPF19458.2|Contig4-1464_0001|Contig4-1464_0002|Contig4-2724_0012|orf6.2660|orf6.52|CA1252|CaO19.4956 Predicted ORF in Assemblies 19, 20 and 21; regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2901750 2901977 + ntar_261 2901750 2901977 1 2901750 2901977 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2902432 2904676 + orf19.4958 2902432 2904676 1 2902432 2904676 2902728 2904596 ECM25 orf19.12423|IPF9624.2|IPF19459.2|Contig4-2724_0008|orf6.2658|CA6293|IPF9624.3f Non-essential protein involved in cell morphogenesis; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 2904704 2906833 - orf19.4959 2904704 2906833 1 2906833 2904704 2906720 2904999 orf19.12424|IPF9626.1|IPF28186.1|Contig4-2724_0007|orf6.2657|CA1250|CaO19.4959|IPF9626 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2907188 2908570 - orf19.4960 2907188 2908570 1 2908570 2907188 2908446 2907412 orf19.12425|IPF22274.1|IPF9628.2|Contig4-2724_0004|orf6.2656|CA1249|CaO19.12425|SPE4|CaO19.4960 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2909166 2909770 - ntar_262 2909166 2909770 1 2909770 2909166 2909537 2909394 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2911515 2913771 + orf19.4961 2911515 2913771 1 2911515 2913771 2911732 2913486 STP2 orf19.12426|IPF22239.1|IPF15844.2|Contig4-1523_0002|orf6.2844|CA1372|CaO19.4961|CaO19.12426|IPF15844 Transcription factor; activates transcription of genes encoding amino acid permeases; activated via amino-acid-induced proteolytic processing (Ssy1p and Csh3p dependent); also amino-acid-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2913658 2914912 - orf19.4962 2913658 2914912 1 2914912 2913658 2914912 2913785 orf19.12427|IPF22269.1|IPF19731.1|Contig4-1523_0004|Contig4-2827_0019|orf6.2843|CA1371|CaO19.12427|CaO19.4962|IPF19731 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 2915065 2916340 + orf19.4963 2915065 2916340 1 2915065 2916340 2915143 2916339 orf19.12428|IPF22271.1|IPF15966.2|Contig4-1682_0003|orf6.2842|CA1370|CaO19.4963|TCI1|CaO19.12428 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2916144 2916334 - ntar_263 2916144 2916334 1 2916334 2916144 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2916541 2917612 + orf19.4964 2916541 2917612 1 2916541 2917612 2916611 2917456 orf19.12429|IPF22279.1|IPF15968.2|Contig4-1682_0001|orf6.2841|CA1369|CaO19.12429|CaO19.4964|IPF15968 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2917666 2919850 + orf19.4965 2917666 2919850 1 2917666 2919850 2917715 2919805 orf19.12430|IPF22223.1|IPF15969.2|orf6.2840|CA1368|CaO19.4965|CaO19.12430|IPF15969 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 2919892 2922610 - orf19.4966 2919892 2922610 1 2922610 2919892 2922382 2920187 orf19.12431|IPF16755|IPF22217.1|IPF16755.2|Contig4-2421_0001|orf6.2839|YPR021C|CA1367|AGC1|CaO19.4966|CaO19.12431 Protein not essential for viability; transcription is alkaline upregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2925482 2926164 + orf19.4967 2925482 2926164 2 2925482|2925638 2925567|2926164 2925549 2926017 COX19 orf19.12432|IPF13215.1|IPF17679.1|Contig4-2421_0006|orf6.1897|orf6.2838|CA0768|CaO19.4967 Predicted ORF in Assemblies 19, 20 and 21; Plc1p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2926044 2931142 - orf19.4969 2926044 2931142 2 2931142|2930711 2930784|2926044 2930787 2926204 KEM1 orf19.12434|XRN1|IPF13214.2|IPF28204.1|Contig4-2907_0019|orf6.2836|orf6.1895|KEM1.3|CA0767|CaO19.4969 5'-->3' exoribonuclease; required for wild-type filamentous growth; not essential for viability; functionally complements S. cerevisiae kem1 mutant slow growth & mating and partially complements invasive growth & pseudohyphal growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2932190 2933917 - orf19.4970 2932190 2933917 1 2933917 2932190 2933917 2932190 orf19.12435|IPF15335.2|IPF28185.1|Contig4-2387_0004|orf6.180|orf6.1894|CA0766|CaO19.4970|IPF15335 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2935076 2938628 - orf19.4972 2935076 2938628 1 2938628 2935076 2937571 2935625 orf19.12437|IPF7964.2|IPF15920.1|Contig4-2387_0006|orf6.1556|orf6.1893|orf6.3141|CA0556|CaO19.4972|IPF15920 Putative transcription factor with zinc finger DNA-binding motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2944456 2947553 + orf19.4975 2944456 2947553 1 2944456 2947553 2944794 2947553 HYR1 orf19.12440|Contig4-2860_0006|GPX1|IPF19734.1|IPF19516.2|orf6.3143|orf6.857|CA1576|CaO19.4975|CA0557|HYR1.53|IPF7957.2 Nonessential, GPI anchored, predicted cell wall protein; macrophage-induced protein; induced in hyphae; induction associated with azole resistance; regulated by Rfg1p, Efg1p, Nrg1p, Tup1p, Cyr1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chr1 2951250 2951606 + orf19.4976 2951250 2951606 1 2951250 2951606 2951250 2951606 orf19.12443|IPF22315.1|IPF28200.1|orf6.3146|orf6.858|CaO19.4976 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2952187 2954246 + orf19.4979 2952187 2954246 1 2952187 2954246 2952225 2954225 KNS1 orf19.12446|IPF11410.2|IPF28178.1|Contig4-2706_0013|orf6.3149|CA1577|CaO19.4979|CaO19.12446 Protein not essential for viability; similar to S. cerevisiae Kns1p, which is a protein kinase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 2955674 2957947 + orf19.4980 2955674 2957947 1 2955674 2957947 2955762 2957732 HSP70 orf19.12447|HS71|SSA1|IPF22233.1|IPF11819.2|SSA4|Contig4-2251_0001|CA1230|CaO19.4980|CaO19.12447|orf6.2627 Putative hsp70 chaperone; role in sensitivity to beta-defensins; heat-shock, amphotericin B, Cd, ketoconazole-induced; farnesol-downregulated in biofilm; farnesol-induced; surface localized in yeast-form and hyphal cells; antigenic in host [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2957899 2960767 - orf19.4981 2957899 2960767 1 2960767 2957899 2960132 2958018 orf19.12448|IPF22224.1|IPF11817.2|Contig4-2251_0004|orf6.2628|CA1231|CaO19.4981|CaO19.12448|IPF11817 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2960986 2962844 - orf19.4982 2960986 2962844 1 2962844 2960986 2962728 2961100 orf19.12449|IPF22252.1|IPF11815.2|Contig4-2494_0015|orf6.2629|CA1232|CaO19.12449|TGL99|CaO19.4982|IPF11815 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2963219 2964292 - orf19.4983 2963219 2964292 1 2964292 2963219 2964210 2963395 orf19.12450|IPF1758.2|IPF11814.1|Contig4-2494_0009|orf6.2630|orf6.8026|CA1233|CaO19.4983|IPF11814 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2964351 2966422 + orf19.4984 2964351 2966422 1 2964351 2966422 2964525 2966081 orf19.12451|IPF1760.2|IPF22206.1|IPF19907.2|IPF18120.1|Contig4-2494_0006|orf6.2631|orf6.8025|CA5275|IPF1760.3f|CA5276|IPF1759.53f|IPF1759.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2966582 2968760 + orf19.4985 2966582 2968760 1 2966582 2968760 2966690 2968444 GUP1 orf19.12452|IPF22244.1|IPF1764.2|Contig4-2494_0003|orf6.8024|CA5274|CaO19.4985|CaO19.12452|IPF1764 Protein with role in glycerol uptake; functionally complements growth of S. cerevisiae gup1 mutant under salt stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2968520 2969961 - orf19.4987 2968520 2969961 1 2969961 2968520 2969909 2968560 NUP49 orf19.12454|IPF22266.1|IPF1766.2|Contig4-2494_0001|orf6.8022|CA5273|CaO19.4987|CaO19.12454 Nuclear pore protein [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2970007 2971788 + orf19.4988 2970007 2971788 1 2970007 2971788 2970121 2971638 orf19.12455|IPF22259.1|IPF1770.1|Contig4-3025_0024|orf6.8021|CA5272|CaO19.4988|CaO19.12455|IPF1770 Predicted ORF in Assemblies 19, 20 and 21; greater mRNA abundance observed in a cyr1 homozygous null mutant than in wild type [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2972831 2973662 + ntar_264 2972831 2973662 1 2972831 2973662 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2975072 2975301 + ntar_265 2975072 2975301 1 2975072 2975301 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2976102 2979816 + orf19.4991 2976102 2979816 1 2976102 2979816 2976356 2979172 MPT5 orf19.12458|IPF22202.1|IPF1777.1|Contig4-3025_0018|Contig4-3025_0020|orf6.8018|CA5271|CaO19.4991|CaO19.12458|IPF1777 Protein induced during the mating process [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 2981440 2984060 + orf19.4993 2981440 2984060 1 2981440 2984060 2981615 2984005 SEC18 orf19.12460|orf19.12461|IPF22276.1|IPF22225.1|IPF22267.1|IPF1784.2|IPF1785.2|IPF1786.2|Contig4-3025_0011|Contig4-3025_0012|Contig4-3025_0013|orf6.8016|orf6.8015|CA5270|CA5268|orf19.4994|SEC18.5f Functional homolog of S. cerevisiae Sec18p, which acts in protein transport; conserved ATP binding site; not glycosylated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2985121 2986353 + orf19.4995 2985121 2986353 1 2985121 2986353 2985121 2986353 orf19.12462|IPF22270.1|IPF1787.1|Contig4-3025_0010|orf6.8014|CA5267|CaO19.12462|CaO19.4995|IPF1787.5f Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 2986453 2987427 + orf19.4996 2986453 2987427 1 2986453 2987427 2986453 2987349 orf19.12463|IPF22278.1|IPF1789.1|Contig4-3025_0009|orf6.8013|CA5266|CaO19.4996|CaO19.12463|IPF1787.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 2987591 2990214 - orf19.4997 2987591 2990214 1 2990214 2987591 2990032 2987795 KIS2 orf19.12464|IPF22214.1|IPF1792.1|Contig4-3025_0006|Contig4-3025_0007|orf6.8012|CA5265|CaO19.4997|CaO19.12464|IPF1792 Scaffold protein of Snf1p complex; similar to S. cerevisiae Gal83p and Sip2p; interacts with Snf4p; interaction with Snf1p complex is regulated by carbon source, decreased on ethanol; N-terminal myristoylation; Hog1p-downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2990653 2990797 + ntar_266 2990653 2990797 1 2990653 2990797 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2991018 2991235 + ntar_267 2991018 2991235 1 2991018 2991235 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2993085 2996480 + orf19.4998 2993085 2996480 2 2993085|2993461 2993394|2996480 2993348 2996389 orf19.12465|IPF22198.1|IPF1798.2|orf6.8011|CA5264|CaO19.4998|CHA4|CaO19.12465|IPF1798 Predicted ORF in Assemblies 19, 20 and 21; caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 2997027 2999019 + orf19.5000 2997027 2999019 1 2997027 2999019 2997207 2998889 CYB2 orf19.12467|orf6.8009|IPF22249.1|IPF1801.1|CYB3|Contig4-3061_0027|CA5263|CaO19.12467|CaO19.5000 Protein described as precursor protein of cytochrome b2; transcriptionally regulated by iron; expression greater in high iron; alkaline downregulated; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 2999251 2999602 - ntar_268 2999251 2999602 1 2999602 2999251 2999576 2999430 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 2999788 3001737 + orf19.5001 2999788 3001737 1 2999788 3001737 2999889 3001664 CUP2 orf19.12468|IPF22242.1|IPF1804.1|Contig4-3061_0022|Contig4-3061_0024|orf6.8008|CA5262|CaO19.5001|HAA1|CaO19.12468|IPF1804 Protein not essential for viability; similar to S. cerevisiae Cup2p, which is a copper-binding transcription factor that activates transcription of metallothionein genes [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3001619 3003232 - orf19.5003 3001619 3003232 1 3003232 3001619 3003092 3001746 orf19.12470|IPF22265.1|IPF1805.2|Contig4-3061_0021|orf6.8006|CA5261|CaO19.5003|CaO19.12470|IPF1805 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3003325 3006105 + orf19.5004 3003325 3006105 1 3003325 3006105 3003486 3006032 RAD54 orf19.12471|IPF22209.1|IPF1807.1|Contig4-3061_0018|orf6.8005|CA5260|CaO19.5004|CaO19.12471 Protein similar to S. cerevisiae Rad54p, which is a DNA-dependent ATPase involved in DNA repair; induced under hydroxyurea treatment [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3005487 3006102 - ntar_269 3005487 3006102 1 3006102 3005487 3005942 3005802 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 3006313 3008456 + orf19.5005 3006313 3008456 1 3006313 3008456 3006473 3008419 OSM2 orf19.12472|IPF22234.1|IPF1808.1|Contig4-3061_0016|orf6.8004|CA5259|CaO19.12472|OSM1|CaO19.5005 Protein described as mitochondrial fumarate reductase; regulated by Ssn6p, Gcn2p, and Gcn4p; Hog1p-downregulated; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3008348 3009103 - orf19.5006 3008348 3009103 1 3009103 3008348 3009024 3008491 GCV3 orf19.12473|IPF22289.1|IPF1809.1|Contig4-3061_0015|orf6.8003|CA5258|CaO19.5006|CaO19.12473 Predicted ORF in Assemblies 19, 20 and 21; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3009300 3010365 - orf19.5006.1 3009300 3010365 2 3010365|3009851 3009924|3009300 3010010 3009603 IPF22222.1|Contig4-3061_0014|CA5256|orf19.5006.2|SNC2|CA5257|SNC2.exon2|IPF1811.1 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 3011392 3013534 + orf19.5007 3011392 3013534 2 3011392|3012132 3011473|3013534 3011464 3013252 ACT1 orf19.12474|ACT|IPF22272.1|IPF1819.1|Contig4-3061_0012|orf6.8002|CA5255 Actin; gene has intron; transcriptionally regulated by growth phase and by starvation; localizes to polarized growth site in budding and hyphal cells; required for wild-type Cdc42p localization; unprocessed N terminus [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 3013367 3014001 - orf19.5008.1 3013367 3014001 1 3014001 3013367 3013825 3013526 IPF22290.1|IPF1820.1|Contig4-3061_0011|CA5254|IPF1820 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3014055 3016087 + orf19.5009 3014055 3016087 1 3014055 3016087 3014085 3016001 orf19.12476|IPF22235.1|IPF1821.1|Contig4-3061_0010|orf6.8000|CA5253|CaO19.5009|KEL3|CaO19.12476 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3015947 3017167 - orf19.5010 3015947 3017167 1 3017167 3015947 3017083 3016103 DIM1 orf19.12477|IPF22277.1|IPF1822.1|Contig4-3061_0009|orf6.7999|CA5252|CaO19.5010|CaO19.12477 Protein likely to be essential for growth, based on an insertional mutagenesis strategy; similar to S. cerevisiae Dim1p, which is an 18S rRNA dimethylase involved in rRNA modification and processing; induced upon biofilm formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3017721 3020279 + orf19.5011 3017721 3020279 1 3017721 3020279 3017916 3020192 KAR9 orf19.12478|IPF22215.1|IPF1824.1|Contig4-3061_0004|Contig4-3061_0005|Contig4-3061_0006|orf6.7998|CA5251|CaO19.5011|CaO19.12478|IPF1824 Protein similar to S. cerevisiae Kar9p, which has role in mitotic spindle positioning; nonessential; localizes to bud tip, bud neck, hyphal tip; wild-type localization requires actin and microtubule cytoskeleton; induced by alpha factor [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3019663 3020883 - orf19.5012 3019663 3020883 1 3020883 3019663 3020879 3020283 orf19.12479|IPF22285.1|IPF1826.2|Contig4-3061_0003|orf6.7997|CA5250|CaO19.5012|CaO19.12479|IPF1826 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3021026 3022798 + orf19.5013 3021026 3022798 1 3021026 3022798 3021071 3022705 AGM1 orf19.12480|IPF22253.1|IPF1827.2|Contig4-3061_0002|orf6.7996|CA5249|PCM1|CaO19.5013|CaO19.12480 Phosphoacetylglucosamine mutase (N-acetylglucosamine-phosphate mutase); enzyme of UDP-N-acetylglucosamine (UDP-GlcNAc) biosynthesis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3022296 3023568 - orf19.5014 3022296 3023568 1 3023568 3022296 3023536 3022829 orf19.12481|IPF22283.1|IPF1828.1|Contig4-3061_0001|orf6.7995|CA5248|CaO19.12481|CaO19.5014|IPF1828 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3025427 3031015 + orf19.5015 3025427 3031015 1 3025427 3031015 3026140 3030825 MYO2 orf19.12482|IPF22298.1|IPF13531.2|Contig4-2345_0002|Contig4-2345_0004|orf6.7994|CA5247|CaO19.5015|CaO19.12482 Class V myosin; nonessential; required for wild-type actin cytoskeletal polarity, nuclear organization and migration, and hyphal growth; sole class V myosin in C. albicans; conserved myosin ATPase and tail domains [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3030836 3031451 - orf19.5016 3030836 3031451 1 3031451 3030836 3031406 3031041 orf19.12483|IPF19808|IPF22314.1|IPF19808.1|Contig4-2345_0001|orf6.7993|CA5246|CaO19.12483|CaO19.5016 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3031584 3033599 - orf19.5017 3031584 3033599 1 3033599 3031584 3033599 3031584 orf19.12484|IPF22231.1|IPF3048.2|Contig4-3075_0002|orf6.7992|CA5245|DUR32|CaO19.12484|CaO19.5017 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 3032213 3032718 + ntar_270 3032213 3032718 1 3032213 3032718 3032446 3032622 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 3033240 3033450 + ntar_271 3033240 3033450 1 3033240 3033450 3033240 3033362 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 3035108 3037466 + orf19.5019 3035108 3037466 1 3035108 3037466 3035261 3037345 orf19.12486|IPF22226.1|IPF3043.1|Contig4-3075_0004|orf6.7990|CA5244|CaO19.5019|CaO19.12486|IPF3043 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3035482 3035670 - ntar_272 3035482 3035670 1 3035670 3035482 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 3037401 3038743 - orf19.5020 3037401 3038743 1 3038743 3037401 3038662 3037640 orf19.12487|IPF22275.1|IPF3040.1|Contig4-3075_0006|orf6.7989|CA5243|CaO19.5020|CaO19.12487|IPF3040 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 3038875 3040408 - orf19.5021 3038875 3040408 1 3040408 3038875 3040358 3039105 PDX1 orf19.12488|IPF22263.1|IPF3038.1|Contig4-3075_0007|orf6.7988|CA5242|CaO19.12488|CaO19.5021 Pyruvate dehydrogenase complex protein X, an essential component of the mitochondrial pyruvate dehydrogenase complex which is involved in the respiratory pathway; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 3041021 3043659 + orf19.5022 3041021 3043659 1 3041021 3043659 3041533 3043548 orf19.12489|IPF22229.1|IPF3034.1|SMF2|Contig4-3075_0009|orf6.7987|CA5241|CaO19.12489|CaO19.5022|SMF3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3043640 3045169 - orf19.5023 3043640 3045169 1 3045169 3043640 3045169 3043640 DAL7 orf19.12490|IPF3032|IPF22258.1|IPF3032.1|Contig4-3075_0010|orf6.7986|CA5240|CaO19.5023|CaO19.12490 Putative allantoate permease; fungal-specific (no human or murine homolog); not essential for viability [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 3045802 3048283 - orf19.5024 3045802 3048283 2 3048283|3047465 3048166|3045802 3048182 3045995 GND1 orf19.12491|IPF22257.1|IPF3028.2|Contig4-3075_0013|orf6.7985|CA5239|CaO19.5024|DOR14|CaO19.12491 Putative 6-phosphogluconate dehydrogenase; soluble protein in hyphae; farnesol-, macrophage-induced protein; antigenic in mouse; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 3049142 3049811 + ntar_273 3049142 3049811 1 3049142 3049811 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 3051442 3053373 + orf19.5025 3051442 3053373 1 3051442 3053373 3051624 3053207 MET3 orf19.12492|orf6.7984|IPF22255.1|IPF3022.1|Contig4-3075_0019|Contig4-3075_0020|CA5238|CaO19.5025|CaO19.12492 Putative ATP sulfurlyase of sulfate assimilation; repressed by Met or Cys, Sfu1p, or in fluconazole-resistant isolate; strongly induced on biofilm formation, even in presence of Met and Cys; Hog1p-, caspofungin-, possibly adherence-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3053446 3057630 - orf19.5026 3053446 3057630 1 3057630 3053446 3057052 3053519 orf19.12493|IPF22331.1|IPF3021.1|Contig4-3075_0021|orf6.7983|CA5237|CaO19.5026|CaO19.12493|ZMS1 Putative transcription factor with zinc finger DNA-binding motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3057469 3058059 + ntar_274 3057469 3058059 1 3057469 3058059 3057811 3057981 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 3060993 3061113 - ntar_275 3060993 3061113 1 3061113 3060993 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 3061122 3061194 - ta(agc)7 3061122 3061194 1 3061194 3061122 tA(AGC)7.2 tRNA-Ala predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 3061366 3063562 - orf19.5027 3061366 3063562 1 3063562 3061366 3063251 3061542 LCB2 orf19.12494|IPF22245.1|IPF3017.1|Contig4-3075_0027|orf6.7982|CA5236|CaO19.5027|CaO19.12494 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to aureobasidin A [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 3063852 3065578 - orf19.5029 3063852 3065578 1 3065578 3063852 3065571 3063934 MODF orf19.12496|IPF22250.1|IPF3015.1|Contig4-3075_0031|orf6.7980|CA5235|CaO19.5029|CaO19.12496|IPF3015 Predicted ORF in Assemblies 19, 20 and 21; ABC family protein; similar to E. coli ModF/PhrA protein, which may have a role in molybdate metabolism; no human or murine homolog [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 3065742 3065876 - ntar_276 3065742 3065876 1 3065876 3065742 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 3065917 3067270 + orf19.5030 3065917 3067270 1 3065917 3067270 3066059 3067138 orf19.12497|IPF18123.2|IPF3014.1|Contig4-3075_0032|orf6.7979|CA5234|CaO19.5030|CaO19.12497|IPF3014 Predicted ORF in Assemblies 19, 20 and 21; induced during planktonic growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3067493 3069954 + orf19.5031 3067493 3069954 1 3067493 3069954 3067600 3069624 SSK1 orf19.12498|orf6.7978|IPF22230.1|IPF3012.2|CA5233|CaO19.12498|CaO19.5031 Response regulator of two-component system; role in oxidative stress response, cell wall biosynthesis, virulence, hyphal growth on solid media; expressed in hyphae and yeast-form cells; putative peroxisomal targeting sequence (PTS1) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3073023 3073272 + ntar_277 3073023 3073272 1 3073023 3073272 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 3074049 3075708 + orf19.5032 3074049 3075708 1 3074049 3075708 3074225 3075343 SIM1 orf19.12499|IPF22273.1|IPF10421.1|Contig4-2686_0006|orf6.7977|SUN42|CA5232|CaO19.5032|UTH1|CaO19.12499 Protein involved in cell wall maintenance, redundant with Sun41p; described as a DNA replication regulator; produced under vaginal conditions; macrophage-downregulated gene; transcription is negatively regulated by Rim101p, Cyr1p, Ras1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3075613 3076466 - orf19.5033 3075613 3076466 1 3076466 3075613 3076326 3075832 orf19.12500|IPF22292.1|IPF10422.1|Contig4-2686_0005|orf6.7976|CA5231|ATG12|CaO19.12500|CaO19.5033|IPF10422 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3076610 3078822 + orf19.5034 3076610 3078822 1 3076610 3078822 3076673 3078670 orf19.12501|IPF22219.1|IPF10424.1|Contig4-2686_0004|orf6.7975|CA5230|YBP1|CaO19.12501|CaO19.5034|IPF10424 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3078610 3080586 - orf19.5035 3078610 3080586 1 3080586 3078610 3080366 3078708 orf19.12502|IPF22251.1|IPF10425.1|Contig4-2686_0002|orf6.7974|CA5229|HPC2|CaO19.5035|CaO19.12502|IPF10425 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3080876 3083648 - orf19.7205 3080876 3083648 1 3083648 3080876 3083072 3081048 DUR7 IPF901.1|Contig4-3075_0002|CA5331|DUR33.5eoc|DUR33|orf6.8105 Putative urea transporter; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 3083753 3084576 + orf19.7206 3083753 3084576 1 3083753 3084576 3083829 3084437 OCA6 IPF900.2|Contig4-3017_0006|orf6.8106|CA5332|CaO19.7206|IPF900.3f|IPF900.3 Putative protein phosphatase of the PTP family (tyrosine-specific), similar to S. cerevisiae Oca6p; mutant shows virulence defect [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3084346 3086905 - orf19.7207 3084346 3086905 1 3086905 3084346 3086875 3084440 DOA4 IPF899.1|Contig4-3017_0010|orf6.8107|CA5333|CaO19.7207 Protein not essential for viability; similar to S. cerevisiae Doa4p, which is ubiquitin hydrolase, involved in recycling ubiquitin from proteasome-bound ubiquitinated intermediates; oxidative stress-induced via Cap1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3087751 3088943 + orf19.7208 3087751 3088943 2 3087751|3088101 3088032|3088943 3087751 3088943 CSK1 SMK1|IPF895.1|Contig4-3017_0013|orf6.8108|CA5334 [NOT TRANSCRIBED?] Putative mitogen-activated protein (MAP) kinase with an unknown role; null mutant produces wrinkled colonies; similar to S. cerevisiae Smk1p, which is a protein kinase required for sporulation [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 3089336 3089743 + orf19.7209 3089336 3089743 1 3089336 3089743 3089336 3089743 IPF894.1|Contig4-3017_0014|orf6.8109|CA5335|CaO19.7209|IPF894 Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide in yhb1 mutant [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 3089974 3091090 + orf19.7210 3089974 3091090 1 3089974 3091090 3090053 3091060 IPF893.1|Contig4-3017_0016|orf6.8110|CA5336|CaO19.7210|IPF893 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 3091220 3093651 + orf19.7212 3091220 3093651 1 3091220 3093651 3091220 3093523 IPF891.1|Contig4-3017_0017|orf6.8112|CA5337|CaO19.7212|APL1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 3093485 3096946 - orf19.7213 3093485 3096946 1 3096946 3093485 3096896 3093525 IPF889.2|Contig4-3017_0019|Contig4-3017_0020|orf6.8113|CA5338|CaO19.7213|IPF889 Putative ATP-dependent RNA helicase; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3097085 3098991 + orf19.7214 3097085 3098991 1 3097085 3098991 3097299 3098807 IPF885.1|Contig4-3017_0021|orf6.8114|CA5339|CaO19.7214|IPF885 Similar to glucan 1,3-beta-glucosidase; regulated by Nrg1p, Tup1p; possibly regulated by Tac1p; induced upon biofilm formation; induced by nitric oxide; induced during cell wall regeneration; detected by mass spec in stationary phase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3099386 3104927 + orf19.7215 3099386 3104927 1 3099386 3104927 3099412 3104868 IPF883.1|Contig4-3017_0022|orf6.8115|CA5340|CaO19.7215|IPF883 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3105046 3105567 + orf19.7215.3 3105046 3105567 2 3105046|3105159 3105097|3105567 3105095 3105476 IPF878.1|Contig4-2519_0001|CA5341|HSP10|HSP10.3 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 3105779 3106769 + orf19.7216 3105779 3106769 1 3105779 3106769 3105892 3106557 IPF877.1|Contig4-2519_0002|orf6.8116|CA5342|YPT521|CaO19.7216 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3106740 3107884 - orf19.7217 3106740 3107884 1 3107884 3106740 3107870 3106779 RPL4B IPF875.1|Contig4-2519_0003|orf6.8117|CA5343|RPL4|CaO19.7217 Putative ribosomal protein; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3108053 3109128 - orf19.7218 3108053 3109128 1 3109128 3108053 3109061 3108246 RBE1 PRY2|IPF872.1|Contig4-2519_0004|orf6.8118|CA5344|CaO19.7218 Putative cell wall protein; transcription is negatively regulated by Rim101p, Efg1p, Ssn6p; alkaline downregulated; predicted signal sequence, O-glycosylation; no GPI anchor predicted [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3112465 3113343 + ntar_278 3112465 3113343 1 3112465 3113343 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 3113471 3115478 + orf19.7219 3113471 3115478 1 3113471 3115478 3113806 3114951 FTR1 orf6.8119|IPF868.1|Contig4-3043_0004|CA5345|CaO19.7219 High-affinity iron permease (ferric citrate, ferrioxamines E or B, transferrin); required for mouse virulence, low-iron growth; iron, amphotericin B, caspofungin, ciclopirox, Hog1p regulated; complements S. cerevisiae ftr1 iron transport [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3115434 3118996 - orf19.7221 3115434 3118996 1 3118996 3115434 3118760 3115551 SET3 IPF867.2|Contig4-3043_0006|Contig4-3043_0007|orf6.8121|CA5346|CaO19.7221|IPF867 Protein similar to S. cerevisiae Set3p, which is an NAD-dependent histone deacetylase; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3119409 3120054 + ntar_279 3119409 3120054 1 3119409 3120054 3119583 3119759 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 3119723 3120873 - orf19.7222 3119723 3120873 1 3120873 3119723 3120326 3119961 PAM16 IPF864.1|Contig4-3043_0009|orf6.8122|CA5347|CaO19.7222|IPF864 Protein described as similar to maltase; regulated by Gcn4p; repressed in response to amino acid starvation (3-aminotriazole treatment) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3121116 3123015 + orf19.7223 3121116 3123015 1 3121116 3123015 3121139 3122893 IPF863.1|Contig4-3043_0010|orf6.8123|CA5348|CaO19.7223|IPF863 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3123185 3125088 + orf19.7224 3123185 3125088 1 3123185 3125088 3123255 3124931 IPF861.1|Contig4-3043_0014|orf6.8124|CA5349|CaO19.7224|IPF861 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3125467 3127099 + orf19.7225 3125467 3127099 1 3125467 3127099 3125467 3127038 IPF859.1|Contig4-3043_0016|orf6.8125|CA5350|CaO19.7225|IPF859 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr1 3127013 3127472 - orf19.7227 3127013 3127472 1 3127472 3127013 3127472 3127098 IPF857.1|Contig4-3043_0017|orf6.8127|CA5351|CaO19.7227|YPI1|IPF857 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to toxic ergosterol analog [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 3127776 3128918 + orf19.7228 3127776 3128918 1 3127776 3128918 3127809 3128801 IPF856.1|Contig4-3043_0018|orf6.8128|CA5352|CaO19.7228|IPF856 Putative protein of unknown function, transcription is positively regulated by Tbf1p; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3128757 3131821 - orf19.7229 3128757 3131821 1 3131821 3128757 3131465 3128865 IML2 IPF855.1|Contig4-3043_0019|orf6.8129|CA5353|CaO19.7229 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3132252 3132784 + ntar_280 3132252 3132784 1 3132252 3132784 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 3132811 3134492 - orf19.7231 3132811 3134492 1 3134492 3132811 3134269 3133121 FTR2 orf6.8131|IPF853.1|Contig4-3043_0021|CA5354|CaO19.7231 High-affinity iron permease; not required for mouse systemic virulence; regulated by iron level, ciclopirox olamine, amphotericin B, caspofungin; complements S. cerevisiae ftr1 iron transport defect; probably interacts with ferrous oxidase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3134618 3134771 - ntar_281 3134618 3134771 1 3134771 3134618 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 3135470 3138938 - orf19.7232 3135470 3138938 1 3138938 3135470 3138881 3135612 IRR1 IPF850.1|Contig4-3043_0023|orf6.8132|orf6.8133|CA5355|CA5356|orf19.7233|IRR1.3f Predicted ORF in Assemblies 19, 20 and 21; cell-cycle regulated periodic mRNA expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3139177 3140969 + orf19.7234 3139177 3140969 1 3139177 3140969 3139214 3140899 IPF848.1|Contig4-3014_0004|orf6.8134|CA5357|CaO19.7234|RSC8 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3140971 3143888 - orf19.7235 3140971 3143888 1 3143888 3140971 3143753 3141075 IPF846.1|Contig4-3014_0006|orf6.8135|CA5358|CaO19.7235|IPF846 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to amphotericin B [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3144200 3145181 - orf19.7236 3144200 3145181 1 3145181 3144200 3145130 3144291 TIF35 IPF842.1|Contig4-3014_0009|orf6.8136|CA5359|CaO19.7236 Putative translation initiation factor; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3145289 3146460 + orf19.7237 3145289 3146460 1 3145289 3146460 3145510 3146313 IPF839.1|Contig4-3014_0013|orf6.8137|CA5360|CaO19.7237|IPF839 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3146294 3147677 - orf19.7238 3146294 3147677 1 3147677 3146294 3147648 3146788 NPL3 IPF837.1|Contig4-3014_0016|orf6.8138|CA5361|CaO19.7238 Putative RNA-binding protein, ortholog of S. cerevisiae Npl3p; nuclear export is facilitated by Hmt1p; transcription is upregulated in an RHE model of oral candidiasis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 3148005 3150406 - orf19.7239 3148005 3150406 2 3150406|3150054 3150303|3148005 3150328 3148098 IPF836.1|Contig4-3014_0017|orf6.8139|CA5362|IPF836.3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=F] Ca21chr1 3151059 3154910 - orf19.7242 3151059 3154910 1 3154910 3151059 3154898 3151128 NCR1 IPF829.1|Contig4-3014_0027|orf6.8142|CA5363|CaO19.7242 Transcription is regulated by Nrg1p and Mig1p; increased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3155133 3156307 + orf19.7243 3155133 3156307 1 3155133 3156307 3155237 3156250 IPF825.1|Contig4-3014_0028|orf6.8143|CA5364|CaO19.7243|DCD1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3156186 3157085 - orf19.7244 3156186 3157085 1 3157085 3156186 3156949 3156254 IPF824.1|Contig4-3014_0029|orf6.8144|CA5365|FAH1|CaO19.7244|IPF824 Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide in yhb1 mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3157175 3158582 + orf19.7245 3157175 3158582 1 3157175 3158582 3157230 3158501 IPF823.1|Contig4-3014_0031|orf6.8145|CA5366|CaO19.7245|IPF823 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3158572 3160835 - orf19.7247 3158572 3160835 1 3160835 3158572 3160657 3158672 RIM101 orf6.8147|HRM101|PRR2|IPF822.2|Contig4-3014_0032|CA5367|CaO19.7247 Transcription factor involved in alkaline pH response; required for alkaline-induced hyphal growth; role in virulence in mouse systemic infection; activated by C-terminal proteolytic cleavage; mediates both positive and negative regulation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3161228 3161695 + ntar_282 3161228 3161695 1 3161228 3161695 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 3162261 3162851 + orf19.7250 3162261 3162851 1 3162261 3162851 3162285 3162728 IPF5257.1|Contig4-2986_0001|orf6.8150|CA5368|YPI2|CaO19.7250|IPF5257 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3162739 3164447 - orf19.7251 3162739 3164447 1 3164447 3162739 3164394 3162919 WSC4 IPF5256.1|Contig4-2986_0002|orf6.8151|CA5369|CaO19.7251 Transcription is specific to white cell type [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3164929 3165252 + orf19.7252 3164929 3165252 1 3164929 3165252 3164929 3165252 IPF27358.1|orf6.8152|CaO19.7252 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 3165574 3167505 - orf19.7254 3165574 3167505 1 3167505 3165574 3167470 3165671 IPF5248.1|Contig4-2986_0003|Contig4-2986_0005|orf6.8154|CA5370|CaO19.7254|IPF5248 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3167557 3167950 + orf19.7255 3167557 3167950 1 3167557 3167950 3167578 3167799 RPC10 IPF5246.1|Contig4-2986_0006|orf6.8155|CA5371|CaO19.7255 Predicted ORF in Assemblies 19, 20 and 21; flucytosine induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3167785 3169721 - orf19.7257 3167785 3169721 1 3169721 3167785 3169721 3167811 IPF5245.2|Contig4-2986_0007|orf6.8157|CA5372|CaO19.7257|MLH3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr1 3169692 3171106 + orf19.7258 3169692 3171106 1 3169692 3171106 3170037 3171008 DDI1 IPF5241.2|Contig4-2986_0012|orf6.8158|CA5374|CaO19.7258 Predicted ORF in Assemblies 19, 20 and 21; macrophage/pseudohyphal-repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr1 3170951 3171784 - orf19.7260 3170951 3171784 1 3171784 3170951 3171784 3171005 IPF5239.2|Contig4-2986_0013|orf6.8160|CA5375|CaO19.7260|IPF5239 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 3171793 3173200 - orf19.7261 3171793 3173200 1 3173200 3171793 3173195 3171846 IPF5237.2|Contig4-2986_0014|orf6.8161|CA5376|CaO19.7261|GDI1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 3173216 3174616 - orf19.7263 3173216 3174616 1 3174616 3173216 3174603 3173251 IPF5234.2|Contig4-2986_0015|Contig4-2986_0016|orf6.8163|CA5377|CaO19.7263|IPF5234 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 3174674 3175633 + orf19.7264 3174674 3175633 1 3174674 3175633 3174695 3175633 IPF5231.1|Contig4-2986_0017|orf6.8164|CA5378|CaO19.7264|RPN11|MPR1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 3175688 3176416 + orf19.7265 3175688 3176416 1 3175688 3176416 3175688 3176416 IPF5228.1|Contig4-2986_0018|orf6.8165|CA5379|UBP10|CaO19.7265|IPF5228.5 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 3176504 3176857 + orf19.7266 3176504 3176857 1 3176504 3176857 3176504 3176818 IPF5225.1|Contig4-2986_0021|orf6.8166|CaO19.7266 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 3176747 3177547 - orf19.7267 3176747 3177547 1 3177547 3176747 3177540 3176785 IPF5224.1|Contig4-2986_0022|orf6.8167|CA5380|CaO19.7267|IPF5224 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 3177571 3178435 - orf19.7269 3177571 3178435 1 3178435 3177571 3178260 3177598 IPF5222.1|Contig4-2986_0024|orf6.8169|CA5381|CaO19.7269|PAA11|IPF5222 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 3178674 3178901 - ntar_283 3178674 3178901 1 3178901 3178674 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 3178762 3180945 + orf19.7270 3178762 3180945 1 3178762 3180945 3179728 3180789 IPF5217.1|Contig4-2986_0029|orf6.8170|CA5382|CaO19.7270|IPF5217 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 3180927 3181775 - ntar_284 3180927 3181775 1 3181775 3180927 3181480 3181295 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 3180978 3181907 + orf19.7271 3180978 3181907 1 3180978 3181907 3181309 3181629 IPF5214.1|Contig4-2986_0030|orf6.8171|CaO19.7271 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr1 3182792 3183124 - orf19.7272 3182792 3183124 1 3183124 3182792 3183124 3182792 IPF13996.1|Contig4-2986_0033|orf6.8172|CaO19.7272 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 3183339 3184316 - orf19.7274 3183339 3184316 1 3184316 3183339 3184316 3183339 IPF14001.1|Contig4-2250_0004|Contig4-2250_0005|Contig4-2986_0035|orf6.8173|orf6.8174|CA5383|CA5384|orf19.7273|Zorro1b.5f Predicted ORF in retrotransposon Zorro2 with similarity to retroviral reverse transcriptase proteins [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 3183482 3183769 + ntar_285 3183482 3183769 1 3183482 3183769 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr1 3184588 3185304 - orf19.7275 3184588 3185304 1 3185304 3184588 3185304 3184588 FGR24 IPF14003.1|Contig4-2250_0008|Contig4-2250_0010|orf6.8175|orf6.8177|CA5385|Zorro2b.3f Protein encoded in retrotransposon Zorro2 with similarity to retroviral endonuclease-reverse transcriptase proteins; lacks an ortholog in S. cerevisiae; transposon mutation affects filamentous growth [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 3185382 3185909 - orf19.7277 3185382 3185909 1 3185909 3185382 3185909 3185382 orf6.8177|CA5386|CaO19.7277|Zorro2b.5f|IPF14005.1 Predicted ORF in retrotransposon Zorro2 with similarity to zinc finger-containing retroviral nucleocapsid proteins; un-merged from orf19.7275 in a revision of Assembly 21 based on comparative genome analysis and new sequence data [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr1 3186501 3187101 - orf19.7276.1 3186501 3187101 1 3187101 3186501 3186870 3186670 TLO4 IPF14006.2|CA5387|CTA213.3|CTA24.3 Member of a family of telomere-proximal genes of unknown function; transcription is upregulated in an RHE model of oral candidiasis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr1 3187867 3188547 - orf19.7278 3187867 3188547 1 3188547 3187867 3188133 3187867 [label_first_exon=CGD label_last_exon=CGD orf_changed=true scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 83 854 - ntar_286 83 854 1 854 83 652 530 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 4248 4778 + orf19.1925 4248 4778 1 4248 4778 4248 4778 TLO5 orf19.9481|IPF17379.3|IPF14847.1|orf6.1954|orf6.5530|CA0809|TLO5b|CTA222|CaO19.9481|CTA212|CaO19.1925 Member of a family of telomere-proximal genes of unknown function; may be spliced in vivo [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 5265 5583 - ntar_287 5265 5583 1 5583 5265 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 5655 7363 + orf19.1923 5655 7363 1 5655 7363 5665 7335 RRN3 orf19.9479|IPF19884.2|IPF19708.1|orf6.1957|CA0810|CaO19.1923|CaO19.9479 Predicted ORF in Assemblies 19, 20 and 21; caspofungin induced, flucytosine repressed; downregulated in core stress response; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 7396 7467 - tv(cac)1 7396 7467 1 7467 7396 tV(CAC)1.2 tRNA-Val predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 7510 8043 - orf19.1920 7510 8043 1 8043 7510 8043 7510 orf19.9476|IPF25405.1|IPF17625.2|orf6.1959|CA0811|CIS301|CaO19.1920|CaO19.9476|IPF17625 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 8106 9289 - orf19.1917 8106 9289 1 9289 8106 9289 8144 orf19.9473|IPF25402.1|IPF16243.2|orf6.1962|CA0812|CaO19.1917|AES6|CaO19.9473|IPF3348 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 9319 11063 - orf19.1915 9319 11063 1 11063 9319 11063 9360 MPP10 orf19.9471|IPF19846.2|IPF16234.2|orf6.1964|orf6.803|CA0813|CaO19.1915 Predicted ORF in Assemblies 19, 20 and 21; downregulated in core stress response; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 11100 12537 - orf19.1914 11100 12537 1 12537 11100 12443 11100 FAV3 orf19.9470|IPF15437.1|IPF16233.1|Contig4-2107_0001|orf6.1965|orf6.802|CA0814|AMAN6|CaO19.1914|IPF16233 Induced by mating factor in MTLa/MTLa opaque cells [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 12626 13348 + orf19.1913 12626 13348 1 12626 13348 12627 13253 orf19.9469|IPF15439.1|IPF16231.2|Contig4-2107_0003|orf6.1966|orf6.801|CA0815|CaO19.1913|IPF16231 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 13211 14499 - orf19.1911 13211 14499 1 14499 13211 14415 13261 PGA52 orf19.9467|IPF15442.1|IPF14463.2|Contig4-2107_0004|Contig4-2832_0018|orf6.1967|orf6.799|CA0188|CaO19.1911|IPF15442 GPI-anchored cell surface protein of unknown function; fluconazole-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 14811 15573 + orf19.1910 14811 15573 1 14811 15573 14823 15446 orf19.9466|IPF15444.2|IPF14465.1|Contig4-2832_0017|orf6.1269|orf6.798|CA0389|CaO19.1910|IPF14465 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 15434 17652 - orf19.1907 15434 17652 1 17652 15434 17610 15457 EMC9 orf19.9463|IPF14468|IPF25401.1|IPF14468.2|Contig4-2832_0014|Contig4-2832_0015|orf6.1266|orf6.797|CA0388|CaO19.1907 Protein not essential for viability, induced during the mating process [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 17572 17955 + ntar_288 17572 17955 1 17572 17955 17572 17775 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 18818 19148 + orf19.1906 18818 19148 1 18818 19148 18818 19147 orf19.9462|IPF25415.1|IPF29267.1|orf6.1265|CaO19.1906|CaO19.9462 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 19400 21344 + orf19.2119 19400 21344 1 19400 21344 19427 21205 NDT80 orf19.9667|IPF25251.1|IPF10318.1|Contig4-2832_0009|orf6.4742|CA2727|NDT801|CaO19.2119|CaO19.9667|IPF10318 Activator of CDR1 induction by antifungal drugs; required for wild-type drug resistance; transcriptionally induced upon antifungal drug treatment; similar to S. cerevisiae Ndt80p, which is a meiosis-specific transcriptional regulator [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr2 21516 22809 + orf19.2117 21516 22809 1 21516 22809 21541 22767 LEU5 orf19.9665|IPF10322.1|IPF29217.1|Contig4-2832_0008|orf6.4744|CA2728|CaO19.2117|CaO19.9665|IPF10322 Predicted ORF in Assemblies 19, 20 and 21; transcription is upregulated in both intermediate and mature biofilms [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 22631 23437 - orf19.2116 22631 23437 1 23437 22631 23431 22793 NAT2 orf19.9664|IPF10323.1|IPF19438.2|Contig4-2832_0007|orf6.118|orf6.4745|CA2729|CaO19.2116 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to toxic ergosterol analog [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 23461 24820 - orf19.2115 23461 24820 1 24820 23461 24816 23512 orf19.9663|IPF10325.2|IPF19439.2|Contig4-2832_0006|orf6.117|orf6.4746|CA2730|CaO19.2115|IPF10325 Putative molybdopterin-converting factor; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 24867 25834 - orf19.2114 24867 25834 1 25834 24867 25825 24914 orf19.9662|IPF25286.1|IPF10326.2|Contig4-2832_0004|orf6.4747|CA2731|URO99|CaO19.9662|CaO19.2114|URIC Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 25989 27473 - orf19.2113 25989 27473 1 27473 25989 27426 26038 orf19.9661|IPF25263.1|IPF10327.2|Contig4-2832_0003|orf6.4748|CA2732|CaO19.2113|PEX30|CaO19.9661|IPF10327 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 27544 28398 + orf19.2112 27544 28398 1 27544 28398 27586 28398 orf19.9660|IPF18423.2|IPF10329.2|Contig4-2832_0002|orf6.4749|CA2733|CaO19.9660|PRP18|CaO19.2112 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 28536 28967 + orf19.2111.2 28536 28967 1 28536 28967 28566 28802 RPL38 IPF25223.1|IPF10330.2|CA2734 Predicted ribosomal protein; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 28863 30079 - orf19.2111 28863 30079 1 30079 28863 30051 28906 orf19.9659|IPF25270.1|IPF19765.1|orf6.4750|CA2735|CaO19.9659|TFG2|CaO19.2111 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 30124 32126 + orf19.2110 30124 32126 1 30124 32126 30175 31563 orf19.9658|IPF25264.1|IPF15421.2|Contig4-1579_0002|orf6.4751|CA2736|CaO19.9658|ATE1|CaO19.2110 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 31508 32634 - orf19.2108 31508 32634 1 32634 31508 32587 31637 SOD6 orf19.9656|PGA9|IPF25284.1|IPF15423.2|SOD33|Contig4-1579_0007|Contig4-1856_0002|orf6.4753|CA2737|CaO19.9656|CaO19.2108|IPF15423 Copper- and zinc-containing superoxide dismutase; expression regulated during planktonic growth; member of a gene family that includes SOD1, SOD4, SOD5, and SOD6; gene may contain an intron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 33011 33800 + orf19.2107.1 33011 33800 1 33011 33800 33351 33620 STF2 IPF25220.1|IPF15425.2|Contig4-1856_0004|CA2738 Protein involved in ATP biosynthesis; decreased expression in hyphae compared to yeast-form cells; downregulated by Efg1p; transcription is upregulated in clinical isolates from HIV+ patients with oral candidiasis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 33610 34884 - orf19.2107 33610 34884 2 34884|34727 34784|33610 34856 33682 MUQ1 orf19.9655|IPF25279.1|IPF10634.2|Contig4-1856_0005|orf6.4754|CA2739|CaO19.2107|CaO19.9655 Protein described as choline phosphate cytidylyltransferase/phosphoethanolamine cytidylyltransferase; decreased expression in hyphae compared to yeast-form cells [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 34925 35744 - orf19.2106 34925 35744 1 35744 34925 35686 34979 orf19.9654|IPF25293.1|IPF10633.1|Contig4-2610_0003|orf6.4755|CA2740|CaO19.9654|CaO19.2106|IPF10633 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 35757 36429 - orf19.2105 35757 36429 1 36429 35757 36407 35757 orf19.9653|IPF25303.1|IPF10632.1|Contig4-2610_0004|orf6.4756|CA2741|CaO19.9653|CWC24|CaO19.2105|IPF10632 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 36486 37334 + orf19.2104 36486 37334 1 36486 37334 36551 37180 orf19.9652|IPF18422.2|IPF10631.1|Contig4-2610_0005|orf6.4757|CA2742|JAC1|CaO19.2104|CaO19.9652 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 37152 38400 - orf19.2102 37152 38400 1 38400 37152 38158 37277 CKB1 orf19.9650|CKB21|IPF25288.1|IPF10630.1|Contig4-2610_0007|orf6.4759|CA2743|CaO19.2102|CaO19.9650 Regulatory subunit of protein kinase CK2 (casein kinase II), beta subunit [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 37603 38049 + orf19.2103 37603 38049 1 37603 38049 37603 38049 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 38505 39372 + orf19.2101 38505 39372 1 38505 39372 38528 39127 orf19.9649|IPF25301.1|IPF10626.1|Contig4-2610_0009|orf6.4760|CA2744|CaO19.2101|CaO19.9649|IPF10626 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 38912 41976 - orf19.2099 38912 41976 2 41976|41842 41909|38912 41945 39156 orf19.9647|IPF10625.2|IPF29209.1|Contig4-2610_0010|orf6.4762|CA2745|HIR1|CaO19.2099|CaO19.9647|HIR1.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 42026 43631 - orf19.2098 42026 43631 1 43631 42026 43586 42111 ARO8 orf19.9645|IPF10616.3|IPF1147.2|Contig4-2564_0008|orf6.4764|orf6.7457|CA4804|CaO19.2098 Aromatic transaminase of the Ehrlich fusel oil pathway of aromatic alcohol biosynthesis; Rim101p-independent pH-regulation (alkaline induced); protein abundance is affected by URA3 expression in the CAI-4 strain background; Gcn4p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 44195 47584 + orf19.2097 44195 47584 1 44195 47584 44288 47542 orf19.9644|IPF25340.1|IPF1153.2|Contig4-2564_0004|Contig4-2564_0005|Contig4-2564_0006|orf6.7458|CA4805|RAD5|CaO19.9644|CaO19.2097 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 47572 49832 - orf19.2095 47572 49832 1 49832 47572 49686 47587 orf19.9642|IPF25234.1|IPF1155.2|Contig4-2564_0001|orf6.7460|CA4806|CaO19.9642|CaO19.2095|IPF1155 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 50021 50281 - ntar_289 50021 50281 1 50281 50021 50281 50066 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 50241 53330 + orf19.2094 50241 53330 1 50241 53330 50262 53276 PDR6 orf19.9641|IPF25339.1|IPF1158.2|Contig4-2971_0021|Contig4-2971_0023|Contig4-2971_0025|Contig4-2971_0026|Contig4-2971_0027|orf6.7461|CA4807|KAP122|CaO19.9641|CaO19.2094 Transcription is regulated by Nrg1p; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 53264 55253 - orf19.2093 53264 55253 1 55253 53264 55237 53363 RFA1 orf19.9640|IPF25239.1|IPF1160.1|Contig4-2971_0020|orf6.7462|CA4808|CaO19.9640|CaO19.2093 Protein described as DNA replication factor A; RNA abundance regulated by cell cycle, tyrosol and cell density [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 55355 56780 - orf19.2092 55355 56780 1 56780 55355 56710 55496 orf19.9639|IPF25274.1|IPF1162.1|Contig4-2971_0019|orf6.7463|CA4809|STR3|CaO19.2092|CaO19.9639|IPF1162 Predicted ORF in Assemblies 19, 20 and 21; Gcn4p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 56885 57899 - orf19.2091 56885 57899 1 57899 56885 57810 57079 orf19.9638|IPF25295.1|IPF1164.2|Contig4-2971_0016|orf6.7464|CA4810|CaO19.2091|CaO19.9638|IPF1164 Predicted ORF in Assemblies 19, 20 and 21; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 59037 62998 - orf19.2090 59037 62998 1 62998 59037 62936 59145 orf19.9637|IPF25327.1|IPF1169.2|Contig4-2971_0013|orf6.7465|CA4811|CaO19.9637|ECM16|CaO19.2090 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 63170 64283 + orf19.2089 63170 64283 2 63170|63360 63284|64283 63257 64177 orf19.9636|IPF25290.1|IPF1171.1|Contig4-2971_0010|orf6.7466|CA4812|CaO19.9636|NYV1|CaO19.2089|IPF1171.3f|IPF1171 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 64008 65038 - orf19.2088 64008 65038 1 65038 64008 64994 64209 orf19.9635|IPF25294.1|IPF1174.1|Contig4-2971_0009|orf6.7467|CA4813|CaO19.2088|DPB4|CaO19.9635 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 65148 66314 + orf19.2087 65148 66314 1 65148 66314 65234 66292 SAS2 orf19.9634|IPF25278.1|IPF1176.1|Contig4-2971_0008|orf6.7468|CA4814|CaO19.9634|CaO19.2087 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 66243 68433 - orf19.2084 66243 68433 1 68433 66243 68137 66344 CDH1 orf19.9631|IPF25246.1|IPF20022.1|Contig4-2971_0006|orf6.7471|CA4815|CaO19.2084|CaO19.9631 Predicted ORF in Assemblies 19, 20 and 21; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 69105 70412 + orf19.2082 69105 70412 1 69105 70412 69105 70412 SAP30 orf19.9629|IPF25266.1|IPF1183.2|Contig4-2971_0003|orf6.7473|CA4816|BAR1|CaO19.9629|CaO19.2082|IPF1183 Aspartic-type endopeptidase involved in degradation of alpha pheromone; functional equivalent of S. cerevisiae Bar1p; specific to a-cells; transcription is induced in response to alpha pheromone [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 70624 74591 + orf19.2081 70624 74591 1 70624 74591 70672 74457 orf19.9628|IPF25328.1|IPF1191.2|orf6.7474|CA4817|POM152|CaO19.2081|CaO19.9628 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 74497 75167 - orf19.2079 74497 75167 1 75167 74497 74922 74578 PHHB orf19.9626|IPF25331.1|IPF1193.1|Contig4-3072_0032|orf6.7476|CA4818|CaO19.9626|CaO19.2079|IPF1193 Transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 75534 77752 + orf19.2078 75534 77752 1 75534 77752 75598 77607 orf19.9625|IPF25237.1|IPF1194.2|Contig4-3072_0031|orf6.7477|CA4819|APM2|CaO19.2078|CaO19.9625|IPF1194 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 78045 80744 + orf19.2077 78045 80744 1 78045 80744 78128 80632 ZCF9|orf19.9624|IPF25229.1|IPF1196.2|Contig4-3072_0028|orf6.7478|CA4820|CaO19.9624|CaO19.2077|IPF1196 Putative transcription factor with zinc cluster DNA-binding motif; hypersensitive to toxic ergosterol analog ECC69 and/or ECC1384 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 80810 82010 + orf19.2076 80810 82010 1 80810 82010 80950 81954 orf19.9623|IPF25282.1|IPF1197.1|Contig4-3072_0026|orf6.7479|CA4821|CaO19.9623|CaO19.2076|IPF1197 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 82648 84294 + orf19.2075 82648 84294 1 82648 84294 82837 84192 DFG5 orf19.9622|IPF25260.1|IPF1199.1|Contig4-3072_0022|orf6.7480|CA4822|CaO19.2075|CaO19.9622 N-linked mannoprotein of cell wall and membrane; possible signal transducer; role in hyphal growth and HWP1 induction in alkaline pH; GPI modification predicted; dfg5 dcw1 double mutant is inviable; caspofungin-induced, fungal-specific [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 84527 84835 + orf19.2074 84527 84835 1 84527 84835 84527 84835 orf19.9621|IPF25336.1|IPF29235.1|orf6.7481|CaO19.2074|CaO19.9621 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 84814 86806 + orf19.2073 84814 86806 1 84814 86806 84814 86646 orf19.9620|IPF25244.1|IPF1203.2|Contig4-3072_0021|orf6.7482|CA4823|CaO19.2073|MTE2|CaO19.9620|ERC3 Predicted ORF in Assemblies 19, 20 and 21; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 87382 87528 - ntar_290 87382 87528 1 87528 87382 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 87820 89457 - ntar_291 87820 89457 1 89457 87820 88514 88335 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 87933 89642 + orf19.2072 87933 89642 1 87933 89642 87933 89642 orf19.9619|IPF25249.1|IPF1204.2|Contig4-3072_0019|orf6.7483|CA4824|HNM2|CaO19.2072|HNM1|CaO19.9619 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 89866 90342 + orf19.2071 89866 90342 1 89866 90342 89866 90342 orf19.9618|IPF25310.1|IPF1205.2|Contig4-3072_0017|orf6.7484|CA4825|CaO19.9618|CaO19.2071|IPF1205 Predicted ORF in Assemblies 19, 20 and 21; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 90606 92568 + orf19.2070 90606 92568 2 90606|90759 90685|92568 90652 92431 orf19.9617|IPF25250.1|IPF1206.2|Contig4-3072_0015|orf6.7485|CA4826|CaO19.2070|CaO19.9617|IPF1206 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 92489 94278 - orf19.2069 92489 94278 1 94278 92489 94103 92559 SMF3 orf19.9616|IPF25259.1|IPF1207.1|SMF2|Contig4-3072_0013|Contig4-3072_0014|orf6.7486|CA4827|CaO19.9616|CaO19.2069 Protein described as vacuolar iron transporter; alkaline upregulated; caspofungin repressed; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 95078 96770 + orf19.2068 95078 96770 1 95078 96770 95127 96707 orf19.9615|IPF25256.1|IPF1209.2|Contig4-3072_0010|orf6.7487|CA4828|CaO19.9615|CaO19.2068|IPF1209 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 96451 97580 - orf19.2067 96451 97580 1 97580 96451 97528 96815 orf19.9614|IPF25292.1|IPF1210.1|Contig4-3072_0008|orf6.7488|CA4829|CaO19.2067|NFU1|CaO19.9614|IPF1210 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 97671 98414 - orf19.2066.1 97671 98414 2 98414|98093 98351|97671 98414 97963 CA4830|ATP8|ATP8.exon2|IPF1211.1 Predicted ORF in Assembly 20 and 21; gene has intron [label_first_exon=CGD label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 98524 99589 - orf19.2066 98524 99589 1 99589 98524 99589 98618 orf19.9613|IPF25283.1|IPF1212.1|Contig4-3072_0006|orf6.7489|CA4831|CaO19.9613|CaO19.2066|IPF1212 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 99694 100768 - orf19.2065 99694 100768 1 100768 99694 100722 99694 orf19.9612|IPF25281.1|IPF1213.1|Contig4-3072_0005|orf6.7490|CA4832|CaO19.2065|DAL2|CaO19.9612 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 101403 104787 + orf19.2064 101403 104787 1 101403 104787 101403 104726 orf19.9611|IPF25337.1|IPF1216.2|Contig4-3072_0003|Contig4-3072_0004|CA4833|CaO19.9611|CaO19.2064|IPF1216|orf6.7491 Putative transcription factor with zinc finger DNA-binding motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr2 104710 104929 - ntar_292 104710 104929 1 104929 104710 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 105012 108607 + orf19.2063 105012 108607 1 105012 108607 105012 108482 orf19.9610|IPF25329.1|IPF1217.2|Contig4-3065_0035|orf6.7492|CA4834|CaO19.9610|CaO19.2063|IPF1217 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr2 108613 109734 - orf19.2062 108613 109734 1 109734 108613 109376 108678 SOD4 orf19.9609|PGA2|IPF25297.1|IPF1218.1|Contig4-3065_0001|orf6.7493|CA4835|SOD32|CaO19.9609|CaO19.2062|IPF1218 Copper- and zinc-containing superoxide dismutase; role in response to host innate immune ROS; regulated on white-opaque switching; ciclopirox olamine induced; caspofungin repressed; member of family that includes SOD1, SOD4, SOD5, and SOD6 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 109843 110009 - ntar_293 109843 110009 1 110009 109843 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 110767 111087 - orf19.2061 110767 111087 1 111087 110767 111087 110767 orf19.9608|IPF25332.1|IPF29231.1|orf6.7494|CaO19.9608|CaO19.2061 Protein not essential for viability [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 111141 112295 - orf19.2060 111141 112295 1 112295 111141 112012 111326 SOD5 orf19.9607|PGA3|orf6.7495|IPF1222|IPF25296.1|IPF1222.2|Contig4-3065_0005|CA4836|CaO19.2060|SOD31|CaO19.9607 Copper- and zinc-containing superoxide dismutase; protective role against oxidative stress; induced by neutrophil contact, hyphal growth, caspofungin, osmotic or oxidative stress; member of a gene family including SOD1, SOD4, SOD5, and SOD6 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 114738 116177 + orf19.2059 114738 116177 1 114738 116177 115265 116176 orf19.9606|IPF25287.1|IPF1228.2|Contig4-3065_0008|orf6.7496|CA4837|CaO19.2059|EEP2|CaO19.9606|IPF1228 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 116667 119759 + orf19.2057 116667 119759 1 116667 119759 117048 119588 orf19.9604|IPF25224.1|IPF1231.2|Contig4-3065_0009|orf6.7498|CA4838|CaO19.9604|YTA12|CaO19.2057 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 119781 121280 + orf19.2055 119781 121280 1 119781 121280 119825 121174 NPL6 orf19.9602|IPF25269.1|IPF1234.2|Contig4-3065_0011|orf6.7500|CA4839|CaO19.9602|CaO19.2055 Putative nuclear protein localization factor; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 121116 122933 - orf19.2054 121116 122933 1 122933 121116 122850 121294 FGR15 orf19.9601|IPF25258.1|IPF1235.1|Contig4-3065_0012|orf6.7501|CAS2|CA4840|CaO19.2054|CaO19.9601|IPF1235 Putative transcription factor with zinc finger DNA-binding motif; lacks an ortholog in S. cerevisiae; transposon mutation affects filamentous growth; caspofungin induced; mutation causes marginal increase in caspofungin sensitivity [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 123612 126920 - orf19.2051 123612 126920 2 126920|126569 126783|123612 126818 123717 orf19.9599|IPF25219.1|IPF29223.1|IPF7466.3|Contig4-3065_0015|orf6.431|orf6.5990|CA3659|orf19.2053|IPF7466|CA0077|IPF1239|IPF1239.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=D] Ca21chr2 127053 128867 - orf19.2050 127053 128867 1 128867 127053 128755 127133 orf19.9598|IPF25254.1|IPF7463.2|Contig4-3065_0016|Contig4-3065_0018|orf6.5989|CA3658|TGL1|CaO19.2050|CaO19.9598 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 129828 131079 + orf19.2049 129828 131079 1 129828 131079 130098 130952 orf19.9597|IPF25289.1|IPF7459.1|Contig4-3065_0021|orf6.5988|CA3657|CaO19.2049|CaO19.9597|IPF7459 Predicted ORF in Assemblies 19, 20 and 21; heterozygous null mutant displays sensitivity to virgineone [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 130886 131602 - orf19.2048 130886 131602 1 131602 130886 131488 131123 orf19.9596|orf6.5987|IPF25325.1|IPF7458.1|Contig4-3065_0023|CaO19.2048|CaO19.9596 Transcription is positively regulated by Sfu1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 132108 132996 + orf19.2047 132108 132996 1 132108 132996 132181 132807 orf19.9595|IPF25302.1|IPF7456.1|Contig4-3065_0024|orf6.5986|CA3656|CaO19.9595|CaO19.2047|IPF7456 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to toxic ergosterol analog, and to amphotericin B [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 133145 134542 + orf19.2046 133145 134542 1 133145 134542 133198 134379 POT1-2 orf19.9594|IPF25275.1|IPF7453.1|Contig4-3065_0025|orf6.5985|CA3655|CaO19.9594|POT98|CaO19.2046|POT13 Putative peroxisomal 3-ketoacyl CoA thiolase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 134429 135817 - orf19.2045 134429 135817 1 135817 134429 135647 134610 orf19.9593|IPF25276.1|IPF7452.1|Contig4-3065_0027|orf6.5984|CA3654|CaO19.9593|CaO19.2045|IPF7452 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 136057 137714 - orf19.2044 136057 137714 1 137714 136057 137649 136192 PGA27 orf19.9592|IPF25252.1|IPF7451.2|Contig4-3065_0030|orf6.5983|CA3653|CaO19.9592|CaO19.2044|IPF7451 Putative GPI-anchored protein of unknown function [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 137787 138841 - orf19.2043 137787 138841 1 138841 137787 138754 137852 orf19.9591|IPF25285.1|IPF7450.2|Contig4-3065_0032|orf6.5982|CA3652|CaO19.9591|CaO19.2043|NBP35 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 138800 140513 + orf19.2042 138800 140513 1 138800 140513 138814 140403 orf19.9590|IPF25257.1|IPF7447.2|Contig4-3065_0033|orf6.5981|CA3651|CaO19.9590|MSS1|CaO19.2042 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr2 140374 142541 - orf19.2041 140374 142541 1 142541 140374 142396 140486 orf19.9589|IPF25241.1|IPF4134.2|Contig4-2863_0027|orf6.5980|CA3650|RSC4|CaO19.2041|CaO19.9589|IPF4134 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 142571 144665 + orf19.2040 142571 144665 1 142571 144665 142787 144562 orf19.9588|IPF25245.1|IPF4132.2|Contig4-2863_0024|orf6.5979|CA3649|TAH18|CaO19.9588|CaO19.2040|IPF4132 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr2 144759 146262 + orf19.2039 144759 146262 1 144759 146262 144775 146115 MSF1 orf19.9587|IPF25267.1|IPF4131.2|Contig4-2863_0020|Contig4-2863_0021|orf6.5978|CA3648|CaO19.2039|CaO19.9587 Predicted ORF in Assemblies 19, 20 and 21; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 146097 147513 - orf19.2038 146097 147513 1 147513 146097 147409 146153 orf19.9586|IPF25271.1|IPF4129.1|Contig4-2863_0018|Contig4-2863_0019|orf6.5977|CA3647|CaO19.9586|CaO19.2038|IPF4129 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 148469 149248 + orf19.2037 148469 149248 1 148469 149248 148538 148996 orf19.9585|IPF25312.1|IPF4128.1|orf6.5976|CA3646|CaO19.2037|CaO19.9585|IPF4128 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 148490 149220 - ntar_294 148490 149220 1 149220 148490 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 149554 150713 + orf19.2036 149554 150713 1 149554 150713 149634 150713 orf19.9584|IPF25277.1|IPF4127.2|Contig4-2863_0014|orf6.5975|CA3645|CaO19.9584|DDD1|CaO19.2036|IPF4127 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 150855 151811 + orf19.2035 150855 151811 1 150855 151811 150855 151811 orf19.9583|IPF25280.1|IPF4126.2|Contig4-2863_0013|orf6.5974|CA3644|CaO19.2035|CaO19.9583|IPF4126 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 152021 152710 + orf19.2034 152021 152710 1 152021 152710 152021 152710 orf19.9582|IPF25300.1|IPF4124.2|Contig4-2863_0011|orf6.5973|CA3643|CaO19.2034|CaO19.9582|IPF4124 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 152920 153609 + orf19.2033 152920 153609 1 152920 153609 152920 153609 PGA19 orf19.9581|IPF4123|IPF25299.1|IPF4123.2|Contig4-2863_0009|orf6.5972|CA3642|CaO19.9581|CaO19.2033 [NOT TRANSCRIBED?] Putative GPI-anchored protein; not essential for viability; macrophage-induced gene [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 153706 155386 - orf19.2031 153706 155386 2 155386|155150 155222|153706 155269 154527 VPS24 orf19.9579|IPF19223.2|IPF4120.2|Contig4-2863_0003|orf6.595|orf6.5970|CA3640|CaO19.2031 Protein similar to S. cerevisiae Vps24p, which is a member of the ESCRT III protein sorting complex; downregulated upon adherence to polystyrene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 153805 154473 + orf19.2032 153805 154473 1 153805 154473 153805 154473 orf19.9580|IPF25298.1|IPF4122.2|Contig4-2863_0008|orf6.5971|CA3641|CaO19.2032|CaO19.9580|IPF4122 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 155665 156671 + orf19.2030 155665 156671 1 155665 156671 155824 156297 orf19.9578|IPF4119.2|IPF29221.1|Contig4-2863_0002|orf6.594|orf6.5969|CA0125|CaO19.2030|IPF4119 Predicted ORF in Assemblies 19, 20 and 21; greater mRNA abundance observed in a cyr1 or ras1 homozygous null mutant than in wild type [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 156208 157488 - orf19.2029 156208 157488 1 157488 156208 157441 156353 RFC5 orf19.9577|IPF4118.2|IPF29218.1|Contig4-2863_0001|orf6.593|orf6.5968|CA0124|CaO19.2029 Predicted ORF in Assemblies 19, 20 and 21; periodic mRNA expression, peak at cell-cycle G1/S phase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 157550 157811 + ntar_295 157550 157811 1 157550 157811 157655 157795 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 157654 158482 - orf19.2028 157654 158482 1 158482 157654 158430 157873 MXR1 orf19.9576|IPF4117.2|IPF19262.2|Contig4-2097_0002|orf6.473|orf6.592|CA0123|CaO19.2028 Protein described as a methionine sulfoxide reductase; flucytosine induced; Plc1p-regulated; upregulated in the presence of human neutrophils; macrophage regulated (gene induced, protein decreased); possibly adherence-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 158583 161074 - orf19.2026 158583 161074 1 161074 158583 160795 158693 orf19.9575|IPF19018.2|IPF4114.2|Contig4-2097_0005|orf6.1213|orf6.471|orf6.591|CA0090|CaO19.2026|UBP9|UBP13 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 161361 161705 + orf19.2025 161361 161705 1 161361 161705 161361 161705 IPF29232.1|orf6.470|CaO19.2025 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 161906 162762 - ntar_296 161906 162762 1 162762 161906 162735 162592 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 163117 163552 + orf19.2024 163117 163552 1 163117 163552 163117 163476 IPF25333.1|IPF29228.1|orf6.2375|orf6.1212 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr2 164442 166287 + orf19.2023 164442 166287 1 164442 166287 164467 166107 HGT7 orf19.9572|HXT3|HXT62|IPF3282|HXT61|IPF17561.3|IPF4109.2|Contig4-2603_0002|orf6.1210|orf6.2376|orf6.2378|CA1067|CaO19.2023 Putative glucose transporter, major facilitator superfamily; glucose-, fluconazole-, Snf3p-induced, expressed at high glucose; upregulated in biofilm; C. albicans glucose transporter family comprises 20 members; 12 TM regions predicted [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 167154 169147 + orf19.2021 167154 169147 1 167154 169147 167291 168943 HGT8 orf19.9571|HGT11|HXT3|HXT7|HXT4|IPF18773.1|IPF18774.1|orf6.187|orf6.2377|orf6.2378|HXT5|CA1069|CA1068|orf19.2022|HXT5.3f Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; gene has intron; expressed in rich medium with 2% glucose [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 170134 171951 + orf19.2020 170134 171951 1 170134 171951 170217 171869 HGT6 orf19.9570|HXT4|HXT61|IPF25253.1|IPF4104.2|Contig4-2305_0001|orf6.2379|CA1070|CaO19.2020|HXT63|CaO19.9570 Putative glucose transporter of major facilitator superfamily; 20 members of C. albicans glucose transporter family; 12 probable membrane-spanning segments; core stress response, fluconazole-induced; expressed in rich medium with 2% glucose [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 172312 173077 + orf19.2019 172312 173077 1 172312 173077 172345 172986 orf19.9569|IPF4102.2|IPF19890.2|Contig4-2305_0004|orf6.2113|orf6.2380|CA0910|MRPL16|CaO19.2019 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 173109 173561 + orf19.2018.1 173109 173561 2 173109|173409 173350|173561 173155 173527 Predicted ORF in Assembly 20 and 21; gene has intron; similar to human BLOC1S2 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 173355 174486 - orf19.2018 173355 174486 1 174486 173355 174401 173952 orf19.9568|IPF14814.2|IPF18772.2|Contig4-1775_0003|orf6.2114|orf6.2381|CA0911|CaO19.2018|JJJ3|IPF14814 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 173688 173945 + orf19.2018.2 173688 173945 1 173688 173945 173688 173945 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 174461 175850 + orf19.2017 174461 175850 1 174461 175850 174599 175780 orf19.9567|IPF14813.2|IPF14812.3|Contig4-1775_0004|Contig4-1775_0006|orf6.2115|CA0912|CaO19.9567|RPA49|CaO19.2017 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 175924 176042 - tl(caa)2 175924 176042 2 176042|175967 176004|175924 tL(CAA)2.2 tRNA-Leu predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 176331 176990 - orf19.2016 176331 176990 1 176990 176331 176936 176520 orf19.9566|IPF14810.2|IPF29222.1|orf6.2116|CA0913|CaO19.9566|CaO19.2016|IPF14810 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 177194 177851 - ntar_297 177194 177851 1 177851 177194 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 178024 178323 + ntar_298 178024 178323 1 178024 178323 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 178038 179719 - orf19.2014 178038 179719 1 179719 178038 179692 178316 BCY1 orf19.9565|SRA1|orf6.573|orf6.2117|IPF19590.1|IPF19228.1|IPF19591.1|Contig4-2036_0005|Contig4-2036_0006|orf6.574|CA0914|orf19.2015 Regulatory subunit of protein kinase A; required for nuclear localization of Tpk1p; physically interacts with Tpk1p; essential for viability; apoptosis-regulated; bcy1 heterozygous or bcy1 tpk2 mutant has filamentous growth defect [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 180115 180254 - ntar_299 180115 180254 1 180254 180115 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 180729 182965 + orf19.2013 180729 182965 1 180729 182965 180800 182863 KAR2 orf19.9564|orf6.572|IPF15827.2|IPF19229.2|Contig4-1979_0005|orf6.2118|orf6.779|CA0915|CaO19.2013 Similar to chaperones of Hsp70p family; transcriptionally regulated by iron; expression greater in high iron; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 183402 185926 + orf19.2012 183402 185926 2 183402|183563 183424|185926 183402 185876 NOT3 orf19.9563|IPF18023.2|IPF15994.2|Contig4-1979_0003|Contig4-1979_0004|orf6.6349|orf6.778|CA0181|NOT31|CaO19.2012 Protein with similarity to Not5p, putative transcriptional regulator; not required for adherence to buccal epithelial cells or for virulence in mouse systemic infection; null mutant colonies exhibit slightly decreased filamentation ratio [label_first_exon=CGD label_last_exon=CGDmod orf_changed=true scenario_first_exon=Z scenario_last_exon=A] Ca21chr2 185888 186283 - orf19.2010 185888 186283 1 186283 185888 186283 185888 orf19.9561|IPF20150.1|IPF20049.1|Contig4-1979_0001|orf6.6350|orf6.776|CA3932|CaO19.2010|IPF20150 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 186639 188159 + orf19.2009 186639 188159 1 186639 188159 186664 188064 orf19.9560|IPF18281.1|IPF15997.3|Contig4-1590_0004|orf6.6351|orf6.775|CA3933|PEX12|CaO19.2009|IPF18281 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 188291 189621 + orf19.2008 188291 189621 1 188291 189621 188354 189604 orf19.9559|IPF25272.1|IPF17119.2|Contig4-1590_0001|Contig4-1590_0002|orf6.6352|CA3934|CaO19.9559|CaO19.2008|IPF17119 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 189570 192698 - orf19.2007 189570 192698 1 192698 189570 192622 189686 orf19.9558|IPF25347.1|IPF14688.2|Contig4-2862_0002|orf6.6353|CA3935|CaO19.2007|LUV1|CaO19.9558|IPF14688 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 192779 193693 + orf19.2006.1 192779 193693 1 192779 193693 193378 193563 COX17 IPF25343.1|IPF14687.1|Contig4-2862_0004|CA3936 ORF predicted by Annotation Working Group; transcription is upregulated in both intermediate and mature biofilms [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 193688 194888 - orf19.2006 193688 194888 1 194888 193688 194750 193728 orf19.9557|IPF14686.2|IPF29219.1|Contig4-2862_0005|orf6.6354|CA3937|CaO19.2006|IPF14686 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr2 195233 198938 - orf19.2005 195233 198938 1 198938 195233 198415 195380 REG1 orf19.9556|IPF4764.2|IPF29238.1|Contig4-2862_0007|orf6.6355|CA3938|CaO19.2005|IPF4764 Predicted ORF in Assemblies 19, 20 and 21; macrophage/pseudohyphal-induced; possibly transcriptionally regulated upon hyphal formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 199107 199588 - ntar_300 199107 199588 1 199588 199107 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 199625 199984 + ntar_301 199625 199984 1 199625 199984 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 200554 201372 + ntar_302 200554 201372 1 200554 201372 200873 201013 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 201247 203176 - orf19.2003 201247 203176 1 203176 201247 203088 201472 HNM1 orf19.9554|IPF4757.1|IPF19469.2|Contig4-2862_0011|orf6.42|orf6.6357|CA3939|HNM2|CaO19.2003 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to toxic ergosterol analog; shows colony morphology-related gene regulation by Ssn6p; clade-associated gene expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 204059 204638 - ntar_303 204059 204638 1 204638 204059 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 204783 207947 + orf19.2002 204783 207947 1 204783 207947 204929 207811 orf19.9553|IPF4755.2|IPF29205.1|Contig4-1886_0001|orf6.6358|CA3940|NIC96|CaO19.2002 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 207964 208946 + orf19.2001 207964 208946 1 207964 208946 208043 208798 orf19.9552|IPF25291.1|IPF4754.2|orf6.6359|CA3941|CaO19.9552|CaO19.2001|IPF4754 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 208761 211371 - orf19.2000 208761 211371 1 211371 208761 211319 208791 orf19.9551|IPF25226.1|IPF4753.2|Contig4-2876_0001|orf6.6360|CA3942|CHL1|CaO19.2000|CaO19.9551 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 211479 212185 + orf19.1999 211479 212185 1 211479 212185 211535 212116 orf19.9550|IPF18279.2|IPF4751.2|Contig4-2876_0002|orf6.6361|CA3943|CaO19.9550|CaO19.1999|IPF4751 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 212169 214784 - ntar_1416 212169 214784 2 214784|214517 214632|212169 212479 212273 [label_first_exon=CGD label_last_exon=CGD orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr2 212374 214693 + orf19.1998 212374 214693 1 212374 214693 212498 214615 orf19.9549|IPF25233.1|IPF4750.1|Contig4-2876_0006|orf6.6362|CA3944|CaO19.1998|CaO19.9549|IPF4750 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 215370 216684 + orf19.1996 215370 216684 1 215370 216684 215567 216628 CHA1 orf19.9548|orf6.6363|19.9548|CHA2|IPF4749.2|IPF8165.3|IPF29220.1|Contig4-2876_0008|orf6.766|CA3945|CA6267|orf19.1997|CHA12.3f|CHA12 Protein similar to serine/threonine dehydratases, catabolic; negatively regulated by Rim101p; expression greater in low iron; regulated on white-opaque switching; filament induced; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 216930 217045 - tl(uaa)1 216930 217045 2 217045|216975 217007|216930 tL(UAA)1.2 tRNA-Leu predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 217357 218462 - ntar_304 217357 218462 1 218462 217357 217909 217745 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 217654 218064 + ntar_305 217654 218064 1 217654 218064 217748 217873 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 218454 218785 + ntar_306 218454 218785 1 218454 218785 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 218802 218978 - ntar_307 218802 218978 1 218978 218802 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 219235 221605 - orf19.1995 219235 221605 1 221605 219235 221449 219320 orf19.9547|IPF4742.2|IPF17173.3|Contig4-2500_0005|Contig4-2500_0006|orf6.6364|orf6.767|CA3946|MNN22|CaO19.1995|MNN2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 222154 222616 + ntar_308 222154 222616 1 222154 222616 222154 222288 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 222621 223247 - ntar_309 222621 223247 1 223247 222621 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 223477 225692 + orf19.1994 223477 225692 1 223477 225692 223605 225650 orf19.9546|IPF25236.1|IPF14768.2|Contig4-2198_0005|orf6.6365|CA3947|CaO19.9546|SNX41|CaO19.1994|IPF14768 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 225952 227504 + orf19.1993 225952 227504 1 225952 227504 226005 227255 orf19.9545|IPF25273.1|IPF14766.2|Contig4-2198_0009|orf6.6366|CA3948|RPN9|CaO19.1993|CaO19.9545 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr2 227543 229233 - orf19.1992 227543 229233 1 229233 227543 229131 227572 SIR2 orf19.9544|IPF17303.2|IPF18997.2|orf6.6367|CA3949|SIR21|CaO19.1992 Required for wild-type lifespan, asymmetric inheritance of oxidatively damaged proteins, rDNA silencing; regulates phenotypic switching in strain 3153A, not WO-1; partially functionally complements S. cerevisiae sir2 mutant mating defect [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 230312 232374 + orf19.1991 230312 232374 1 230312 232374 230378 232237 orf19.9542|IPF19793.1|IPF16743.2|Contig4-1687_0002|orf6.1291|orf6.6369|CA3950|CaO19.1991|PTM1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr2 232328 234628 - orf19.1990 232328 234628 1 234628 232328 234442 232550 SNX4 orf19.9541|IPF25265.1|IPF15225.2|Contig4-2093_0003|Contig4-2093_0004|orf6.1292|orf6.6370|CA0402|CaO19.1990|IPF15225 Protein induced during the mating process [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 234866 236465 - orf19.1989 234866 236465 1 236465 234866 236395 235037 DCW1 orf19.9540|PGA51|IPF25268.1|IPF15224.2|Contig4-2093_0006|orf6.1293|CA0403|CaO19.1989|CaO19.9540|IPF15224 Protein with predicted GPI modification; dfg5 dcw1 double mutant is inviable; not required for wild-type hyphal growth; increased mRNA abundance observed in cyr1 homozygous null mutant (yeast-form or hyphal); fungal-specific [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 237124 239457 - orf19.1441 237124 239457 1 239457 237124 239103 237247 orf19.9016|IPF25761.1|IPF14657.2|Contig4-2134_0003|orf6.1060|CA0284|CaO19.9016|CaO19.1441|IPF14657 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 241096 243457 + orf19.1442 241096 243457 1 241096 243457 241143 243251 PLB4.5 orf19.9017|orf19.9018|IPF15731.2|IPF15733.2|IPF14660.3|IPF29416.1|PLB4.3|Contig4-2174_0003|Contig4-2174_0004|orf6.1059|orf6.795|orf6.796|PLB4|PLB4.5f|PLB4.3f|CA0185|CA0186|orf19.1443 Putative phospholipase B; Hog1p-induced; regulated by Ssn6p; putative GPI-anchor; repressed during cell wall regeneration; clade-associated gene expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 243876 245733 + orf19.1444 243876 245733 1 243876 245733 244023 245591 orf19.9019|IPF17555.3|IPF29409.1|Contig4-2174_0001|orf6.7129|CA4555|ENT2|CaO19.1444|CA0187|IPF15734|IPF15734.1|IPF17555.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 245742 248619 - orf19.1445 245742 248619 1 248619 245742 248531 245820 ESC4 orf19.9020|IPF25740.1|IPF7874.2|Contig4-3018_0027|Contig4-3018_0028|orf6.7128|CA4554|CaO19.9020|CaO19.1445|IPF7874 Protein similar to S. cerevisiae Esc4p, which represses transposition; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 248807 251617 - orf19.1446 248807 251617 1 251617 248807 250508 249030 CLB2 orf19.9021|IPF25776.1|IPF7873.2|CYB1|Contig4-3018_0026|orf6.7127|CA4553|CaO19.9021|CaO19.1446 B-type mitotic cyclin (cyclin-dependent protein kinase regulatory subunit); essential; required for wild-type mitotic exit; role in cell polarization; interacts with catalytic subunit Cdk1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 252317 252519 - ntar_310 252317 252519 1 252519 252317 252484 252341 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 253735 253869 + ntar_311 253735 253869 1 253735 253869 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 254298 256293 - orf19.1447 254298 256293 1 256293 254298 256196 254580 orf19.9022|IPF25767.1|IPF7869.1|Contig4-3018_0021|orf6.7126|CA4552|CaO19.1447|CaO19.9022|IPF7869 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 256675 257518 + orf19.1448 256675 257518 1 256675 257518 256733 257299 APT1 orf19.9023|IPF25817.1|IPF7867.1|Contig4-3018_0020|orf6.7125|CA4551|CaO19.9023|CaO19.1448 Predicted ORF in Assemblies 19, 20 and 21; flucytosine induced; repressed by nitric oxide; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 257328 257905 - orf19.1448.1 257328 257905 2 257905|257694 257824|257328 257845 257441 Predicted ORF in Assembly 20 and 21; gene has intron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 258078 258780 - orf19.1449 258078 258780 1 258780 258078 258767 258078 orf19.9024|IPF25807.1|IPF7863.1|IPF7863|Contig4-3018_0017|orf6.7124|CA4549|CaO19.1449|CaO19.9024 Increased transcription is observed in an azole-resistant strain that overexpresses MDR1; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr2 259049 260155 - orf19.1450 259049 260155 1 260155 259049 260155 259049 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 260740 265822 + orf19.1451 260740 265822 1 260740 265822 260784 265781 SRB9 orf19.9026|IPF25829.1|IPF6242.2|Contig4-3018_0009|Contig4-3018_0011|Contig4-3018_0012|Contig4-3018_0014|orf6.7122|CA4547|orf6.514|CaO19.9026|SSN2|CaO19.1451 Protein with similarity to S. cerevisiae Srb9p transcription mediator; transposon mutation affects filamentous growth; suppresses S. cerevisiae diploid filamentous (flo8, ste7, ste12, tec1) or haploid invasive (flo8) mutant growth defects [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 265918 268971 + orf19.1453 265918 268971 1 265918 268971 265953 268823 SPT5 orf19.9028|IPF25736.1|IPF6247.1|Contig4-3018_0007|orf6.7120|CA4546|CaO19.9028|CaO19.1453 Protein similar to S. cerevisiae Spt5p transcription elongation factor; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 268825 270558 - orf19.1457 268825 270558 1 270558 268825 270508 268985 orf19.9032|IPF25773.1|IPF6250.1|Contig4-3018_0004|orf6.7116|CA4545|CaO19.9032|SSL1|CaO19.1457 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr2 270261 270695 + orf19.1456 270261 270695 1 270261 270695 270261 270695 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 270671 271572 - orf19.1458 270671 271572 1 271572 270671 271542 270697 orf19.9033|IPF25800.1|IPF6252.1|Contig4-3018_0001|orf6.7115|CA4544|CaO19.1458|TAD2|CaO19.9033|IPF6252 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr2 271655 272881 + orf19.1459 271655 272881 1 271655 272881 271750 272832 PPE1 orf19.9034|IPF25793.1|IPF6254.1|orf6.7114|CA4543|CaO19.9034|CaO19.1459 Protein similar to S. cerevisiae Ppe1p; shows genetic interaction with some genes involved in diploid filamentous growth and haploid invasive growth in S. cerevisiae [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 272822 275138 - orf19.1460 272822 275138 1 275138 272822 275001 272857 orf19.9035|IPF25753.1|IPF6255.1|Contig4-2555_0007|orf6.7113|CA4542|CaO19.9035|CaO19.1460|IPF6255 Putative glutamine-dependent NAD synthetase, involved in NAD salvage pathway [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 275432 276770 + orf19.1461 275432 276770 1 275432 276770 275494 276735 orf19.9036|IPF25785.1|IPF6257.1|Contig4-2555_0005|orf6.7112|CA4541|CaO19.9036|CaO19.1461|IPF6257 Predicted ORF in Assemblies 19, 20 and 21; possibly transcriptionally regulated upon hyphal formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr2 277000 279604 + orf19.1462 277000 279604 1 277000 279604 277127 279472 SMP2 orf19.9037|IPF25747.1|IPF6259.2|Contig4-2555_0003|orf6.7111|CA4540|CaO19.1462|CaO19.9037 Transcription is regulated by Nrg1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 279905 282156 + orf19.1464 279905 282156 1 279905 282156 280251 282089 BMT5 orf19.9039|IPF18203.2|IPF6260.2|orf6.7109|CA4539|CaO19.1464|WRY6|CaO19.9039|IFQ4 Putative beta-mannosyltransferase, member of a 9-gene family that includes characterized genes BMT1, BMT2, BMT3, and BMT4 with roles in beta-1,2-mannosylation of cell wall phosphopeptidomannan; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 282310 283037 + orf19.1465 282310 283037 1 282310 283037 282314 282859 orf19.9040|IPF25815.1|IPF20018.1|Contig4-3015_0023|Contig4-3015_0024|orf6.7108|CA4538|CaO19.9040|PAA12|CaO19.1465|IPF20018 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 283089 283942 + orf19.1466 283089 283942 1 283089 283942 283107 283874 REX2 orf19.9041|IPF25805.1|IPF4375.1|Contig4-3015_0021|orf6.7107|CA4537|REX20|CaO19.9041|CaO19.1466|YNT2 Predicted ORF in Assemblies 19, 20 and 21; transcription is upregulated in both intermediate and mature biofilms [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr2 284175 284945 + orf19.1467 284175 284945 1 284175 284945 284229 284633 COX13 orf19.9042|IPF25830.1|IPF4376.1|Contig4-3015_0020|orf6.7106|CA4536|CaO19.9042|CaO19.1467 Predicted ORF in Assemblies 19, 20 and 21; flucytosine induced; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 284750 287106 - orf19.1468 284750 287106 1 287106 284750 286599 285040 orf19.9043|IPF25772.1|IPF4377.1|Contig4-3015_0018|orf6.7105|CA4535|CDC55|CaO19.1468|CaO19.9043 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 287700 288745 - orf19.1470 287700 288745 2 288745|288234 288639|287700 288228 287869 RPS26A orf19.9045|IPF25866.1|IPF4380.2|Contig4-3015_0015|orf6.7103|CA4534|CaO19.1470|RPS26|CaO19.9045 Predicted ribosomal protein; regulated by Nrg1p, Tup1p; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage; intron in 5'-UTR [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr2 289048 289246 - ntar_312 289048 289246 1 289246 289048 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 289361 290754 + orf19.1471 289361 290754 2 289361|289895 289574|290754 289905 290378 COX4 orf19.9046|IPF25835.1|IPF20017.1|Contig4-3015_0013|orf6.7102|CA4533|CaO19.9046|CaO19.1471 Protein described as subunit IV of cytochrome c oxidase; transcription is regulated by Mig1p; macrophage/pseudohyphal-induced gene; macrophage-induced protein; repressed by nitric oxide: intron in 5'-UTR [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr2 291061 292250 + orf19.1473 291061 292250 1 291061 292250 291132 292226 orf19.9048|IPF25790.1|IPF4386.1|Contig4-3015_0011|orf6.7100|CA4532|CaO19.1473|CaO19.9048|IPF4386 Predicted ORF in Assemblies 19, 20 and 21; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 292450 296359 + orf19.1474 292450 296359 1 292450 296359 292480 296253 SLA1 orf19.9049|IPF25863.1|IPF4392.1|Contig4-3015_0009|orf6.7099|CA4531|CaO19.9049|CaO19.1474 Predicted ORF in Assemblies 19, 20 and 21; transcription is regulated by Nrg1p and Mig1p; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 296573 298204 + orf19.1476 296573 298204 1 296573 298204 296573 298204 orf19.9051|IPF25770.1|IPF4394.1|Contig4-3015_0008|orf6.7097|CA4530|IME4|CaO19.9051|CaO19.1476 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 297970 298931 - orf19.1477 297970 298931 1 298931 297970 298785 298207 orf19.9052|IPF25812.1|IPF4395.1|Contig4-3015_0007|orf6.7096|CA4529|CaO19.9052|CaO19.1477|IPF4395 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 298964 301526 - orf19.1478 298964 301526 1 301526 298964 301509 299254 orf19.9053|IPF25749.1|IPF4396.1|Contig4-3015_0004|Contig4-3015_0005|orf6.7095|CA4528|CaO19.1478|STT3|CaO19.9053 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 301748 304474 - orf19.1479 301748 304474 1 304474 301748 304222 301880 orf19.9054|IPF4398.3|IPF29400.1|Contig4-3015_0002|orf6.2103|orf6.7094|CA4527|CaO19.1479|IPF4398|IPF4398.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 305429 306209 + orf19.1480 305429 306209 1 305429 306209 305492 306022 orf19.9055|IPF25808.1|IPF4401.2|Contig4-2219_0007|orf6.2104|CA0903|CaO19.1480|CaO19.9055|IPF4401 Protein described as succinate dehydrogenase, enzyme of citric acid cycle; downregulated by Efg1p; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 306188 308965 - orf19.1481 306188 308965 1 308965 306188 308924 306408 HAP42 orf19.9056|IPF25743.1|IPF4403.2|Contig4-2219_0003|Contig4-2219_0005|orf6.2105|CA0904|CaO19.1481|CaO19.9056|IPF4403 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 309613 310350 + orf19.1482 309613 310350 1 309613 310350 309760 310080 orf19.9057|IPF25838.1|IPF4405.1|Contig4-2219_0002|orf6.2106|CA0905|CaO19.9057|CaO19.1482|IPF4405 Predicted ORF in Assemblies 19, 20 and 21; expression regulated during planktonic growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 310024 310685 - orf19.1483 310024 310685 1 310685 310024 310614 310219 orf19.9058|IPF25853.1|IPF4406.2|Contig4-2219_0001|orf6.2107|CA0906|CaO19.9058|CaO19.1483|IPF4406 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 310743 311702 + orf19.1484 310743 311702 1 310743 311702 310886 311644 orf19.9059|IPF25804.1|IPF19889.1|Contig4-2638_0001|orf6.2108|CA0907|CaO19.9059|CaO19.1484|IPF19889 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 311626 312247 - orf19.1485 311626 312247 1 312247 311626 312166 311825 orf19.9060|IPF6016.2|Contig4-2638_0003|orf6.2109|CA0908|MRPL31|CaO19.9060|CaO19.1485 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 314224 315476 - orf19.1486 314224 315476 1 315476 314224 315173 314676 orf19.9061|IPF6011.2|IPF6010.3|Contig4-2638_0008|orf6.2256|CA1000|CaO19.9061|CaO19.1486|IPF6011 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 316830 317209 - ntar_313 316830 317209 1 317209 316830 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 322081 323268 - orf19.1488 322081 323268 1 323268 322081 323268 322609 orf19.9065|IPF6006.2|IPF29419.1|Contig4-2801_0001|orf6.2260|CA1001|CaO19.1488|CaO19.9065|IPF6006 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr2 323401 323519 - tl(caa)1 323401 323519 2 323519|323444 323481|323401 tL(CAA)1.2 tRNA-Leu predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 327044 327316 + ntar_314 327044 327316 1 327044 327316 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 327699 332303 + orf19.1490 327699 332303 1 327699 332303 327699 331928 MSB2 orf19.9067|IPF25849.1|IPF6003.1|Contig4-2801_0007|orf6.2804|CA1345|CaO19.9067|CaO19.1490|IPF6003 Mucin family member, possible sensor of cell wall damage; required for Cek1p phosphorylation in response to cell wall stress; transcription is negatively regulated by Rim101p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr2 332538 332819 + ntar_315 332538 332819 1 332538 332819 332542 332712 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 333010 333297 + orf19.1490.1 333010 333297 1 333010 333297 333010 333297 Predicted ORF in retrotransposon Tca16 with similarity to the Gag-Pol region of retrotransposons; added to Assembly 21 based on comparative genome analysis; overlaps orf19.1490.2, which is annotated as blocked reading frame [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 334106 336093 - orf19.1491 334106 336093 1 336093 334106 336020 334176 orf19.9068|IPF14405.2|IPF5991.3|Contig4-2801_0010|orf6.1460|orf6.2805|CA0492|CaO19.1491|SNU71 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 336175 338557 + orf19.1492 336175 338557 1 336175 338557 336574 338541 PRP39 orf19.9069|IPF25748.1|IPF14401.2|Contig4-2358_0005|orf6.1461|CA0493|CA6189|PRP39.5f|CaO19.9069|CaO19.1492|PRP39.3f|PRP39.3 Putative component of the U1 snRNP, involved in splicing; ortholog of S. cerevisiae PRP39; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 338488 340616 - orf19.1493 338488 340616 1 340616 338488 340557 338599 RAD7 orf19.9070|IPF14400.2|IPF16848.2|Contig4-2358_0001|orf6.1462|orf6.936|CA0494|CaO19.1493 Protein similar to S. cerevisiae Rad7p, which is a subunit of the Nucleotide Excision Repair Factor 4; induced under hydroxyurea treatment [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 341120 342877 + orf19.1494 341120 342877 2 341120|341491 341305|342877 341240 342678 RAD23 orf19.9071|IPF25788.1|IPF16846.2|Contig4-2358_0003|orf6.935|CA0231|CaO19.1494 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 342710 343698 - orf19.1495 342710 343698 1 343698 342710 343631 342834 orf19.9072|IPF16638.1|IPF19099.1|Contig4-2358_0004|orf6.3546|orf6.934|CA1860|UTR4|CaO19.1495 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 343808 344435 + ntar_316 343808 344435 1 343808 344435 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 343891 345349 - orf19.1496 343891 345349 1 345349 343891 345349 343994 orf19.9073|IPF19614.1|IPF19615.1|orf6.933|orf6.3545|CA1859|CaO19.1496|IPF19614.3f|IPF19614 Putative transcription factor with zinc finger DNA-binding motif; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr2 345494 346830 - orf19.1497 345494 346830 1 346830 345494 346606 345494 ZCF6|IPF19100.2|CA6255|CaO19.1497|IPF19614.5f Putative transcription factor with zinc cluster DNA-binding motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr2 350120 354286 + orf19.1499 350120 354286 1 350120 354286 350731 354165 CTF1 orf19.9075|IPF25868.1|IPF15240.2|Contig4-2582_0009|orf6.3543|CA6190|CaO19.9075|CaO19.1499|IPF15240 Putative zinc-finger transcription factor, similar to A. nidulans FarA and FarB; activates genes required for fatty acid degradation; induced by oleate; null mutant displays carbon source utilization defects and slightly reduced virulence [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 354220 355901 - orf19.1500 354220 355901 1 355901 354220 355815 354292 orf19.9076|IPF15344.2|IPF15343.3|Contig4-2650_0016|orf6.3542|CA1858|CaO19.1500|IPF15344 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 356077 357425 + orf19.1502 356077 357425 1 356077 357425 356131 356898 orf19.9078|IPF25801.1|IPF15345.3|Contig4-2650_0014|orf6.192|orf6.3540|CA0028|CaO19.1502|IPF15345|IPF15345.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 357258 360070 - orf19.1504 357258 360070 1 360070 357258 359972 357411 orf19.9080|IPF15348.2|IPF29398.1|Contig4-2650_0011|orf6.193|orf6.3538|CA1857|CaO19.1504|IPF15348 Putative patatin-like phospholipase; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 360753 362170 - orf19.1505 360753 362170 1 362170 360753 361937 360900 orf19.9081|IPF13689|IPF13689.2|IPF18995.2|Contig4-2650_0009|orf6.1309|orf6.3537|CA1856|CaO19.1505 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 364198 364623 - orf19.1506 364198 364623 1 364623 364198 364623 364198 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 365004 367152 - orf19.1507 365004 367152 1 367152 365004 367058 365082 orf19.9083|IPF25758.1|IPF17676.2|Contig4-1513_0004|Contig4-2650_0001|Contig4-2650_0018|orf6.1307|CA0411|CaO19.9083|AMN1|CaO19.1507|IPF17676 Predicted ORF in Assemblies 19, 20 and 21; Plc1p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 367250 367602 - orf19.1508 367250 367602 1 367602 367250 367585 367250 IPF29448.1|orf6.1306|CaO19.1508 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr2 367329 367837 + ntar_317 367329 367837 1 367329 367837 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 368671 369526 + ntar_318 368671 369526 1 368671 369526 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 369834 373022 - orf19.1509 369834 373022 1 373022 369834 372659 369888 ROD1 orf19.9084|IPF19576.1|IPF19577.1|Contig4-1782_0002|orf6.344|orf6.3960|CA2177|CaO19.1509 Protein not essential for viability; similar to S. cerevisiae Rod1p, which is a membrane protein with a role in drug tolerance; repressed by Rgt1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 374066 374427 + ntar_319 374066 374427 1 374066 374427 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 374394 376731 - orf19.1510 374394 376731 1 376731 374394 376459 374579 orf19.9085|IPF9282|IPF25762.1|IPF9282.2|Contig4-1782_0005|orf6.3961|CA2178|CaO19.9085|CaO19.1510 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 377896 386454 - orf19.1513 377896 386454 1 386454 377896 385840 377966 FAB1 orf19.9088|IPF9288.2|IPF29418.1|Contig4-2754_0006|Contig4-2754_0007|Contig4-2754_0009|orf6.3964|CA2179|CaO19.1513 Phosphatidylinositol 3-phosphate 5-kinase; required for hyphal growth on solid media, and for wild-type vacuolar morphology and acidification; not required for wild-type virulence in mouse systemic infection or for adherence to HeLa cells [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 386646 388098 + orf19.1514 386646 388098 1 386646 388098 386900 387922 orf19.9089|IPF9290.2|IPF8244.2|Contig4-1806_0003|Contig4-2754_0001|orf6.3399|orf6.3965|CA2180|IPF9290|CaO19.1514 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 387877 389456 - orf19.1515 387877 389456 1 389456 387877 389302 388136 CHT4 orf19.9090|IPF25787.1|IPF8245.2|Contig4-1806_0001|orf6.3398|orf6.3966|CA1753|CaO19.1515|IPF8245 Chitinase; similar to S. cerevisiae sporulation-specific Cts2p; functionally complements A. gossypii cts2 mutant sporulation defect; homozygous null mutation causes no obvious defects; transcription decreases upon yeast-to-hyphal switch [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 388279 388882 + ntar_320 388279 388882 1 388279 388882 388327 388470 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 389105 389328 + ntar_321 389105 389328 1 389105 389328 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 389524 392183 + orf19.1516 389524 392183 1 389524 392183 389652 392036 orf19.9091|IPF17697.2|IPF8246.2|Contig4-2807_0008|orf6.3397|orf6.3967|CA1752|UBP14|CaO19.1516 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 391983 392343 - ntar_322 391983 392343 1 392343 391983 392141 391983 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 392570 393940 + orf19.1517 392570 393940 2 392570|392835 392721|393940 392667 393895 ARO3 orf19.9092|orf6.3396|IPF25795.1|IPF8248.2|Contig4-2807_0007|CA1751|CaO19.1517|CaO19.9092|ARO3.exon2 3-Deoxy-D-arabinoheptulosonate-7-phosphate synthase; enzyme of aromatic amino acid biosynthesis; GCN-regulated; feedback-inhibited by phenylalanine when heterologously produced in S. cerevisiae; Aro3p and Aro4p catalyze the same reaction [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 394154 397753 + orf19.1519 394154 397753 1 394154 397753 394340 397642 orf19.9094|IPF25872.1|IPF8252.2|Contig4-2807_0006|orf6.3394|CA1750|CaO19.1519|CaO19.9094|IPF8252 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 397731 401368 - orf19.1522 397731 401368 1 401368 397731 401241 398113 orf19.9097|IPF25875.1|IPF8257.2|Contig4-2807_0004|orf6.1171|orf6.3391|CA1748|CaO19.1522|IPF8257.5f|IPF8257 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 402438 404124 - orf19.1523 402438 404124 1 404124 402438 404124 402466 FMO1 orf19.9098|IPF15750.2|IPF15749.3|Contig4-2017_0003|orf6.1172|orf6.3390|CA0348|CaO19.1523|IFK1 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to toxic ergosterol analog, and to amphotericin B [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr2 405578 407053 + orf19.1524 405578 407053 1 405578 407053 405578 407053 SPR3 orf19.9100|IPF15746.3|IPF16732.2|Contig4-1766_0002|Contig4-2017_0004|orf6.1173|orf6.1204|CA0363|CaO19.1524 [NOT TRANSCRIBED?] Septin; mutant has no obvious phenotype [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 407366 407909 + ntar_323 407366 407909 1 407366 407909 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 408121 409779 + orf19.1525 408121 409779 1 408121 409779 408210 409406 orf19.9101|IPF18883.2|IPF15983.2|Contig4-2444_0002|orf6.1205|orf6.1860|CA0364|CaO19.1525|NMD4|IPF15983 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 410141 415541 + orf19.1526 410141 415541 1 410141 415541 410274 415346 SNF2 orf19.9102|IPF15319.2|IPF15980.3|Contig4-2444_0006|Contig4-2444_0007|orf6.1206|orf6.1859|CA0747|CaO19.1526 Protein involved in transcriptional regulation; ortholog of S. cerevisiae Snf2p, which is the catalytic subunit of the SWI/SNF chromatin remodeling complex; interacts with Swi1p; SWI/SNF complex is essential for hyphal growth and virulence [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 415435 416174 - orf19.1527 415435 416174 1 416174 415435 416069 415515 orf19.9103|IPF25813.1|IPF14921.2|Contig4-2467_0002|orf6.1858|CA0746|CaO19.9103|CaO19.1527|IPF14921 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 416463 417780 + orf19.1528 416463 417780 1 416463 417780 416571 417626 orf19.9104|IPF14920.2|IPF29413.1|Contig4-2467_0004|Contig4-2467_0005|orf6.1857|CA0745|MTF1|CaO19.9104|CaO19.1528 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 417866 418894 - orf19.1529 417866 418894 1 418894 417866 418894 417866 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 418987 419508 - orf19.1530 418987 419508 1 419508 418987 419508 418987 IPF29422.1|CA6256|CaO19.1530|IPF14919.5f [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 419619 422319 - orf19.1531 419619 422319 1 422319 419619 422123 419748 orf19.9106|IPF25746.1|IPF16839.3|Contig4-2467_0008|orf6.1855|orf6.931|CA0743|RNA14|CaO19.1531|RNA14.3eoc|IPF14917.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 422880 424448 + orf19.1532 422880 424448 1 422880 424448 422927 423997 orf19.9107|IPF25786.1|IPF17420.2|Contig4-2467_0011|orf6.932|CA0230|CaO19.1532|TOM37 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 423934 424068 - ntar_324 423934 424068 1 424068 423934 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 424554 424733 + ntar_325 424554 424733 1 424554 424733 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 424930 426716 + orf19.1533 424930 426716 1 424930 426716 425071 426447 orf19.9108|IPF15116.1|IPF17419.2|Contig4-1607_0002|orf6.839|CA0201|CaO19.1533|IPF17419|IPF15116 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 426198 426342 - ntar_326 426198 426342 1 426342 426198 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 426988 429418 + orf19.1534 426988 429418 1 426988 429418 427404 429179 orf19.9109|orf6.1064|IPF15119.2|IPF19059.2|orf6.838|CA0200|CaO19.1534|ZRT3|IPF15119 Protein similar to S. cerevisiae Zrt3p, which is a transporter of zinc ions; predicted Kex2p substrate [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 429228 430625 - orf19.1535 429228 430625 1 430625 429228 430444 429650 orf19.9110|IPF25803.1|IPF14392.2|Contig4-2088_0007|orf6.1063|CA0285|CaO19.9110|CaO19.1535|IPF14392 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 429638 429846 + ntar_327 429638 429846 1 429638 429846 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 432334 434724 + orf19.1536 432334 434724 1 432334 434724 433195 434631 orf19.9111|IPF19060.1|Contig4-2088_0003|orf6.1061|orf6.1062|orf6.2308|CA6257|CA1030|orf19.1537|ZRC.5f Putative protein of unknown function, required for normal filamentous growth; mRNA binds to She3p and is localized to hyphal tips; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 434600 436190 - orf19.1538 434600 436190 1 436190 434600 436109 434841 TLG2 orf19.9112|IPF14397.2|IPF29411.1|Contig4-2088_0010|orf6.2307|CA1029|CaO19.1538 Predicted ORF in Assemblies 19, 20 and 21; macrophage/pseudohyphal-repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 437457 438834 - orf19.1539 437457 438834 1 438834 437457 438826 437627 orf19.9113|IPF25782.1|IPF6488.2|Contig4-2381_0006|orf6.2306|CA1028|CaO19.9113|CaO19.1539|IPF6488 Predicted ORF in Assemblies 19, 20 and 21; highly induced upon biofilm formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 442660 446680 - orf19.1541 442660 446680 1 446680 442660 446421 443524 orf19.9115|IPF6493|IPF18788.2|IPF6493.2|Contig4-2847_0017|Contig4-2847_0018|orf6.2304|orf6.821|CA0193|CaO19.1541 Protein not essential for viability; transcription is repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 447781 447970 + ntar_328 447781 447970 1 447781 447970 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 448714 450664 - orf19.1542 448714 450664 1 450664 448714 450618 448810 HEX3 orf19.9116|IPF25764.1|IPF6497.2|Contig4-2847_0014|orf6.6400|CA3970|CaO19.1542|CaO19.9116|IPF6497 Protein similar to S. cerevisiae Hex3p, which is involved in DNA damage response; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 450891 451382 + ntar_329 450891 451382 1 450891 451382 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 451305 453032 - orf19.1543 451305 453032 1 453032 451305 452791 451490 OPI1 orf19.9117|orf6.6401|IPF6498|IPF25784.1|IPF6498.2|Contig4-2847_0013|CA3971|CaO19.1543|CaO19.9117 Functional homolog of S. cerevisiae Opi1p, which is a transcriptional repressor of INO1 involved in inositol biosynthesis; has leucine zipper and putative Opi1-Sin3 interaction domain; interacts with ScSin3p, but not CaSin3p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 455561 456598 + orf19.1544 455561 456598 1 455561 456598 455598 456395 orf19.9118|IPF6504.2|IPF29417.1|Contig4-2788_0007|Contig4-2847_0005|orf6.6402|CA3972|CaO19.1544|CaO19.9118|IPF6504 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 456417 457023 - orf19.1545 456417 457023 1 457023 456417 456971 456504 orf19.9119|IPF25834.1|IPF6505.2|Contig4-2847_0004|orf6.6403|CA3973|MRPS8|CaO19.9119|CaO19.1545|IPF6505 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 457203 458210 + orf19.1546 457203 458210 1 457203 458210 457283 458161 orf19.9120|IPF25799.1|IPF6507.2|Contig4-2847_0002|orf6.6404|CA3974|CaO19.1546|FMP39|CaO19.9120|IPF6507 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 458133 459087 - orf19.1547 458133 459087 1 459087 458133 459087 458182 orf19.9121|IPF25796.1|IPF20152.1|Contig4-2847_0001|orf6.6405|CA3975|PNK1|CaO19.9121|CaO19.1547|IPF20152 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr2 459116 459915 + orf19.1548 459116 459915 1 459116 459915 459139 459870 orf19.9122|IPF25806.1|IPF15310.2|orf6.6406|CA3976|CaO19.1548|SNU23|CaO19.9122 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 460126 461241 + orf19.1549 460126 461241 1 460126 461241 460292 461038 orf19.9123|IPF25802.1|IPF20153.1|Contig4-2092_0006|orf6.6407|CA3977|CaO19.9123|CaO19.1549|IPF20153 Predicted ORF in Assemblies 19, 20 and 21; repressed by nitric oxide; identified in detergent-resistant membrane fraction (possible lipid raft component); predicted transmembrane helix [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 461216 461949 - orf19.1552 461216 461949 1 461949 461216 461919 461344 CPR3 orf19.9126|IPF25810.1|IPF20154.1|Contig4-2092_0004|orf6.6410|CA3978|CaO19.9126|CaO19.1552 Protein described as a peptidyl-prolyl cis-trans isomerase; macrophage-induced protein; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 461669 462172 + orf19.1551 461669 462172 1 461669 462172 461669 462172 orf19.9125|IPF25828.1|IPF20155.1|Contig4-2163_0001|orf6.6409|CaO19.9125|CaO19.1551 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 462279 464062 - orf19.1553 462279 464062 2 464062|463716 463803|462279 463878 462431 ENT3 orf19.9127|IPF25779.1|IPF25794.1|IPF25744.1|IPF7129.2|IPF7127.2|IPF7128.2|Contig4-2092_0009|Contig4-2163_0004|orf6.6411|CA3979|ENT3.3f Putative protein of unknown function, induced during the mating process; transcription is upregulated in an RHE model of oral candidiasis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 464446 468369 - orf19.1555 464446 468369 1 468369 464446 468209 464538 SAC3 orf19.9129|IPF7130.2|IPF29415.1|IPF18010.3|Contig4-2824_0019|Contig4-2824_0021|orf6.355|orf6.6413|CA6258|CA3982|orf19.1556|SAC3.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 468494 469436 - orf19.1557 468494 469436 1 469436 468494 469414 468572 orf19.9130|IPF7133.1|IPF19325.2|Contig4-2824_0012|Contig4-2824_0014|orf6.356|orf6.6414|CA3983|CaO19.1557|IPF7133|IPF7133.3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 469476 470788 - orf19.1559 469476 470788 1 470788 469476 470709 469612 HOM2 orf19.9132|IPF7136.1|IPF29412.1|Contig4-2824_0011|orf6.6416|CA3984|CaO19.1559 Putative aspartate-semialdehyde dehydrogenase; fungal-specific (no human or murine homolog); ketoconazole-repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 471192 473090 + orf19.1560 471192 473090 1 471192 473090 471244 472860 POB3 orf19.9133|IPF25771.1|IPF7138.2|Contig4-2824_0009|orf6.6417|CA3985|CaO19.1560|CaO19.9133 Protein similar to S. cerevisiae Pob3p, which is involved in chromatin assembly and disassembly; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 474452 475259 + orf19.1562 474452 475259 1 474452 475259 474686 475228 orf19.9135|IPF25811.1|IPF7141.1|Contig4-2824_0006|orf6.6419|CA3986|CaO19.9135|CaO19.1562|IPF7141 Predicted ORF in Assemblies 19, 20 and 21; transcription is repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 476533 478377 + orf19.1563 476533 478377 1 476533 478377 476654 478294 ECM3 orf19.9136|IPF25768.1|IPF7144.2|Contig4-2824_0004|orf6.6420|CA3987|CaO19.1563|CaO19.9136 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 477018 477342 - ntar_330 477018 477342 1 477342 477018 477342 477097 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 477408 477724 - ntar_331 477408 477724 1 477724 477408 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 478523 479524 + orf19.1564 478523 479524 1 478523 479524 478694 479263 orf19.9137|IPF25819.1|IPF7145.2|Contig4-2824_0002|orf6.6421|CA3988|CaO19.9137|CaO19.1564|IPF7145 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 479286 481270 - orf19.1565 479286 481270 1 481270 479286 481184 479343 orf19.9138|IPF25756.1|IPF7147.2|Contig4-2824_0022|orf6.6422|CA3989|DUS3|CaO19.1565|CaO19.9138|IPF7147 Putative transcription factor with zinc finger DNA-binding motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 481329 484290 + orf19.1566 481329 484290 1 481329 484290 481408 484236 UTP21 orf19.9139|IPF25737.1|IPF14782.2|Contig4-2110_0005|Contig4-2110_0006|orf6.6423|CA3990|CaO19.1566|CaO19.9139|IPF14782 Predicted ORF in Assemblies 19, 20 and 21; physically interacts with TAP-tagged Nop1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 484461 487769 + orf19.1567 484461 487769 1 484461 487769 484560 487664 orf19.9140|orf19.9141|IPF25780.1|IPF25769.1|IPF19794.1|IPF14783.2|Contig4-2110_0002|Contig4-2110_0004|orf6.6424|orf6.6425|CA3991|CA3992|orf19.1568|VAM6.5f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 487721 491580 - orf19.1569 487721 491580 1 491580 487721 491423 487896 UTP22 orf19.9142|IPF8275.2|IPF29445.1|Contig4-2925_0002|Contig4-2925_0003|Contig4-2925_0005|orf6.6426|CA3993|CaO19.1569|IPF8275 Predicted ORF in Assemblies 19, 20 and 21; decreased expression observed in an ssr1 homozygous null mutant; decreased expression in response to prostaglandins; heterozygous null mutant exhibits resistance to parnafungin [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 491802 494207 + orf19.1570 491802 494207 1 491802 494207 491866 494052 ERG7 orf19.9143|IPF8270.1|IPF19258.2|Contig4-2925_0007|orf6.480|orf6.6427|CA3994|CaO19.1570 2,3-epoxysqualene-lanosterol cyclase (lanosterol synthase), catalyzes the conversion of 2,3-oxidosqualene to lanosterol in sterol biosynthesis; fluconazole-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 494311 495161 - orf19.1571 494311 495161 2 495161|494723 494792|494311 495161 494311 orf19.9144|orf19.9145|IPF18269.2|IPF25857.1|IPF8269.2|IPF8268.2|Contig4-2925_0009|Contig4-2925_0010|orf6.479|orf6.6428|orf6.478|CA0091|orf19.1572|IPF8268|CA0092|IPF8268.3f [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 496197 496270 + tv(aac)1 496197 496270 1 496197 496270 tV(AAC)1.2 tRNA-Val predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 496613 500809 - orf19.1573 496613 500809 1 500809 496613 500706 496654 orf19.9146|IPF8267.2|IPF29441.1|Contig4-2925_0014|orf6.1885|orf6.477|CA0761|CaO19.1573|IPF8267 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 501095 503058 + orf19.1574 501095 503058 1 501095 503058 501240 503006 orf19.9147|IPF15686.2|IPF29407.1|Contig4-2925_0020|orf6.1886|CA0762|TAF7|CaO19.1574|TAF67 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 503216 504463 + orf19.1575 503216 504463 1 503216 504463 503401 504363 PRS1 orf19.9148|IPF15685.2|IPF9631.1|PRS3|Contig4-2410_0006|orf6.1887|orf6.5345|CA3168|CaO19.1575 Phosphoribosylpyrophosphate synthetase; enzyme of purine, pyrimidine, histidine, and tryptophan biosynthesis; essential; flucytosine induced; macrophage/pseudohyphal-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 504678 507226 + orf19.1576 504678 507226 1 504678 507226 504784 506652 orf19.9149|IPF25763.1|IPF9632.2|Contig4-2410_0005|orf6.5344|CA3167|CaO19.1576|CaO19.9149|IPF9632 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 507756 509084 + orf19.1577 507756 509084 1 507756 509084 507756 509084 orf19.9150|IPF25781.1|IPF9634.1|Contig4-3005_0030|orf6.5343|CA3166|CaO19.1577|CaO19.9150|IPF9634 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 509403 514738 + orf19.1578 509403 514738 1 509403 514738 509452 514620 orf19.9151|IPF25824.1|IPF9638.2|Contig4-3005_0028|Contig4-3005_0029|orf6.5342|CA3165|CaO19.1578|RRP5|CaO19.9151|FMI1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 514703 517117 - orf19.1580 514703 517117 1 517117 514703 517088 514977 orf19.9153|IPF25755.1|IPF13187.2|Contig4-3005_0023|Contig4-3005_0025|orf6.5340|CA3164|YFW3|CaO19.1580|CaO19.9153|IPF13187 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 515743 515920 + ntar_332 515743 515920 1 515743 515920 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 517722 518054 + orf19.1581 517722 518054 1 517722 518054 517722 518054 orf19.9154|IPF29446.1|orf6.5339|CaO19.9154|CaO19.1581 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 519117 520844 + orf19.1582 519117 520844 2 519117|519780 519713|520844 519117 520844 orf19.9155|orf19.9156|IPF25814.1|IPF25792.1|IPF13183.2|IPF13181.2|Contig4-3005_0018|Contig4-3005_0019|orf6.5337|orf6.5338|CA3163|CA3162|orf19.1583|HOL5.5f Predicted membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS); mRNA binds to She3p [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 519694 520848 - ntar_333 519694 520848 1 520848 519694 519953 519786 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 521081 522796 + orf19.1584 521081 522796 1 521081 522796 521169 522701 orf19.9157|IPF25774.1|IPF13121.2|Contig4-3005_0016|orf6.5336|CA3161|CaO19.9157|CaO19.1584|IPF13121.3 Predicted membrane transporter, member of the monocarboxylate porter (MCP) family, major facilitator superfamily (MFS); shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 521217 522463 - ntar_334 521217 522463 1 522463 521217 521584 521444 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 522989 523305 - ntar_335 522989 523305 1 523305 522989 523305 523063 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 523979 525370 + orf19.1585 523979 525370 1 523979 525370 524084 525196 ZRT2 orf19.9158|IPF25789.1|IPF13128.2|Contig4-3005_0008|orf6.5335|CA3160|CaO19.1585|CaO19.9158 Protein described as predicted zinc transporter; ciclopirox olamine, fluconazole, or alkaline downregulated; transcriptionally induced by interaction with macrophage; amphotericin B induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 525603 526490 - orf19.1586 525603 526490 1 526490 525603 526490 525603 FGR22 orf19.9159|IPF25798.1|IPF13130.2|PLC3|PLC2|Contig4-3005_0005|orf6.5334|CA3159|PLC22|CaO19.9159|CaO19.1586 Putative phosphatidylinositol-specific phospholipase C (PI-PLC); predicted type 2 membrane protein; no S. cerevisiae ortholog; role in, and regulated by, filamentation; no mouse systemic virulence role; almost identical to orf19.5797 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr2 526890 528401 - orf19.1587 526890 528401 1 528401 526890 528401 526890 HGT20 orf19.9160|IPF25777.1|IPF13131.2|Contig4-3005_0004|orf6.5333|CA3158|CaO19.9160|CaO19.1587|IPF13131.3 Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; regulated by Nrg1p [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr2 529017 529937 + orf19.1588 529017 529937 1 529017 529937 529140 529559 orf19.9161|IPF25850.1|IPF14456.2|Contig4-3005_0003|orf6.5332|CA3157|CaO19.9161|FMP21|CaO19.1588|IPF14456 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 529990 532049 + orf19.1589 529990 532049 1 529990 532049 530098 531411 orf19.9162|IPF25783.1|IPF14455.1|Contig4-3005_0002|orf6.5331|CA3156|RRN7|CaO19.9162|CaO19.1589|IPF14455 Putative DNA-binding transcription factor [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 531829 533492 - orf19.1589.1 531829 533492 1 533492 531829 533492 532131 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr2 534851 535636 - orf19.5842 534851 535636 1 535636 534851 535636 534851 orf19.13264|IPF21411.1|IPF11219.2|orf6.6136|CaO19.5842|CaO19.13264 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 536236 537079 + orf19.5841 536236 537079 1 536236 537079 536271 537029 orf19.13263|IPF21413.1|IPF11221.1|Contig4-2921_0007|orf6.6137|CA3779|CaO19.5841|CaO19.13263|IPF11221 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 536773 537520 - orf19.5840 536773 537520 1 537520 536773 537520 537026 orf19.13262|IPF21420.1|IPF11222.1|Contig4-2921_0006|orf6.6138|CA3780|CaO19.13262|CaO19.5840|IPF11222 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr2 537556 538748 + orf19.5839 537556 538748 1 537556 538748 537582 538676 PDR17 orf19.13261|IPF21403.1|IPF11224.2|Contig4-2921_0005|orf6.6139|CA3781|CaO19.5839|CaO19.13261|IPF11224 Predicted ORF in Assemblies 19, 20 and 21; role in sensitivity to fluconazole, specifically; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 538971 540044 + orf19.5838 538971 540044 1 538971 540044 539009 539914 orf19.13260|IPF21408.1|IPF11225.2|Contig4-2921_0004|orf6.6140|CA3782|SER2|CaO19.13260|CaO19.5838 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 539874 540917 - orf19.5837 539874 540917 1 540917 539874 540881 539988 orf19.13259|IPF21405.1|IPF11226.1|Contig4-2921_0003|orf6.6141|CA3783|CaO19.5837|CaO19.13259|IPF11226 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 540951 541974 - orf19.5835 540951 541974 1 541974 540951 541905 541063 orf19.13257|IPF21410.1|IPF11229.1|Contig4-2921_0001|orf6.6143|CA3784|RRP7|CaO19.13257|CaO19.5835|IPF11229 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 542214 545426 + orf19.5834 542214 545426 1 542214 545426 542346 545354 orf19.13256|IPF21443.1|IPF19788.1|orf6.6144|CA3785|SXM1|CaO19.5834|CaO19.13256|IPF19788 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 545674 546892 + orf19.5833 545674 546892 1 545674 546892 545705 546796 orf19.13255|IPF21394.1|IPF14267.1|Contig4-1905_0003|orf6.6145|CA3786|CaO19.13255|UFD1|CaO19.5833 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 546784 547743 - orf19.5832 546784 547743 1 547743 546784 547558 546917 HPT1 orf19.13254|IPF21416.1|IPF14266.2|Contig4-1905_0001|orf6.6146|CA3787|CaO19.5832|CaO19.13254 Protein abundance is affected by URA3 expression in the CAI-4 strain background; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 548198 549514 - orf19.5831 548198 549514 1 549514 548198 549514 548198 orf19.13253|IPF21393.1|IPF16445.1|Contig4-1906_0002|orf6.6147|CA3788|CaO19.13253|CaO19.5831|IPF16445 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 549778 550115 - ntar_336 549778 550115 1 550115 549778 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 550316 553303 + orf19.5830 550316 553303 1 550316 553303 550397 553195 orf19.13252|orf6.6148|IPF11217.2|IPF27925.1|Contig4-2543_0002|CA3789|CaO19.5830|LHS1|CaO19.13252|IPF11217 Protein similar to S. cerevisiae Hsp70p; predicted Kex2p substrate [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 553488 555726 + orf19.5828 553488 555726 1 553488 555726 553526 555679 orf19.13250|IPF11215.2|IPF27906.1|Contig4-2543_0003|orf6.6150|CA3790|UAF1|CaO19.5828|IPF11215 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 555368 556697 - orf19.5827 555368 556697 1 556697 555368 556659 555715 BUB2 orf19.13249|IPF11212|IPF21407.1|IPF11212.2|Contig4-2543_0004|orf6.6151|CA3791|CaO19.5827|CaO19.13249 Predicted ORF in Assemblies 19, 20 and 21; described as similar to S. cerevisiae Bub2p; mutation confers hypersensitivity to amphotericin B; induced upon adherence to polystyrene; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 557037 558713 - orf19.5826 557037 558713 1 558713 557037 558713 557079 orf19.13248|IPF21388.1|IPF11211.2|Contig4-2543_0005|orf6.6152|CA3792|CaO19.13248|UGA41|CaO19.5826|UGA5 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr2 560216 560828 + orf19.5825.1 560216 560828 1 560216 560828 560291 560581 IPF21439.1|IPF5701.2|Contig4-2711_0001|CA3793|IPF5701 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 560614 561414 - orf19.5825 560614 561414 1 561414 560614 561278 560829 orf19.13247|IPF21425.1|IPF5700.2|Contig4-2711_0003|orf6.6153|CA3794|NCB2|CaO19.13247|CaO19.5825 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 561832 563185 - orf19.5824 561832 563185 1 563185 561832 563093 562032 orf19.13246|IPF21404.1|IPF5699.2|Contig4-2711_0004|orf6.6154|CA3795|CaO19.5824|CaO19.13246|IPF5699 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 563327 564698 - orf19.5823 563327 564698 1 564698 563327 564635 563601 SGT2 orf19.13245|IPF21399.1|IPF5697.2|Contig4-2711_0006|orf6.6155|CA3796|CaO19.5823|CaO19.13245 Protein abundance is affected by URA3 expression in the CAI-4 strain background; transcription is regulated by Mig1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 564850 568512 - orf19.5821 564850 568512 1 568512 564850 568512 564943 orf19.13243|IPF21436.1|IPF5693.2|Contig4-2711_0009|orf6.6157|CA3797|CaO19.5821|CaO19.13243|IPF5633|IPF5623 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr2 570159 571793 + orf19.5820 570159 571793 1 570159 571793 570159 571793 UGA6 orf19.13242|IPF5691.3|IPF27909.1|Contig4-2836_0014|orf6.4039|orf6.6158|CA3798|UGA42|CaO19.5820|CA2224|UGA6.3eoc|IPF19944.1 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21; decreased transcription is observed upon benomyl treatment or in an azole-resistant strain that overexpresses MDR1 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 572682 574229 + orf19.5818 572682 574229 1 572682 574229 573007 574035 SUR2 orf19.13240|IPF21401.1|IPF5688.1|Contig4-2836_0010|orf6.4041|CA2225|CaO19.13240|CaO19.5818 Protein described as similar to ceramide hydroxylase; predicted enzyme of sphingolipid biosynthesis; upregulated in biofilm; regulated by Tsa1p, Tsa1Bp under H2O2 stress conditions [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 574368 575399 + orf19.5817 574368 575399 2 574368|574563 574483|575399 574430 575084 orf19.13239|IPF21419.1|IPF5686.1|Contig4-2836_0009|orf6.4042|CA2226|BET3.3f|BET3.exon2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 575254 576711 - orf19.5816 575254 576711 1 576711 575254 576539 575361 EBP7 orf19.13238|IPF21400.1|IPF5684.2|Contig4-2836_0008|orf6.4043|CA2227|CaO19.5816|OYE25|CaO19.13238 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to toxic ergosterol analog; oxidative stress-induced via Cap1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 577696 580215 + orf19.5815 577696 580215 1 577696 580215 577904 580060 SCT2 orf19.13237|IPF21381.1|IPF5683.2|Contig4-2836_0004|orf6.4044|CA2228|CaO19.5815|GPT2|CaO19.13237|SCT12 Putative glycerol-3-phosphate acyltransferase; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 580474 581113 + orf19.5814 580474 581113 1 580474 581113 580643 580993 orf19.13236|IPF21435.1|IPF5682.2|orf6.4045|CA2229|CaO19.5814|CaO19.13236|IPF5682 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 581161 581507 - ntar_337 581161 581507 1 581507 581161 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 581910 582540 + ntar_338 581910 582540 1 581910 582540 582058 582321 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 582476 582806 - ntar_339 582476 582806 1 582806 582476 582698 582546 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 583104 584223 + orf19.5813 583104 584223 1 583104 584223 583289 583846 orf19.13235|IPF9302.3|IPF27912.1|Contig4-2152_0007|orf6.4046|orf6.6647|CA4164|CaO19.5813|IPF9302|IPF9302.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 584119 585565 - orf19.5812 584119 585565 1 585565 584119 585527 584262 orf19.13234|IPF21397.1|IPF9301.2|Contig4-2152_0009|orf6.6646|CA4163|CaO19.13234|CaO19.5812|IPF9301 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 586227 587981 + orf19.5811 586227 587981 1 586227 587981 586227 587912 MET1 orf19.13233|IPF21386.1|IPF9300.2|Contig4-2921_0008|orf6.6645|CA4162|CaO19.5811|CaO19.13233 Putative uroporphyrin-3 C-methyltransferase; enzyme of methionine biosynthesis; upregulated in the presence of human whole blood or polymorphonuclear (PMN) cells; Hog1p-induced; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr2 588097 589795 + orf19.5809 588097 589795 1 588097 589795 588237 589598 orf19.13231|IPF21392.1|IPF20164.1|Contig4-2921_0009|orf6.6643|CA4161|IPF20164 Putative arylformamidase, enzyme of the NAD biosynthesis pathway; Gcn4p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr2 589627 591219 - orf19.5808 589627 591219 1 591219 589627 591139 589898 orf19.13230|IPF21395.1|IPF9294.2|Contig4-2921_0011|orf6.6642|CA4160|CaO19.5808|CaO19.13230|IPF9294 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr2 591395 593023 - orf19.5806 591395 593023 1 593023 591395 592987 591488 ALD5 orf19.13228|YER73|IPF17030.2|IPF27910.1|Contig4-2921_0012|orf6.6640|CA4159|ALD99|CaO19.5806 Protein described as an aldehyde dehydrogenase; decreased expression in fluconazole-resistant isolate, or in hyphae; biofilm induced;fluconazole-downregulated; protein abundance is affected by URA3 expression in the CAI-4 strain background [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 595086 597296 - orf19.5805 595086 597296 1 597296 595086 597148 595394 DLD1 orf19.13227|IPF21387.1|IPF10287.2|DLD3|Contig4-3045_0019|Contig4-3045_0023|orf6.6639|CA4158|CaO19.13227|CaO19.5805 Putative D-lactate dehydrogenase; transcription is specific to white cell type; shows colony morphology-related gene regulation by Ssn6p; transcription is upregulated in both intermediate and mature biofilms [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 597427 601625 - orf19.5804 597427 601625 1 601625 597427 601474 597563 HYU1 orf19.13226|IPF21434.1|IPF10288.2|Contig4-3045_0016|Contig4-3045_0017|orf6.6638|CA4157|CaO19.5804|CaO19.13226 Protein described as hydantoin utilization protein A; induced upon adherence to polystyrene; regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 601840 603199 - orf19.5802 601840 603199 1 603199 601840 603138 602098 orf19.13224|IPF21402.1|IPF10990.2|Contig4-3045_0015|orf6.6636|CA4156|CaO19.13224|CaO19.5802|IPF10990 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 603312 604942 - orf19.5801 603312 604942 1 604942 603312 604784 603543 RNR21 orf19.13223|IPF21396.1|IPF10991.2|Contig4-3045_0013|orf6.6635|CA4155|RNR2|CaO19.5801|CaO19.13223 Protein described as similar to ribonucleoside-diphosphate reductase; regulated by tyrosol and cell density; transcription is upregulated in response to treatment with ciclopirox olamine; fluconazole or flucytosine induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 606064 608846 - orf19.5799 606064 608846 1 608846 606064 608308 606248 orf19.13221|IPF21383.1|IPF20010.1|Contig4-3045_0009|orf6.6633|CA4154|CaO19.13221|CaO19.5799|IPF20010 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 609577 610382 + ntar_340 609577 610382 1 609577 610382 609732 609872 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 610754 613853 + orf19.5798 610754 613853 1 610754 613853 610758 613544 LIG4 orf19.13220|CDC9|IPF21371.1|IPF6823.2|Contig4-3045_0005|orf6.6632|CA4153|CaO19.13220|CaO19.5798|DNLI DNA ligase; mRNA detected in yeast-form and pseudohyphal cells, induced upon hyphal induction; suppresses S. cerevisiae ime1-1 mutant IME2 transcription defect; required for wild-type filamentous growth and wild-type pathogenesis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 613916 615114 + orf19.5797 613916 615114 1 613916 615114 614063 614950 PI-PLC orf19.13219|IPF21406.1|IPF17332.2|PLC2|Contig4-3045_0004|orf6.6631|CA4152|CA6227|PLC2.5f|CaO19.5797|PLC21|CaO19.13219|PLC2.3f Phosphatidylinositol (PtdIns)-specific phospholipase C (PI-PLC); predicted type 2 membrane protein; role in, and regulated by, filamentation, Nrg1p and Tup1p; no mouse systemic virulence role; orf19.5797 and orf19.1586 are almost identical [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 615116 616792 + orf19.5796 615116 616792 1 615116 616792 615116 616690 SHE9 orf19.13218|IPF21389.1|IPF6829.2|Contig4-3045_0003|orf6.6630|CA4151|CaO19.13218|CaO19.5796 Protein with similarity to S. cerevisiae She9p, which inhibits growth when overproduced; gene has possible growth-regulation element; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr2 616909 618314 + orf19.5793 616909 618314 1 616909 618314 616968 618203 PR26 orf19.13215|IPF21398.1|IPF6830.2|Contig4-3045_0002|orf6.6627|CA4150|CaO19.13215|RPT3|CaO19.5793 Protein with similarity to proteasomal 26S regulatory subunit of S. cerevisiae, H. sapiens, Methanobacterium thermoautotrophicum (Archaebacterium) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 618205 619816 - orf19.5792 618205 619816 1 619816 618205 619788 618292 SMP3 orf19.13214|IPF21390.1|IPF6831.2|Contig4-3045_0001|orf6.6626|CA4149|CaO19.5792|CaO19.13214 Mannosyltransferase of glycosylphosphatidylinositol (GPI) biosynthesis; catalyzes mannosylation of Man3-GPI precursor; essential for viability; 8-9 transmembrane regions predicted; has HQEXRF motif; functional homolog of S. cerevisiae Smp3p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 620864 622185 + orf19.5791 620864 622185 1 620864 622185 620950 622059 IDH2 orf19.13213|orf6.6625|IPF6833.2|IPF27911.1|Contig4-2708_0009|CA4148|CaO19.5791 Protein described as isocitrate dehydrogenase subunit; transcription is upregulated in response to treatment with ciclopirox olamine; transcriptionally regulated by iron; expression greater in high iron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 622069 623357 - orf19.5789 622069 623357 1 623357 622069 623036 622218 ADE8 orf19.13211|IPF17327.2|IPF6835.1|Contig4-2708_0008|orf6.4861|orf6.6623|CA4147|CaO19.5789 Predicted enzyme of amino acid biosynthesis; upregulated in biofilm; S. cerevisiae ortholog is Gcn4p regulated; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr2 623561 626411 + orf19.5788 623561 626411 2 623561|623796 623595|626411 623592 626320 EFT2 orf19.13210|IPF17326.3|IPF6840.1|EFT2-1|Contig4-2708_0006|orf6.4860|orf6.6622|CA2810 Elongation Factor 2 (eEF2); GTPase; essential; highly expressed; target of sordarin antifungals; antigenic in human, mouse; lacks site for regulatory phosphorylation by eEF2 kinase; GCN-regulated; complements S. cerevisiae eft1 eft2 mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 627689 627864 + ntar_341 627689 627864 1 627689 627864 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 628082 629291 + orf19.5785 628082 629291 1 628082 629291 628280 629158 orf19.13207|IPF21409.1|IPF16515.2|Contig4-2708_0001|orf6.4857|CaO19.5785|CaO19.13207 Predicted ORF in Assemblies 19, 20 and 21; greater mRNA abundance observed in a cyr1 or ras1 homozygous null mutant than in wild type; induced by nitric oxide; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 630688 632949 + orf19.5784 630688 632949 1 630688 632949 630791 632920 orf19.13206|IPF11969.2|Contig4-2695_0010|orf6.4856|CA2809|CaO19.5784|AMO1|CaO19.13206 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 633116 634071 + orf19.5783 633116 634071 1 633116 634071 633143 633763 orf19.13205|IPF21418.1|IPF11966.2|Contig4-2695_0008|orf6.4855|CA2808|CaO19.5783|CaO19.13205|IPF11966 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 633819 636339 - orf19.5782 633819 636339 1 636339 633819 636276 634021 orf19.13204|IPF21375.1|IPF11965.2|Contig4-2695_0007|orf6.4854|CA2807|CaO19.5782|CaO19.13204|IPF11965 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 636461 638737 - orf19.5780 636461 638737 1 638737 636461 638608 636587 orf19.13202|IPF21380.1|IPF11702.2|Contig4-2695_0005|orf6.4852|CA2806|CaO19.13202|CaO19.5780|IPF11702 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 639257 642054 - orf19.5779 639257 642054 1 642054 639257 642004 639440 RNR1 orf19.13201|orf6.4851|IPF21372.1|IPF11704.2|Contig4-2695_0002|Contig4-2973_0004|CA2805|CaO19.5779|CaO19.13201 Protein similar S. cerevisiae Rnr1p, large subunit of ribonucleotide reductase; expression greater in low iron; transposon mutation affects filamentous growth; farnesol upregulated in biofilm; regulated by cell cycle, tyrosol, cell density [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 642827 643277 - ntar_342 642827 643277 1 643277 642827 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 643399 644282 + orf19.5777 643399 644282 1 643399 644282 643501 644211 orf19.13199|IPF21412.1|IPF19961.1|Contig4-2973_0002|orf6.4849|CA2804|CaO19.13199|CaO19.5777|IPF19961 Predicted ORF in Assemblies 19, 20 and 21; induced upon biofilm formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 644227 654222 - orf19.5776 644227 654222 1 654222 644227 654222 644362 TOM1 orf19.13198|orf19.8529|orf19.8530|IPF21369.1|IPF11711.2|IPF26413.1|IPF26466.1|IPF18528.2|IPF4563.2|Contig4-3099_0044|Contig4-3099_0045|orf6.3949|orf6.3950|orf6.4848|CA2803|CA2169|CA2170|orf19.911|orf19.912|CaO19.13198|CaO19.5776|IPF11711 Predicted ORF in Assemblies 19, 20 and 21; transcription is regulated by Nrg1p and Mig1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr2 654708 654982 + ntar_343 654708 654982 1 654708 654982 654824 654976 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 655482 656976 + orf19.910 655482 656976 1 655482 656976 655606 656946 orf19.8528|IPF26426.1|IPF4558.1|Contig4-3099_0042|orf6.3948|CA2168|PRP3|CaO19.8528|CaO19.910|IPF4558 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 655546 655734 - ntar_344 655546 655734 1 655734 655546 655728 655561 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 657141 657767 + orf19.909.1 657141 657767 3 657141|657357|657600 657235|657505|657767 657188 657627 Predicted ORF in Assembly 20 and 21; gene has intron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 657854 658320 - ntar_345 657854 658320 1 658320 657854 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 658915 660287 - orf19.909 658915 660287 1 660287 658915 660121 658991 STP4 orf19.8527|IPF26436.1|IPF4553.2|Contig4-3099_0038|orf6.3947|CA2167|CaO19.8527|CaO19.909|IPF4553 Putative transcription factor with zinc finger DNA-binding motif; induced in core caspofungin response; shows colony morphology-related gene regulation by Ssn6p; induced by 17-beta-estradiol, ethynyl estradiol [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 663080 663580 + ntar_346 663080 663580 1 663080 663580 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 663495 664781 - orf19.908 663495 664781 1 664781 663495 664628 663750 FEN12 orf19.8526|IPF18186.2|IPF4547.2|Contig4-3099_0035|orf6.3945|orf6.3946|orf6.7270|CA2166|orf19.907|FEN99|CaO19.908 Predicted ORF in Assemblies 19, 20 and 21; amphotericin B, caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 665206 669700 - orf19.906 665206 669700 1 669700 665206 669665 665520 ROM2 orf19.8525|IPF26481.1|IPF4544.1|Contig4-3099_0031|orf6.7271|CA4668|CaO19.906|CaO19.8525 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 670052 670252 + ntar_347 670052 670252 1 670052 670252 670082 670252 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 672760 674206 + orf19.905 672760 674206 1 672760 674206 672821 674143 AVT7 orf19.8524|IPF26427.1|IPF4537.1|Contig4-3099_0028|orf6.7272|CA4669|CaO19.8524|CaO19.905|IPF4537 Predicted ORF in Assemblies 19, 20 and 21; similar to S. cerevisiae Avt7p; downregulated upon adherence to polystyrene; constitutive expression independent of MTL or white-opaque status [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 674314 675314 + orf19.904 674314 675314 1 674314 675314 674364 675065 orf19.8523|IPF26452.1|IPF4536.1|Contig4-3099_0027|orf6.7273|CA4670|CaO19.904|CaO19.8523|IPF4536 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 675856 676725 + orf19.903 675856 676725 1 675856 676725 675910 676656 GPM1 orf19.8522|IPF26449.1|IPF4535.2|GPM1-1|Contig4-3099_0022|orf6.7274|CA4671|CaO19.903|CaO19.8522 Surface protein that binds host complement Factor H and FHL-1; phosphoglycerate mutase; antigenic in murine, human infection; biofilm-, fluconazole-, or amino acid starvation (3-aminotriazole treatment) induced, farnesol-downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 676992 679374 + orf19.900 676992 679374 1 676992 679374 677135 679291 orf19.8519|IPF26399.1|IPF3659.2|Contig4-3099_0020|orf6.7277|CA4672|NSP1|CaO19.900|CaO19.8519|IPF3659 Predicted ORF in Assemblies 19, 20 and 21; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 679574 680568 + orf19.899 679574 680568 1 679574 680568 679664 680512 orf19.8518|IPF26445.1|IPF3661.2|Contig4-3099_0019|orf6.7278|CA4673|CaO19.899|CaO19.8518|IPF3661 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 680766 682194 + orf19.898 680766 682194 1 680766 682194 681030 682055 HEM2 orf19.8517|orf6.8517|IPF26438.1|IPF3663.2|Contig4-3099_0017|orf6.7279|CA4674|CaO19.8517|CaO19.898 Protein described as porphobilinogen synthase; transcriptionally regulated by iron; expression greater in high iron; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 680970 681151 - ntar_348 680970 681151 1 681151 680970 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 681531 681849 - ntar_349 681531 681849 1 681849 681531 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 682047 683030 - orf19.897 682047 683030 1 683030 682047 682866 682216 orf19.8516|IPF26446.1|IPF3664.2|Contig4-3099_0016|orf6.7280|CA4675|CaO19.897|CaO19.8516|IPF3664 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 684001 691486 + orf19.896 684001 691486 1 684001 691486 684001 691416 CHK1 orf19.8515|orf6.7978|HK1|IPF26451.1|IPF3668.2|Contig4-3099_0013|Contig4-3099_0015|orf6.7281|CA4676|CaO19.8515|CaO19.896 Histidine kinase involved in a two-component signaling pathway that regulates cell wall biosynthesis; disruption impairs hyphal development and decreases virulence in mouse intravenous (but not rat vaginal) infection [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr2 684022 684317 - ntar_350 684022 684317 1 684317 684022 684180 684022 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 684595 684792 - ntar_351 684595 684792 1 684792 684595 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 691404 692948 - orf19.895 691404 692948 1 692948 691404 692680 691547 HOG1 orf19.8514|IPF26431.1|IPF3669.2|Contig4-3099_0012|orf6.7282|CA4677|CaO19.8514|CaO19.895 MAP kinase of osmotic-, heavy metal-, and core stress response; role in regulation of glycerol, D-arabitol in response to stress; phosphorylated in response to H2O2 (Ssk1p-dependent) or NaCl; mutant induces protective mouse immune response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 693076 695527 + orf19.894 693076 695527 1 693076 695527 693076 695166 orf19.8513|IPF26401.1|IPF3670.2|Contig4-3099_0008|Contig4-3099_0010|orf6.7283|CA4678|RGP1|CaO19.8513|CaO19.894|IPF3670 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr2 695656 697658 + orf19.893 695656 697658 1 695656 697658 695838 697511 PGA17 orf19.8512|IPF26415.1|IPF3674.2|Contig4-3099_0006|orf6.7284|CA4679|CaO19.8512|CaO19.893|IPF3674 Putative GPI-anchored protein of unknown function; exogenously expressed protein is a substrate for Kex2p processing in vitro; transcription is repressed in response to alpha pheromone in SpiderM medium; macrophage-induced gene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 698160 700749 + orf19.891 698160 700749 1 698160 700749 698222 700558 orf19.8510|IPF26387.1|IPF3677.1|Contig4-3099_0004|orf6.7286|CA4680|AMD1|CaO19.891|CaO19.8510 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 700893 702539 + orf19.889 700893 702539 1 700893 702539 700893 702539 THI20 orf19.8508|IPF26412.1|IPF3679.2|Contig4-3099_0003|orf6.7288|CA4681|CaO19.8508|CaO19.889|IPF3679 Putative phosphomethylpyrimidine kinase; also described as a putative transcription factor with TENA DNA-binding motif; fungal-specific (no human or murine homolog) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 702305 702535 - ntar_352 702305 702535 1 702535 702305 702535 702392 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 702743 707164 + orf19.886 702743 707164 1 702743 707164 702830 707023 PAN1 orf19.8505|IPF26482.1|IPF3687.2|Contig4-3099_0002|orf6.7292|CA4682|CaO19.8505|CaO19.886|IPF3687 Essential protein involved in endocytosis and polarized growth; similar to S. cerevisiae Pan1p, which is a part of a complex that regulates actin cytoskeleton [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 707072 709855 - orf19.882 707072 709855 1 709855 707072 709618 707180 HSP78 orf19.8501|orf19.8503|IPF26442.1|IPF26425.1|IPF9007.2|IPF9010.2|Contig4-2772_0009|Contig4-2772_0010|orf6.7293|orf6.7295|CA4684|CA4683|orf19.884|HSP78.5f Protein described as a heat-shock protein; transcriptionally regulated by macrophage response; transcription is regulated by Nrg1p, Mig1p, Gcn2p, Gcn4p, Mnl1p; heavy metal (cadmium) stress-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 709950 712259 - orf19.881 709950 712259 1 712259 709950 711992 710277 DFG16 orf19.8500|IPF9013|IPF18185.2|IPF9013.2|Contig4-2772_0008|orf6.7296|CA4685|CaO19.8500|CaO19.881 Protein of the Rim101p pathway that regulates filamentation in response to alkaline pH; required for host tissue invasion during infection; similar to S. cerevisiae Dfg16p that acts in Rim101p processing [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 712629 715967 + orf19.880 712629 715967 1 712629 715967 712772 715804 orf19.8499|IPF26508.1|IPF9015.2|Contig4-2772_0004|Contig4-2772_0005|orf6.7297|CA4686|CaO19.880|SFB3|CaO19.8499|IPF9015 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 715751 718245 - orf19.879 715751 718245 1 718245 715751 718203 715876 orf19.8498|IPF26393.1|IPF9017.2|Contig4-2772_0003|orf6.7298|CA4687|SHE4|CaO19.8498|CaO19.879|IPF9017 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 718327 719319 + orf19.878 718327 719319 1 718327 719319 718377 719273 NBN1 orf19.8497|IPF26440.1|IPF9018.2|Contig4-2772_0001|orf6.7299|CA4688|YNG2|CaO19.878|CaO19.8497 Subunit of the NuA4 histone acetyltransferase complex; Plc1p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 719592 720473 + orf19.876 719592 720473 1 719592 720473 719652 720392 PGA33 orf19.8495|IPF9020.2|IPF29660.1|Contig4-2937_0001|orf6.7301|CA4689|CaO19.876|IPF9020 Putative GPI-anchored protein of unknown function; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 720723 722076 + orf19.875 720723 722076 1 720723 722076 720723 721982 orf19.8494|IPF3959.2|IPF29654.1|Contig4-2937_0004|orf6.7302|CA4690|CaO19.875|IPF3959 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr2 721930 723253 - orf19.874 721930 723253 1 723253 721930 723193 722087 orf19.8493|IPF26430.1|IPF3958.1|Contig4-2937_0005|orf6.7303|CA4691|CaO19.874|CaO19.8493|IPF3958 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 723575 724554 - orf19.873.1 723575 724554 2 724554|724098 724175|723575 724341 723813 COX6 IPF26503.1|IPF26395.1|IPF3955.2|IPF3954.2|Contig4-2937_0006|COX6.3 Flucytosine induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 724957 725316 - orf19.873 724957 725316 1 725316 724957 725316 724957 orf19.8492|IPF26486.1|IPF29678.1|Contig4-2937_0011|orf6.7304|CaO19.8492|CaO19.873 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 725313 726730 - orf19.872 725313 726730 1 726730 725313 726593 725313 orf19.8491|IPF26423.1|IPF3952.1|Contig4-2937_0012|orf6.7305|CA4693|CaO19.872|SFP1|CaO19.8491|IPF3952 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 728216 731678 + orf19.871 728216 731678 1 728216 731678 728433 731492 orf19.8490|IPF3950.2|IPF29698.1|Contig4-2937_0019|orf6.2459|orf6.7306|CA4694|LST4|CaO19.871|IPF3950 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 731991 732127 + ntar_353 731991 732127 1 731991 732127 731991 732119 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 740206 740658 + ntar_354 740206 740658 1 740206 740658 740362 740484 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 740632 742717 - orf19.868 740632 742717 1 742717 740632 742466 740829 ADAEC orf19.8487|IPF3937.2|IPF3935.3|Contig4-2634_0003|orf6.2588|orf6.72|CA1203|CaO19.868|IPF3937 Transcription is specific to white cell type [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 747165 749044 + orf19.867 747165 749044 1 747165 749044 747283 748896 orf19.8486|IPF14524.2|IPF17850.2|Contig4-2449_0003|orf6.2589|orf6.3547|orf6.567|CA1204|CaO19.867|IPF14524 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 749592 751861 + orf19.866 749592 751861 1 749592 751861 749879 751801 RAD32 orf19.8485|IPF14521.2|IPF15212.1|Contig4-2942_0014|orf6.2590|orf6.3548|CA1861|RAD30|CaO19.866 Protein similar to S. cerevisiae protein with role in nucleotide excision repair; down-regulation associated with azole resistance [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 751046 755100 - orf19.864 751046 755100 1 755100 751046 755005 751901 orf19.8483|IPF26501.1|IPF7641.2|Contig4-2942_0012|Contig4-2942_0013|orf6.3550|CA1862|NMD2|CaO19.864|CaO19.8483 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 755197 756484 - orf19.863 755197 756484 1 756484 755197 756454 755318 orf19.8482|IPF26428.1|IPF7643.1|Contig4-2942_0011|orf6.3551|CA1863|CaO19.863|MRPL35|CaO19.8482 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 756651 757622 - orf19.862 756651 757622 1 757622 756651 757498 756788 orf19.8481|IPF26453.1|IPF7644.2|Contig4-2942_0009|orf6.3552|CA1864|CaO19.862|CaO19.8481|IPF7644 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 757676 758095 + ntar_355 757676 758095 1 757676 758095 757802 758041 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 757944 759063 - orf19.861 757944 759063 1 759063 757944 758733 758203 orf19.8480|IPF26462.1|IPF7646.2|Contig4-2942_0008|orf6.3553|CA1865|CaO19.8480|CaO19.861|IPF7646 Predicted transcriptional regulator with bZip domain [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 759478 761991 + orf19.860 759478 761991 1 759478 761991 759544 761628 BMT8 orf19.8479|IPF17595.2|IPF7647.2|Contig4-2942_0006|orf6.1229|orf6.3554|CA1866|CaO19.860|WRY3|IPF7647 Putative beta-mannosyltransferase, member of a 9-gene family that includes characterized genes BMT1, BMT2, BMT3, and BMT4 with roles in beta-1,2-mannosylation of cell wall phosphopeptidomannan; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 763170 765270 + orf19.857 763170 765270 1 763170 765270 763501 765159 FMO2 orf19.8477|IPF18598.2|IPF18599.1|Contig4-2942_0002|orf6.1227|orf6.3555|CA6181|CA1867|orf19.859|IFK3.3f|CA0374|IFK3|IPF7651.2 Predicted ORF in Assemblies 19, 20 and 21; expression regulated during planktonic growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 766053 766194 - ntar_356 766053 766194 1 766194 766053 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 766380 768321 + orf19.856 766380 768321 1 766380 768321 766651 768309 IFK2 orf19.8476|IPF26414.1|IPF11973.1|Contig4-2541_0011|orf6.1905|orf6.3556|CA0775|FMO3|CaO19.856|CA0373|IPF7655.5eoc|IPF7655.2 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 768528 769277 + orf19.855 768528 769277 1 768528 769277 768528 769277 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 769641 771404 + orf19.854 769641 771404 1 769641 771404 769797 771101 UGA11 orf19.8474|IPF26422.1|IPF26397.1|IPF11975.1|IPF11976.1|Contig4-2541_0008|orf6.1903|CA0773|orf19.853.3|UGA11.5f|UGA11.exon1 Predicted ORF in Assemblies 19, 20 and 21; macrophage-induced gene; overlaps orf19.854.1, which is a region annotated as a blocked reading frame [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 771813 771884 + te(cuc)1 771813 771884 1 771813 771884 tE(CUC)1.2 tRNA-Glu predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 773165 774423 + orf19.853 773165 774423 1 773165 774423 773182 774273 SAP99 orf19.8473|orf6.1902|IPF26434.1|IPF11977.3|Contig4-2541_0002|CA0771|CaO19.853|IPF11977|IPF11977.2 Putative secreted aspartyl protease; possible Kex2p substrate; transcriptionally regulated by iron; expression greater in low iron; repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 775114 776741 + orf19.852 775114 776741 1 775114 776741 775519 776613 SAP98 orf19.8472|IPF26435.1|IPF14031.2|Contig4-2545_0002|orf6.1542|CA0549|CaO19.852|IPF14031|IPF14031.1 Predicted ORF in Assemblies 19, 20 and 21; regulated by Gcn2p and Gcn4p; expressed in opaque MTLa/MTLa cells [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 776681 779482 - orf19.851 776681 779482 1 779482 776681 779482 776966 orf19.8471|orf6.1543|IPF26385.1|IPF14030.2|Contig4-2545_0003|Contig4-2545_0006|CA0550|MNN42|CaO19.8471|CaO19.851|IPF14030 Protein of unknown function; transcription is negatively regulated by Rim101p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr2 782160 783852 + orf19.850 782160 783852 1 782160 783852 782312 783436 orf19.8470|IPF14821.1|IPF29657.1|Contig4-2545_0010|orf6.1044|CA0275|CaO19.850|NTA1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 785985 788531 + orf19.849 785985 788531 1 785985 788531 785985 788531 orf19.8469|IPF19106.2|IPF19522.1|orf6.1043|orf6.900|orf6.3745|MNN4|CA0217|MNN41|CaO19.849 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 789616 789939 + orf19.848 789616 789939 1 789616 789939 789616 789939 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 790263 790335 + tr(ucu)2 790263 790335 1 790263 790335 tR(UCU)2.2 tRNA-Arg predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 790342 790429 + tf(gaa)2 790342 790429 2 790342|790394 790378|790429 tF(GAA)2.2 tRNA-Phe predicted by tRNAscan-SE; has atypical tertiary T15A48 basepair (rather than R15Y48 basepair) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 791026 792374 + orf19.847 791026 792374 1 791026 792374 791079 792167 YIM1 orf19.8467|IPF3415.2|IPF29656.1|IPF3415|Contig4-2477_0005|orf6.3747|CA2016|CaO19.847|CaO19.8467 Protein similar to protease of mitochondrial inner membrane; increased transcription is observed upon benomyl treatment; macrophage-downregulated gene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 792299 795434 - orf19.846 792299 795434 1 795434 792299 795282 792391 orf19.8466|IPF26381.1|IPF3414.2|Contig4-2477_0006|Contig4-2729_0002|orf6.3748|CA2017|CaO19.8466|CaO19.846|IPF3414 Predicted ORF in Assemblies 19, 20 and 21; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 795625 798374 - orf19.844 795625 798374 1 798374 795625 798201 795727 STE11 orf19.8464|IPF26388.1|IPF3412.2|Contig4-2729_0006|orf6.3750|CA2018|CaO19.844|CaO19.8464 Predicted ORF in Assemblies 19, 20 and 21; similar to S. cerevisiae Ste11p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr2 798530 800894 - orf19.843 798530 800894 1 800894 798530 800845 798659 orf19.8463|IPF3409.2|IPF29645.1|Contig4-2729_0007|orf6.3751|CA2019|CaO19.8463|CaO19.843|IPF3409 Putative DNA repair exonuclease; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 801054 801628 - orf19.842 801054 801628 1 801628 801054 801591 801181 ASR3 orf19.8462|IPF16901.1|IPF3408.3|Contig4-2729_0008|orf6.3752|orf6.3853|CA2020|CaO19.842|IPF16901 Gene regulated by cAMP and by osmotic stress; greater mRNA abundance observed in a cyr1 or ras1 homozygous null mutant than in wild type; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr2 801949 804164 - orf19.841 801949 804164 1 804164 801949 804110 802020 orf19.8461|IPF26400.1|IPF3406.3|Contig4-2739_0006|orf6.3753|orf6.3852|CA2093|CaO19.841|IPF3406|IPF3406.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 804324 805395 - orf19.840 804324 805395 2 805395|804973 805304|804324 805314 804502 RPL21A orf19.8460|IPF19037.2|IPF3404.2|Contig4-2739_0007|orf6.1127|orf6.3851|CA2092|RPL21A.3 Putative ribosomal protein; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 805606 806906 - orf19.838.1 805606 806906 2 806906|806362 806851|805606 806857 805800 RPS9B IPF3402.2|IPF29662.1|Contig4-2739_0010|orf6.1126|CA0322 Predicted ribosomal protein; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage; possibly transcriptionally regulated upon hyphal formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 807083 809054 + orf19.839 807083 809054 1 807083 809054 807091 809031 orf19.8458|IPF16075.2|IPF3401.1|Contig4-2676_0017|Contig4-2676_0019|Contig4-2739_0012|orf6.1125|orf6.3850|CA2091|CaO19.839|IPF3401 Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide in yhb1 mutant; mutation confers hypersensitivity to aureobasidin A [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr2 809036 809787 - orf19.837.1 809036 809787 2 809787|809423 809508|809036 809639 809163 INO4 Transcriptional activator that may be involved in regulation of ribosomal protein genes; forms a heterodimer with Ino2p; related to S. cerevisiae Ino4p; gene has intron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 810413 810485 + tr(ucu)3 810413 810485 1 810413 810485 tR(UCU)3.2 tRNA-Arg predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 810492 810579 + tf(gaa)3 810492 810579 2 810492|810544 810528|810579 tF(GAA)3.2 tRNA-Phe predicted by tRNAscan-SE; has atypical tertiary T15A48 basepair (rather than R15Y48 basepair) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 810814 811735 + orf19.837 810814 811735 1 810814 811735 811096 811545 GNA1 orf19.8457|IPF26470.1|IPF3395.2|Contig4-2676_0011|orf6.3848|CA2089|CaO19.837|CaO19.8457 Glucosamine-6-phosphate acetyltransferase; enzyme of UDP-GlcNAc biosynthesis; required for viability in absence of GlcNAc supplementation; required for persistent infection and wild-type virulence in mouse systemic infection [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 811191 812299 - orf19.836.1 811191 812299 4 812299|812048|811817|811712 812121|811902|811785|811191 812147 811695 IPF26402.1|IPF3394.2|CA2088|IPF3394 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 812313 813740 + orf19.836 812313 813740 1 812313 813740 812380 813492 orf19.8456|orf6.3847|IPF26429.1|IPF3393.2|Contig4-2676_0008|CA2087|CaO19.8456|CaO19.836|IPF3393 Protein likely to be essential for growth, based on an insertional mutagenesis strategy [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 813422 816080 - orf19.835 813422 816080 1 816080 813422 815909 813549 orf19.8455|IPF26392.1|IPF3392.2|Contig4-2676_0003|Contig4-2676_0006|orf6.3846|CA2086|CaO19.8455|CaO19.835|IPF3392 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 816304 819003 - orf19.834 816304 819003 1 819003 816304 818868 816340 orf19.8454|IPF26384.1|IPF3388.2|Contig4-2676_0001|orf6.3845|CA2085|CaO19.8454|CaO19.834|IPF3388 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 819163 822665 - orf19.832 819163 822665 1 822665 819163 822416 819369 GPI13 orf19.8452|orf19.8453|IPF26461.1|IPF16059.3|IPF3385.1|IPF3384.1|Contig4-2493_0001|Contig4-2493_0002|orf6.3843|orf6.3844|orf6.6723|CA2083|CA2084|orf19.833|IPF3384.5f Protein of major facilitator superfamily; has phosphodiesterase/nucleotide pyrophosphatase domain; similar to S. cerevisiae Gpi13p, which acts in GPI anchor biosynthesis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 822937 824690 - orf19.831 822937 824690 1 824690 822937 824624 823077 orf19.8451|IPF26420.1|IPF16057.2|Contig4-2493_0006|orf6.6722|CA4228|CaO19.831|CaO19.8451|IPF16057 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr2 823477 823741 + ntar_357 823477 823741 1 823477 823741 823477 823644 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 825226 828104 - orf19.829 825226 828104 1 828104 825226 827890 825527 SCH9 orf19.8449|IPF26391.1|IPF13426.2|Contig4-2493_0008|Contig4-2913_0014|orf6.6720|CA4227|CaO19.8449|CaO19.829 Protein required for chlamydospore formation and for embedded hyphal growth, not essential for viability; similar to S. cerevisiae Sch9p, which is a protein kinase involved in growth control [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 830475 831383 + orf19.828 830475 831383 1 830475 831383 830516 831313 orf19.8448|IPF26441.1|IPF8752.2|Contig4-2913_0009|orf6.6719|CA4226|MRPL24|CaO19.8448|CaO19.828|IPF8752 Predicted ORF in Assemblies 19, 20 and 21; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 830973 831378 - ntar_358 830973 831378 1 831378 830973 831378 831232 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 831628 832679 + orf19.827.1 831628 832679 2 831628|832122 831696|832679 831684 832408 RPL39 IPF26380.1|IPF8753.2|Contig4-2913_0008|CA4225|RPL39.3 Ribosomal protein L39; transcription is induced upon germ tube formation; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 832702 834487 + orf19.827 832702 834487 2 832702|833507 833425|834487 832828 833565 orf19.8447|IPF26456.1|IPF8755.2|Contig4-2913_0007|orf6.6718|CA4224|CaO19.827|CaO19.8447|IPF8755 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 834005 836034 - orf19.826 834005 836034 1 836034 834005 835946 834090 orf19.8446|IPF26408.1|IPF8757.2|Contig4-2913_0006|orf6.6717|CA4223|CaO19.8446|CaO19.826|IPF8757 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 836113 837425 + orf19.825 836113 837425 1 836113 837425 836207 837304 GCD7 orf19.8445|IPF26437.1|IPF8759.2|Contig4-2913_0005|orf6.6716|CA4222|CaO19.8445|CaO19.825 Protein described as a translation initiator; downregulated in the presence of human whole blood or polymorphonuclear (PMN) cells [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 837333 838001 - orf19.823 837333 838001 1 838001 837333 838001 837333 orf19.8443|IPF26454.1|IPF8760.2|Contig4-2913_0004|orf6.6714|CA4221|CaO19.823|CaO19.8443|IPF8760 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 838164 838760 - orf19.822 838164 838760 1 838760 838164 838760 838191 orf19.8442|IPF26460.1|IPF8762.2|Contig4-2913_0002|orf6.6713|CA4220|CaO19.822|CaO19.8442|IPF8762 Protein detected in some, not all, biofilm extracts; fluconazole-downregulated; greater mRNA abundance observed in cyr1 or ras1 homozygous null mutant than in wild type; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr2 838971 840416 - orf19.820 838971 840416 1 840416 838971 840282 839158 SDS22 orf19.8440|IPF26433.1|IPF8765.2|Contig4-2913_0001|orf6.6711|CA4219|CaO19.820|CaO19.8440 Predicted ORF in Assemblies 19, 20 and 21; macrophage/pseudohyphal-repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 840427 841198 - orf19.819 840427 841198 1 841198 840427 841148 840816 orf19.8439|IPF26496.1|IPF8766.2|orf6.6710|CA4218|CaO19.8439|ACP11|CaO19.819|ACP1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 841363 846741 - orf19.816 841363 846741 1 846741 841363 846741 841435 DCK2 orf19.8436|IPF26463.1|IPF5809.2|orf6.6707|YLR422W-2|CA4217|CaO19.8436|CaO19.816|IPF5809 Predicted ORF in Assemblies 19, 20 and 21; similar to S. cerevisiae Ylr422wp; transposon mutation affects filamentous growth; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 847468 853447 - orf19.815 847468 853447 1 853447 847468 853403 847659 DCK1 orf19.8435|IPF5806.2|IPF29663.1|Contig4-2714_0002|Contig4-2714_0003|orf6.45|orf6.6706|YLR422W|CA4216|CaO19.8435|CaO19.815|IPF5806 Putative guanine nucleotide exchange factor required for embedded filamentous growth; activates Rac1p; contains a DOCKER domain; similar to adjacent DCK2 and to S. cerevisiae Ylr422wp; regulated by Nrg1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 854355 854631 + ntar_359 854355 854631 1 854355 854631 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 854615 857549 - orf19.814 854615 857549 1 857549 854615 857429 854787 SSY1 orf19.8434|CSY1|IPF5802.2|IPF29641.1|IPF29694.1|Contig4-2714_0007|orf6.6705|SSY1.5|CA4215|orf19.814.3|CaO19.814 Amino acid sensor, required for wild-type hyphal growth on solid serum or Lees media, but not for hyphal growth under all conditions; similar to S. cerevisiae Ssy1p aa sensor and to aa permeases; 12 predicted membrane spanning regions [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 857832 858046 - snrnau2 857832 858046 1 858046 857832 Highly conserved U2 small nuclear RNA involved in splicing; ortholog of S. cerevisiae LSR1 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 858640 860858 + orf19.813 858640 860858 1 858640 860858 858692 860770 orf19.8433|IPF26404.1|IPF5799.1|Contig4-2861_0006|orf6.6704|YLR106|CA6180|CaO19.8433|CaO19.813|IPF26404 Predicted ORF in Assemblies 19, 20 and 21; not essential for viability; oxidative stress-induced via Cap1p; similar to S. cerevisiae Vhs3p, which is a putative phosphopantothenoylcysteine decarboxylase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 861107 862480 + orf19.812 861107 862480 1 861107 862480 861107 862480 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 862641 863981 + orf19.811 862641 863981 1 862641 863981 862641 863777 orf19.8431|IPF5795|IPF26432.1|IPF5795.2|Contig4-2861_0003|orf6.6702|CA4213|CaO19.811|CaO19.8431 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr2 863809 864082 - ntar_360 863809 864082 1 864082 863809 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 864311 868181 + orf19.810 864311 868181 2 864311|864430 864368|868181 864311 868115 orf19.8430|IPF26490.1|IPF5050.2|Contig4-2861_0001|orf6.6701|CA4212|CaO19.810|HFM1|CaO19.8430 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGDmod orf_changed=false scenario_first_exon=Z scenario_last_exon=D] Ca21chr2 866822 867576 - ntar_361 866822 867576 1 867576 866822 867031 866822 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 868073 869681 - orf19.809 868073 869681 1 869681 868073 869597 868233 orf19.8429|IPF26424.1|IPF5051.2|Contig4-2266_0004|orf6.6700|CA4211|CaO19.809|NOP12|CaO19.8429|IPF5052 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 870374 872769 + orf19.808 870374 872769 1 870374 872769 870747 872579 orf19.8428|IPF18239.1|IPF5056.3|Contig4-2266_0001|Contig4-2544_0011|orf6.2543|orf6.6699|orf6.6698|CA4209|DEP1|CaO19.808|CA4210|DEP1.5f|IPF18238.1|DEP1.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 872991 874901 + orf19.807 872991 874901 1 872991 874901 873052 874740 CHS5 orf19.8426|IPF19407.2|IPF5058.1|Contig4-2544_0010|orf6.173|orf6.2544|CA1176|CaO19.807|CA4208|CHS5.5eoc|IPF18240.1 Putative chitin biosynthesis protein; fungal-specific (no human or murine homolog); transcription decreases upon yeast-to-hyphal switch [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 874743 875462 - orf19.806 874743 875462 1 875462 874743 875340 874972 VMA7 orf19.8424|IPF5059.3|IPF5061.1|Contig4-2544_0008|orf6.175|orf6.2545|CA1177|CaO19.806 Putative subunit of the V-ATPase complex, which is involved in control of vacuolar pH; highly similar to S. cerevisiae Vma7p; interacts with phosphatidylinositol 3-kinase Vps34p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr2 875595 876659 + orf19.805 875595 876659 1 875595 876659 875646 876503 orf19.8423|IPF26444.1|IPF5062.1|Contig4-2544_0007|orf6.2546|CA1178|CaO19.805|IPF5062 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 876388 877043 - orf19.804.1 876388 877043 1 877043 876388 876989 876759 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 877165 878339 - orf19.804 877165 878339 1 878339 877165 878202 877222 orf19.8422|IPF26439.1|IPF5064.2|Contig4-2544_0004|orf6.2547|CA1179|CaO19.804|CaO19.8422|IPF5064 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 878586 880131 - orf19.802 878586 880131 1 880131 878586 880090 878675 UGA1 orf19.8421|IPF5067.2|IPF19652.1|IPF19651.1|Contig4-2544_0002|orf6.1355|orf6.2549|orf6.2548|CA1181|CA1180|orf19.803|UGA12.5f Protein described as GABA transaminase; transcription regulated by Mig1p and Tup1p; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 880839 883648 + orf19.801 880839 883648 1 880839 883648 880878 883538 TBF1 orf19.8420|IPF5070.2|IPF19724.1|Contig4-2905_0023|orf6.1354|orf6.2550|CA1182|CaO19.801|IPF19724 Essential transcriptional activator that binds to a conserved sequence at ribosomal protein genes and the rDNA locus; acts with Cbf1p at a subset of promoters; biological role is analogous to that of S. cerevisiae Rap1p, not to S.c. Tbf1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 883898 884149 - ntar_362 883898 884149 1 884149 883898 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 883980 884163 + ntar_363 883980 884163 1 883980 884163 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 884311 886207 + orf19.799 884311 886207 1 884311 886207 884534 885907 STE4 orf19.8419|IPF19618.2|IPF29653.1|Contig4-2905_0020|orf6.1139|orf6.1353|CA0438|CaO19.799|STE4.5eoc|IPF19618.1 Beta subunit of heterotrimeric G protein of mating signal transduction pathway; required for mating; transcription is specific to cells homozygous at MTL and is induced by alpha pheromone; similar to S. cerevisiae Ste4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 884493 885497 - ntar_364 884493 885497 1 885497 884493 885254 885129 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 885604 885901 - ntar_365 885604 885901 1 885901 885604 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 886008 887690 - orf19.798 886008 887690 2 887690|886962 887081|886008 887089 886180 TAF14 orf19.8418|IPF26447.1|IPF5074.1|Contig4-2905_0019|orf6.1138|CA0331|ANC1|CaO19.8418|CaO19.798 Putative DNA-binding transcription factor; putative TFIIF subunit; macrophage-induced protein [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 887743 889227 + orf19.797 887743 889227 1 887743 889227 887895 889076 BAT21 orf19.8417|IPF19656.1|IPF5075.1|Contig4-2905_0017|orf6.1137|orf6.2997|orf6.2998|CA0330|CaO19.797|BAT2 Protein described as a branched chain amino acid aminotransferase; regulated by Gcn4p, Gcn2p; induced in response to amino acid starvation (3-aminotriazole treatment) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 889067 890538 - orf19.796 889067 890538 1 890538 889067 890223 889210 HYM1 orf19.8415|IPF17942.2|IPF5076.1|Contig4-2905_0016|orf6.1136|orf6.2996|CA1470|CaO19.796|IPF17942 Mo25 family domain protein of RAM cell wall integrity signaling network; role in cell separation, azole sensitivity; required for hyphal growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 890713 892905 + orf19.795 890713 892905 1 890713 892905 890821 892818 VPS36 orf19.8414|IPF5078.2|IPF19036.2|Contig4-2905_0015|orf6.1135|orf6.2995|CA1469|CaO19.795|IPF5078 Protein involved in proteolytic activation of Rim101p, which regulates pH response; role in uptake of Histatin-5 into vacuole; similar to S. cerevisiae Vps36p, which is a member of the ESCRT II protein sorting complex [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 893084 895089 + orf19.794 893084 895089 1 893084 895089 893154 894980 orf19.8413|IPF26407.1|IPF5080.2|Contig4-2905_0013|orf6.2994|CA1468|SSN3|CaO19.794|CaO19.8413|SRB10 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 895141 896455 + orf19.793 895141 896455 1 895141 896455 895179 896198 CAK1 orf19.8412|IPF5082.2|IPF29659.1|Contig4-2905_0010|orf6.2993|CA1467|CaO19.793|IPF5082 Monomeric CDK-activating kinase (CAK); functional homolog of S. cerevisiae Cak1p; phosphorylates cyclin-free human CDK2; lacks glycine loop motif; conserved lysine (K36) not required for activity [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 897756 900981 + orf19.792 897756 900981 2 897756|899561 898775|900981 897896 900774 orf19.8411|IPF19058.1|IPF13324.1|IPF29658.1|Contig4-2905_0005|orf6.2992|orf6.1072|CA1466|orf19.1594|CaO19.8411|CaO19.792|IPF13324 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=F] Ca21chr2 898887 899116 + ntar_366 898887 899116 1 898887 899116 898887 899081 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 899222 900774 + orf19.791 899222 900774 1 899222 900774 899545 900774 RIM11 orf19.8410|IPF13327.2|IPF26457.1|IPF18668.1|Contig4-2905_0001|orf6.2991|orf6.1071|CA1465|orf19.1593|CaO19.791|RIM111|CaO19.8410 Protein not essential for viability; similar to S. cerevisiae Rim11p, which is a protein kinase involved in meiosis and sporulation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 900819 901888 - orf19.1592 900819 901888 1 901888 900819 901795 901037 IPF13328.2|orf6.1070|CA0291|CaO19.1592|IPF13328 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 902528 903973 + orf19.1591 902528 903973 1 902528 903973 902615 903823 ERG10 IPF13331.2|POT14|orf6.1069|CA0290|CaO19.1591 Protein similar to acetyl-CoA acetyltransferase; role in ergosterol biosynthesis; soluble in hyphae; changes in protein abundance associated with azole resistance; fluconazole or ketoconazole induced; macrophage-downregulated protein [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 904030 905822 + orf19.1590 904030 905822 1 904030 905822 904041 905822 IPF13333.3|orf6.1068|CA0289|CaO19.1590|IPF13333|IPF13333.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 905790 907140 - orf19.4521 905790 907140 1 907140 905790 906971 905961 orf19.11996|IPF22746.1|IPF15523.2|Contig4-2054_0005|orf6.4990|CA2906|CaO19.4521|CaO19.11996|IPF15523 Predicted ORF in Assemblies 19, 20 and 21; hyphal-induced expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 907391 907882 + ntar_367 907391 907882 1 907391 907882 907760 907882 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 907588 908450 - orf19.4520 907588 908450 1 908450 907588 908353 907778 orf19.11995|IPF22752.1|IPF15525.1|Contig4-2054_0003|orf6.4991|CA2907|CaO19.11995|CaO19.4520|IPF15525 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 908670 911048 - orf19.4519 908670 911048 1 911048 908670 910930 908768 SUV3 orf19.11994|IPF22739.1|IPF15527.2|orf6.4992|CA2908|CaO19.4519|CaO19.11994 Protein required for chlamydospore formation, for embedded hyphal growth, and for wild-type respiratory growth; similar to S. cerevisiae Suv3p, which is an RNA helicase involved in mitochondrial RNA catabolism [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 911479 914528 + orf19.4518 911479 914528 1 911479 914528 911560 914463 orf19.11993|IPF11424|IPF22738.1|IPF11424.1|Contig4-2521_0003|Contig4-2521_0005|Contig4-2521_0006|orf6.4993|CA2909|CaO19.4518|CaO19.11993 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 914757 916193 + orf19.4517 914757 916193 1 914757 916193 914828 916060 orf19.11992|IPF22745.1|IPF11421.1|Contig4-2521_0007|orf6.4994|CA2910|CaO19.11992|CaO19.4517|IPF11421 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 916006 917736 - orf19.4516 916006 917736 1 917736 916006 917707 916163 orf19.11991|IPF11207.3|IPF11419.2|Contig4-2521_0008|orf6.391|orf6.4995|CA2911|MET7|CaO19.4516 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 917843 919597 + orf19.4515 917843 919597 1 917843 919597 918785 919528 orf19.11990|IPF11417.1|IPF11206.1|Contig4-2521_0010|orf6.392|orf6.4996|CA2912|CIS303|CaO19.4515|IPF11206 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 920182 922415 + orf19.4513 920182 922415 1 920182 922415 920896 922086 orf19.11988|IPF11204.3|IPF11205.2|Contig4-2894_0002|orf6.280|orf6.4998|CA2913|CaO19.4513|IPF11205 Protein not essential for viability; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 922591 924837 + orf19.4511 922591 924837 1 922591 924837 922654 924717 orf19.11987|IPF19361.2|IPF11201.1|Contig4-2894_0006|Contig4-2894_0007|orf6.281|orf6.5000|orf6.4999|CA2915|CA2914|orf19.4512|IFA17.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 925655 927688 + orf19.4510 925655 927688 1 925655 927688 925655 927688 IFA4 orf19.11986|IPF22740.1|IPF11199.2|Contig4-2894_0009|orf6.5001|CA2916|CaO19.11986|LPF29|CaO19.4510 Predicted ORF in Assemblies 19, 20 and 21; oxidative stress-induced via Cap1p [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr2 928713 929033 + orf19.4509 928713 929033 1 928713 929033 928713 929033 orf19.11985|IPF22762.1|IPF16177.2|Contig4-2894_0010|orf6.5002|CA2917|LPF28|CaO19.11985|CaO19.4509|IFA18.5f|IPF16173.5f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 929054 929727 + orf19.4508 929054 929727 1 929054 929727 929080 929727 orf19.11984|IPF22750.1|IPF16174.2|Contig4-2894_0011|orf6.5003|CA2918|CaO19.4508|LPF27|CaO19.11984|IFA18.53f|IPF16173.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 929933 930837 + orf19.4507 929933 930837 1 929933 930837 930016 930831 orf19.11983|IPF22749.1|IPF16173.2|Contig4-2894_0012|orf6.5004|CA2919|LPF26|CaO19.11983|CaO19.4507|IFA18.3f|IFA18.3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 930829 931582 - ntar_368 930829 931582 1 931582 930829 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 932015 933487 + orf19.4506 932015 933487 1 932015 933487 932070 933323 LYS22 orf19.11982|IPF18482.1|IPF15851.2|Contig4-2894_0013|orf6.4198|orf6.5005|CA2335|CaO19.4506|LYS211|LYS21 Putative homocitrate synthase; fungal-specific (no human or murine homolog); repressed by nitric oxide; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 935072 935335 - ntar_369 935072 935335 1 935335 935072 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 935362 936551 + orf19.4505 935362 936551 1 935362 936551 935624 936472 ADH3 orf19.11981|IPF4795.1|IPF28369.1|Contig4-2894_0019|Contig4-2894_0020|CA2334|SAD3|CaO19.4505|ADH3.3f|orf6.4197 Expression is regulated upon white-opaque switching; induced by nitric oxide in yhb1 mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 935652 936425 - ntar_370 935652 936425 1 936425 935652 936130 935993 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 937472 938664 + orf19.4504 937472 938664 1 937472 938664 937567 938616 orf19.11980|IPF4794.1|IPF28368.1|orf6.4196|CA2333|SAD2|CaO19.4504|ADH4 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 937811 938274 - ntar_371 937811 938274 1 938274 937811 938274 938116 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 938793 939613 + orf19.4503 938793 939613 1 938793 939613 938829 939506 orf19.11979|IPF4792.1|IPF28370.1|Contig4-2993_0022|orf6.4195|CA2332|CaO19.4503|IPF4792 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 940531 946556 + orf19.4502 940531 946556 1 940531 946556 940777 946524 orf19.11978|IPF22754.1|IPF4789.2|Contig4-2993_0016|orf6.4194|CA2331|CaO19.4502|MOT1|CaO19.11978 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 946848 948355 + orf19.4499 946848 948355 1 946848 948355 947031 948230 RIM2 orf19.11975|IPF22747.1|IPF4785.2|Contig4-2993_0015|orf6.4191|CA2330|CaO19.11975|CaO19.4499 Protein similar to S. cerevisiae Rim2p; induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 947493 949240 - orf19.4498 947493 949240 1 949240 947493 949182 948475 orf19.11974|IPF22751.1|IPF4784.1|Contig4-2993_0012|orf6.4190|CA2329|CaO19.11974|CaO19.4498|IPF4784 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 949254 950345 + orf19.4497 949254 950345 1 949254 950345 949405 950124 MED8 orf19.11973|IPF4783.2|IPF19476.2|Contig4-2993_0011|orf6.30|orf6.4189|CA2328|CaO19.4497 Protein not essential for viability; similar to S. cerevisiae Med8p, which is a subunit of the RNA polymerase II mediator complex [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 950178 951592 - orf19.4496 950178 951592 1 951592 950178 951458 950406 orf19.11972|IPF4782.2|IPF19475.2|Contig4-2993_0010|orf6.31|orf6.4188|CA2327|CaO19.4496|IPF4782 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 951966 952273 + ntar_372 951966 952273 1 951966 952273 952141 952272 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 952333 954234 - orf19.4495 952333 954234 1 954234 952333 954019 952547 NDH51 orf19.11971|IPF4781.1|IPF4779.3|Contig4-2993_0009|orf6.2956|orf6.4187|CA2326|NUBM|CaO19.11971|CaO19.4495 Subunit of nicotinamide adenine dinucleotide dehydrogenase complex I, of the mitochondrial electron transport chain; required for wild-type filamentous growth; alkaline downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 954526 954832 + ntar_373 954526 954832 1 954526 954832 954526 954648 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 955166 956677 + orf19.4494 955166 956677 1 955166 956677 955166 956605 KTR2 orf19.11970|MNT5|IPF18483.2|IPF4778.2|Contig4-2993_0007|orf6.2955|orf6.4186|CA1444|CaO19.4494 Protein with similarity to S. cerevisiae Ktr2p, which is a mannosyltransferase; transcription is elevated in chk1, nik1, and sln1 homozygous null mutants; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr2 956622 956915 - ntar_374 956622 956915 1 956915 956622 956915 956739 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 956890 958288 + orf19.4492 956890 958288 1 956890 958288 956939 958219 orf19.11968|IPF22744.1|IPF4776.2|Contig4-2993_0006|orf6.2953|CA1443|CaO19.4492|EBP2|CaO19.11968|IPF4776 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 958643 959809 + orf19.4491 958643 959809 1 958643 959809 958692 959747 ERG20 orf19.11967|IPF22748.1|IPF4775.2|Contig4-2993_0004|orf6.2952|CA1442|CaO19.11967|CaO19.4491 Putative farnesyl pyrophosphate synthetase involved in isoprenoid and sterol biosynthesis, based on similarity to S. cerevisiae Erg20p; likely to be essential for growth, based on an insertional mutagenesis strategy [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 959725 960294 - orf19.4490.2 959725 960294 1 960294 959725 960251 959964 QCR8 IPF22763.1|IPF4774.1|Contig4-2993_0003|CA1441 ORF Predicted by Annotation Working Group; shows colony morphology-related gene regulation by Ssn6p; macrophage/pseudohyphal-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 960915 962041 - orf19.4490 960915 962041 1 962041 960915 961997 961440 RPL17B orf19.11966|IPF22753.1|IPF4772.1|Contig4-2993_0002|orf6.2951|CA1440|CaO19.4490|RPL17|CaO19.11966 Predicted ribosomal protein; mutation confers hypersensitivity to 5-FU, tubercidin (7-deazaadenosine); genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated on phagocytosis by macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 962514 964627 + ntar_1417 962514 964627 2 962514|963437 963320|964627 [label_first_exon=CGDmod label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 963232 964529 - ntar_1418 963232 964529 2 964529|964439 964507|963232 964208 963927 [label_first_exon=CGD label_last_exon=CGD orf_changed=true scenario_first_exon=Z scenario_last_exon=C] Ca21chr2 964910 968536 + orf19.4488 964910 968536 1 964910 968536 965502 968417 orf19.11964|IPF19603.2|IPF19602.1|Contig4-2699_0008|orf6.2949|orf6.751|CA1439|SWI3|CaO19.4488|IPF19602 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 968379 969291 - ntar_375 968379 969291 1 969291 968379 968603 968379 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 969575 969741 - ntar_376 969575 969741 1 969741 969575 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 969586 970436 + ntar_377 969586 970436 1 969586 970436 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 970688 971016 + ntar_378 970688 971016 1 970688 971016 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 971259 971725 + ntar_379 971259 971725 1 971259 971725 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 971654 974945 - orf19.144 971654 974945 1 974945 971654 974872 971804 SNU114 orf19.7784|IPF16740.2|IPF29942.1|Contig4-2900_0027|orf6.1176|CA0350|CaO19.144 Protein likely to be essential for growth, based on an insertional mutagenesis strategy; similar to S. cerevisiae Snu114p, which is an RNA helicase involved in pre-mRNA splicing [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 975173 976564 - orf19.145 975173 976564 1 976564 975173 976175 975366 RPB4 orf19.7785|orf19.7786|IPF27151.1|IPF27153.1|IPF19620.1|IPF19621.1|orf6.1177|orf6.1178|CA0351|CA0352|orf19.146|RPB4.3f Protein similar to S. cerevisiae Rpb4p, which is a component of RNA polymerase II; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 976693 979745 - orf19.147 976693 979745 1 979745 976693 979332 976903 YAK1 orf19.7787|orf19.7788|IPF27150.1|IPF16042.2|IPF16043.2|IPF19456.2|orf6.1179|orf6.63|orf6.1180|CA0353|CA0354|orf19.148|YAK1.3f Predicted serine-threonine protein kinase involved in hyphal growth regulation and biofilm formation; induced in core caspofungin response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 980006 980443 + orf19.149 980006 980443 1 980006 980443 980006 980443 IPF27154.1|IPF29941.1|orf6.62 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 981103 982080 + orf19.150 981103 982080 1 981103 982080 981178 981642 orf19.7790|IPF16036.1|IPF29940.1|Contig4-1742_0002|orf6.75|CA0010|CaO19.150|TIM17|CaO19.7790|IPF16036 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 982171 984780 - orf19.151 982171 984780 1 984780 982171 984458 982446 TPO5 orf19.7792|IPF19097.2|IPF17861.2|IPF19195.1|orf6.662|orf6.76|orf6.660|CA0144|CA0143|orf19.153|CaO19.151|IPF19195.3f Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to toxic ergosterol analog; hyphal induced; macrophage induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 984861 986133 - orf19.154 984861 986133 1 986133 984861 986084 984999 orf19.7793|IPF19598.1|IPF19599.1|orf6.659|orf6.940|CA0234|UTP30|CaO19.154|IFA3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 986320 987984 - orf19.155 986320 987984 1 987984 986320 987521 986487 URE2 orf19.7794|IPF15126.2|IPF19196.2|orf6.658|orf6.939|CA0233|CaO19.155 Functional homolog of S. cerevisiae Ure2p, which is a regulator of nitrogen utilization, and which also has a prion form called [URE3] [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 988114 988471 + ntar_380 988114 988471 1 988114 988471 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 988361 991024 - orf19.156 988361 991024 1 991024 988361 990196 988715 FGR51 orf19.7795|orf19.7796|orf19.7825|IPF27149.1|IPF15128.2|IPF27152.1|IPF15129.1|IPF16389.1|IPF19828.2|Contig4-1770_0004|orf6.938|orf6.937|orf6.1144|orf6.196|CA0232|CA6168|CA0335|orf19.157|orf19.195|LPF3|CaO19.7795|CaO19.156|IFA1 Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 991626 993398 + orf19.194 991626 993398 1 991626 993398 991714 993321 orf19.7824|IPF19562.1|IPF19563.2|Contig4-2639_0010|orf6.1143|orf6.197|CA0334|CaO19.194|IPF19562 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 993340 994444 - orf19.193 993340 994444 1 994444 993340 994229 993393 orf19.7823|IPF27135.1|IPF14730.2|Contig4-2639_0009|orf6.2966|orf6.1142|CA1449|CaO19.193|IPF14730|IPF14730.5eoc|IPF14730.1 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 995232 997258 + orf19.192 995232 997258 1 995232 997258 995424 997127 orf19.7822|IPF27132.1|IPF14728.2|Contig4-2639_0004|Contig4-2639_0005|orf6.2965|CA1448|CaO19.7822|CaO19.192|IPF14728 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 997629 1000646 + orf19.191 997629 1000646 1 997629 1000646 997849 1000524 KIC1 orf19.7821|IPF27130.1|IPF15055.2|Contig4-2639_0001|orf6.2964|CA1447|CaO19.191|CaO19.7821|NRK1 Member of the GCK-III subfamily of eukaryotic Ste20p kinases; in RAM cell wall integrity signaling network; role in cell separation, azole sensitivity; required for hyphal growth; constitutive expression is MTL, white-opaque independent [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1000689 1001822 + orf19.190 1000689 1001822 1 1000689 1001822 1000848 1001822 orf19.7820|IPF27134.1|IPF15052.3|orf6.2963|CA1446|CaO19.190|CaO19.7820|YAL011|IPF15052.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1001967 1004449 + orf19.188 1001967 1004449 1 1001967 1004449 1001967 1004417 orf19.7818|IPF13416.3|IPF18673.1|IPF13410.3|orf6.2960|orf6.950|orf6.2961|CA6314|CA0237|orf19.187|CaO19.188|IPF13416.5f|IPF13416|IPF13416.2 Predicted ORF in Assemblies 19, 20 and 21; merged with orf19.187 in Assembly 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1004375 1005680 - orf19.185 1004375 1005680 1 1005680 1004375 1005644 1004538 orf19.7816|IPF13418.1|IPF13417.3|Contig4-1757_0005|orf6.2958|orf6.948|CA1445|MRP51|CaO19.185|IPF13417.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1005838 1007406 - orf19.184 1005838 1007406 1 1007406 1005838 1007321 1005900 orf19.7814|IPF13419.2|IPF29930.1|Contig4-1757_0003|orf6.2957|orf6.946|CA0236|CaO19.184|MDM10 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1007680 1008438 + orf19.183 1007680 1008438 1 1007680 1008438 1007761 1008429 HIS3 orf19.7813|IPF13420.2|IPF19395.2|Contig4-2218_0007|orf6.945|CA0235|CaO19.183 Imidazoleglycerol-phosphate dehydratase, enzyme of histidine biosynthesis; functionally complements S. cerevisiae his3-1 mutation; hyphal-induced expression; regulated by Gcn2p and Gcn4p; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1008618 1010185 + orf19.182 1008618 1010185 1 1008618 1010185 1008679 1010094 orf19.7812|IPF27133.1|IPF27131.1|IPF13421.3|IPF19396.1|Contig4-2218_0006|orf6.195|orf6.944|CA0029|PET56|IPF13421.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1009709 1010578 - ntar_381 1009709 1010578 1 1010578 1009709 1010578 1010069 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1010469 1010617 - ntar_382 1010469 1010617 1 1010617 1010469 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1010664 1012129 + orf19.4128 1010664 1012129 1 1010664 1012129 1010792 1012096 orf19.7811|IPF27136.1|IPF19397.2|IPF13423.2|Contig4-1469_0001|Contig4-2218_0004|orf6.194|orf6.2517|CA1159|orf19.181|CaO19.4128|IPF13423 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1010748 1010993 - ntar_383 1010748 1010993 1 1010993 1010748 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1013075 1014768 - orf19.4127 1013075 1014768 2 1014768|1014442 1014521|1013075 1014567 1013161 IPF13275.2|Contig4-2218_0002|orf6.2516|CA1158|IPF13275 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1015883 1017193 + orf19.4125 1015883 1017193 1 1015883 1017193 1015910 1017148 IPF13278.2|Contig4-2828_0002|orf6.2514|CA1157|CaO19.4125|PZF1 Putative transcription factor with zinc finger DNA-binding motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1016993 1022071 - orf19.4123 1016993 1022071 1 1022071 1016993 1022071 1017245 IPF10133.2|Contig4-2828_0004|Contig4-2828_0005|Contig4-2828_0007|orf6.2512|CA1156|RLR1|CaO19.4123 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr2 1022368 1024005 - orf19.3521 1022368 1024005 1 1024005 1022368 1023958 1023164 ARH2 orf19.11004|IPF23741.1|IPF17908.2|orf6.2034 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1024084 1024155 - td(guc)5 1024084 1024155 1 1024155 1024084 tD(GUC)5.2 tRNA-Asp predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1024932 1025886 + ntar_384 1024932 1025886 1 1024932 1025886 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1026295 1026600 + orf19.3522 1026295 1026600 1 1026295 1026600 1026295 1026600 orf19.11005|IPF17272|IPF19533.2|IPF17272.2|Contig4-1527_0001|Contig4-2828_0015|orf6.2035|CA0860|CaO19.11005|CaO19.3522|IPF17272.3f Predicted ORF in Assemblies 19, 20 and 21; transcription is downregulated in response to treatment with ciclopirox olamine [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1026601 1027051 - ntar_385 1026601 1027051 1 1027051 1026601 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1027235 1027305 + tg(gcc)3 1027235 1027305 1 1027235 1027305 tG(GCC)3.2 tRNA-Gly predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1027412 1029803 - orf19.3523 1027412 1029803 1 1029803 1027412 1029687 1027450 CRK1 orf19.11006|IPF4453.2|IPF17271.2|Contig4-2828_0017|orf6.2036|orf6.2037|orf6.308|CA0861|CA0862|orf19.3524|CaO19.3523|CRK1.3f Protein kinase of the Cdc2 kinase subfamily involved in hyphal development and virulence; promotes hyphal development independently of Cph1 and Efg1; functionally complements pheromone hypersensitivity of S. cerevisiae sgv1 mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1029951 1031983 - orf19.3526 1029951 1031983 1 1031983 1029951 1031796 1030132 ITR1 orf19.11009|ITR2|IPF23713.1|IPF4456.1|Contig4-2828_0018|orf6.2039|orf6.310|CA0863|HGT15|CaO19.3526 Inositol transporter required for uptake of exogenous inositol; major facilitator superfamily; 12 probable transmembrane motifs; expressed in rich medium with 2% glucose; fluconazole, caspofungin downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1030300 1030555 + ntar_386 1030300 1030555 1 1030300 1030555 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1032381 1032661 + ntar_387 1032381 1032661 1 1032381 1032661 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1032672 1034089 - orf19.3527 1032672 1034089 1 1034089 1032672 1033784 1032918 CYT1 orf19.11011|orf6.1503|orf6.2040|IPF23744.1|IPF4458.2|Contig4-2446_0010|CA0864|CaO19.3527|CA0524|CYT12|IPF18952.1 Protein described as cytochrome c1; transcriptionally regulated by iron; expression greater in high iron; alkaline downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1034385 1035394 - orf19.3528 1034385 1035394 1 1035394 1034385 1035301 1034873 orf19.11012|IPF4459.2|IPF28737.1|Contig4-2446_0009|orf6.1502|orf6.2041|CA0523|CaO19.3528|IPF4459 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1035615 1035822 - ntar_388 1035615 1035822 1 1035822 1035615 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1036722 1038554 + orf19.3529 1036722 1038554 1 1036722 1038554 1036722 1038554 ABP2 orf19.11013|IPF4463.2|IPF28729.1|Contig4-2446_0007|orf6.1501|CA0522|CaO19.3529|CaO19.11013|IPF4463 Protein of unknown function; induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr2 1038560 1039990 - orf19.3530 1038560 1039990 1 1039990 1038560 1039733 1038744 CKA2 orf19.11014|IPF23734.1|IPF4465.2|Contig4-2446_0005|orf6.1500|CA0521|CaO19.3530|CaO19.11014 Catalytic subunit (alpha-subunit) of protein kinase CK2; interaction with calcineurin pathway to affect fluconazole sensitivity; not essential for viability; synthetically lethal with CKA1; similar to S. cerevisiae Cka2p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1040073 1041130 + orf19.3531 1040073 1041130 1 1040073 1041130 1040198 1041031 orf19.11015|IPF23736.1|IPF4466.2|Contig4-2446_0002|orf6.1499|CA0520|CaO19.3531|CaO19.11015|IPF4466 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1041018 1041983 - orf19.3532 1041018 1041983 1 1041983 1041018 1041938 1041087 MRPL10 orf19.11016|IPF19871.1|IPF4468.3|orf6.1498|CA0519|CaO19.3532|CaO19.11016|MRPL10.3 Predicted ORF in Assemblies 19, 20 and 21; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1042518 1042590 + tt(agu)4 1042518 1042590 1 1042518 1042590 tT(AGU)4.2 tRNA-Thr predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1042766 1043496 + orf19.3533 1042766 1043496 1 1042766 1043496 1043020 1043469 orf19.11017|IPF6421.2|IPF4470.2|Contig4-2990_0021|orf6.4279|orf6.607|CA0130|CaO19.3533|CaO19.11017|IPF4470 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1043449 1044542 - orf19.3534 1043449 1044542 2 1044542|1044184 1044276|1043449 1044306 1043583 RHO3 orf19.11018|IPF6422.1|IPF4472.1|Contig4-2990_0019|orf6.4280|orf6.606|CA2393 Putative Rho family GTPase; possible substrate of protein farnesyltransferase and geranylgeranyltransferase type I; greater transcription in hyphal form than yeast form [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1044693 1045757 - orf19.3535 1044693 1045757 1 1045757 1044693 1045705 1044839 orf19.11019|IPF6424.1|IPF4474.2|Contig4-2990_0017|orf6.4281|orf6.605|CA2394|CaO19.3535|IPF6424 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1045862 1047425 - orf19.3536 1045862 1047425 1 1047425 1045862 1047388 1046000 orf19.11020|IPF23723.1|IPF6425.1|Contig4-2990_0016|orf6.4282|CA2395|CaO19.3536|CaO19.11020|IPF6425 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1047769 1048421 - orf19.3537 1047769 1048421 1 1048421 1047769 1048327 1047929 orf19.11021|IPF23756.1|IPF6428.1|Contig4-2990_0015|orf6.4283|CA2396|CaO19.3537|CaO19.11021|IPF6428 Predicted ORF in Assemblies 19, 20 and 21; regulated by Tsa1p, Tsa1Bp in minimal media at 37 deg [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1049271 1051538 + orf19.3538 1049271 1051538 1 1049271 1051538 1049271 1051520 FRE9 orf19.11022|CFL12|IPF23706.1|IPF6430.2|CFL98|Contig4-2990_0013|orf6.4284|CA2397|CaO19.3538|CFL8|CaO19.11022 Protein similar to ferric reductase Fre10p; alkaline upregulated; ciclopirox olamine induced; induced by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr2 1051534 1052887 - orf19.3539 1051534 1052887 1 1052887 1051534 1052802 1051816 orf19.11023|IPF23732.1|IPF6431.2|Contig4-2990_0011|orf6.4285|CA2398|CaO19.11023|CaO19.3539|IPF6431 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1052953 1055550 + orf19.3540 1052953 1055550 1 1052953 1055550 1053006 1055354 MAK5 orf19.11024|IPF23705.1|IPF6433.2|Contig4-2990_0009|orf6.4286|CA2399|CaO19.3540|CaO19.11024 Predicted ORF in Assemblies 19, 20 and 21; oxidative stress-repressed via Cap1p; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1055351 1056866 - orf19.3541 1055351 1056866 1 1056866 1055351 1056790 1055480 ERF1 orf19.11025|IPF23726.1|IPF6434.1|Contig4-2990_0007|orf6.4287|CA2400|SUP45|CaO19.11025|CaO19.3541 Putative translation release factor 1, which interacts with stop codons and promotes release of nascent peptides from ribosomes [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1057042 1058820 + orf19.3542 1057042 1058820 1 1057042 1058820 1057098 1058417 LEM3 orf19.11026|IPF23722.1|IPF6435.1|Contig4-2990_0004|orf6.4288|CA2401|CaO19.3542|CaO19.11026 Predicted ORF in Assemblies 19, 20 and 21; mutation causes increased resistance to miltefosine [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1058455 1058799 - orf19.3543 1058455 1058799 1 1058799 1058455 1058799 1058455 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1058923 1060101 - ntar_389 1058923 1060101 1 1060101 1058923 1059931 1059761 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1058999 1060174 + orf19.3544 1058999 1060174 1 1058999 1060174 1059033 1060151 orf19.11028|IPF23729.1|IPF6438.1|Contig4-2990_0001|orf6.4290|CA2403|CaO19.3544|CaO19.11028|IPF6438 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1060351 1063844 + orf19.3545 1060351 1063844 1 1060351 1063844 1060401 1063781 orf19.11029|IPF6439.3|IPF28743.1|Contig4-2204_0004|orf6.4291|orf6.4656|CA2404|CDC15|CaO19.3545|SEP|CA2669|IPF17494.3eoc|IPF17494.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1063940 1065347 + orf19.3546 1063940 1065347 1 1063940 1065347 1064025 1065287 orf19.11030|IPF23725.1|IPF17553.2|Contig4-2204_0003|orf6.4655|CA2668|PEX2|CaO19.3546|CaO19.11030|IPF17553 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1065269 1067343 - orf19.3547 1065269 1067343 1 1067343 1065269 1067309 1065306 orf19.11031|IPF23709.1|IPF16996.2|Contig4-2204_0001|orf6.4654|CA2667|CaO19.11031|CaO19.3547|IPF16996 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1067501 1068433 + orf19.3548 1067501 1068433 1 1067501 1068433 1067541 1068212 orf19.11032|IPF23738.1|IPF16995.2|orf6.4653|CA2666|CaO19.3548|CaO19.11032|IPF16995 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1068915 1069409 + orf19.3548.1 1068915 1069409 1 1068915 1069409 1069064 1069261 WH11 IPF23703.1|IPF13362.2|Contig4-1753_0002 Cytoplasmic protein expressed specifically in white phase yeast-form cells; expression in opaque cells increases virulence and frequency of opaque-to-white switching; null mutant shows wild-type switching; similar to S. cerevisiae Hsp12p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1069604 1070636 + orf19.3549 1069604 1070636 1 1069604 1070636 1069634 1070581 CDC21 orf19.11033|TMP1|IPF19442.2|IPF13364.2|Contig4-1753_0001|orf6.102|orf6.4652|CA2665|CaO19.3549|CaO19.11033 Predicted ORF in Assemblies 19, 20 and 21; flucytosine induced; transcription is downregulated in both intermediate and mature biofilms [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1070565 1072113 - orf19.3550 1070565 1072113 1 1072113 1070565 1072037 1070682 SGO1 orf19.11034|IPF13368.3|IPF28734.1|Contig4-1753_0003|orf6.103|orf6.4651|CA0014|CaO19.3550|IPF13368|IPF13368.2 Predicted ORF in Assemblies 19, 20 and 21; cell-cycle regulated periodic mRNA expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1072209 1073071 + orf19.3551 1072209 1073071 1 1072209 1073071 1072240 1072617 IPF13367.3|IPF13370.2|orf6.4650|CA2664|CaO19.3551|IPF13370 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1072526 1075874 - orf19.3552 1072526 1075874 1 1075874 1072526 1075769 1072671 orf19.11035|IPF23764.1|IPF13373.2|Contig4-1650_0003|orf6.4649|CA2663|NUP133|CaO19.3552|CaO19.11035 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1076045 1077201 - orf19.3553 1076045 1077201 1 1077201 1076045 1077167 1076184 RPF2 orf19.11036|IPF23733.1|IPF17139.2|Contig4-1650_0001|orf6.4648|CA2662|CaO19.3553|CaO19.11036|IPF17139 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1077471 1077556 - tq(uug)3 1077471 1077556 2 1077556|1077505 1077519|1077471 tQ(UUG)3.2 tRNA-Gln predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1077636 1079228 - orf19.3554 1077636 1079228 1 1079228 1077636 1079143 1077830 AAT1 orf19.11037|IPF18970.2|IPF14258.2|Contig4-2239_0001|Contig4-2239_0002|orf6.1447|orf6.4647|CA2661|CaO19.3554 Protein described as aspartate aminotransferase; soluble protein in hyphae; macrophage-induced protein; alkaline upregulated; amphotericin B repressed; gene used for strain identification by multilocus sequence typing, farnesol-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1080136 1080374 + ntar_390 1080136 1080374 1 1080136 1080374 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1082482 1082678 + ntar_391 1082482 1082678 1 1082482 1082678 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1083510 1086320 + orf19.3555 1083510 1086320 1 1083510 1086320 1083888 1086293 orf19.11038|IPF17574.2|IPF16659.3|Contig4-2581_0007|orf6.1448|orf6.4646|orf6.837|CA0485|CaO19.3555|IPF17574 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1086588 1089848 + orf19.3556 1086588 1089848 1 1086588 1089848 1086748 1089594 orf19.11040|IPF23708.1|IPF16463.2|Contig4-1675_0003|orf6.1449|orf6.836|CA0199|CaO19.3556|KAP104 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1089710 1090805 - orf19.3557 1089710 1090805 1 1090805 1089710 1090805 1089909 orf19.11041|IPF3180.2|IPF19128.2|Contig4-1675_0002|orf6.1605|orf6.835|CA0582|CaO19.3557|IPF3180 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1090856 1091631 - orf19.3558 1090856 1091631 1 1091631 1090856 1091497 1090856 orf19.11042|IPF23742.1|IPF3181.2|Contig4-1675_0001|orf6.1604|CA0581|CaO19.3558|ERP3|CaO19.11042|IPF3181 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1091779 1093149 - orf19.3559 1091779 1093149 2 1093149|1092328 1092611|1091779 1093099 1091873 orf19.11043|orf19.11044|IPF23746.1|IPF23749.1|IPF3184.1|IPF3182.1|Contig4-2222_0002|Contig4-2222_0003|orf6.1603|orf6.1602|CA0579|orf19.3560|IPF3184|CA0580|IPF3184.exon2|IPF3184.exon1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1093450 1095656 + orf19.3561 1093450 1095656 1 1093450 1095656 1093604 1095574 CDC7 orf19.11045|IPF19636.2|IPF19635.2|Contig4-3023_0026|orf6.1601|orf6.5768|CA3493|CaO19.3561|IPF19635.1 Predicted ORF in Assemblies 19, 20 and 21; cell-cycle regulated periodic mRNA expression; S. cerevisiae ortholog is not cell-cycle regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1095678 1097421 - orf19.3563 1095678 1097421 1 1097421 1095678 1097408 1095735 orf19.11047|IPF3189|IPF23714.1|IPF3189.1|Contig4-3023_0025|orf6.5766|CA3492|CaO19.3563|CaO19.11047 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1097782 1099094 - orf19.3564 1097782 1099094 1 1099094 1097782 1099029 1098019 RPC40 orf19.11048|IPF23728.1|IPF3191.1|Contig4-3023_0023|orf6.5765|CA3491|CaO19.11048|CaO19.3564 Predicted ORF in Assemblies 19, 20 and 21; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1099295 1100468 - orf19.3565 1099295 1100468 1 1100468 1099295 1100407 1099547 orf19.11049|IPF23737.1|IPF3192.1|Contig4-3023_0022|orf6.5764|CA3490|CaO19.11049|CaO19.3565|IPF3192 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1100622 1102160 - orf19.3567 1100622 1102160 1 1102160 1100622 1102082 1100622 BIO32 orf19.11051|IPF23721.1|IPF3195.1|Contig4-3023_0021|orf6.5762|CA3489|CaO19.3567|CaO19.11051|IPF3195 Predicted ORF in Assemblies 19, 20 and 21; induced during planktonic growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chr2 1102442 1104530 - orf19.3568 1102442 1104530 1 1104530 1102442 1104197 1102641 RXT3 orf19.11052|IPF23717.1|IPF3198.2|Contig4-3023_0020|orf6.5761|CA3488|CaO19.11052|CaO19.3568|IPF3198 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1106030 1108121 + orf19.3569 1106030 1108121 1 1106030 1108121 1106693 1107811 orf19.11053|IPF23730.1|IPF3203.2|Contig4-3023_0017|orf6.5760|CA3487|YLR407w|CaO19.11053|CaO19.3569|IPF3203 Predicted ORF in Assemblies 19, 20 and 21; constitutive expression independent of MTL or white-opaque status [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1107795 1108520 - orf19.3571 1107795 1108520 1 1108520 1107795 1108503 1108087 orf19.11055|IPF23754.1|IPF3204.1|Contig4-3023_0016|orf6.5758|CaO19.3571|CaO19.11055 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1108672 1110051 + orf19.3572 1108672 1110051 1 1108672 1110051 1108751 1110046 orf19.11056|IPF23727.1|IPF3206.1|Contig4-3023_0015|orf6.5757|CA3486|CaO19.3572|CaO19.11056|IPF3206 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 1109027 1109219 - ntar_392 1109027 1109219 1 1109219 1109027 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1109635 1110052 - ntar_393 1109635 1110052 1 1110052 1109635 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1110395 1111749 + orf19.3572.3 1110395 1111749 2 1110395|1111064 1110581|1111749 1110528 1111348 IPF23702.1|IPF3208.1|Contig4-3023_0009 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1111558 1112050 - ntar_1427 1111558 1112050 2 1112050|1111686 1111986|1111558 [label_first_exon=CGD label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1112294 1112380 - ti(aau)3 1112294 1112380 2 1112380|1112329 1112343|1112294 tI(AAU)3.2 tRNA-Ile predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1112810 1116477 + orf19.3573 1112810 1116477 1 1112810 1116477 1112926 1116399 orf19.11057|IPF23761.1|IPF3213.2|Contig4-3023_0005|Contig4-3023_0006|orf6.5756|CA3485|PEX6|CaO19.3573|CaO19.11057|IPF3213 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1116468 1117283 - orf19.3574 1116468 1117283 1 1117283 1116468 1117170 1116739 orf19.11058|IPF23751.1|IPF3214.1|Contig4-3023_0004|orf6.5755|CA3484|MDJ2|CaO19.11058|CaO19.3574|IPF3214 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1117517 1118289 - ntar_394 1117517 1118289 1 1118289 1117517 1118267 1118136 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1118680 1120407 + orf19.3575 1118680 1120407 1 1118680 1120407 1118746 1120260 CDC19 orf19.11059|PYK1|IPF23718.1|IPF19988.1|Contig4-3023_0002|Contig4-3023_0003|orf6.5754|CA3483|CaO19.3575|CaO19.11059 Putative pyruvate kinase; on yeast-form cell surface; soluble in hyphae; antigenic; Gcn4p, Hog1p regulated; induced on polystyrene adherence; downregulated upon phagocytosis, farnesol treatment; mutation affects filamentation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1120580 1121656 + orf19.3577 1120580 1121656 1 1120580 1121656 1120618 1121538 COQ5 orf19.11061|IPF23735.1|IPF3222.1|Contig4-3023_0001|orf6.5752|CA3482|CaO19.3577|CaO19.11061 Protein described as methyltransferase of ubiquinone biosynthesis; regulated by Gcn4p; repressed in response to amino acid starvation (3-aminotriazole treatment); induced upon adherence to polystyrene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1121577 1122064 - orf19.3577.1 1121577 1122064 1 1122064 1121577 1121940 1121686 IPF23701.1|IPF3223.1|CA3481|IPF3223 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1122025 1122610 + orf19.3578 1122025 1122610 1 1122025 1122610 1122114 1122560 orf19.11062|IPF23750.1|IPF3224.1|orf6.5751|CA3480|CaO19.11062|CaO19.3578|IPF3224 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1122750 1123596 + orf19.3579 1122750 1123596 1 1122750 1123596 1122782 1123483 ATP4 orf19.11063|IPF23739.1|IPF3225.1|Contig4-2234_0001|orf6.5750|CA3479|CaO19.11063|CaO19.3579 Predicted ORF in Assemblies 19, 20 and 21; macrophage/pseudohyphal-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1123496 1124943 - orf19.3581 1123496 1124943 1 1124943 1123496 1124918 1123611 orf19.11065|IPF23724.1|IPF3227.1|Contig4-2234_0002|orf6.5748|CA3478|CaO19.3581|MSI1|CaO19.11065|IPF3227 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1125255 1126257 + orf19.3582 1125255 1126257 2 1125255|1125448 1125388|1126257 1125339 1126138 orf19.11066|IPF23740.1|IPF3229.1|Contig4-2234_0003|orf6.5747|CA3477|CaO19.11066|CaO19.3582|IPF3229 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1125897 1127444 - orf19.3583 1125897 1127444 1 1127444 1125897 1127371 1126214 orf19.11067|IPF23731.1|IPF3232.2|orf6.5746|CA3476|CaO19.3583|YRB2|CaO19.11067|YRB2.3eoc|NUP2.3eoc Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1127551 1128872 - orf19.6866 1127551 1128872 2 1128872|1128713 1128790|1127551 1128792 1127673 orf19.14156|IPF8044|IPF20238.1|IPF8044.2|Contig4-3086_0001|orf6.7130|CA4556|U1-70K Putative U1-70K component of the U1 snRNP, involved in splicing; ortholog of S. cerevisiae SNP1; downregulated upon adherence to polystyrene; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1128951 1129715 + orf19.6867 1128951 1129715 1 1128951 1129715 1129080 1129469 IPF20253.1|IPF8043.1|Contig4-3086_0003|orf6.7131|CA4557|CaO19.6867|IPF8043 Predicted ORF in Assemblies 19, 20 and 21; transcription is repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1129761 1130943 + orf19.6868 1129761 1130943 1 1129761 1130943 1129825 1130841 orf19.14157|IPF20237.1|IPF8042.1|Contig4-3086_0005|orf6.7132|CA4558|CaO19.14157|GRE24|CaO19.6868|GRP5 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1130851 1132231 - orf19.6869 1130851 1132231 1 1132231 1130851 1132002 1130953 orf19.14158|IPF20236.1|IPF8041.1|Contig4-3086_0006|orf6.7133|CA4559|CaO19.6869|BZD98|CaO19.14158|IPF8041 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1134927 1139253 + orf19.6871 1134927 1139253 1 1134927 1139253 1135090 1139148 orf19.14160|IPF20248.1|IPF8038.2|Contig4-3086_0013|orf6.7135|CA4560|CaO19.14160|CaO19.6871|IPF8038 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1139235 1140512 - orf19.6872 1139235 1140512 1 1140512 1139235 1140248 1139328 orf19.14161|IPF20239.1|IPF8031.2|Contig4-3086_0014|orf6.7136|CA4561|CaO19.6872|CaO19.14161|IPF8031 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1141109 1141513 + ntar_395 1141109 1141513 1 1141109 1141513 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1141564 1142796 - orf19.6873 1141564 1142796 2 1142796|1142399 1142765|1141564 1142393 1141773 RPS8A orf19.14162|IPF20242.1|IPF6565.2|Contig4-3086_0015|orf6.7137|CA4562|RPS8|CaO19.6873|CaO19.14162 Putative ribosomal protein; similar to S. cerevisiae Rps8Bp; gene is induced by ciclopirox olamine treatment; genes encoding cytoplasmic ribosomal subunits are downregulated upon phagocytosis by murine macrophage; intron in 5'-UTR [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1143198 1143882 + orf19.6873.1 1143198 1143882 1 1143198 1143882 1143299 1143511 IPF20221.1|IPF6566.1|Contig4-3086_0017|CA4563|IPF6566 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1143939 1144020 - ts(aga)4 1143939 1144020 1 1144020 1143939 tS(AGA)4.2 tRNA-Ser predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1149754 1152305 + orf19.6874 1149754 1152305 1 1149754 1152305 1150098 1151921 orf19.14163|IPF20227.1|IPF6572.2|Contig4-3086_0028|orf6.7138|CA4564|BAS1|CaO19.6874|CaO19.14163|IPF6572 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1152553 1155706 + orf19.6875 1152553 1155706 1 1152553 1155706 1152671 1155505 VPS35 orf19.14164|IPF20219.1|IPF6573.1|Contig4-3086_0031|orf6.7139|CA4565|CaO19.6875|CaO19.14164 Putative role in vacuolar sorting; downregulated in biofilm; induced upon adherence to polystyrene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1155977 1156267 - ntar_396 1155977 1156267 1 1156267 1155977 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1156829 1160245 + orf19.6877 1156829 1160245 1 1156829 1160245 1157113 1160064 PNG2|orf19.14166|IPF20218.1|IPF19801.1|Contig4-3086_0035|orf6.7141|CA4566|CaO19.14166|CaO19.6877|IPF19801 Predicted ORF in Assemblies 19, 20 and 21; transcription is upregulated in response to treatment with caspofungin, ciclopirox olamine or ketoconazole; gene of core caspofungin response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1160117 1161118 - orf19.6879 1160117 1161118 1 1161118 1160117 1161071 1160271 orf19.14168|IPF20240.1|IPF9555.1|Contig4-3086_0036|orf6.7143|CA4567|CaO19.6879|SEN34|CaO19.14168|IPF9555 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1161271 1164212 + orf19.6880 1161271 1164212 1 1161271 1164212 1161404 1164073 orf19.14169|IPF20224.1|IPF9554.1|Contig4-3086_0037|orf6.7144|CA4568|COG4|CaO19.14169|CaO19.6880|IPF9554 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1164106 1164971 - orf19.6881 1164106 1164971 1 1164971 1164106 1164808 1164161 YTH1 orf19.14170|IPF20241.1|IPF9552.1|Contig4-3086_0038|orf6.7145|CA4569|CaO19.6881|CaO19.14170|IPF9552 Protein described as an mRNA cleavage and polyadenylation specificity factor; transcription is regulated upon yeast-hyphal switch; decreased expression in hyphae compared to yeast-form cells; fluconazole or flucytosine induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1165272 1167102 + orf19.6882 1165272 1167102 1 1165272 1167102 1165501 1167012 OSM1 orf19.14171|IPF20231.1|IPF9550.1|Contig4-3086_0042|orf6.7146|CA4570|CaO19.14171|CaO19.6882|IPF9550 Putative flavoprotein subunit of fumarate reductase; soluble protein in hyphae; fungal-specific (no human or murine homolog); caspofungin repressed; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1166955 1168213 - orf19.6882.1 1166955 1168213 2 1168213|1167600 1168057|1166955 1168075 1167296 IPF20254.1|IPF9548.1|Contig4-3086_0043|CA4571|RPL33|RPL33.3 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1168432 1170127 - orf19.6883 1168432 1170127 1 1170127 1168432 1169839 1168547 orf19.14172|IPF20234.1|IPF9434.2|orf6.7147|CA4572|CaO19.6883|KES1|CaO19.14172 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1170218 1172256 - orf19.6884 1170218 1172256 1 1172256 1170218 1171859 1170402 orf19.14173|IPF20233.1|IPF9431.1|Contig4-2670_0004|orf6.7148|CA4573|GWT1|CaO19.6884|CaO19.14173|IPF9431 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1172364 1174269 + orf19.6885 1172364 1174269 1 1172364 1174269 1172595 1174139 SPO7 orf19.14174|IPF20230.1|IPF9430.2|Contig4-2670_0007|orf6.7149|CA4574|CaO19.6885|CaO19.14174|IPF9430 Protein similar to S. cerevisiae Spo7p; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1174575 1176053 + orf19.6886 1174575 1176053 1 1174575 1176053 1174647 1175897 orf19.14175|IPF20235.1|IPF9428.2|Contig4-2670_0008|orf6.7150|CA4575|CaO19.6886|CaO19.14175|IPF9428 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1175855 1176487 - orf19.6887 1175855 1176487 1 1176487 1175855 1176415 1176083 orf19.14176|orf6.7151|CaO19.14176|CaO19.6887 Predicted ORF from Assembly 19; repressed by nitric oxide; removed from Assembly 20; subsequently reinstated in Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1178328 1179952 + orf19.6888 1178328 1179952 2 1178328|1178504 1178393|1179952 1178328 1179766 orf19.14177|orf6.7152|IPF19437.2|IPF9425.2|Contig4-2509_0013|Contig4-2670_0012|orf6.122|CA4576|CaO19.6888|ZFU3|IPF9425.3 Protein with Gal4p-like DNA-binding domain; gene transcription regulated by Mig1p and Tup1p [label_first_exon=CGD label_last_exon=CGDmod orf_changed=false scenario_first_exon=Z scenario_last_exon=G] Ca21chr2 1180400 1182050 - orf19.6889 1180400 1182050 1 1182050 1180400 1181854 1180514 MKK2 orf19.14178|IPF9424.3|IPF14309.2|Contig4-2509_0011|orf6.121|orf6.7153|CA4577|CaO19.6889 Protein not essential for viability; similar to S. cerevisiae Mkk2p, which is a MAP kinase kinase involved in signal transduction; macrophage-downregulated gene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1182464 1185333 - orf19.6891 1182464 1185333 2 1185333|1185190 1185256|1182464 1185303 1182572 RFC1 orf19.14180|IPF19208.2|IPF14308.2|Contig4-2509_0005|Contig4-2509_0007|orf6.632|orf6.7155|CA4578 Protein likely to be essential for growth, based on an insertional mutagenesis strategy; similar to S. cerevisiae Rfc1, which is a subunit of DNA replication factor C [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1185723 1187304 - orf19.6893 1185723 1187304 1 1187304 1185723 1187214 1185853 orf19.14182|IPF17098.1|IPF14300.2|Contig4-2509_0001|orf6.630|orf6.7157|orf6.7158|CA6307|CA0139|orf19.6894|RUD3.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1189226 1190956 + orf19.5204 1189226 1190956 1 1189226 1190956 1189319 1190956 orf19.12671|orf19.14183|IPF22006.1|IPF13971.2|IPF20250.1|IPF18198.1|Contig4-2237_0001|orf6.3447|orf6.7159|CA1790|orf19.6895|CaO19.12671|CaO19.5204|IPF13971 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chr2 1191685 1193410 + orf19.5205 1191685 1193410 1 1191685 1193410 1191791 1193236 orf19.12672|IPF22008.1|IPF13967.2|Contig4-2237_0004|orf6.3448|CA1791|CaO19.5205|CaO19.12672|IPF13967 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 1192756 1194832 - orf19.5206 1192756 1194832 1 1194832 1192756 1194799 1193270 orf19.12673|IPF22007.1|IPF13966.2|Contig4-2237_0005|orf6.3449|CA1792|CaO19.12673|CaO19.5206|IPF13966 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1194941 1196453 + orf19.5207 1194941 1196453 1 1194941 1196453 1194984 1196264 orf19.12674|orf19.12675|IPF22014.1|IPF22015.1|IPF18608.1|Contig4-3052_0031|orf6.3450|orf6.3451|CA1793|CA1794|orf19.5208|IPF18608.5f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1196131 1198624 - orf19.5209 1196131 1198624 1 1198624 1196131 1198572 1196257 orf19.12676|IPF21999.1|IPF11261.2|Contig4-3052_0001|orf6.3452|CA1795|COG6|CaO19.12676|CaO19.5209|IPF11261 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1198860 1200667 - orf19.5210 1198860 1200667 1 1200667 1198860 1200658 1198925 orf19.12677|IPF22005.1|IPF11259.2|Contig4-3052_0003|orf6.3453|CA1796|CaO19.5210|XBP1|CaO19.12677|IPF11259 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1200847 1201081 - ntar_397 1200847 1201081 1 1201081 1200847 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1204022 1204562 + orf19.5210.1 1204022 1204562 2 1204022|1204394 1204330|1204562 1204193 1204522 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1204447 1205923 - orf19.5211 1204447 1205923 1 1205923 1204447 1205852 1204551 IDP1 orf19.12678|IPF22009.1|IPF5863.2|Contig4-3052_0006|Contig4-3052_0007|orf6.3902|CA2131|CaO19.5211|CaO19.12678 Protein described as isocitrate dehydrogenase; transcriptionally induced by interaction with macrophage; alkaline upregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1206499 1207661 + orf19.5212 1206499 1207661 2 1206499|1206703 1206640|1207661 1206499 1207661 orf19.12679|IPF22011.1|IPF5865.2|Contig4-3052_0008|orf6.3903|CA2132|IPF5865 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1208069 1211114 + orf19.5213 1208069 1211114 1 1208069 1211114 1208528 1210972 orf19.12680|IPF21998.1|IPF5866.2|Contig4-3052_0009|orf6.3904|CA2133|CaO19.12680|CaO19.5213|IPF5866 Putative protein of unknown function, transcription is upregulated in clinical isolates from HIV+ patients with oral candidiasis; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1211037 1211577 - orf19.5213.1 1211037 1211577 1 1211577 1211037 1211519 1211238 COX8 IPF22018.1|IPF5867.1|Contig4-3052_0010|CA2134 ORF Predicted by Annotation Working Group; flucytosine induced; caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1211829 1212297 + orf19.5213.2 1211829 1212297 1 1211829 1212297 1211893 1212078 COX9 orf19.12680.2|IPF22003.1|IPF5868.1|Contig4-3052_0012|CA2135 Putative subunit VIIa of cytochrome c oxidase; flucytosine induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1212198 1214457 - orf19.5214 1212198 1214457 1 1214457 1212198 1214402 1212306 VPS33 orf19.12681|IPF22002.1|IPF5870.2|Contig4-3052_0015|Contig4-3052_0016|orf6.3905|CA2136|CaO19.12681|CaO19.5214 Predicted ORF in Assemblies 19, 20 and 21; similar to S. cerevisiae Vps33p, which is the product of a class C vacuolar protein sorting (vps) gene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1214644 1215805 - orf19.5215 1214644 1215805 1 1215805 1214644 1215750 1214689 TES15 orf19.12682|IPF22010.1|IPF5871.2|Contig4-3052_0018|orf6.3906|CA6220|CaO19.5215|TES5|CaO19.12682 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1216054 1217144 - orf19.5216 1216054 1217144 1 1217144 1216054 1217011 1216115 orf19.12683|IPF22013.1|IPF5873.2|Contig4-3052_0020|orf6.3907|CA6221|TES4|CaO19.5216|CaO19.12683|TES14 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1217465 1218735 - orf19.5217 1217465 1218735 1 1218735 1217465 1218631 1217735 TES1 orf19.12684|IPF22012.1|IPF5876.2|Contig4-3052_0022|orf6.3908|CA6222|CaO19.5217|TES3|CaO19.12684|TES13 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1219063 1220235 - orf19.4122 1219063 1220235 1 1220235 1219063 1220133 1219153 orf19.12685|orf19.11605|IPF23166.1|IPF5877.2|IPF22017.1|IPF18535.1|Contig4-3052_0024|orf6.3191|orf6.3909|CA1608|orf19.5218|TES2|CaO19.4122|TES12 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1221356 1222701 - orf19.4121 1221356 1222701 1 1222701 1221356 1222609 1221455 orf19.11603|IPF23150.1|IPF5879.2|Contig4-3052_0027|orf6.3192|CA1609|TES1|CaO19.11603|CaO19.4121|TES11 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1223164 1224899 + orf19.4120 1223164 1224899 1 1223164 1224899 1223378 1224856 LAS1 orf19.11602|IPF23142.1|IPF5882.2|Contig4-3052_0028|orf6.3193|CA1610|CaO19.4120|CaO19.11602 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU); macrophage-induced gene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1225226 1231170 + orf19.4119 1225226 1231170 1 1225226 1231170 1225442 1231012 SPO72 orf19.11601|IPF23167.1|IPF12198.2|Contig4-2495_0008|orf6.3194|CA1611|ATG2|CaO19.4119|CaO19.11601 Protein similar to S. cerevisiae sporulation protein; up-regulation associated with azole resistance [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 1232558 1234668 + orf19.4118 1232558 1234668 1 1232558 1234668 1232842 1234668 CNT orf19.11600|NNT1|IPF12201|IPF12201.2|IPF2129.3|Contig4-2495_0005|orf6.6818|orf6.804|CA0189|NNT99|CaO19.4118 Cation-coupled nucleoside transporter (H(+)/nucleoside symporter); CNT family; transports adenosine, uridine, inosine, guanosine, tubercidin; variant alleles encode high- and low-affinity isoforms; S or G at residue 328 affects specificity [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1234865 1236445 + orf19.4117 1234865 1236445 1 1234865 1236445 1234911 1236344 orf19.11599|IPF2127.3|IPF23159.1|IPF2127.2|Contig4-2528_0002|orf6.6819|orf6.805|CA4309|CaO19.4117 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1236255 1237905 - orf19.4116 1236255 1237905 1 1237905 1236255 1237627 1236356 orf19.11597|IPF2125|IPF23145.1|IPF2125.2|Contig4-2528_0003|orf6.6820|CA4310|CaO19.4116|CaO19.11597 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1237930 1238003 - tm(cau)3 1237930 1238003 1 1238003 1237930 tM(CAU)3.2 tRNA-Met predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1238541 1238873 - orf19.4115 1238541 1238873 1 1238873 1238541 1238873 1238541 orf19.11596|IPF23175.1|IPF28528.1|Contig4-2528_0004|orf6.6821|CaO19.11596|CaO19.4115 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1239011 1241424 + orf19.4114 1239011 1241424 1 1239011 1241424 1239137 1241290 FAA2-1 orf19.11595|IPF23135.1|IPF2123.2|Contig4-2528_0006|orf6.6822|CA4311|FAA23|CaO19.4114|FAA22|CaO19.11595 Predicted long chain fatty acid CoA ligase; upregulated upon phagocytosis; induced by nitric oxide in yhb1 mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1241349 1242562 - orf19.4112 1241349 1242562 1 1242562 1241349 1242471 1241554 orf19.11593|IPF23154.1|IPF2122.2|Contig4-2528_0007|orf6.6824|CA4312|CaO19.11593|CaO19.4112|IPF2122 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1242653 1245923 + orf19.4110 1242653 1245923 1 1242653 1245923 1242656 1245784 orf19.11591|IPF23186.1|IPF2121.2|Contig4-2950_0020|orf6.6826|CA4313|CaO19.4110|CaO19.11591|IPF2121 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1246095 1248544 + orf19.4109 1246095 1248544 1 1246095 1248544 1246154 1248421 PMT4 orf19.11590|IPF23133.1|IPF2115.1|Contig4-2950_0002|orf6.6827|CA4314|CaO19.4109|CaO19.11590 Protein mannosyltransferase required for normal cell wall composition and full virulence in mouse systemic infection; has roles in hyphal growth and drug sensitivity; one of 5 PMT family members; Axl2p is a substrate [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1248635 1250131 + orf19.4107 1248635 1250131 1 1248635 1250131 1248733 1249938 orf19.11588|IPF23148.1|IPF2112.1|Contig4-2950_0003|orf6.6829|CA4315|CaO19.11588|PPX1|CaO19.4107 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1249637 1250990 - orf19.4106 1249637 1250990 1 1250990 1249637 1250990 1249944 orf19.11587|IPF23151.1|IPF2111.1|Contig4-2950_0005|orf6.6830|CA4316|CaO19.4106|CaO19.11587|IPF2111 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr2 1251151 1252265 + orf19.4105 1251151 1252265 1 1251151 1252265 1251180 1252130 orf19.11586|IPF23153.1|IPF2109.1|Contig4-2950_0006|orf6.6831|CA4317|CaO19.4105|CaO19.11586|IPF2109 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1252155 1253759 - orf19.4104 1252155 1253759 1 1253759 1252155 1253759 1252155 orf19.11585|IPF23140.1|IPF2106.2|Contig4-2950_0009|orf6.6832|CA4318|CaO19.11585|CaO19.4104|IPF2106 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1253966 1254973 - orf19.4102 1253966 1254973 1 1254973 1253966 1254864 1254025 RPN10 orf19.11583|IPF23155.1|IPF2104.2|Contig4-2950_0011|orf6.6834|CA4319|CaO19.11583|CaO19.4102 Predicted ORF in Assemblies 19, 20 and 21; macrophage/pseudohyphal-repressed; regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1255116 1255670 + orf19.4101 1255116 1255670 1 1255116 1255670 1255179 1255487 orf19.11582|IPF23185.1|IPF2103.1|Contig4-2950_0015|orf6.6835|CaO19.11582|CaO19.4101 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1255595 1260098 - orf19.4099 1255595 1260098 1 1260098 1255595 1260036 1255723 ECM17 orf19.11580|orf19.12932|MET5|IPF23129.1|IPF2102.1|IPF21658.1|IPF13588.2|Contig4-2950_0017|orf6.6837|orf6.4171|CA4320|orf19.5477|CaO19.4099|CaO19.11580 Predicted enzyme of sulfur amino acid biosynthesis; putative role in regulation of cell wall biogenesis; upregulated in biofilm; possibly adherence-induced; regulated by Tsa1p, Tsa1Bp under H2O2 stress; Gcn4p-regulated; Tbf1p-activated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1260637 1261785 - orf19.5479 1260637 1261785 1 1261785 1260637 1261785 1260637 FGR12 orf19.12934|IPF21669.1|IPF13586.2|Contig4-2950_0018|orf6.4173|CA2317|CaO19.12934|CaO19.5479|IPF13586 [NOT TRANSCRIBED?] Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1262881 1264865 + orf19.5480 1262881 1264865 1 1262881 1264865 1262982 1264691 ILV1 orf19.12935|IPF21664.1|IPF16147.2|orf6.4174|CA2318|CaO19.5480|CaO19.12935 Protein described as threonine dehydratase; regulated by Gcn4p and Gcn2p; induced in response to amino acid starvation (3-aminotriazole treatment); protein detected by mass spec in both exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1264634 1266784 - orf19.5483 1264634 1266784 1 1266784 1264634 1266764 1264800 orf19.12938|IPF21662.1|IPF19755.1|Contig4-2604_0002|orf6.4177|CA2319|CaO19.5483|GUF1|CaO19.12938 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1266791 1268221 - orf19.5484 1266791 1268221 1 1268221 1266791 1268118 1266940 SER1 orf19.12939|IPF21668.1|IPF10985.1|Contig4-2604_0003|orf6.4178|CA2320|CaO19.12939|CaO19.5484 Predicted ORF in Assemblies 19, 20 and 21; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1268292 1269454 - orf19.5485 1268292 1269454 1 1269454 1268292 1269317 1268358 MEC3 orf19.12940|IPF21670.1|IPF10984.1|Contig4-2604_0005|orf6.4179|CA2321|CaO19.12940|CaO19.5485 Increased transcription is observed upon benomyl treatment [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1268355 1269089 + ntar_398 1268355 1269089 1 1268355 1269089 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1269397 1272052 + orf19.5486 1269397 1272052 1 1269397 1272052 1269397 1272009 orf19.12941|IPF21656.1|IPF10981.1|Contig4-2604_0006|orf6.4180|CA2322|CaO19.12941|YSH1|CaO19.5486 Putative protein of unknown function; heterozygous null mutant exhibits hypersensitivity to parnafungin and cordycepin in the C. albicans fitness test; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1272120 1272674 + orf19.5486.1 1272120 1272674 2 1272120|1272286 1272208|1272674 1272204 1272619 SMD2 IPF21683.1|IPF10980.2|Contig4-2604_0007|CA2323 ORF Predicted by Annotation Working Group; flucytosine induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1272629 1275020 - orf19.5487 1272629 1275020 1 1275020 1272629 1274900 1272714 CDC46 orf19.12942|IPF21660.1|IPF10979.2|Contig4-2604_0008|orf6.4181|CA2324|MCM5|CaO19.5487|CaO19.12942 Protein described as having role in control of cell division; periodic mRNA expression, peak at cell-cycle M/G1 phase; regulated by tyrosol and cell density; Plc1p-regulated; repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1275206 1275970 + orf19.5488 1275206 1275970 1 1275206 1275970 1275300 1275815 orf19.12943|IPF21677.1|IPF10977.2|Contig4-2604_0010|orf6.4182|CA2325|CaO19.12943|CaO19.5488|IPF10977 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1276040 1277236 + orf19.5489 1276040 1277236 1 1276040 1277236 1276040 1277236 orf19.12944|orf19.12945|IPF21675.1|IPF5831.2|IPF5832.3|IPF5833.2|Contig4-2947_0024|Contig4-2947_0026|orf6.4183|orf6.4184|orf6.4667|orf19.5490|CaO19.5489|CaO19.12944 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction); merged with orf19.5490 in Assembly 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1276539 1278440 - orf19.5491 1276539 1278440 1 1278440 1276539 1278420 1277233 orf19.12946|IPF5834.2|IPF28015.1|Contig4-2947_0022|orf6.4185|orf6.4666|CA2678|CaO19.5491|IPF5834 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 1278572 1279615 - orf19.5491.1 1278572 1279615 2 1279615|1279059 1279435|1278572 1279452 1278751 ATP14 IPF21688.1|IPF5835.2|Contig4-2947_0021|CA2677|ATP14.exon2 ORF Predicted by Annotation Working Group; macrophage/pseudohyphal-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1279749 1280489 + orf19.5492 1279749 1280489 1 1279749 1280489 1279836 1280288 orf19.12947|IPF21681.1|IPF5838.1|Contig4-2947_0019|orf6.4665|CA2676|CaO19.12947|YHC1|CaO19.5492 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1280448 1281446 - orf19.5493 1280448 1281446 1 1281446 1280448 1281391 1280747 GSP1 orf19.12948|orf6.4664|IPF21672.1|IPF5839.2|Contig4-2947_0017|CA2675|CaO19.5493|CaO19.12948 Small RAN G-protein; essential; prenylation not predicted; overproduction complements viability of S. cerevisiae gsp1 mutant; macrophage/pseudohyphal-induced; not transcriptionally regulated during white-opaque or yeast-hyphal switching [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1285008 1288717 + orf19.5495 1285008 1288717 1 1285008 1288717 1285343 1288609 orf19.12950|IPF5846|IPF21686.1|IPF5846.1|Contig4-2947_0012|orf6.4662|CA2674|CaO19.5495|CaO19.12950 Protein not essential for viability; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1288873 1290753 - orf19.5496 1288873 1290753 1 1290753 1288873 1290576 1288969 AVT1 orf19.12951|IPF21666.1|IPF5849.1|Contig4-2947_0008|Contig4-2947_0010|orf6.4661|CA2673|AVT12|CaO19.5496|CaO19.12951|IPF5849 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1295452 1297614 + orf19.5498 1295452 1297614 1 1295452 1297614 1295452 1297614 EFH1 orf19.12953|IPF21661.1|IPF5855.2|Contig4-2947_0001|orf6.4659|CA2672|PHD1|CaO19.5498|CaO19.12953 Transcriptional activator; minor role in transcriptional regulation, compared to Efg1p; regulates filamentous growth, phenotypic switching; homodimerizes; has APSES domain and acidic region; EFG1 and EFH1 genetically interact [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1297898 1299340 - orf19.5499 1297898 1299340 1 1299340 1297898 1299340 1297898 orf19.12954|IPF21663.1|IPF5856.2|orf6.4658|CA2671|CaO19.5499|HPD99|CaO19.12954|IPF5856 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1299982 1301074 - orf19.5500 1299982 1301074 1 1301074 1299982 1301008 1300061 MAK16 orf19.12955|IPF21671.1|IPF5859.3|Contig4-1385_0002|Contig4-1385_0003|orf6.4657|CA2670|CaO19.12955|CaO19.5500|IPF5859.2 Predicted ORF in Assemblies 19, 20 and 21; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1301213 1301942 - orf19.17 1301213 1301942 1 1301942 1301213 1301909 1301325 SCP1 orf19.7688|IPF3874.2|IPF29979.1|CA6167|CaO19.17 Predicted ORF in Assemblies 19, 20 and 21; constitutive expression independent of MTL or white-opaque status [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1302279 1304262 - orf19.18 1302279 1304262 2 1304262|1303454 1303702|1302279 1304152 1302340 IMH3 orf19.7689|orf19.7690|IPF3873.2|IPF27224.1|IPF29977.1|IPF3872.2|orf6.2651|orf6.2652|CA1246|orf19.19|IMD3|CA1245|IMH3.exon2|IMH3.exon1 Inosine monophosphate (IMP) dehydrogenase; enzyme of GMP biosynthesis; target of mycophenolic acid and mizoribine monophosphate; antigenic during human or murine infection; soluble protein in hyphae; downregulated in core stress response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1304498 1305034 - ntar_399 1304498 1305034 1 1305034 1304498 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1305469 1308672 - orf19.20 1305469 1308672 1 1308672 1305469 1308223 1305671 RTS1 orf19.7691|IPF27207.1|IPF3870.2|Contig4-3047_0003|orf6.2653|CA1247|CaO19.7691|CaO19.20|IPF3870 Transcription is regulated upon yeast-hyphal switch [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1309292 1310574 - orf19.21 1309292 1310574 1 1310574 1309292 1310415 1309828 orf19.7692|IPF3866.2|IPF29978.1|Contig4-3047_0007|orf6.2654|CA1248|SYM1|CaO19.21|CaO19.7692|IPF3866 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1310594 1311612 - orf19.22 1310594 1311612 1 1311612 1310594 1311518 1310784 orf19.7693|orf6.5916|IPF18727.2|IPF3865.2|Contig4-3047_0009|orf6.2655|CA3605|CaO19.22|CaO19.7693|IPF3865 Transcription is positively regulated by Sfu1p; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1312455 1313376 - orf19.22.1 1312455 1313376 1 1313376 1312455 1313376 1313245 Pseudogene; added to Assembly 21 based on comparative genome analysis [label_first_exon=CGD label_last_exon=CGD orf_changed=true scenario_first_exon=E scenario_last_exon=E] Ca21chr2 1314793 1316527 + orf19.23 1314793 1316527 1 1314793 1316527 1314829 1316223 RTA3 orf19.7694|YOR49|Contig4-3047_0020|IPF27215.1|IPF3859.1|orf6.5917|CA3606|CaO19.7694|RSB13|CaO19.23 Similar to S. cerevisiae Rta1p (role in 7-aminocholesterol resistance) and Rsb1p (flippase); putative membrane protein; putative drug-responsive regulatory site; induced by fluphenazine, estradiol, ketoconazole, caspofungin [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1317012 1318635 + orf19.24 1317012 1318635 1 1317012 1318635 1317228 1318589 RTA2 orf19.7695|IPF27216.1|IPF3858.1|Contig4-3047_0022|orf6.5918|CA3607|CaO19.24|RSB11|CaO19.7695 Putative floppase; required for sphingolipid long chain base release; mediates calcineurin-dependent resistance to azoles; stress-associated protein; Ca2+, calcineurin-regulated; ketoconazole, caspofungin induced; Plc1p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1318251 1318525 - ntar_400 1318251 1318525 1 1318525 1318251 1318465 1318298 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1318764 1319825 + orf19.25 1318764 1319825 1 1318764 1319825 1318802 1319773 orf19.7696|IPF27221.1|IPF3857.1|Contig4-3047_0024|orf6.5919|CA3608|CaO19.25|TRM10|CaO19.7696|IPF3857 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1319941 1321285 + orf19.26 1319941 1321285 1 1319941 1321285 1320001 1321188 orf19.7697|IPF3856.1|Contig4-3047_0025|orf6.5920|CA3609|PNG1|CaO19.7697|CaO19.26|IPF3856 Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide in yhb1 mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1321524 1321610 + ti(aau)1 1321524 1321610 2 1321524|1321575 1321561|1321610 tI(AAU)1.2 tRNA-Ile predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1321782 1323275 + orf19.27 1321782 1323275 2 1321782|1321998 1321934|1323275 1321872 1323179 orf19.7698|IPF27218.1|IPF3854.1|Contig4-3047_0026|orf6.5921|CA3610|CaO19.7698|CaO19.27|IPF3854 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1323140 1324209 - orf19.28 1323140 1324209 1 1324209 1323140 1324126 1323221 orf19.7699|IPF27222.1|IPF3853.1|Contig4-3047_0028|orf6.5922|CA3611|CaO19.7699|TPC1|CaO19.28|IPF3853 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1324472 1325671 + orf19.29 1324472 1325671 1 1324472 1325671 1324614 1325585 orf19.7700|IPF27220.1|IPF3852.2|Contig4-3047_0029|orf6.5923|CA3612|CaO19.29|CaO19.7700|IPF3852 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1325625 1329456 - orf19.30 1325625 1329456 1 1329456 1325625 1329398 1325727 orf19.7701|IPF27225.1|IPF3849.2|Contig4-1545_0001|orf6.5924|CA3613|CaO19.7701|SPF1|CaO19.30 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1329655 1331921 + orf19.31 1329655 1331921 1 1329655 1331921 1330987 1331742 orf19.7702|IPF27223.1|IPF8878.1|Contig4-2679_0003|orf6.5925|CA3614|CaO19.7702|CIS302|CaO19.31|IPF8878 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1332397 1333426 - ntar_401 1332397 1333426 1 1333426 1332397 1332952 1332647 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1332535 1333254 + ntar_402 1332535 1333254 1 1332535 1333254 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1333727 1334061 + ntar_403 1333727 1334061 1 1333727 1334061 1333727 1333990 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1334306 1335865 - orf19.34 1334306 1335865 1 1335865 1334306 1335865 1334306 orf19.7705|orf6.5928|IPF18890.2|IPF8874.2|Contig4-2679_0007|orf6.1824|GIT1|CA3615|CaO19.34 Putative permease of glycerophosphoinositol import; fungal-specific (no human or murine homolog); transcription is negatively regulated by Rim101p; virulence-group-correlated expression [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr2 1334617 1334939 + ntar_404 1334617 1334939 1 1334617 1334939 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1335175 1335896 + ntar_405 1335175 1335896 1 1335175 1335896 1335175 1335300 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1338354 1338530 - ntar_406 1338354 1338530 1 1338530 1338354 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1340755 1344452 + orf19.35 1340755 1344452 1 1340755 1344452 1341035 1344079 orf19.7708|IPF13398.2|IPF19358.2|Contig4-2637_0007|Contig4-2637_0009|Contig4-2637_0013|orf6.1821|orf6.286|CA0724|SKY2|CaO19.35|IPF13398 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1344430 1344831 - ntar_407 1344430 1344831 1 1344831 1344430 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1345070 1345723 + ntar_408 1345070 1345723 1 1345070 1345723 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1345203 1345445 - orf19.35.1 1345203 1345445 1 1345445 1345203 1345445 1345203 [NOT TRANSCRIBED?] ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1346906 1348705 + orf19.36 1346906 1348705 1 1346906 1348705 1347014 1348291 orf19.7709|IPF27217.1|IPF13402.1|Contig4-2637_0001|orf6.608|CA0131|CaO19.7709|COG8|CaO19.36|IPF13402 Predicted ORF in Assemblies 19, 20 and 21; clade-associated gene expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1348588 1349050 - ntar_409 1348588 1349050 1 1349050 1348588 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1349755 1350211 - orf19.36.1 1349755 1350211 1 1350211 1349755 1350101 1349895 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1350873 1354374 - orf19.1295 1350873 1354374 1 1354374 1350873 1354350 1350991 VAS1 orf19.8875|IPF26041.1|IPF13980.2|Contig4-1984_0003|orf6.295|orf6.921|CA0223|CaO19.1295 Putative tRNA-Val synthetase; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1354596 1356462 - orf19.1296 1354596 1356462 1 1356462 1354596 1356380 1354671 orf19.8876|IPF26039.1|IPF13982.2|orf6.922|CA0224|orf19.82|CaO19.8876|PRP31|CaO19.1296 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 1356590 1357476 + orf19.81 1356590 1357476 1 1356590 1357476 1356640 1357449 Contig4-2678_0013|RRP46|CaO19.81 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1357787 1360292 - orf19.1223 1357787 1360292 1 1360292 1357787 1360034 1357902 DBF2 orf19.8809|IPF26112.1|IPF13853.2|Contig4-1569_0001|orf6.851|CA0205|CaO19.8809|CaO19.1223 Essential serine/threonine protein kinase involved in mitotic spindle formation and cytokinesis; required for septum formation, exit from mitosis, and normal hyphal morphogenesis; virulence-group-correlated expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1360849 1361141 + ntar_410 1360849 1361141 1 1360849 1361141 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1363018 1363746 - ntar_411 1363018 1363746 1 1363746 1363018 1363433 1363296 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1364081 1364265 - ntar_412 1364081 1364265 1 1364265 1364081 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1364998 1366305 + orf19.1224 1364998 1366305 1 1364998 1366305 1365218 1366075 FRP3 orf19.8810|IPF13846.3|IPF16160.1|Contig4-2326_0009|orf6.1315|orf6.361|CA0415|AFF1|CaO19.1224 Upregulated in the presence of human neutrophils; fluconazole-downregulated; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1365324 1365655 - ntar_413 1365324 1365655 1 1365655 1365324 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1366723 1367815 - orf19.1225 1366723 1367815 1 1367815 1366723 1367676 1367053 orf19.8811|IPF26113.1|IPF17492.2|Contig4-2326_0011|orf6.1316|CA0416|CaO19.1225|IPF17492 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1368033 1368182 - ntar_414 1368033 1368182 1 1368182 1368033 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1368172 1368440 + ntar_415 1368172 1368440 1 1368172 1368440 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1368286 1368456 - ntar_416 1368286 1368456 1 1368456 1368286 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1368934 1369590 + ntar_417 1368934 1369590 1 1368934 1369590 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1369866 1370269 + ntar_418 1369866 1370269 1 1369866 1370269 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1370217 1370606 - ntar_419 1370217 1370606 1 1370606 1370217 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1371575 1373800 + orf19.3152 1371575 1373800 1 1371575 1373800 1371756 1373771 AMO2 orf19.10662|IPF24146.1|IPF15803.2|orf6.1742|CA0673|CaO19.3152|CaO19.10662|CA0145|IPF11449|IPF11449.1|IPF15803.1 Protein similar to A. niger predicted peroxisomal copper amino oxidase; mutation confers hypersensitivity to toxic ergosterol analog; induced upon biofilm formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1374507 1375872 + orf19.3151 1374507 1375872 1 1374507 1375872 1374602 1375768 orf19.10661|Contig4-2902_0012|IPF24148.1|IPF15804.2|orf6.1741|CA0672|CaO19.3151|CaO19.10661|GRP6 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1375822 1375994 - ntar_420 1375822 1375994 1 1375994 1375822 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1376208 1377575 + orf19.3150 1376208 1377575 1 1376208 1377575 1376462 1377499 GRE2 orf19.10660|orf6.1740|Contig4-2831_0003|GRP4|IPF15555.2|IPF28876.1|CA0671|CaO19.3150|GRE23|CaO19.10660 Protein described as a reductase; transcription is regulated by Nrg1p and Tup1p; benomyl-induced; hyphal-induced; macrophage/pseudohyphal-repressed; expression greater in low iron; reported to be involved in osmotic stress response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1377438 1378626 - ntar_421 1377438 1378626 1 1378626 1377438 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1378021 1378295 + ntar_422 1378021 1378295 1 1378021 1378295 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1379374 1380783 + orf19.3149 1379374 1380783 1 1379374 1380783 1379510 1380463 LSP1 orf19.10659|IPF15552.2|IPF14171.2|Contig4-2831_0005|orf6.1659|CA0622|SLB2|CaO19.3149|CaO19.10659|IPF14171 Predicted ORF in Assemblies 19, 20 and 21; caspofungin repressed; biofilm induced; fungal-specific (no human or murine homolog); protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1382161 1382403 - ntar_423 1382161 1382403 1 1382403 1382161 1382331 1382161 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1383122 1385985 + orf19.3148 1383122 1385985 1 1383122 1385985 1383313 1385898 orf19.10658|IPF14168.3|IPF17999.2|Contig4-2831_0010|Contig4-2831_0011|orf6.1658|orf6.19|CA0621|CaO19.3148|IPF17999 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 1386116 1387078 - orf19.3147 1386116 1387078 1 1387078 1386116 1387030 1386290 orf19.10657|IPF24149.1|IPF17998.2|orf6.1657|CA0620|CaO19.3147|IPF17998 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1387415 1388952 - orf19.2227 1387415 1388952 1 1388952 1387415 1388799 1387549 orf19.10656|orf19.9769|IPF25081.1|IPF9051.2|IPF18923.2|IPF18924.1|Contig4-2341_0001|orf6.1320|orf6.1656|CA0418|CA0619|orf19.3146|CaO19.2227|STC99|CaO19.9769|IPF9051.5eoc Predicted ORF in Assemblies 19, 20 and 21; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1389102 1390562 + orf19.2228 1389102 1390562 1 1389102 1390562 1389157 1390380 orf19.9770|IPF25058.1|IPF19864.1|Contig4-2341_0006|orf6.1321|CA0419|CaO19.2228|TWF1|CaO19.9770|IPF19864 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1390436 1392220 - orf19.2229 1390436 1392220 1 1392220 1390436 1392124 1390478 orf19.9771|IPF25048.1|IPF9048.1|Contig4-2341_0007|orf6.1322|CA0420|CaO19.2229|CaO19.9771|IPF9048 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1392276 1392986 + orf19.2230 1392276 1392986 1 1392276 1392986 1392405 1392764 orf19.9772|IPF25091.1|IPF9047.1|IPF9047|Contig4-2341_0009|orf6.1323|CA0421|CaO19.9772|CaO19.2230 Decreased transcription is observed upon benomyl treatment [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1392803 1394144 - orf19.2231 1392803 1394144 1 1394144 1392803 1393616 1392837 orf19.9773|IPF25069.1|IPF9046.1|Contig4-2341_0010|orf6.1324|CA0422|CaO19.2231|CaO19.9773|IPF9046 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1395032 1395289 + ntar_424 1395032 1395289 1 1395032 1395289 1395032 1395190 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1395424 1396672 - orf19.2232 1395424 1396672 2 1396672|1396123 1396517|1395424 1396519 1395602 RPL11 orf19.9774|IPF25080.1|IPF9044.1|RPL11B|Contig4-2838_0014|orf6.1888|CA0763 Predicted ribosomal protein; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage; colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1396815 1397827 - orf19.2233 1396815 1397827 1 1397827 1396815 1397736 1396879 PRE2 orf19.9775|IPF25065.1|IPF9042.1|Contig4-2838_0012|orf6.1889|CA0764|CaO19.2233|CaO19.9775 Protein described as beta-5 subunit of proteasome; macrophage-induced protein [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1398009 1401876 - orf19.2236 1398009 1401876 1 1401876 1398009 1401601 1398143 orf19.9778|orf6.1892|IPF9040.3|IPF29164.1|Contig4-2838_0010|orf6.2396|CA0765|FHL1|CaO19.2236|IPF9040|IPF9040.3eoc|IPF9040.2 Protein with forkhead domain; similar to Fhl1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1402483 1404060 + orf19.2237 1402483 1404060 1 1402483 1404060 1402483 1404060 SPR1 orf19.9779|IPF25049.1|IPF19900.1|Contig4-2838_0007|Contig4-2838_0008|orf6.2395|CA1078|CaO19.2237|CaO19.9779 [NOT TRANSCRIBED?] Putative GPI-anchored protein; not essential for viability; similar to S. cerevisiae Spr1p, which is a sporulation-specific exo-1,3-beta-glucanase [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1404335 1405431 + orf19.2237.1 1404335 1405431 2 1404335|1404449 1404374|1405431 1404372 1405051 CA6201|IPF13696|orf19.9779.1 Predicted ORF in Assembly 20 and 21; gene has intron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1404975 1405387 - ntar_425 1404975 1405387 1 1405387 1404975 1405161 1405030 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1406377 1406698 - ntar_426 1406377 1406698 1 1406698 1406377 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1407128 1412407 + orf19.2238 1407128 1412407 1 1407128 1412407 1407349 1412304 LTE1 orf19.9780|orf19.9781|IPF25036.1|IPF13694.2|IPF25034.1|IPF19721.1|Contig4-2781_0024|Contig4-2838_0001|Contig4-2838_0002|orf6.2394|orf6.2393|CA1077|CA1076|orf19.2239|CaO19.9780|LTE99|CaO19.2238|IPF13694 Protein similar to S. cerevisiae Lte1p; transcription is repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1412405 1413598 - orf19.2241 1412405 1413598 1 1413598 1412405 1413266 1412670 PST1 IPF17954.2|IPF18769.1|Contig4-2561_0001|orf6.1034|orf6.2391|CA6202|IPF18769 Protein described as 1,4-benzoquinone reductase; biofilm induced; hyphal-induced expression, regulated by Cyr1p, Ras1p, Efg1p, Nrg1p, Rfg1p, Tup1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1413904 1415464 - orf19.2242 1413904 1415464 1 1415464 1413904 1415365 1413968 PRB1 orf19.9783|orf6.1035|PRB2|IPF12896.2|IPF29156.1|Contig4-2561_0002|orf6.2390|CA0270|CaO19.2242|PRB11 Putative endoprotease B; regulated by heat, carbon source (GlcNAc-induced), nitrogen, macrophage response, human neutrophils; putative D200-H232-S389 catalytic triad; similar to (but does not replace) S. cerevisiae vacuolar B protease Prb1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1415533 1416799 - orf19.2244 1415533 1416799 1 1416799 1415533 1416704 1415745 orf19.9785|orf6.1037|IPF12897.2|IPF29158.1|Contig4-2561_0004|CA0271|CaO19.9785|CaO19.2244|IPF12897 Similar to oxidoreductases and to S. cerevisiae Yjr096wp; transcription is negatively regulated by Sfu1p; increased transcription is observed upon benomyl treatment; decreased expression observed in an ssr1 homozygous null mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1417314 1418481 + orf19.2245 1417314 1418481 1 1417314 1418481 1417737 1418390 YPT72 IPF19068.2|IPF12899.1|Contig4-2561_0005|orf6.5901|CA3593|CaO19.2245|YPT7|YPT71 Vacuolar Rab small monomeric GTPase involved in vacuolar biogenesis; involved in filamentous growth and virulence [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1418444 1419337 - orf19.2246 1418444 1419337 1 1419337 1418444 1419303 1418533 orf19.9786|IPF25072.1|IPF12900.2|Contig4-2561_0008|orf6.5900|CA3592|CaO19.9786|CaO19.2246|IPF12900 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1419523 1421182 - orf19.2247 1419523 1421182 1 1421182 1419523 1421082 1419556 orf19.9787|IPF25051.1|IPF12902.2|Contig4-2561_0011|orf6.5899|CA3591|AQR4|CaO19.2247|CaO19.9787|IFT2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1422333 1424494 - orf19.2248 1422333 1424494 1 1424494 1422333 1424342 1422513 ARE2 orf19.9788|IPF10109.2|IPF10110.1|Contig4-2290_0009|orf6.5898|CA3590|CaO19.9788|CaO19.2248 Acyl CoA:sterol acyltransferase (ASAT); uses cholesterol and oleoyl-CoA substrates; protoberberine derivative drug inhibits enzyme activity; 7 putative transmembrane regions; ketoconazole-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1425716 1426270 + ntar_427 1425716 1426270 1 1425716 1426270 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1426268 1427184 - orf19.2249 1426268 1427184 1 1427184 1426268 1427146 1426430 orf19.9789|IPF25071.1|IPF10113.1|Contig4-2290_0005|orf6.5897|CA3589|CaO19.2249|CaO19.9789|IPF10113 Predicted ORF in Assemblies 19, 20 and 21; decreased expression observed in an ssr1 homozygous null mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1427521 1427693 - ntar_428 1427521 1427693 1 1427693 1427521 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1427894 1428894 + orf19.2250 1427894 1428894 1 1427894 1428894 1427916 1428809 SPE3 orf19.9790|IPF25063.1|IPF10115.1|Contig4-2104_0003|Contig4-2104_0004|orf6.5896|CA3588|CaO19.9790|CaO19.2250 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1429245 1430669 + orf19.2251 1429245 1430669 1 1429245 1430669 1429343 1430413 AAH1 orf19.9791|IPF25061.1|IPF10117.2|Contig4-2104_0002|orf6.5895|orf6.307|CA3587|CaO19.2251 Protein not essential for viability; similar to S. cerevisiae Aah1p, which is an adenine deaminase involved in purine salvage and nitrogen catabolism; shows colony morphology-related gene regulation by Ssn6p; Hog1p-, biofilm-, CO2-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1431742 1433280 + orf19.2252 1431742 1433280 1 1431742 1433280 1431742 1433280 orf19.9792|IPF10120.2|IPF15939.1|Contig4-2665_0008|orf6.306|orf6.5894|CA3586|AQR2|CaO19.2252|IFT3 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1434439 1436393 + orf19.2253 1434439 1436393 1 1434439 1436393 1434609 1436165 orf19.9793|IPF25047.1|IPF16720.2|Contig4-2665_0006|orf6.5893|CA3585|CaO19.9793|AQR3|CaO19.2253|IFT1 Predicted ORF in Assemblies 19, 20 and 21; expression is regulated upon white-opaque switching; transcription is repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1436527 1437412 + orf19.2256 1436527 1437412 1 1436527 1437412 1436602 1437294 orf19.9796|IPF25074.1|IPF15468.1|Contig4-2665_0004|orf6.5890|CA3584|CaO19.2256|CaO19.9796|IPF15468 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1437525 1438858 + orf19.2257 1437525 1438858 2 1437525|1437643 1437574|1438858 1437525 1438696 orf19.9797|IPF25062.1|IPF20137.1|Contig4-2665_0002|orf6.5889|CA3583|IPF20137 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1438715 1440038 - orf19.2258 1438715 1440038 1 1440038 1438715 1440036 1438852 orf19.9798|IPF25059.1|IPF15466.2|Contig4-2665_0001|orf6.5888|CA3582|CaO19.9798|CaO19.2258|IPF15466 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1440120 1441126 - orf19.2259 1440120 1441126 1 1441126 1440120 1441079 1440264 orf19.9799|IPF25066.1|IPF16143.2|Contig4-2843_0021|orf6.5887|CA3581|CaO19.9799|CaO19.2259|IPF16143 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1441244 1442493 + orf19.2260 1441244 1442493 1 1441244 1442493 1441294 1442382 orf19.9800|IPF25060.1|IPF16141.2|Contig4-2843_0020|orf6.5886|CA3580|CaO19.2260|CaO19.9800|IPF16141 Putative transcription factor with zinc finger DNA-binding motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1442729 1443813 + orf19.2261 1442729 1443813 1 1442729 1443813 1442849 1443628 orf19.9801|IPF25070.1|IPF11104.2|Contig4-2843_0018|orf6.5885|CA3579|CaO19.9801|SAP49|CaO19.2261|HSH49 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1443868 1445064 + orf19.2262 1443868 1445064 1 1443868 1445064 1443868 1445022 orf19.9802|IPF25057.1|IPF11105.2|Contig4-2843_0016|orf6.5884|CA3578|ZTA1|CaO19.2262|CaO19.9802|IPF11105 Predicted ORF in Assemblies 19, 20 and 21; similar to quinone oxidoreductases; increased transcription is observed upon benomyl treatment; induced by nitric oxide; oxidative stress-induced via Cap1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr2 1444949 1445650 - orf19.2263 1444949 1445650 1 1445650 1444949 1445592 1445053 orf19.9803|IPF25078.1|IPF11106.2|Contig4-2843_0015|orf6.5883|CA3577|CaO19.9803|CaO19.2263|IPF11106 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1445813 1447522 - orf19.2264 1445813 1447522 1 1447522 1445813 1447461 1445881 OLE2 orf19.9804|IPF25050.1|IPF11107.2|Contig4-2843_0012|orf6.5882|CA3576|CaO19.2264|CaO19.9804|IPF11107 Protein with similarity to fatty acid desaturase (stearoyl-CoA desaturase); homozygous null mutant shows decreased production of prostaglandin E2 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1447733 1449304 + orf19.2265 1447733 1449304 1 1447733 1449304 1447816 1449225 orf19.9805|IPF25054.1|IPF11108.2|Contig4-2843_0011|orf6.5881|CA3575|CaO19.9805|SNF12|CaO19.2265|IPF11108 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1449267 1452371 - orf19.2266 1449267 1452371 1 1452371 1449267 1451856 1449364 orf19.9806|IPF19585.2|IPF19584.1|Contig4-2843_0009|orf6.436|orf6.5880|CA3574|CaO19.2266|IPF19584 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1452359 1453480 + orf19.2267 1452359 1453480 1 1452359 1453480 1452518 1453336 RFA2 orf19.9807|IPF19276.2|IPF13308.1|Contig4-2843_0008|orf6.435|orf6.5879|CA3573|CaO19.2267 Protein described as DNA replication factor A; RNA abundance regulated by cell cycle, tyrosol and cell density [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1453580 1456061 - orf19.2268 1453580 1456061 1 1456061 1453580 1455586 1453817 RCK2 orf19.9808|IPF19933.1|IPF29154.1|Contig4-2843_0002|Contig4-2843_0005|orf6.3573|CA1881|CaO19.2268|CA3572|IPF18321|IPF18321.1 Predicted MAP kinase-activated protein kinase, similar to S. cerevisiae serine/threonine protein kinase Rck2p; induced by osmotic stress via Hog1p; macrophage/pseudohyphal-repressed; mutants are sensitive to rapamycin [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1457791 1458762 + orf19.2269 1457791 1458762 1 1457791 1458762 1457877 1458614 orf19.9809|IPF25073.1|IPF13316.2|Contig4-1520_0002|orf6.3572|CA1880|CaO19.2269|CaO19.9809|IPF13316 Putative 3-phosphoserine phosphatase; fungal-specific (no human or murine homolog); increased transcription is observed upon benomyl treatment or in an azole-resistant strain that overexpresses MDR1 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1459808 1461938 + orf19.2270 1459808 1461938 1 1459808 1461938 1460029 1461783 SMF12 orf19.9810|SMF1|IPF25043.1|IPF19747.1|orf6.3571|CA1879|SMF11|CaO19.2270|CaO19.9810 Protein not essential for viability; similar to S. cerevisiae Smf1p, which is a manganese transporter; Gcn4p-regulated; alkaline upregulated; caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1461961 1464974 - orf19.2272 1461961 1464974 1 1464974 1461961 1464540 1462144 orf19.9812|IPF25037.1|IPF10298.2|Contig4-2395_0001|Contig4-3049_0034|orf6.3569|CA1878|CaO19.9812|CaO19.2272|IPF10298 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1465810 1466280 - ntar_429 1465810 1466280 1 1466280 1465810 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1466424 1467253 + orf19.2274 1466424 1467253 1 1466424 1467253 1466424 1467170 orf19.9814|IPF25067.1|IPF10300.1|Contig4-3049_0033|orf6.3567|CA1877|CaO19.2274|CaO19.9814|IPF10300 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr2 1467224 1467961 - orf19.2275 1467224 1467961 1 1467961 1467224 1467917 1467393 orf19.9815|IPF25079.1|IPF10301.1|Contig4-3049_0031|orf6.3566|CA1876|CaO19.9815|MRPL12|CaO19.2275|IPF10301 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1468381 1469099 + orf19.2276 1468381 1469099 1 1468381 1469099 1468475 1468813 orf19.9816|IPF25086.1|IPF10302.1|Contig4-3049_0028|orf6.3565|CA1875|CaO19.2276|RPB9|CaO19.9816 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1468962 1471046 - orf19.2277 1468962 1471046 1 1471046 1468962 1470574 1469240 TPK2 orf19.9817|IPF25055.1|IPF10304.1|Contig4-3049_0025|Contig4-3049_0027|orf6.3564|CA1874|CaO19.2277|CaO19.9817 Catalytic subunit of cAMP-dependent protein kinase (PKA), isoform of Tpk1p; required for wild-type epithelial cell damage and engulfment and oral (not systemic) virulence in mouse; involved in control of morphogenesis and stress response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1472318 1473350 + orf19.2278 1472318 1473350 1 1472318 1473350 1472371 1473165 orf19.9818|IPF25068.1|IPF10309.2|Contig4-3049_0021|orf6.3563|orf6.997|CA0256|CaO19.2278|IPF10309 Predicted ORF in Assemblies 19, 20 and 21; filament induced; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1473290 1476239 - orf19.2280 1473290 1476239 1 1476239 1473290 1476115 1473350 ZCF10|orf19.9820|IPF25032.1|IPF10084.3|Contig4-3049_0020|orf6.2248|orf6.999|CA0257|CaO19.2280|QUA1|IPF10079|IPF10084.2 Putative transcription factor with zinc cluster DNA-binding motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 1476933 1478435 - orf19.2281 1476933 1478435 1 1478435 1476933 1478435 1476933 orf19.9821|IPF25052.1|IPF10077.2|Contig4-3049_0014|orf6.2249|CA0994|OCA99|CaO19.9821|CaO19.2281|IPF10077 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr2 1477074 1477303 + ntar_430 1477074 1477303 1 1477074 1477303 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1479147 1480139 - orf19.2282 1479147 1480139 1 1480139 1479147 1480139 1479147 orf19.9822|IPF10074.1|IPF18758.2|Contig4-3049_0013|orf6.2250|CA1112|HQD1|CaO19.2282|IPF18758|CA0995|IPF10074|IPF18758.5eoc|IPF18758.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr2 1480399 1481121 - orf19.2283 1480399 1481121 1 1481121 1480399 1481049 1480609 DQD1 orf19.9823|IPF10071.2|IPF29159.1|Contig4-3049_0012|orf6.2251|orf6.2443|CA0996|CaO19.2283|DQD99|IPF10071 Predicted ORF in Assemblies 19, 20 and 21; ketoconazole-repressed; macrophage-downregulated protein abundance [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1481279 1482571 + orf19.2284 1481279 1482571 1 1481279 1482571 1481535 1482554 orf19.9824|IPF9998.2|IPF29157.1|Contig4-3049_0010|orf6.2252|orf6.2444|CA0997|CaO19.2284|IPF9998 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1482795 1484489 + orf19.2285 1482795 1484489 1 1482795 1484489 1482795 1484489 orf19.9825|IPF18802.2|IPF9996.2|IPF9996|Contig4-3049_0008|orf6.2253|orf6.2445|CA1113|CaO19.2285 Increased transcription is observed upon benomyl treatment [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1484678 1485766 + orf19.2286 1484678 1485766 1 1484678 1485766 1484709 1485665 orf19.9826|IPF25064.1|IPF9995.2|Contig4-3049_0005|orf6.2446|CA1114|CaO19.2286|CaO19.9826|IPF9995 Predicted ORF in Assemblies 19, 20 and 21; ketoconazole-induced; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1485576 1486270 - orf19.2287 1485576 1486270 1 1486270 1485576 1486119 1485748 RPA12 orf19.9827|IPF25090.1|IPF9993.2|Contig4-3049_0004|orf6.2447|CA1115|CaO19.9827|CaO19.2287 Protein described as DNA-directed RNA polymerase I; induced upon adherence to polystyrene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1486708 1488488 + orf19.2288 1486708 1488488 1 1486708 1488488 1486767 1488413 CCT5 orf19.9828|IPF25045.1|IPF9991.2|Contig4-3049_0003|orf6.2448|CA1116|CaO19.9828|CaO19.2288 Predicted ORF in Assemblies 19, 20 and 21. Protein detected by mass spec in exponential and stationary phase cultures. [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1488664 1490121 + orf19.2289 1488664 1490121 1 1488664 1490121 1488790 1490049 ARP3 orf19.9829|IPF25056.1|IPF9988.2|Contig4-3049_0002|orf6.2449|CA1117|CaO19.9829|CaO19.2289 Predicted ORF in Assemblies 19, 20 and 21; shows Myo5p-dependent localization to cortical actin patches at hyphal tip; mutation confers hypersensitivity to cytochalasin D [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1490220 1497830 + orf19.2290 1490220 1497830 1 1490220 1497830 1490298 1497746 TOR1 orf19.9459|orf19.9461|orf19.9830|TOR|IPF25458.1|IPF9719.2|IPF25075.1|IPF9987.3|Contig4-3049_0001|orf6.7015|orf6.7017|orf6.2450|CA4469|CA4468|CA1118|orf19.1905|orf19.1903|TOR2|CaO19.9830|CaO19.2290|IPF9987|IPF9987.2 Protein similar to TOR family phosphatidylinositol kinases; mutation confers resistance to rapamycin; involved in regulation of ribosome biogenesis, starvation response, and adhesion [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1497536 1498402 - ntar_431 1497536 1498402 1 1498402 1497536 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1498568 1500426 + orf19.1902 1498568 1500426 1 1498568 1500426 1498605 1500293 NOC4 orf19.9458|IPF25429.1|IPF9717.2|Contig4-2752_0016|orf6.7018|CA4470|CaO19.1902|CaO19.9458|IPF9717 Predicted ORF in Assemblies 19, 20 and 21; mutation confers resistance to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1500527 1503368 + orf19.1901 1500527 1503368 1 1500527 1503368 1500642 1503278 MCM3 orf19.9457|IPF25419.1|IPF9716.2|Contig4-2752_0015|orf6.7019|CA4471|CaO19.9457|CaO19.1901 Predicted ORF in Assemblies 19, 20 and 21; periodic mRNA expression, peak at cell-cycle M/G1 phase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1503512 1505015 + orf19.1900 1503512 1505015 1 1503512 1505015 1503549 1505000 orf19.9456|IPF25434.1|IPF6444.2|Contig4-2752_0013|orf6.7020|CA4472|CaO19.9456|TGS1|CaO19.1900|IPF6444 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1505184 1506687 + orf19.1897 1505184 1506687 1 1505184 1506687 1505373 1506407 orf19.9453|IPF25441.1|IPF6447.1|Contig4-2752_0011|orf6.7023|CA4473|CaO19.1897|CaO19.9453|IPF6447 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1506924 1509168 + orf19.1896 1506924 1509168 1 1506924 1509168 1506984 1508930 SSC1 orf19.9452|IPF25425.1|IPF6450.2|Contig4-2752_0006|Contig4-2752_0008|orf6.7024|CA4474|CaO19.9452|CaO19.1896 Heat shock protein; at surface of yeast-form cells, but not hyphae; antigenic; soluble in hyphae; Gcn4p-regulated; induced upon amino acid starvation (3-aminotriazole) or upon adherence to polystyrene; macrophage-downregulated protein [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1509123 1511663 - orf19.1893 1509123 1511663 1 1511663 1509123 1511607 1509238 orf19.9449|IPF25421.1|IPF6455.2|Contig4-2189_0003|Contig4-2752_0004|Contig4-2752_0005|orf6.7027|CA4475|CaO19.9449|CaO19.1893|IPF6455 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1511949 1513510 - orf19.1891 1511949 1513510 1 1513510 1511949 1513476 1512217 1-Apr orf19.9447|orf6.7029|PRA|IPF25433.1|IPF6456.2|Contig4-2189_0002|CA4476|PEP4|CaO19.9447|CaO19.1891 Vacuolar aspartic proteinase; mRNA abundance is equivalent in yeast-form and mycelial cells but is elevated at lower growth temperatures; upregulated in the presence of human neutrophils; detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1514612 1516368 + orf19.1890 1514612 1516368 1 1514612 1516368 1514712 1516178 orf19.9446|IPF25432.1|IPF6459.1|orf6.7030|CA4477|CaO19.1890|CaO19.9446|IPF6459 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1516487 1518153 + orf19.1889 1516487 1518153 1 1516487 1518153 1516534 1517256 orf19.9445|IPF25444.1|IPF6461.2|orf6.7031|CA4478|CaO19.9445|CaO19.1889|IPF6461 Predicted ORF in Assemblies 19, 20 and 21; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1517186 1518429 - orf19.1888 1517186 1518429 1 1518429 1517186 1518360 1517368 orf19.9444|IPF25442.1|IPF6462.1|Contig4-2743_0009|orf6.7032|CA4479|CaO19.1888|URH1|CaO19.9444 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1519006 1521165 - orf19.1887 1519006 1521165 1 1521165 1519006 1520960 1519257 orf19.9443|IPF25430.1|IPF6464.2|Contig4-2743_0008|orf6.7033|CA4480|CaO19.9443|CaO19.1887|IPF6464 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1521327 1522778 - orf19.1886 1521327 1522778 1 1522778 1521327 1522721 1521606 RCL1 orf19.9442|IPF25440.1|IPF9148.2|Contig4-2743_0006|orf6.190|orf6.7034|CA0027|CaO19.1886 Predicted ORF in Assemblies 19, 20 and 21; essential; downregulated during core stress response; S. cerevisiae ortholog is essential [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1523032 1523225 - ntar_432 1523032 1523225 1 1523225 1523032 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1523327 1524541 + orf19.1885 1523327 1524541 1 1523327 1524541 1523380 1524471 TAF4 orf19.9441|IPF9150.1|IPF29273.1|Contig4-2743_0004|orf6.7035|CA4481|CaO19.1885|IPF9150 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to toxic ergosterol analog [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1524685 1528364 + orf19.1883 1524685 1528364 1 1524685 1528364 1524754 1528272 YCS4 orf19.9439|IPF25461.1|IPF9154.2|Contig4-2743_0002|orf6.7037|CA4482|CaO19.9439|CaO19.1883|IPF9154 Predicted ORF in Assemblies 19, 20 and 21; cell-cycle regulated periodic mRNA expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1528438 1530759 + orf19.1881 1528438 1530759 1 1528438 1530759 1528522 1530330 orf19.9437|IPF25428.1|IPF9156.2|orf6.7039|CA4483|CaO19.9437|CaO19.1881|IPF9156 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1530847 1532335 + orf19.1880 1530847 1532335 1 1530847 1532335 1531048 1532208 HEM15 orf19.9436|orf6.7040|IPF25439.1|IPF9158.2|Contig4-3010_0023|Contig4-3010_0024|CA4484|CaO19.1880|CaO19.9436 Putative ferrochelatase involved in heme biosynthesis; transcription is not regulated by iron levels and is also not affected by a yfh1 null mutation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1532191 1533427 - orf19.1878 1532191 1533427 1 1533427 1532191 1533274 1532303 orf19.9434|IPF25443.1|IPF9160.2|Contig4-3010_0022|orf6.7042|CA4485|CaO19.1878|CaO19.9434|IPF9160 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1533448 1534361 + orf19.1877 1533448 1534361 1 1533448 1534361 1533526 1534341 orf19.9433|IPF25445.1|IPF9162.2|Contig4-3010_0019|orf6.7043|CA4486|CaO19.1877|CaO19.9433|IPF9162 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1534226 1535819 - orf19.1876 1534226 1535819 1 1535819 1534226 1535696 1534338 orf19.9432|IPF25435.1|IPF4039.2|Contig4-3010_0018|orf6.7044|CA4487|NAM8|CaO19.9432|CaO19.1876|IPF4039 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1535827 1537231 - orf19.1874 1535827 1537231 2 1537231|1536549 1536617|1535827 1537231 1535827 orf19.9430|orf19.9431|IPF4042.2|IPF25446.1|IPF29274.1|IPF4041.1|Contig4-3010_0012|Contig4-3010_0014|Contig4-3010_0015|orf6.7045|orf6.7046|CA4489|CA4488|orf19.1875|MEK.5f [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1537831 1538460 + orf19.1873 1537831 1538460 1 1537831 1538460 1537876 1538208 orf19.9429|IPF4044.1|IPF17567.2|Contig4-3010_0011|orf6.282|orf6.7047|CaO19.1873 Predicted ORF in Assemblies 19, 20 and 21; repressed by nitric oxide; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1538659 1539580 + orf19.1872 1538659 1539580 1 1538659 1539580 1538720 1539355 orf19.9428|IPF4045.1|IPF17566.1|Contig4-3010_0010|orf6.283|orf6.7048|CA4490|CaO19.1872|IPF4045 Predicted ORF in Assemblies 19, 20 and 21; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1539834 1544891 + orf19.1871 1539834 1544891 1 1539834 1544891 1539900 1544825 orf19.9427|IPF4050.2|IPF29275.1|Contig4-3010_0009|orf6.284|orf6.7049|CA4491|SWR1|CaO19.1871 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1544803 1545121 - ntar_433 1544803 1545121 1 1545121 1544803 1545121 1544816 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1546030 1547657 + orf19.1868 1546030 1547657 1 1546030 1547657 1546130 1547314 RNR22 orf19.9424|IPF25438.1|IPF4053.1|Contig4-3010_0006|orf6.7052|CA4492|RNR2|CaO19.9424|CaO19.1868 Protein described as ribonucleoside diphosphate reductase; shows colony morphology-related gene regulation by Ssn6p; RNA abundance regulated by tyrosol and cell density [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1547722 1549012 - ntar_434 1547722 1549012 1 1549012 1547722 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1547799 1548998 + orf19.1867 1547799 1548998 1 1547799 1548998 1547799 1548998 orf19.9423|MAE1|IPF25437.1|IPF4055.2|Contig4-3010_0003|Contig4-3010_0005|orf6.7053|CA4493|CaO19.9423|SSU12|CaO19.1867|IPF4055 Putative malate permease; induced during macrophage infection; regulated by Gcn2p and Gcn4p; has putative peroxisome targeting signal [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr2 1549217 1549848 + orf19.1866 1549217 1549848 1 1549217 1549848 1549286 1549627 orf19.9422|IPF25457.1|IPF4056.2|Contig4-3010_0002|orf6.7054|CA4494|VMA10|CaO19.9422|CaO19.1866|VMA1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1549721 1551909 - orf19.1865 1549721 1551909 1 1551909 1549721 1551800 1549956 orf19.9421|IPF25426.1|IPF4059.1|Contig4-3010_0001|orf6.7055|CA4495|CaO19.9421|CaO19.1865|IPF4059 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1551994 1554467 - orf19.1864 1551994 1554467 1 1554467 1551994 1554414 1552255 orf19.9420|IPF4062.2|IPF19004.2|Contig4-3010_0027|orf6.1264|orf6.7056|CA4496|CaO19.1864|IPF4062 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1554724 1556511 + orf19.1863 1554724 1556511 1 1554724 1556511 1554724 1556511 orf19.9419|IPF4064.2|IPF19005.1|Contig4-2502_0003|orf6.1263|orf6.7057|CA4497|CaO19.1863|IPF4064.5f|IPF4064 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1556446 1557148 - orf19.1862 1556446 1557148 1 1557148 1556446 1556975 1556610 orf19.9418|IPF4065|orf6.1262|IPF18208.2|IPF4065.1|Contig4-2502_0004|CA0386|CaO19.1862 Possible stress protein; increased transcription is associated with CDR1 and CDR2 overexpression or fluphenazine treatment; transcription regulated by Sfu1p, Nrg1p, Tup1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1558217 1560347 + orf19.1861 1558217 1560347 1 1558217 1560347 1558356 1560230 orf19.9417|orf19.9763|IPF25427.1|IPF4071.2|IPF25109.1|IPF29169.1|orf6.1261|orf6.4263|CA0385|orf19.2218|CaO19.1861|CaO19.9417|IPF4071 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1560045 1561799 - orf19.1860.1 1560045 1561799 1 1561799 1560045 1561733 1560333 orf19.9762|IPF25116.1|IPF4072.2|orf6.1260|orf6.4262|CA2380|orf19.2217 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1562001 1566104 + orf19.2216 1562001 1566104 1 1562001 1566104 1562086 1565997 PDS5 orf19.9761|IPF25164.1|IPF4073.2|Contig4-1620_0001|orf6.4261|CA2379|CaO19.9761|CaO19.2216|IPF4073 Predicted ORF in Assemblies 19, 20 and 21; cell-cycle regulated periodic mRNA expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1566003 1567818 - orf19.2215 1566003 1567818 1 1567818 1566003 1567634 1566132 GLE1 orf19.9760|IPF25118.1|IPF15261.2|Contig4-1620_0004|Contig4-1620_0006|orf6.4260|CA2378|CaO19.2215|CaO19.9760 Predicted ORF in Assemblies 19, 20 and 21; moderately induced at 42 deg [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1568280 1569283 + orf19.2214 1568280 1569283 1 1568280 1569283 1568309 1569172 orf19.9759|IPF25143.1|IPF15259.2|Contig4-2359_0006|orf6.4259|CA2377|CaO19.2214|MRPL7|CaO19.9759 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1569348 1571259 + orf19.2213 1569348 1571259 1 1569348 1571259 1569408 1570772 orf19.9758|IPF25122.1|IPF15506.2|Contig4-2359_0005|orf6.4258|CA2376|CaO19.2213|CaO19.9758|IPF15506 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1570837 1571154 - orf19.2212 1570837 1571154 1 1571154 1570837 1571154 1570837 orf19.9757|IPF25170.1|IPF15505.1|Contig4-2359_0004|orf6.4257|CaO19.9757|CaO19.2212 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1571396 1572238 + orf19.2211 1571396 1572238 1 1571396 1572238 1571396 1572238 orf19.9756|IPF25144.1|IPF15504.1|Contig4-2359_0003|orf6.4256|CA2375|CaO19.2211|CaO19.9756|IPF15504 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1572187 1574465 - orf19.2210 1572187 1574465 1 1574465 1572187 1574362 1572314 orf19.9755|IPF19934.2|IPF29168.1|Contig4-2359_0002|Contig4-3058_0002|orf6.3574|orf6.4255|CA1882|CaO19.2210|IPF19934|IPF19934.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1577333 1579918 + orf19.2209 1577333 1579918 1 1577333 1579918 1577496 1579523 YVC1 orf19.9754|IPF25104.1|IPF5479.2|Contig4-3058_0005|orf6.3575|CA1883|CaO19.2209|CaO19.9754|IPF5479 Protein similar to S. cerevisiae Yvc1p; transcription is repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1580453 1585143 + orf19.2208 1580453 1585143 1 1580453 1585143 1580742 1584941 orf19.9753|IPF25161.1|IPF5486.2|Contig4-3058_0008|Contig4-3058_0011|orf6.3576|CA1884|CaO19.9753|CaO19.2208|IPF5486 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1585488 1586493 + orf19.2204.2 1585488 1586493 1 1585488 1586493 1585831 1586394 IPF25102.1|IPF5490.1|Contig4-3058_0013|CA1886|RHO2.3f ORF Predicted by Annotation Working Group (see Locus History Note for Assembly 19 correction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1586528 1586713 - ntar_435 1586528 1586713 1 1586713 1586528 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1587269 1588883 + orf19.2204 1587269 1588883 1 1587269 1588883 1587418 1588800 orf19.9749|IPF25125.1|IPF5496.1|Contig4-3058_0014|Contig4-3058_0015|Contig4-3058_0016|orf6.3580|CA1887|CaO19.2204|CaO19.9749|IPF5496 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1587271 1589344 - orf19.2203.1 1587271 1589344 1 1589344 1587271 1589275 1588979 ORF added to Assembly 21 based on comparative genome analysis; overlaps dubious orf19.2203 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1589241 1589558 + orf19.2203 1589241 1589558 1 1589241 1589558 1589241 1589558 IPF29181.1|orf6.4338|CaO19.2203 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1589495 1590404 - orf19.2202 1589495 1590404 1 1590404 1589495 1590300 1589575 orf19.9748|IPF18594.1|IPF5498.1|Contig4-3058_0019|orf6.3581|orf6.4339|CA1888|CaO19.2202|IPF18594 Predicted ORF in Assemblies 19, 20 and 21; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1591011 1591579 + orf19.2201 1591011 1591579 1 1591011 1591579 1591049 1591387 orf19.9747|IPF18593.2|IPF5499.1|Contig4-3058_0021|orf6.3582|orf6.4340|CA1889|CBP6|CaO19.9747|CaO19.2201|IPF18593.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1591783 1593333 + orf19.2200 1591783 1593333 1 1591783 1593333 1591892 1593202 orf19.9746|IPF25130.1|IPF5500.2|Contig4-3058_0024|orf6.4341|CA2436|CaO19.2200|CaO19.9746|IPF5500 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1593203 1594444 - orf19.2199 1593203 1594444 1 1594444 1593203 1594358 1593351 PHO86 orf19.9745|IPF25140.1|IPF5501.1|Contig4-3058_0025|orf6.4342|CA2437|CaO19.9745|CaO19.2199 Predicted ORF in Assemblies 19, 20 and 21; possibly adherence-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1595405 1598157 + orf19.2198 1595405 1598157 1 1595405 1598157 1595730 1597886 FLC3 orf19.9744|IPF25103.1|IPF5505.2|Contig4-3058_0030|orf6.4343|CA2438|CaO19.2198|CFP3|CaO19.9744|IPF5505 Protein involved in heme uptake; putative FAD transporter, similar to S. cerevisiae Flc3p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1598856 1600358 + orf19.2197 1598856 1600358 1 1598856 1600358 1598856 1600358 orf19.9743|IPF25119.1|IPF7514.2|Contig4-3058_0032|orf6.4344|CA2439|CaO19.2197|CaO19.9743|IPF7514 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1600445 1600516 - tm(cau)2 1600445 1600516 1 1600516 1600445 tM(CAU)2.2 tRNA-Met predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1600726 1601001 - ntar_436 1600726 1601001 1 1601001 1600726 1601001 1600834 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1600892 1602515 + orf19.2196 1600892 1602515 1 1600892 1602515 1601015 1602379 orf19.9742|IPF25128.1|IPF7513.2|Contig4-3058_0034|orf6.4345|CA2440|CaO19.2196|CUE3|CaO19.9742|IPF7513 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1601392 1601934 - orf19.2195 1601392 1601934 1 1601934 1601392 1601934 1601392 IPF25151.1|IPF7512.2|orf6.4346 ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1602543 1604088 + orf19.2194 1602543 1604088 1 1602543 1604088 1602661 1604073 orf19.9740|IPF25124.1|IPF7509.2|Contig4-3058_0036|orf6.4347|CA2441|CaO19.2194|APM4|CaO19.9740 Phosphorylated protein of unknown function; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1604322 1605862 + orf19.2193 1604322 1605862 1 1604322 1605862 1604375 1605715 PRS5 orf19.9739|IPF25123.1|IPF7507.2|Contig4-3058_0037|orf6.4348|CA2442|CaO19.9739|CaO19.2193 Predicted ORF in Assemblies 19, 20 and 21; downregulated during core stress response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1607145 1607567 + ntar_437 1607145 1607567 1 1607145 1607567 1607368 1607502 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1608078 1611798 + orf19.2192 1608078 1611798 1 1608078 1611798 1608435 1611605 GDH2 orf19.9738|IPF19745.1|IPF29185.1|Contig4-2073_0005|Contig4-2073_0006|Contig4-2075_0005|orf6.3428|CA1775|CaO19.2192 Putative NAD-specific glutamate dehydrogenase; fungal-specific (no human or murine homolog); transcription is regulated by Nrg1p, Mig1p, Tup1p, and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1611591 1612121 - orf19.2191.1 1611591 1612121 1 1612121 1611591 1612089 1611913 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1612141 1613410 + orf19.2191 1612141 1613410 1 1612141 1613410 1612254 1613291 orf19.9737|IPF25137.1|IPF7498.2|Contig4-2075_0002|orf6.3427|CA1774|CaO19.9737|CaO19.2191|IPF7498 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1613227 1615337 - orf19.2190 1613227 1615337 1 1615337 1613227 1615337 1613343 VRP1 orf19.9736|IPF25107.1|IPF12461.2|orf6.3426|CA1773|CaO19.2190|CaO19.9736 Protein described as verprolin; downregulated upon adherence to polystyrene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1615450 1617290 - orf19.2187 1615450 1617290 1 1617290 1615450 1617026 1615542 ALG7 orf19.9733|IPF25121.1|IPF12460.2|Contig4-2452_0003|orf6.3423|CA1772|CaO19.2187|CaO19.9733 Protein involved in cell wall mannan biosynthesis; mutation confers hypersensitivity to tunicamycin; transcription is elevated in chk1, nik1, and sln1 homozygous null mutants [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1617552 1618731 + orf19.2186 1617552 1618731 1 1617552 1618731 1617552 1618595 orf19.9732|IPF25138.1|IPF12458.2|Contig4-2452_0004|orf6.3422|CA1771|CaO19.9732|SEH1|CaO19.2186 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr2 1618129 1619838 - orf19.2185 1618129 1619838 1 1619838 1618129 1619808 1618588 NSA1 orf19.9731|IPF25132.1|IPF12457.2|Contig4-2452_0006|orf6.3421|CA1770|CaO19.2185|CaO19.9731|IPF12457 Predicted ORF in Assemblies 19, 20 and 21; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1620320 1620406 + ti(aau)2 1620320 1620406 2 1620320|1620371 1620357|1620406 tI(AAU)2.2 tRNA-Ile predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1620484 1621590 + orf19.2184 1620484 1621590 1 1620484 1621590 1620567 1621463 orf19.9730|IPF12454.2|IPF5534.2|Contig4-2452_0008|orf6.3420|orf6.6079|CA3735|FAH2|CaO19.2184|IPF5534|IPF5534.1 Predicted ORF in Assemblies 19, 20 and 21; clade-associated gene expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1621657 1621915 + ta(agc)1 1621657 1621915 1 1621657 1621915 1621693 1621860 tA(AGC)1.2 tRNA-Ala predicted by tRNAscan-SE [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=D scenario_last_exon=D] Ca21chr2 1621783 1623771 - orf19.2183 1621783 1623771 1 1623771 1621783 1623732 1621903 KRE30 orf19.9729|IPF25112.1|IPF5533.2|Contig4-3057_0002|orf6.6080|CA3736|CaO19.2183|CaO19.9729|IPF5533 YEF3-subfamily ABC family protein, predicted not to be a transporter; downregulated during core stress response; mutation confers hypersensitivity to amphotericin B [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1624632 1631501 + orf19.2182 1624632 1631501 1 1624632 1631501 1624806 1631408 BLM3 orf19.9728|IPF25148.1|IPF5529.1|Contig4-3057_0004|Contig4-3057_0005|orf6.6081|CA3737|CaO19.2182|CaO19.9728 Predicted ORF in Assemblies 19, 20 and 21; similar to S. cerevisiae Blm10p; transcription is regulated by Nrg1p and Mig1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1631407 1633104 - orf19.2180 1631407 1633104 1 1633104 1631407 1632775 1631660 orf19.9726|IPF25136.1|IPF5526.1|Contig4-3057_0008|orf6.6083|CA3738|CaO19.9726|CaO19.2180|IPF5526 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1632310 1632840 + orf19.2181 1632310 1632840 1 1632310 1632840 1632310 1632840 IPF25147.1|IPF5525.1|orf6.6082|CaO19.2181|CaO19.9727 [NOT TRANSCRIBED?] ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1633229 1634190 - orf19.2179.2 1633229 1634190 2 1634190|1633750 1634070|1633229 1634121 1633446 RPS10 IPF25168.1|IPF5524.1|Contig4-3057_0011|Contig4-3057_0012|CA3739|RPS10.3 Predicted ribosomal protein; downregulated in the presence of human whole blood or polymorphonuclear (PMN) cells [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1634521 1636374 - orf19.2179 1634521 1636374 1 1636374 1634521 1636365 1634551 SIT1 orf19.9725|ARN1|orf6.6084|YHL040C|IPF25111.1|IPF5522.1|Contig4-3057_0013|CA3740|CaO19.2179|CaO19.9725 Transporter of ferrichrome siderophores, but not ferrioxamine B; required for wild-type invasion of human epithelial cells in vitro, but not for wild-type systemic virulence in mouse; transcription regulated by iron, Sfu1p, Rfg1p, Tup1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 1637875 1638802 + orf19.2178.1 1637875 1638802 1 1637875 1638802 1638462 1638671 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1638712 1640343 - orf19.2178 1638712 1640343 1 1640343 1638712 1639848 1638871 orf19.9724|IPF25142.1|IPF5513.1|Contig4-3057_0017|orf6.6085|CA3741|CaO19.2178|MRS3|CaO19.9724|MRS4 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1640878 1642598 - orf19.2176 1640878 1642598 1 1642598 1640878 1642014 1640977 IFM3 orf19.9722|IPF25139.1|IPF5511.1|Contig4-3057_0018|orf6.6087|CA3742|CaO19.2176|CaO19.9722 Predicted ORF in Assemblies 19, 20 and 21; Plc1p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1641445 1641981 + orf19.2177 1641445 1641981 1 1641445 1641981 1641445 1641981 IPF25150.1|IPF5510.1|orf6.6086 ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1642714 1644066 + orf19.2175 1642714 1644066 1 1642714 1644066 1642904 1644007 orf19.9721|IPF25135.1|IPF19998.1|Contig4-3057_0019|Contig4-3057_0021|Contig4-3057_0022|orf6.6088|CA3743|CPD1|CaO19.9721|CaO19.2175|IPF19998 Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1644189 1645792 + orf19.2174 1644189 1645792 1 1644189 1645792 1644238 1645773 RAD57 orf19.9720|IPF25120.1|IPF10144.2|Contig4-3057_0023|orf6.6089|CA3744|CaO19.9720|CaO19.2174 Essential protein; described as having role in DNA recombination, repair; transcriptionally induced by interaction with macrophage; transcription is regulated by Nrg1p, Mig1p, and Tup1p; S. cerevisiae ortholog is essential [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1646076 1647749 + orf19.2173 1646076 1647749 2 1646076|1646397 1646211|1647749 1646206 1647533 MAF1 orf19.9719|IPF25133.1|IPF10146.2|Contig4-3057_0024|orf6.6090|CA3745 Protein described as affecting nucleocytoplasmic transport and synthesis of RNA Polymerase III; decreased expression in hyphae compared to yeast-form cells; caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1647969 1649352 + orf19.2172 1647969 1649352 1 1647969 1649352 1648100 1649080 ARA1 orf19.9718|IPF25141.1|IPF10148.2|Contig4-3057_0027|orf6.6091|CA3746|CaO19.9718|CaO19.2172 D-Arabinose dehydrogenase; in dehydro-D-arabinono-1,4-lactone biosynthesis; NADP+ cofactor; active toward D-arabinose, L-fucose, L-xylose, L-galactose; inhibited by metal ions, thiol group-specific reagents; induced on polystyrene adherence [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1649270 1652438 - orf19.2170 1649270 1652438 1 1652438 1649270 1652255 1649472 PHM7 orf19.9716|IPF25099.1|IPF10153.2|Contig4-3057_0029|orf6.6093|CA3747|CaO19.2170|IPF10153 Putative transporter; fungal-specific (no human or murine homolog); Hog1p-downregulated; downregulated in response to 17-beta-estradiol, ethynyl estradiol [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1654307 1655002 + orf19.2169 1654307 1655002 1 1654307 1655002 1654307 1655002 orf19.9715|IPF16181.3|IPF29176.1|orf6.1806|orf6.6094|CA6200|CaO19.2169|IPF29176 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1655000 1655889 - orf19.2168.3 1655000 1655889 2 1655889|1655618 1655776|1655000 1655826 1655148 IPF13710.3|IPF16182.1|Contig4-2572_0016|CA6199|IPF16182 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1656164 1656976 + ntar_438 1656164 1656976 1 1656164 1656976 1656355 1656555 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1657091 1658434 + orf19.2168 1657091 1658434 1 1657091 1658434 1657091 1658434 orf19.9714|IPF25127.1|IPF13715.1|Contig4-2572_0010|orf6.1805|CA0713|CaO19.9714|AES2|CaO19.2168|IFJ2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr2 1658481 1660192 - orf19.2167 1658481 1660192 2 1660192|1660034 1660118|1658481 1660135 1658682 orf19.9713|IPF25129.1|IPF13717.1|Contig4-2572_0007|orf6.1804|CA0712|CaO19.9713|CaO19.2167|IPF13717 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1660573 1662192 + orf19.2166 1660573 1662192 1 1660573 1662192 1660762 1661928 orf19.9712|IPF13718.3|IPF29174.1|Contig4-2572_0004|orf6.1314|orf6.1803|CA0711|VMA5|CaO19.2166|IPF13718.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1662341 1663624 + orf19.2165 1662341 1663624 1 1662341 1663624 1662652 1663488 orf19.9711|IPF16630.3|IPF25145.1|IPF29175.1|Contig4-2572_0003|orf6.754|orf6.1313|CA6233|CA6198|orf19.1125|CaO19.9711|HWH3|CaO19.2165|IPF29175 Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1663802 1663930 - orf19.2164.1 1663802 1663930 1 1663930 1663802 1663930 1663802 MFA1 Mating pheromone, a-factor; produced in opaque MTLa cells; required for mating competence of MTLa cells, but not MTLalpha; induced by alpha-factor [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1665815 1669441 + orf19.2219 1665815 1669441 1 1665815 1669441 1665815 1669441 ORF298 orf19.9710|orf19.9764|IPF25169.1|IPF4068.2|IPF25165.1|IPF29182.1|Contig4-2502_0009|Contig4-2502_0010|orf6.1312|orf6.4264|POL|CA0414|orf19.2164|POL94|CaO19.9764|CaO19.2219 Predicted ORF in retrotransposon Tca3 with similarity to Gag-Pol, which encodes nucleocapsid-like protein, reverse transcriptase, protease, and integrase; transcription is a-specific, alpha-factor induced; mRNA binds to She3p [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1670638 1670949 + orf19.2220 1670638 1670949 1 1670638 1670949 1670638 1670949 orf19.9765|IPF25157.1|IPF11641.1|orf6.4265|CaO19.2220|CaO19.9765 Predicted ORF in Assemblies 19, 20 and 21; induced by Rgt1p [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1671059 1673062 - orf19.2222 1671059 1673062 1 1673062 1671059 1672713 1671577 orf19.9766|orf19.9767|YCK3|IPF25134.1|IPF11643.2|Contig4-2626_0009|orf6.4266|orf6.4267|CA2381|CA2382|orf19.2221|YCK22|CaO19.2222|CaO19.9767|YCK3.5f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1673269 1674806 + orf19.2660 1673269 1674806 1 1673269 1674806 1673425 1674534 EAF3 IPF11644|IPF18475.1|IPF11644.3|Contig4-2626_0007|orf6.1465|CA0496|orf19.2222.1|ALP13|CaO19.2660|IPF11644.2 Subunit of the NuA4 histone acetyltransferase complex [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1675679 1676610 - orf19.1354 1675679 1676610 1 1676610 1675679 1676610 1676005 UCF1 orf19.8934|orf6.1218|IPF20056|IPF20056.1|IPF20057.1|Contig4-1837_0007|Contig4-2626_0005|orf6.1464|YER67|CA0495|orf19.2659|CaO19.8934|CaO19.1354 Putative protein of unknown function; mRNA binds to She3p; transcription is induced in high iron, decreased upon yeast-hyphal switch; downregulation correlates with clinical development of fluconazole resistance; Ras1p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1676646 1677182 - orf19.1353 1676646 1677182 1 1677182 1676646 1677182 1676646 orf19.8933|IPF25986.1|IPF11646.2|Contig4-1837_0006|Contig4-2626_0004|orf6.1217|CA0368|CaO19.8933|CaO19.1353|IPF11646 Predicted ORF in Assemblies 19, 20 and 21; transcription downregulated upon yeast-hyphal switch; Ras1p-regulated [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1678087 1679225 + orf19.1352 1678087 1679225 1 1678087 1679225 1678514 1679068 orf19.8932|IPF25985.1|IPF16416.2|IPF18964.1|Contig4-1837_0001|orf6.1216|orf6.1463|CA0367|orf19.2658|CaO19.8932|TIM22|CaO19.1352 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1679118 1680025 - orf19.1351 1679118 1680025 1 1680025 1679118 1679940 1679200 orf19.8931|IPF19017.1|IPF19081.2|orf6.1215|orf6.978|CA0366|CaO19.1351|IPF19017 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1681554 1682898 + orf19.1350 1681554 1682898 1 1681554 1682898 1681722 1682720 orf19.8930|IPF19616.2|IPF19617.1|Contig4-3000_0026|orf6.1214|orf6.979|CA0249|CaO19.1350|IPF19617 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1683047 1683487 - orf19.1349 1683047 1683487 1 1683487 1683047 1683487 1683047 orf19.8929|IPF25987.1|IPF9726.2|Contig4-3000_0024|Contig4-3000_0025|orf6.980|CaO19.1349|CaO19.8929 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1684575 1685138 - orf19.1348 1684575 1685138 1 1685138 1684575 1685138 1684575 orf19.12588|orf19.8928|IPF25984.1|IPF17661.1|IPF22162.1|IPF9727.2|Contig4-3000_0022|orf6.981|orf6.6328|CA0250|orf19.5122|CaO19.8928|CaO19.1348|IPF17661 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1685648 1688413 - orf19.5121 1685648 1688413 1 1688413 1685648 1688413 1685648 OPT5 orf19.12587|orf19.8927|IPF17662.1|IPF22113.1|IPF9728.2|Contig4-3000_0021|orf6.982|CA3919|orf19.1347|CaO19.5121|OPT251|CaO19.12587|IFC5|orf6.6329 [NOT TRANSCRIBED?] Oligopeptide transporter; fungal-specific (no human or murine homolog); induced by BSA, but not by tetrapeptide or pentapeptide [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1690361 1692149 - orf19.1435 1690361 1692149 1 1692149 1690361 1691935 1690559 TEF1 orf19.12585|orf19.9009|TEF-1|TEF3|YEF3|EFT3|IPF9732.2|IPF29461.1|IPF22137.1|IPF28153.1|HEF1|Contig4-2267_0001|orf6.1202|orf6.6331|CA0362|orf19.5119|TEF2-2|CaO19.1435|CaO19.9009 Translation elongation factor 1-alpha, detected at surface of yeast-form and hyphal cells; binds human plasminogen; macrophage/pseudohyphal-induced; upregulated in an RHE model of oral candidiasis and in clinical oral candidiasis isolates [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 1692262 1694598 - orf19.1434 1692262 1694598 1 1694598 1692262 1694489 1692342 orf19.9008|IPF9733.2|IPF17695.2|Contig4-2267_0004|orf6.1038|orf6.1203|CA0272|CaO19.1434|DPB11 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1692326 1692611 + ntar_439 1692326 1692611 1 1692326 1692611 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1694871 1696793 + orf19.1433 1694871 1696793 1 1694871 1696793 1695466 1696659 orf19.9007|IPF25891.1|IPF19066.1|orf6.1039|CA0273|CaO19.9007|CaO19.1433|IPF19066 Predicted ORF in Assemblies 19, 20 and 21; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1696732 1696851 - orf19.1433.1 1696732 1696851 1 1696851 1696732 [NOT TRANSCRIBED?] ORF added to Assembly 21 based on comparative genome analysis; overlaps orf19.1433.2, which is annotated as a blocked reading frame [label_first_exon=CGD label_last_exon=CGD orf_changed=true scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1697454 1697662 - ntar_440 1697454 1697662 1 1697662 1697454 1697604 1697479 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1699165 1700553 + orf19.3639 1699165 1700553 1 1699165 1700553 1699324 1700388 orf19.11121|IPF23673.1|IPF14127.2|Contig4-2385_0005|orf6.2754|CA1314|CaO19.3639|MAG1|CaO19.11121 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1700457 1701479 - orf19.3638 1700457 1701479 1 1701479 1700457 1701479 1700457 PGA46 orf19.11120|IPF18709.2|IPF14126.2|Contig4-2385_0004|orf6.2753|CA1313|CaO19.11120|CaO19.3638|IPF14126 Putative GPI-anchored protein of unknown function [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1701552 1701869 + orf19.3637 1701552 1701869 1 1701552 1701869 1701552 1701869 orf19.11119|IPF23692.1|IPF28717.1|orf6.2752|CaO19.11119|CaO19.3637 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1704786 1709600 + orf19.3635 1704786 1709600 1 1704786 1709600 1704794 1709485 orf19.11117|IPF14241.2|IPF28710.1|Contig4-2417_0002|orf6.2750|CA1312|CaO19.11117|CaO19.3635|IPF14241 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 1709624 1710307 - orf19.3633 1709624 1710307 1 1710307 1709624 1710179 1709691 orf19.11115|IPF23682.1|IPF14233.1|Contig4-2417_0003|orf6.2748|CA1311|CaO19.11115|CaO19.3633|IPF14233 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1710483 1712384 - orf19.3631 1710483 1712384 1 1712384 1710483 1712272 1710509 orf19.11114|IPF14232.2|IPF28707.1|Contig4-2417_0005|orf6.2708|orf6.2747|CA1310|CaO19.3631|IPF14232|IPF14232.1 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 1712583 1714244 + orf19.3630 1712583 1714244 1 1712583 1714244 1712650 1713936 RRP8 orf19.11113|IPF23665.1|IPF10837.2|orf6.2709|CA1277|CaO19.11113|CaO19.3630|IPF10837 Predicted ORF in Assemblies 19, 20 and 21; induced upon biofilm formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1714095 1714290 - ntar_441 1714095 1714290 1 1714290 1714095 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1714464 1714875 - ntar_442 1714464 1714875 1 1714875 1714464 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1715579 1718513 + orf19.3629 1715579 1718513 1 1715579 1718513 1716138 1718312 DSE1 orf19.11112|IPF23656.1|IPF10835.2|Contig4-2517_0008|Contig4-2517_0009|orf6.2710|CA1278|CaO19.3629|CaO19.11112|IPF10835 Predicted cell wall protein; transcription is decreased in mutant lacking ACE2; periodic mRNA expression, peak at cell-cycle M/G1 phase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1718765 1719050 + ntar_443 1718765 1719050 1 1718765 1719050 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1718916 1719287 - ntar_444 1718916 1719287 1 1719287 1718916 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1719439 1722309 + orf19.3628 1719439 1722309 1 1719439 1722309 1719503 1722001 RSP5 orf19.11111|IPF23654.1|IPF10833.2|Contig4-2517_0005|Contig4-2517_0007|orf6.2711|CA1279|CaO19.3628|CaO19.11111 Predicted ORF in Assemblies 19, 20 and 21; induced during infection of murine kidney, compared to growth in vitro; has murine homolog [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1722615 1723577 + orf19.3627 1722615 1723577 1 1722615 1723577 1722702 1723421 orf19.11110|IPF18958.2|IPF10828.2|Contig4-2517_0004|orf6.1478|orf6.2712|CA1280|CaO19.3627|IPF10828 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1723640 1723825 - orf19.3626.1 1723640 1723825 1 1723825 1723640 1723801 1723640 IPF18957.1|CA0505|IPF11988.3f|IPF11988.3 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1724312 1726526 - orf19.3626 1724312 1726526 1 1726526 1724312 1726526 1724412 orf19.11109|IPF23662.1|IPF18957.1|IPF11988.2|IPF28722.1|Contig4-1622_0003|Contig4-3078_0001|orf6.1479|CA0506|IPF11988.5f|IPF11988 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1726577 1727832 - orf19.3625 1726577 1727832 1 1727832 1726577 1727787 1726738 orf19.11108|IPF23675.1|IPF11989.2|Contig4-2568_0007|orf6.1480|CA0507|YNG1|CaO19.11108|CaO19.3625|IPF11989 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1728276 1731843 - orf19.3624 1728276 1731843 1 1731843 1728276 1731843 1728403 orf19.11107|IPF11991.3|IPF28720.1|Contig4-2568_0003|orf6.1481|orf6.1516|CA0508|CaO19.3624|MSU1|IPF11991|IPF11991.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr2 1732041 1735889 + orf19.3623 1732041 1735889 1 1732041 1735889 1732194 1735709 SMC2 orf19.11106|IPF23694.1|IPF11993.2|Contig4-2568_0001|orf6.1515|CA0529|CaO19.3623 Protein similar to S. cerevisiae Smc2p, which is a component of the condensin complex involved in mitotic chromosome condensation; induced under hydroxyurea treatment [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1736379 1738349 + orf19.3622 1736379 1738349 1 1736379 1738349 1736880 1738166 ANP1 orf19.11105|IPF23669.1|IPF5178.2|Contig4-1830_0001|orf6.1514|CA0528|CaO19.3622|CaO19.11105 Putative mannosyltransferase of Golgi; member of Mnn9p family; similar to S. cerevisiae Anp1p; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1739765 1741000 + orf19.3621 1739765 1741000 1 1739765 1741000 1739765 1741000 orf19.11104|IPF23670.1|IPF5180.3|Contig4-1595_0002|orf6.1513|orf6.3291|CA0527|CaO19.3621|IPF5180|CA1679|IPF5180.3eoc|IPF18631.1 Possible pseudogene; similar to Ywp1p; ORF extended upstream from the initiating Met of orf19.3621 has a stop codon in the region corresponding to the Ywp1p signal peptide; disruption causes no apparent phenotype; no expression detected [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr2 1740775 1741328 - ntar_445 1740775 1741328 1 1741328 1740775 1741328 1741170 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1741432 1742055 - ntar_446 1741432 1742055 1 1742055 1741432 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1741580 1742054 + ntar_447 1741580 1742054 1 1741580 1742054 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1743701 1743930 - ntar_448 1743701 1743930 1 1743930 1743701 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1744348 1744713 - ntar_449 1744348 1744713 1 1744713 1744348 1744511 1744368 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1744371 1745250 + ntar_450 1744371 1745250 1 1744371 1745250 1744531 1744677 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1744912 1745273 - ntar_451 1744912 1745273 1 1745273 1744912 1745161 1745030 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1745465 1745745 - ntar_452 1745465 1745745 1 1745745 1745465 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1746941 1749161 + orf19.3618 1746941 1749161 1 1746941 1749161 1747033 1748634 YWP1 orf19.11101|orf6.3288|FLO1|TEP1|IPF5185|CA1678|PGA24|IPF23664.1|IPF5185.2|Contig4-2227_0007|CaO19.3618|CaO19.11101 Cell wall and secreted protein with suggested role in dispersal in host; mutation causes increased adhesion and biofilm formation; has stable propeptide; regulated by growth phase, phosphate, Ssk1p, Ssn6p, Efg1p, Efh1p; mRNA binds to She3p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1749527 1749775 + ntar_453 1749527 1749775 1 1749527 1749775 1749527 1749775 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1750041 1751479 + orf19.3617 1750041 1751479 1 1750041 1751479 1750180 1751238 orf19.11100|IPF23676.1|IPF5189.2|Contig4-2008_0006|Contig4-2227_0011|orf6.3287|CA1677|CaO19.3617|GTR1|CaO19.11100 Putative protein of unknown function, transcription is upregulated in clinical isolates from HIV+ patients with oral candidiasis;; predicted ORF in Assemblies 19, 20 and 21 (see Locus History Note for Assembly 19 correction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1750851 1751489 - ntar_454 1750851 1751489 1 1751489 1750851 1751291 1751157 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1751751 1753626 + orf19.3616 1751751 1753626 1 1751751 1753626 1752011 1753357 ERG9 orf19.11099|IPF23667.1|IPF5191.2|Contig4-2008_0002|orf6.3286|CA1676|CaO19.3616|CaO19.11099 Putative farnesyl-diphosphate farnesyl transferase (squalene synthase) involved in the sterol biosynthesis pathway; likely to be essential for growth; regulated by fluconazole and lovastatin; amphotericin B, caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1753844 1755533 + orf19.3615 1753844 1755533 1 1753844 1755533 1753971 1755452 orf19.11098|IPF23666.1|IPF5192.2|Contig4-2505_0010|orf6.3285|CA1675|CaO19.3615|CaO19.11098|IPF5192 Predicted ORF in Assemblies 19, 20 and 21; induced in core caspofungin response; increased expression observed in an ssr1 homozygous null mutant; induced by nitric oxide in yhb1 mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1754393 1754603 - ntar_455 1754393 1754603 1 1754603 1754393 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1754983 1755205 - ntar_456 1754983 1755205 1 1755205 1754983 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1755603 1757216 - orf19.3613 1755603 1757216 1 1757216 1755603 1757141 1755738 orf19.11096|IPF23668.1|IPF5194.2|Contig4-2505_0006|orf6.3283|CA1674|PAF1|CaO19.11096|CaO19.3613 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1757401 1758113 - orf19.3612 1757401 1758113 1 1758113 1757401 1758090 1757485 PST2 orf19.11095|IPF23677.1|IPF5195.2|Contig4-2505_0004|orf6.3282|CA1673|CaO19.3612|CQR2|CaO19.11095|PST21 Putative NADH:quinone oxidoreductase; similar to 1,4-benzoquinone reductase; immunogenic in mice; benomyl treatment induces transcription; oxidative stress-induced via Cap1p; fungal-specific (no human/murine homolog), farnesol-downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1757731 1757865 + ntar_457 1757731 1757865 1 1757731 1757865 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1759062 1759989 + orf19.3611 1759062 1759989 1 1759062 1759989 1759149 1759622 orf19.11094|IPF5196.2|IPF18754.2|Contig4-2505_0001|orf6.2467|orf6.3281|CA1672|CaO19.11094|CaO19.3611|IPF5196 Predicted ORF in Assemblies 19, 20 and 21; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1759899 1762007 - orf19.3610 1759899 1762007 1 1762007 1759899 1761870 1759930 orf19.11093|IPF5197|IPF23660.1|IPF5197.2|Contig4-2807_0005|orf6.2466|CA1129|CaO19.3610|CaO19.11093 Predicted ORF in Assemblies 19, 20 and 21; upregulation correlates with clinical development of fluconazole resistance [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 1762112 1763775 - orf19.3609 1762112 1763775 1 1763775 1762112 1763718 1762447 UTP15 orf19.11092|IPF23672.1|IPF5198.2|Contig4-2321_0007|orf6.2465|CA1128|CaO19.3609|CaO19.11092|IPF5198 Predicted ORF in Assemblies 19, 20 and 21; mutation confers resistance to 5-fluorocytosine (5-FC); physically interacts with TAP-tagged Nop1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1764427 1767900 + orf19.3608 1764427 1767900 1 1764427 1767900 1764507 1767620 orf19.11091|IPF23697.1|IPF5201.2|Contig4-2321_0006|orf6.2464|CA1127|CaO19.11091|MSH3|CaO19.3608 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 1767593 1769203 - orf19.3607 1767593 1769203 1 1769203 1767593 1769024 1767615 orf19.11090|IPF18812.2|IPF5203.2|Contig4-2321_0004|Contig4-2321_0005|orf6.2463|orf6.2220|CA1126|CaO19.3607|IPF5203|ECM18.3eoc Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 1768763 1769009 + ntar_458 1768763 1769009 1 1768763 1769009 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1769587 1770600 - orf19.3606 1769587 1770600 1 1770600 1769587 1770365 1769844 orf19.11089|IPF18811.1|IPF5204.2|orf6.2221|orf6.2462|CA0975|CaO19.3606|IPF18811 Predicted ORF in Assemblies 19, 20 and 21; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1770908 1772047 + orf19.3605 1770908 1772047 1 1770908 1772047 1771106 1771831 orf19.11088|IPF17165.2|IPF18755.1|Contig4-1774_0003|orf6.2222|orf6.2461|CA0976|CaO19.3605|PEX17 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1772207 1773612 + orf19.3604 1772207 1773612 1 1772207 1773612 1772272 1773420 orf19.11087|IPF18810.1|IPF17166.2|orf6.2460|orf6.2223|CA0977|CaO19.3604|IPF18810 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1773269 1773748 - ntar_459 1773269 1773748 1 1773748 1773269 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1774264 1777049 + orf19.3603 1774264 1777049 1 1774264 1777049 1774591 1776867 orf19.11086|IPF23655.1|IPF16222.2|Contig4-1896_0001|Contig4-1896_0002|orf6.2224|CA0978|CaO19.11086|CaO19.3603|IPF16222 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 1777052 1778915 + orf19.3601 1777052 1778915 1 1777052 1778915 1777186 1778829 orf19.11084|IPF23663.1|IPF19713.1|orf6.2226|CA0979|CaO19.3601|CaO19.11084|IPF19713 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1778950 1779687 + orf19.3600 1778950 1779687 1 1778950 1779687 1778986 1779687 orf19.11083|IPF23678.1|IPF17655.2|Contig4-2333_0004|orf6.2227|CA0980|CaO19.11083|CaO19.3600|IPF17655 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1779827 1783391 - orf19.3599 1779827 1783391 1 1783391 1779827 1783309 1780055 TIF4631 orf19.11082|IPF19840.2|IPF17394.3|eIF4G|Contig4-2333_0003|orf6.315|orf6.705|orf6.2228|CA0048|TIF46|CaO19.3599|IPF17394.2 Putative translation initiation factor eIF4G; overexpression causes hyperfilamentation; hyphal- and macrophage-induced; genes encoding some translation factors are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1783654 1784324 - orf19.3594 1783654 1784324 1 1784324 1783654 1784221 1783886 orf19.11076|orf6.701|CaO19.11076|CaO19.3594 Predicted ORF from Assembly 19; removed from Assembly 20; subsequently reinstated in Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1783730 1784150 + ntar_460 1783730 1784150 1 1783730 1784150 1784001 1784150 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1784369 1785771 + orf19.3593 1784369 1785771 1 1784369 1785771 1784521 1785726 RPT6 orf19.11075|IPF13102.2|IPF18846.2|Contig4-2320_0007|Contig4-2333_0001|orf6.2051|orf6.700|CA0155|CaO19.3593 Predicted ORF in Assemblies 19, 20 and 21; transcription is regulated by Mig1p; regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1785965 1788084 + orf19.3592 1785965 1788084 1 1785965 1788084 1786043 1787953 JEM1 orf19.11074|IPF19182.2|IPF13100.1|Contig4-2320_0006|orf6.2050|CA0872|CaO19.3592|IPF13100 Functional homolog of S. cerevisiae Jem1p, which acts with Scj1p and Kar2p (BiP) in protein folding and ER-associated degradation of misfolded proteins, and also has a role in karyogamy; has J domain and 4 tetratricopeptide repeats [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1788074 1789909 - orf19.3591 1788074 1789909 1 1789909 1788074 1789799 1788147 APE3 orf19.11073|IPF17873.2|IPF16625.2|Contig4-2320_0004|Contig4-2320_0005|orf6.2049|orf6.806|CA0871|CaO19.3591 Predicted ORF in Assemblies 19, 20 and 21; regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1790124 1791372 - orf19.3590 1790124 1791372 1 1791372 1790124 1791316 1790450 IPP1 orf19.11072|IPF19605.1|IPF19604.1|Contig4-2320_0001|orf6.2048|orf6.807|CA0870|CaO19.3590 Protein described as inorganic pyrophosphatase; antigenic in human, mouse; soluble protein in hyphae; macrophage-induced protein; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1791595 1792524 - orf19.3589 1791595 1792524 1 1792524 1791595 1792524 1791595 SPO11 orf19.11071|IPF19138.1|IPF14772.1|orf6.2047|orf6.808|CA0869|CaO19.3589|IPF14772 DNA endonuclease required for genetic recombination between homologous chromosomes during the parasexual cycle; produced in mitotically dividing cells; similar to S. cerevisiae Spo11p, which functions in recombination during meiosis [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1793229 1794649 + orf19.3586 1793229 1794649 1 1793229 1794649 1793412 1794308 IPF14774.2|IPF18847.1|Contig4-2332_0003|orf6.2044|orf6.2046|CA0867|CA0868|orf19.3588|IPF14773.3f|CA0190|IPF14773|orf6.809|IPF14773.2|IPF14773.exon2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1794845 1795746 + orf19.3585 1794845 1795746 1 1794845 1795746 1794949 1795341 orf19.11069|IPF23681.1|IPF14775.2|Contig4-2332_0005|orf6.2043|CA0866|CaO19.3585|CaO19.11069|IPF14775 Predicted ORF in Assemblies 19, 20 and 21; regulated by Gcn4p; repressed in response to amino acid starvation (3-aminotriazole treatment) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1795196 1796572 - orf19.225 1795196 1796572 1 1796572 1795196 1796450 1795365 orf19.7855|orf19.11068|IPF27113.1|IPF13828.1|IPF23674.1|IPF14777.1|Contig4-2332_0007|orf6.275|orf6.2042|CA0865|orf19.3584|CaO19.225|CaO19.7855 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1797532 1800237 + orf19.223 1797532 1800237 1 1797532 1800237 1797692 1800076 orf19.7854|IPF19261.2|IPF13825.2|Contig4-2835_0022|orf6.276|orf6.278|orf6.476|orf6.5150|CA3029|CaO19.223|IPF13825 Predicted ORF in Assemblies 19, 20 and 21; increased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1800309 1801837 - orf19.220 1800309 1801837 1 1801837 1800309 1801743 1800703 PIR1 orf19.7851|orf6.474|PIR2|IPF15363.2|IPF19968.1|orf6.5153|CA3030|CaO19.220|IPF19968 Structural protein of cell wall; 1,3-beta-glucan-linked; O-glycosylated by Pmt1p; N-mannosylated; tandem repeats; heterozygous mutant has cell wall defects; hyphal repressed; Hog1p, fluconazole, hypoxia induced; iron, Efg1p, Plc1p regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1807304 1807645 + orf19.218 1807304 1807645 1 1807304 1807645 1807304 1807645 BUD20 orf19.7850|IPF27125.1|IPF18392.1|orf6.5155|CaO19.7850|CaO19.218 Protein similar to S. cerevisiae Bud20p, which affects bud site selection; transposon mutation affects filamentous growth [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1809207 1810346 + orf19.217 1809207 1810346 1 1809207 1810346 1809207 1810346 orf19.7849|IPF27112.1|IPF12324.2|Contig4-2967_0001|orf6.5156|CA3031|CaO19.217|CaO19.7849|IPF12324 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1812564 1813052 + orf19.216.1 1812564 1813052 1 1812564 1813052 1812610 1812792 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1812933 1814680 - orf19.216 1812933 1814680 1 1814680 1812933 1814489 1812963 orf19.7848|IPF12319|IPF13203.3|IPF12319.2|Contig4-2967_0004|orf6.5157|orf6.28|CA3032|CaO19.216 Predicted ORF in Assemblies 19, 20 and 21; ketoconazole-induced; upregulation correlates with clinical development of fluconazole resistance [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1815934 1818034 + orf19.215 1815934 1818034 1 1815934 1818034 1816129 1817877 orf19.7847|IPF27103.1|IPF13202.1|Contig4-2967_0007|orf6.5158|CA3033|CaO19.215|AVO2|CaO19.7847|IPF13202 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1818209 1819203 + orf19.213 1818209 1819203 1 1818209 1819203 1818268 1819101 orf19.7845|IPF27114.1|IPF13198.1|Contig4-2967_0009|orf6.5160|CA3034|CaO19.213|RPN12|CaO19.7845 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1819026 1820020 - orf19.212 1819026 1820020 1 1820020 1819026 1819896 1819150 VPS28 orf19.7844|IPF27116.1|IPF13197.2|Contig4-2967_0010|orf6.5161|CA3035|CaO19.7844|CaO19.212 Protein involved in proteolytic activation of Rim101p, which regulates pH response; role in echinocandin, azole sensitivity; similar to S. cerevisiae Vps28p, which is a subunit of the ESCRT I protein sorting complex [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1820132 1821101 + orf19.211 1820132 1821101 1 1820132 1821101 1820192 1820734 orf19.7843|IPF27119.1|IPF13443.2|Contig4-2967_0012|orf6.5162|CA3036|CaO19.211|CaO19.7843|IPF13443 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1820493 1822078 - orf19.210 1820493 1822078 1 1822078 1820493 1822064 1820685 orf19.7842|IPF27111.1|IPF13442.1|Contig4-2967_0015|orf6.5163|CA3037|CaO19.210|CaO19.7842|IPF13442 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1822223 1823193 - orf19.209 1822223 1823193 1 1823193 1822223 1823162 1822314 DFG10 orf19.7841|IPF27115.1|IPF13438.2|Contig4-2967_0018|orf6.5164|CA3038|CaO19.7841|CaO19.209|IPF13438 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1823259 1824221 + ntar_461 1823259 1824221 1 1823259 1824221 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1823595 1828341 - orf19.207 1823595 1828341 1 1828341 1823595 1828161 1823947 PGA55 orf19.7838|IPF15911.3|IPF13437.3|Contig4-2967_0022|orf6.5166|orf6.5940|CA3039|CaO19.207 Putative GPI-anchored protein of unknown function; filament induced; regulated by Nrg1p, Tup1p; possibly transcriptionally regulated upon hyphal formation; mRNA binds to She3p and is localized to buds of yeast-form cells and hyphal tips [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 1828960 1829530 - ntar_462 1828960 1829530 1 1829530 1828960 1829192 1829067 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1829788 1830106 + ntar_463 1829788 1830106 1 1829788 1830106 1829892 1830041 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1830613 1834191 - orf19.206 1830613 1834191 1 1834191 1830613 1833836 1830690 orf19.7836|IPF12022.2|IPF8939.3|Contig4-2951_0014|orf6.129|orf6.5938|CA3622|CaO19.206|IPF12022 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1834301 1834564 - ntar_464 1834301 1834564 1 1834564 1834301 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1837092 1837406 - ntar_465 1837092 1837406 1 1837406 1837092 1837406 1837197 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1837111 1837865 + ntar_466 1837111 1837865 1 1837111 1837865 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1839297 1840232 - orf19.204 1839297 1840232 1 1840232 1839297 1840232 1839618 orf19.7834|IPF27117.1|IPF8942.1|Contig4-2951_0005|orf6.5936|CA3621|CaO19.204|CaO19.7834|IPF8942 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr2 1842921 1844638 + orf19.203 1842921 1844638 1 1842921 1844638 1842962 1844473 STB3 orf19.7833|IPF27108.1|IPF9063.2|Contig4-2485_0005|Contig4-2485_0007|orf6.5935|CA3620|CaO19.7833|CaO19.203|IPF9063 Predicted ORF in Assemblies 19, 20 and 21; caspofungin induced; macrophage/pseudohyphal-repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1844989 1847480 + orf19.202 1844989 1847480 1 1844989 1847480 1845016 1847361 CDC47 orf19.7832|IPF9065.2|orf6.5934|CA3619|CaO19.202|CaO19.7832|CDC47.5|MCM7 Phosphorylated protein described as having role in control of cell division; RNA abundance regulated by tyrosol and cell density; merged with orf19.201 in Assembly 20; unmerged from orf19.201 in a revision of Assembly 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1847621 1848483 + orf19.201 1847621 1848483 2 1847621|1847957 1847882|1848483 1847727 1848304 orf19.7831|IPF27100.1|IPF27124.1|IPF9065.2|IPF20139.1|Contig4-1852_0004|Contig4-2485_0003|Contig4-2485_0004|orf6.5933|orf6.5934 Predicted ORF in Assemblies 19, 20 and 21; unmerged from orf19.202 in a revision of Assembly 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1847988 1848313 - ntar_467 1847988 1848313 1 1848313 1847988 1848149 1847988 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1848635 1849436 + orf19.200 1848635 1849436 1 1848635 1849436 1848684 1849265 orf19.7830|IPF27118.1|IPF20138.1|Contig4-1852_0002|Contig4-2485_0001|orf6.5932|CA3618|CaO19.200|THO1|CaO19.7830 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1849292 1851136 - orf19.199 1849292 1851136 1 1851136 1849292 1850993 1849458 orf19.7829|IPF27109.1|IPF9069.2|Contig4-1852_0003|Contig4-1950_0007|orf6.5931|CA3617|CaO19.7829|CaO19.199|IPF9069 Predicted ORF in Assemblies 19, 20 and 21; hyphal-induced expression; greater mRNA abundance observed in a cyr1 homozygous null mutant than in wild type [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1851212 1851533 + ntar_468 1851212 1851533 1 1851212 1851533 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1851656 1853853 - orf19.198 1851656 1853853 1 1853853 1851656 1853558 1851837 ASN1 orf19.7828|IPF27104.1|IPF9072.3|Contig4-1950_0002|Contig4-1950_0005|orf6.209|orf6.5930|CaO19.198|CA3616|IPF19994.1 Protein described as asparagine synthetase; soluble protein in hyphae; regulated by Rim101p; decreased expression at pH 4 compared to pH 8 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1854235 1856933 - orf19.4066 1854235 1856933 1 1856933 1854235 1856793 1854382 orf19.7826|orf19.11549|IPF23131.1|IPF9466.2|Contig4-2273_0002|orf6.207|orf6.2484|CA1139|orf19.196|CaO19.11549|CaO19.4066|IPF9466 Predicted ORF in Assemblies 19, 20 and 21; Hog1p-downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1858879 1859507 - orf19.4067 1858879 1859507 2 1859507|1859241 1859358|1858879 1859507 1858879 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1860072 1862569 - orf19.4068 1860072 1862569 1 1862569 1860072 1862437 1860281 orf19.11551|IPF17322.2|IPF9462.2|orf6.2486|orf6.604|CA1140|CaO19.4068|IPF17322.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1862599 1863307 - orf19.4069 1862599 1863307 1 1863307 1862599 1863150 1862599 IPF9461.1|Contig4-2087_0005|orf6.2487|CA1141|CaO19.4069|IPF17322.5f Predicted ORF in Assemblies 19, 20 and 21; transcription is repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1863814 1864647 - orf19.4070 1863814 1864647 1 1864647 1863814 1864647 1863814 IPF9459.1|Contig4-2087_0002|orf6.2488|CA1142|CaO19.4070|IPF9459 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr2 1864801 1865344 + ntar_469 1864801 1865344 1 1864801 1865344 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1865590 1869294 - orf19.4072 1865590 1869294 1 1869294 1865590 1869204 1865944 IFF6 orf19.11553|HYR1-12|IPF19647.2|IPF28532.1|orf6.2490|orf6.3209|CA1621|HYR10|CaO19.4072|IPF19647.1 Putative GPI-anchored protein of unknown function; opaque-specific transcription; macrophage-induced gene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1870585 1870746 + ntar_470 1870585 1870746 1 1870585 1870746 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1872527 1876048 - orf19.4076 1872527 1876048 1 1876048 1872527 1875991 1872707 MET10 orf19.11557|IPF23180.1|IPF13194.2|Contig4-2114_0002|Contig4-2114_0003|Contig4-2114_0004|orf6.3204|CA1620|CaO19.4076|CaO19.11557 Predicted enzyme of sulfur amino acid metabolism; biofilm-induced expression; upregulated in the presence of human whole blood or polymorphonuclear (PMN) cells; Hog1p-induced; possibly adherence-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1872767 1873502 + ntar_471 1872767 1873502 1 1872767 1873502 1872964 1873119 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1880211 1882267 + orf19.4077 1880211 1882267 1 1880211 1882267 1880524 1882158 MIT1 orf19.11558|SUR1|IPF2067.2|IPF28522.1|Contig4-2072_0001|Contig4-2072_0002|orf6.3203|CA1619|CaO19.11558|CaO19.4077|IPF2067 Protein involved in sphingolipid biosynthesis; required for mannosylation of inositol phosphoceramide (IPC) to form mannosylated sphingolipids MIPC and M(IP)2C; fluconazole, caspofungin induced; macrophage-downregulated gene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1882378 1883566 + orf19.4078 1882378 1883566 1 1882378 1883566 1882509 1883522 orf19.11559|IPF2068.3|IPF28525.1|Contig4-2072_0004|orf6.3202|CA1618|RRP45|CaO19.4078|IPF2068.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1883732 1884780 + orf19.4079 1883732 1884780 1 1883732 1884780 1883770 1884561 SLP2 orf19.11560|IPF23156.1|IPF2071.3|orf6.48|orf6.6857|CA4337|CaO19.4079|IPF2071|IPF2071.2 Predicted ORF in Assemblies 19, 20 and 21; similar to stomatin mechanoreception protein [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1884965 1886262 + orf19.4080 1884965 1886262 1 1884965 1886262 1884991 1886055 orf19.11561|IPF2072.2|IPF28524.1|Contig4-3095_0004|orf6.49|orf6.6856|CA0006|CaO19.4080|IPF2072 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1886095 1886886 - ntar_1415 1886095 1886886 3 1886886|1886620|1886489 1886720|1886595|1886095 [label_first_exon=CGD label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1887648 1887862 + ntar_472 1887648 1887862 1 1887648 1887862 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1888132 1888223 + tp(ugg)2 1888132 1888223 2 1888132|1888188 1888167|1888223 tP(UGG)2.2 tRNA-Pro predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1889255 1889755 + orf19.4081 1889255 1889755 1 1889255 1889755 1889255 1889755 orf19.11562|IPF23165.1|IPF2074.1|Contig4-3095_0009|orf6.6855|CaO19.4081|CaO19.11562 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1889941 1890859 + orf19.4082 1889941 1890859 1 1889941 1890859 1889969 1890607 DDR48 orf19.11563|orf6.6854|DDR99|IPF23163.1|IPF2075.1|Contig4-3095_0012|CA4336|CaO19.11563|CaO19.4082 Immunogenic stress-associated protein; regulated by filamentous growth pathways; induced by benomyl, caspofungin, or in azole-resistant strain; Hog1p, farnesol, alkaline downregulated; similar to S. cerevisiae Ddr48p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1890822 1892346 - orf19.4084 1890822 1892346 1 1892346 1890822 1892346 1891108 KIS1 orf19.11565|IPF2078.2|IPF2079.2|Contig4-3095_0014|orf6.6852|CA4335|CaO19.4084|CaO19.11565|GAL83 Scaffold protein of Snf1p complex; similar to S. cerevisiae Gal83p and Sip2p, with regions of similarity to Sip1p (ASC and KIS domain); interacts with Snf4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1892623 1893264 - orf19.4085 1892623 1893264 1 1893264 1892623 1893264 1892623 orf19.11566|IPF23162.1|IPF2082.1|Contig4-3095_0017|orf6.6851|CA4334|CaO19.11566|CaO19.4085|IPF2082 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1893345 1894291 + orf19.4086 1893345 1894291 1 1893345 1894291 1893508 1894158 orf19.11567|IPF23158.1|IPF2083.1|Contig4-3095_0019|orf6.6850|CA4333|CaO19.4086|CaO19.11567|IPF2083 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1893978 1895067 - orf19.4088 1893978 1895067 1 1895067 1893978 1895034 1894228 orf19.11569|IPF23157.1|IPF2085.2|Contig4-3095_0020|orf6.6848|CA4332|GLO2|CaO19.11569|CaO19.4088 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1895199 1896611 - orf19.4089 1895199 1896611 1 1896611 1895199 1896546 1895305 SGT1 orf19.11570|IPF23147.1|IPF2086.2|Contig4-3095_0023|orf6.6847|CA4331|CaO19.4089|CaO19.11570|IPF2086 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to radicicol [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1896701 1898443 - orf19.4090 1896701 1898443 1 1898443 1896701 1898304 1896799 orf19.11571|IPF23141.1|IPF2087.2|Contig4-3095_0024|orf6.6846|CA4330|CaO19.11571|CaO19.4090|IPF2087 Predicted membrane transporter, member of the fucose:proton symporter (FHS) family, major facilitator superfamily (MFS) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1896732 1898410 + ntar_473 1896732 1898410 1 1896732 1898410 1898006 1898143 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1898796 1899280 + orf19.4090.1 1898796 1899280 2 1898796|1899011 1898937|1899280 1898915 1899227 IPF23132.1|IPF2089.1|orf6.3612|CA4329|VMA21 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1899317 1900526 + orf19.4091 1899317 1900526 1 1899317 1900526 1899344 1900399 orf19.11572|IPF23149.1|IPF2090.2|Contig4-3095_0028|orf6.6845|CA4328|CaO19.4091|CaO19.11572|IPF2090 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1900133 1900984 - orf19.4092 1900133 1900984 1 1900984 1900133 1900948 1900451 orf19.11573|IPF23172.1|IPF2091.2|Contig4-3095_0029|orf6.6844|CA4327|CaO19.4092|CaO19.11573|IPF2091 Predicted ORF in Assemblies 19, 20 and 21; decreased transcription is observed upon fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1901099 1902980 - orf19.4093 1901099 1902980 1 1902980 1901099 1902937 1901174 NOP7 orf19.11574|IPF23138.1|IPF2093.2|Contig4-3095_0030|orf6.6843|CA4326|PES1|CaO19.11574|CaO19.4093|IPF2093 Pescadillo homolog required for filament-to-yeast switching; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1903216 1903707 - orf19.4094 1903216 1903707 1 1903707 1903216 1903707 1903216 orf19.11575|IPF23168.1|IPF2094.2|Contig4-3095_0032|orf6.6842|CA4325|CaO19.4094|CaO19.11575|IPF2094 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1903875 1904327 + orf19.4095 1903875 1904327 1 1903875 1904327 1903875 1904327 orf19.11576|IPF23171.1|IPF2095.2|Contig4-3095_0033|orf6.6841|CA4324|CaO19.11576|CaO19.4095|IPF2095 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1904485 1906078 + orf19.4096 1904485 1906078 1 1904485 1906078 1904546 1905778 orf19.11577|IPF23146.1|IPF2096.2|Contig4-3095_0037|orf6.6840|CA4323|CaO19.11577|CaO19.4096|IPF2096 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1905912 1906111 - ntar_474 1905912 1906111 1 1906111 1905912 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1906182 1908876 + orf19.4097 1906182 1908876 1 1906182 1908876 1906243 1908816 orf19.11578|IPF23130.1|IPF2097.2|Contig4-3095_0039|Contig4-3095_0040|orf6.6839|CA4322|CaO19.4097|CaO19.11578|IPF2097 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1908791 1910979 - orf19.564 1908791 1910979 1 1910979 1908791 1910923 1908860 KAR3 orf19.11581|IPF23152.1|IPF2100.1|Contig4-3095_0041|orf6.368|orf6.6836|CA4321|orf19.4100|CA0058|IPF3770|IPF3770.2 Kinesin-like microtubule motor protein; required for nuclear fusion during mating; C-terminal motor domain; not essential for viability; homozygous null has high-frequency white-opaque switching phenotype [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1911169 1912170 + orf19.563 1911169 1912170 1 1911169 1912170 1911231 1911998 RRP15 Contig4-3095_0042|orf6.367|CaO19.563|CA0057|IPF3767|IPF3767.1 Predicted ORF in Assemblies 19, 20 and 21; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1912252 1913353 + orf19.1597 1912252 1913353 1 1912252 1913353 1912340 1913206 ABG1 orf19.9165|IPF25726.1|IPF3765.3|Contig4-3095_0044|orf6.1085|CA0299|CaO19.1597|CaO19.9165|IPF3765.3eoc|IPF3765|IPF3765.2 Vacuolar membrane protein; depletion causes abnormal vacuolar morphology, cell separation defect, sensitivity to cell wall perturbation, and increased hyphal branching; essential gene with no mammalian homolog; Cyr1p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1913126 1914828 - orf19.1598 1913126 1914828 1 1914828 1913126 1914692 1913346 ERG24 orf19.9166|IPF25723.1|IPF3764.2|Contig4-3095_0045|orf6.1086|orf6.1911|CA0300|CaO19.9166|CaO19.1598 C-14 sterol reductase, has a role in ergosterol biosynthesis; mutation confers increased sensitivity to dyclonine [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1915010 1915427 - ntar_475 1915010 1915427 1 1915427 1915010 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1917230 1917427 + ntar_476 1917230 1917427 1 1917230 1917427 1917249 1917395 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1918072 1918428 + orf19.1599 1918072 1918428 1 1918072 1918428 1918072 1918428 orf19.9167|IPF3759.2|IPF29393.1|Contig4-3095_0048|orf6.1648|CaO19.1599 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 1918754 1921595 + orf19.1600 1918754 1921595 1 1918754 1921595 1919281 1921410 orf19.9168|IPF25722.1|IPF19700.1|Contig4-3095_0049|Contig4-3095_0051|orf6.1649|CA0614|CaO19.9168|CaO19.1600|IPF19700 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1921227 1921397 - ntar_477 1921227 1921397 1 1921397 1921227 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1921910 1923165 + orf19.1601 1921910 1923165 1 1921910 1923165 1921934 1923103 RPL3 orf19.9169|IPF25724.1|IPF6742.1|Contig4-3095_0054|orf6.1650|CA0615|CaO19.1601|CaO19.9169 Putative ribosomal protein; similar to S. cerevisiae Rpl3p; gene induced by ciclopirox olamine treatment; genes encoding cytoplasmic ribosomal subunits are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1923985 1924184 + ntar_478 1923985 1924184 1 1923985 1924184 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1924256 1924773 + ntar_479 1924256 1924773 1 1924256 1924773 1924256 1924531 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1925091 1925456 + ntar_480 1925091 1925456 1 1925091 1925456 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1930174 1933641 - orf19.1604 1930174 1933641 2 1933641|1933233 1933469|1930174 1933514 1930310 orf19.9172|IPF25717.1|IPF6730.2|Contig4-3095_0062|Contig4-3095_0063|orf6.2453|CA1121|CaO19.1604|CaO19.9172|IPF6730 Predicted ORF in Assemblies 19, 20 and 21; Gal4p-like DNA-binding domain [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1935817 1936510 + ntar_481 1935817 1936510 1 1935817 1936510 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1936424 1939413 - orf19.1605 1936424 1939413 1 1939413 1936424 1939349 1936617 PMS1 orf19.9173|IPF25719.1|IPF6724.1|Contig4-3095_0066|orf6.2454|CA1122|CaO19.1605|CaO19.9173|PMS1.3eoc|PMS1.3 Protein described as DNA mismatch repair factor; ortholog of S. cerevisiae PMS1 which is an ATP-binding protein involved in DNA mismatch repair [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 1939600 1940639 + orf19.1406 1939600 1940639 1 1939600 1940639 1939666 1940436 orf19.8984|IPF25961.1|IPF19974.1|Contig4-2113_0005|Contig4-2113_0006|orf6.5359|CA3178|CaO19.8984|REV7|CaO19.1406|IPF19974 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1939881 1940646 - ntar_482 1939881 1940646 1 1940646 1939881 1940603 1940433 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1940825 1941993 + orf19.1405 1940825 1941993 1 1940825 1941993 1940951 1941916 PHO13 orf19.8983|IPF25952.1|IPF11589.2|Contig4-2113_0004|orf6.5358|CA3177|CaO19.8983|PHO132|CaO19.1405|IPF11589 Transcription is regulated upon yeast-hyphal switch [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1942078 1943561 + orf19.1404 1942078 1943561 1 1942078 1943561 1942108 1943511 orf19.8982|IPF25946.1|IPF11588.2|Contig4-2113_0003|orf6.5357|CA3176|CaO19.1404|DUS1|CaO19.8982|IPF11588 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1943491 1945486 - orf19.1403 1943491 1945486 1 1945486 1943491 1945393 1943675 orf19.8981|IPF25937.1|IPF11587.2|Contig4-2113_0002|orf6.5356|CA3175|CaO19.8981|CaO19.1403|IPF11587 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1946035 1947902 - orf19.1402 1946035 1947902 1 1947902 1946035 1947860 1946280 CCT2 orf19.8980|IPF25943.1|IPF11584.2|Contig4-2651_0001|orf6.5355|CA3174|CaO19.1402|CaO19.8980 Predicted ORF in Assemblies 19, 20 and 21; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1951311 1953653 + orf19.1401 1951311 1953653 1 1951311 1953653 1951311 1953272 EAP1 orf6.5354|PGA47|IPF7676.3|IPF14145.2|Contig4-2651_0004|CA3173|CaO19.1401|IPF14145 Cell wall adhesin required for cell-cell adhesion and biofilm formation; GPI anchored; Efg1p-regulated; suppresses polystyrene or cell adhesion, filamentation, invasive growth defects of S. cerevisiae flo8 or flo11 mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr2 1953556 1954352 - ntar_1429 1953556 1954352 2 1954352|1953840 1954291|1953556 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1954610 1957225 - orf19.1400 1954610 1957225 1 1957225 1954610 1957138 1954895 orf19.8978|IPF25931.1|IPF7679.2|Contig4-2842_0014|orf6.5353|CA3172|CaO19.1400|CSN2|CaO19.8978|IPF7676 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1957428 1959772 - orf19.1397 1957428 1959772 1 1959772 1957428 1958644 1957934 orf19.8975|IPF25962.1|IPF7681.2|Contig4-2842_0012|orf6.5350|CA3171|CaO19.1397|CaO19.8975|IPF7681 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1959636 1960319 + ntar_483 1959636 1960319 1 1959636 1960319 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1960444 1962153 + orf19.1396 1960444 1962153 1 1960444 1962153 1960784 1961947 orf19.8974|IPF25950.1|IPF7685.2|Contig4-2842_0005|orf6.5349|CA3170|AGE2|CaO19.8974|CaO19.1396|IPF7685 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1962006 1963383 - orf19.1395 1962006 1963383 1 1963383 1962006 1963177 1962161 orf19.8973|IPF11059.2|IPF7686.2|Contig4-2842_0004|orf6.5348|CA3169|CaO19.8973|CaO19.1395|IPF7686|CA0993|IPF11059|IPF11059.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1965639 1966674 - orf19.1394 1965639 1966674 1 1966674 1965639 1966535 1966035 orf19.8972|IPF11063.2|IPF29472.1|orf6.2246|orf6.5347|YCR090|CA0992|CaO19.1394|IPF11063 Protein not essential for viability; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1967279 1968806 + orf19.1393 1967279 1968806 1 1967279 1968806 1967614 1968714 orf19.8971|IPF11065.2|IPF18374.2|Contig4-2636_0009|orf6.2245|orf6.5346|CA0991|CaO19.1393|IPF11065 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1968728 1968966 - ntar_484 1968728 1968966 1 1968966 1968728 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1968909 1971388 + orf19.1392 1968909 1971388 1 1968909 1971388 1969059 1971272 orf19.8970|IPF25932.1|IPF11068.1|Contig4-2636_0008|orf6.2244|CA0990|CaO19.8970|EPS1|CaO19.1392|IPF11068 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1970690 1971979 - orf19.1391 1970690 1971979 1 1971979 1970690 1971768 1971259 orf19.8969|IPF25966.1|IPF11069.2|Contig4-2636_0007|orf6.2243|CA0989|CaO19.8969|CaO19.1391|IPF11069 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1972438 1974093 + orf19.1390 1972438 1974093 1 1972438 1974093 1972502 1973827 PMI1 orf19.8968|PMI40|IPF19894.1|IPF11071.3|Contig4-2636_0003|Contig4-2636_0004|MPI|orf6.2074|orf6.2242|CA0988|CaO19.1390 Phosphomannose isomerase; cell wall biosynthesis enzyme; drug target; functional homolog of S. cerevisiae and E. coli phosphomannose isomerase; Gcn4p-regulated; repressed by 3-AT; induced on adherence to polystyrene, phagocytosis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1974401 1975416 + orf19.1389 1974401 1975416 1 1974401 1975416 1974713 1975204 orf19.8967|IPF18804.2|IPF12381.2|Contig4-2576_0010|orf6.2075|orf6.2241|CA0885|CaO19.1389|SGN11|IPF12381 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1977023 1977334 + ntar_485 1977023 1977334 1 1977023 1977334 1977081 1977230 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 1977684 1978562 + orf19.1388 1977684 1978562 1 1977684 1978562 1977755 1978411 orf19.8966|IPF25964.1|IPF12382.2|Contig4-2576_0005|orf6.2076|CA0886|CaO19.8966|CaO19.1388|IPF12382 Predicted ORF in Assemblies 19, 20 and 21; induced upon biofilm formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1978247 1979422 - orf19.1387 1978247 1979422 1 1979422 1978247 1979358 1978474 orf19.8965|IPF25954.1|IPF12383.2|Contig4-2576_0004|orf6.2077|CA0887|CaO19.1387|CaO19.8965|IPF12383 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1979563 1980381 + orf19.1386 1979563 1980381 1 1979563 1980381 1979774 1980226 orf19.8964|IPF25970.1|IPF12385.1|Contig4-2576_0003|orf6.2078|CA0888|CaO19.1386|BET1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1980156 1982441 - orf19.1383 1980156 1982441 1 1982441 1980156 1982337 1980394 orf19.8963|IPF12388.1|IPF14542.1|IPF12387.1|Contig4-1457_0003|Contig4-1457_0005|Contig4-2576_0002|orf6.2081|orf6.2080|orf6.4169|CA6254|CA2316|orf19.1384|CaO19.1383|IPF14542.5f Predicted ORF in Assemblies 19, 20 and 21; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1982580 1983818 + orf19.1382 1982580 1983818 1 1982580 1983818 1982716 1983696 YEA4 orf19.8962|IPF14544.2|IPF12389.2|Contig4-2576_0001|orf6.2082|orf6.4168|CA2315|CaO19.1382 Protein similar to S. cerevisiae Yea4p; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1983612 1985259 - orf19.1381 1983612 1985259 1 1985259 1983612 1985123 1983729 orf19.8961|IPF25947.1|IPF14545.2|orf6.4167|CA2314|LSB5|CaO19.1381|CaO19.8961|IPF14545 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1985608 1987995 + orf19.1378 1985608 1987995 1 1985608 1987995 1985719 1987884 SUP35 orf19.8958|IPF25930.1|IPF19754.1|Contig4-2434_0007|orf6.4164|CA2313|CaO19.8958|CaO19.1378|ERF3 Translation factor eRF3; shows prion-like aggregation in some, not all, studies; partially complements S. cerevisiae sup35 mutant translation defect; species barrier with S. cerevisiae Sup35p prion; gene not regulated by yeast-hyphal switch [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1987862 1989080 - orf19.1377 1987862 1989080 1 1989080 1987862 1989007 1987955 IPK2 orf19.8957|IPF25956.1|IPF16498.2|Contig4-2434_0006|orf6.4163|CA2312|CaO19.8957|ARG82|CaO19.1377|IPF16498 Predicted ORF in Assemblies 19, 20 and 21; moderately induced at 42 deg [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1989661 1991229 + orf19.1376 1989661 1991229 1 1989661 1991229 1989931 1990818 orf19.8956|IPF25959.1|IPF16993.2|Contig4-2434_0002|Contig4-2434_0003|orf6.4162|CA2311|SSO2|CaO19.8956|CaO19.1376 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 1992133 1994191 + orf19.1375 1992133 1994191 1 1992133 1994191 1992236 1993957 LEU42 orf19.8955|IPF25939.1|IPF9877.2|Contig4-2586_0001|orf6.4161|LEU6|CA2310|CaO19.1375|CaO19.8955 Putative alpha-isopropylmalate synthase; fungal-specific (no human/murine homolog); upregulated in the presence of human blood or polymorphonuclear cells; regulated by Gcn2p and Gcn4p; detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1994376 1995450 + orf19.1374 1994376 1995450 1 1994376 1995450 1994421 1994993 orf19.8954|IPF25965.1|IPF9875.2|Contig4-2586_0002|orf6.4160|CA2309|CaO19.8954|CaO19.1374|IPF9875 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1994899 1998001 - orf19.1373 1994899 1998001 1 1998001 1994899 1997964 1995004 INP51 orf19.8953|IPF9874.2|IPF9872.3|Contig4-2586_0004|Contig4-2586_0005|orf6.1145|orf6.4159|CA2308|CaO19.1373|IPF9874.3 Putative phosphatidylinositol-4,5-bisphosphate phosphatase; involved in maintenance of phosphoinositide levels; affects hyphal growth, virulence, cell integrity; interacts with Irs4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1998083 1999021 - orf19.1372 1998083 1999021 1 1999021 1998083 1998958 1998239 orf19.8952|orf6.1146|IPF9870.2|Contig4-2586_0007|orf6.4158|orf6.530|CA6249|CaO19.1372|IPF9870 Gene transcription regulated by Mig1p and Tup1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 1999481 2001124 + orf19.1371 1999481 2001124 1 1999481 2001124 1999532 2000998 orf19.8951|IPF25945.1|IPF9869.2|orf6.1147|orf6.4157|CA0336|CaO19.1371|IPF9869 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=D scenario_last_exon=D] Ca21chr2 2001099 2002216 - orf19.1370 2001099 2002216 1 2002216 2001099 2002164 2001301 orf19.8950|IPF18486.2|IPF9867.2|Contig4-1943_0002|orf6.1148|orf6.4156|CA0337|CaO19.1370|IPF9867 Predicted ORF in Assemblies 19, 20 and 21; expression is regulated upon white-opaque switching; transcription is repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2003124 2004647 - orf19.1369 2003124 2004647 1 2004647 2003124 2004475 2003171 orf19.8949|IPF8976.2|IPF19035.2|Contig4-2176_0002|orf6.1149|orf6.5301|CA3137|PYD3|CaO19.1369|IPF8976 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2009292 2011234 + orf19.1368 2009292 2011234 1 2009292 2011234 2009389 2011215 orf19.8948|IPF25936.1|IPF8985.3|Contig4-2532_0008|orf6.291|orf6.5300|CA0045|CaO19.1368|IPF8985|IPF8985.5eoc|IPF8985.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 2012594 2013050 - orf19.1367.1 2012594 2013050 1 2013050 2012594 2012969 2012727 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2013155 2014465 + orf19.1367 2013155 2014465 1 2013155 2014465 2013271 2014215 MTW1 orf19.8947|IPF25955.1|IPF8989.1|Contig4-2532_0004|orf6.5299|CA3136|CaO19.1367|CaO19.8947|IPF8989 Kinetochore component; amount of Nuf2p and Mtw1p protein detected at each centromere is consistent with a single kinetochore microtubule attachment site [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2014327 2015586 - orf19.1366 2014327 2015586 1 2015586 2014327 2015586 2014327 orf19.8946|IPF25949.1|IPF8990.1|Contig4-2532_0003|orf6.5298|CA3135|CaO19.1366|CaO19.8946|IPF8990 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 2015944 2017517 - orf19.1365 2015944 2017517 1 2017517 2015944 2017517 2015997 orf19.8945|IPF25944.1|IPF19972.1|Contig4-1729_0002|Contig4-2532_0001|orf6.5297|CA3134|CaO19.1365|SOX1|CaO19.8945|IFZ2|IPF11499.repeat2 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to toxic ergosterol analog; constitutive expression independent of MTL or white-opaque status [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr2 2018693 2020004 + orf19.1364 2018693 2020004 1 2018693 2020004 2018811 2019848 orf19.8944|IPF25957.1|IPF16939.2|Contig4-1729_0001|orf6.5296|CA3133|YBR147w|CaO19.1364|CaO19.8944|IPF16939 Predicted ORF in Assemblies 19, 20 and 21; constitutive expression independent of MTL or white-opaque status [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2020423 2021601 - orf19.1363 2020423 2021601 1 2021601 2020423 2021601 2020423 orf19.8943|IPF25951.1|IPF8904.2|Contig4-2717_0017|orf6.5295|CA3132|CaO19.8943|CaO19.1363|IPF8904 Predicted ORF in Assemblies 19, 20 and 21; Plc1p-regulated; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr2 2024168 2025610 + orf19.1362 2024168 2025610 1 2024168 2025610 2024187 2025488 SMM1 orf19.8942|IPF25948.1|IPF8910.2|Contig4-2717_0007|orf6.5294|CA3131|CaO19.8942|CaO19.1362|IPF8910 Predicted ORF in Assemblies 19, 20 and 21; transcription is upregulated in both intermediate and mature biofilms [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2025564 2026529 - orf19.1361 2025564 2026529 1 2026529 2025564 2026312 2025656 orf19.8941|IPF25963.1|IPF8911.2|Contig4-2717_0005|orf6.5293|CA3130|CaO19.8941|TIM23|CaO19.1361 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 2026717 2027200 - orf19.1360.1 2026717 2027200 1 2027200 2026717 2027115 2026933 IPF25933.1|IPF8912.1|Contig4-2717_0004|CA3129|OST4 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 2027337 2028093 + orf19.1360 2027337 2028093 1 2027337 2028093 2027376 2027864 orf19.8940|IPF25969.1|IPF8914.1|Contig4-2717_0003|orf6.5292|CA3128|CaO19.8940|CaO19.1360|IPF8914 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 2028114 2029916 + orf19.1359 2028114 2029916 1 2028114 2029916 2028114 2029865 orf19.8939|IPF25938.1|IPF8915.1|Contig4-2717_0001|orf6.5291|CA3127|CaO19.1359|CaO19.8939|IPF8915 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 2030140 2030390 + ntar_486 2030140 2030390 1 2030140 2030390 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2030706 2032361 + orf19.1358 2030706 2032361 1 2030706 2032361 2031301 2032272 GCN4 orf19.8938|IPF25958.1|IPF8919.2|Contig4-1860_0002|orf6.5290|CA3126|CaO19.1358|CaO19.8938 Transcriptional activator of general amino acid control response; required for Efg1p-dependent pseudohyphal filament induction by amino acid starvation but not by serum; upregulated in the presence of human whole blood or PMN cells [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2032551 2033122 - ntar_487 2032551 2033122 1 2033122 2032551 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2032797 2033009 + ntar_488 2032797 2033009 1 2032797 2033009 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2033465 2033872 + ntar_489 2033465 2033872 1 2033465 2033872 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2034441 2036490 + orf19.1357 2034441 2036490 1 2034441 2036490 2034842 2036386 FCY21 orf19.8937|FCY22|IPF17673.3|IPF8921.2|IPF17777.2|IPF17779.2|Contig4-1860_0007|Contig4-1860_0009|orf6.1000|orf6.332|CA6188|FCY2|FCY21.3f High affinity, high capacity, hypoxanthine-adenine-guanine-cytosine/ H+ symporter; purine-cytosine permease of pyrimidine salvage; similar to S. cerevisiae Fcy2p; mutation confers resistance to 5-fluorocytosine (5-FC) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2036789 2037957 + orf19.1356 2036789 2037957 1 2036789 2037957 2036830 2037837 orf19.8936|IPF17674.1|IPF17112.2|Contig4-1977_0002|Contig4-1977_0003|orf6.1001|orf6.331|CA0258|CaO19.1356|MST2|IPF17112 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2037892 2039631 - orf19.1355 2037892 2039631 1 2039631 2037892 2039304 2038261 orf19.8935|IPF25953.1|IPF17111.1|Contig4-1977_0005|orf6.1002|CA0259|CaO19.8935|SOL2|CaO19.1355|SOL1 Predicted ORF in Assemblies 19, 20 and 21; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2039909 2040085 + ntar_490 2039909 2040085 1 2039909 2040085 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2040057 2040549 - ntar_491 2040057 2040549 1 2040549 2040057 2040309 2040094 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2040859 2041039 + ntar_492 2040859 2041039 1 2040859 2041039 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2041549 2042986 + orf19.1785 2041549 2042986 1 2041549 2042986 2041670 2042650 orf19.9351|IPF13018.3|IPF13017.2|Contig4-2624_0006|orf6.214|orf6.2532|CA1168|CaO19.9351|CaO19.1785|IPF13017 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2041977 2042740 - ntar_493 2041977 2042740 1 2042740 2041977 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2042855 2047509 - orf19.1783 2042855 2047509 1 2047509 2042855 2047410 2042944 YOR1 orf19.9349|orf19.9350|IPF16207.2|IPF25550.1|IPF13015.2|IPF13016.2|Contig4-2624_0003|Contig4-2624_0004|orf6.2530|orf6.2531|orf6.531|CA6193|CA6194|orf19.1784|YOR1.5f Protein similar to S. cerevisiae Yor1p, which is a plasma membrane transporter of the ATP-binding cassette (ABC) family involved in resistance to aureobasidin A; transcription is specific to white cell type [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2047932 2048177 + ntar_494 2047932 2048177 1 2047932 2048177 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2048611 2049308 - orf19.1782.1 2048611 2049308 2 2049308|2049220 2049301|2048611 2049308 2048611 ORF added to Assembly 21 based on comparative genome analysis; has intron [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 2048811 2049045 + ntar_495 2048811 2049045 1 2048811 2049045 2048923 2049045 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2049400 2050403 - orf19.1782 2049400 2050403 1 2050403 2049400 2050319 2049600 orf19.9348|IPF16210.3|IPF16646.2|Contig4-1793_0006|Contig4-2624_0009|orf6.2529|CA1167|CaO19.1782|IPF16646 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 2049406 2049707 + ntar_496 2049406 2049707 1 2049406 2049707 2049573 2049707 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2050687 2051925 - orf19.1780 2050687 2051925 1 2051925 2050687 2051925 2050687 orf19.9346|IPF25562.1|IPF16648.1|Contig4-1793_0004|orf6.2527|CA1166|CaO19.1780|CaO19.9346|IFO1 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 2053354 2054822 - orf19.1779 2053354 2054822 1 2054822 2053354 2054703 2053567 MP65 orf19.9345|SCW1|SCW10|IPF15898.1|IPF9023.3|Contig4-1875_0004|orf6.2667|CA0156|CA6263|SCW1.5f|CMP65|CaO19.1779|SCW1.3f|orf6.708 Cell surface mannoprotein; mycelial antigen; possible role in cell-wall glucan metabolism; has adhesin motif; O-glycosylation but no predicted N-glycosylation; induced by heat, upon germ tube formation, wall regeneration; diagnostic marker [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2056276 2056590 + orf19.1778 2056276 2056590 1 2056276 2056590 2056276 2056590 IPF15902.2|orf6.2666|CaO19.1778 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 2057720 2062397 + orf19.1777 2057720 2062397 1 2057720 2062397 2058113 2062261 orf19.9344|IPF25575.1|IPF9029.2|Contig4-2728_0007|orf6.2665|CA1256|CaO19.1777|UBP15|CaO19.9344 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2062302 2064365 - orf19.1776 2062302 2064365 1 2064365 2062302 2063383 2062415 orf19.9343|IPF25566.1|IPF9030.2|Contig4-2728_0006|orf6.2664|CA1255|CaO19.1776|CaO19.9343|IPF9030 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2064664 2066077 + orf19.1774 2064664 2066077 1 2064664 2066077 2064862 2066004 IPF9033.1|IPF9034.1|Contig4-2728_0003|orf6.2662|orf6.2663|CA1253|CA1254|orf19.1775|CA0636|CA0639|FDH3.3f|FDH4.3f|IPF18026.2 Predicted ORF in Assemblies 19, 20 and 21; transcription is upregulated in an RHE model of oral candidiasis; virulence-group-correlated expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2066160 2066681 - ntar_497 2066160 2066681 1 2066681 2066160 2066681 2066529 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2066856 2068533 + orf19.1773 2066856 2068533 1 2066856 2068533 2066997 2068286 RAP1 orf19.9342|IPF9036.2|IPF19909.2|Contig4-2933_0003|orf6.1679|orf6.2661|CA0635|CaO19.1773|IPF9036 Protein similar to (but shorter than) S. cerevisiae Rap1p, a transcriptional regulator that binds telomeres and regulatory sequences; binds DNA; represses hyphal growth under yeast-favoring conditions [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2068465 2071552 - orf19.1772 2068465 2071552 1 2071552 2068465 2071552 2068598 orf19.9341|IPF25546.1|IPF16267.2|Contig4-1808_0003|orf6.1678|CA0634|CaO19.1772|CaO19.9341|IPF16267 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr2 2071675 2073776 + orf19.1771 2071675 2073776 1 2071675 2073776 2071722 2073668 orf19.9340|IPF16269.2|IPF29311.1|Contig4-1714_0001|Contig4-1714_0002|orf6.1677|CA0633|CaO19.1771|CWC22|IPF16269 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 2073301 2073483 - ntar_498 2073301 2073483 1 2073483 2073301 2073483 2073310 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2073887 2074323 - ntar_499 2073887 2074323 1 2074323 2073887 2074009 2073887 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2074634 2075497 + orf19.1770 2074634 2075497 1 2074634 2075497 2074774 2075106 CYC1 orf19.9339|orf6.244|IPF25577.1|IPF17424.2|Contig4-1661_0006|CA0038|CaO19.1770|CaO19.9339 Cytochrome c; complements defects of an S. cerevisiae cyc1 cyc7 double mutant; transcriptionally regulated by iron; expression greater in high iron; alkaline downregulated; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2075713 2076974 + orf19.1769 2075713 2076974 1 2075713 2076974 2075839 2076636 orf19.9338|IPF17476.2|IPF17425.2|Contig4-1661_0003|orf6.245|orf6.2868|CA1389|PLP2|CaO19.1769 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2076182 2076755 - ntar_500 2076182 2076755 1 2076755 2076182 2076349 2076182 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2077093 2080353 + orf19.1768 2077093 2080353 1 2077093 2080353 2077093 2080227 orf19.9337|IPF25564.1|IPF25556.1|IPF6151.2|IPF17474.2|Contig4-1661_0001|Contig4-2062_0011|orf6.2869|CA1390|IPF17474.5f|IPF17474 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr2 2080524 2080761 - ntar_501 2080524 2080761 1 2080761 2080524 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2080976 2083096 + orf19.1767 2080976 2083096 1 2080976 2083096 2081249 2083090 orf19.9336|IPF25557.1|IPF6149.2|Contig4-2062_0005|Contig4-2062_0006|orf6.2870|CA1392|CaO19.9336|CaO19.1767|IPF6149 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 2083085 2083413 - ntar_502 2083085 2083413 1 2083413 2083085 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2084490 2085695 + orf19.1766 2084490 2085695 1 2084490 2085695 2084490 2085695 orf19.9335|IPF25563.1|IPF6146.2|Contig4-2031_0001|orf6.2871|CA1393|CaO19.9335|CaO19.1766|IFO3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 2085834 2086104 - ntar_503 2085834 2086104 1 2086104 2085834 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2088477 2090189 + orf19.1765 2088477 2090189 1 2088477 2090189 2088810 2090066 orf19.9334|IPF19560.1|IPF19561.2|Contig4-2450_0006|orf6.189|orf6.2872|CA1394|CaO19.1765|IFO2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 2090060 2091745 - orf19.1764 2090060 2091745 1 2091745 2090060 2091410 2090562 orf19.9333|IPF16551.2|IPF29314.1|Contig4-2450_0007|orf6.2873|orf6.4085|CA6192|CaO19.1764|IPF29314 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2093348 2094460 + orf19.1763 2093348 2094460 1 2093348 2094460 2093348 2094460 IFR1 orf19.9332|IPF17558.3|IPF17956.2|orf6.4086|CA2258|FZD5|CaO19.1763|CA1395|IPF17558|IPF17558.2 Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr2 2094402 2095579 - orf19.1762 2094402 2095579 1 2095579 2094402 2095472 2094663 OCA1 orf19.9331|IPF25568.1|IPF6845.2|Contig4-1964_0001|orf6.4087|CA2259|CaO19.1762|IPF6845 Putative protein phosphatase of the PTP family (tyrosine-specific), similar to S. cerevisiae Oca1p; mutant shows virulence defect; not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2095729 2096510 + orf19.1761 2095729 2096510 1 2095729 2096510 2095818 2096333 orf19.9330|IPF25572.1|IPF6848.1|Contig4-1964_0004|orf6.4088|CA2260|OST2|CaO19.9330|CaO19.1761 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2096362 2097803 - orf19.1760 2096362 2097803 1 2097803 2096362 2097593 2096718 RAS1 orf19.9329|IPF25567.1|IPF6849.2|Contig4-1964_0005|orf6.4089|CA2261|CaO19.9329|CaO19.1760 RAS signal transduction GTPase; regulates cAMP and MAP kinase pathways; role in hyphal induction, virulence, apoptosis, heat-shock sensitivity; nonessential; glutamine-rich C terminus; complements viability of S. cerevisiae ras1 ras2 mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2097930 2098448 - ntar_504 2097930 2098448 1 2098448 2097930 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2098732 2100771 - orf19.1759 2098732 2100771 1 2100771 2098732 2100586 2099138 PHO23 orf19.9328|IPF6854.2|IPF29313.1|Contig4-1958_0002|orf6.4090|orf6.925|CA0227|CaO19.1759 Protein not essential for viability; similar to S. cerevisiae Pho23p, which is a probable component of the Rpd3 histone deacetylase complex [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2099039 2099247 + ntar_505 2099039 2099247 1 2099039 2099247 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2101793 2102146 + ntar_506 2101793 2102146 1 2101793 2102146 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2102739 2104804 + orf19.1757 2102739 2104804 1 2102739 2104804 2102914 2104665 orf19.9326|IPF25560.1|IPF6857.1|Contig4-2851_0019|orf6.4092|CA2262|CaO19.9326|CaO19.1757|IPF6857 Putative transcription factor with zinc finger DNA-binding motif; transcription is upregulated in clinical isolates from HIV+ patients with oral candidiasis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2106621 2106939 + ntar_507 2106621 2106939 1 2106621 2106939 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2107158 2109164 + orf19.1756 2107158 2109164 1 2107158 2109164 2107827 2109038 GPD1 orf19.9325|IPF25561.1|IPF6860.1|Contig4-2851_0007|orf6.4093|CA2263|CaO19.1756|CaO19.9325 Protein similar to S. cerevisiae glycerol-3-phosphate dehydrogenase (enzyme of glycerol biosynthesis); biofilm-induced expression; regulated by Efg1p; regulated by Tsa1p, Tsa1Bp under H2O2 stress conditions [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2107193 2107398 - ntar_508 2107193 2107398 1 2107398 2107193 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2109176 2111954 - orf19.1755 2109176 2111954 1 2111954 2109176 2111839 2109305 SET2 orf19.9324|IPF25548.1|IPF6862.2|Contig4-2851_0005|Contig4-2851_0006|orf6.4094|CA2264|CaO19.1755|CaO19.9324 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2112053 2113990 - orf19.1754 2112053 2113990 1 2113990 2112053 2113841 2112408 orf19.9323|IPF16060.2|IPF6866.1|Contig4-2851_0003|orf6.1077|orf6.4095|CA2265|CMK2|CaO19.1754 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2114489 2116887 + orf19.1753 2114489 2116887 1 2114489 2116887 2114501 2116780 PUS7 orf19.9322|IPF16061.2|IPF6867.2|Contig4-2851_0001|orf6.1078|orf6.4096|CA0294|CaO19.1753|IPF16061 Protein similar to S. cerevisiae tRNA modification protein; induced upon biofilm formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2116819 2119549 - orf19.1751 2116819 2119549 1 2119549 2116819 2119291 2117063 SPT23 orf19.9320|IPF25551.1|IPF10741.2|orf6.1080|orf6.1828|CA0726|MGA2|CaO19.1751|IPF10741 Protein involved in regulation of unsaturated fatty acid biosynthesis; controls the expression of the Ole1p delta-9-fatty acid desaturase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2119616 2120271 + ntar_509 2119616 2120271 1 2119616 2120271 2119616 2119831 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2120498 2122811 + orf19.1750 2120498 2122811 2 2120498|2121881 2121038|2122811 2120962 2122595 orf19.9319|IPF25570.1|IPF10745.2|Contig4-2591_0005|Contig4-2591_0006|orf6.1827|CaO19.9319|CaO19.1750 Predicted ORF in Assemblies 19, 20 and 21; similar to mammalian SR-like RNA splicing factor; gene has intron; significant changes made to ORF with coordinate updates (see Locus History) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 2122811 2124948 - orf19.1748 2122811 2124948 1 2124948 2122811 2124870 2122825 orf19.9316|IPF19639.1|IPF19640.2|Contig4-2591_0004|orf6.1825|orf6.2021|CA0853|CaO19.1748|IPF19640 Predicted ORF in Assemblies 19, 20 and 21; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr2 2125354 2127580 - orf19.1747 2125354 2127580 1 2127580 2125354 2127438 2125441 KIP2 orf19.9315|IPF10752.2|IPF16668.3|Contig4-2591_0011|orf6.2020|orf6.86|CA0852|CaO19.1747 Protein similar to S. cerevisiae Kip2p; transcription is repressed in response to alpha pheromone in SpiderM medium; periodic mRNA expression, peak at cell-cycle G2/M phase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2127772 2129101 + ntar_510 2127772 2129101 1 2127772 2129101 2128312 2128587 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2127819 2129144 - orf19.1746 2127819 2129144 1 2129144 2127819 2129144 2127819 orf19.9313|IPF16670.2|IPF10753.2|Contig4-2199_0007|orf6.2018|orf6.85|CA0851|Ca38F10.06|CaO19.1746|SSP2|IPF16670 Predicted ORF in Assemblies 19, 20 and 21; similar to S. cerevisiae meiosis-specific, spore-wall-localized protein Ssp2p, which is required for wild-type formation of outer spore wall in S. cerevisiae [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 2129334 2130976 - orf19.1745 2129334 2130976 1 2130976 2129334 2129898 2129404 orf19.9312|IPF16671.1|IPF15008.3|Contig4-2199_0006|orf6.2017|orf6.70|CA0850|LDG1|CaO19.1745|IPF16671 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2131084 2132090 + orf19.1744 2131084 2132090 1 2131084 2132090 2131163 2131978 HEM4 orf19.9311|orf6.2016|orf6.69|IPF15006.2|IPF19454.2|Contig4-2199_0003|CA0849|CaO19.1744 Protein described as uroporphyrinogen III synthase; transcriptionally regulated by iron; expression greater in high iron or elevated CO2; alkaline downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2132019 2134537 - orf19.1743 2132019 2134537 1 2134537 2132019 2134268 2132241 ACS1 orf19.9310|IPF25554.1|IPF15005.2|Contig4-2199_0001|orf6.2015|CA0848|CaO19.9310|CaO19.1743 Putative acetyl-CoA synthetase, similar to S. cerevisiae Acs1p; upregulated in the presence of human neutrophils; fluconazole-downregulated; regulated by Nrg1p and Mig1p; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2136958 2138671 - orf19.1742 2136958 2138671 1 2138671 2136958 2138454 2137432 HEM3 orf19.9309|orf6.1095|IPF25565.1|IPF15629.3|Contig4-2299_0001|Contig4-2299_0002|CA0306|CaO19.1742|CaO19.9309|IPF15629.2 Hydroxymethylbilane synthase (uroporphyrinogen I synthase); catalyzes conversion of 4-porphobilinogen to hydroxymethylbilane, the third step in the heme biosynthetic pathway; transcription greater in high iron, CO2; alkaline downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2139918 2140416 + ntar_511 2139918 2140416 1 2139918 2140416 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2140549 2140775 + ntar_512 2140549 2140775 1 2140549 2140775 2140575 2140775 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2141384 2141571 - ntar_513 2141384 2141571 1 2141571 2141384 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2151608 2153146 + orf19.3490 2151608 2153146 1 2151608 2153146 2151608 2153146 FGR6-4 IPF12875.1|Contig4-2681_0014|CA6237|CaO19.3490|IFV10 Protein lacking an ortholog in S. cerevisiae; member of a family encoded by FGR6-related genes in the RB2 repeat sequence; transposon mutation affects filamentous growth [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 2156279 2159145 - orf19.5316 2156279 2159145 1 2159145 2156279 2159079 2156749 FGR29 orf19.12776|IPF21826.1|IPF817.1|Contig4-2899_0017|orf6.8305|CA5483|CaO19.5316|CaO19.12776|IPF817 Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2159252 2162363 - orf19.5318 2159252 2162363 1 2162363 2159252 2162337 2159425 RAD1 orf19.12778|orf19.12779|IPF21839.1|IPF815.2|Contig4-2899_0012|Contig4-2899_0014|orf6.8307|orf6.8308|CA5484|CA5485|orf19.5319|RAD1.53f|RAD1.3f Transcription is regulated by Nrg1p; macrophage-induced gene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2162456 2163226 + orf19.5320 2162456 2163226 1 2162456 2163226 2162539 2163045 NCE4 orf19.12780|IPF21883.1|IPF813.1|Contig4-2899_0010|orf6.8309|CA5486|CaO19.12780|CaO19.5320|IPF813 Predicted ORF in Assemblies 19, 20 and 21; periodic mRNA expression, peak at cell-cycle G2/M phase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2162917 2165078 - orf19.5321 2162917 2165078 1 2165078 2162917 2164985 2163063 orf19.12781|IPF21834.1|IPF812.1|Contig4-2899_0009|orf6.8310|CA5487|CaO19.5321|MET12|CaO19.12781 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2165323 2166267 - orf19.5322 2165323 2166267 1 2166267 2165323 2166211 2165453 orf19.12782|IPF21870.1|IPF810.1|Contig4-2899_0005|orf6.8311|CA5488|ATG27|CaO19.12782|CaO19.5322|IPF810 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2166535 2167734 + orf19.5323 2166535 2167734 1 2166535 2167734 2166626 2167654 MDH1-3 orf19.12783|IPF21860.1|IPF807.1|MDH12|Contig4-2899_0003|orf6.8312|CA5489|MDH3|CaO19.12783|CaO19.5323 Predicted malate dehydrogenase; farnesol regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2167572 2167874 - tv(uac)1 2167572 2167874 2 2167874|2167814 2167837|2167572 tV(UAC)1.2 tRNA-Val predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 2168512 2168599 + tf(gaa)4 2168512 2168599 2 2168512|2168564 2168548|2168599 tF(GAA)4.2 tRNA-Phe predicted by tRNAscan-SE; has atypical tertiary T15A48 basepair (rather than R15Y48 basepair) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 2169370 2169780 + ntar_514 2169370 2169780 1 2169370 2169780 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2169709 2171072 - orf19.5325 2169709 2171072 1 2171072 2169709 2171046 2169760 KIN3 orf19.12785|IPF21850.1|IPF802.1|Contig4-2899_0018|orf6.8314|CA5490|CaO19.12785|CaO19.5325 Protein similar to S. cerevisiae Kin3p; induced under Cdc5p depletion; shows Mob2p-dependent hyphal regulation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2171278 2172139 + orf19.5326 2171278 2172139 1 2171278 2172139 2171303 2172112 orf19.12786|IPF796.2|IPF798.1|orf6.8315|CA5491|CaO19.5326|MIG2|CaO19.12786|IPF798 Putative transcription factor with zinc finger DNA-binding motif; possible ortholog of S. cerevisiae Mig2p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2172002 2179376 - orf19.5328 2172002 2179376 1 2179376 2172002 2179365 2172118 GCN1 orf19.12788|orf19.12789|orf19.12793|IPF21822.1|IPF797.1|Contig4-3102_0061|orf6.8317|orf6.8322|orf6.8318|CA5492|CA5493|orf19.5329|orf19.5333|GCN1.3f Protein not essential for viability; similar to S. cerevisiae Gcn1p, which is a regulator of the protein kinase Gcn2p involved in translation initiation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2179364 2179943 + ntar_515 2179364 2179943 1 2179364 2179943 2179364 2179528 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2179713 2180453 - orf19.5334 2179713 2180453 1 2180453 2179713 2180422 2179811 orf19.12794|IPF21876.1|IPF785.1|Contig4-3102_0060|orf6.8323|CA5494|CaO19.12794|TIS11|CaO19.5334|IPF85 Predicted ORF in Assemblies 19, 20 and 21; transcription regulated upon yeast-hyphal switch [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2181282 2184965 + orf19.5335 2181282 2184965 1 2181282 2184965 2181357 2184926 SGS1 orf19.12795|IPF21906.1|IPF783.1|Contig4-3102_0059|orf6.8324|CA5495|CaO19.5335|CaO19.12795 Protein described as a DNA helicase; haploinsufficient for wild-type lifespan; upregulated upon treatment of biofilm with farnesol [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 2184855 2185734 - ntar_516 2184855 2185734 1 2185734 2184855 2185049 2184855 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2185029 2185713 + orf19.5337 2185029 2185713 1 2185029 2185713 2185048 2185575 UBC15 orf19.12797|IPF21878.1|IPF779.1|Contig4-3102_0058|orf6.8326|CA5496|CaO19.12797|CaO19.5337|IPF779 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 2185889 2186078 - ntar_517 2185889 2186078 1 2186078 2185889 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2186303 2187484 + orf19.5338 2186303 2187484 1 2186303 2187484 2186699 2187484 GAL4 orf19.12798|IPF21869.1|IPF776.1|Contig4-3102_0054|orf6.8327|CA5497|CaO19.5338|CaO19.12798|IPF776 Transcription factor with zinc cluster DNA-binding motif involved in control of glycolysis; ortholog of S. cerevisiae Gal4p, but not involved in the regulation of galactose utilization genes; caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 2187529 2188041 + orf19.5339 2187529 2188041 1 2187529 2188041 2187529 2187873 orf19.12799|IPF21907.1|IPF28082.1|orf6.8328|CaO19.12799|CaO19.5339 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 2188130 2189791 + orf19.5340 2188130 2189791 1 2188130 2189791 2188145 2189791 orf19.12800|IPF21844.1|IPF772.1|Contig4-3102_0051|Contig4-3102_0052|orf6.8329|CA5498|CaO19.12800|CaO19.5340|IPF772 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 2189804 2190749 + orf19.5341 2189804 2190749 1 2189804 2190749 2189961 2190749 RPS4A orf19.12801|IPF21871.1|IPF771.1|Contig4-3102_0050|orf6.8330|CA5499|RPS4|RPS41|CaO19.5341|CaO19.12801 Predicted ribosomal protein; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage; transcription is positively regulated by Tbf1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 2190842 2192597 + orf19.5342 2190842 2192597 1 2190842 2192597 2190842 2192530 orf19.12802|IPF21840.1|IPF768.1|Contig4-3102_0049|orf6.8331|CA5500|CaO19.12802|CaO19.5342|IPF768 Predicted ORF in Assemblies 19, 20 and 21; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 2192513 2193257 - orf19.5342.1 2192513 2193257 2 2193257|2193069 2193127|2192513 2193142 2192540 MTR2 IPF21880.1|IPF767.1|Contig4-3102_0046|CA5501|MTR2.3f|MTR2.3 Nuclear export protein; member of NTF2 family; monomeric in solution; interacts with Mex67p via the NTF2-like domain [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 2193258 2193786 + orf19.5342.2 2193258 2193786 1 2193258 2193786 2193483 2193671 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2194359 2196100 + orf19.5343 2194359 2196100 1 2194359 2196100 2194673 2196022 ASH1 orf19.12803|orf6.8332|IPF21849.1|IPF763.2|Contig4-3102_0043|CA5502|CaO19.5343|CaO19.12803|IPF763 GATA-like transcription factor; localizes to nuclei of daughter cells and hyphal tip cells; mRNA localization is mediated by binding to She3p; required for wild-type virulence and filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 2195243 2196052 - ntar_518 2195243 2196052 1 2196052 2195243 2195579 2195373 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr2 2196190 2197338 + orf19.5345 2196190 2197338 1 2196190 2197338 2196208 2197227 orf19.12805|IPF21861.1|IPF761.1|Contig4-3102_0041|orf6.8334|CA5503|DSK2|CaO19.5345|CaO19.12805 Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide in yhb1 mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 2197368 2198605 + orf19.5346 2197368 2198605 1 2197368 2198605 2197387 2198598 orf19.12806|IPF21852.1|IPF758.1|Contig4-3102_0038|orf6.8335|CA5504|CaO19.5346|TAF65|CaO19.12806 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 2198860 2202012 + orf19.5348 2198860 2202012 2 2198860|2198968 2198905|2202012 2198883 2201968 TPS3 orf19.12808|IPF21920.1|IPF753.1|Contig4-3102_0037|orf6.8337|CA5505|TPS3.3 Protein described as regulatory subunit of trehalose-phosphate synthase; regulated by Efg1p; biofilm-repressed expression; regulated by Tsa1p, Tsa1Bp under H2O2 stress conditions [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 2201935 2202856 - orf19.5350 2201935 2202856 1 2202856 2201935 2202837 2201965 orf19.12810|IPF21867.1|IPF748.1|Contig4-3102_0035|orf6.8339|CA5506|CaO19.5350|CTK3|CaO19.12810|IPF748 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2203000 2203724 + orf19.5351 2203000 2203724 1 2203000 2203724 2203030 2203494 TIF11 orf19.12811|IPF21884.1|IPF747.1|Contig4-3102_0034|orf6.8340|CA5507|CaO19.12811|CaO19.5351 Predicted translation initiation factor eIF1a; possibly transcriptionally regulated upon hyphal formation; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2203538 2204839 - orf19.5352 2203538 2204839 1 2204839 2203538 2204722 2203616 orf19.12812|IPF745|IPF21859.1|IPF745.1|Contig4-3102_0032|orf6.8341|CA5508|CaO19.5352|CaO19.12812 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2205013 2205987 + orf19.5353 2205013 2205987 1 2205013 2205987 2205013 2205987 orf19.12813|IPF21863.1|IPF743.1|Contig4-3102_0028|Contig4-3102_0029|orf6.8342|CA5509|CaO19.5353|CaO19.12813|IPF743 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr2 2205530 2208740 - orf19.5356 2205530 2208740 1 2208740 2205530 2208734 2205984 orf19.12816|IPF21819.1|IPF741.1|Contig4-3102_0027|orf6.8345|CA5510|CaO19.12816|CaO19.5356|IPF741 Predicted ORF in Assemblies 19, 20 and 21; downregulated during core stress response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 2208854 2211108 - orf19.5357 2208854 2211108 1 2211108 2208854 2211088 2208884 AKL1 orf19.12817|IPF21828.1|IPF737.1|Contig4-3102_0024|Contig4-3102_0025|orf6.8346|CA5511|CaO19.5357|CaO19.12817 Protein induced during the mating process [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 2211188 2213298 - orf19.5358 2211188 2213298 1 2213298 2211188 2213298 2211232 orf19.12818|IPF21829.1|IPF733.1|Contig4-3102_0023|orf6.8347|CA5512|CaO19.12818|ORC2|CaO19.5358 Phosphorylated protein of unknown function; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 2213339 2214045 + orf19.5360 2213339 2214045 1 2213339 2214045 2213416 2213751 RPC11 orf19.12820|IPF21901.1|IPF731.1|Contig4-3102_0022|orf6.8349|CA5513|CaO19.5360|CaO19.12820 Predicted ORF in Assemblies 19, 20 and 21; downregulated in core caspofungin response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2213729 2215361 - orf19.5362 2213729 2215361 1 2215361 2213729 2215361 2213748 PSO2 orf19.12822|IPF21842.1|IPF730.1|Contig4-3102_0020|Contig4-3102_0021|orf6.8351|CA5514|CaO19.12822|CaO19.5362|IPF730 Predicted ORF in Assemblies 19, 20 and 21; expressed in opaque or white MTLa/MTLa or MTLalpha/MTLalpha, but not MTLa/MTLalpha cells; telomere-proximal gene; mutation does not affect white-to-opaque phenotypic switching [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 2215409 2216216 - orf19.5363 2215409 2216216 1 2216216 2215409 2216084 2215425 orf19.12823|IPF21873.1|IPF728.1|Contig4-3102_0019|orf6.8352|CA5515|CaO19.12823|CaO19.5363|SAT2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 2215417 2217650 + orf19.5364 2215417 2217650 2 2215417|2216398 2216211|2217650 2216503 2217414 orf19.12824|IPF21865.1|IPF726.1|Contig4-3102_0016|orf6.8353|CA5516|ECM2|CaO19.5364|CaO19.12824|IPF726 Predicted ORF in Assemblies 19, 20 and 21; intron in 5'-UTR [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr2 2217188 2221143 - orf19.5365 2217188 2221143 1 2221143 2217188 2221049 2217417 orf19.12825|orf19.12826|IPF721.3f|IPF21841.1|IPF724.2|IPF721.5f|Contig4-3102_0014|Contig4-3102_0015|orf6.8354|orf6.8355|CA5517|CA5518|orf19.5366 Predicted ORF in Assemblies 19, 20 and 21; decreased transcription is observed upon fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2221122 2221616 + orf19.5365.1 2221122 2221616 1 2221122 2221616 2221316 2221564 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 2221673 2224063 + orf19.5367 2221673 2224063 1 2221673 2224063 2221673 2224063 RDH54 orf19.12827|IPF21823.1|IPF718.1|Contig4-3102_0011|orf6.8356|CA5519|CaO19.12827|CaO19.5367 Protein described as having role in DNA recombination, repair; transcriptionally induced by interaction with macrophage [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr2 2223920 2225674 - orf19.5368 2223920 2225674 1 2225674 2223920 2225673 2224060 orf19.12828|IPF21843.1|IPF714.1|Contig4-3102_0010|orf6.8357|CA5520|CaO19.12828|CaO19.5368|IPF714 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2225884 2227061 - orf19.5369 2225884 2227061 1 2227061 2225884 2227017 2225932 orf19.12829|IPF21858.1|IPF712.1|Contig4-3102_0008|orf6.8358|CA5521|HEM12|CaO19.5369|CaO19.12829 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr2 2227464 2228636 + orf19.5370 2227464 2228636 1 2227464 2228636 2227467 2228636 orf19.12830|IPF21856.1|IPF708.1|Contig4-2210_0006|Contig4-3079_0036|Contig4-3102_0006|orf6.8359|CA5522|CaO19.12830|CaO19.5370|IPF708 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chr2 2228892 2229916 - ntar_519 2228892 2229916 1 2229916 2228892 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1028 1254 - ntar_520 1028 1254 1 1254 1028 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1386 2040 - ntar_521 1386 2040 1 2040 1386 1711 1508 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 2182 3825 + ntar_522 2182 3825 1 2182 3825 2979 3164 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 3616 4880 - orf19.5474 3616 4880 1 4880 3616 4880 3828 orf19.12929|IPF21741.1|IPF2681.1|orf6.8710|CaO19.5474|CaO19.12929 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction); transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 3999 4823 + orf19.5475 3999 4823 1 3999 4823 3999 4823 IPF21738.1|IPF2680.1|orf6.6377|orf6.8711 [NOT TRANSCRIBED?] ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 4903 8097 - orf19.5469 4903 8097 1 8097 4903 8097 4903 orf19.12924|IPF21813.1|IPF2690.1|Contig4-2935_0001|orf6.1630|orf6.6371|orf6.8705|YRF1|CaO19.5469|CaO19.12924 Predicted ORF in Assemblies 19, 20 and 21; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 5971 7002 + orf19.5472 5971 7002 1 5971 7002 5971 7002 IPF20006.2|IPF2686.1|orf6.6374|orf6.8708 [NOT TRANSCRIBED?] ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 8212 8532 - ntar_523 8212 8532 1 8532 8212 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 13756 14265 + orf19.5467 13756 14265 1 13756 14265 13756 14265 TLO7 orf19.12922|IPF21767.1|IPF4141.1|orf6.8703|CA5808|TLO7b|CaO19.5467|CTA225|CaO19.12922|CTA20.5f Member of a family of telomere-proximal genes of unknown function; may be spliced in vivo [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 15461 15592 - ntar_524 15461 15592 1 15592 15461 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 15852 16357 + orf19.5466 15852 16357 1 15852 16357 15901 16308 RPS24 orf19.12921|IPF21774.1|IPF4146.1|RPS24A|Contig4-3013_0008|orf6.8702|CA5807|CaO19.5466|CaO19.12921 Predicted ribosomal protein; hyphal downregulated; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage; transcription activated by Tbf1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 16407 17105 + orf19.5465 16407 17105 1 16407 17105 16407 17105 orf19.12920|IPF21752.1|IPF4149.1|Contig4-3013_0009|orf6.8701|CA5806|CaO19.5465|YJU2|CaO19.12920|IPF4149 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 16960 19538 - orf19.5463 16960 19538 1 19538 16960 19533 17074 orf19.12918|IPF21695.1|IPF4153.2|Contig4-3013_0010|Contig4-3013_0013|orf6.8699|CA5805|SEC6|CaO19.5463|CaO19.12918|IPF4153 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 17482 18108 + orf19.5464 17482 18108 1 17482 18108 17482 18108 IPF21744.1|IPF4152.1|orf6.8700 [NOT TRANSCRIBED?] ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 19578 21197 - orf19.5459 19578 21197 1 21197 19578 21179 19602 orf19.12914|IPF21717.1|IPF4160.1|Contig4-3013_0014|orf6.8695|CA5804|PBP1|CaO19.5459|CaO19.12914|IPF4160 Putative protein of unknown function, transcription is upregulated in an RHE model of oral candidiasis and in clinical isolates from HIV+ patients with oral candidiasis; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 19605 20204 + orf19.5462 19605 20204 1 19605 20204 19605 20204 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 20107 20643 + orf19.5461 20107 20643 1 20107 20643 20107 20643 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 21254 22687 - orf19.5457 21254 22687 1 22687 21254 22687 21254 orf19.12912|IPF21728.1|IPF4163.1|Contig4-3013_0015|orf6.8693|CA5803|CaO19.12912|CaO19.5457|IPF4163 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 22745 23092 - orf19.5455 22745 23092 1 23092 22745 23092 22745 orf19.12910|IPF21791.1|IPF4164.1|Contig4-3013_0017|orf6.8691|CA5802|CaO19.12910|VTC1|CaO19.5455|IPF4164 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 23153 24971 - orf19.5454 23153 24971 1 24971 23153 24971 23211 DAL1 orf19.12909|IPF21709.1|IPF4171.1|Contig4-3013_0020|orf6.8690|CA5801|CaO19.12909|CaO19.5454 Predicted ORF in Assemblies 19, 20 and 21; transcription is regulated by Nrg1p and Mig1p; macrophage/pseudohyphal-repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 23640 23894 + ntar_525 23640 23894 1 23640 23894 23640 23894 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 24430 24810 + orf19.5451 24430 24810 1 24430 24810 24430 24810 IPF21764.1|IPF4170.1|orf6.8687 ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 25025 26275 - orf19.5450 25025 26275 1 26275 25025 26266 25109 orf19.12905|IPF18064.2|IPF4175.1|Contig4-3013_0021|orf6.8686|CA5800|CaO19.5450|ETR1|CaO19.12905|IPF4175 Predicted ORF in Assemblies 19, 20 and 21; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr3 26339 26985 - orf19.5449 26339 26985 1 26985 26339 26975 26343 orf19.12904|IPF21758.1|IPF4176.1|Contig4-3013_0023|orf6.8685|CA5799|CaO19.12904|CaO19.5449|IPF4176 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 28278 30196 + orf19.5447 28278 30196 1 28278 30196 28278 30170 HGT19 orf19.12902|ITR1|IPF21705.1|IPF4181.1|Contig4-3013_0026|orf6.8683|CA5798|CaO19.5447|CaO19.12902|IPF4181 Putative glucose/myo-inositol transporter of major facilitator superfamily; 12 transmembrane segments, extended N terminus; expressed in rich medium, 2% glucose; phagocytosis-induced; C. albicans glucose transporter family has 20 members [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr3 29708 30205 - orf19.5446 29708 30205 1 30205 29708 30205 29708 IPF21760.1|IPF4182.1|orf6.8682|CA5797|CaO19.12901|CaO19.5446|IPF4182 Putative protein of unknown function, transcription is upregulated in clinical isolates from HIV+ patients with oral candidiasis; regulated by Ssn6p; ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 30220 31575 - orf19.5445 30220 31575 1 31575 30220 31575 30220 GLO3 orf19.12900|IPF21730.1|IPF4185.1|Contig4-3013_0028|orf6.8681|CA5796|CaO19.5445|CaO19.12900 Protein not essential for viability; similar to S. cerevisiae Glo3p, which is a GTPase-activating protein for ADP-ribosylation factors [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 31632 33045 - orf19.5444 31632 33045 1 33045 31632 32992 31718 orf19.12899|IPF21736.1|IPF4189.1|Contig4-3013_0030|orf6.8680|CA5795|TIM44|CaO19.12899|CaO19.5444 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 33058 34476 - orf19.5443 33058 34476 1 34476 33058 34464 33094 orf19.12898|IPF21731.1|IPF4191.1|Contig4-3013_0031|orf6.8679|YBL098W|CA5794|CaO19.5443|BNA4|CaO19.12898|IPF4191 Putative kynurenine 3-monooxygenase, involved in NAD biosynthesis; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 34514 36088 - orf19.5442 34514 36088 1 36088 34514 36054 34558 orf19.12897|IPF21720.1|IPF4192.1|orf6.8678|CA5793|CaO19.12897|CaO19.5442|IPF4192 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 36127 38813 - orf19.5441 36127 38813 1 38813 36127 38813 36189 ULP3 orf19.12896|IPF21693.1|IPF4195.1|orf6.8677|CA5792|CaO19.12896|ULP2|CaO19.5441|IPF4195 Putative SUMO deconjugation enzyme that removes the small ubiquitin-like modifier (SUMO) from proteins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 39136 40592 + orf19.5440 39136 40592 1 39136 40592 39195 40592 RPT2 orf19.12895|IPF21719.1|IPF4196.2|Contig4-2435_0006|orf6.8676|CA5791|CaO19.5440|CaO19.12895 Predicted ORF in Assemblies 19, 20 and 21; oxidative stress-induced via Cap1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 40606 43063 + orf19.5439 40606 43063 1 40606 43063 40606 42942 orf19.12894|IPF21698.1|IPF1144.2|orf6.8675|CA5790|CaO19.12894|CaO19.5439|IPF1144 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 42227 43446 - orf19.5438 42227 43446 1 43446 42227 43340 42951 orf19.12893|IPF21785.1|IPF1143.1|orf6.8674|CA5789|CaO19.5438|CaO19.12893|IPF1143 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 44953 45998 + orf19.5437 44953 45998 1 44953 45998 45115 45879 RHR2 orf19.12892|GPP1|IPF21745.1|IPF1139.1|Contig4-2896_0003|orf6.8673|CA5788|CaO19.12892|CaO19.5437 Putative glycerol 3-phosphatase; roles in osmotic tolerance, glycerol accumulation in response to salt; regulated by macrophage, stress response, yeast-hyphal switch, pheromone, GCN4, HOG1, NRG1, TUP1; antigenic in murine systemic infection [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 46144 48277 + orf19.5436 46144 48277 1 46144 48277 46161 48251 UTP8 orf19.12891|IPF21700.1|IPF1136.2|Contig4-2896_0004|Contig4-2896_0005|orf6.8672|CA5787|CaO19.5436|CaO19.12891|IPF1136 Essential protein involved in tRNA export from the nucleus and ribosomal small subunit biogenesis; physically interacts with TAP-tagged Nop1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 48371 48843 + orf19.5433 48371 48843 1 48371 48843 48422 48775 orf19.12888|IPF21792.1|IPF1134.1|Contig4-2896_0007|orf6.8669|CA5786|FMP16|CaO19.5433|CaO19.12888|IPF1134 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 48912 49708 + orf19.5432 48912 49708 1 48912 49708 48915 49538 TPT1 orf19.12887|IPF21754.1|IPF1133.1|Contig4-2896_0008|orf6.8668|CA5785|CaO19.12887|CaO19.5432 tRNA 2'-phosphotransferase; enzyme of tRNA splicing; functionally complements viability of S. cerevisiae tpt1 null mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 50280 50646 - ntar_526 50280 50646 1 50646 50280 50474 50280 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 50894 52493 + orf19.5431 50894 52493 1 50894 52493 51706 52413 orf19.12886|IPF21750.1|IPF1129.1|Contig4-2896_0012|orf6.8667|CA5784|CaO19.5431|CaO19.12886|IPF1129 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 52545 53375 - orf19.5430 52545 53375 1 53375 52545 53342 52683 BUD21 orf19.12885|IPF21749.1|IPF1128.1|Contig4-2896_0013|orf6.8666|CA5783|CaO19.5430|CaO19.12885|IPF1128 Predicted ORF in Assemblies 19, 20 and 21; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 53429 55574 - orf19.5429 53429 55574 1 55574 53429 55492 53465 orf19.12884|IPF21704.1|IPF1127.2|Contig4-2896_0014|Contig4-2896_0016|orf6.8665|CA5782|CaO19.5429|CaO19.12884|IPF1127 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 55610 56898 + orf19.5428 55610 56898 1 55610 56898 55651 56463 orf19.12883|IPF21746.1|IPF1126.2|Contig4-2896_0018|orf6.8664|CA5781|CaO19.5428|ATX2|CaO19.12883|IPF1126 Predicted ORF in Assemblies 19, 20 and 21; clade-associated gene expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 56384 59403 - orf19.5426 56384 59403 1 59403 56384 59342 56493 orf19.12881|IPF21689.1|IPF1123.2|Contig4-2896_0020|orf6.8662|CA5780|CaO19.12881|CaO19.5426|IPF1123 Putative patatin-like phospholipase; macrophage-regulated gene; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 59640 62423 + orf19.5425 59640 62423 1 59640 62423 59837 62410 orf19.12880|IPF21691.1|IPF1121.2|Contig4-2864_0001|Contig4-2864_0002|orf6.8661|CA5779|CaO19.5425|CaO19.12880|IPF1121 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 59698 60243 - orf19.5424 59698 60243 1 60243 59698 60243 59698 IPF21766.1|IPF1120.2|orf6.8660|CaO19.12879|CaO19.5424 [NOT TRANSCRIBED?] ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 62513 63184 + orf19.5423 62513 63184 1 62513 63184 62513 63145 EST3 orf19.12878|orf6.8659|IPF21756.1|IPF1119.2|Contig4-2864_0003|CA5778|CaO19.12878|CaO19.5423|IPF1119 Telomerase subunit; required for telomere maintenance in vivo; separable roles in telomerase activity and processivity; not required for catalytic activity in vitro; related to mammalian Tpp1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 63235 63929 + orf19.5422 63235 63929 1 63235 63929 63282 63911 orf19.12877|IPF21761.1|IPF1118.1|Contig4-2864_0004|orf6.8658|CA5777|CaO19.12877|CaO19.5422|IPF1118 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 63928 65131 - orf19.5420 63928 65131 1 65131 63928 65094 63988 orf19.12875|IPF21739.1|IPF1116.1|Contig4-2864_0005|orf6.8656|CA5776|RML2|CaO19.12875|CaO19.5420 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 65350 66257 + orf19.5419 65350 66257 1 65350 66257 65437 66054 ATP5 orf19.12874|IPF21757.1|IPF1114.1|Contig4-2864_0006|orf6.8655|CA5775|CaO19.5419|CaO19.12874 Predicted ORF in Assemblies 19, 20 and 21; caspofungin repressed; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 66434 67995 + orf19.5418 66434 67995 1 66434 67995 66463 67896 orf19.12873|IPF21724.1|IPF1113.1|Contig4-2864_0007|orf6.8654|CA5774|CaO19.12873|CaO19.5418|IPF1113 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 67848 68968 - orf19.5417 67848 68968 1 68968 67848 68837 68046 DOT5 orf19.12872|IPF21747.1|IPF1111.1|Contig4-2864_0008|orf6.8653|CA5773|CaO19.5417|CaO19.12872 Alkaline downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 69858 71745 + orf19.5416 69858 71745 1 69858 71745 70068 71693 ESA1 orf19.12871|IPF21714.1|IPF1107.1|Contig4-2864_0013|orf6.8652|CA5772|CaO19.5416|CaO19.12871 Subunit of the NuA4 histone acetyltransferase complex [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 71532 72939 - orf19.5413 71532 72939 1 72939 71532 72883 71714 orf19.12868|IPF21740.1|IPF1104.1|Contig4-2864_0015|orf6.8649|CA5771|PRP46|CaO19.12868|CaO19.5413|IPF1104 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 72981 74119 + orf19.5412 72981 74119 1 72981 74119 73019 74104 orf19.12867|IPF21742.1|IPF1103.2|Contig4-2864_0016|orf6.8648|CA5770|CaO19.12867|CaO19.5412|IPF1103 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 74237 75020 + orf19.5411 74237 75020 1 74237 75020 74279 74863 orf19.12866|IPF21762.1|IPF1101.2|orf6.8647|CA5769|CaO19.5411|UBC12|CaO19.12866 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 74847 76531 - orf19.5410 74847 76531 1 76531 74847 76422 74962 orf19.12865|IPF21729.1|IPF1099.1|Contig4-2289_0002|orf6.8646|CA5768|CaO19.5410|PAC1|CaO19.12865 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 76909 77944 - orf19.5409 76909 77944 1 77944 76909 77889 77128 orf19.12864|IPF21748.1|IPF1098.1|Contig4-2289_0004|orf6.8645|CA5767|IST1|CaO19.12864|CaO19.5409|IPF1098 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 78054 80524 - orf19.5408 78054 80524 1 80524 78054 80270 78180 orf19.12863|IPF21701.1|IPF1097.1|Contig4-2289_0005|orf6.8644|CA5766|CaO19.5408|HRK1|CaO19.12863|IPF1097 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 81613 83085 - orf19.5407 81613 83085 1 83085 81613 83028 81718 SOF1 orf19.12862|IPF21734.1|IPF1095.1|Contig4-3071_0003|orf6.8643|CA5765|CaO19.12862|CaO19.5407 Predicted ORF in Assemblies 19, 20 and 21; transcription is upregulated in both intermediate and mature biofilms [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 83540 85863 - orf19.5406 83540 85863 1 85863 83540 85030 83705 orf19.12861|IPF21737.1|IPF20031.1|Contig4-3071_0005|Contig4-3071_0006|orf6.8642|CA5764|PSR1|CaO19.5406|CaO19.12861|IPF20031 Putative protein of unknown function, required for normal filamentous growth; mRNA binds to She3p and is localized to hyphal tips; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 87914 88757 + ntar_527 87914 88757 1 87914 88757 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 88863 90603 + orf19.5404 88863 90603 1 88863 90603 88912 90603 FLO9 orf19.12859|IPF21711.1|IPF1089.1|Contig4-3071_0011|orf6.8640|CA5763|IFF10|CaO19.12859|CaO19.5404|IFF10.5f|IFF10.5 Protein repressed during the mating process [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 90578 92662 + orf19.5401 90578 92662 1 90578 92662 90578 92647 orf19.12856|IPF21702.1|IPF1084.2|IPF1084.3|Contig4-3071_0012|orf6.8637|CA5762|CaO19.12856|CaO19.5401|IFF10.3f Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to toxic ergosterol analog; decreased transcription is observed upon fluphenazine treatment [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 90951 92676 + orf19.5402 90951 92676 1 90951 92676 90951 91517 IPF21765.1|IPF1081.2|orf6.8638 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 95652 97187 + orf19.5399 95652 97187 1 95652 97187 95652 97187 IFF11 orf19.12854|IPF21721.1|IPF1076.1|IPF21769.1|IPF1075.1|Contig4-3071_0014|orf6.8635|orf6.8636|CA5761|orf19.5400|CaO19.12854|CaO19.5399 Secreted protein required for normal cell wall structure and for virulence; member of the IFF family [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 97309 97668 - ntar_528 97309 97668 1 97668 97309 97668 97354 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 97601 98459 + orf19.5397 97601 98459 1 97601 98459 97647 98375 orf19.12852|IPF21753.1|IPF1072.1|Contig4-3071_0017|orf6.8633|CA5760|CaO19.12852|COG7|CaO19.5397|IPF1072 Predicted ORF in Assemblies 19, 20 and 21; decreased transcription is observed upon fluphenazine treatment [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 98248 98919 - orf19.5394.1 98248 98919 2 98919|98815 98878|98248 98888 98473 IPF21796.1|IPF1071.1|Contig4-3071_0018|CA5759|PET191|PET191.3 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 99188 103610 + orf19.5395 99188 103610 1 99188 103610 99338 103045 orf19.12850|IPF21795.1|IPF1069.1|Contig4-3071_0019|orf6.8631|CA5758|CaO19.12850|CaO19.5395|IPF1069 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 103789 105389 + orf19.5393 103789 105389 1 103789 105389 103831 105315 orf19.12848|IPF21727.1|IPF1067.1|Contig4-3071_0021|orf6.8629|CA5757|CaO19.12848|CaO19.5393|IPF1067 Putative cysteine sulfinate decarboxylase; transcription is positively regulated by Tbf1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 107125 108939 + orf19.5392 107125 108939 1 107125 108939 107369 108898 NGT1 orf19.12847|IPF21718.1|IPF1065.1|Contig4-3071_0022|orf6.8628|CA5756|CaO19.5392|CaO19.12847|IPF1065 N-acetylglucosamine (GlcNAc)-specific transporter; role in GlcNAc (but not serum) induced hyphal growth; localizes to plasma membrane; induced by GlcNAc, macrophage engulfment; 12 transmembrane, major facilitator superfamily [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 108606 108921 - ntar_529 108606 108921 1 108921 108606 108921 108670 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 109086 112898 + orf19.5391 109086 112898 1 109086 112898 109086 112745 orf19.12846|IPF21794.1|IPF1063.2|Contig4-3071_0027|Contig4-3071_0028|orf6.8627|CA5755|SAP130|CaO19.5391|CaO19.12846|IPF1063 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr3 112717 113604 - orf19.5390 112717 113604 1 113604 112717 113604 113161 orf19.12845|orf6.8625|IPF1059.2|IPF21770.1|IPF1060.2|Contig4-3071_0030|orf6.8626|CA5753|CaO19.12845|CaO19.5390|CA5754|IPF1060|FKH1|FKH2 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 113161 115834 - orf19.5389 113161 115834 2 115834|113660 113737|113161 115300 113161 FKH2 orf19.12844|orf6.8625|IPF21713.1|IPF1059.2|IPF1060.2|Contig4-3071_0032|orf6.8626|CA5753|CaO19.12844|CaO19.5389|CA5754|IPF1060|FKH1 Forkhead transcription factor; morphogenesis regulator; required for wild-type hyphal transcription, cell separation, and for virulence in cell culture; mutant lacks true hyphae, is constitutively pseudohyphal; upregulated in RHE model [label_first_exon=CGDmod label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 115885 117448 + ntar_530 115885 117448 1 115885 117448 116832 116993 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 116785 118322 - orf19.5388 116785 118322 1 118322 116785 118292 116949 SWD1 orf19.12843|IPF21735.1|IPF1055.2|Contig4-2666_0002|orf6.8624|CA5752|CaO19.5388|CaO19.12843|IPF1055 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 118487 122944 + orf19.5387 118487 122944 1 118487 122944 118538 122578 VPS8 orf19.12842|IPF21788.1|IPF11663.2|Contig4-2666_0003|Contig4-2666_0004|orf6.8623|CA5751|CaO19.5387|CaO19.12842 Protein described as a vacuolar sorting protein; downregulated upon adherence to polystyrene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr3 123198 127065 + orf19.5384 123198 127065 1 123198 127065 123508 126825 CHS8 orf19.12839|IPF21803.1|IPF11660.2|orf6.8620|CA5750|CHS3|CaO19.5384|CaO19.12839|CHS21 Chitin synthase required for synthesis of long-chitin fibrils; nonessential; 8 or 9 membrane spanning regions; mRNA present in yeast and hyphae; induced during cell wall regeneration; fungal-specific (no human or murine homologs) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 126884 127048 - ntar_531 126884 127048 1 127048 126884 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 127588 127853 + ntar_532 127588 127853 1 127588 127853 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 129854 130057 - ntar_533 129854 130057 1 130057 129854 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 130260 130813 - ntar_534 130260 130813 1 130813 130260 130581 130450 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 132900 136640 + orf19.5383 132900 136640 1 132900 136640 133121 135808 PMA1 orf19.12838|IPF21692.1|IPF8215.2|Contig4-2974_0020|orf6.4145|CA2300|CaO19.12838|CaO19.5383 Plasma membrane H(+)-ATPase; highly expressed, comprising 20-40% of total plasma membrane protein; abundance increases at stationary phase transition; fluconazole induced; caspofungin repressed; upregulated in RHE model [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 137170 140033 + orf19.5381 137170 140033 1 137170 140033 137633 139984 orf19.12836|IPF19392.2|IPF8222.2|Contig4-2974_0014|orf6.206|orf6.4143|CA2299|CaO19.5381|IPF8222 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 138357 140131 + orf19.5382 138357 140131 1 138357 140131 138416 139984 IPF8221.1|IPF18491.1|orf6.205|orf6.4144 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr3 140373 143047 + orf19.5380 140373 143047 1 140373 143047 140435 143020 LYS144 orf19.12835|IPF21694.1|IPF8224.2|Contig4-2974_0012|orf6.4142|CA2298|CaO19.12835|CaO19.5380|IPF8224 Putative transcription factor with zinc cluster DNA-binding motif; has similarity to S. cerevisiae Lys14p, which is a transcription factor involved in the regulation of lysine biosynthesis genes [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr3 143552 145180 + orf19.5379 143552 145180 1 143552 145180 143573 144982 ERG4 orf19.12834|IPF21722.1|IPF8225.1|Contig4-2974_0009|orf6.4141|CA2297|CaO19.5379|CaO19.12834 Protein described as similar to sterol C-24 reductase; shows Mob2p-dependent hyphal regulation; fluconazole-induced; caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 144934 145992 - orf19.5378 144934 145992 1 145992 144934 145926 145183 SCL1 orf19.12833|IPF21751.1|IPF8226.2|Contig4-2974_0008|orf6.4140|CA2296|CaO19.5378 Predicted ORF in Assemblies 19, 20 and 21; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 146194 147669 + orf19.5377 146194 147669 1 146194 147669 146267 147631 HOS2 orf19.12832|IPF16053.3|IPF21733.1|IPF8228.2|Contig4-2974_0006|orf6.1588|orf6.4139|CA2295|orf19.3067|CaO19.5377 Putative histone deacetylase; genetic evidence suggests that Set3p and Hos2p function together as a complex involved in regulation of white-opaque switching [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 147995 150803 + orf19.5376 147995 150803 1 147995 150803 148266 150701 orf19.12831|IPF16051.2|IPF21697.1|IPF28022.1|Contig4-2974_0004|orf6.1589|orf6.4138|CA0577|orf19.3068|CaO19.5376|CaO19.12831 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 152203 152592 - ntar_535 152203 152592 1 152592 152203 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 154030 154266 + ntar_536 154030 154266 1 154030 154266 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 154752 157787 + orf19.3071 154752 157787 1 154752 157787 155057 157741 MIH1 IPF19027.1|IPF9605.2|Contig4-2784_0008|Contig4-2784_0009|orf6.1170|orf6.1592|CA0578|orf19.1812|CaO19.3071|IPF9605 Putative protein phosphatase of the PTP family (tyrosine-specific), similar to S. cerevisiae Mih1p; mRNA binds to She3p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 157862 160841 - orf19.1288 157862 160841 1 160841 157862 160697 157977 FOX2 IPF19113.1|IPF9601.2|IPF18935.1|Contig4-2784_0005|orf6.882|orf6.1167|CA0347|orf19.3070.1|orf19.1809 Predicted 3-hydroxyacyl-CoA epimerase, required for fatty acid beta-oxidation; upregulated upon phagocytosis; transcription is regulated by Mig1p and by white-opaque switching; transcriptional activation by oleate requires Ctf1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 162669 165348 + orf19.1289 162669 165348 1 162669 165348 162858 165170 SCT1 IPF9596.1|IPF18377.2|Contig4-2784_0001|orf6.883|orf6.5315|CA0214|orf19.6154|CaO19.1289|SCT11 Putative glycerol-3-phosphate O-acyltransferase; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 165186 167707 - orf19.6155 165186 167707 1 167707 165186 167648 165336 CDC9|IPF9796.2|Contig4-2784_0016|orf6.5316|CA3145|CaO19.6155 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 167882 168479 - orf19.6156 167882 168479 1 168479 167882 168444 167947 IPF9797.2|Contig4-2310_0001|orf6.5317|CA3146|CaO19.6156|IPF9797 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 168663 171428 - orf19.6160 168663 171428 1 171428 168663 171341 168891 IPF9803.2|Contig4-2310_0003|orf6.5321|CA3147|CaO19.6160|IPF9803 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 172839 173927 + orf19.6163 172839 173927 1 172839 173927 173054 173689 CSE4 IPF9808.2|Contig4-2276_0004|orf6.5324|CA3148|CaO19.6163|IPF9808 Centromere-associated protein; essential; 4 Cse4p-containing nucleosomes, each containing 2 Cse4p molecules, bind to each centromere; similar to CENP-A (centromeric histone H3 variant) proteins; Cse4p and Mif2p colocalize at centromeres [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 174382 174708 + orf19.6164 174382 174708 1 174382 174708 174382 174708 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 175231 178601 + orf19.6165 175231 178601 1 175231 178601 175327 178317 KGD1 IPF19778.1|Contig4-2897_0018|orf6.5326|CA3149|CaO19.6165 Protein described as 2-oxoglutarate dehydrogenase; regulated by Efg1p under yeast-form but not hyphal growth conditions; transcription is upregulated in an RHE model of oral candidiasis; detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 178504 180833 - orf19.6166 178504 180833 1 180833 178504 180785 178635 IPF4035.1|Contig4-2897_0017|orf6.5327|CA3150|CaO19.6166|IPF4035 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 181011 182090 - orf19.6167 181011 182090 1 182090 181011 182020 181139 AYR1 IPF4033.2|Contig4-2897_0016|orf6.5328|CA3151|CaO19.6167|IPF4033 Protein described as putative oxidoreductase; transcriptionally induced by interaction with macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 182291 182860 + ntar_537 182291 182860 1 182291 182860 182560 182682 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 183128 185917 + orf19.6168 183128 185917 1 183128 185917 183131 185809 IPF4032.2|Contig4-2897_0010|Contig4-2897_0013|orf6.5329|CA3152|CaO19.6168|IPF4032 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr3 187467 188264 + orf19.6169 187467 188264 1 187467 188264 187467 188264 IPF4028.2|Contig4-2897_0004|orf6.5330|CA3153|AFF2|CaO19.6169|FRP2 Predicted ORF in Assemblies 19, 20 and 21; induced by Rgt1p [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 189211 190388 + orf19.2496 189211 190388 1 189211 190388 189367 190164 orf19.10032|FUN34|IPF24862.1|IPF4026.2|IPF18376.1|Contig4-2897_0002|orf6.6177|CA3813|CA3154|orf19.6169.2|AFF3|CaO19.2496|CaO19.10032|FRP1 Predicted ORF in Assemblies 19, 20 and 21; fluconazole-downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 191061 193051 + orf19.2498 191061 193051 1 191061 193051 191184 192869 orf19.10034|IPF24833.1|IPF4023.2|Contig4-2897_0001|orf6.6179|CA3814|CaO19.10034|SAN1|CaO19.2498|IPF4023 Predicted ORF in Assemblies 19, 20 and 21; oxidative stress-induced via Cap1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 192905 194231 - orf19.2499 192905 194231 1 194231 192905 194199 193075 orf19.10035|IPF24849.1|IPF4018.2|orf6.6180|CA3815|CPR7|CaO19.2499|CaO19.10035|CYP7 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 194314 195577 + orf19.2500 194314 195577 1 194314 195577 194339 195481 orf19.10036|IPF24848.1|IPF4017.2|Contig4-2453_0012|orf6.6181|CA3816|CaO19.10036|CaO19.2500|IPF4017 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 196084 196154 + tg(ucc)1 196084 196154 1 196084 196154 tG(UCC)1.2 tRNA-Gly predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 198258 201218 + orf19.2501 198258 201218 1 198258 201218 198712 201138 FLC1 orf19.10037|IPF17613.3|IPF4012.2|Contig4-2453_0003|orf6.2324|orf6.6182|CA1039|BOP1|CFP2|CaO19.2501|IPF4012 Protein involved in heme uptake; putative FAD transporter, similar to S. cerevisiae Flc1p; regulated by iron; macrophage-induced gene; mutant shows defect in filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 201350 202606 - orf19.2503 201350 202606 1 202606 201350 202606 201350 orf19.10039|IPF24842.1|IPF4010.2|Contig4-2453_0001|Contig4-2453_0002|orf6.2326|CA1040|CaO19.2503|CaO19.10039|IPF4010 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 202814 206550 + orf19.2504 202814 206550 1 202814 206550 202856 206488 BMS1 orf19.10040|IPF24887.1|IPF4009.2|Contig4-2895_0007|orf6.2327|CA1041|CaO19.10040|CaO19.2504 Predicted ORF in Assemblies 19, 20 and 21; mutation confers resistance to 5-fluorocytosine (5-FC); flucytosine induced; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 206590 206898 + orf19.2505 206590 206898 1 206590 206898 206590 206898 orf19.10041|IPF24893.1|IPF29103.1|orf6.2328|orf6.3910|CaO19.2505|CaO19.10041 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 209594 211739 + orf19.2506 209594 211739 1 209594 211739 209734 211527 orf19.10042|IPF16841.2|IPF18784.2|Contig4-2657_0017|orf6.2329|orf6.3911|CA1042|CaO19.2506|IPF18784|IPF18784.1 Predicted ORF in Assemblies 19, 20 and 21; opaque-specific transcription; Hog1p-downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 209667 209836 - ntar_538 209667 209836 1 209836 209667 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 211880 213638 + orf19.2507 211880 213638 1 211880 213638 211942 213396 ARP9 orf19.10043|IPF24839.1|IPF15652.2|Contig4-2657_0015|Contig4-2657_0016|orf6.3912|CA2137|CaO19.10043|CaO19.2507 Protein likely to be essential for growth, based on an insertional mutagenesis strategy; similar to S. cerevisiae Arp3p, which is a component of the Arp2/3 complex involved in actin-dependent processes [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 213616 215370 - orf19.2508 213616 215370 2 215370|214774 214847|213616 215370 213616 PRM9 orf19.10044|IPF24846.1|IPF15653.2|IPF15654.2|Contig4-2657_0014|orf6.3913|orf6.3914|CA2139|CaO19.2508|CaO19.10044|IPF15654|IPF15654.exon1 Protein not essential for viability; similar to S. cerevisiae Prm9p, which may bind to COPII coated vesicles [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 214843 215370 - orf19.2509 214843 215370 1 215370 214843 215370 214843 orf19.10045|IPF24867.1|IPF15654.2|Contig4-2657_0013|orf6.3914|CA2139|CaO19.10045|CaO19.2509|IPF15654|IPF15654.exon1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 216221 216950 + orf19.2509.1 216221 216950 1 216221 216950 216501 216710 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 216904 219972 - orf19.2510 216904 219972 1 219972 216904 219972 216982 orf19.10046|orf19.10047|IPF19665.1|IPF19664.1|IPF29081.1|IPF29083.1|Contig4-2657_0003|Contig4-2657_0004|Contig4-2657_0005|orf6.3915|orf6.3916|CA2140|CA2141|orf19.2511|IPF19665 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr3 220187 220841 + orf19.2511.1 220187 220841 1 220187 220841 220281 220571 MRPL33 IPF15872.2|IPF19409.2|Contig4-2657_0002|CA2142 ORF predicted by Annotation Working Group; increased expression observed in an ssr1 homozygous null mutant; transcription is upregulated in both intermediate and mature biofilms [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 221403 222323 + orf19.2511.2 221403 222323 1 221403 222323 221751 221975 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 222745 223728 + orf19.2512 222745 223728 1 222745 223728 222910 223569 orf19.10048|IPF12803.2|IPF29085.1|Contig4-1978_0003|orf6.3917|CA2143|CaO19.2512|CaO19.10048|IPF12803 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 223649 225820 - orf19.2513 223649 225820 1 225820 223649 225799 223649 orf19.10049|IPF24827.1|IPF12802.2|Contig4-1978_0004|Contig4-1978_0006|orf6.3918|CA2144|CaO19.2513|CaO19.10049|IPF12802 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chr3 225945 227325 + orf19.2514 225945 227325 1 225945 227325 226037 227098 orf19.10050|IPF24853.1|IPF12800.1|Contig4-2437_0007|orf6.3919|CA2145|CaO19.10050|CaO19.2514|IPF12800 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 227330 230120 - orf19.2515 227330 230120 1 230120 227330 230085 227431 orf19.10051|IPF24819.1|IPF12799.2|orf6.3920|CA2146|CaO19.10051|CaO19.2515|IPF12799 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr3 231284 232087 + orf19.2516 231284 232087 1 231284 232087 231365 232087 orf19.10052|IPF24860.1|IPF18533.1|orf6.3921|CA2147|IPF18533.5eoc|IPF18533 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr3 232356 232917 + ntar_539 232356 232917 1 232356 232917 232752 232892 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 232639 233900 - orf19.158 232639 233900 1 233900 232639 233668 232742 Contig4-1515_0003|orf6.136|APD1|CaO19.158|CA0019|IPF17799|IPF17799.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 235158 235455 - ntar_540 235158 235455 1 235455 235158 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 235239 235569 + ntar_541 235239 235569 1 235239 235569 235278 235469 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 235776 236229 - ntar_542 235776 236229 1 236229 235776 236062 235790 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 235898 238970 + orf19.3153 235898 238970 1 235898 238970 236577 238733 MSS4 orf19.10663|IPF24141.1|IPF15141.2|Contig4-2116_0004|orf6.1660|CA0623|CaO19.3153|MSS4.3f|MSS4.3 Phosphatidylinositol-4-phosphate 5-kinase; activity induced by phosphatidic acid (Pld1p product); macrophage/pseudohyphal-repressed; mRNA binds to She3p and is localized to buds of yeast-form cells and hyphal tips [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 238988 240816 + orf19.3154 238988 240816 1 238988 240816 239305 240759 orf19.10664|IPF312.3|IPF15139.2|Contig4-2595_0002|orf6.1661|orf6.2694|CA0624|CaO19.3154|IPF312 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 240837 244500 - orf19.3156 240837 244500 1 244500 240837 244246 240983 orf19.10665|IPF13504.2|IPF310.3|Contig4-2595_0003|Contig4-2595_0004|Contig4-2595_0005|orf6.1663|orf6.2693|CA1270|CaO19.3156|MDS1|IPF13504 Predicted ORF in Assemblies 19, 20 and 21; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 247708 248027 + ntar_543 247708 248027 1 247708 248027 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 248099 249793 - orf19.3158 248099 249793 1 249793 248099 249687 248260 orf19.10667|IPF19726.1|IPF13496.3|Contig4-1635_0002|orf6.2691|orf6.641|CA1269|RMD1|CaO19.3158|IPF19726 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 248132 248798 + ntar_544 248132 248798 1 248132 248798 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 249979 257674 + orf19.3159 249979 257674 1 249979 257674 250060 257565 UTP20 orf19.9300|orf19.9301|orf19.10668|IPF25622.1|IPF25609.1|IPF18641.1|IPF18640.1|IPF24144.1|IPF14693.2|orf6.3233|orf6.3232|orf6.2690|YBL004|CA1640|CA1639|CA1268|orf19.1732|orf19.1733|CaO19.10668|CaO19.3159|IPF14693 Protein likely to be essential for growth; similar to S. cerevisiae Utp20p, which is a putative snoRNA-binding protein; downregulated in core stress response; mutation confers resistance to 5-fluorocytosine (5-FC) and parnafungin [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr3 257604 258746 - orf19.1730 257604 258746 2 258746|258537 258612|257604 258651 257642 orf19.9298|orf19.9299|IPF25677.1|IPF25664.1|IPF9350.2|IPF9349.2|orf6.3235|orf6.3234|CA1642|CA1641|orf19.1731|NHP1.5f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 258865 260950 + orf19.1729 258865 260950 1 258865 260950 259892 260899 orf19.9297|IPF25625.1|IPF9347.2|Contig4-1881_0001|orf6.3236|CA1643|CaO19.9297|CaO19.1729|IPF9347 Putative transcription factor with zinc finger DNA-binding motif; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 260935 261567 - orf19.1728 260935 261567 1 261567 260935 261567 260935 orf19.9296|IPF25653.1|IPF9345.1|Contig4-1881_0002|orf6.3237|CA1644|CaO19.9296|CaO19.1728|IPF9345 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 261906 261994 - tr(ccu)1 261906 261994 2 261994|261941 261959|261906 tR(CCU)1.2 tRNA-Arg predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 263667 263895 - ntar_545 263667 263895 1 263895 263667 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 264035 264321 - ntar_546 264035 264321 1 264321 264035 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 264769 268784 + orf19.1727 264769 268784 1 264769 268784 264976 268611 PMC1 orf19.9295|IPF25700.1|IPF9340.1|Contig4-2981_0007|orf6.3238|CA1645|CaO19.1727|CaO19.9295 Vacuolar calcium P-type ATPase; transcription is regulated by calcineurin and fluconazole; mutant shows increased resistance to fluconazole or lithium, and increased sensitivity to calcium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 268997 269194 - ntar_547 268997 269194 1 269194 268997 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 269303 272073 - orf19.1725 269303 272073 1 272073 269303 271593 269416 orf19.9293|IPF8416.3|IPF9336.3|Contig4-2981_0008|orf6.3240|CA1646|CaO19.1725|IPF9336|IPF9336.3eoc|IPF9336.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr3 273912 274379 + orf19.1724 273912 274379 1 273912 274379 273912 274379 orf19.9292|IPF25671.1|IPF8408.1|Contig4-2981_0013|orf6.4836|CA2794|CaO19.9292|CaO19.1724|IPF8408 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide in yhb1 mutant [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 274393 275347 + orf19.1723 274393 275347 1 274393 275347 274599 275267 orf19.9291|IPF25651.1|IPF8407.1|Contig4-2981_0015|orf6.4837|CA2795|CaO19.9291|CaO19.1723|IPF8407 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 275446 275862 + orf19.1722 275446 275862 1 275446 275862 275446 275862 orf19.9290|IPF25679.1|IPF29361.1|orf6.4838|CaO19.1722|CaO19.9290 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 275637 276942 - orf19.1721 275637 276942 1 276942 275637 276550 275705 NCE103 orf19.9289|IPF25642.1|IPF8405.1|Contig4-2981_0017|orf6.4839|CA2796|CaO19.9289|CaO19.1721|IPF8405 Carbonic anhydrase involved in the conversion of carbon dioxide to bicarbonate; essential for pathogenesis in host niches with limited CO2, wild-type white-opaque switching; biofilm induced; activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 277473 280213 + orf19.1720 277473 280213 1 277473 280213 277547 280141 orf19.9288|IPF25592.1|IPF8404.1|Contig4-2981_0018|orf6.4840|CA2797|CaO19.1720|CaO19.9288|IPF8404 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr3 280282 282435 - orf19.1719 280282 282435 1 282435 280282 282178 280484 SGA1 orf19.9287|IPF25618.1|IPF8402.2|Contig4-2981_0019|orf6.4841|CA2798|CaO19.9287|CaO19.1719|IPF8402 Putative glucoamylase; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr3 285283 288369 + orf19.1718 285283 288369 1 285283 288369 285487 288234 ZCF8|orf19.9286|IPF25589.1|IPF19769.1|orf6.4842|CA2799|CaO19.1718|CaO19.9286|IPF19769 Predicted zinc-finger protein of unknown function; decreased transcription is observed upon fluphenazine treatment [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr3 288537 290253 + orf19.1717 288537 290253 1 288537 290253 288792 290177 orf19.9285|orf6.4843|IPF25627.1|IPF11366.2|Contig4-2578_0002|CA2800|CaO19.1717|CaO19.9285|IPF11366 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr3 290190 291260 - orf19.1716 290190 291260 1 291260 290190 291144 290332 URA3 orf19.9284|IPF25647.1|IPF11364.1|Contig4-2578_0003|orf6.4844|CA2801|CaO19.9284|CaO19.1716 Orotidine-5'-phosphate decarboxylase, enzyme of pyrimidine biosynthesis; gene used as a molecular genetic marker, but decreased expression when integrated at ectopic chromosomal locations can cause defects in hyphal growth and virulence [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 291469 293484 - orf19.1715 291469 293484 1 293484 291469 293370 291580 IRO1 orf19.9283|orf6.4843|IPF11363.1|IPF29338.1|Contig4-2578_0004|Contig4-2578_0006|orf6.4845|CA2802|CaO19.9283|CaO19.1715|IPF11363 Putative transcription factor; role in iron utilization, pathogenesis; both IRO1 and adjacent URA3 are mutated in strain CAI4; suppresses S. cerevisiae aft1 mutant low-iron growth defect; hyphal-induced; reports differ about iron regulation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 294259 295610 - orf19.1714 294259 295610 1 295610 294259 295376 294453 PGA44 orf19.9282|IPF25662.1|IPF14081.2|orf6.3113|orf6.4847|orf6.4846|CA1553|CaO19.1714|IPF14081 Putative GPI-anchored protein of unknown function [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 296758 300499 - orf19.1712 296758 300499 1 300499 296758 300272 296889 GEA2 orf19.9279|orf19.9280|orf6.3114|IPF25656.1|IPF25714.1|IPF14074.1|IPF14077.1|Contig4-2180_0007|orf6.3115|CA1555|CA1554|orf19.1713|GEA2.5f Protein described as an ARF GTP/GDP exchange factor; transcriptionally regulated by iron; expression greater in low iron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 301391 302734 + orf19.1711 301391 302734 1 301391 302734 301514 302701 END3 orf19.9278|IPF25635.1|IPF15676.2|orf6.3116|CA1556|CaO19.9278|CaO19.1711 Regulated by Gcn4p; induced in response to amino acid starvation (3-aminotriazole treatment) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 302703 303891 - orf19.1710 302703 303891 1 303891 302703 303621 302782 orf19.9277|IPF25643.1|IPF15677.2|Contig4-2424_0009|orf6.3117|CA1557|CaO19.1710|CaO19.9277|IPF15677 Protein described as NADH-ubiquinone oxidoreductase; identified in detergent-resistant membrane fraction (possible lipid raft component); predicted N-terminal acetylation; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 304032 304727 + ntar_548 304032 304727 1 304032 304727 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 304676 305386 - orf19.1709 304676 305386 1 305386 304676 305176 304793 orf19.9276|IPF25694.1|IPF15679.2|Contig4-2424_0007|orf6.3118|CA1558|CaO19.1709|POX181|CaO19.9276|IPF15679 Predicted ORF in Assemblies 19, 20 and 21; alkaline downregulated; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 306698 307756 + orf19.1708 306698 307756 1 306698 307756 306822 307481 orf19.9275|IPF25649.1|IPF16533.2|Contig4-2424_0002|orf6.3119|CA1559|CaO19.9275|CaO19.1708|IPF16533 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 307468 307957 - orf19.1707 307468 307957 1 307957 307468 307957 307640 orf19.9274|IPF25708.1|IPF16535.2|Contig4-2424_0001|orf6.3120|CaO19.1707|CaO19.9274 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 307973 311242 - orf19.1706 307973 311242 1 311242 307973 311242 307973 MET18 orf19.9273|IPF25707.1|IPF16088.2|Contig4-2424_0011|orf6.3121|CA1560|CaO19.1706|CaO19.9273 Predicted ORF in Assemblies 19, 20 and 21; Plc1p-regulated [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 311312 311516 + ntar_549 311312 311516 1 311312 311516 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 311480 312988 - orf19.1704 311480 312988 1 312988 311480 312779 311547 FOX3 orf19.9271|IPF17552.3|IPF16087.1|POT1-1|Contig4-2869_0003|orf6.3123|CA1561|POT2|CaO19.9271|CaO19.1704|POT12|CA1505|POT1|IPF17552.2 Putative peroxisomal 3-oxoacyl CoA thiolase; expression is regulated upon white-opaque switching [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 313769 314526 + ntar_550 313769 314526 1 313769 314526 314109 314267 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 314540 314705 - ntar_551 314540 314705 1 314705 314540 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 314798 316003 + orf19.1702 314798 316003 2 314798|315301 315187|316003 315173 315813 ARF3 orf19.9269|IPF25666.1|IPF13664.2|Contig4-2869_0006|orf6.3043|CA1504|CaO19.1702|CaO19.9269 Transcription is filament induced; Tup1p regulated (see Locus History Note for Assembly 19 correction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 315925 317060 - orf19.1701 315925 317060 1 317060 315925 316838 316047 RKI1 orf19.9268|IPF13663.2|IPF29351.1|Contig4-2869_0008|orf6.3042|CA1503|CaO19.9268|CaO19.1701 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr3 317350 318197 + orf19.1700 317350 318197 1 317350 318197 317436 317996 RPS7A orf19.9267|IPF13662.1|IPF29352.1|Contig4-2869_0009|orf6.3041|CA1502|CaO19.1700|RPS7 Predicted ribosomal protein; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 318153 320256 - orf19.1699 318153 320256 1 320256 318153 320137 318275 BZZ1 orf19.9266|IPF25611.1|IPF13661.3|Contig4-2869_0011|orf6.3040|orf6.374|CA0060|CaO19.1699|IPF13661|IPF13661.2 Protein similar to S. cerevisiae Bzz1p, which is an SH3 domain protein involved in the regulation of actin polymerization [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 320416 322953 + orf19.1698 320416 322953 1 320416 322953 320920 322818 orf19.9265|IPF13217.2|IPF13660.3|Contig4-2869_0012|orf6.3039|orf6.375|CA1501|CaO19.1698|IPF13217 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 322810 324061 - orf19.1697 322810 324061 1 324061 322810 324006 322945 orf19.9264|IPF25640.1|IPF13221.2|Contig4-2869_0013|orf6.3038|CA1500|CaO19.9264|CaO19.1697|IPF13221 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 324236 332768 - orf19.1693 324236 332768 1 332768 324236 332768 324276 CAS4 orf19.9261|IPF25646.1|IPF29342.1|IPF6521.3|Contig4-2861_0008|Contig4-2861_0009|Contig4-2861_0010|Contig4-2869_0015|orf6.3035|orf6.4146|CA2301|CA6262|orf19.1694|TAO3|PAG1|TAO3.5f Protein of RAM cell wall integrity signaling network; role in cell separation, azole sensitivity; required for hyphal growth; insertion mutation near 3' end of gene causes increase in caspofungin sensitivity; pheromone/hyphal induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 333015 333238 + ntar_552 333015 333238 1 333015 333238 333015 333173 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 333609 333857 - ntar_553 333609 333857 1 333857 333609 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 335658 336659 + orf19.1691 335658 336659 1 335658 336659 335873 336460 orf19.9259|IPF19200.1|IPF6518.1|Contig4-2909_0014|orf6.4148|orf6.653|CA2302|CaO19.9259|CaO19.1691|IPF6518 Predicted ORF in Assemblies 19, 20 and 21; fluconazole-induced; filament induced; Hog1p-induced; regulated by Nrg1p, Tup1p; increased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 336642 338572 - orf19.1690 336642 338572 1 338572 336642 338325 336919 TOS1 orf19.9258|IPF25628.1|IPF6517.2|Contig4-2909_0012|orf6.4149|CA2303|CaO19.1690 Protein described as similar to alpha agglutinin anchor subunit; exogenously expressed protein is a substrate for Kex2p processing in vitro; fluconazole-induced; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 342606 345175 + orf19.1687 342606 345175 1 342606 345175 342685 344988 orf19.9255|IPF25600.1|IPF6512.1|Contig4-2909_0003|orf6.4152|CA2304|CaO19.9255|PRP43|CaO19.1687 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 345387 347222 + orf19.1686 345387 347222 1 345387 347222 345434 347143 orf19.9254|IPF25619.1|IPF6511.1|Contig4-2909_0002|orf6.4153|CA2305|MPA43|CaO19.9254|CaO19.1686 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 347644 349205 + orf19.1685 347644 349205 1 347644 349205 347789 349138 ZCF7|IPF6510.2|orf6.4154|CA2306|CaO19.1685|IPF6510 Predicted zinc-finger protein of unknown function [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 349227 351284 + orf19.1684 349227 351284 1 349227 351284 349260 350942 orf19.9253|IPF11676.2|IPF29339.1|Contig4-2363_0007|orf6.4155|orf6.1329|CA2307|CaO19.1684|IPF18488|IPF18488.5eoc|IPF18488.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 351680 353158 + orf19.1683 351680 353158 1 351680 353158 351846 352928 PPH21 orf19.9252|IPF11679.2|IPF11680.3|Contig4-2363_0004|orf6.1330|orf6.890|CA0425|CaO19.1683 Putative protein phosphatase of the Type 2A-related family (serine/threonine-specific), similar to S. cerevisiae Pph21p; caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 353043 353273 - ntar_554 353043 353273 1 353273 353043 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 353526 354849 + orf19.1682 353526 354849 1 353526 354849 353615 354775 orf19.9251|IPF25637.1|IPF11681.2|Contig4-2363_0002|orf6.889|CA0216|CaO19.1682|CaO19.9251|IPF11681 Predicted ORF in Assemblies 19, 20 and 21; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 354991 355619 + orf19.1681 354991 355619 1 354991 355619 355042 355602 orf19.9250|IPF25657.1|IPF11682.3|Contig4-2363_0001|Contig4-2527_0013|orf6.2003|orf6.888|CA0839|CaO19.1681|IPF12492|IPF12492.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 355873 358169 + orf19.1680 355873 358169 2 355873|356066 355988|358169 355986 357916 orf19.9249|IPF12493.1|IPF29347.1|IPF29353.1|Contig4-2527_0012|orf6.2002|CA0838|TFP1|TFP1.5f|orf19.1679.2 Predicted ORF in Assemblies 19, 20 and 21; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 358214 359143 - orf19.1679 358214 359143 1 359143 358214 359143 358214 orf19.9248|IPF12495.1|IPF29348.1|Contig4-2527_0011|orf6.2001|CA0836|CaO19.1679|IPF12495|CA0837|IPF12495.3f|IPF12494.1|IPF12495.5f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 359970 360570 + orf19.1678 359970 360570 1 359970 360570 360220 360570 orf19.9247|Contig4-2527_0008|orf6.2000|CaO19.9247|CaO19.1678 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 360020 362392 - ntar_555 360020 362392 1 362392 360020 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 360649 361602 + orf19.1677 360649 361602 1 360649 361602 360649 361446 orf19.9246|IPF25645.1|IPF12499.2|Contig4-2527_0007|orf6.1999|CA0834|CaO19.9246|CaO19.1677|IPF12498.3f Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 362653 364078 - orf19.1676 362653 364078 1 364078 362653 363851 362745 orf19.9245|IPF12502.2|IPF12501.2|IPF29330.1|IPF29350.1|Contig4-2527_0003|Contig4-2527_0005|orf6.1998|CA0833|IPF12501 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 362801 363873 + ntar_556 362801 363873 1 362801 363873 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 365050 366730 + orf19.1675 365050 366730 1 365050 366730 365360 366562 orf19.9244|IPF14225.2|IPF29346.1|Contig4-2335_0007|orf6.1997|CA0832|CaO19.1675|CaO19.9244|IPF14225 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 366580 366890 - ntar_557 366580 366890 1 366890 366580 366738 366580 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 367126 369811 + orf19.1674 367126 369811 1 367126 369811 367387 369645 CDC53 orf19.9243|IPF25604.1|IPF14223.1|Contig4-2335_0001|orf6.1083|CA0297|CaO19.1674|CaO19.9243 Cullin, a scaffold subunit of the SCF ubiquitin-ligase complexes; depletion leads to increased filamentous growth and premature cell death [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 369744 371795 - orf19.1673 369744 371795 1 371795 369744 371639 369945 PPT1 orf19.9242|orf6.1084|IPF25613.1|IPF14222.3|Contig4-2335_0002|CA0298|CaO19.1673|IPF14222.2 Protein described as serine/threonine phosphatase; transcriptionally regulated by iron; expression greater in high iron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 372104 376003 - orf19.1672 372104 376003 1 376003 372104 375911 372246 orf19.9241|IPF8079.2|IPF29375.1|Contig4-3069_0031|orf6.1640|CA0606|COP1|CaO19.1672 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 376362 378084 - orf19.1671 376362 378084 1 378084 376362 377817 376405 UTR2 orf19.9240|orf6.1639|IPF8080.2|IPF29345.1|Contig4-3069_0027|CA0605|CSF4|CaO19.9240|CaO19.1671 GPI anchored cell wall putative glycosidase; role in adhesion; required for hyphal growth on Spider (not serum) medium; chitin-binding, glycosyl hydrolase domains; induced during cell wall regeneration; mRNA detected in yeast-form cells [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 379539 380234 - ntar_558 379539 380234 1 380234 379539 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 381965 384940 - orf19.1670 381965 384940 1 384940 381965 384874 382037 BRO1 orf19.9239|IPF25590.1|IPF8087.2|Contig4-3069_0020|orf6.5745|CA3475|CaO19.9239|CaO19.1670 Protein involved in transport from multivesicular body to vacuole; similar to S. cerevisiae Bro1p, which is a class E vacuolar protein sorting (VPS) factor; not involved in RIM101 pathway; macrophage/pseudohyphal-repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr3 385588 388252 + orf19.1669 385588 388252 1 385588 388252 385664 388051 AFG3 orf19.9238|IPF25597.1|IPF8090.2|Contig4-3069_0019|orf6.5744|CA3474|CaO19.9238|CaO19.1669 Protein likely to be essential for growth, based on an insertional mutagenesis strategy; similar to S. cerevisiae Afg3p, which is a subunit of the mitochondrial inner membrane m-AAA protease [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 388123 390117 - orf19.1668 388123 390117 1 390117 388123 390091 388220 orf19.9237|IPF25608.1|IPF6305.2|Contig4-3069_0018|orf6.5743|CA3473|CaO19.1668|CaO19.9237|IPF6305|IPF6305.exon1 Predicted ORF in Assemblies 19, 20 and 21; decreased expression observed in an ssr1 homozygous null mutant; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 390175 390687 - orf19.1667.1 390175 390687 1 390687 390175 390580 390314 IPF25704.1|IPF6306.1|Contig4-3069_0016|CA3472|IPF6306|IPF6305.exon2 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 390690 394545 - orf19.1667 390690 394545 1 394545 390690 394545 390793 orf19.9236|IPF25699.1|IPF6308.2|Contig4-3069_0013|Contig4-3069_0015|orf6.5742|CA3471|CaO19.9236|CaO19.1667|IPF6308 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr3 395033 397351 - orf19.1666 395033 397351 1 397351 395033 396749 395154 orf19.9235|IPF25623.1|IPF6310.1|Contig4-3069_0012|orf6.5741|CA3470|CaO19.1666|CaO19.9235|IPF6310 Predicted ORF in Assemblies 19, 20 and 21; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 398727 401199 - orf19.1665 398727 401199 1 401199 398727 400423 399128 MNT1 orf19.9234|KTR1|IPF25633.1|IPF6315.2|Contig4-3069_0008|Contig4-3069_0009|orf6.5740|CA3469|CaO19.9234|CaO19.1665 Alpha-1,2-mannosyl transferase; adds second mannose during cell-wall mannoprotein biosynthesis; required for wild-type virulence and adherence to epithelial cells; predicted type II membrane protein of Golgi; fungal-specific [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 402538 405155 + orf19.1664 402538 405155 1 402538 405155 402555 405155 orf19.9233|IPF25593.1|IPF6318.2|Contig4-3069_0005|orf6.5739|CA3468|CaO19.9233|BGL98|CaO19.1664|IPF6318 Predicted ORF in Assemblies 19, 20 and 21; decreased expression observed in an ssr1 homozygous null mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chr3 405140 407180 - orf19.1663 405140 407180 1 407180 405140 406706 405321 MNT2 orf19.9232|IPF25631.1|IPF6319.2|Contig4-3069_0003|orf6.5738|KRE2|CA3467|CaO19.9232|CaO19.1663 Alpha-1,2-mannosyl transferase; adds third mannose during cell-wall mannoprotein biosynthesis; partially redundant with Mnt1p; role in adherence and virulence; expressed in yeast-form and hyphal cells; fungal-specific [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 408051 408124 - tv(aac)2 408051 408124 1 408124 408051 tV(AAC)2.2 tRNA-Val predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 408998 410212 + orf19.1662 408998 410212 1 408998 410212 409039 410094 orf19.9231|IPF25644.1|IPF12526.2|Contig4-2479_0010|orf6.5737|CA3466|CaO19.9231|MRP1|CaO19.1662|MRP1.5f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 410189 412017 - orf19.1661 410189 412017 1 412017 410189 411950 410328 DBP5 orf19.9230|IPF25616.1|IPF12528.2|Contig4-2479_0009|orf6.5736|CA3464|CaO19.9230|CaO19.1661 Protein described as RNA helicase; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 412146 412220 - tk(uuu)1 412146 412220 1 412220 412146 tK(UUU)1.2 tRNA-Lys predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 412538 414587 + orf19.1659 412538 414587 1 412538 414587 412614 414377 ALG8 orf19.9228|IPF25617.1|IPF12530.2|Contig4-2479_0006|orf6.5734|CA3463|CaO19.1659 Putative glucosyltransferase involved in cell wall mannan biosynthesis; transcription is elevated in nik1 and sln1 homozygous null mutants, but not in the chk1 null mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 414493 416815 - orf19.1658 414493 416815 2 416815|415793 416350|414493 416642 414755 orf19.9226|orf19.9227|IPF19685.1|IPF29349.1|Contig4-1784_0004|Contig4-2479_0002|Contig4-2479_0003|orf6.833|orf6.834|CA0198|orf19.1657|IPF19685 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 418369 420327 - orf19.1656 418369 420327 1 420327 418369 420268 418472 orf19.9225|IPF25614.1|IPF13675.2|Contig4-2722_0003|orf6.1219|CA0369|CaO19.9225|CaO19.1656|IPF13675 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr3 422298 422987 - orf19.1655.3 422298 422987 1 422987 422298 422878 422711 IPF18656.2|IPF13678.2|Contig4-1759_0003|CA0370|IPF13678 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 423245 423446 + ntar_559 423245 423446 1 423245 423446 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 423775 423889 - ty(gua)2 423775 423889 2 423889|423810 423853|423775 tY(GUA)2.2 tRNA-Tyr predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 425276 427659 + orf19.1655 425276 427659 1 425276 427659 425332 427506 PXP2 orf19.9224|IPF25599.1|IPF13474.2|POX1-1|Contig4-2710_0004|orf6.3140|CA1574|CaO19.1655|POX102|CaO19.9224 Putative acyl-CoA oxidase; enzyme of fatty acid beta-oxidation; induced during macrophage infection; expression is opaque specific; has putative peroxisome targeting signal [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 427558 428290 - orf19.1654 427558 428290 1 428290 427558 428219 427632 orf19.9223|IPF25652.1|IPF20085.1|Contig4-2710_0007|orf6.3139|CaO19.1654|CaO19.9223 Predicted ORF in Assemblies 19, 20 and 21; increased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 428373 429291 - orf19.1653 428373 429291 1 429291 428373 429148 428558 orf19.9222|IPF25655.1|IPF15087.2|Contig4-2710_0009|orf6.3138|CA1573|CaO19.1653|CaO19.9222|IPF15087 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 428560 428782 + ntar_560 428560 428782 1 428560 428782 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 429396 429923 + ntar_561 429396 429923 1 429396 429923 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 429439 431893 - orf19.1652 429439 431893 1 431893 429439 431734 429605 POX1-3 orf19.9221|IPF15088.2|IPF15794.2|POX1|POX99|Contig4-2710_0011|Contig4-2710_0012|orf6.3137|orf6.828|CA1572|POX4|POX104|CaO19.1652 Predicted acyl-CoA oxidase; farnesol regulated; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 433092 434981 - orf19.1651 433092 434981 1 434981 433092 434322 433795 orf19.9220|IPF25661.1|IPF15799.1|Contig4-1923_0003|orf6.827|CA0196|CaO19.9220|CaO19.1651|IPF15799 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr3 434378 435802 + ntar_562 434378 435802 1 434378 435802 434688 434834 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 435563 436165 - orf19.1650 435563 436165 1 436165 435563 436145 435840 orf19.9219|IPF15801.2|IPF19134.2|Contig4-1923_0001|orf6.2330|orf6.826|CA1043|CaO19.1650|TOM6 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr3 436164 437541 + orf19.1649 436164 437541 1 436164 437541 436241 437485 RNA1 orf19.9218|IPF11621.2|IPF15802.3|orf6.2331|orf6.825|CA1044|CaO19.1649 Predicted ORF in Assemblies 19, 20 and 21; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 437607 441742 + orf19.1648 437607 441742 1 437607 441742 437607 441605 RAD50 orf19.9217|IPF25689.1|IPF11620.2|orf6.2332|CA1045|CaO19.9217|CaO19.1648|IPF11620 Protein described as DNA double-strand break repair factor; involved in response to oxidative stress and drug resistance [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 441625 442732 - orf19.1647 441625 442732 2 442732|442416 442499|441625 442732 441625 orf19.9216|IPF25648.1|IPF11617.2|Contig4-2368_0002|orf6.2333|CA1046|CaO19.9216|CaO19.1647|IPF11617 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 442914 445602 + orf19.1646 442914 445602 1 442914 445602 442966 445503 orf19.9215|IPF11615.2|IPF29332.1|Contig4-2368_0004|orf6.2334|CA1047|MRD1|CaO19.1646|IPF11615|CA3995|IPF11615.3eoc|IPF10438.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr3 445660 446838 + orf19.1643 445660 446838 1 445660 446838 445678 446661 orf19.9211|IPF25663.1|IPF10440.2|Contig4-2347_0004|orf6.2338|orf6.6429|CA3996|CaO19.1643|PCP1|IPF10440|IPF10440.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 446661 447479 - orf19.1642 446661 447479 1 447479 446661 447344 446724 orf19.9209|IPF25650.1|IPF10442.1|Contig4-2347_0006|orf6.6430|CA3997|CaO19.1642|LOC1|CaO19.9209 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 447623 447716 - te(uuc)2 447623 447716 2 447716|447657 447680|447623 tE(UUC)2.2 tRNA-Glu predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 448248 449519 + orf19.1641 448248 449519 1 448248 449519 448248 449519 orf19.9208|IPF19209.2|IPF10443.2|Contig4-2347_0008|orf6.623|orf6.6431|CA3998|CaO19.1641|FAP99|IPF10443 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr3 449569 450735 - orf19.1639 449569 450735 1 450735 449569 450735 449569 orf19.9207|IPF10444.2|IPF18268.1|IPF15933.2|Contig4-2347_0009|orf6.624|orf6.6432|orf6.6433|CA0136|CA6260|orf19.1640|IFH1|IFH1.5f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 451463 454178 + orf19.1638 451463 454178 1 451463 454178 451512 454097 orf19.9206|IPF10446.3|IPF29331.1|Contig4-2997_0003|Contig4-2997_0005|orf6.625|orf6.6434|CA0137|SEC232|CaO19.1638|SEC233|IPF10446.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 454004 455112 - orf19.1637 454004 455112 1 455112 454004 455047 454106 orf19.9205|IPF25641.1|IPF10447.2|Contig4-2997_0006|orf6.6435|CA3999|CaO19.1637|IPF10447 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 455988 457597 + orf19.1636 455988 457597 1 455988 457597 456168 457550 STE50 orf19.9204|IPF25630.1|IPF4262.2|Contig4-2997_0011|orf6.6436|CA4000|CaO19.9204|CaO19.1636|IPF4262 Protein with sterile alpha motif (SAM) and Ras-associated domain (RAD); similar to S. cerevisiae Rad50p, which is involved in signal transduction via interaction with and regulation of MAPKKK [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 456454 457560 - ntar_563 456454 457560 1 457560 456454 456901 456764 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 457816 458929 + orf19.1635 457816 458929 1 457816 458929 457878 458375 RPL12 orf19.9203|IPF25668.1|IPF4260.2|RPL15B|Contig4-2997_0012|orf6.6437|CA4001|CaO19.9203|CaO19.1635 Predicted ribosomal protein; downregulated in the presence of human whole blood or polymorphonuclear (PMN) cells; genes encoding cytoplasmic ribosomal subunits are downregulated upon phagocytosis by murine macrophage; Tbf1p-activated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 459069 460704 + orf19.1634 459069 460704 2 459069|459472 459401|460704 459386 460586 orf19.9202|IPF25639.1|IPF4258.2|Contig4-2997_0015|orf6.6438|CA4002|IPF4258 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 460896 463271 + orf19.1633 460896 463271 1 460896 463271 460975 463206 UTP4 orf19.9201|IPF25598.1|IPF4257.2|Contig4-2997_0017|orf6.6439|CA4003|CaO19.9201|CaO19.1633|IPF4257 Predicted ORF in Assemblies 19, 20 and 21; physically interacts with TAP-tagged Nop1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 463213 464758 - orf19.1632 463213 464758 1 464758 463213 464495 463278 orf19.9200|IPF25634.1|IPF4256.2|Contig4-2997_0018|orf6.6440|CA4004|CaO19.1632|CaO19.9200|IPF4256 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 464890 466371 - orf19.1631 464890 466371 1 466371 464890 466246 465116 ERG6 orf19.9199|IPF25638.1|IPF4255.2|Contig4-2997_0019|orf6.6441|CA4005|CaO19.9199|CaO19.1631 Delta(24)-sterol C-methyltransferase, converts zymosterol to fecosterol in ergosterol biosynthesis by methylating position C-24; mutation confers nystatin resistance; fluconazole-induced; transcription increased in azole-resistant strain [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 467156 469919 - orf19.1630 467156 469919 3 469919|469557|469422 469710|469513|467156 469713 467189 orf19.9198|IPF25601.1|IPF4253.1|Contig4-2997_0020|orf6.6442|CA4006|IPF4253 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 470339 472130 - orf19.1628 470339 472130 1 472130 470339 472087 470534 LAP41 orf19.9196|IPF25621.1|IPF4250.1|Contig4-2997_0024|orf6.6444|CA4007|CaO19.9196|LAP4|CaO19.1628 Protein not essential for viability; similar to S. cerevisiae Lap4p, which is a vacuolar aminopeptidase; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 472242 473562 - orf19.1626 472242 473562 1 473562 472242 473525 472386 orf19.9194|IPF25636.1|IPF4248.2|Contig4-2997_0025|orf6.6446|CA4008|CaO19.1626|DYS1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 473716 474552 - orf19.1625 473716 474552 1 474552 473716 474401 473979 orf19.9193|IPF25669.1|IPF4247.1|Contig4-2997_0026|orf6.6447|CA4009|CaO19.1625|IPF4247 Predicted ORF in Assemblies 19, 20 and 21; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 474576 475550 + orf19.1624.1 474576 475550 1 474576 475550 474686 474862 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 474772 477473 - orf19.1624 474772 477473 2 477473|477291 477372|474772 477390 474905 orf19.9192|IPF17282.3|IPF4245.2|orf6.6448|orf6.786|CA4010|MAK10.3f|MAK10.3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 478729 480673 + orf19.1623 478729 480673 1 478729 480673 479016 480515 CAP1 orf19.9191|IPF4242.2|IPF29344.1|Contig4-2798_0003|orf6.6449|orf6.787|CA0183|CaO19.1623 Transcription factor, AP-1 family; role in oxidative stress response and resistance, multidrug resistance; oxidative stress regulates nuclear localization; partially complements S. cerevisiae yap1 mutation; human neutrophil-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 480614 484643 - orf19.1622 480614 484643 1 484643 480614 484531 480752 YCG1 orf19.9190|IPF25696.1|IPF4240.2|Contig4-2798_0005|orf6.6450|orf6.788|CA4011|CaO19.1622|IPF4240 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr3 484819 486846 - orf19.1621 484819 486846 1 486846 484819 486481 484973 GPA2 orf19.9189|IPF25624.1|IPF4239.2|Contig4-2798_0009|orf6.6451|CA4012|CAG99|CaO19.9189|CaO19.1621 G-protein alpha subunit; regulates filamentous growth; reports differ on a role in cAMP-mediated glucose signaling, cAMP-PKA pathway, MAP kinase cascade; Gpr1p C terminus binds Gpa2p; regulates HWP1 and ECE1 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 488508 488996 - orf19.1620 488508 488996 1 488996 488508 488996 488508 orf19.9188|IPF25665.1|IPF4234.2|Contig4-2798_0014|orf6.6452|CA4013|CaO19.9188|CaO19.1620|IPF4234 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 489036 491018 - orf19.1619 489036 491018 1 491018 489036 490945 489185 orf19.9187|IPF25612.1|IPF4233.2|Contig4-2798_0016|orf6.6453|CA4014|CTK1|CaO19.1619|CaO19.9187 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 491325 491639 - ntar_564 491325 491639 1 491639 491325 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 492256 493049 + orf19.1618.1 492256 493049 1 492256 493049 492585 492809 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 493070 495775 - orf19.1618 493070 495775 1 495775 493070 495614 493473 GFA1 orf19.9186|IPF17771.2|IPF12267.2|Contig4-2597_0003|orf6.1027|orf6.6454|CA4016|CaO19.1618 Glucosamine-6-phosphate synthase; enzyme of chitin/hexosamine biosynthesis; homotetrameric; inhibited by UDP-GlcNAc, FMDP, N-acyl peptide, kanosamine-6-P; functional homolog of S. cerevisiae Gfa1p; growth-phase regulated; catalytic Cys [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 497338 498959 + orf19.1617 497338 498959 1 497338 498959 497491 498663 orf19.9184|IPF12263.2|IPF17776.2|Contig4-2597_0008|orf6.1029|orf6.6455|YDR282C|CA6191|CaO19.1617|IPF17776 Protein similar to S. cerevisiae Ydr282cp; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 498964 502918 + orf19.1616 498964 502918 1 498964 502918 499574 502918 FGR23 orf19.9183|PGA40|IPF12262.3|IPF12624.3|Contig4-2400_0003|orf6.1089|orf6.555|CA0267|orf6.1030|CaO19.1616|IPF12262|IPF12262.2 Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth; transcriptionally repressed by A1p and Alpha2p in white-phase cells, a-specific and induced by alpha factor [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr3 503135 503265 - ntar_565 503135 503265 1 503265 503135 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 504601 506480 + orf19.1614 504601 506480 1 504601 506480 504793 506400 MEP1 orf19.9181|MEP3|IPF12620.1|IPF18990.2|Contig4-2400_0002|orf6.1090|orf6.1335|CA0302|CaO19.1614 Ammonium permease; Mep1p is a more efficient ammonium permease than Mep2p, whereas Mep2p has additional regulatory role; not essential for viability; 11 predicted transmembrane regions; low mRNA abundance; hyphal downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 507107 509506 + orf19.1613 507107 509506 1 507107 509506 507204 509255 ILV2 orf19.9180|IPF12617.3|IPF14829.2|orf6.1091|orf6.1336|CA0428|CaO19.1613 Protein described as acetolactate synthase; regulated by Gcn4p; induced in response to amino acid starvation (3-aminotriazole treatment); protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 509506 510777 - orf19.1611 509506 510777 1 510777 509506 510706 509774 orf19.9179|IPF18870.2|IPF14827.2|orf6.1338|orf6.1937|CA0429|CaO19.1611|IPF14827 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 509610 509818 + ntar_566 509610 509818 1 509610 509818 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 510096 510464 + ntar_567 510096 510464 1 510096 510464 510096 510464 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 511380 512739 + orf19.1610 511380 512739 1 511380 512739 511401 512549 orf19.9178|IPF13567.2|IPF14825.1|orf6.1339|orf6.1936|CA0799|CaO19.1610|IPF14825 Putative protein of unknown function, transcription is activated in the presence of elevated CO2; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr3 512816 514970 + orf19.1609 512816 514970 1 512816 514970 512849 514849 orf19.9177|IPF13565.2|IPF19865.2|Contig4-1822_0002|Contig4-1822_0003|orf6.1340|orf6.1935|CA0798|KRI1|CaO19.1609|IPF13565 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 514895 516765 - orf19.1608 514895 516765 1 516765 514895 516765 514999 orf19.9176|IPF25615.1|IPF13564.2|Contig4-1822_0006|orf6.1934|CA0797|CaO19.1608|AYS1|CaO19.9176|IPF13564 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr3 517527 521066 - orf19.1607 517527 521066 1 521066 517527 520518 517729 ALR1 orf19.9175|IPF13562.2|IPF14418.3|Contig4-2034_0002|Contig4-2034_0003|Contig4-2034_0004|Contig4-2260_0010|orf6.1088|orf6.1933|CA0796|CaO19.1607 Putative transporter of divalent cations; hyphal-induced expression; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 521229 521679 + ntar_568 521229 521679 1 521229 521679 521458 521679 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 524072 526065 + orf19.1606 524072 526065 1 524072 526065 524221 525846 orf19.9174|IPF19678.2|IPF19688.1|Contig4-2260_0002|orf6.1087|CA0301|CaO19.1606|IPF19688 Predicted ORF in Assemblies 19, 20 and 21; Plc1p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 525976 526855 - orf19.227 525976 526855 1 526855 525976 526855 526526 COX7 orf19.7857|IPF27081.1|IPF15250.2|Contig4-2074_0001|orf6.215|CA0031|CaO19.227|CaO19.7857 Predicted ORF in Assemblies 19, 20 and 21; flucytosine induced; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr3 527079 528909 - orf19.229 527079 528909 2 528909|528437 528719|527079 528760 527187 orf19.7859|IPF27020.1|IPF15248.2|Contig4-2074_0003|orf6.217|CA0032|CaO19.229|CaO19.7859|IPF15248 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr3 527409 527945 + ntar_569 527409 527945 1 527409 527945 527613 527945 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 527613 528090 + ntar_570 527613 528090 1 527613 528090 527613 527945 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 528670 528820 + ntar_571 528670 528820 1 528670 528820 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 529176 531895 - orf19.230 529176 531895 1 531895 529176 531895 529253 orf19.7860|IPF26959.1|IPF15244.3|Contig4-2074_0005|Contig4-2074_0006|orf6.1121|orf6.1122|orf6.218|CA0320|CaO19.230|IPF15244.5f|CA0319|IPF15244.3f|IPF19858.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr3 532592 535177 + orf19.231 532592 535177 1 532592 535177 532714 535038 APL2 orf19.7861|IPF15242.2|IPF29874.1|Contig4-2074_0008|orf6.1123|orf6.518|CA0321|CaO19.231 Phosphorylated protein of unknown function; mutation confers hypersensitivity to toxic ergosterol analog; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 534980 536208 - orf19.232 534980 536208 1 536208 534980 536063 535149 orf19.7862|IPF19038.2|IPF10105.2|Contig4-2868_0002|Contig4-2868_0003|orf6.1124|orf6.519|CA0101|CaO19.232|MED7|IPF10105 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr3 536292 537194 + orf19.233.1 536292 537194 2 536292|536626 536551|537194 536518 536963 HRT1 IPF19089.2|IPF10102.1|Contig4-2868_0004|Contig4-2868_0005|CA6169|IPF10102 Protein similar to S. cerevisiae Hrt1p, which is a component of a nuclear ubiquitin-protein ligase complex involved in cell cycle control; induced under hydroxyurea treatment [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 537086 538355 - orf19.234 537086 538355 2 538355|538101 538180|537086 538230 537223 PHA2 orf19.7864|IPF10101.2|IPF19241.1|PHA2.3|Contig4-2868_0006|orf6.953|orf6.521|CA0238 Predicted ORF in Assemblies 19, 20 and 21; decreased expression observed in an ssr1 homozygous null mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 538530 539545 - orf19.236 538530 539545 1 539545 538530 539506 538931 RPL9B orf19.7866|IPF27046.1|IPF10099.1|Contig4-2868_0008|orf6.955|CA0239|RPL9|CaO19.236|CaO19.7866 Predicted ribosomal protein; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 539874 541299 - orf19.238 539874 541299 1 541299 539874 541085 539985 CCP1 orf19.7868|orf6.957|orf6.2684|IPF10098.1|IPF18721.2|Contig4-2868_0011|CA6170|CaO19.238 Similar to cytochrome-c peroxidase N terminus; transcription is negatively regulated by Rim101p or alkaline pH; transcription induced by interaction with macrophage or low iron; oxygen-induced activity [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 541971 546608 - orf19.239 541971 546608 1 546608 541971 546181 542270 orf19.7869|IPF27079.1|IPF10096.2|Contig4-2868_0013|orf6.2685|CA1264|STH1|CaO19.7869|CaO19.239 Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 547167 548207 + orf19.240 547167 548207 1 547167 548207 547229 547879 orf19.7870|IPF27040.1|IPF10510.2|Contig4-2868_0015|orf6.2686|CA1265|FMP16|CaO19.7870|CaO19.240|IPF10510 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr3 548180 549629 - orf19.242 548180 549629 1 549629 548180 549453 548236 SAP8 orf19.7872|IPF27022.1|IPF10508.1|Contig4-2868_0016|orf6.2688|CA1266|CaO19.7872|CaO19.242 Secreted aspartyl proteinase; regulated by growth phase, temperature, and white-opaque switch; highly expressed in opaque cells; expressed upon deep epidermal invasion; greater expression during vaginal infection than oral infection [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr3 551093 551164 + tm(cau)1 551093 551164 1 551093 551164 tM(CAU)1.2 tRNA-Met predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 551191 552198 + orf19.242.2 551191 552198 1 551191 552198 551644 551832 IPF10503.2|CA1267|YSY6 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 551879 553489 - orf19.243 551879 553489 1 553489 551879 553435 552398 OXR1 orf19.7873|IPF10502.1|IPF18720.2|Contig4-2680_0004|orf6.1270|orf6.2689|CA6171|CaO19.243 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 553641 554480 - orf19.244 553641 554480 1 554480 553641 554476 553778 DCG1 orf19.7874|IPF27037.1|IPF10499.2|Contig4-2680_0006|orf6.1271|CA0390|CaO19.244|CaO19.7874 Transcription is regulated by Nrg1p and Mig1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 554655 556529 + orf19.245 554655 556529 1 554655 556529 554671 556137 DDC1 orf19.7875|IPF10496.2|IPF17370.2|Contig4-2680_0007|Contig4-2680_0008|orf6.1272|orf6.602|CA0391|CaO19.245 Transcription is induced during filamentous growth; regulated by Nrg1p, Tup1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 556671 558902 + orf19.246 556671 558902 1 556671 558902 556671 558902 orf19.7877|IPF17369.3|IPF10495.2|Contig4-2680_0011|orf6.1273|orf6.1996|orf6.601|CA0129|CaO19.246|IPF10495 Predicted ORF in Assemblies 19, 20 and 21; fungal-specific (no human or murine homolog) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 558224 559741 - orf19.247 558224 559741 1 559741 558224 559630 558899 orf19.7878|IPF14701.2|IPF10493.3|Contig4-2680_0012|orf6.1995|orf6.600|CA0831|CaO19.247|IPF10493|IPF10493.5eoc Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 559738 563407 + orf19.248 559738 563407 1 559738 563407 559914 563213 APL5 orf19.7879|IPF14699.2|IPF29913.1|Contig4-1809_0004|orf6.1994|CA0830|CaO19.248|CaO19.7879 Phosphorylated protein, not essential for viability; similar to S. cerevisiae Apl5p, which is a subunit of the AP-3 adaptor complex involved in Golgi-to-vacuole transport [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 563233 564569 - orf19.250 563233 564569 1 564569 563233 564304 563423 SLC1 orf19.7881|IPF27028.1|IPF19886.1|Contig4-1809_0003|orf6.1992|CA0829|CaO19.250|CaO19.7881 Protein repressed during the mating process [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 565143 566008 - orf19.251 565143 566008 1 566008 565143 565950 565240 orf19.7882|orf6.1991|IPF17186|IPF17186.2|IPF29885.1|Contig4-1809_0005|YDR533C|CA0828|CaO19.251 ThiJ/PfpI protein family; antigenic (Cand a 3 allergen); binds human immunoglobulin E; 2 N-glycosylation motifs; alkaline, fluconazole, Hog1p-downregulated; induced in core stress response or by oxidative stress (via Cap1p) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 566949 567245 + ntar_572 566949 567245 1 566949 567245 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 567131 568221 - orf19.252 567131 568221 1 568221 567131 568051 567698 orf19.7884|orf19.7885|IPF18859.2|IPF29889.1|orf6.1989|orf6.1988|orf19.253|CaO19.252|CaO19.7884 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 568641 570052 - orf19.254 568641 570052 1 570052 568641 570050 568722 orf19.7886|IPF18861.2|IPF16370.2|Contig4-2723_0001|orf6.1987|orf6.691|CA0152|CaO19.254|IPF16368.3f Predicted ORF in Assemblies 19, 20 and 21; Hog1p-downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr3 570073 573752 - orf19.255 570073 573752 2 573752|572848 573546|570073 572779 570263 ZCF1|orf19.7887|IPF26971.1|IPF16368.2|Contig4-2723_0002|Contig4-2723_0003|Contig4-2723_0004|orf6.692|CA0153|IPF16368.5f Predicted zinc-cluster protein of unknown function; possibly transcriptionally regulated upon hyphal formation; intron in 5'-UTR [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=F] Ca21chr3 572938 573620 + orf19.257 572938 573620 1 572938 573620 572938 573264 orf19.7889|orf6.694|orf6.1190|IPF27080.1|IPF29899.1|CaO19.257 [NOT TRANSCRIBED?] Transcription is negatively regulated by Sfu1p; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr3 576627 577385 + orf19.258 576627 577385 1 576627 577385 576627 577385 orf19.7890|IPF15540.1|IPF13725.1|Contig4-2723_0007|orf6.1191|orf6.1453|CA0486|CaO19.258|IPF15540 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 577684 578645 + orf19.259 577684 578645 1 577684 578645 577762 578517 orf19.7891|IPF19234.2|IPF13724.1|Contig4-2723_0008|orf6.1454|CA0487|CaO19.7891|CaO19.259|IPF13724 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 578538 580612 - orf19.260 578538 580612 1 580612 578538 580399 578645 SLD1 orf19.7892|IPF13723.2|IPF29880.1|Contig4-2723_0009|orf6.1455|orf6.548|CA0109|CaO19.260|IPF13723 Sphingolipid delta-8 desaturase, catalyzes desaturation at carbon-8 in the long-chain base moiety of ceramides during glucosylceramide synthesis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 580748 582721 - orf19.261 580748 582721 1 582721 580748 582644 580884 orf19.7894|IPF12686.3|IPF13722.2|Contig4-2723_0010|orf6.1456|orf6.2014|orf6.549|CA0488|CaO19.261|SEC59 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 583155 586967 + orf19.262 583155 586967 1 583155 586967 583232 586945 SMC3 orf19.7895|IPF12682.2|IPF18780.2|IPF18779.1|Contig4-2723_0011|orf6.2013|orf6.2357|orf6.2358|CA0846|CA6315|orf19.263|SMC3.5f Protein likely to be essential for growth, based on an insertional mutagenesis strategy; similar to S. cerevisiae Smc3p, which is an ATPase involved in sister chromatid cohesion [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 586983 587157 - ntar_573 586983 587157 1 587157 586983 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 588367 589623 + orf19.263.1 588367 589623 2 588367|589095 588476|589623 588474 589304 Predicted ORF in Assembly 20 and 21; gene has intron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 590127 591889 + orf19.264 590127 591889 1 590127 591889 590523 591875 orf19.7896|IPF16314.2|IPF29883.1|Contig4-2401_0007|Contig4-2401_0009|orf6.2012|orf6.2359|CA0845|CaO19.264|IPF16314 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr3 591862 592106 - tf(gaa)1 591862 592106 2 592106|592054 592070|591862 tF(GAA)1.2 tRNA-Phe predicted by tRNAscan-SE; has atypical tertiary T15A48 basepair (rather than R15Y48 basepair) [label_first_exon=CGD label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 592115 592187 - tr(ucu)1 592115 592187 1 592187 592115 tR(UCU)1.2 tRNA-Arg predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 593881 595383 + orf19.265 593881 595383 1 593881 595383 593881 595383 orf19.7897|IPF27009.1|IPF16342.2|Contig4-2401_0010|orf6.2360|CA6172|CaO19.265|CaO19.7897|IPF27009 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 595365 599493 - orf19.267 595365 599493 1 599493 595365 599391 595750 orf19.7899|IPF19341.2|IPF11460.2|orf6.2362|CA1060|CaO19.267|IPF11460 Protein required for normal filamentous growth; mRNA binds to She3p; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 599659 601078 - orf19.268 599659 601078 1 601078 599659 601053 599710 orf19.7900|IPF11452.2|IPF9532.3|Contig4-2183_0007|Contig4-2524_0002|orf6.2363|orf6.3181|CA1599|CaO19.268|RAD28|IPF11452 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 600501 600644 + ntar_574 600501 600644 1 600501 600644 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 601274 602794 + orf19.269 601274 602794 1 601274 602794 601357 602733 SES1 orf19.7901|IPF9534.2|IPF18778.2|Contig4-2183_0004|orf6.3180|CA1598|CaO19.269 Seryl-tRNA synthetase; charges the tRNA that recognizes the CUG codon, which typically specifies Leu, but specifies Ser in C. albicans; complements S. cerevisiae ses1 mutant viability; soluble protein in hyphae; macrophage-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 602990 603625 + orf19.270 602990 603625 1 602990 603625 603155 603469 orf19.7902|IPF27092.1|IPF9536.2|Contig4-2183_0003|orf6.3179|CaO19.270|CaO19.7902 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 604209 604985 + orf19.271 604209 604985 1 604209 604985 604209 604985 ADH4 orf19.7903|IPF9538|Contig4-2183_0001|IPF27033.1|IPF9538.2|Contig4-2499_0006|orf6.3178|CA1597|CaO19.271|CaO19.7903 [NOT TRANSCRIBED?] Protein not essential for viability; transcription is increased in an azole-resistant strain overexpressing MDR1; transcription is increased in populations of cells exposed to fluconazole over multiple generations [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 605087 607512 - orf19.272 605087 607512 1 607512 605087 607347 605191 FAA21 orf19.7904|IPF26977.1|IPF9539.2|Contig4-2499_0005|orf6.3177|CA1596|FAA2-2|CaO19.272|CaO19.7904 Predicted acyl CoA synthetase; upregulated upon phagocytosis; transcription is regulated by Nrg1p and Mig1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 609807 611400 - orf19.273 609807 611400 1 611400 609807 611088 610081 orf19.7905|IPF9544.2|IPF29884.1|Contig4-2499_0001|orf6.3176|CA1595|CaO19.273|IPF9544 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 612058 615371 + orf19.274 612058 615371 1 612058 615371 612138 615311 TFC4 orf19.7906|IPF27095.1|IPF10122.3|Contig4-2667_0008|Contig4-2667_0010|orf6.3175|orf6.4803|CA2774|CaO19.274|IPF10122.2 Predicted ORF in Assemblies 19, 20 and 21; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 615488 616790 + orf19.275 615488 616790 1 615488 616790 615566 616138 orf19.7907|IPF27052.1|IPF10123.1|Contig4-2667_0007|orf6.4804|CA2775|CaO19.7907|POP5|CaO19.275 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 615911 617647 - orf19.276 615911 617647 1 617647 615911 617520 616108 orf19.7908|IPF27015.1|IPF10124.1|Contig4-2667_0006|orf6.4805|CA2776|CaO19.276|CaO19.7908|IPF10124 Predicted ORF in Assemblies 19, 20 and 21; increased transcription is observed in an azole-resistant strain that overexpresses MDR1 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 617185 617490 + ntar_575 617185 617490 1 617185 617490 617185 617367 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 618098 619948 + orf19.277 618098 619948 1 618098 619948 618203 619747 THI6 orf19.7909|IPF27007.1|IPF10126.2|Contig4-2667_0004|orf6.4806|CA2777|CaO19.7909|CaO19.277 Putative thiamin-phosphate pyrophosphorylase, hydroxyethylthiazole kinase; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 619764 621279 - orf19.278 619764 621279 1 621279 619764 621211 619784 orf19.7910|IPF27013.1|IPF10127.2|Contig4-2667_0002|orf6.4807|CA2778|CaO19.278|MTR1|CaO19.7910|MTR Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 621869 622279 + orf19.279 621869 622279 1 621869 622279 621869 622279 orf19.7911|IPF27060.1|IPF19768.1|orf6.4808|CA2779|CaO19.279|CaO19.7911|IPF3836 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 622380 622790 - orf19.280 622380 622790 1 622790 622380 622790 622380 orf19.7912|IPF19669.1|Contig4-3050_0012|orf6.4297|orf6.4809|CaO19.7912|CaO19.280 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 623049 624146 + orf19.281 623049 624146 1 623049 624146 623049 624146 orf19.7913|IPF27023.1|IPF3798.2|orf6.4810|CA2780|CaO19.7913|CaO19.281|IPF3831 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 624288 624944 + orf19.284 624288 624944 1 624288 624944 624288 624944 orf19.7916|IPF27036.1|IPF3805.2|orf6.4813|CA2781|CaO19.284|CaO19.7916|IPF3821 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 625144 625990 + orf19.285 625144 625990 1 625144 625990 625194 625583 orf19.7917|IPF27074.1|IPF3806.1|Contig4-3050_0029|orf6.4814|CA2782|CaO19.285|CaO19.7917|IPF3806 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 626061 626594 + orf19.286 626061 626594 1 626061 626594 626061 626594 orf19.7918|IPF27054.1|IPF3808.1|IPF3808|Contig4-3050_0026|orf6.4815|CA2783|ATG10|CaO19.7918|CaO19.286 Decreased transcription is observed upon fluphenazine treatment; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 626403 627280 - orf19.287 626403 627280 1 627280 626403 627209 626625 orf19.7919|IPF27050.1|IPF3810.1|Contig4-3050_0025|orf6.4816|CA2784|CaO19.7919|CaO19.287|IPF3810 Predicted ORF in Assemblies 19, 20 and 21; repressed by nitric oxide; identified in detergent-resistant membrane fraction (possible lipid raft component) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 627761 630135 - orf19.288 627761 630135 1 630135 627761 630029 628185 orf19.7920|IPF26987.1|IPF3814.2|Contig4-3050_0022|orf6.4817|CA2785|MET13|CaO19.7920|CaO19.288 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 630303 634859 - orf19.290 630303 634859 1 634859 630303 634859 630516 KRE5 orf19.7922|IPF27067.1|IPF3818.3|Contig4-3050_0020|orf6.4303|orf6.4819|CA2786|GPT1|CaO19.290|KRE5.3eoc|IPF3818.2 Predicted UDP-glucose:glycoprotein glucosyltransferase; required for wild-type 1,6-beta-D-glucan biosynthesis, hyphal growth, and virulence in mouse IV infection; production in S. cerevisiae partially complements defects of a kre5 mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 635019 635983 - orf19.291 635019 635983 1 635983 635019 635964 635044 orf19.7923|IPF27029.1|IPF19948.1|Contig4-3050_0016|Contig4-3050_0017|orf6.4302|CA2409|CaO19.291|CaO19.7923|IPF19948 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 636037 636896 - orf19.292 636037 636896 1 636896 636037 636896 636240 orf19.7924|IPF27038.1|IPF3821.1|orf6.4301|CaO19.7924|CaO19.292 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr3 637038 638135 - orf19.295 637038 638135 1 638135 637038 638135 637038 orf19.7927|IPF27021.1|IPF3831.1|Contig4-3050_0013|orf6.4298|CaO19.295|CaO19.7927 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 638392 638802 + orf19.296 638392 638802 1 638392 638802 638392 638802 orf19.7928|IPF27058.1|IPF3833.1|orf6.4297|CA2408|CaO19.296|CaO19.7928|IPF3833 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 638903 639539 - orf19.297 638903 639539 2 639539|639329 639411|638903 639475 638903 DTD2 orf19.7929|IPF27061.1|IPF3836.2|Contig4-3050_0011|orf6.4296|CaO19.7929|CaO19.297 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 639474 639977 + orf19.298 639474 639977 1 639474 639977 639474 639977 IPF27056.1|IPF18470.1|orf6.4295|CaO19.298|CaO19.7930 [NOT TRANSCRIBED?] ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 639684 641310 - orf19.299 639684 641310 1 641310 639684 641124 639712 ECM14 orf19.7931|IPF27014.1|IPF3838.2|Contig4-3050_0009|orf6.4294|CA2407|CaO19.299|CaO19.7931 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 641748 643681 + orf19.300 641748 643681 1 641748 643681 641881 643464 AIP2 orf19.7932|orf19.7933|IPF26999.1|IPF3840.1|Contig4-3050_0007|orf6.4293|CA2406|CaO19.300|DLD2|CaO19.7932 Protein described as an actin interacting protein; regulated by Gcn4p; induced in response to amino acid starvation (3-aminotriazole treatment); repressed in the presence of elevated CO2 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 643766 646852 - orf19.301 643766 646852 1 646852 643766 646395 644134 PGA18 orf19.7933|IPF26975.1|IPF3844.2|Contig4-3050_0006|orf6.4292|CA2405|CaO19.301|CaO19.7933|IPF3844 Putative GPI-anchored protein of unknown function; regulated by Nrg1p, Tup1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr3 651518 652612 + orf19.302 651518 652612 1 651518 652612 651675 652157 orf19.7934|IPF27043.1|IPF1468.1|Contig4-2823_0003|orf6.4440|CA2508|BET5|CaO19.302|CaO19.7934 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 652786 654420 + orf19.304 652786 654420 1 652786 654420 652875 654392 orf19.7936|IPF26998.1|IPF1471.2|Contig4-2823_0004|orf6.4442|CA2509|CaO19.7936|CaO19.304|IPF1471 Putative transporter similar to MDR proteins; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 654045 654379 - ntar_576 654045 654379 1 654379 654045 654379 654221 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 654462 655960 + orf19.305 654462 655960 1 654462 655960 654607 655857 orf19.7937|IPF27019.1|IPF1472.2|Contig4-2823_0007|orf6.4443|CA2510|CaO19.7937|CaO19.305|IPF1472 Predicted ORF in Assemblies 19, 20 and 21; greater mRNA abundance observed in a cyr1 homozygous null mutant than in wild type [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 656146 658073 + orf19.306 656146 658073 1 656146 658073 656186 658045 USO5 orf19.7938|IPF26986.1|IPF1474.2|Contig4-2823_0010|orf6.4444|CA2511|ABPD|CaO19.306|CaO19.7938|IPF1474 Protein of unknown function; transcription is induced upon filamentous growth and in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 657992 659958 - orf19.307 657992 659958 1 659958 657992 659570 658098 orf19.7939|IPF27011.1|IPF1476.1|Contig4-2823_0011|orf6.4445|CA2512|HFI1|CaO19.307|CaO19.7939 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 660884 662617 + orf19.308 660884 662617 1 660884 662617 660968 662503 orf19.7940|IPF27003.1|IPF1478.1|orf6.4446|CA2513|SNG1|CaO19.7940|CaO19.308 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 663303 664880 - orf19.309 663303 664880 1 664880 663303 664880 663303 DAL5 orf19.7941|IPF27000.1|IPF1479.1|Contig4-1938_0003|orf6.4447|CA6173|CaO19.309|DAL51|CaO19.7941|IPF1479 Putative allantoate permease; nitrogen catabolite repressed gene, induced in absence of preferred N sources; gene regulation by nitrogen source requires Gat1p; fungal-specific (no human or murine homolog) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr3 665755 667275 - orf19.310 665755 667275 1 667275 665755 667275 665755 orf19.7943|IPF1480.1|IPF1481.1|Contig4-1938_0004|Contig4-1938_0005|orf6.4448|orf6.4450|CA6248|orf19.312|CA6247|ECM181.5f|ECM181.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 667605 669317 - orf19.313 667605 669317 1 669317 667605 669317 667605 DAL4 orf19.7944|IPF27017.1|IPF1484.2|Contig4-2361_0006|orf6.4451|orf6.5645|CA2514|FUR41|CaO19.313|FUR4 Putative allantoin permease; fungal-specific (no human or murine homolog) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 669559 669745 + ntar_577 669559 669745 1 669559 669745 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 670708 674032 + orf19.314 670708 674032 1 670708 674032 670807 673806 orf19.7946|IPF6747.2|IPF29919.1|Contig4-2797_0025|orf6.5644|CA3394|CaO19.7946|STB2|CaO19.314|IPF6747 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 673373 674486 - orf19.315 673373 674486 1 674486 673373 674413 673799 orf19.7947|IPF27041.1|IPF6748.2|Contig4-2797_0022|orf6.5643|CA3393|CaO19.315|CaO19.7947|IPF6748 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 674575 675723 + orf19.316 674575 675723 1 674575 675723 674678 675574 SEC13 orf19.7948|IPF27025.1|IPF6749.2|Contig4-2797_0021|orf6.5642|CA3392|CaO19.316|CaO19.7948 Protein described as protein transport factor; antigenic during murine systemic infection; macrophage-downregulated protein abundance; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 675645 676658 - orf19.317 675645 676658 1 676658 675645 676625 675702 orf19.7949|IPF6750.1|IPF19266.2|Contig4-2797_0017|orf6.462|orf6.5641|CA3391|CaO19.317|PNP1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 676900 678515 - orf19.318 676900 678515 1 678515 676900 678440 677031 orf19.7950|IPF6752.1|IPF19265.1|Contig4-2797_0013|orf6.463|orf6.5640|CAF17|CaO19.318|CA3390 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 678696 679377 - orf19.319 678696 679377 1 679377 678696 679196 678846 orf19.7951|IPF6754.1|IPF19264.2|Contig4-2797_0011|orf6.464|orf6.5639|CA3389|CaO19.319|IPF6754 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr3 680021 681186 + orf19.320 680021 681186 1 680021 681186 680123 681124 orf19.7952|IPF27026.1|IPF6755.1|Contig4-2797_0005|orf6.5638|CA3388|RSD1|CaO19.320|CaO19.7952|IPF6755 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 680638 680969 - ntar_578 680638 680969 1 680969 680638 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 681270 681359 - tk(cuu)1 681270 681359 2 681359|681305 681323|681270 tK(CUU)1.2 tRNA-Lys predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 681475 683441 - orf19.321 681475 683441 1 683441 681475 683327 681501 orf19.7953|IPF6757.1|IPF29879.1|Contig4-2797_0003|Contig4-2797_0004|orf6.5637|CA3387|MUP3|CaO19.7953|CaO19.321 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr3 683808 684149 + ntar_579 683808 684149 1 683808 684149 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 684525 684741 + ntar_580 684525 684741 1 684525 684741 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 684595 685029 - orf19.322 684595 685029 1 685029 684595 685029 684595 orf19.7954|IPF6758.2|IPF29887.1|orf6.5636|CA3386|CaO19.322|IPF6758 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 685028 689768 + orf19.323 685028 689768 1 685028 689768 685198 689637 orf19.7955|IPF6764.2|IPF29893.1|Contig4-2777_0010|orf6.5635|CA3385|CaO19.7955|CaO19.323|DRS23 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 690000 693000 + orf19.325 690000 693000 1 690000 693000 690043 692838 orf19.7957|IPF26957.1|IPF8362.2|orf6.5633|CA3384|CaO19.7957|CFT2|CaO19.325|IPF8362 Putative protein of unknown function; heterozygous null mutant exhibits hypersensitivity to parnafungin and cordycepin in the C. albicans fitness test; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 692255 692399 - ntar_581 692255 692399 1 692399 692255 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 693005 693708 + orf19.326 693005 693708 1 693005 693708 693145 693600 orf19.7958|IPF27062.1|IPF8359.2|Contig4-2705_0001|orf6.5632|CA3383|CaO19.7958|CaO19.326|IPF8359 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 693564 694340 - orf19.327 693564 694340 1 694340 693564 694289 693888 HTA3 orf19.7959|IPF27053.1|IPF8358.1|Contig4-2705_0004|orf6.5631|CA3382|CaO19.7959|HTZ1|CaO19.327 Protein described as histone H2A; amphotericin B repressed; flucytosine induced; RNA abundance regulated by tyrosol and cell density [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 694490 696551 - orf19.328 694490 696551 1 696551 694490 696524 694542 NPR2 orf19.7960|IPF26980.1|IPF8357.2|Contig4-2705_0009|orf6.5630|CA3381|CaO19.7960|CaO19.328 Predicted ORF in Assemblies 19, 20 and 21; induced during infection of murine kidney, compared to growth in vitro; has murine homolog [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 696706 698394 - orf19.329 696706 698394 1 698394 696706 698366 696999 orf19.7961|IPF27016.1|IPF8351.2|Contig4-2705_0010|Contig4-2705_0011|orf6.5629|CA3380|CaO19.329|MSL5|CaO19.7961 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 698506 699250 - orf19.331 698506 699250 1 699250 698506 699226 698552 orf19.7963|IPF27042.1|IPF8350.1|Contig4-2705_0012|orf6.5627|CA3379|CaO19.331|CaO19.7963|IPF8350 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr3 698632 699116 + ntar_582 698632 699116 1 698632 699116 698751 699116 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 699225 699995 + orf19.330.1 699225 699995 1 699225 699995 699419 699652 IPF26964.1|IPF8348.1|CA3378|RUB1 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 699566 701925 - orf19.332 699566 701925 1 701925 699566 701824 699719 orf19.7964|IPF8347.2|IPF19023.2|Contig4-2705_0015|orf6.1189|orf6.5626|CA3377|CLF1|CaO19.332 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 702109 703112 - orf19.332.1 702109 703112 1 703112 702109 702579 702295 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 703184 703838 + te(uuc)1 703184 703838 2 703184|703243 703220|703838 tE(UUC)1.2 tRNA-Glu predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 704137 706295 + orf19.333 704137 706295 1 704137 706295 704239 705819 FCY2 orf19.7965|FCY22|IPF8342.3|IPF12764.2|Contig4-2216_0002|Contig4-2705_0018|orf6.1188|orf6.1275|orf6.5625|CA0357|FCY21|CaO19.333 Putative purine-cytosine permease of pyrimidine salvage; similar to S. cerevisiae Fcy2p; mutation associated with resistance to flucytosine in clinical isolates; transposon mutation affects filamentation; farnesol-upregulated in biofilm [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 708195 709396 - orf19.334 708195 709396 1 709396 708195 709157 708585 orf19.7966|IPF12758.2|IPF29886.1|Contig4-2216_0007|orf6.1276|orf6.7218|CA0394|CaO19.334|IPF12758.5f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 711213 711356 + ntar_583 711213 711356 1 711213 711356 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 714072 716861 + orf19.335 714072 716861 1 714072 716861 714305 716746 orf19.7967|IPF26972.1|IPF13709.2|orf6.7219|CA4629|CaO19.7967|CaO19.335|SDS22|IPF13709 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr3 716491 717501 - orf19.336 716491 717501 1 717501 716491 717415 716906 YAH1 orf19.7969|orf6.7220|IPF27048.1|IPF1537.1|Contig4-3090_0001|CA4630|CaO19.7969|CaO19.336|IPF1537 Similar to oxidoreductases; transcriptionally regulated by iron; expression greater in high iron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 717656 718605 - orf19.337 717656 718605 2 718605|718346 718470|717656 718563 717787 orf19.7970|IPF27044.1|IPF1535.1|Contig4-3090_0002|orf6.7221|CA4631|VTI1|CaO19.337 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 718764 722112 - orf19.338 718764 722112 1 722112 718764 722020 718877 orf19.7971|IPF27096.1|IPF1531.2|Contig4-3090_0006|Contig4-3090_0007|orf6.7222|CA4632|CaO19.7971|CaO19.338|IPF1531 Predicted ORF in Assemblies 19, 20 and 21; Hog1p-downregulated; shows colony morphology-related gene regulation by Ssn6p; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 722844 724725 - orf19.339 722844 724725 1 724725 722844 724678 722954 NDE1 orf19.7972|IPF26993.1|IPF1529.1|NDH1|Contig4-3090_0011|orf6.7223|CA4633|CaO19.7972|CaO19.339 Putative NADH dehydrogenase that could act alternatively to complex I in respiration; caspofungin repressed; fungal-specific (no human or murine homolog); transcription is upregulated in both intermediate and mature biofilms [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 725078 726306 - orf19.340 725078 726306 1 726306 725078 726276 725677 orf19.7973|IPF27045.1|IPF1526.1|Contig4-3090_0013|orf6.7224|CA4634|CaO19.340|SRN2|CaO19.7973|IPF1526 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 725320 725812 + ntar_584 725320 725812 1 725320 725812 725630 725812 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 726435 728484 - orf19.341 726435 728484 1 728484 726435 728410 726479 orf19.7974|IPF26983.1|IPF1524.2|Contig4-3090_0015|orf6.7225|TPO3|CA4635|CaO19.7974|CaO19.341|IPF1524 Putative spermidine export pump; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 726628 727298 + ntar_585 726628 727298 1 726628 727298 726819 726989 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 727426 727783 + ntar_586 727426 727783 1 727426 727783 727431 727691 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 728994 731040 - orf19.342 728994 731040 1 731040 728994 730949 728994 BMT7 orf19.7975|IPF26981.1|IPF1520.1|Contig4-3090_0018|orf6.7226|CA4636|CaO19.7975|WRY8|CaO19.342|IPF1520 Putative beta-mannosyltransferase, member of a 9-gene family that includes characterized genes BMT1, BMT2, BMT3, and BMT4 with roles in beta-1,2-mannosylation of cell wall phosphopeptidomannan; downregulated in an azole-resistant strain [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chr3 729081 729470 + ntar_587 729081 729470 1 729081 729470 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 732851 734535 - orf19.344 732851 734535 1 734535 732851 734432 733617 orf19.7977|IPF27032.1|IPF1514.2|Contig4-3090_0023|orf6.7228|CA4637|CaO19.7977|CaO19.344|IPF1514 Predicted ORF in Assemblies 19, 20 and 21; increased transcription is observed upon fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2; possibly transcriptionally regulated by Tac1p; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 737469 739081 + orf19.345 737469 739081 1 737469 739081 737586 739061 orf19.7978|IPF27012.1|IPF1510.1|Contig4-3090_0030|orf6.7229|CA4638|UGA21|CaO19.7978|CaO19.345|UGA2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 738748 738930 - ntar_588 738748 738930 1 738930 738748 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 739053 741071 - orf19.346 739053 741071 1 741071 739053 740761 739199 orf19.7979|IPF27006.1|IPF1509.2|Contig4-3090_0031|orf6.7230|CA4639|CaO19.346|CaO19.7979|IPF1509 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to 5-fluorocytosine (5-FC) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 743253 744093 - ntar_589 743253 744093 1 744093 743253 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 743351 744193 + orf19.347 743351 744193 1 743351 744193 743351 744193 RSN1 orf19.7980|IPF27030.1|IPF1506.1|Contig4-3090_0035|orf6.7231|CA4640|CaO19.7980|CaO19.347|IPF1506 Protein induced during the mating process [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr3 745746 748202 + orf19.348 745746 748202 1 745746 748202 745944 748100 SKN2 orf19.7981|IPF26976.1|IPF1505.2|Contig4-3090_0037|orf6.7232|CA4641|CaO19.348|CaO19.7981|IPF1505 Protein with a potential role in beta-1,6 glucan biosynthesis; has similarity to Kre6p and Skn1p; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 746170 748211 - ntar_590 746170 748211 1 748211 746170 747451 747164 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 748333 750702 - orf19.349 748333 750702 1 750702 748333 750600 748495 orf19.7982|IPF26978.1|IPF1500.2|Contig4-3090_0039|orf6.7233|CA4642|CaO19.7982|NCA2|CaO19.349|IPF1500 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 748387 748645 + ntar_591 748387 748645 1 748387 748645 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 750849 751876 - orf19.350 750849 751876 1 751876 750849 751678 750923 PRE9 orf19.7983|IPF27035.1|IPF1499.1|Contig4-3090_0040|orf6.7234|Y13|CA4643|CaO19.7983|CaO19.350 Alpha3 (C9) subunit of the 20S proteasome; transcription is regulated by Mig1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 752032 752765 + orf19.351 752032 752765 1 752032 752765 752128 752595 orf19.7984|IPF27055.1|IPF1497.1|Contig4-3090_0042|orf6.7235|CA4644|CaO19.7984|CaO19.351|IPF1497 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 752309 752858 - ntar_592 752309 752858 1 752858 752309 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 752835 754611 + orf19.352 752835 754611 1 752835 754611 752841 754472 orf19.7985|IPF26995.1|IPF1496.1|Contig4-3090_0045|orf6.7236|CA4645|CaO19.352|CaO19.7985|IPF1496 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 754421 755713 - orf19.353 754421 755713 1 755713 754421 755571 754516 ULP1 orf19.7986|IPF27024.1|IPF1495.1|Contig4-3090_0046|orf6.7237|CA4646|CaO19.353|ULP3|CaO19.7986|IPF1495 Putative SUMO deconjugation enzyme that cleaves the small ubiquitin-like modifier (SUMO) off proteins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 755812 757523 + orf19.354 755812 757523 1 755812 757523 755917 757389 orf19.7987|IPF27010.1|IPF1493.1|Contig4-3090_0048|orf6.7238|CA4647|CaO19.7987|CaO19.354|IPF1493 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 757556 758827 - orf19.355 757556 758827 1 758827 757556 758827 757556 orf19.7988|IPF27018.1|IPF1492.1|Contig4-3090_0049|orf6.7239|TCD4|CaO19.7988|CaO19.355 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 759238 760347 - orf19.356 759238 760347 2 760347|760120 760230|759238 760270 759370 GTT13 orf19.7989|IPF27039.1|IPF1491.1|Contig4-3090_0050|orf6.7240|CaO19.7989|CaO19.356 Predicted ORF in Assemblies 19, 20 and 21; opaque-specific transcription; transcription is repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 760976 761194 - ntar_593 760976 761194 1 761194 760976 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 761441 762441 + orf19.357 761441 762441 1 761441 762441 761476 762441 orf19.7990|IPF27027.1|IPF1487.2|Contig4-2361_0002|orf6.7241|PHB12|CaO19.357|CaO19.7990 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=H scenario_last_exon=H] Ca21chr3 762509 763335 - orf19.359 762509 763335 2 763335|763229 763307|762509 763335 762509 GTT12 orf19.7992|IPF27034.1|IPF1485.1|Contig4-2361_0003|orf6.7243 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 763686 763825 - ntar_594 763686 763825 1 763825 763686 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 763879 765591 + orf19.360 763879 765591 1 763879 765591 763879 765591 FUR4 orf19.7993|IPF27031.1|IPF18195.1|orf6.7244|CaO19.7993|FUR42|CaO19.360 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 765588 765896 - orf19.6957 765588 765896 1 765896 765588 765896 765588 orf19.14219|IPF20210.1|IPF27615.1|Contig4-2361_0007|orf6.7343|CaO19.14219|CaO19.6957 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 765922 767442 + orf19.6958 765922 767442 1 765922 767442 765922 767442 ECM18 orf19.14220|IPF20190.1|IPF8656.3|Contig4-3085_0034|orf6.7344|CA4720|ECM181|CaO19.6958|CaO19.14220|IPF8656.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 768399 770035 + orf19.6956 768399 770035 1 768399 770035 768458 770035 DAL9 orf19.14218|IPF20188.1|IPF8658.2|Contig4-3085_0033|orf6.7342|CA4719|DAL51|CaO19.6956|DAL52|CaO19.14218 Putative allantoate permease; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chr3 770502 772080 + orf19.6955 770502 772080 1 770502 772080 770523 771923 HBR3 orf19.14217|IPF20192.1|IPF8661.1|Contig4-3085_0030|Contig4-3085_0031|orf6.7341|CA4718|CaO19.14217|NOB1|CaO19.6955|IPF8661 Essential, uncharacterized protein; regulated by hemoglobin; S. cerevisiae ortholog is essential [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 772136 774264 + orf19.6953 772136 774264 1 772136 774264 772176 774092 IRS4 orf19.14215|IPF20183.1|IPF8663.2|Contig4-3085_0029|orf6.7339|CA4717|CaO19.14215|CaO19.6953|IPF8663 Protein with roles in cell wall integrity, systemic (but not oral) murine infection, adherence, hyphal growth, and agar-embedded filamentous growth; antigenic in human infection; similar to S. cerevisiae Irs4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 774438 776912 + orf19.6952 774438 776912 1 774438 776912 774619 776628 orf19.14214|IPF8666|IPF19384.2|IPF8666.2|Contig4-3085_0025|orf6.231|orf6.7338|CA4716|HDA2|CaO19.6952 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 777271 779398 + orf19.6951 777271 779398 1 777271 779398 777436 779205 orf19.14213|IPF19383.2|IPF16613.2|Contig4-3085_0023|orf6.232|orf6.7337|CA4715|DPL1|CaO19.6951 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 779563 780900 + orf19.6950 779563 780900 1 779563 780900 779809 780816 orf19.14212|IPF5912|IPF20198.1|IPF5912.2|Contig4-3085_0022|orf6.7336|CA4714|CaO19.6950|CaO19.14212 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=G scenario_last_exon=G] Ca21chr3 781763 782264 + ntar_595 781763 782264 1 781763 782264 781939 782100 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 782029 782355 - orf19.6949 782029 782355 1 782355 782029 782355 782029 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 782489 784183 + orf19.6948 782489 784183 1 782489 784183 782740 783678 CCC1 orf19.14210|IPF20199.1|IPF5909.2|Contig4-3085_0020|orf6.7334|CA4713|CaO19.14210|CaO19.6948 Putative manganese transporter, required for normal filamentous growth; mRNA binds to She3p and is localized to hyphal tips; repressed by nitric oxide and alkaline pH; shows colony morphology-related regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 784703 785635 + orf19.6947 784703 785635 2 784703|784915 784837|785635 784809 785635 GTT11 orf19.14209|IPF20202.1|IPF5904.1|Contig4-3085_0018|orf6.7333|CA4712|GTT1|GTT1.3 Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide [label_first_exon=CGDmod label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 785703 786650 - orf19.6944 785703 786650 1 786650 785703 786554 785703 PHB1 orf19.14206|IPF20201.1|IPF5903.1|Contig4-3085_0017|orf6.7330|CA4711|CaO19.6944|PHB11|CaO19.14206 Protein described as prohibitin; identified in detergent-resistant membrane fraction (possible lipid raft component); predicted N-terminal acetylation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chr3 787030 787738 + orf19.6943 787030 787738 1 787030 787738 787179 787508 orf19.14205|orf6.7329|CaO19.6943|CaO19.14205 Predicted ORF from Assembly 19; removed from Assembly 20; subsequently reinstated in Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 787513 789784 - orf19.6942 787513 789784 1 789784 787513 789659 787611 ORC3 orf19.14204|IPF20182.1|IPF5897.1|Contig4-3085_0013|Contig4-3085_0014|orf6.7328|CA4710|CaO19.14204|CaO19.6942 Protein similar to S. cerevisiae Orc3p, which is a component of the origin recognition complex involved in DNA replication; mutation confers hypersensitivity to toxic ergosterol analog; induced under hydroxyurea treatment [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 790151 790643 + ntar_596 790151 790643 1 790151 790643 790448 790576 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 791364 793585 + orf19.6941 791364 793585 1 791364 793585 791735 793468 orf19.14203|IPF20184.1|IPF5895.1|Contig4-3085_0010|orf6.7327|CA4709|DGA2|CaO19.14203|CaO19.6941|IPF5895 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 793350 794557 - ntar_597 793350 794557 1 794557 793350 794436 793570 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 794015 794455 + orf19.6940 794015 794455 1 794015 794455 794015 794455 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 794740 796189 + orf19.6938 794740 796189 1 794740 796189 794875 795909 MEU1 orf19.14200|IPF20196.1|IPF5890.2|Contig4-3085_0005|Contig4-3085_0007|orf6.7324|CA4708|CaO19.6938|CaO19.14200 Predicted ORF in Assemblies 19, 20 and 21;protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 797752 799619 + orf19.6937 797752 799619 1 797752 799619 797830 799560 PTR2 orf19.14199|IPF20186.1|IPF4202.2|Contig4-3085_0002|orf6.7323|CA4707|PTR22|CaO19.14199|CaO19.6937|PTR21 Putative oligopeptide transporter; regulated by Stp2p and Stp3p; transcriptionally induced upon phagocytosis by macrophage; downregulated by Rim101p at pH 8 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 799957 802227 + orf19.6936 799957 802227 1 799957 802227 800059 802158 RAD53 orf19.14198|IPF20181.1|IPF4205.1|Contig4-2365_0011|orf6.7322|CA4706|CaO19.6936|CaO19.14198 Protein involved in regulation of DNA-damage-induced filamentous growth; putative component of cell cycle checkpoint; ortholog of S. cerevisiae Rad53p, protein kinase required for cell-cycle arrest in response to DNA damage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 802135 803443 - orf19.6934 802135 803443 1 803443 802135 803414 802215 orf19.14196|IPF20193.1|IPF4206.1|Contig4-2365_0002|orf6.7320|CA4705|PNT1|CaO19.6934|CaO19.14196|IPF4206 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 803506 805044 + orf19.6933 803506 805044 1 803506 805044 803538 804614 orf19.14195|IPF20194.1|IPF4207.2|Contig4-2365_0003|orf6.7319|CA4704|CaO19.14195|RRD2|CaO19.6933 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 804305 806101 - orf19.6931 804305 806101 1 806101 804305 806089 804620 orf19.14193|IPF20191.1|IPF4212.2|Contig4-2365_0004|Contig4-2365_0005|Contig4-2365_0007|orf6.7317|CA4703|CLP1|CaO19.6931|CaO19.14193 Putative protein of unknown function; heterozygous null mutant exhibits hypersensitivity to parnafungin and cordycepin in the C. albicans fitness test; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 806229 807164 - orf19.6930 806229 807164 1 807164 806229 807026 806310 SOL1 orf19.14192|IPF20203.1|IPF4213.2|Contig4-2365_0008|orf6.7316|CA4702|CaO19.14192|SIC1|CaO19.6930|IPF4213 Cell cycle regulator; partial functional homolog of S. cerevisiae Sic1p; protein degradation regulated by SCF(CDC4) pathway; CDK phosphorylation predicted; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 807855 808605 + orf19.6929 807855 808605 1 807855 808605 807893 808420 orf19.14191|IPF20205.1|IPF4214.2|Contig4-2390_0002|orf6.7315|CA4701|CaO19.6929|CaO19.14191|IPF4214 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 808527 810483 - orf19.6928 808527 810483 1 810483 808527 810379 808745 SAP9 orf19.14190|IPF20187.1|IPF4215.2|Contig4-2390_0003|orf6.7314|CA4700|YPS1|CaO19.14190|CaO19.6928 Secreted aspartyl proteinase; roles in adhesion, cell surface integrity; induced by antifungal drugs, stationary phase, or in white-phase cells; farnesol-downregulated in biofilm; autocatalytic processing; GPI-anchor; N-glycosylated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 811407 811610 + ntar_598 811407 811610 1 811407 811610 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 811456 813167 - orf19.6927 811456 813167 1 813167 811456 812977 811934 PEP8 orf19.14189|IPF20195.1|IPF4220.1|Contig4-2390_0008|orf6.7313|CA4699|CaO19.14189|CaO19.6927|IPF4220 Protein similar to S. cerevisiae Pep8p, which is involved in retrograde transport; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 813337 817870 + orf19.6926 813337 817870 1 813337 817870 813708 817709 CSC25 orf19.14188|CDC25|IPF20209.1|IPF4222.2|orf6.7312|CA4698|CaO19.6926|CaO19.14188 Guanyl-nucleotide exchange factor; activator of Ras/adenylyl cyclase pathway; functional homolog of S. cerevisiae Cdc25p; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 817739 818516 - orf19.6925 817739 818516 1 818516 817739 818354 817962 HTB1 orf19.14187|IPF20208.1|IPF4223.1|orf6.7311|CA4697|CaO19.14187|CaO19.6925 Putative histone H2B; induced upon adherence to polystyrene; amphotericin B or caspofungin repressed; flucytosine or fluconazole induced; regulated by Efg1p; slow growth, increased white-to opaque switching in ectopic expression strains [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 818690 819417 + orf19.6924 818690 819417 1 818690 819417 818899 819297 HTA1 orf19.14186|IPF20206.1|IPF4226.2|Contig4-2902_0018|orf6.7310|CA4696|CaO19.6924|CaO19.14186 Putative histone H2A; reduced mRNA abundance detected in homozygous fkh2 null mutant; amphotericin B repressed; farnesol regulated; RNA abundance regulated by tyrosol and cell density [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 819562 819777 + orf19.6923.1 819562 819777 1 819562 819777 819562 819777 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 819835 821320 + orf19.6923 819835 821320 1 819835 821320 819835 820866 orf19.14185|IPF20197.1|IPF4229.2|Contig4-2902_0016|orf6.7309|CA4695|TAF11|CaO19.6923|IPF4229 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 822246 822374 - orf19.2813 822246 822374 1 822374 822246 822374 822246 orf19.10331|IPF24535.1|IPF3539.2|Contig4-3051_0001|orf6.4580|CA2617|CaO19.2813|CaO19.10331|IPF3539 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 826161 826250 + orf19.6922 826161 826250 1 826161 826250 orf19.14184|IPF20211.1|IPF18180.2|orf6.7308 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 826452 828102 - orf19.2812 826452 828102 1 828102 826452 828102 826591 orf19.10330|IPF24531.1|IPF19762.1|Contig4-1935_0004|orf6.4581|CA2618|SNG1|CaO19.2812|CaO19.10330|SNG2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr3 828675 830588 - orf19.2810 828675 830588 1 830588 828675 830588 828675 AAP1 orf19.10328|IPF24528.1|IPF9490.2|Contig4-1993_0003|orf6.4583|CA2619|CaO19.2810|GAP32|CaO19.10328|IPF9490 Putative amino acid permease; fungal-specific (no human or murine homolog) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr3 832497 835184 - orf19.2809 832497 835184 1 835184 832497 835184 832506 CTN3 orf19.10327|CAT3|IPF24526.1|IPF9496.1|Contig4-2893_0003|orf6.4584|CA2620|YAT2|CaO19.10327|CaO19.2809|IPF9496 Predicted peroxisomal carnitine acetyl transferase; Ura+ deletion strain has no obvious metabolic, hyphal, or virulence defects; transcription induced by macrophage engulfment, hyphal growth, starvation, or nonfermentable carbon sources [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr3 835798 835894 - te(uuc)6 835798 835894 2 835894|835832 835858|835798 tE(UUC)6.2 tRNA-Glu predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 836139 839513 - orf19.2808 836139 839513 1 839513 836139 839513 836277 ZCF16|orf19.10326|CAT8|IPF24542.1|IPF9499.2|Contig4-2893_0005|Contig4-2893_0006|orf6.4585|CA2621|CaO19.10326|CaO19.2808|IPF9499 Predicted zinc-finger protein of unknown function, not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr3 839801 839938 - ntar_599 839801 839938 1 839938 839801 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 840905 843753 - orf19.2805 840905 843753 1 843753 840905 843670 841187 orf19.10323|orf19.10324|IPF19631.1|IPF24534.1|IPF19632.2|IPF11531.2|Contig4-2893_0007|Contig4-2893_0010|orf6.1492|orf6.4587|orf6.4588|CA2623|CA2622|orf19.2806|PER3.5f|PER3.exon1 Predicted ORF in Assemblies 19, 20 and 21; expression regulated during planktonic growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr3 844496 845455 + orf19.2804 844496 845455 2 844496|844760 844666|845455 844496 845455 orf19.10322|IPF24538.1|IPF11526.2|Contig4-2893_0012|orf6.1493|orf6.4589|CA0516|CaO19.2804|IPF11526 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 845759 845831 + ta(agc)2 845759 845831 1 845759 845831 tA(AGC)2.2 tRNA-Ala predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 846055 847597 - orf19.2803 846055 847597 1 847597 846055 847277 846306 HEM13 orf19.10321|orf6.1494|IPF24536.1|IPF11525.2|Contig4-2893_0015|CA0517|CaO19.2803|CaO19.10321 Coproporphyrinogen III oxidase; antigenic in human, mouse; localizes to yeast-form cell surface, not hyphae; soluble in hyphae; iron-regulated expression; macrophage-downregulated protein; not Rfg1p regulated, farnesol-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 848629 853315 - orf19.918 848629 853315 1 853315 848629 853315 848777 CDR11 orf19.8533|orf19.8534|orf19.10320|CDR2|Contig4-2585_0004|IPF24540.1|IPF11524.1|IPF12975.1|IPF26378.1|IPF29637.1|Contig4-2585_0001|Contig4-2893_0020|orf6.1644|orf6.1495|CDR5|CDR99|CA0518|CA0610|CA0609|orf19.919|orf19.2802|PDR10|CDR11.5f Putative transporter of PDR subfamily of ABC family; Gcn4p-regulated; upregulated by Rim101p at pH 8 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr3 854779 855950 + orf19.913.2 854779 855950 2 854779|855234 855114|855950 855058 855584 IPF12970.3|IPF16430.1|CA0118|IPF16430|IPF16430.3 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 856688 858208 + orf19.5854 856688 858208 1 856688 858208 856951 857799 SBP1 orf19.13276|IPF19078.2|IPF10692.2|Contig4-2525_0004|orf6.5046|CA2951|CaO19.13276|CaO19.5854|CA0252|SBP1.5eoc|IPF19078.1 Similar to RNA binding proteins; downregulated upon adherence to polystyrene; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 858422 859327 + orf19.5854.1 858422 859327 1 858422 859327 858794 859273 IPF21174.1|IPF21316.1|IPF19670.1|IPF19671.1|Contig4-2525_0005|CA2952|IPF19671 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 859231 862275 - orf19.5855 859231 862275 1 862275 859231 861887 859329 MBP1 orf19.13277|IPF21163.1|IPF10688.2|Contig4-2525_0008|orf6.5047|CA2953|CaO19.5855|CaO19.13277 Predicted ORF in Assemblies 19, 20 and 21; non-periodic mRNA expression; predicted, conserved MBF binding sites upstream of G1/S-regulated genes [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 862501 863688 - orf19.5856 862501 863688 1 863688 862501 863515 862553 orf19.13278|IPF21237.1|IPF10685.2|Contig4-2525_0011|orf6.5048|CA2954|CaO19.13278|CaO19.5856|IPF10685 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 862854 863255 + ntar_600 862854 863255 1 862854 863255 862854 863063 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 863841 865201 + orf19.5857 863841 865201 1 863841 865201 864047 865081 orf19.13279|IPF21235.1|IPF15201.2|Contig4-2168_0001|orf6.5049|CA2955|CaO19.5857|CaO19.13279|IPF15201 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 865077 865734 - orf19.5858 865077 865734 1 865734 865077 865680 865144 EGD2 orf19.13280|IPF21270.1|IPF15200.1|Contig4-2168_0002|orf6.5050|CA2956|CaO19.5858|CaO19.13280 Predicted ORF in Assemblies 19, 20 and 21; soluble protein in hyphae; macrophage/pseudohyphal-induced; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 866094 866444 + ntar_601 866094 866444 1 866094 866444 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 867155 868735 + orf19.5859 867155 868735 1 867155 868735 867155 868735 DAL8 orf19.13281|IPF21202.1|IPF8598.2|Contig4-1908_0004|orf6.5051|CA2957|DAL53|CaO19.5859 Putative allantoate permease; fungal-specific (no human or murine homolog) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 867209 867768 - ntar_602 867209 867768 1 867768 867209 867510 867229 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 869598 870084 + orf19.5860 869598 870084 1 869598 870084 869680 870084 orf19.13282|orf6.5052|CaO19.13282|CaO19.5860 Predicted ORF from Assembly 19; removed from Assembly 20; subsequently reinstated in Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 870370 871746 + orf19.5861 870370 871746 1 870370 871746 870661 871476 KRE9 orf19.13283|IPF21251.1|IPF8595.2|Contig4-2845_0003|orf6.5053|CA2958|CaO19.5861|CaO19.13283 Protein of beta-1,6-glucan biosynthesis; required for serum-induced hyphal growth; required for efficient utilization of galactose and for growth on glucose; similar to S. cerevisiae Kre9p and Knh1p; O-glycosylated by Pmt1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 871922 872608 + orf19.5861.1 871922 872608 1 871922 872608 872170 872460 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 872676 874214 + orf19.5862 872676 874214 1 872676 874214 872760 874016 orf19.13284|IPF21223.1|IPF8591.1|Contig4-2845_0007|orf6.5054|CA2959|AFP99|CaO19.5862|CaO19.13284|IPF8591 Protein described as related to arginases; downregulated upon adherence to polystyrene; regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 874905 875423 + orf19.5863 874905 875423 1 874905 875423 874905 875423 orf19.13285|IPF21267.1|IPF8590.1|Contig4-2845_0009|orf6.5055|CA2960|CaO19.5863|IPF8590 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 875534 877474 - orf19.5864 875534 877474 1 877474 875534 877331 875694 URK1 orf19.13286|IPF21197.1|IPF8589.1|Contig4-2845_0010|Contig4-2845_0011|orf6.5056|CA2961|CaO19.5864|CaO19.13286 Protein described as similar to uridine kinase; transcription is downregulated in response to treatment with ciclopirox olamine [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 877575 880216 + orf19.5865 877575 880216 1 877575 880216 877619 880216 orf19.13287|IPF21159.1|IPF8587.2|Contig4-2845_0013|orf6.1040|orf6.5057|CA2962|PRP2|CaO19.13287|CaO19.5865 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr3 881431 881754 - orf19.5866 881431 881754 1 881754 881431 881754 881431 orf19.13288|IPF21337.1|IPF27893.1|orf6.1041|orf6.5058|CaO19.5866 [NOT TRANSCRIBED?] Protein not essential for viability [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 882603 884635 + orf19.5867 882603 884635 1 882603 884635 883133 884209 WSC1 orf19.13289|IPF15153.1|IPF8580.2|Contig4-2845_0017|orf6.1042|orf6.5059|CA0274|CaO19.5867|WSC3|IPF15153|CA0244|IPF19082|IPF19082.1 Protein described as a cell wall component; increased mRNA abundance observed in cyr1 homozygous null mutant (yeast-form or hyphal cells) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 885058 886908 + orf19.5869 885058 886908 2 885058|885616 885326|886908 885309 886872 orf19.13290|IPF18047.2|IPF15266.1|Contig4-1864_0002|orf6.9168|orf6.970|CA0243|BSD2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 887034 888111 - orf19.5870 887034 888111 2 888111|887962 888034|887034 888048 887093 CTP1 orf19.13291|IPF18048.1|IPF15267.1|Contig4-1864_0004|orf6.9167|orf6.969|CA6166|CTP1.3f Predicted ORF in Assemblies 19, 20 and 21; flucytosine induced; amphotericin B repressed, caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 890972 893083 - orf19.5871 890972 893083 1 893083 890972 893062 890972 orf19.13292|orf19.13293|orf6.774|IPF19844.2|IPF21275.1|IPF14343.2|IPF14342.2|Contig4-3084_0009|Contig4-3084_0010|Contig4-3084_0011|orf6.9166|orf6.9165|CA6165|CA6164|orf19.5872|SNF5.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr3 893256 897858 - orf19.5873 893256 897858 1 897858 893256 897766 893354 POL1 orf19.13294|IPF21292.1|IPF1832.2|Contig4-3084_0013|orf6.9164|CA6163|CaO19.13294|CaO19.5873 Protein described as DNA directed DNA polymerase alpha; RNA abundance regulated by cell cycle, tyrosol and cell density [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 898214 899104 - orf19.5874 898214 899104 1 899104 898214 899104 898214 orf19.13295|IPF21240.1|IPF1833.2|Contig4-3084_0014|orf6.9163|CA6162|CaO19.5874|CaO19.13295|IPF1833 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 899568 900556 + orf19.5875 899568 900556 1 899568 900556 899622 900482 VAM3 orf19.13296|IPF21246.1|IPF1834.2|Contig4-3084_0015|orf6.9162|CA6161|CaO19.13296|PEP12|CaO19.5875|IPF1834 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 900396 901608 - orf19.5876 900396 901608 2 901608|901010 901074|900396 901086 900631 orf19.13297|IPF21273.1|IPF1835.1|Contig4-3084_0016|orf6.9161|CA6160|CaO19.13297|CaO19.5876|IPF1835 Predicted ORF in Assemblies 19, 20 and 21; greater mRNA abundance observed in a cyr1 homozygous null mutant than in wild type; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 901418 901620 + ntar_603 901418 901620 1 901418 901620 901420 901569 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 901721 904148 + orf19.5877 901721 904148 1 901721 904148 901890 903368 ATF1 orf19.13298|IPF21208.1|IPF1837.2|Contig4-3084_0018|orf6.9160|CA6159|CaO19.5877|CaO19.13298|IPF1837 Putative alcohol acetyltransferase; caspofungin repressed; expression depends on Tac1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 903496 904465 - orf19.5879 903496 904465 1 904465 903496 904465 903572 orf19.13300|IPF21243.1|IPF1839.2|Contig4-3084_0019|orf6.9158|CA6158|AYR3|CaO19.5879|CaO19.13300|IPF1839 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr3 904930 905095 - ntar_604 904930 905095 1 905095 904930 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 905204 907648 + orf19.5880 905204 907648 1 905204 907648 905228 907534 orf19.13301|orf19.13302|IPF21249.1|IPF21205.1|IPF1844.1|IPF1841.1|Contig4-3084_0022|Contig4-3084_0024|orf6.9156|orf6.9157|CA6157|CA6156|orf19.5881|GEF1.5f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 907392 911008 - orf19.5884 907392 911008 1 911008 907392 910944 907582 orf19.13305|IPF21326.1|IPF1846.1|Contig4-3084_0026|orf6.9153|CA6155|URB2|CaO19.13305|CaO19.5884|IPF1846 Predicted ORF in Assemblies 19, 20 and 21; decreased transcription is observed upon benomyl treatment or in an azole-resistant strain that overexpresses MDR1 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 911136 911768 - orf19.5885 911136 911768 1 911768 911136 911645 911265 orf19.13306|IPF21311.1|IPF1848.1|Contig4-3084_0029|orf6.9152|CA6154|SNU13|CaO19.13306|CaO19.5885|IPF1848 Predicted ORF in Assemblies 19, 20 and 21; flucytosine induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 912072 913213 + orf19.5886 912072 913213 2 912072|912446 912147|913213 912134 912914 CUP5 orf19.13307|IPF21283.1|IPF1849.1|Contig4-3084_0032|orf6.9151|CA6153 Predicted ORF in Assemblies 19, 20 and 21; caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 913051 915578 - orf19.5887 913051 915578 1 915578 913051 915538 913217 NUP85 orf19.13308|IPF21170.1|IPF1850.1|Contig4-3084_0033|orf6.9150|CA6152|CaO19.5887|CaO19.13308 Protein not essential for viability; similar to S. cerevisiae Nup85p, which is a subunit of the nuclear pore complex [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 915666 919198 - orf19.5890 915666 919198 1 919198 915666 919036 915701 orf19.13311|IPF21331.1|IPF1853.1|Contig4-3084_0036|orf6.9147|CA6151|CaO19.13311|CaO19.5890|IPF1853 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 919451 922454 + orf19.5892 919451 922454 1 919451 922454 919710 922394 orf19.13310|orf19.13312|orf19.13313|IPF21155.1|IPF1857.2|Contig4-3084_0038|Contig4-3084_0040|Contig4-3084_0041|orf6.9148|orf6.9146|orf6.9145|CA6150|orf19.5889|orf19.5891|IPF1857 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 922659 923825 + orf19.5893 922659 923825 2 922659|922939 922769|923825 922721 923531 RIP1 orf19.13314|orf6.9144|IPF21263.1|IPF1859.1|Contig4-3084_0044|CA6149 Protein described as subunit of ubiquinol cytochrome c-reductase; transcriptionally regulated by iron; expression greater in high iron; alkaline downregulated; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 923829 925533 - orf19.5894 923829 925533 2 925533|925041 925118|923829 925533 923829 orf19.13315|orf19.13316|IPF21290.1|IPF21225.1|IPF1862.1|IPF1861.2|Contig4-3084_0047|Contig4-3084_0048|orf6.9143|orf6.9142|CA6148|CA6147|orf19.5895|IPF1862.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 925735 926574 - orf19.5896 925735 926574 1 926574 925735 926574 925735 orf19.13317|IPF21247.1|IPF1863.1|orf6.9141|CA6146|CaO19.5896|CaO19.13317|IPF1863 Predicted ORF in Assemblies 19, 20 and 21; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 927405 930577 + orf19.5897 927405 930577 1 927405 930577 927454 930447 orf19.13318|IPF21351.1|IPF1869.1|Contig4-2395_0003|Contig4-2395_0004|orf6.9140|CA6145|CaO19.5897|CaO19.13318|IPF1869 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 930933 934541 + orf19.5901 930933 934541 1 930933 934541 931122 934415 PKC1 orf19.13322|IPF21335.1|IPF1872.1|Contig4-2395_0002|Contig4-2874_0014|orf6.9136|CA6144|CaO19.13322|CaO19.5901 Protein kinase C; functional homolog of S. cerevisiae Pkc1p; mutant has abnormal yeast-form cell morphology and increased cell lysis; activated by phosphatidylserine; target of antifungal, cercosporamide; R400P mutant is activated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 934549 935511 - orf19.5902 934549 935511 1 935511 934549 935511 934549 RAS2 orf19.13323|IPF21239.1|IPF1873.1|Contig4-2874_0002|orf6.9135|RLP1|CA6143|CaO19.5902|CaO19.13323|IPF1873 Protein similar to S. cerevisiae Ras2p, which activates adenylate cyclase and is involved in pseudohyphal growth of S. cerevisiae; transposon mutation affects filamentous growth [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr3 938889 941275 + orf19.5903 938889 941275 1 938889 941275 939258 940910 RAX1 orf19.13324|IPF21201.1|IPF1879.1|Contig4-2874_0009|Contig4-2874_0010|orf6.9134|CA6142|CaO19.5903|CaO19.13324|IPF1879 Protein described as having a possible role in bud site selection; hyphal-induced expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 941046 942581 - orf19.5904 941046 942581 2 942581|941958 942395|941046 942396 941388 RPL19A orf19.13325|IPF21264.1|IPF1881.1|RPL19B|Contig4-2874_0011|orf6.9133|CA6141|RPL19A.3 Predicted ribosomal protein; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 942847 943557 + orf19.5905 942847 943557 1 942847 943557 942961 943263 orf19.13326|IPF21349.1|IPF1882.1|Contig4-2874_0012|orf6.9132|CA6140|CaO19.13326|CaO19.5905|IPF1882 Predicted ORF in Assemblies 19, 20 and 21; induced upon biofilm formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 943356 945300 - orf19.5906 943356 945300 1 945300 943356 945232 943526 ADE2 orf19.13327|IPF21193.1|IPF1883.1|Contig4-2874_0013|orf6.9131|CA6139|CaO19.5906|CaO19.13327 Phosphoribosylaminoimadazole carboxylase; enzyme of adenine biosynthesis; required for wild-type growth and virulence in immunosuppressed mouse systemic infection; not induced during GCN response, in contrast to S. cerevisiae ortholog [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 949718 952120 - orf19.5908 949718 952120 1 952120 949718 952103 949872 TEC1 orf19.13329|IPF21178.1|IPF4351.1|Contig4-3037_0020|orf6.9129|CA6138|CaO19.13329|CaO19.5908|IPF4351 TEA/ATTS transcription factor involved in regulation of hypha-specific genes; required for wild-type biofilm formation; regulates BCR1; directly transcriptionally regulated by Cph2p under some growth conditions; alkaline upregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 957555 960537 - orf19.5910 957555 960537 1 960537 957555 960451 958172 orf19.13331|IPF21173.1|IPF4356.2|Contig4-3037_0012|orf6.9127|CA6137|NTO1|CaO19.13331|CaO19.5910|IPF4356 Predicted ORF in Assemblies 19, 20 and 21; induced upon low-level peroxide stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 960579 961958 - orf19.5911 960579 961958 1 961958 960579 961927 960680 CMK1 orf19.13332|IPF21212.1|IPF4358.1|Contig4-3037_0009|orf6.9126|CA6135|CaO19.13332|CaO19.5911 Expression is regulated upon white-opaque switching; biochemically purified Ca2+/CaM-dependent kinase is soluble, cytosolic, monomeric, and serine-autophosphorylated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 962541 965892 + orf19.5912 962541 965892 1 962541 965892 962574 965774 MAK21 orf19.13333|IPF21339.1|IPF4362.1|Contig4-3037_0008|orf6.9125|CA6134|CaO19.5912|CaO19.13333 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to tubercidin (7-deazaadenosine) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 965866 967917 - orf19.5915 965866 967917 1 967917 965866 967917 965911 orf19.13336|orf19.13337|IPF21222.1|IPF21257.1|IPF4364.1|IPF4365.1|Contig4-3037_0006|Contig4-3037_0007|orf6.9122|orf6.9121|CA6133|CA6132|orf19.5916|DUR35.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr3 968867 970659 - orf19.5917 968867 970659 1 970659 968867 970366 969056 STP3 orf19.13338|IPF21221.1|IPF4369.1|STP1|Contig4-3037_0004|orf6.9120|CA6131|CaO19.13338|CaO19.5917|IPF4369 Transcription factor; regulates SAP2, OPT1 expression and thereby protein catabolism for nitrogen source; activated via amino-acid-induced proteolytic processing; macrophage/pseudohyphal-repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 973820 975666 + orf19.5917.3 973820 975666 2 973820|975060 974156|975666 973884 975470 IPF21354.1|IPF21308.1|IPF157.1|IPF155.1|Contig4-2225_0003|Contig4-2225_0007|CA6130|orf19.5917.5|YRA1|CA6129|YRA1.exon2 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 975556 975861 - orf19.5918 975556 975861 1 975861 975556 975861 975556 orf19.13339|IPF21342.1|IPF27895.1|orf6.9119|CaO19.5918|CaO19.13339 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 976398 978669 + orf19.5919 976398 978669 1 976398 978669 976573 978462 MEA1 orf19.13340|IPF21186.1|IPF152.2|orf6.9118|CA6128|CaO19.5919|CaO19.13340|IPF152 Protein similar to A. nidulans MesA, which is involved in localization of actin cables [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 978471 979151 - orf19.5920 978471 979151 1 979151 978471 979049 978639 orf19.13341|IPF21282.1|IPF151.1|orf6.9117|CaO19.5920|CaO19.13341 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 980300 981819 + orf19.5921 980300 981819 1 980300 981819 980600 981691 orf19.13342|IPF21230.1|IPF149.1|Contig4-2340_0001|orf6.9116|CA6127|PMP47|CaO19.5921|CaO19.13342|IPF149 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 985038 988518 + orf19.5924 985038 988518 1 985038 988518 985126 988518 ZCF31|orf19.13345|IPF21328.1|IPF143.2|Contig4-2867_0017|orf6.9113|CA6126|CaO19.5924|CaO19.13345|IPF143 Predicted zinc-finger protein of unknown function [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chr3 989009 990453 + orf19.5925 989009 990453 1 989009 990453 989158 990291 orf19.13346|IPF21228.1|IPF138.1|Contig4-2867_0014|orf6.9112|CA6125|CaO19.5925|CaO19.13346|IPF138 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 990305 991453 - orf19.5926 990305 991453 1 991453 990305 991361 990408 ARG11 orf19.13347|IPF18052.2|IPF137.1|Contig4-2867_0013|orf6.9111|CA6124|CaO19.13347|ORT1|CaO19.5926 Protein induced during the mating process [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 991525 992785 - orf19.5927 991525 992785 2 992785|992276 992652|991525 992664 991861 RPS15 orf19.13348|IPF21299.1|IPF135.1|Contig4-2867_0011|Contig4-2867_0012|orf6.9110|CA6123|RPS15.3 Putative ribosomal protein; macrophage/pseudohyphal-induced after 16 h; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 993009 993567 + orf19.5928 993009 993567 1 993009 993567 993121 993456 RPP2B orf19.13349|RP2B|CARP2B|IPF21317.1|IPF134.1|RPL45|Contig4-2867_0010|orf6.9109|CA6122|CaO19.13349|CaO19.5928 Conserved acidic ribosomal protein, likely to be involved in regulation of translation elongation; interacts with Rpp1Ap; one of four similar C. albicans ribosomal proteins (Rpp1Ap, Rpp1Bp, Rpp2Ap, Rpp2Bp); macrophage/pseudohyphal-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 993472 994670 - orf19.5929 993472 994670 1 994670 993472 994596 993574 orf19.13350|IPF21236.1|IPF133.1|Contig4-2867_0009|orf6.9108|CA6121|CaO19.5929|CaO19.13350|IPF33 Putative protein of unknown function, transcription is positively regulated by Tbf1p; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 994773 995952 + orf19.5930 994773 995952 1 994773 995952 994833 995933 orf19.13351|IPF21232.1|IPF132.1|Contig4-2867_0006|Contig4-2867_0007|orf6.9107|CA6120|CaO19.13351|NUP42|CaO19.5930|IPF132 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 996072 997513 + orf19.5931 996072 997513 1 996072 997513 996093 996983 orf19.13352|IPF21244.1|IPF128.1|Contig4-2867_0004|orf6.9106|CA6119|CaO19.13352|ARV1|CaO19.5931 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 996917 999604 - orf19.5932 996917 999604 1 999604 996917 999577 996980 orf19.13353|IPF21160.1|IPF126.2|Contig4-2867_0003|orf6.9105|CA6118|CaO19.13353|CaO19.5932|IPF126 Predicted ORF in Assemblies 19, 20 and 21; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1000200 1001627 - orf19.5933 1000200 1001627 1 1001627 1000200 1001627 1000200 orf19.13354|IPF21209.1|IPF122.1|Contig4-2867_0002|orf6.9104|CA6117|CaO19.5933|CaO19.13354|IPF122 Predicted ORF in Assemblies 19, 20 and 21; increased transcription is observed upon benomyl treatment; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1004299 1006357 - orf19.5934 1004299 1006357 1 1006357 1004299 1006283 1004394 orf19.13355|IPF21187.1|IPF116.2|Contig4-3022_0019|Contig4-3022_0020|orf6.9103|CA6116|TOP3|CaO19.13355|CaO19.5934 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1006896 1008892 + orf19.5935 1006896 1008892 1 1006896 1008892 1006978 1008810 orf19.13356|IPF21185.1|IPF112.1|Contig4-3022_0017|orf6.9102|CA6115|CaO19.5935|CaO19.13356|IPF112 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1008827 1015039 - orf19.5938 1008827 1015039 1 1015039 1008827 1014997 1008941 SEN1 orf19.13359|IPF21262.1|IPF110.1|Contig4-3022_0012|Contig4-3022_0013|Contig4-3022_0015|orf6.9099|CA6114|CaO19.13359|CaO19.5938 Predicted ORF in Assemblies 19, 20 and 21; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1015343 1017555 - orf19.5940 1015343 1017555 1 1017555 1015343 1017493 1015343 ZCF32|orf19.13361|IPF21177.1|IPF100.1|Contig4-3022_0010|Contig4-3022_0011|orf6.9097|CA6113|CaO19.5940|CaO19.13361|IPF100.3f|IPF100.3 Predicted zinc-finger protein of unknown function [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1017525 1018034 + ntar_605 1017525 1018034 1 1017525 1018034 1017525 1017647 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1017807 1019239 - orf19.5941 1017807 1019239 1 1019239 1017807 1019201 1018164 orf19.13362|IPF21234.1|IPF97.1|Contig4-3022_0009|orf6.9096|CA6112|ERV41|CaO19.5941|CaO19.13362|IPF97 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1019451 1021011 + orf19.5942 1019451 1021011 1 1019451 1021011 1019512 1020960 orf19.13363|IPF21203.1|IPF96.1|Contig4-3022_0008|orf6.9095|CA6111|CaO19.5942|CaO19.13363|IPF96 Protein described as a zinc finger protein similar to S. cerevisiae Itt1p; downregulated upon adherence to polystyrene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1020848 1022827 - orf19.5943 1020848 1022827 1 1022827 1020848 1022772 1021006 orf19.13364|IPF21194.1|IPF91.2|Contig4-3022_0006|Contig4-3022_0007|orf6.9094|CA6110|PEX28|CaO19.13364|CaO19.5943|IPF91 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1023064 1024680 - orf19.5943.1 1023064 1024680 2 1024680|1024029 1024504|1023064 1024521 1023244 IPF21254.1|IPF89.1|Contig4-3022_0004|CA6109|IPF89.3f|IPF89.3 Putative protein of unknown function, transcription is upregulated in an RHE model of oral candidiasis; ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=F] Ca21chr3 1024785 1030501 - orf19.5947 1024785 1030501 1 1030501 1024785 1030396 1024877 SEC7 orf19.13368|IPF21269.1|IPF85.1|orf6.9090|CA6108|CaO19.13368|CaO19.5947 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to Brefeldin A; caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1030652 1036439 - orf19.5949 1030652 1036439 1 1036439 1030652 1036390 1030736 FAS2 orf19.13370|orf19.13372|IPF21167.1|IPF21281.1|IPF21154.1|IPF76.2|IPF77.2|IPF80.2|Contig4-3087_0034|Contig4-3087_0035|Contig4-3087_0037|orf6.9086|orf6.9089|CA6107|CA6105|orf19.5951|FAS2.3f Alpha subunit of fatty-acid synthase; required for virulence in mouse systemic infection and rat oropharyngeal infection models; regulated by Efg1p; fluconazole-induced; amphotericin B repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1036618 1038735 + ntar_606 1036618 1038735 1 1036618 1038735 1037175 1037363 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1037369 1038685 - orf19.5952 1037369 1038685 1 1038685 1037369 1038685 1037369 orf19.13373|IPF21220.1|IPF75.1|Contig4-3087_0032|orf6.9085|CA6104|CaO19.5952|CaO19.13373|IPF65 Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide in yhb1 null mutant [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr3 1039070 1039154 - tk(cuu)2 1039070 1039154 2 1039154|1039105 1039118|1039070 tK(CUU)2.2 tRNA-Lys predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1040421 1043097 + orf19.5953 1040421 1043097 1 1040421 1043097 1041441 1042778 orf19.13374|IPF21219.1|IPF72.1|Contig4-3087_0031|orf6.9084|CA6103|SFP1|CaO19.5953|CaO19.13374 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1043687 1045307 + orf19.5954 1043687 1045307 2 1043687|1044706 1044617|1045307 1043687 1045307 orf19.13375|IPF21242.1|IPF21261.1|IPF70.1|IPF68.1|Contig4-3087_0026|Contig4-3087_0028|Contig4-3087_0029|orf6.9083|CA6102|SPO70.5f [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1045609 1046870 + orf19.5956 1045609 1046870 1 1045609 1046870 1045674 1046531 orf19.13377|IPF21250.1|IPF66.1|Contig4-3087_0025|orf6.9081|CA6100|CaO19.13377|PIN3|CaO19.5956|IPF66 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1047997 1052496 + orf19.5958 1047997 1052496 1 1047997 1052496 1047997 1052496 CDR2 orf19.13379|IPF21286.1|IPF63.1|Contig4-3087_0024|CA6099|CaO19.13379|CaO19.5958|orf6.9079 Multidrug transporter, ATP-binding cassette (ABC) superfamily; transports phospholipids, in-to-out direction; low mRNA level; overexpressed in azole-resistant isolates; expression confers multidrug resistance to S. cerevisiae pdr5 mutant [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr3 1052819 1055498 + orf19.5959 1052819 1055498 1 1052819 1055498 1052846 1055374 NOP14 orf19.13380|IPF21162.1|IPF61.1|Contig4-3087_0022|orf6.9078|CA6098|CaO19.13380|CaO19.5959|IPF61 Predicted ORF in Assemblies 19, 20 and 21; mutation confers resistance to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); heterozygous null mutant exhibits resistance to parnafungin [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1055846 1057459 - orf19.5960 1055846 1057459 1 1057459 1055846 1057274 1056762 orf19.13381|IPF21265.1|IPF59.1|Contig4-3087_0018|orf6.9077|CA6097|CaO19.5960|NCE102|CaO19.13381 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1056000 1056348 + ntar_607 1056000 1056348 1 1056000 1056348 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1058628 1058883 + ntar_608 1058628 1058883 1 1058628 1058883 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1059394 1060493 - orf19.5961 1059394 1060493 1 1060493 1059394 1060431 1059682 orf19.13382|IPF21255.1|IPF56.1|Contig4-3087_0009|orf6.9076|CA6096|CaO19.5961|NAS6|CaO19.13382|IPF56 Predicted ORF in Assemblies 19, 20 and 21; described as similar to S. cerevisiae Nas6p proteasome component; induced upon adherence to polystyrene; regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1060730 1063146 - orf19.5962 1060730 1063146 1 1063146 1060730 1063077 1060831 SNF3 orf19.13383|GSP1|HGT4|IPF21175.1|IPF55.1|Contig4-3087_0008|orf6.9075|CA6095|CaO19.5962|CaO19.13383 Glucose and galactose sensor; fermentation, filamentation, virulence roles; in 20-member C. albicans glucose transporter family, extended C terminus; high-glucose repressed; induced in macrophage, repressed in biofilm [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr3 1064202 1065528 + orf19.5963 1064202 1065528 1 1064202 1065528 1064250 1065299 orf19.13384|IPF21231.1|IPF53.2|Contig4-3087_0005|Contig4-3087_0007|orf6.9074|CA6094|CaO19.13384|CaO19.5963|IPF53 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1065460 1065710 - ntar_609 1065460 1065710 1 1065710 1065460 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1065840 1067148 + orf19.5964 1065840 1067148 1 1065840 1067148 1066237 1066782 ARF2 orf19.13385|IPF21268.1|IPF50.2|Contig4-3087_0003|orf6.9073|CA6093|CaO19.5964|CaO19.13385|ARF22 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to Brefeldin A [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1067773 1068982 + orf19.5964.2 1067773 1068982 2 1067773|1068391 1067950|1068982 1067948 1068750 RPL35 IPF21319.1|IPF47.1|Contig4-3087_0001|CA6092|RPL35.3 Protein described as a ribosomal protein; downregulation correlates with clinical development of fluconazole resistance; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1068947 1072393 - orf19.5965 1068947 1072393 1 1072393 1068947 1072236 1069009 orf19.13386|IPF21338.1|IPF46.2|Contig4-3042_0001|Contig4-3042_0002|Contig4-3042_0003|orf6.9072|CA6091|CaO19.13386|UFD2|CaO19.5965 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1072432 1073031 + orf19.5966 1072432 1073031 1 1072432 1073031 1072432 1072773 orf19.13387|IPF21294.1|IPF27869.1|orf6.9071|CaO19.5966|CaO19.13387 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1073061 1074620 + orf19.5967 1073061 1074620 1 1073061 1074620 1073192 1074424 FGR44 orf19.13388|IPF21226.1|IPF44.1|Contig4-3042_0010|orf6.9070|CA6090|CaO19.5967|CaO19.13388|IPF44 Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1074751 1074890 - ntar_610 1074751 1074890 1 1074890 1074751 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1074952 1075884 + orf19.5968 1074952 1075884 1 1074952 1075884 1075122 1075733 RDI1 orf19.13389|IPF21259.1|IPF40.1|Contig4-3042_0013|orf6.9069|CA6089|CaO19.5968|CaO19.13389 Protein similar to S. cerevisiae Rdi1p, an inhibitor of Rho-GDP dissociation; transposon mutation affects filamentous growth; farnesol-, filament-induced; regulated by Nrg1p, Tup1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1075922 1078794 - orf19.5970 1075922 1078794 1 1078794 1075922 1078753 1076165 orf19.13391|IPF21158.1|IPF37.1|HPR5|Contig4-3042_0014|Contig4-3042_0015|orf6.9067|CA6088|CaO19.13391|CaO19.5970 Protein described as a DNA repair helicase; transcriptionally induced by interaction with macrophage; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1078914 1080849 + orf19.5971 1078914 1080849 1 1078914 1080849 1078992 1080836 orf19.13392|IPF21189.1|IPF36.1|Contig4-3042_0016|orf6.9066|CA6087|CaO19.5971|CaO19.13392|YHV1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1081029 1082159 + orf19.5973 1081029 1082159 1 1081029 1082159 1081111 1082022 orf19.13394|IPF21245.1|IPF33.1|Contig4-3042_0017|orf6.9064|CA6086|CaO19.13394|PHB2|CaO19.5973 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1082022 1085202 - orf19.5974 1082022 1085202 1 1085202 1082022 1085083 1082225 ATG9 orf19.13395|IPF21152.1|IPF32.2|Contig4-3042_0018|orf6.9063|CA6085|CaO19.13395|CaO19.5974|IPF32 Protein similar to S. cerevisiae Atg9p, required for an early step in autophagy; required for cytoplasm to vacuole trafficking of Lap41p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr3 1087657 1088517 + orf19.5975 1087657 1088517 1 1087657 1088517 1087657 1088517 orf19.13396|IPF21248.1|IPF29.1|Contig4-3042_0024|orf6.9062|CA6084|CaO19.5975|CaO19.13396|IPF29 Putative transcription factor with zinc finger DNA-binding motif; fluconazole-downregulated; expression regulated during planktonic growth; increased expression observed in an ssr1 homozygous null mutant [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1088861 1089875 - ntar_611 1088861 1089875 1 1089875 1088861 1089017 1088892 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1089937 1091345 + orf19.5976 1089937 1091345 1 1089937 1091345 1090005 1091345 orf19.13397|IPF21218.1|IPF26.1|IPF26|Contig4-3042_0027|orf6.9061|CA6083|CaO19.5976|CaO19.13397 Predicted ORF in Assemblies 19, 20 and 21; decreased transcription is observed upon fluphenazine treatment, in azole-resistant strains that overexpress CDR1 and CDR2 or MDR1 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1091394 1092719 + orf19.5977 1091394 1092719 1 1091394 1092719 1091394 1092719 CEM1 orf19.13398|IPF21215.1|IPF25.1|Contig4-3042_0029|orf6.9060|CA6082|CaO19.5977|CaO19.13398 Protein likely to be essential for growth, based on an insertional mutagenesis strategy; similar to S. cerevisiae Cem1p, which is an acyl carrier protein involved in fatty acid biosynthesis [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1093298 1094512 + orf19.5978 1093298 1094512 1 1093298 1094512 1093298 1094512 orf19.13399|IPF21217.1|IPF24.1|Contig4-3042_0030|Contig4-3042_0031|orf6.9059|CA6081|FZD6|CaO19.13399|CaO19.5978|IPF24 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1093507 1094400 - ntar_612 1093507 1094400 1 1094400 1093507 1094400 1094083 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1094419 1096285 - orf19.5980 1094419 1096285 1 1096285 1094419 1096285 1094555 orf19.13401|IPF21196.1|IPF21.1|Contig4-3042_0033|orf6.9057|CA6080|CaO19.5980|CaO19.13401|IPF21 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1096665 1097777 - orf19.5982 1096665 1097777 2 1097777|1097113 1097573|1096665 1097684 1096665 RPL18 orf19.13403|IPF21165.1|IPF21278.1|IPF18.1|IPF20.1|RPL18B|Contig4-3042_0035|orf6.9055|orf19.5981.1|CA6079|RPL18.exon2 Predicted ribosomal protein; Plc1p-regulated, Tbf1p-activated; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1098005 1099176 + orf19.5984 1098005 1099176 1 1098005 1099176 1098034 1099035 orf19.13405|IPF21238.1|IPF16.1|Contig4-2427_0007|orf6.9053|CA6077|CaO19.13405|CaO19.5984|IPF16 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1098976 1099781 - orf19.5985 1098976 1099781 2 1099781|1099654 1099709|1098976 1099725 1099114 orf19.13406|IPF21271.1|IPF15.1|Contig4-2427_0006|orf6.9052|CA6076|PAC10|PAC10.3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1099944 1101064 - orf19.5986 1099944 1101064 1 1101064 1099944 1101010 1099946 THI4 orf19.13407|IPF21233.1|IPF14.1|Contig4-2427_0005|orf6.9051|CA6075|CaO19.13407|CaO19.5986 Protein repressed during the mating process; fungal-specific (no human or murine homolog); protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1101244 1102834 - orf19.5987 1101244 1102834 1 1102834 1101244 1102834 1101416 orf19.13408|IPF21213.1|IPF11.1|Contig4-2427_0004|orf6.9050|CA6074|CaO19.13408|CaO19.5987|IPF11 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr3 1103379 1105025 + orf19.5989 1103379 1105025 1 1103379 1105025 1103545 1104972 orf19.13410|IPF21211.1|IPF9.2|Contig4-2512_0006|orf6.9048|CA6073|HRP1|CaO19.13410|CaO19.5989 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1105020 1107812 - orf19.5991 1105020 1107812 1 1107812 1105020 1107793 1105067 orf19.13412|IPF21153.1|IPF6.1|Contig4-2512_0001|orf6.9046|CA6072|DBP10|CaO19.5991|CaO19.13412 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1108041 1108311 + ntar_613 1108041 1108311 1 1108041 1108311 1108041 1108217 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1118600 1120245 + orf19.5992 1118600 1120245 1 1118600 1120245 1118835 1120175 WOR2 orf19.13413|IPF21214.1|IPF4835.1|Contig4-2837_0008|orf6.9045|CA6071|ZCF33|CaO19.13413|CaO19.5992|IPF4835 Transcriptional regulator of white-opaque switching; required for maintenance of opaque state [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1121988 1122247 + ntar_614 1121988 1122247 1 1121988 1122247 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1122211 1122426 - ntar_615 1122211 1122426 1 1122426 1122211 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1122436 1122731 + ntar_616 1122436 1122731 1 1122436 1122731 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1123341 1123794 - ntar_617 1123341 1123794 1 1123794 1123341 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1124932 1125309 - ntar_618 1124932 1125309 1 1125309 1124932 1125276 1125139 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1126211 1127520 + orf19.5994 1126211 1127520 1 1126211 1127520 1126578 1127132 RHB1 orf19.13415|IPF21266.1|IPF4842.1|Contig4-2771_0004|orf6.9043|CA6070|CaO19.5994|CaO19.13415|IPF4842 Putative small G protein from the Ras superfamily involved in cell wall integrity and control of filamentous growth under nitrogen starvation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1127390 1128973 - orf19.5995 1127390 1128973 1 1128973 1127390 1128919 1127573 MCA1 orf19.13416|IPF21216.1|IPF4847.1|Contig4-2771_0005|orf6.9042|CA6069|CaO19.5995|CaO19.13416|IPF4847 Putative cysteine protease with similarity to S. cerevisiae Mca1p; has a role in apoptotic cell death upon H2O2 treatment; fungal-specific (no human or murine homolog); farnesol-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1129609 1130004 - ntar_619 1129609 1130004 1 1130004 1129609 1129887 1129750 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1130330 1131425 + orf19.5996.1 1130330 1131425 2 1130330|1130749 1130381|1131425 1130362 1131166 RPS19A IPF21287.1|IPF4849.1|Contig4-2771_0008|CA6068|RPS19A.3 Putative ribosomal protein; ORF Predicted by Annotation Working Group; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1131321 1143881 - orf19.5999 1131321 1143881 1 1143881 1131321 1143881 1131396 DYN1 orf19.13420|IPF21224.1|IPF19819.1|Contig4-2771_0009|orf6.9038|CA6067|CaO19.13420|CaO19.5999 Dynein heavy chain; dynein is a motor protein that moves toward the microtubule minus end; required for wild-type yeast-form cell separation, spindle positioning, nuclear migration, hyphal growth; transcription is regulated by Mig1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr3 1146080 1150790 + orf19.6000 1146080 1150790 1 1146080 1150790 1146155 1150660 CDR1 orf19.13421|IPF21285.1|IPF9739.2|Contig4-1997_0005|CA6066|CaO19.6000|CaO19.13421|orf6.9037 Multidrug transporter of ATP-binding cassette (ABC) superfamily; transports phospholipids in an in-to-out direction; transcription induced by beta-estradiol, progesterone, corticosteroid, or cholesterol [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr3 1151761 1152957 + orf19.6001 1151761 1152957 1 1151761 1152957 1151761 1152957 SAP3 orf19.13422|IPF21229.1|IPF8313.1|Contig4-1997_0001|orf6.9036|CA6065|CaO19.6001|CaO19.13422 Secreted aspartyl proteinase; acts in utilization of protein as nitrogen source; virulence role in mouse, guinea pig systemic infection or rat vagina; regulated by growth phase; produced by opaque phase cells; alpha-pheromone repressed [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1151852 1152169 - ntar_620 1151852 1152169 1 1152169 1151852 1152169 1152023 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1153151 1154108 - orf19.6002 1153151 1154108 1 1154108 1153151 1154044 1153256 RPL8B orf19.13423|RPL81|IPF21253.1|IPF8312.2|RPL8B-1|Contig4-1997_0002|orf6.9035|CA6064|CaO19.6002|CaO19.13423 Predicted ribosomal protein; transcription is regulated upon yeast-hyphal switch; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1154319 1156379 - orf19.6003 1154319 1156379 1 1156379 1154319 1156318 1154531 orf19.13424|IPF21190.1|IPF8311.1|Contig4-1997_0004|Contig4-2656_0014|orf6.9034|CA6063|CaO19.6003|CaO19.13424|IPF8311 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1156599 1157022 - ntar_621 1156599 1157022 1 1157022 1156599 1157022 1156867 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1157561 1157884 - ntar_622 1157561 1157884 1 1157884 1157561 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1157837 1158001 + ntar_623 1157837 1158001 1 1157837 1158001 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1158445 1161017 - orf19.6005 1158445 1161017 1 1161017 1158445 1160820 1158586 HGT5 orf19.13426|IPF21176.1|IPF8307.1|Contig4-2656_0009|orf6.9032|CA6062|CaO19.13426|STL98|CaO19.6005|IPF8307 Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments, extended N terminus; expressed in rich medium with 2% glucose [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1161417 1163394 - orf19.6007 1161417 1163394 1 1163394 1161417 1162682 1161621 orf19.13428|IPF21227.1|IPF8302.1|Contig4-2656_0006|orf6.9030|CA6061|CaO19.13428|CaO19.6007|IPF8302 Predicted ORF in Assemblies 19, 20 and 21; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1163504 1164056 + ntar_624 1163504 1164056 1 1163504 1164056 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1163889 1167091 - orf19.6008 1163889 1167091 1 1167091 1163889 1166752 1163927 orf19.13429|IPF21151.1|IPF8301.2|Contig4-2656_0001|orf6.9029|CA6060|CaO19.6008|CaO19.13429|IPF8301 Predicted ORF in Assemblies 19, 20 and 21; transcription is repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr3 1167962 1168303 + ntar_625 1167962 1168303 1 1167962 1168303 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1168250 1170279 - orf19.6966 1168250 1170279 1 1170279 1168250 1170279 1168411 IPF11120.1|Contig4-2580_0006|orf6.7712|CA5014|CaO19.6966|CKI1|IPF11120 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr3 1170684 1175074 + orf19.6967 1170684 1175074 1 1170684 1175074 1171433 1174825 USO6 IPF11118.1|Contig4-2580_0004|orf6.7713|CA5015|CaO19.6967|IPF11118 Transcription is induced upon filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1177242 1177811 - ntar_626 1177242 1177811 1 1177811 1177242 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1177418 1177815 + ntar_627 1177418 1177815 1 1177418 1177815 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1178233 1181932 + orf19.6968 1178233 1181932 1 1178233 1181932 1178348 1181809 IPF7561.2|Contig4-2973_0020|orf6.7714|CA5016|CaO19.6968|IPF7561 Predicted ORF in Assemblies 19, 20 and 21; Hog1p-downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1181828 1183020 - orf19.6970 1181828 1183020 1 1183020 1181828 1182953 1181982 IPF7559|IPF7559.2|Contig4-2973_0019|orf6.7716|CA5017|CaO19.6970 Protein not essential for viability; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1183201 1184648 + orf19.6971 1183201 1184648 1 1183201 1184648 1183259 1184611 DIE2 IPF7558.1|Contig4-2973_0017|orf6.7717|CA5018|CaO19.6971|IPF7558 Protein not essential for viability; similar to S. cerevisiae Die2p, which is dolichyl-phosphoglucose-dependent glucosyltransferase involved in protein N-glycosylation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1184578 1186719 - orf19.6972 1184578 1186719 1 1186719 1184578 1186367 1184715 SMI1B IPF7557.1|Contig4-2973_0016|orf6.7718|CA5019|SMI1|CaO19.6972|IPF7557 Protein of unknown function; transcription is negatively regulated by Rim101p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1186850 1191093 - orf19.6973 1186850 1191093 1 1191093 1186850 1190748 1186972 IPF7556.1|Contig4-2973_0015|orf6.7719|CA5020|LON1|CaO19.6973|IPF7556 Predicted ORF in Assemblies 19, 20 and 21; regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1191826 1192587 - ntar_628 1191826 1192587 1 1192587 1191826 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1192824 1194502 - orf19.6975 1192824 1194502 2 1194502|1193832 1194224|1192824 1194313 1193137 YST1 IPF7549.1|RPS0A|Contig4-2973_0009|orf6.7721|CA5022|orf19.6975.1|CA5021|YST1.exon2 Ribosome-associated protein; antigenic in mouse; complements S. cerevisiae yst1 yst2 mutant; similar to laminin-binding proteins, but does not bind laminin; possible S/T phosphorylation, N-glycosylation, myristoylation, Gcn4p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1194684 1195073 - ntar_629 1194684 1195073 1 1195073 1194684 1194887 1194759 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1195202 1197393 + orf19.6976 1195202 1197393 1 1195202 1197393 1195446 1197287 IPF7547.2|Contig4-2973_0006|orf6.7722|CA5023|CaO19.6976|IPF7547 Predicted membrane transporter; member of the proton coupled folate transporter/heme carrier protein (PCFT/HCP) family, major facilitator superfamily (MFS); virulence-group-correlated expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1197349 1199306 - orf19.6977 1197349 1199306 1 1199306 1197349 1199306 1197360 GPI1 IPF3009.2|orf6.7723|CA5024|CaO19.6977|IPF3009 Putative protein of GPI synthesis; expression is reduced in a fluconazole-resistant isolate [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1199266 1199694 - orf19.6978 1199266 1199694 1 1199694 1199266 1199595 1199266 IPF3008.1|Contig4-2646_0001|orf6.7724|CaO19.6978 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1201239 1204395 + orf19.6979 1201239 1204395 2 1201239|1201775 1201419|1204395 1201853 1204195 IPF3003.1|Contig4-2646_0008|Contig4-2646_0009|orf6.7725|CA5025|CaO19.6979|AMI3 Predicted ORF in Assemblies 19, 20 and 21; intron in 5'-UTR [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1204455 1204747 - ntar_630 1204455 1204747 1 1204747 1204455 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1204745 1205209 + ntar_631 1204745 1205209 1 1204745 1205209 1204745 1204879 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1205520 1207670 + orf19.6980 1205520 1207670 1 1205520 1207670 1205811 1207568 IPF3001.1|Contig4-2646_0012|orf6.7726|CA5026|CaO19.6980|IPF3001 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1207816 1209777 + orf19.6981 1207816 1209777 1 1207816 1209777 1207893 1209680 IPF2999.2|Contig4-2646_0013|orf6.7727|CA5027|CaO19.6981|IPF2999 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1209697 1211183 - orf19.6982 1209697 1211183 1 1211183 1209697 1211105 1209816 IPF2998.1|Contig4-2116_0001|Contig4-2646_0014|orf6.7728|CA5028|CaO19.6982|IPF2998 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1215423 1216013 + ntar_632 1215423 1216013 1 1215423 1216013 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1215930 1217629 - orf19.6983 1215930 1217629 1 1217629 1215930 1217362 1216190 IPF2997.1|Contig4-2787_0006|orf6.7729|CA5029|CaO19.6983|IPF2997 Predicted ORF in Assemblies 19, 20 and 21; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1222497 1222684 - ntar_633 1222497 1222684 1 1222684 1222497 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1226517 1229144 + orf19.6984 1226517 1229144 1 1226517 1229144 1226770 1229058 IPF2988.1|Contig4-2884_0009|Contig4-2884_0010|orf6.7730|CA5030|CaO19.6984|AVT42|IPF2988 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1229366 1232339 + orf19.6985 1229366 1232339 1 1229366 1232339 1229454 1232156 TEA1 IPF20023.1|Contig4-2884_0008|orf6.7731|CA5031|CaO19.6985|IPF20023 Putative transcription factor with zinc cluster DNA-binding motif; has similarity to S. cerevisiae Tea1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1232602 1232675 - tv(aac)5 1232602 1232675 1 1232675 1232602 tRNA-Val predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1232691 1232764 - tv(aac)6 1232691 1232764 1 1232764 1232691 tRNA-Val predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1233575 1233830 + snrnau6 1233575 1233830 1 1233575 1233830 SNR6 Highly conserved U6 small nuclear RNA involved in splicing; ortholog of S. cerevisiae SNR6; gene transcribed by RNA Pol III [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1233878 1236302 + orf19.6986 1233878 1236302 1 1233878 1236302 1234027 1236234 IPF2982.1|Contig4-2884_0003|Contig4-2884_0004|orf6.7732|CA5032|MSB3|CaO19.6986|IPF2982 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr3 1236260 1239217 - orf19.6987 1236260 1239217 1 1239217 1236260 1239021 1236421 DNM1 IPF2980.1|Contig4-2884_0002|orf6.7733|CA5033|CaO19.6987 Putative protein of unknown function; ; transcription is upregulated in an RHE model of oral candidiasis; transcription is regulated by Nrg1p, Mig1p, and Tup1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1239344 1239822 - ntar_634 1239344 1239822 1 1239822 1239344 1239469 1239344 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1240090 1241678 + orf19.6988 1240090 1241678 1 1240090 1241678 1240151 1241563 IPF4532.2|Contig4-2640_0001|Contig4-2640_0016|orf6.7734|CA5034|CaO19.6988|OST1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1241255 1241923 - orf19.6989 1241255 1241923 1 1241923 1241255 1241879 1241556 IPF4531.1|Contig4-2640_0002|orf6.7735|CA5035|CSP14|CaO19.6989|IPF4531 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1241941 1243037 - orf19.6990 1241941 1243037 1 1243037 1241941 1242796 1242005 IPF4530.1|Contig4-2640_0003|orf6.7736|CA5036|CaO19.6990|CPR52|CYP52 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1242028 1242443 + ntar_635 1242028 1242443 1 1242028 1242443 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1243169 1244182 + orf19.6991 1243169 1244182 1 1243169 1244182 1243216 1243860 PRE3 IPF4529.1|Contig4-2640_0005|orf6.7737|CA5037|CaO19.6991 Protein described as beta-1 subunit of proteasome; macrophage-induced protein; regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1244977 1246777 + orf19.6992 1244977 1246777 1 1244977 1246777 1245135 1246649 IPF4526.1|Contig4-2640_0010|orf6.7738|CA5038|CaO19.6992|QDR2 Predicted membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1246713 1248734 - orf19.6993 1246713 1248734 1 1248734 1246713 1248656 1246890 GAP2 orf6.7739|IPF4523.2|Contig4-2640_0013|CA5039|GAP13|CaO19.6993 Protein similar to amino acid permeases; ketoconazole, flucytosine repressed; induced by histidine, and induction requires Ssy1p; regulated by Nrg1p, Tup1p; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1250596 1251968 - orf19.6994 1250596 1251968 1 1251968 1250596 1251798 1250689 BAT22 IPF4517.1|Contig4-2640_0015|orf6.7740|CA5040|CaO19.6994|BAT1 Protein described as a branched chain amino acid aminotransferase; regulated by Gcn4p; induced in response to amino acid starvation (3-aminotriazole treatment), farnesol treatment [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1252889 1253952 + orf19.6995 1252889 1253952 1 1252889 1253952 1253107 1253952 IPF4516.1|Contig4-2915_0020|orf6.7741|CA5041|AFF4|CaO19.6995|FRP7 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chr3 1254552 1256914 + orf19.6996 1254552 1256914 1 1254552 1256914 1254651 1256708 IPF4514.1|Contig4-2915_0017|orf6.7742|CA5042|CaO19.6996|IPF4514 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1257418 1258260 + orf19.6997 1257418 1258260 1 1257418 1258260 1257418 1258260 IPF4513.1|Contig4-2915_0016|orf6.7743|CA5043|AFF5|CaO19.6997|FRP4 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1259057 1259910 + orf19.6998 1259057 1259910 1 1259057 1259910 1259057 1259860 GTT1 IPF4511.1|Contig4-2915_0014|orf6.7744|CA5044|GTT2|CaO19.6998|GTT14 Protein described as glutathione S-transferase; downregulated upon adherence to polystyrene; regulated upon white-opaque switching; induced in the presence of human neutrophils; oxidative stress-induced via Cap1p; regulated by Gcn2p, Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr3 1260331 1261608 + orf19.6999 1260331 1261608 1 1260331 1261608 1260331 1261608 IPF4510.1|Contig4-2915_0013|orf6.7745|CA5045|CaO19.6999|TCD5|IPF4510 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1262802 1263026 - ntar_636 1262802 1263026 1 1263026 1262802 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1263743 1265949 + orf19.7001 1263743 1265949 1 1263743 1265949 1263830 1265317 YCK2 IPF4506.1|Contig4-2915_0003|Contig4-2915_0005|orf6.7747|CA5046|CaO19.7001|YCK21 Plasma membrane protein similar to S. cerevisiae Yck2p, which is casein kinase I; null mutant has defect in damaging oral epithelial cells and in hyphal branching; transcription is activated in weak acid stress or on contact with host cells [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1266161 1267348 - orf19.7002 1266161 1267348 1 1267348 1266161 1267348 1266161 IPF4504.1|Contig4-2915_0001|orf6.7748|CA5047|CaO19.7002|IPF4504 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1268107 1269362 - ntar_637 1268107 1269362 1 1269362 1268107 1269188 1268847 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1268848 1270669 + orf19.7347 1268848 1270669 1 1268848 1270669 1269898 1270629 IPF7116.1|Contig4-2885_0019|orf6.8507|CA5648|CaO19.7347|UBC6 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1269579 1269899 - orf19.7348 1269579 1269899 1 1269899 1269579 1269899 1269579 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1273204 1273399 + ntar_638 1273204 1273399 1 1273204 1273399 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1273515 1273771 + ntar_639 1273515 1273771 1 1273515 1273771 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1274725 1277543 + orf19.7349 1274725 1277543 1 1274725 1277543 1275143 1277398 CHS4 SKT5|CSD4|CAL2|IPF7112.1|Contig4-2885_0008|Contig4-2885_0010|orf6.8509|CA5649|CaO19.7349 Activator of Chs3p chitin synthase; required for wild-type wall chitin content, but not for hyphal growth; mutant resistant to Calcofluor white; prenylation and 2 transmembrane segments predicted; functional homolog of S. cerevisiae Chs4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1278256 1278482 - ntar_640 1278256 1278482 1 1278482 1278256 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1279027 1279979 + orf19.7350 1279027 1279979 1 1279027 1279979 1279191 1279766 IPF7109.2|Contig4-2885_0005|orf6.8510|CA5650|CaO19.7350|IPF7109 Soluble protein in hyphae; fluconazole-induced; mRNA abundance is elevated in a cyr1 or ras1 null mutant and decreased mRNA abundance in an efg1 null mutant; regulated by Nrg1p, Tup1p, Tbf1p, Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1279864 1283062 - orf19.7353 1279864 1283062 1 1283062 1279864 1282919 1280001 IPF7105.2|Contig4-2885_0001|orf6.8513|CA5651|KIP3|CaO19.7353 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1283315 1285298 - orf19.7354 1283315 1285298 1 1285298 1283315 1284967 1283684 IPF19815.1|Contig4-2885_0022|orf6.8514|CA5652|CaO19.7354|LAC1|IPF19815 Predicted ORF in Assemblies 19, 20 and 21; caspofungin induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1285421 1285789 + ntar_641 1285421 1285789 1 1285421 1285789 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1285938 1287974 - orf19.7355 1285938 1287974 1 1287974 1285938 1287828 1286524 SSN8 IPF15544.1|Contig4-2029_0005|orf6.8515|CA5653|CaO19.7355 Protein not essential for viability; similar to S. cerevisiae Ssn8p, which is a component of RNA polymerase II holoenzyme [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1285978 1286562 + ntar_642 1285978 1286562 1 1285978 1286562 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1288222 1288554 - orf19.7356 1288222 1288554 1 1288554 1288222 1288554 1288222 IPF15543.2|Contig4-2029_0008|orf6.8516|CA5654|CaO19.7356|IPF15543 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1288388 1288630 + ntar_643 1288388 1288630 1 1288388 1288630 1288481 1288630 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1289412 1290836 + orf19.7357 1289412 1290836 1 1289412 1290836 1289709 1290755 orf6.8517|IPF18080.1|CA5655|CaO19.7357|IPF18080.3f|IPF18080 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1290739 1292419 - orf19.7358 1290739 1292419 1 1292419 1290739 1292374 1290851 IPF14683.2|Contig4-2195_0001|orf6.8518|CA5656|CaO19.7358|IPF14683 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1292665 1295619 - orf19.7359 1292665 1295619 1 1295619 1292665 1295015 1292820 CRZ1 IPF14682.2|Contig4-2195_0002|orf6.8519|CA5657|CaO19.7359|IPF14682 Putative transcription factor; similar to S. cerevisiae calcineurin-regulated transcription factor Crz1p; mutant is fluconazole hypersensitive; likely to act downstream of calcineurin; has C2H2 zinc fingers; not required for mouse virulence [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1296886 1298702 - orf19.7360 1296886 1298702 2 1298702|1298503 1298618|1296886 1298650 1298174 IPF1242.2|Contig4-2926_0026|orf6.8520|CA5658|CaO19.7360|IPF1242 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1298842 1300456 + orf19.7361 1298842 1300456 1 1298842 1300456 1298895 1300313 IPF1243.1|Contig4-2926_0024|orf6.8521|CA5659|SEN54|CaO19.7361 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1300278 1302788 - orf19.7362 1300278 1302788 1 1302788 1300278 1302588 1300375 SKN1 orf6.8522|IPF1245.1|SKN1.3|Contig4-2926_0022|Contig4-2926_0023|CA5660|SKN1.3f Protein with predicted role in beta-1,6-glucan synthesis; probable N-glycosylated type II membrane protein; transcription and change in mRNA length induced by yeast-hyphal transition; transcription induced by Rim101p or caspofungin [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr3 1304759 1305048 - ntar_644 1304759 1305048 1 1305048 1304759 1304890 1304759 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1305752 1308754 + orf19.7363 1305752 1308754 1 1305752 1308754 1306203 1308425 KRE6 IPF1249.2|Contig4-2926_0012|orf6.8523|CA5661|CaO19.7363 Protein of beta-1,6-glucan synthesis; essential; type II membrane protein; N-glycosylation sites; change in mRNA length, but not mRNA abundance, at yeast-hyphal transition; alkaline upregulated by Rim101p; induced on cell wall regeneration [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1309951 1311561 + orf19.7364 1309951 1311561 1 1309951 1311561 1309951 1311561 IPF1250.2|Contig4-2926_0007|orf6.8524|CA5662|CaO19.7364|IPF1250 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1312137 1314198 + orf19.7365 1312137 1314198 1 1312137 1314198 1312261 1313979 IPF1251.1|Contig4-2926_0004|orf6.8525|CA5663|FYV10|CaO19.7365|IPF1251 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr3 1313869 1315148 - orf19.7366 1313869 1315148 1 1315148 1313869 1315066 1314005 IPF1252.1|Contig4-2926_0003|orf6.8526|CA5664|CaO19.7366|IPF1252 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1315314 1318301 - orf19.7367 1315314 1318301 1 1318301 1315314 1317814 1315400 UBP1 IPF1255.1|Contig4-2926_0029|orf6.8527|CA5665|CaO19.7367 Protein described as ubiquitin carboxyl-1-terminal hydrolase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1318559 1320965 - orf19.7368 1318559 1320965 1 1320965 1318559 1320483 1318951 IPF1257.1|Contig4-3075_0021|orf6.8528|CA5666|CaO19.7368|PUB1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1321930 1323365 + orf19.7369 1321930 1323365 1 1321930 1323365 1321967 1323226 IPF1259.1|Contig4-3093_0001|orf6.8529|CA5667|CaO19.7369|IPF1259 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1322196 1322447 - ntar_645 1322196 1322447 1 1322447 1322196 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1322650 1323300 - ntar_646 1322650 1323300 1 1323300 1322650 1323190 1323044 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1323416 1325080 + orf19.7370 1323416 1325080 1 1323416 1325080 1323802 1324797 IPF1261.1|Contig4-3093_0003|orf6.8530|CA5668|CaO19.7370|IPF1261 Member of family of putative 7-transmembrane, PQ loop-family of G-protein-coupled receptors (GPCRs) similar to S. pombe Stm1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1325446 1328899 + orf19.7371 1325446 1328899 1 1325446 1328899 1325563 1328871 ZCF35|IPF1264.2|Contig4-3093_0006|orf6.8531|CA5669|CaO19.7371|IPF1264 Predicted zinc-cluster protein of unknown function [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr3 1329275 1332788 + orf19.7372 1329275 1332788 1 1329275 1332788 1329373 1332699 MRR1 HAP1|IPF1266.1|Contig4-3093_0008|orf6.8532|CA5670|ZCF36|CaO19.7372|IPF1266 Regulator of MDR1 transcription; zinc-finger protein; gain-of-function mutations cause upregulation of MDR1 (which encodes plasma membrane multidrug efflux pump) and consequent multidrug resistance [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1333322 1333620 + ntar_647 1333322 1333620 1 1333322 1333620 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1333343 1333486 - ntar_648 1333343 1333486 1 1333486 1333343 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1333794 1337059 + orf19.7374 1333794 1337059 1 1333794 1337059 1333935 1336985 CTA4 IPF1269.1|Contig4-3093_0011|orf6.8534|CA5671|CaO19.7374 Predicted transcription factor involved in response to nitric oxide; downregulated upon adherence to polystyrene; induced by nitric oxide; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1336903 1337766 - orf19.7375 1336903 1337766 1 1337766 1336903 1337713 1337099 IPF1271.1|Contig4-3093_0012|orf6.8535|CA5672|CaO19.7375|USA1|IPF1271|U1A Putative U1A component of the U1 snRNP, involved in splicing; contains two RNA recognition motifs (RRMs); ortholog of S. cerevisiae MUD1; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1337855 1340239 + orf19.7376 1337855 1340239 1 1337855 1340239 1337896 1340184 IPF1272.1|Contig4-3093_0013|orf6.8536|CA5673|CaO19.7376|IPF1272 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1340411 1343396 + orf19.7377 1340411 1343396 1 1340411 1343396 1340552 1343272 ASE1 IPF1274.2|Contig4-3093_0015|Contig4-3093_0018|orf6.8537|CA5674|CaO19.7377|IPF1274 Predicted ORF in Assemblies 19, 20 and 21; member of conserved Mcm1p regulon; periodic mRNA expression, peak at cell-cycle G2/M phase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1343311 1345211 - orf19.7378 1343311 1345211 1 1345211 1343311 1345058 1343442 IPF1276.1|Contig4-3093_0019|orf6.8538|CA5675|SIS2|CaO19.7378 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1345340 1345775 + ntar_649 1345340 1345775 1 1345340 1345775 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1345681 1348438 - orf19.7379 1345681 1348438 1 1348438 1345681 1347977 1345713 FAA2 IPF1278.1|FAA2-4|Contig4-3093_0023|orf6.8539|CA5676|FAA22|CaO19.7379|FAA24 Predicted acyl CoA synthetase; expression is regulated upon white-opaque switching [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr3 1348635 1348933 + ntar_650 1348635 1348933 1 1348635 1348933 1348796 1348933 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1349459 1352501 - orf19.7380 1349459 1352501 2 1352501|1349654 1350366|1349459 1352464 1349459 IPF1286.1|Contig4-3093_0029|orf6.8540|CA5677|IPF1286 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGD orf_changed=false scenario_first_exon=G scenario_last_exon=Z] Ca21chr3 1361399 1365069 + orf19.7381 1361399 1365069 1 1361399 1365069 1362622 1364496 ZCF37|IPF1292|IPF1292.1|Contig4-3093_0048|orf6.8541|CA5678|CaO19.7381 Predicted zinc-finger protein of unknown function; not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1366696 1368356 + orf19.7382 1366696 1368356 2 1366696|1367162 1366932|1368356 1366734 1368201 CAM1 IPF1299.1|IPF1296.1|Contig4-3093_0051|orf6.8542|orf19.7381.3|CA5679|CA5680|CAM1.exon2 Putative translation elongation factor eEF1 gamma; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1368557 1370023 + orf19.7383 1368557 1370023 1 1368557 1370023 1368783 1369889 MNN9 IPF1301.1|Contig4-3093_0053|Contig4-3093_0054|orf6.8543|CA5681|CaO19.7383 Protein of N-linked outer-chain mannan biosynthesis; mutant has defective cell wall; required for wild-type hyphal growth; mutant is hygromycin B sensitive and vanadate resistant; has N-terminal membrane-spanning segment (positions 18-34) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1370239 1372358 + orf19.7384 1370239 1372358 1 1370239 1372358 1370296 1372218 NOG1 IPF1302.2|Contig4-3036_0030|orf6.8544|CA5682|CaO19.7384 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1373823 1375328 + orf19.7385 1373823 1375328 1 1373823 1375328 1373823 1375328 IPF3333.1|Contig4-3036_0025|orf6.8545|CA5683|CaO19.7385|LEE1|IPF3333 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1375362 1376425 - orf19.7386 1375362 1376425 1 1376425 1375362 1376389 1375514 IPF3331.1|Contig4-3036_0022|orf6.8546|CA5684|MBA1|CaO19.7386|IPF3331 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1376578 1378432 + orf19.7387 1376578 1378432 1 1376578 1378432 1376658 1378301 ELP3 IPF3330.1|Contig4-3036_0021|orf6.8547|CA5685|CaO19.7387|HPA1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1378328 1380197 - orf19.7388 1378328 1380197 1 1380197 1378328 1380061 1378424 PBS2 IPF3329.1|Contig4-3036_0020|orf6.8548|CA5686|CaO19.7388|IPF3329 MAPK kinase (MAPKK); role in osmotic and oxidative stress responses, oxidative stress adaptation; required for stress regulation of Hog1p localization and activity; functional homolog of S. cerevisiae Pbs2p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1380632 1385792 + orf19.7389 1380632 1385792 1 1380632 1385792 1380648 1385540 REV3 IPF3327.2|Contig4-3036_0014|Contig4-3036_0018|orf6.8549|orf6.8550|REV3.5F|CA5687|CA5689|orf19.7390 Protein not essential for viability; similar to S. cerevisiae Rev3p, which is a subunit of DNA polymerase zeta [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr3 1385563 1386875 - orf19.7391 1385563 1386875 1 1386875 1385563 1386774 1385617 OCH1 IPF3324.1|Contig4-3036_0012|orf6.8551|CA5690|CaO19.7391 alpha-1,6-mannosyltransferase; initiates N-glycan outer chain branch addition; similar to S. cerevisiae Och1p; required for wild-type virulence in mouse intravenous infection; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1387099 1390042 - orf19.7392 1387099 1390042 1 1390042 1387099 1390002 1387984 IPF3320.1|Contig4-3036_0007|orf6.8552|CA5691|DED1|CaO19.7392 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1390538 1390781 + ntar_651 1390538 1390781 1 1390538 1390781 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1390776 1393336 - orf19.7393 1390776 1393336 1 1393336 1390776 1392925 1391147 IPF3316.1|Contig4-3036_0004|Contig4-3036_0005|orf6.8553|CA5692|CaO19.7393|UTR1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1393397 1393694 + ntar_652 1393397 1393694 1 1393397 1393694 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1393732 1395860 - orf19.7394 1393732 1395860 1 1395860 1393732 1395623 1393824 GDA1 IPF3313.1|Contig4-3036_0003|orf6.8554|CA5693|CaO19.7394 Golgi membrane GDPase, required for wild-type O-mannosylation, not N-glycosylation; required for wild-type hyphal induction, cell wall, and cell surface charge; not required for HeLa cell adherence; functional homolog of S. cerevisiae Gda1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1395707 1396024 + orf19.7395 1395707 1396024 1 1395707 1396024 1395707 1396024 IPF27313.1|orf6.8555|CaO19.7395 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1397112 1398317 + orf19.7396 1397112 1398317 1 1397112 1398317 1397112 1398317 IPF3311.2|Contig4-2982_0013|orf6.8556|CA5694|CaO19.7396|IPF3311 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr3 1399071 1402480 + orf19.7397 1399071 1402480 1 1399071 1402480 1399184 1402453 IPF3310.1|Contig4-2982_0012|orf6.8557|CA5695|CaO19.7397|IPF3310 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1403603 1404393 + ntar_653 1403603 1404393 1 1403603 1404393 1403603 1404265 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1406044 1406634 - orf19.7417 1406044 1406634 1 1406634 1406044 1406634 1406044 TSA1 orf6.8577|IPF2431.1|TSA1A|Contig4-2982_0001|CA5714|CaO19.7417|IPF2431|CA5697|IPF18076.3f|IPF18076.1 Protein of TSA/alkyl hydroperoxide peroxidase C (AhPC) family; similar to thiol-dependent peroxidases of oxidative stress signaling; antigenic; hyphal surface, nucleus; yeast-form nucleus, cytoplasm; biofilm, phagocytosis, peroxide induced [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1407371 1407515 + ntar_654 1407371 1407515 1 1407371 1407515 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1407874 1411974 - orf19.7414 1407874 1411974 1 1411974 1407874 1411974 1407874 ALS6 ALS97|IPF2663.2|Contig4-2957_0018|orf6.2110|CA5713|CaO19.7414|orf6.8574 [NOT TRANSCRIBED?] ALS family protein; expression in S. cerevisiae confers adhesion to gelatin; macrophage-induced gene; N-terminal adhesion domain; ALS family includes cell-surface glycoproteins, some with adhesin function [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr3 1415835 1416997 - orf19.7413 1415835 1416997 1 1416997 1415835 1416937 1416119 MMS21 IPF2657.1|Contig4-2957_0012|orf6.8573|CA5712|CaO19.7413|IPF2657 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1417162 1419622 - orf19.7412 1417162 1419622 1 1419622 1417162 1419479 1417278 MUB1 IPF2656.1|Contig4-2957_0011|orf6.8572|CA5711|CaO19.7412 Protein not essential for viability; similar to S. cerevisiae Mub1p, which has a role in regulation of budding [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1419866 1421049 - orf19.7411 1419866 1421049 1 1421049 1419866 1420990 1419938 OAC1 IPF2654.1|Contig4-2957_0008|orf6.8571|CA5710|CaO19.7411 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1421460 1424753 + orf19.7410 1421460 1424753 1 1421460 1424753 1421548 1424652 IPF2653|IPF2653.1|Contig4-2957_0004|orf6.8570|CA5709|CaO19.7410 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1424576 1425124 - orf19.7409.1 1424576 1425124 1 1425124 1424576 1424953 1424741 IPF2652.2|CA5708|MRPL39 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1425296 1426543 + orf19.7409 1425296 1426543 1 1425296 1426543 1425327 1425974 ERV25 IPF2651.2|Contig4-3029_0001|orf6.8569|CA5707|CaO19.7409 Transcription is induced upon filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1425835 1428058 - orf19.7406 1425835 1428058 1 1428058 1425835 1428031 1425971 IPF2649.1|Contig4-3029_0002|orf6.8566|CA5706|SEC20|CaO19.7406|IPF2649 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1428196 1429423 - orf19.7405 1428196 1429423 1 1429423 1428196 1429275 1428571 IPF2645.2|Contig4-3029_0003|orf6.8565|CA5705|CaO19.7405|IPF2645 Predicted ORF in Assemblies 19, 20 and 21; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1429643 1430805 + orf19.7404 1429643 1430805 1 1429643 1430805 1429707 1430705 IPF2644.2|Contig4-3029_0004|orf6.8564|CA5704|CaO19.7404|CHA1|CHA11 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1431186 1433755 + orf19.7403 1431186 1433755 1 1431186 1433755 1431434 1433689 IPF2643.1|Contig4-3029_0008|orf6.8563|CA5703|CaO19.7403|IPF2463 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1433123 1433731 - ntar_655 1433123 1433731 1 1433731 1433123 1433731 1433504 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1434002 1438461 + orf19.7402 1434002 1438461 1 1434002 1438461 1434294 1438325 DOT1 IPF2639.1|Contig4-3029_0012|orf6.8562|CA5702|CaO19.7402|PCH1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1438410 1441874 - orf19.7401 1438410 1441874 1 1441874 1438410 1441681 1438511 ISW2 IPF2633.1|Contig4-3029_0013|CA5701|CaO19.7401|orf6.8561 Protein required for chlamydospore formation, not essential for viability; repressed upon high-level peroxide stress; similar to S. cerevisiae Isw2p, which is an ATPase involved in chromatin remodeling [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1442408 1442638 + ntar_656 1442408 1442638 1 1442408 1442638 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1446613 1451319 + orf19.7400 1446613 1451319 1 1446613 1451319 1446613 1451319 ALS7 ALS94|ALS95|ALS96|ALS98|IPF19816.1|Contig4-2957_0018|CA5699|CaO19.7400|orf6.8560 ALS family protein; hypermutable contingency gene; growth-regulated, downregulated in biofilm; two variable repeat regions; expression in S. cerevisiae does not confer adhesiveness; ALS family includes adhesins, cell-surface glycoproteins [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr3 1451375 1451836 - ntar_657 1451375 1451836 1 1451836 1451375 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1452473 1453063 + orf19.7398.1 1452473 1453063 1 1452473 1453063 1452473 1453063 TSA1B IPF18075.2|TSA1|CA5698|IPF10875.5f Putative peroxidase; orf19.7398.1 is contig-truncated fragment of gene identical to TSA1; Tsa1p and Tsa1Bp role under oxidative/reductive stress, hyphal cell wall formation; in hyphal nucleus, cell wall; yeast-form nucleus, cytoplasm [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1453315 1453913 + orf19.7419 1453315 1453913 1 1453315 1453913 1453315 1453857 HNT2 IPF2434.1|Contig4-2982_0003|orf6.8579|CA5715|CaO19.7419 Predicted ORF in Assemblies 19, 20 and 21; induced upon low-level peroxide stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr3 1453976 1454767 + orf19.7420 1453976 1454767 1 1453976 1454767 1453976 1454767 IPF2436.1|Contig4-2982_0004|orf6.8580|CA5716|CaO19.7420|MED6 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1454844 1455511 - orf19.7421 1454844 1455511 1 1455511 1454844 1455479 1454868 CYP5 CYP51|IPF2438.1|Contig4-2982_0006|orf6.8581|CA5717|CaO19.7421|CPR51 Protein described as a peptidyl-prolyl cis-trans isomerase; macrophage-downregulated protein level; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1455527 1456911 - orf19.7422 1455527 1456911 1 1456911 1455527 1456911 1455739 IPF2440.1|Contig4-2982_0008|orf6.8582|CA5718|LCP5|CaO19.7422 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1457024 1457809 + orf19.7424 1457024 1457809 1 1457024 1457809 1457024 1457809 NSA2 IPF2441.1|Contig4-2982_0009|Contig4-3080_0023|orf6.8584|CA5719|CaO19.7424|IPF2441 Predicted ORF in Assemblies 19, 20 and 21; decreased expression in response to prostaglandins [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1457312 1457809 + orf19.7398 1457312 1457809 1 1457312 1457809 1457420 1457809 IPF3309.1|orf6.8558|CA5696|IPF3309.3eoc Predicted ORF in Assemblies 19, 20 and 21; decreased expression in response to prostaglandins [label_first_exon=CGD label_last_exon=CGD orf_changed=true scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1457891 1459253 - orf19.7425 1457891 1459253 1 1459253 1457891 1459194 1458034 IPF2442.1|Contig4-3080_0022|orf6.8585|CA5720|CaO19.7425|UNG1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1459423 1460581 - orf19.7426 1459423 1460581 1 1460581 1459423 1460546 1459524 IPF2443.1|Contig4-3080_0021|orf6.8586|CA5721|OST6|CaO19.7426|IPF2443 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1460667 1462120 - orf19.7427 1460667 1462120 1 1462120 1460667 1461976 1460762 IPF2446.1|Contig4-3080_0020|orf6.8587|CA5722|CaO19.7427|IPF2446 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1462346 1463627 + orf19.7428 1462346 1463627 2 1462346|1462500 1462409|1463627 1462396 1463580 APN1 IPF2448.1|Contig4-3080_0019|orf6.8588|CA5723|CaO19.7428 Ortholog of S. cerevisiae Apn1p, which is an AP endonuclease; transcriptionally induced by interaction with macrophage; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1463644 1467148 + orf19.7433 1463644 1467148 1 1463644 1467148 1463644 1466934 IPF19817.1|Contig4-3080_0015|Contig4-3080_0017|Contig4-3080_0018|orf6.8593|CA5724|NUP116|CaO19.7433 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1467942 1469438 + orf19.7434 1467942 1469438 1 1467942 1469438 1468019 1469104 GLG2 IPF2460.2|Contig4-3080_0014|orf6.8594|CA5725|CaO19.7434|GLG22 Protein described as self-glucosylating initiator of glycogen synthesis; expression is regulated upon white-opaque switching; hyphal-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1469417 1469715 - th(gug)3 1469417 1469715 2 1469715|1469652 1469679|1469417 tRNA-His predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1476322 1476526 + ntar_658 1476322 1476526 1 1476322 1476526 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1476674 1476840 + ntar_659 1476674 1476840 1 1476674 1476840 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1477000 1479222 + orf19.7436 1477000 1479222 1 1477000 1479222 1477308 1479146 AAF1 CAD1|IPF2468.1|Contig4-3080_0008|Contig4-3080_0010|orf6.8596|CA5726|CaO19.7436 Possible regulatory protein; Glu-rich domain; production in S. cerevisiae increases endothelial cell adherence and flocculence; expressed under diverse conditions, detected in yeast-form and hyphal cells; alkaline or caspofungin upregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1479064 1479862 - orf19.7436.1 1479064 1479862 2 1479862|1479610 1479745|1479064 1479789 1479317 ECM15 IPF2469.1|CA5727 ORF Predicted by Annotation Working Group; caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1480085 1480524 - ntar_660 1480085 1480524 1 1480524 1480085 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1481998 1482965 + orf19.7437 1481998 1482965 1 1481998 1482965 1481998 1482921 IPF2471.1|Contig4-3080_0004|orf6.8597|CA5728|CaO19.7437|MAA1|IPF2471 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1482528 1482919 - ntar_661 1482528 1482919 1 1482919 1482528 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1483085 1486321 + orf19.7438 1483085 1486321 1 1483085 1486321 1483162 1486227 UBA1 IPF2475.1|Contig4-3080_0002|orf6.8598|CA5729|CaO19.7438 Protein similar to S. cerevisiae Uba1p, which is a ubiquitin-activating enzyme that is essential for growth; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1486352 1490323 - orf19.7440 1486352 1490323 1 1490323 1486352 1490323 1486352 HST6 STE6|IPF2479.2|Contig4-2076_0006|orf6.8600|CA5730|CaO19.7440 Functional homolog of S. cerevisiae Ste6p (a-pheromone transporter); required for mating of MTLa cells; ABC transporter related to mammalian P-glycoproteins; a-type specific, not regulated during white-opaque or yeast-hyphal switching [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1490460 1491993 - orf19.7441 1490460 1491993 1 1491993 1490460 1491920 1490994 IPF2870.2|Contig4-2076_0005|orf6.8601|CA5731|CaO19.7441|IPF2870 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1492068 1493146 + orf19.7442 1492068 1493146 1 1492068 1493146 1492168 1493064 IPF2872.2|Contig4-2076_0002|orf6.8602|CA5732|CaO19.7442|IPF2872 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1492420 1493870 - orf19.7443 1492420 1493870 1 1493870 1492420 1493870 1493103 IPF2873.1|Contig4-2076_0001|orf6.8603|CA5733|CaO19.7443|IPF2873 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1493879 1495015 - orf19.7444 1493879 1495015 1 1495015 1493879 1494904 1493879 IPF20029.1|orf6.8604|CA5734|CaO19.7444|IPF20029 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1496187 1498244 + orf19.7445 1496187 1498244 1 1496187 1498244 1496411 1497898 IPF2878.1|Contig4-2403_0005|orf6.8605|CA5735|VID24|CaO19.7445|IPF2878 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1498222 1499249 - orf19.7446 1498222 1499249 1 1499249 1498222 1499183 1498506 OPI3 IPF2880.1|Contig4-2403_0004|orf6.8606|CA5736|CaO19.7446 Putative phosphatidylethanolamine N-methyltransferase of phosphatidylcholine biosynthesis; downregulation correlates with clinical development of fluconazole resistance; amphotericin B repressed; caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1502028 1503653 + orf19.7447 1502028 1503653 1 1502028 1503653 1502028 1503653 JEN1 IPF2882.1|Contig4-3064_0026|orf6.8607|CA5737|CaO19.7447 Lactate transporter; transcriptionally induced by lactic acid, activated by Cat8p; alkaline downregulated by Rim101p; localizes to plasma membrane; similar to S. cerevisiae Jen1p [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1504090 1505503 + orf19.7448 1504090 1505503 1 1504090 1505503 1504116 1505450 LYS9 IPF2883.1|Contig4-3064_0025|orf6.8608|CA5738|CaO19.7448 Putative enzyme of lysine biosynthesis; soluble protein in hyphae; amphotericin B repressed; Gcn4p-regulated; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1505418 1507317 - orf19.7449 1505418 1507317 1 1507317 1505418 1507230 1505509 IPF2884.1|Contig4-3064_0024|orf6.8609|CA5739|CaO19.7449|IPF2884 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1508125 1509473 + orf19.7450 1508125 1509473 1 1508125 1509473 1508297 1509388 IPF20030.1|Contig4-3064_0020|Contig4-3064_0021|orf6.8610|CA5740|BNI5|CaO19.7450|IPF20030 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1510954 1515181 + orf19.7451 1510954 1515181 1 1510954 1515181 1511034 1515005 FUN31 IPF2894.1|Contig4-2597_0004|Contig4-3064_0016|orf6.8611|orf6.974|CA5742|PSK1|CaO19.7451|PSK2 Putative PAS kinase involved in cell wall damage response; similar to S. cerevisiae Psk1p, which is a putative serine/threonine protein kinase; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1515378 1517650 + orf19.7452 1515378 1517650 1 1515378 1517650 1515440 1517650 IPF2895.2|Contig4-3064_0013|Contig4-3064_0014|orf6.8612|CA5743|CaO19.7452|IPF2895 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1517651 1518699 + orf19.7453 1517651 1518699 1 1517651 1518699 1517876 1518697 IPF2898.2|Contig4-3064_0011|Contig4-3064_0012|orf6.8613|CA5744|CaO19.7453|IPF2898 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1518712 1520430 - orf19.7454 1518712 1520430 1 1520430 1518712 1520340 1518781 TAF60 IPF2900.1|Contig4-3064_0010|orf6.8614|CA5745|CaO19.7454|TAF6 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to amphotericin B [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1520538 1521617 - orf19.7455 1520538 1521617 1 1521617 1520538 1521617 1520538 IPF2902.1|Contig4-3064_0009|orf6.8615|CA5746|CaO19.7455|IPF2902 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1523505 1524897 - orf19.7456 1523505 1524897 1 1524897 1523505 1524694 1523630 IPF2903.1|Contig4-3064_0008|orf6.8616|CA5747|CaO19.7456|IPF2903 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1525184 1526274 - orf19.7457 1525184 1526274 1 1526274 1525184 1526236 1525352 IPF2905.1|Contig4-3064_0006|orf6.8617|CA5748|CaO19.7457|IPF2905 Predicted ORF in Assemblies 19, 20 and 21; shows Mob2p-dependent hyphal regulation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1526334 1527173 - orf19.7458 1526334 1527173 1 1527173 1526334 1527005 1526640 IPF2906.1|orf6.8618|SKO1|CaO19.7458 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1527333 1529825 - orf19.7459 1527333 1529825 1 1529825 1527333 1529427 1527586 IPF2908.1|Contig4-3064_0002|orf6.8619|CA5749|CaO19.7459|IPF2908 Predicted ORF in Assemblies 19, 20 and 21; fluconazole-induced; ketoconazole-repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1531005 1535241 + orf19.6832 1531005 1535241 1 1531005 1535241 1531143 1533269 orf19.14124|orf19.14125|IPF20332.1|IPF12080.1|IPF20329.1|IPF12082.2|Contig4-2530_0001|Contig4-2530_0005|Contig4-2530_0007|Contig4-2530_0013|orf6.8799|orf6.8798|CA5877|CA5876|orf19.6833|CaO19.6832|CaO19.14124|IPF12082.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1535409 1538341 + orf19.6831 1535409 1538341 1 1535409 1538341 1535436 1538090 PRP5 orf19.14123|IPF20305.1|IPF12079.1|Contig4-2530_0008|orf6.8800|CA5878|CaO19.14123|CaO19.6831 Protein described as a pre-mRNA processing RNA-helicase; induced upon adherence to polystyrene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1538328 1539131 - ntar_662 1538328 1539131 1 1539131 1538328 1538806 1538681 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1538367 1539279 + orf19.6830 1538367 1539279 1 1538367 1539279 1538409 1539206 orf19.14122|IPF20403.1|IPF12076.1|Contig4-2530_0009|orf6.8801|CA5879|CaO19.14122|CaO19.6830|IPF12076 Putative enoyl-CoA hydratase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1539435 1541461 + orf19.6829 1539435 1541461 1 1539435 1541461 1539478 1541442 orf19.14121|IPF20334.1|IPF12074.2|Contig4-2530_0011|orf6.8802|CA5880|AEP2|CaO19.14121|CaO19.6829|IPF12074 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1541642 1542378 + orf19.6828.1 1541642 1542378 1 1541642 1542378 1541743 1541949 IPF20322.1|IPF2429.2|CA5881|SSS1 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1542467 1543583 + orf19.6828 1542467 1543583 1 1542467 1543583 1542612 1543439 orf19.14120|IPF20399.1|IPF20032.1|Contig4-2033_0003|orf6.8803|CA5882|RRP1|CaO19.6828|CaO19.14120 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1543757 1546322 + orf19.6827 1543757 1546322 1 1543757 1546322 1543880 1544932 SLU7 orf19.14119|IPF20380.1|IPF2425.1|Contig4-2033_0005|Contig4-2033_0006|orf6.8804|CA5883|CaO19.14119|CaO19.6827|IPF2425 Protein similar to S. cerevisiae Slu7p; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1544953 1546146 - orf19.6826 1544953 1546146 1 1546146 1544953 1546146 1544953 SLF1 orf19.14118|IPF20376.1|IPF2424.1|Contig4-2033_0007|orf6.8805|CA5884|CaO19.6826|CaO19.14118 Predicted ORF in Assemblies 19, 20 and 21; transcription is induced in response to alpha pheromone in SpiderM medium; macrophage-induced gene [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1549100 1550503 + orf19.6824 1549100 1550503 1 1549100 1550503 1549100 1550503 orf19.14116|IPF20362.1|IPF2419.1|Contig4-2745_0006|orf6.8807|CA5885|CaO19.6824|CaO19.14116|IPF2419 Predicted ORF in Assemblies 19, 20 and 21; appears to be C. albicans-specific; induced upon biofilm formation; transcription is repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1550585 1552065 - orf19.6822 1550585 1552065 2 1552065|1551694 1551881|1550585 1551883 1550807 orf19.14114|IPF20390.1|IPF2417.1|Contig4-2745_0005|orf6.8809|CA5886|CaO19.6822|CaO19.14114|IPF2417 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1552206 1554879 + orf19.6821 1552206 1554879 1 1552206 1554879 1552318 1554741 orf19.14113|IPF20313.1|IPF2415.1|Contig4-2745_0004|orf6.8810|CA5887|APC2|CaO19.14113|CaO19.6821|IPF2415 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1554471 1556375 - orf19.6820 1554471 1556375 1 1556375 1554471 1556335 1554788 orf19.14112|IPF20360.1|IPF2414.1|Contig4-2745_0002|orf6.8811|CA5888|CaO19.14112|CaO19.6820|IPF2414 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1556536 1560714 - orf19.6818 1556536 1560714 1 1560714 1556536 1560675 1556563 orf19.14110|IPF20440.1|IPF2409.2|Contig4-2745_0001|orf6.8813|CA5889|CaO19.14110|CaO19.6818|IPF2409 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1560751 1561053 - tw(cca)2 1560751 1561053 2 1561053|1560993 1561017|1560751 tW(CCA)2.2 tRNA-Trp predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGDmod orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1567804 1570471 + orf19.6817 1567804 1570471 1 1567804 1570471 1568561 1570114 FCR1 orf19.14109|IPF20357.1|IPF2404.1|Contig4-3076_0005|orf6.8814|CA5890|CaO19.14109|CaO19.6817 Putative zinc cluster transcription factor; negative regulator of fluconazole, ketoconazole, brefeldin A resistance; transposon mutation affects filamentous growth; partially suppresses S. cerevisiae pdr1 pdr3 mutant fluconazole sensitivity [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1567889 1568204 - ntar_663 1567889 1568204 1 1568204 1567889 1568204 1568061 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1572496 1573886 - orf19.6816 1572496 1573886 1 1573886 1572496 1573420 1572572 orf19.14108|IPF20400.1|IPF2400.1|Contig4-3076_0009|orf6.8815|CA5891|CaO19.6816|CaO19.14108|IPF2400 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1574318 1574547 + ntar_664 1574318 1574547 1 1574318 1574547 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1574904 1576161 + orf19.6814 1574904 1576161 1 1574904 1576161 1574975 1575982 TDH3 orf19.14106|TDH1|GAP|GAP1|G3P|IPF20384.1|IPF2397.2|Contig4-3076_0010|orf6.8817|CA5892|CaO19.14106|CaO19.6814 Glyceraldehyde-3-phosphate dehydrogenase; enzyme of glycolysis; binds fibronectin and laminin; at surface of yeast-form cells and hyphae; soluble in hyphae; antigenic during infection; NAD-linked; farnesol-downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1576247 1577066 + orf19.6813 1576247 1577066 1 1576247 1577066 1576263 1577066 orf19.14105|IPF20397.1|IPF2392.2|Contig4-3076_0011|orf6.8818|CA5893|CaO19.14105|CaO19.6813|IPF2392 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1577290 1579916 + orf19.6812 1577290 1579916 1 1577290 1579916 1577400 1579709 PMT2 orf19.14104|IPF20316.1|IPF2391.2|Contig4-3076_0013|orf6.8819|CA5894|CaO19.6812|CaO19.14104 Essential protein mannosyltransferase with roles in hyphal growth and drug sensitivity; member of the PMT family which includes Pmt1p, Pmt2p, Pmt4p, Pmt5p, and Pmt6p; induced during cell wall regeneration [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1580078 1580953 + orf19.6811 1580078 1580953 1 1580078 1580953 1580118 1580816 orf19.14103|IPF20411.1|IPF2389.2|Contig4-3076_0015|orf6.8820|CA5895|CaO19.6811|ISA2|CaO19.14103 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1580712 1583145 - orf19.6810 1580712 1583145 1 1583145 1580712 1582863 1580932 orf19.14102|IPF20335.1|IPF2388.1|Contig4-3076_0016|orf6.8821|CA5896|CaO19.6810|TPD3|CaO19.14102 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1583972 1585270 + orf19.6809 1583972 1585270 1 1583972 1585270 1584185 1585153 orf19.14101|IPF20381.1|IPF2384.1|Contig4-3076_0019|orf6.8822|CA5897|CaO19.14101|PMU1|CaO19.6809|IPF2384 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1585170 1585396 - ntar_665 1585170 1585396 1 1585396 1585170 1585396 1585262 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1585386 1587215 + orf19.6807 1585386 1587215 1 1585386 1587215 1585386 1587215 orf19.14099|IPF20336.1|IPF2382.1|Contig4-3076_0021|orf6.8824|CA5899|CaO19.6807|CaO19.14099|IPF2382 Predicted ORF in retrotransposon Tca17 with similarity to parts of the Gag-Pol region of retrotransposons; clade-associated gene expression [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1587027 1587491 - ntar_666 1587027 1587491 1 1587491 1587027 1587341 1587027 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1589728 1590266 + ntar_667 1589728 1590266 1 1589728 1590266 1589885 1590148 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1591351 1595115 + orf19.6805 1591351 1595115 1 1591351 1595115 1592069 1594900 orf19.14097|IPF20302.1|IPF2374.2|orf6.8826|CA5901|CaO19.14097|CaO19.6805|IPF2374 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1595029 1595303 - ty(gua)3 1595029 1595303 2 1595303|1595223 1595267|1595029 tY(GUA)3.2 tRNA-Tyr predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGDmod orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1595878 1597804 + orf19.6804 1595878 1597804 1 1595878 1597804 1595940 1597760 orf19.14096|IPF20333.1|IPF5941.2|Contig4-2895_0002|orf6.8827|CA5902|CaO19.14096|SRP68|CaO19.6804 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1597952 1599260 + orf19.6803 1597952 1599260 1 1597952 1599260 1598019 1599131 HUT1 orf19.14095|IPF20379.1|IPF5942.1|Contig4-2120_0003|orf6.8828|CA5903|CaO19.14095|CaO19.6803|IPF5942 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1599445 1600716 + orf19.6802 1599445 1600716 1 1599445 1600716 1599489 1600649 orf19.14094|IPF20378.1|IPF5944.1|Contig4-2120_0002|orf6.8829|CA5904|CaO19.14094|CaO19.6802|IPF5944 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1600886 1602700 + orf19.6801 1600886 1602700 1 1600886 1602700 1600945 1602678 RPD31 orf19.14093|IPF20341.1|IPF5946.2|orf6.8830|CA5905|RPD32|CaO19.14093|CaO19.6801 Putative ortholog histone deacetylase; involved in regulation of white-opaque switching; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1603100 1604852 + orf19.6800 1603100 1604852 1 1603100 1604852 1603170 1604738 POS5 orf19.14092|IPF20354.1|IPF5949.2|orf6.8831|CA5906|CaO19.14092|CaO19.6800|IPF5949 Protein likely to be essential for growth, based on an insertional mutagenesis strategy; similar to S. cerevisiae Pos5p, which is a mitochondrial NADH kinase involved in the oxidative stress response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1607528 1611501 + orf19.6798 1607528 1611501 1 1607528 1611501 1608042 1611284 SSN6 orf19.14090|IPF20461.1|IPF5957.1|Contig4-2796_0009|orf6.8833|CA5907|CaO19.14090|CYC8|CaO19.6798 Functional homolog of S. cerevisiae Cyc8p/Ssn6p; Ssn6p and Tup1p regulate distinct sets of genes; hyphal growth regulator; overexpression or mutation causes avirulence in mouse IV infection; TPR motifs; repressed during hyphal growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1611510 1614202 - orf19.6797 1611510 1614202 1 1614202 1611510 1614158 1611630 orf19.14089|IPF20311.1|IPF5960.1|Contig4-2796_0008|orf6.8834|CA5908|CaO19.14089|CaO19.6797|IPF5960 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr3 1614442 1615259 - orf19.6796 1614442 1615259 1 1615259 1614442 1615205 1614504 orf19.14088|IPF20413.1|IPF5962.1|Contig4-2796_0005|orf6.8835|CA5909|CaO19.6796|YSA1|CaO19.14088 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1615243 1616192 + orf19.6795 1615243 1616192 1 1615243 1616192 1615530 1615889 orf19.14087|IPF20449.1|IPF5964.1|Contig4-2796_0002|orf6.8836|CA5910|CaO19.6795|CaO19.14087|IPF5964 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1616370 1617609 + orf19.6794 1616370 1617609 1 1616370 1617609 1616648 1617319 FESUR1 orf19.14086|IPF20407.1|IPF5965.1|Contig4-2796_0001|orf6.8837|CA5911|CaO19.6794|CaO19.14086|IPF5965 Protein described as ubiquinone reductase; transcriptionally induced by interaction with macrophage; alkaline downregulated; repressed by nitric oxide; clade-associated gene expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1617669 1618766 - orf19.6793 1617669 1618766 1 1618766 1617669 1618766 1617669 orf19.14085|IPF20374.1|IPF5966.2|orf6.8838|CA5912|CaO19.6793|CaO19.14085|IPF5966 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr3 1617720 1618090 + ntar_668 1617720 1618090 1 1617720 1618090 1617959 1618090 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1619641 1620127 - ntar_669 1619641 1620127 1 1620127 1619641 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1620243 1621771 + orf19.6792 1620243 1621771 1 1620243 1621771 1620333 1621607 RRD1 orf19.14084|IPF20368.1|IPF10731.2|Contig4-2629_0011|orf6.8839|CA5913|CaO19.14084|CaO19.6792 Predicted ORF in Assemblies 19, 20 and 21; caspofungin induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1621292 1621646 - ntar_670 1621292 1621646 1 1621646 1621292 1621646 1621512 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1622116 1623251 + orf19.6791 1622116 1623251 1 1622116 1623251 1622371 1622781 HHT1 orf19.14083|IPF20438.1|IPF10733.1|Contig4-2629_0010|orf6.8840|CA5914|CaO19.6791|HHT3|CaO19.14083 Putative histone H3; reduced mRNA abundance detected in homozygous fkh2 null mutant; farnesol regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1623551 1623730 + ntar_671 1623551 1623730 1 1623551 1623730 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1623669 1626530 - orf19.6790 1623669 1626530 1 1626530 1623669 1626530 1623867 orf19.14082|IPF20308.1|IPF10735.2|Contig4-2629_0008|orf6.8841|CA5915|NGR1|CaO19.14082|CaO19.6790|IPF10735 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr3 1626906 1627532 + ntar_672 1626906 1627532 1 1626906 1627532 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1628188 1632073 + orf19.6789 1628188 1632073 1 1628188 1632073 1628276 1632073 orf19.14081|IPF20451.1|IPF19818.1|Contig4-1999_0005|Contig4-2629_0004|orf6.8842|CA5916|NUD1|CaO19.6789|CaO19.14081|IPF19818 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr3 1632257 1633201 + orf19.6788 1632257 1633201 1 1632257 1633201 1632380 1633117 orf19.14080|IPF20406.1|IPF8923.1|Contig4-1999_0004|orf6.8843|CA5917|CaO19.6788|CaO19.14080|IPF8923 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1633370 1634470 + orf19.6787 1633370 1634470 2 1633370|1633711 1633450|1634470 1633434 1634107 orf19.14079|IPF20443.1|IPF8924.2|Contig4-1999_0002|orf6.8844|CA5918|ERV14|CaO19.14079|CaO19.6787 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1634359 1636335 - orf19.6786 1634359 1636335 2 1636335|1636120 1636189|1634359 1636235 1634434 orf19.14078|IPF20351.1|IPF8926.2|Contig4-1999_0001|Contig4-1999_0006|orf6.8845|CA5919|CaO19.6786|CaO19.14078|IPF8926.3 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1636551 1637217 - orf19.6785 1636551 1637217 1 1637217 1636551 1637102 1636671 RPS12 orf19.14077|IPF20428.1|IPF8927.1|Contig4-2621_0003|orf6.8846|CA5920|CaO19.14077|CaO19.6785 Protein described as acidic ribosomal protein S12; regulated by Gcn4p, activated by Tbf1p; repressed under amino acid starvation (3-aminotriazole treatment); protein abundance is affected by URA3 expression in the CAI-4 strain background [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1637528 1637711 + ntar_673 1637528 1637711 1 1637528 1637711 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1637868 1639361 + orf19.6784 1637868 1639361 1 1637868 1639361 1638007 1639299 PGA32 orf19.14076|orf6.8847|IPF20370.1|IPF8930.1|Contig4-2621_0005|CA5921|CaO19.6784|CaO19.14076|IPF8930 Putative GPI-anchored protein of unknown function; transcriptionally regulated by iron; expression greater in high iron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1639384 1642147 - orf19.6783 1639384 1642147 1 1642147 1639384 1641701 1639689 orf19.14075|IPF20330.1|IPF8931.1|Contig4-2621_0007|Contig4-2621_0008|orf6.8848|CA5922|CaO19.14075|MRS6|CaO19.6783 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1642416 1642686 + ntar_674 1642416 1642686 1 1642416 1642686 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1642949 1643548 + ntar_675 1642949 1643548 1 1642949 1643548 1643184 1643447 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1643533 1645826 - orf19.6782 1643533 1645826 1 1645826 1643533 1645826 1643772 BMT1 orf19.14074|IPF20326.1|IPF2825.2|orf6.8849|CA5923|WRY4|CaO19.6782|CaO19.14074|IFQ2 Putative beta-mannosyltransferase, required for addition of the first beta-mannose residue to the acid-stable fraction of cell wall phosphopeptidomannan; member of a 9-gene family; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr3 1643849 1643988 + ntar_676 1643849 1643988 1 1643849 1643988 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1645851 1646137 + ntar_677 1645851 1646137 1 1645851 1646137 1645851 1646108 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1649580 1651412 - orf19.6781 1649580 1651412 2 1651412|1651134 1651297|1649580 1651365 1649785 orf19.14073|IPF20371.1|IPF2822.1|Contig4-2943_0009|orf6.8850|CA5924|CaO19.6781|ZFU2|CaO19.14073|IPF2822 Putative transcription factor with zinc finger DNA-binding motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1652487 1653661 + orf19.6780 1652487 1653661 1 1652487 1653661 1652564 1653421 MET8 orf19.14072|IPF20394.1|IPF2818.1|Contig4-2943_0012|orf6.8851|CA5925|CaO19.14072|CaO19.6780 Predicted ORF in Assemblies 19, 20 and 21; regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1653084 1654919 - orf19.6779 1653084 1654919 1 1654919 1653084 1654771 1653431 PRO2 orf19.14071|IPF20366.1|IPF2817.1|Contig4-2943_0013|Contig4-2943_0014|orf6.8852|CA5926|CaO19.14071|CaO19.6779 Predicted ORF in Assemblies 19, 20 and 21; regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1655223 1659426 + orf19.6778 1655223 1659426 1 1655223 1659426 1655336 1659298 orf19.14070|IPF20448.1|IPF2816.1|Contig4-2943_0017|orf6.8853|CA5927|CaO19.14070|DRS2|CaO19.6778|DRS22 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1660336 1661034 + orf19.6777 1660336 1661034 1 1660336 1661034 1660336 1661034 orf19.14069|IPF20412.1|IPF2815.1|Contig4-2943_0018|orf6.8854|CA5928|CaO19.14069|CaO19.6777|IPF2815 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1660529 1660754 - ntar_678 1660529 1660754 1 1660754 1660529 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1661342 1663179 + orf19.6776 1661342 1663179 1 1661342 1663179 1661373 1662875 GCD2 orf19.14068|IPF20358.1|IPF2813.1|Contig4-2943_0020|Contig4-2943_0021|orf6.8855|CA5929|CaO19.6776|CaO19.14068 Putative translation initiation factor; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1662885 1668512 - orf19.6773 1662885 1668512 1 1668512 1662885 1668512 1662933 ECM29 orf19.14064|orf19.14065|IPF20301.1|IPF2810.2|Contig4-3030_0004|orf6.8859|orf6.8858|CA5931|CA5930|orf19.6772|ECM29.3f|ECM29.exon2 Protein similar to S. cerevisiae Ecm29p; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1668605 1669509 - orf19.6771 1668605 1669509 1 1669509 1668605 1669384 1668695 UBI4 orf19.14063|UBI1|IPF20409.1|IPF2805.1|Contig4-3030_0005|orf6.8860|CA5932|CaO19.14063|CaO19.6771 Ubiquitin precursor (polyubiquitin), contains three tandem repeats of the ubiquitin peptide that are processed to individual units; transcription is induced by stress; mRNA found in yeast-form and mycelial cells at similar abundance [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1670259 1671659 - orf19.6770 1670259 1671659 1 1671659 1670259 1671371 1670415 orf19.14062|IPF20386.1|IPF2804.1|Contig4-3030_0008|orf6.8861|CA5933|ENT4|CaO19.6770|CaO19.14062|IPF2804 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1670570 1670834 + ntar_679 1670570 1670834 1 1670570 1670834 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1672814 1673106 - ntar_680 1672814 1673106 1 1673106 1672814 1672975 1672814 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1673117 1675526 + orf19.6769 1673117 1675526 1 1673117 1675526 1673322 1675472 orf19.14061|IPF20321.1|IPF2802.1|Contig4-3030_0011|Contig4-3030_0012|orf6.8862|CA5934|CaO19.14061|CaO19.6769|IPF2802 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1675709 1676993 + orf19.6766 1675709 1676993 1 1675709 1676993 1675736 1676926 orf19.14058|IPF20375.1|IPF2798.1|Contig4-3030_0014|orf6.8865|CA5935|NOP13|CaO19.6766|CaO19.14058|IPF2798 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1676924 1680957 - orf19.6763 1676924 1680957 1 1680957 1676924 1680819 1677226 SLK19 orf19.14055|orf6.8869|IPF2795|KER1|IPF20454.1|IPF2795.1|Contig4-2621_0012|Contig4-3030_0015|CA5936|CaO19.6763|CaO19.14055 Alkaline-induced protein of plasma membrane; affects cell aggregation, cell wall; similar to S. cerevisiae Slk19p (a kinetochore protein with roles in mitosis, meiosis); required for wild-type virulence in mouse; macrophage-downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1682292 1682538 - ntar_681 1682292 1682538 1 1682538 1682292 1682450 1682292 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1682832 1685135 + orf19.6760 1682832 1685135 1 1682832 1685135 1683075 1685135 MDS3 orf19.14052|IPF20324.1|IPF2784.2|Contig4-3030_0020|orf6.8871|CA5937|CaO19.14052|CaO19.6760|IPF2784 Component of an alkaline pH-response pathway distinct from the Rim101p pathway, required for growth and hyphal formation at pH 9 and for full virulence in a mouse model of systemic infection; has a role in chlamydospore formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1685238 1687436 + orf19.6759 1685238 1687436 1 1685238 1687436 1685238 1687226 orf19.14051|IPF20325.1|IPF3482.2|Contig4-2141_0007|orf6.8872|CA5938|CaO19.6759|CaO19.14051|IPF3481 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1687588 1688685 + orf19.6758 1687588 1688685 1 1687588 1688685 1687707 1688576 orf19.14050|IPF20398.1|IPF3484.1|Contig4-2141_0004|orf6.8873|CA5939|CaO19.6758|CaO19.14050|IPF3484 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1688962 1689973 + orf19.6757 1688962 1689973 1 1688962 1689973 1689013 1689900 GCY1 orf19.14049|IPF20388.1|IPF3485.1|Contig4-2141_0004|Contig4-2255_0006|orf6.8874|CA5940|CaO19.14049|CaO19.6757|IPF3485 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to toxic ergosterol analog; farnesol-downregulated; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1690092 1690283 - ntar_682 1690092 1690283 1 1690283 1690092 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1690112 1691116 + orf19.6756 1690112 1691116 1 1690112 1691116 1690160 1691053 orf19.14048|IPF20393.1|IPF3486.1|Contig4-3006_0001|orf6.8875|CA5941|CaO19.6756|CaO19.14048|IPF3486 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1690713 1691038 - ntar_683 1690713 1691038 1 1691038 1690713 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1691232 1693129 + orf19.6755 1691232 1693129 1 1691232 1693129 1691329 1692930 orf19.14047|IPF20355.1|IPF3488.1|Contig4-3006_0003|orf6.8876|CA5942|CaO19.6755|DLD2|CaO19.14047 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1693713 1694400 + orf19.6754 1693713 1694400 1 1693713 1694400 1693773 1694354 orf19.14046|IPF20417.1|IPF3490.2|Contig4-3006_0006|orf6.8877|CA5943|CaO19.14046|CaO19.6754|IPF3490 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1693993 1694340 - ntar_684 1693993 1694340 1 1694340 1693993 1694185 1694051 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1694605 1695505 + orf19.6753 1694605 1695505 2 1694605|1694816 1694736|1695505 1694721 1695378 orf19.14045|IPF20418.1|IPF3491.1|Contig4-3006_0007|orf6.8878|CA5944|CaO19.6753|CaO19.14045|IPF3491 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1695350 1696193 - orf19.6752 1695350 1696193 1 1696193 1695350 1696153 1695449 orf19.14044|IPF20402.1|IPF3492.1|Contig4-3006_0008|orf6.8879|CA5945|RSM10|CaO19.14044|CaO19.6752|IPF3492 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1696320 1697254 + orf19.6751 1696320 1697254 1 1696320 1697254 1696346 1697227 orf19.14043|IPF20389.1|IPF3493.1|Contig4-3006_0009|orf6.8880|CA5946|TRM7|CaO19.6751|CaO19.14043|IPF3493 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1697218 1699107 - orf19.6749 1697218 1699107 1 1699107 1697218 1699061 1697277 KRS1 orf19.14041|IPF20344.1|IPF3495.1|Contig4-3006_0010|orf6.8882|CA5947|CaO19.14041|CaO19.6749 Putative tRNA-Lys synthetase; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophages; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1699209 1700511 + orf19.6748 1699209 1700511 1 1699209 1700511 1699360 1700346 orf19.14040|IPF20385.1|IPF3496.1|Contig4-3006_0011|orf6.8883|CA5948|CaO19.14040|CaO19.6748|IPF3496 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1700559 1701888 + orf19.6747 1700559 1701888 2 1700559|1700690 1700622|1701888 1700608 1701604 orf19.14039|IPF20391.1|IPF3498.1|Contig4-3006_0012|orf6.8884|CA5949|CaO19.6747|CaO19.14039|IPF3498 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1702019 1702909 + orf19.6745 1702019 1702909 1 1702019 1702909 1702073 1702819 TPI1 orf19.14037|TPIS|IPF20404.1|IPF3499.1|Contig4-3006_0013|orf6.8886|CA5950|CaO19.14037|CaO19.6745 Triose-phosphate isomerase; glycolysis/gluconeogenesis; antigenic in mouse or human; mutation affects filamentous growth; biofilm-induced; macrophage-downregulated protein; detected by mass spec in exponential and stationary phase culture [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1702752 1703919 - orf19.6744 1702752 1703919 1 1703919 1702752 1703806 1702835 orf19.14036|IPF20382.1|IPF3500.1|Contig4-3006_0014|orf6.8887|CA5951|CaO19.14036|CaO19.6744|IPF3500 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1704208 1706959 + orf19.6742 1704208 1706959 1 1704208 1706959 1704388 1706694 orf19.14034|IPF20315.1|IPF3503.1|Contig4-3006_0018|orf6.8889|CA5952|CaO19.14034|FCP1|CaO19.6742|IPF3503 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1707635 1709232 + orf19.6741 1707635 1709232 1 1707635 1709232 1707757 1709049 orf19.14033|IPF20373.1|IPF3506.2|Contig4-3006_0020|orf6.8890|CA5953|CaO19.6741|CaO19.14033|IPF3506 Predicted ORF in Assemblies 19, 20 and 21; regulated by Nrg1p, Tup1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1709279 1710747 + orf19.6740 1709279 1710747 1 1709279 1710747 1709407 1710747 orf19.14032|IPF20367.1|IPF3508.1|Contig4-3034_0024|Contig4-3034_0026|orf6.8891|CA5954|CaO19.14032|PRP19|CaO19.6740|IPF3508 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1710853 1712826 + orf19.6739 1710853 1712826 1 1710853 1712826 1710894 1712744 orf19.14031|IPF20339.1|IPF3510.1|Contig4-3034_0023|orf6.8892|CA5955|CaO19.6739|CaO19.14031|IPF3510 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1713093 1714827 + orf19.6738 1713093 1714827 2 1713093|1713359 1713264|1714827 1713200 1714754 VAN1 orf19.14030|IPF20361.1|IPF3512.2|Contig4-3034_0022|orf6.8893|CA5956|CaO19.14030|CaO19.6738|IPF3512.1 Member of Mnn9p family; similar to S. cerevisiae Van1p; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1714834 1715160 - snr52 1714834 1715160 1 1715160 1714834 1715013 1714855 SNR52 snR52.2 Putative ortholog of S. cerevisiae C/D snoRNA with role in 2'-O-methylation of 5S rRNA; gene transcribed by RNA Pol III [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1715762 1715834 + tr(ucu)5 1715762 1715834 1 1715762 1715834 tR(UCU)5.2 tRNA-Arg predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1715843 1715930 + tf(gaa)5 1715843 1715930 2 1715843|1715895 1715879|1715930 tF(GAA)5.2 tRNA-Phe predicted by tRNAscan-SE; has atypical tertiary T15A48 basepair (rather than R15Y48 basepair) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1715996 1717273 - orf19.6737 1715996 1717273 1 1717273 1715996 1716965 1716099 orf19.14029|IPF6050|IPF20392.1|IPF6050.1|Contig4-3034_0021|orf6.6886|CA4360|CaO19.14029|CaO19.6737 Protein not essential for viability; greater mRNA abundance observed in a cyr1, ras1, or efg1 homozygous null mutant than in wild type; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1717569 1718066 + ntar_685 1717569 1718066 1 1717569 1718066 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1719264 1721374 - orf19.6736 1719264 1721374 1 1721374 1719264 1721338 1719449 orf19.14028|IPF20338.1|IPF6054.1|Contig4-3034_0015|Contig4-3034_0016|orf6.6885|CA4359|FMP38|CaO19.6736|CaO19.14028|IPF6054 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1729766 1732553 + orf19.6734 1729766 1732553 1 1729766 1732553 1730059 1732305 TCC1 orf19.14026|IPF20318.1|IPF6067.1|Contig4-3034_0002|orf6.6883|CA4358|CaO19.14026|CaO19.6734|IPF6067 Protein involved in regulation of filamentous growth and virulence; interacts with Tup1p; acts in transcriptional regulation of hypha-specific genes; contains 4 tetratricopeptide repeat (TPR) motifs; flucytosine repressed; Tbp1p-activated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1732343 1733421 - orf19.6732 1732343 1733421 1 1733421 1732343 1733288 1732422 orf19.14024|IPF20396.1|IPF19800.1|orf6.6881|CA4357|CaO19.6732|CaO19.14024|IPF19800 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1733495 1734002 + orf19.6731.1 1733495 1734002 1 1733495 1734002 1733543 1733812 IPF20303.1|IPF3651.2|Contig4-1872_0001|CA4356|IPF3651 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1734033 1734547 + orf19.6731 1734033 1734547 1 1734033 1734547 1734057 1734389 orf19.14023|IPF20437.1|IPF3650.1|Contig4-1872_0003|orf6.6880|CaO19.14023|CaO19.6731 Predicted ORF in Assemblies 19, 20 and 21; transcription is repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1734177 1734718 - ntar_686 1734177 1734718 1 1734718 1734177 1734718 1734482 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1734745 1735395 + orf19.6730 1734745 1735395 1 1734745 1735395 1734745 1735395 orf19.14022|IPF20408.1|IPF3649.1|Contig4-1872_0004|orf6.6879|CA4355|CaO19.6730|CaO19.14022|IPF3649 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1735431 1739249 + orf19.6729 1735431 1739249 1 1735431 1739249 1735431 1739156 TIP120 orf19.14021|IPF3647|IPF20453.1|IPF3647.2|Contig4-1872_0006|orf6.6878|CA4354|CaO19.6729|CaO19.14021 Protein similar to human and rat TBP-binding transcription regulatory protein; not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1739073 1740504 - orf19.6727 1739073 1740504 1 1740504 1739073 1740504 1739191 RIT1 orf19.14019|IPF20372.1|IPF3645.1|orf6.6876|CA4353|CaO19.6727|CaO19.14019|IPF3645 Putative initiator tRNA methionine ribosyltransferase; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1740573 1741571 - orf19.6726 1740573 1741571 1 1741571 1740573 1741571 1740573 orf19.14018|IPF20383.1|IPF3642.1|Contig4-3073_0021|orf6.6875|CA4352|CaO19.6726|SPT2|CaO19.14018|IPF3642 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1741696 1743425 - orf19.6724 1741696 1743425 1 1743425 1741696 1743279 1741747 FUM12 orf19.14016|orf19.14017|orf6.6873|FUM12.3|IPF20395.1|IPF3640.2|IPF20327.1|IPF18225.1|IPF20416.1|IPF3641.2|orf6.6874|CA4349|CA4350|CA4351|orf19.6724.1|orf19.6725|FUM1|CaO19.14016|CaO19.6724|FUM12.5f Protein described as similar to fumarate hydratase, enzyme of citric acid cycle; fluconazole-downregulated; downregulated by Efg1p; transcriptionally regulated by iron; expression greater in high iron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1743535 1745593 - orf19.6723 1743535 1745593 1 1745593 1743535 1745592 1743535 orf19.14015|IPF20328.1|IPF3638.2|orf6.6872|CA4348|CaO19.6723|CaO19.14015|IPF3638 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=C scenario_last_exon=C] Ca21chr3 1745689 1747993 + orf19.6722 1745689 1747993 1 1745689 1747993 1745729 1747858 orf19.14014|IPF20323.1|IPF3636.2|orf6.6871|RAD4|CA4347|CaO19.6722|CaO19.14014|IPF3636 Predicted ORF in Assemblies 19, 20 and 21; similar to S. cerevisiae Rad4p; down-regulation associated with azole resistance [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1748319 1749083 + orf19.6720 1748319 1749083 1 1748319 1749083 1748343 1749083 orf19.14012|IPF20405.1|IPF3634.1|Contig4-2901_0002|orf6.6869|CA4346|YDR090C|CaO19.6720|CaO19.14012|IPF3634 Predicted ORF in Assemblies 19, 20 and 21; similar to S. cerevisiae Ydr090cp; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr3 1748380 1749104 - ntar_687 1748380 1749104 1 1749104 1748380 1748773 1748600 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1749192 1754214 + orf19.6719 1749192 1754214 2 1749192|1749258 1749200|1754214 1749198 1754030 orf19.14011|IPF20425.1|IPF3633.1|Contig4-2901_0003|Contig4-2901_0006|orf6.6868|CA4345|CaO19.14011|HIR3|CaO19.6719|IPF3633.3f|IPF3633.3 Predicted ORF in Assemblies 19, 20 and 21; intron annotated in Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1753952 1754972 - orf19.6718 1753952 1754972 2 1754972|1754749 1754805|1753952 1754854 1754047 orf19.14010|IPF20410.1|IPF3631.1|Contig4-2901_0007|orf6.6867|CA4344|CaO19.6718|CaO19.14010|IPF3631 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1754940 1755789 + orf19.6717 1754940 1755789 1 1754940 1755789 1754955 1755734 orf19.14009|IPF20401.1|IPF3630.1|Contig4-2901_0009|orf6.6866|CA4343|CaO19.14009|CaO19.6717|IPF3630 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1755830 1757505 + orf19.6716 1755830 1757505 1 1755830 1757505 1755847 1757271 ABD1 orf19.14008|CCM1|IPF20363.1|IPF3629.1|Contig4-2901_0011|orf6.6865|CA4342|CaO19.6716|CaO19.14008|IPF3629 RNA (guanine-N7-)-methyltransferase, SAM-dependent; methylates mRNA 5' cap; binds phosphorylated RNA Pol II C-terminal domain peptide; does not bind mRNA TPase and mRNA GTase (Cet1p and Cgt1p); functional homolog of S. cerevisiae Abd1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1757716 1757907 - ntar_688 1757716 1757907 1 1757907 1757716 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1757970 1758278 - orf19.6715 1757970 1758278 1 1758278 1757970 1758278 1757970 orf19.14007|IPF20459.1|IPF27667.1|orf6.6864|CaO19.14007|CaO19.6715 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1761423 1763172 + orf19.6713 1761423 1763172 1 1761423 1763172 1761921 1763126 orf19.14005|IPF20377.1|IPF3624.1|orf6.6862|CA4341|CaO19.14005|CaO19.6713|IPF3624 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1763317 1765320 + orf19.6712 1763317 1765320 1 1763317 1765320 1763320 1765296 orf19.14004|IPF20331.1|IPF3621.2|Contig4-1879_0003|orf6.6861|CA4340|CaO19.6712|CaO19.14004|IPF3621 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1765389 1767029 + orf19.6710 1765389 1767029 1 1765389 1767029 1765416 1766753 UTP9 orf19.14002|IPF20369.1|IPF3618.2|Contig4-1879_0002|orf6.6859|CA4339|CaO19.6710|CaO19.14002|IPF3618 Predicted ORF in Assemblies 19, 20 and 21; decreased expression observed in an ssr1 homozygous null mutant; decreased expression in response to prostaglandins; physically interacts with TAP-tagged Nop1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1766710 1767672 - orf19.6709 1766710 1767672 1 1767672 1766710 1767672 1766746 orf19.14001|IPF20387.1|IPF3616.3|Contig4-1879_0001|orf6.6858|CA4338|CaO19.14001|CaO19.6709|IPF3616.3eoc|IPF3616|IPF3616.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr3 1767671 1767897 + ntar_689 1767671 1767897 1 1767671 1767897 1767671 1767841 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1767930 1768875 - orf19.6170 1767930 1768875 1 1768875 1767930 1768853 1767942 IPF3418.1|orf6.5391|CA3193|BIK1|CaO19.6170|IPF3418.5eoc|IPF3418 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1768943 1771568 - orf19.6171 1768943 1771568 1 1771568 1768943 1771526 1768974 IPF3423.1|Contig4-3079_0004|orf6.5392|CA3194|CaO19.6171|NUP159|IPF3425 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1772150 1773384 + orf19.6173 1772150 1773384 1 1772150 1773384 1772316 1773323 STD1 IPF3426.1|Contig4-3079_0005|orf6.5394|CA3195|CaO19.6173|IPF3426 Protein described as transcription factor involved in control of glucose-regulated gene expression; repressed by Rgt1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1773047 1773950 - orf19.6175 1773047 1773950 1 1773950 1773047 1773948 1773325 IPF3428.1|Contig4-3079_0006|orf6.5396|CA3196|CaO19.6175|IPF3428 Predicted ORF in Assemblies 19, 20 and 21; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1773991 1775485 - orf19.6176 1773991 1775485 1 1775485 1773991 1775464 1774025 SEC61 orf6.5397|IPF3431.1|Contig4-3079_0009|CA3197|CaO19.6176 Essential protein; expected to act in protein translocation from the endoplasmic reticulum: similar to S. cerevisiae Sec61p; chimeric mutant partially functionally complements S. cerevisiae sec61 defects; 10 transmembrane regions predicted [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1775667 1776077 + orf19.6177 1775667 1776077 1 1775667 1776077 1775684 1776010 IPF3432.1|Contig4-3079_0010|orf6.5398|CA3198|CaO19.6177|IPF3432 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1776141 1777192 + orf19.6178 1776141 1777192 1 1776141 1777192 1776158 1777153 FBP1 IPF3435.1|Contig4-3079_0011|orf6.5399|CA3199|CaO19.6178 Fructose-1,6-bisphosphatase, a key enzyme of gluconeogenesis; involved in the carbohydrate metabolism; regulated by Efg1p, Ssn6p; upregulated upon phagocytosis, effecting switch from glycolysis to gluconeogenesis in macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1776233 1776925 - orf19.6179 1776233 1776925 1 1776925 1776233 1776925 1776233 IPF3434.1|orf6.5400 ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1777228 1778538 + orf19.6180 1777228 1778538 1 1777228 1778538 1777228 1778538 IPF3439.1|Contig4-3079_0015|orf6.5401|YDL054C|CA3200|MCH1|CaO19.6180|IPF3439 Protein similar to Pichia anomala YDL054c and S. cerevisiae Ydl054cp; transmembrane regions predicted [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1778398 1780663 - orf19.6182 1778398 1780663 1 1780663 1778398 1780657 1778525 ZCF34|IPF3443.1|Contig4-3079_0016|orf6.5403|CA3201|CaO19.6182|IPF3444.3f Putative transcription factor with zinc cluster DNA-binding motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1778654 1778959 + orf19.6181 1778654 1778959 1 1778654 1778959 1778654 1778959 orf6.5402 [NOT TRANSCRIBED?] ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1780669 1781127 - orf19.6184 1780669 1781127 1 1781127 1780669 1781127 1780669 IPF3444.1|Contig4-3079_0017|orf6.5405|CA3202|CaO19.6184|IPF3444.5f Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1781096 1781493 + orf19.6183 1781096 1781493 1 1781096 1781493 1781190 1781456 IPF3445.1|orf6.5404|CA3203|CaO19.6183|TIM8|IPF3445 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1781415 1782517 - orf19.6186 1781415 1782517 1 1782517 1781415 1782517 1781453 IPF3446.1|Contig4-3079_0019|orf6.5407|CA3204|CaO19.6186|IPF3446 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr3 1782319 1784424 + orf19.6187 1782319 1784424 2 1782319|1783357 1783304|1784424 1782399 1784424 IPF3454.2|Contig4-3079_0021|orf6.5408|CA3206|CaO19.6187|IPF3454 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1782399 1783322 + orf19.6185 1782399 1783322 1 1782399 1783322 1782399 1783322 IPF3448|IPF3448.1|Contig4-3079_0020|orf6.5406|CA3205|IND1|CaO19.6185 Protein not essential for viability [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1783353 1783670 - orf19.6188 1783353 1783670 1 1783670 1783353 1783670 1783353 orf6.5409|CaO19.6188 [NOT TRANSCRIBED?] ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1784464 1785266 + orf19.6189 1784464 1785266 1 1784464 1785266 1784472 1785185 IPF3456.2|Contig4-3079_0022|orf6.5410|CA3207|CaO19.6189|FMP22|IPF3456 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr3 1785155 1786311 - orf19.6190 1785155 1786311 1 1786311 1785155 1786287 1785199 SRB1 VIG9|PSA1|IPF3458.1|Contig4-3079_0023|orf6.5411|CA3208|CaO19.6190 Essential GDP-mannose pyrophosphorylase; synthesizes GDP-mannose for protein glycosylation; functional homolog of S. cerevisiae Psa1p; at surface of yeast-form, not hyphal, cells; alkaline upregulated; induced on adherence to polystyrene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr3 1786471 1786870 + ntar_690 1786471 1786870 1 1786471 1786870 1786471 1786737 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1787316 1787612 - ntar_691 1787316 1787612 1 1787612 1787316 1787504 1787316 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1787715 1788224 - orf19.6191 1787715 1788224 1 1788224 1787715 1788224 1787715 TLO8 IPF3460.1|IPF3461.1|Contig4-2278_0004|Contig4-3079_0026|orf6.5412|CA3210|TLO8b|CaO19.6191|CTA223|CTA210.5f Member of a family of telomere-proximal genes of unknown function; may be spliced in vivo [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr3 1788079 1788399 + ntar_692 1788079 1788399 1 1788079 1788399 1788079 1788309 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1793516 1794531 + ntar_693 1793516 1794531 1 1793516 1794531 1793789 1794034 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1794520 1794926 + ntar_694 1794520 1794926 1 1794520 1794926 1794520 1794738 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1795409 1796005 + ntar_695 1795409 1796005 1 1795409 1796005 1795496 1795678 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1795919 1796346 - orf19.6192 1795919 1796346 1 1796346 1795919 1796320 1795919 IPF19977.1|Contig4-2081_0001|orf6.5413|CA3211|CaO19.6192|IPF19977 Predicted ORF in Assemblies 19, 20 and 21; Plc1p-regulated; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr3 1796658 1797334 - ntar_696 1796658 1797334 1 1797334 1796658 1797168 1797013 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr3 1797817 1798258 + ntar_697 1797817 1798258 1 1797817 1798258 1797935 1798165 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 983 1660 + orf19.362 983 1660 1 983 1660 983 1660 TLO9 orf19.7994|IPF26943.1|IPF10947.1|orf6.321|CA0050|CTA212|CaO19.362|CaO19.7994|CTA25 Member of a family of telomere-proximal genes of unknown function [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr4 2146 2572 - ntar_698 2146 2572 1 2572 2146 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 2837 3916 + orf19.364 2837 3916 1 2837 3916 2845 3891 orf19.7996|IPF19887.2|IPF29859.1|Contig4-2956_0004|orf6.2055|orf6.323|CA0876|VMA6|CaO19.364|IPF19887.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 3812 4952 - orf19.366 3812 4952 1 4952 3812 4904 3894 orf19.7997|IPF10954.1|IPF29860.1|Contig4-2956_0003|orf6.2056|CA6174|RAD17|CaO19.366 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 5020 7444 + orf19.367 5020 7444 1 5020 7444 5033 7435 CNH1 orf19.8001|IPF10959.2|IPF29854.1|Contig4-2956_0001|orf6.2060|orf6.2059|CA0877|CaO19.367|CA0878|CNH1.3f|IPF18845.1|CNH1.5f Na+/H+ antiporter; required for wild-type growth, cell morphology, and virulence in a mouse model of systemic infection; not transcriptionally regulated by NaCl; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 7507 8355 + orf19.371 7507 8355 1 7507 8355 7507 8355 orf19.8003|IPF19542.1|IPF19543.2|orf6.2062|CA0879|CaO19.371|IPF19542.5f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 8369 9107 + orf19.372 8369 9107 1 8369 9107 8369 8995 orf19.8004|IPF19494.2|IPF16966.2|orf6.2063|orf6.7|CA0880|CaO19.8004|CaO19.372|IPF19542.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 8784 11324 - orf19.374 8784 11324 1 11324 8784 11315 8937 orf19.8006|IPF16965.2|IPF29855.1|orf6.2065|CA0881|CaO19.374|CaO19.8006|IPF16965 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 11383 12630 - orf19.376 11383 12630 1 12630 11383 12630 11383 orf19.8008|IPF26941.1|IPF12110.2|Contig4-1877_0001|orf6.2067|orf6.65|CA0008|CaO19.376|BDA1|IPF12110 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 12792 14307 + orf19.377 12792 14307 2 12792|12955 12902|14307 12792 14307 PHR3 orf19.13077|orf19.8010|IPF12107.2|IPF12108.3|IPF21539.1|IPF18452.2|Contig4-1877_0003|Contig4-2202_0005|orf6.2069|orf6.66|orf6.4501|CA0882|orf19.5632|CaO19.8010|CaO19.377 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21; fungal-specific (no human or murine homolog) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 13063 15704 - orf19.5633 13063 15704 1 15704 13063 15704 14304 orf19.13078|orf19.8011|IPF21530.1|IPF12105.2|Contig4-2202_0002|orf6.2070|orf6.4502|CA2555|orf19.378|CaO19.5633|CaO19.13078|IPF12105 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr4 15790 17454 - orf19.5634 15790 17454 1 17454 15790 17454 15790 FRP1 orf19.13079|orf6.4503|FRE5|IPF21526.1|IPF12102.2|Contig4-2202_0003|Contig4-2202_0004|CA2556|CaO19.13079|CaO19.5634 Predicted ferric reductase; gene alkaline-induced directly by Rim101p; iron-chelation-induced by CCAAT-binding factor (with Hap43p); fluconazole-downregulated; ciclopirox olamine induced; colony morphology-related gene regulation by Ssn6p [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 16273 16938 + ntar_699 16273 16938 1 16273 16938 16622 16750 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 17106 17357 + ntar_700 17106 17357 1 17106 17357 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 17801 18502 + orf19.5635 17801 18502 1 17801 18502 17801 18460 PGA7 orf19.13080|IPF21547.1|IPF12101.1|CRW3|Contig4-1570_0002|orf6.4504|CA2557|CaO19.5635|CaO19.13080|IPF12101 Protein described as a putative precursor of a hyphal surface antigen; putative GPI-anchor; induced by ciclopirox olamine, ketoconazole, or by Rim101p at pH 8; regulated during planktonic growth; induced during cell wall regeneration [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr4 19655 20457 + orf19.5636 19655 20457 1 19655 20457 19713 20438 RBT5 orf19.13081|orf6.4505|IPF21544.1|IPF19952.1|CA2558|CaO19.5636|CaO19.13081 GPI-anchored cell wall protein involved in hemoglobin utilization; expression is regulated by Rfg1p, Rim101p, Tbf1p, iron; repressed by Sfu1p, Hog1p, Tup1p; induced by serum, alkaline pH, ketoconazole, ciclopirox olamine [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr4 21032 23708 - orf19.5639 21032 23708 1 23708 21032 23694 21178 HIS4 orf19.13084|IPF21508.1|IPF12359.2|Contig4-2558_0003|orf6.4508|CA2559|CaO19.13084|CaO19.5639 Multifunctional enzyme that catalyzes three steps of histidine biosynthesis, with phosphoribosyl-AMP cyclohydrolase, phosphoribosyl-ATP diphosphatase, and histidinol dehydrogenase activities; required for wild-type adhesion to human calls [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 23796 25667 - orf19.5640 23796 25667 1 25667 23796 25631 23853 PEX5 orf19.13085|IPF21521.1|IPF12357.2|Contig4-2558_0005|orf6.4509|CA2560|CaO19.5640|CaO19.13085 Protein of the Pex5p family; required for PTS1-mediated peroxisomal protein import, fatty acid beta-oxidation; similar to S. cerevisiae Pas10p peroxisomal targeting receptor; macrophage/pseudohyphal-repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 25836 27213 - orf19.5641 25836 27213 1 27213 25836 27186 25876 CAR2 orf19.13086|IPF21531.1|IPF12355.2|Contig4-2558_0006|orf6.4510|CaO19.5641|CaO19.13086|CA2561 Alkaline upregulated; mutation confers hypersensitivity to toxic ergosterol analog, and to amphotericin B [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 27469 28049 + orf19.5642 27469 28049 1 27469 28049 27530 27943 orf19.13087|IPF21553.1|IPF19953.1|Contig4-2558_0008|orf6.4511|CA2562|CaO19.13087|CaO19.5642|IPF19953 Predicted ORF in Assemblies 19, 20 and 21; shows colony morphology-related gene regulation by Ssn6p; greater mRNA abundance observed in a cyr1 homozygous null mutant than in wild type [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 28113 29696 + orf19.5643 28113 29696 1 28113 29696 28147 29691 ECM7 orf19.13088|IPF21524.1|IPF12129.2|Contig4-2558_0010|orf6.4512|CA2563|CaO19.13088|CaO19.5643 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 29708 30728 + orf19.5644 29708 30728 1 29708 30728 29746 30663 orf19.13089|IPF21540.1|IPF12127.2|Contig4-2558_0011|orf6.4513|CA2564|CaO19.5644|CaO19.13089|IPF12127 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 30567 32126 - orf19.5645 30567 32126 1 32126 30567 31982 30660 MET15 orf19.13090|MET25|IPF21534.1|IPF12125.2|orf6.4514|CA2565|CaO19.13090|CaO19.5645 O-acetylhomoserine O-acetylserine sulfhydrylase; involved in sulfur amino acid biosynthesis; immunogenic; Hog1p, biofilm, possibly adherence-induced; brown colony color of homozygous mutant in Pb(2+) medium is visual selection marker [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 32456 33407 + orf19.5646 32456 33407 1 32456 33407 32585 33277 orf19.13091|IPF21549.1|IPF12122.2|Contig4-2460_0002|orf6.4515|CA2566|CaO19.5646|CaO19.13091|IPF12122 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 33291 34818 - orf19.5647 33291 34818 2 34818|34461 34541|33291 34763 33383 SUB2 orf19.13092|IPF18224.2|IPF12120.1|Contig4-2460_0004|orf6.4516|CA2568|orf19.5647.2|CA2567|SUB2.3f Transcription is regulated by Mig1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 34782 35390 + orf19.5648 34782 35390 1 34782 35390 34782 35390 orf19.13093|IPF12119.3|IPF12117.1|Contig4-2460_0008|orf6.4517|orf6.6888|CA2569|CaO19.5648|IPF12117 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 35314 36258 - orf19.5650 35314 36258 1 36258 35314 36235 35411 PRO3 orf19.13095|IPF21542.1|IPF12114.2|Contig4-2460_0009|orf6.4519|orf6.6890|CA2570|CaO19.5650 Protein induced during the mating process; alkaline upregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 35408 35975 + orf19.5649 35408 35975 1 35408 35975 35436 35975 IPF18222.2|IPF12115.2|orf6.4518|orf6.6889 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 36604 39162 + orf19.5651 36604 39162 1 36604 39162 36910 39081 orf19.13096|IPF16104.2|IPF18451.2|Contig4-3054_0028|orf6.4520|orf6.6891|CA4361|CaO19.5651|IPF16104 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 39408 41474 + orf19.5653 39408 41474 2 39408|39994 39583|41474 39465 41389 ATP2 orf19.13098|IPF21527.1|IPF5264.1|Contig4-3054_0025|orf6.6893|CA4362|CaO19.5653|CaO19.13098 Protein described as a similar to F1 beta subunit of F1F0 ATPase complex; antigenic in human, mouse; transcription upregulated in response to ciclopirox olamine; flucytosine induced; caspofungin repressed; macrophage/pseudohyphal-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 41620 43155 + orf19.5654 41620 43155 2 41620|41722 41668|43155 41651 43041 orf19.13099|IPF21528.1|IPF5265.1|Contig4-3054_0024|orf6.6894|CaO19.13099|STE24|CaO19.5654|CA4363 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 43142 44715 - orf19.5655 43142 44715 3 44715|43992|43847 44079|43989|43142 44715 43184 orf19.13100|orf19.13101|IPF21550.1|IPF5266.2|Contig4-3054_0022|Contig4-3054_0023|orf6.6895|orf6.6896|CA4365|orf19.5656|IPF5268|CA4364|IPF5268.exon2|IPF5268.exon1|IPF5268.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGDmod orf_changed=false scenario_first_exon=Z scenario_last_exon=I] Ca21chr4 45028 48100 - orf19.5657 45028 48100 1 48100 45028 48100 45137 SWI1 orf19.13102|IPF21507.1|IPF5271.2|Contig4-3054_0020|orf6.6897|CA4366|SWC1|CaO19.5657|CaO19.13102 Protein involved in transcription regulation; ortholog of S. cerevisiae Swi1p, which is a subunit of the SWI/SNF chromatin remodeling complex; interacts with Snf2p; SWI/SNF complex is essential for hyphal growth and virulence [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 48307 49314 - orf19.5658 48307 49314 1 49314 48307 49314 48307 MNN10 orf19.13103|IPF21536.1|IPF5272.1|Contig4-3054_0018|orf6.6898|CA4367|CaO19.13103|CaO19.5658 Protein with similarity to mannosyltransferases; fungal-specific (no human or murine homolog) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 49344 49995 + ntar_701 49344 49995 1 49344 49995 49344 49664 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 49495 50546 - orf19.5660 49495 50546 2 50546|50402 50473|49495 50512 49534 orf19.13105|IPF21541.1|IPF5275.1|Contig4-3054_0014|Contig4-3054_0015|orf6.6900|CA4368|PEX10|CaO19.5660|CaO19.13105|PEX10.3f|PEX10.3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 50662 51271 - orf19.5660.1 50662 51271 1 51271 50662 51211 50930 IPF21567.1|IPF5277.1|Contig4-3054_0013|CA4369|TIM11 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 51470 52603 + orf19.5661 51470 52603 1 51470 52603 51477 52574 PTC7 orf19.13106|YHR76|IPF21537.1|IPF5279.1|Contig4-3054_0012|orf6.6901|CA4370|CaO19.5661|CaO19.13106|IPF5279 Protein phosphatase, type 2C; has S/T phosphatase activity, Mn2+/Mg2+ dependent; predicted membrane-spanning segment and mitochondrion-targeting signal [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr4 52648 54077 + orf19.5662 52648 54077 1 52648 54077 52683 54020 PEP7 orf19.13107|IPF21533.1|IPF5281.1|Contig4-3054_0011|orf6.6902|CA4371|VAC1|CaO19.5662|CaO19.13107 Vesicle transport protein; acts in endosomal transport; roles in metal ion resistance, virulence, adhesion, hyphal growth, chlamydospore formation; similar to S. cerevisiae Pep7p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 54019 55755 - orf19.5663 54019 55755 1 55755 54019 55317 54082 FSP1|orf19.13108|IPF21535.1|IPF5282.1|Contig4-3054_0010|orf6.6903|CA4372|CaO19.5663|CaO19.13108|IPF5282 Protein of unknown function; null mutation confers resistance to azoles and terbinafine; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 56428 58486 + orf19.5664 56428 58486 1 56428 58486 56584 58407 HOF1 orf19.13109|IPF21517.1|IPF5287.2|Contig4-3054_0008|orf6.6904|CA4373|CaO19.13109|CaO19.5664|IPF5287 Protein not essential for viability; similar to S. cerevisiae Hof1p, which is a protein localized to the bud neck and required for cytokinesis; periodic mRNA expression, peak at cell-cycle G2/M phase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 58132 58367 - ntar_702 58132 58367 1 58367 58132 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 58542 59641 + orf19.5665 58542 59641 1 58542 59641 58588 59571 orf19.13110|IPF21538.1|IPF5288.2|Contig4-3054_0007|orf6.6905|CA4374|CaO19.5665|CaO19.13110|IPF5288 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 59685 60336 + orf19.5666 59685 60336 1 59685 60336 59717 60157 orf19.13111|IPF21552.1|IPF11309.2|Contig4-3054_0006|orf6.6906|CA4375|CaO19.13111|CaO19.5666|IPF11309 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 60908 63422 + orf19.5667 60908 63422 1 60908 63422 60947 63340 MNR2 orf19.13112|IPF21510.1|IPF11307.2|Contig4-3054_0004|orf6.6907|CA4376|CaO19.5667|CaO19.13112|IPF11307 Putative ion transporter; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 63094 63483 - ntar_703 63094 63483 1 63483 63094 63483 63313 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 63468 64204 + orf19.5669 63468 64204 1 63468 64204 63561 64121 orf19.13114|IPF21546.1|IPF11301.1|Contig4-3054_0003|orf6.6909|CA4377|CaO19.13114|YET1|CaO19.5669|IPF11301 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 64117 66795 - orf19.5671 64117 66795 1 66795 64117 66706 64271 orf19.13116|IPF21511.1|IPF11299.2|Contig4-3054_0001|orf6.6911|CA4378|CaO19.5671|CaO19.13116|IPF11299 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 67702 71836 - orf19.5673 67702 71836 1 71836 67702 71749 69506 OPT7 orf19.13118|IPF21514.1|IPF12736.2|Contig4-2948_0004|orf6.6913|OPT3|CA4380|CaO19.5673|CaO19.13118|IPF12736 Putative oligopeptide transporter; possibly transports GSH and related compounds; induced upon biofilm formation; Hog1p-induced; expression of OPT6, -7, or -8 does not suppress defect of mutant lacking Opt1p, -2p, or -3p; fungal-specific [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 67942 69437 + orf19.5672 67942 69437 1 67942 69437 67995 69437 MEP2 orf19.13117|IPF21529.1|IPF12738.2|Contig4-2948_0002|orf6.6912|CA4379|CaO19.13117|CaO19.5672 Ammonium permease and regulator of nitrogen starvation-induced filamentation; 11 predicted transmembrane regions; in low nitrogen cytoplasmic C-terminus activates Ras/cAMP and MAPK signal transduction pathways to induce filamentation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chr4 69775 70013 + ntar_704 69775 70013 1 69775 70013 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 70269 70466 + ntar_705 70269 70466 1 70269 70466 70269 70457 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 71274 71555 + ntar_706 71274 71555 1 71274 71555 71301 71462 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 72795 73547 - orf19.5674 72795 73547 1 73547 72795 73547 72795 PGA10 orf19.13119|RBT51|RBT8|IPF21543.1|IPF20169.1|Contig4-2948_0005|orf6.6914|CA4381|CRW2|CaO19.5674|CaO19.13119|IPF20169 Plasma membrane protein involved in heme-iron utilization; allows utilization of hemin and hemoglobin as iron sources in host tissues; predicted GPI anchor; hypoxia, ketoconazole, ciclopirox, or hyphal-induced; upregulated by Rim101p at pH8 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr4 74088 77709 - orf19.5675 74088 77709 1 77709 74088 77579 74271 orf19.13120|IPF21563.1|IPF8576.2|Contig4-2948_0008|orf6.6915|CA4382|CaO19.5675|RIS1|CaO19.13120|IPF8576 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 78004 80344 - orf19.5676 78004 80344 1 80344 78004 80171 78360 orf19.13121|IPF8573.1|IPF27959.1|Contig4-2948_0010|orf6.6916|CA4383|CaO19.13121|CaO19.5676|IPF8573 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 80491 81318 + ntar_707 80491 81318 1 80491 81318 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 81343 83536 - ntar_708 81343 83536 1 83536 81343 83067 82807 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 81578 83551 + orf19.5677 81578 83551 1 81578 83551 81578 83551 DUR4 orf19.13122|IPF8570.2|IPF27956.1|Contig4-2948_0014|orf6.6917|CA4384|DUR34|CaO19.5677|CaO19.13122 [NOT TRANSCRIBED?] Putative urea permease; fungal-specific (no human or murine homolog) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 84045 85634 + orf19.5678 84045 85634 1 84045 85634 84045 85634 orf19.13123|IPF21548.1|IPF8567.3|orf6.6918 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 86247 89344 + orf19.4191.1 86247 89344 1 86247 89344 86317 89235 IPF23078.1|IPF7996.1|Contig4-2846_0013|CA1942|HCT5.3eoc ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 89227 90152 - orf19.4191 89227 90152 1 90152 89227 90017 89388 RLP24 orf19.11668|IPF23102.1|IPF7998.1|Contig4-2846_0001|orf6.3648|CA1941|CaO19.4191|CaO19.11668|IPF7998 Predicted ORF in Assemblies 19, 20 and 21; essential; S. cerevisiae ortholog is essential; heterozygous mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 90347 91149 + orf19.4190 90347 91149 1 90347 91149 90450 90923 orf19.11667|IPF23106.1|IPF7999.1|Contig4-2846_0003|orf6.3647|CA1940|PAM18|CaO19.11667|CaO19.4190|IPF7999 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 91409 92485 - orf19.4189 91409 92485 1 92485 91409 92485 91409 orf19.11666|IPF23094.1|IPF8000.2|Contig4-2846_0004|orf6.3646|CA1939|CaO19.4189|CaO19.11666|IPF8000 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr4 93587 96843 - orf19.4188 93587 96843 1 96843 93587 96782 93729 NMD5 orf19.11665|IPF23113.1|IPF8002.2|Contig4-2846_0007|orf6.3645|CA1938|CaO19.4188|CaO19.11665 Protein not essential for viability; similar to S. cerevisiae Nmd5p, which is involved in protein-nucleus import; downregulated during core stress response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 97156 97327 - ntar_709 97156 97327 1 97327 97156 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 97328 97398 - tg(ccc)1 97328 97398 1 97398 97328 tG(CCC)1.2 tRNA-Gly predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 97488 98929 - orf19.4187 97488 98929 1 98929 97488 98893 97574 orf19.11664|IPF23092.1|IPF8006.2|Contig4-2846_0008|orf6.3644|CA1937|MMM1|CaO19.4187|CaO19.11664 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 99068 100587 - orf19.4186 99068 100587 1 100587 99068 100504 99131 PCT1 orf19.11663|IPF23090.1|IPF8007.2|Contig4-2846_0009|orf6.3643|CA1936|CaO19.4186|CaO19.11663 Putative choline-phosphate cytidylyl transferase, antigenic during human oral infection [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 100703 101721 + orf19.4185 100703 101721 1 100703 101721 100986 101441 orf19.11662|IPF23105.1|IPF19936.1|Contig4-2846_0011|orf6.3642|CA1935|CaO19.11662|CaO19.4185|IPF19936 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 101440 103837 - orf19.4184 101440 103837 1 103837 101440 103606 101597 orf19.11660|IPF11891.2|IPF28501.1|Contig4-2846_0012|orf6.3641|orf6.6078|CA3734|YAP180|CaO19.4184|YAP1802|CA1934|YAP1802.3eoc|IPF8015.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 102138 102377 + ntar_710 102138 102377 1 102138 102377 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 104048 104264 + ntar_711 104048 104264 1 104048 104264 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 104302 107110 - orf19.4183 104302 107110 1 107110 104302 107085 104422 MUC1 orf19.11659|IPF11897.2|IPF28500.1|Contig4-2567_0006|Contig4-2567_0007|Contig4-2567_0008|orf6.6077|CA3733|CaO19.4183|IPF11897 Protein not essential for viability; similar to S. cerevisiae Muc1p, which is a cell surface glycoprotein involved in filamentous growth; decreased transcription is observed upon benomyl treatment [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 107237 108479 + orf19.4182 107237 108479 2 107237|107490 107422|108479 107346 108402 orf19.11658|IPF23096.1|IPF11898.2|Contig4-2567_0004|orf6.6076|CA3732|CaO19.11658|CaO19.4182|IPF11898 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 108327 108972 - orf19.4181 108327 108972 1 108972 108327 108930 108421 SPC2 orf19.11657|IPF23103.1|IPF11899.1|Contig4-2567_0003|orf6.6075|CA3731|CaO19.4181|CaO19.11657 Transcription is induced upon filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 109114 110078 - orf19.4180 109114 110078 1 110078 109114 110013 109399 orf19.11656|IPF23101.1|IPF11900.1|Contig4-2567_0002|orf6.6074|CA3730|SEC72|CaO19.11656|CaO19.4180|IPF11900 Protein described as component of ER protein-translocation complex; regulated by Gcn4p; repressed in response to amino acid starvation (3-aminotriazole treatment) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 110388 110918 + orf19.4179 110388 110918 1 110388 110918 110388 110918 orf19.11655|IPF23104.1|IPF11901.2|Contig4-2567_0001|orf6.6073|CA3729|CaO19.11655|CaO19.4179|IPF11901 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr4 111241 112555 + orf19.4177 111241 112555 1 111241 112555 111285 112454 HIS5 orf19.11653|IPF23080.1|IPF23095.1|IPF11902.2|IPF6173.2|Contig4-2228_0011|orf6.6071|CA3727|HIS5.3f|orf19.4177.1 Predicted ORF in Assemblies 19, 20 and 21; Gcn4p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 112656 113556 + orf19.4176 112656 113556 1 112656 113556 112699 113439 orf19.11652|IPF23099.1|IPF6175.1|Contig4-2228_0001|orf6.6070|CA3726|MRPS17|CaO19.4176|CaO19.11652|IPF6175 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 113645 115913 + orf19.4175 113645 115913 1 113645 115913 113653 115878 TOK1 orf19.11651|IPF23079.1|IPF6179.2|Contig4-2228_0004|Contig4-2228_0005|orf6.6069|CA3725|CaO19.11651|CaO19.4175|TOK1.3f|TOK1.3 Outwardly rectifying, noisily gated potassium channel; modulates sensitivity to human salivary histatin (Hst5); very similar to S. cerevisiae Tok1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 116142 117668 + orf19.4174 116142 117668 1 116142 117668 116226 117587 orf19.11650|IPF23089.1|IPF6181.2|Contig4-2228_0008|orf6.6068|CA3724|CaO19.4174|CaO19.11650|IPF6181 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 117507 119173 - orf19.4173 117507 119173 1 119173 117507 119173 117584 orf19.11649|IPF16546.1|IPF23088.1|IPF6183.2|Contig4-2948_0015|orf6.814|orf6.6067|CA3723|orf19.1174|CaO19.11649|DPH2|CaO19.4173 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr4 119374 120573 - orf19.4172 119374 120573 1 120573 119374 120395 119430 orf19.11648|IPF23097.1|IPF6184.2|Contig4-2878_0001|Contig4-2878_0002|orf6.6066|CA3722|CaO19.4172|PHO133|CaO19.11648|PHO13 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 120890 123056 + orf19.4171 120890 123056 1 120890 123056 121074 123011 orf19.11647|IPF6186.1|IPF17597.2|Contig4-2878_0005|orf6.101|orf6.6065|CA3721|CaO19.4171|IPF6186 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 123577 124577 - ntar_712 123577 124577 1 124577 123577 123946 123812 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 124050 124874 + orf19.4170 124050 124874 1 124050 124874 124050 124874 orf19.11646|IPF6188.1|IPF28505.1|Contig4-2878_0006|orf6.6064|CA3720|CIS309|CaO19.11646|CaO19.4170|IFL3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 124697 124943 - ntar_713 124697 124943 1 124943 124697 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 125066 125668 - orf19.4169 125066 125668 1 125668 125066 125653 125258 orf19.11645|IPF6190.1|IPF17810.2|Contig4-2878_0008|orf6.123|orf6.6063|CaO19.4169 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 125881 126624 + orf19.4168 125881 126624 1 125881 126624 126015 126518 orf19.11644|IPF6191.1|IPF17808.1|Contig4-2878_0009|orf6.124|orf6.6062|CA3718|POP7|CaO19.4168 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 126471 127231 - orf19.4167 126471 127231 1 127231 126471 127113 126574 orf19.11643|IPF6192.2|IPF17807.3|orf6.125|orf6.6061|CA3717|CaO19.4167|IPF6192 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 129892 130109 - ntar_714 129892 130109 1 130109 129892 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 130260 130792 - ntar_715 130260 130792 1 130792 130260 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 131821 133911 + orf19.4166 131821 133911 1 131821 133911 131943 133832 ZCF21|orf19.11642|IPF6203.2|IPF28502.1|Contig4-2878_0017|orf6.6060|CA3716|CaO19.11642|CaO19.4166|IPF6203 Predicted zinc-finger protein of unknown function [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 133915 135216 - orf19.4164 133915 135216 1 135216 133915 135159 134425 orf19.11640|IPF23100.1|IPF6205.2|Contig4-2878_0020|orf6.6058|CA3715|CaO19.4164|CaO19.11640|IPF6205 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 134988 135396 + ntar_716 134988 135396 1 134988 135396 135197 135352 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 135451 139215 - orf19.4163 135451 139215 1 139215 135451 138778 135560 orf19.11639|IPF16223.2|IPF28511.1|orf6.6057|CA3714|CaO19.4163|CaO19.11639|IPF16223 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 140461 142838 - orf19.4162 140461 142838 1 142838 140461 142783 140630 MLH1 orf19.11638|IPF23081.1|IPF15970.2|Contig4-2312_0003|orf6.2626|CA1229|CaO19.4162|CaO19.11638 Predicted ORF in Assemblies 19, 20 and 21; cell-cycle regulated periodic mRNA expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr4 142960 144186 + orf19.4161 142960 144186 1 142960 144186 142987 144102 orf19.11637|IPF18734.2|IPF16081.2|Contig4-2312_0002|orf6.2625|CA1228|CaO19.11637|QRI2|CaO19.4161|IPF16081 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 144077 145585 - orf19.4160 144077 145585 1 145585 144077 145508 144156 orf19.11636|IPF23091.1|IPF16082.2|Contig4-2312_0001|orf6.2624|CA1227|QRI7|CaO19.4160|CaO19.11636|IPF16082 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 145984 147501 + orf19.4159 145984 147501 1 145984 147501 146332 147432 orf19.11635|IPF23093.1|IPF15660.2|Contig4-1990_0003|orf6.2623|CA1226|CaO19.4159|CaO19.11635|IPF15660 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 147407 147916 - ntar_717 147407 147916 1 147916 147407 147833 147642 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 147972 149128 + orf19.4157 147972 149128 1 147972 149128 148176 149048 SPS20 orf19.11633|IPF23098.1|IPF15661.1|Contig4-1990_0001|orf6.2621|CA1225|CaO19.11633|SPS199|CaO19.4157 Predicted ORF in Assemblies 19, 20 and 21; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 148616 148800 - ntar_718 148616 148800 1 148800 148616 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 148995 149144 - ntar_719 148995 149144 1 149144 148995 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 149310 152293 + orf19.4711 149310 152293 1 149310 152293 149466 152171 orf19.12182|orf19.11632|IPF23108.1|IPF15662.1|IPF22557.1|IPF4435.2|Contig4-2960_0021|orf6.2620|orf6.3510|CA1224|CA1839|orf19.4156|CaO19.4711|CaO19.12182|IPF4435 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr4 152472 154610 - orf19.4707 152472 154610 1 154610 152472 154610 152472 orf19.12178|orf6.3514|IPF22562.1|IPF4440.2|Contig4-2960_0019|CA1840|ASM1|CaO19.4707|CaO19.12178|IFP3 Putative secreted acid sphingomyelin phosphodiesterase; possible Kex2p substrate [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 155500 156489 - orf19.4706 155500 156489 1 156489 155500 156363 155866 orf19.12177|IPF4443.2|IPF19339.2|Contig4-2960_0017|orf6.328|orf6.3515|CA0051|CaO19.4706|IPF4443 Predicted ORF in Assemblies 19, 20 and 21; greater mRNA abundance observed in a cyr1 or ras1 homozygous null mutant than in wild type; fluconazole-induced; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 157071 157141 + tg(ucc)2 157071 157141 1 157071 157141 tG(UCC)2.2 tRNA-Gly predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 157223 159020 + orf19.4705 157223 159020 1 157223 159020 157274 158917 orf19.12176|IPF19340.2|IPF4444.2|Contig4-2960_0015|orf6.327|orf6.3516|CCA1|CaO19.4705|CA1841 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr4 159223 163988 + orf19.4704 159223 163988 1 159223 163988 159251 163906 ARO1 orf19.12175|IPF22652.1|IPF4446.2|Contig4-2960_0014|orf6.1758|orf6.3517|CA1842|CaO19.4704 Putative pentafunctional arom enzyme; fungal-specific (no human or murine homolog); Gcn2p-, Gcn4p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 163890 164170 - tg(gcc)5 163890 164170 1 164170 163890 tG(GCC)5.2 tRNA-Gly predicted by tRNAscan-SE [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr4 164295 164491 - ntar_720 164295 164491 1 164491 164295 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 164372 164612 + ntar_721 164372 164612 1 164372 164612 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 165066 166832 - orf19.4703 165066 166832 1 166832 165066 166832 165126 IPF14519.1|IPF16379.2|Contig4-2960_0009|Contig4-2960_0010|orf6.3518|orf6.1755|CA6288|CaO19.4703|IPF14519.3f Predicted ORF in Assemblies 19, 20 and 21; has similarity to mutator-like element (MULE) transposase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 166705 167702 - orf19.4702 166705 167702 1 167702 166705 167607 166705 orf19.12172|IPF14519.1|IPF16377.2|Contig4-2960_0008|orf6.3519|orf6.1755|CA0683|CaO19.4702|IPF14519.5f|IPF14519 Predicted ORF in Assemblies 19, 20 and 21; expression regulated during planktonic growth; similarity to mutator-like element (MULE) transposase; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 168228 168298 + tg(gcc)4 168228 168298 1 168228 168298 tG(GCC)4.2 tRNA-Gly predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 168363 169394 + orf19.4701 168363 169394 1 168363 169394 168396 169394 orf19.12171|IPF14514.1|IPF16375.2|orf6.1754|orf6.3520|CA0682|CaO19.4701|IPF14514 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=C scenario_last_exon=C] Ca21chr4 169298 171727 - orf19.4699 169298 171727 1 171727 169298 171505 169448 orf19.12169|orf19.12170|orf6.1752|IPF14511.2|IPF17016.3|Contig4-2960_0001|Contig4-2960_0003|Contig4-2960_0004|orf6.1686|orf6.1753|orf6.3521|CA6287|CA0680|orf19.4700|IPF14511.5f|IPF14511.3f|CA0681|IPF14513.2 Putative phospholipase of patatin family; similar to S. cerevisiae Ymr313p; predicted Kex2p substrate [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr4 172842 173144 + ntar_722 172842 173144 1 172842 173144 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 173405 173653 + ntar_723 173405 173653 1 173405 173653 173516 173653 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 173881 176054 + orf19.4698 173881 176054 1 173881 176054 174443 175708 PTC8 orf19.12168|IPF22595.1|IPF15977.2|orf6.1685|CA0641|CaO19.12168|DHP99|CaO19.4698|IPF15977 Predicted type 2C protein phosphatase, serine/threonine-specific; required for hyphal growth; induced under stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 175941 191174 - orf19.4697 175941 191174 1 191174 175941 191174 176061 MDN1 orf19.12167|IPF22610.1|IPF11189.3|Contig4-1657_0002|Contig4-1657_0003|Contig4-2496_0003|orf6.1058|orf6.1684|orf6.1709|orf6.759|CA0283|CaO19.4697|IPF18034|IPF18034.2 Protein induced during the mating process [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr4 191550 191811 + ntar_724 191550 191811 1 191550 191811 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 192187 192792 - orf19.4691 192187 192792 1 192792 192187 192792 192187 orf19.12160|IPF17417.2|IPF11193.2|Contig4-2496_0004|orf6.1057|orf6.1708|CA0282|CaO19.4691|IPF17417 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 194291 194987 + ntar_725 194291 194987 1 194291 194987 194291 194584 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 195209 196942 + orf19.4690 195209 196942 1 195209 196942 195209 196942 orf19.12159|IPF17437.2|IPF14122.2|Contig4-2733_0001|orf6.1056|orf6.1770|orf6.460|CA0087|SMF11|SMF12|CaO19.4690 Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide in yhb1 mutant [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr4 197042 197980 - orf19.4689 197042 197980 1 197980 197042 197792 197148 PGA57 orf19.12158|IPF14121.2|IPF19267.2|Contig4-2733_0002|orf6.1769|orf6.461|CA6322|CaO19.4689 Putative GPI-anchored protein of unknown function [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 199318 200488 - orf19.4688 199318 200488 1 200488 199318 200233 199478 DAG7 orf19.12157|IPF14119.1|IPF28307.1|Contig4-2733_0007|orf6.1768|CA0689|CaO19.4688|CaO19.12157|IPF14119 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to toxic ergosterol analog; a-specific transcription; alpha-factor induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 201618 201936 - ntar_726 201618 201936 1 201936 201618 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 202154 206417 - orf19.4686 202154 206417 1 206417 202154 206038 202436 orf19.12155|IPF18902.2|IPF10555.3|Contig4-2733_0012|orf6.1766|orf6.5450|CA3238|CaO19.4686|IPF10555|CA0688|IPF10555.3eoc|IPF18902.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 206684 207114 + orf19.4685 206684 207114 1 206684 207114 206797 207114 orf19.12154|IPF22669.1|IPF28327.1|Contig4-2733_0016|orf6.5451|CaO19.4685|CaO19.12154 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr4 208041 208692 - orf19.4684.2 208041 208692 1 208692 208041 208643 208485 RPL40B IPF22579.1|IPF10558.1|CA3239|IPF10558 Protein with similarity to the ribosomal protein portion of S. cerevisiae Rpl40Bp; shows colony morphology-related gene regulation by Ssn6p; transcription is positively regulated by Tbf1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 209052 214726 + orf19.4683 209052 214726 1 209052 214726 209114 214612 MLP1 orf19.12152|IPF22637.1|IPF10559.2|Contig4-1629_0001|orf6.5453|orf6.68|CA3240|CaO19.4683|IPF10559 Protein similar to S. cerevisiae Mlp1p, which is a myosin-like protein [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 217149 218987 + orf19.4682 217149 218987 1 217149 218987 217149 218987 HGT17 orf19.12151|IPF22574.1|IPF7493.1|Contig4-2949_0011|orf6.5454|CA3241|QUP3|CaO19.4682|CaO19.12151|IPF7493 Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; induced at low (0.2%, compared to 2%) glucose in rich media [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr4 219412 222553 + orf19.4681 219412 222553 1 219412 222553 219462 222368 RAT1 orf19.12150|IPF22542.1|IPF7491.1|Contig4-2949_0009|Contig4-2949_0010|orf6.5455|CA3242|CaO19.12150|CaO19.4681 5'-->3' exoribonuclease; similar to S. cerevisiae nuclear exoribonuclease Rat1p; suppresses S. cerevisiae kem1 mutant slow growth, mating defect, and haploid invasive growth defect [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 222300 223595 - orf19.4680 222300 223595 1 223595 222300 223559 222414 orf19.12149|IPF22604.1|IPF7489.2|Contig4-2949_0008|orf6.5456|CA3243|DGK1|CaO19.12149|CaO19.4680|IPF7489 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to toxic ergosterol analog [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 223078 223380 + ntar_727 223078 223380 1 223078 223380 223078 223245 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 223764 225707 - orf19.4679 223764 225707 1 225707 223764 225566 223860 AGP2 orf19.12148|IPF17868.3|IPF7487.2|Contig4-2949_0007|orf6.5457|CA3244|CaO19.12148|CaO19.4679 Protein described as an amino acid permease; hyphal downregulated; regulated upon white-opaque switching; induced in core caspofungin response, during cell wall regeneration, or by flucytosine; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 227792 227863 + td(guc)6 227792 227863 1 227792 227863 tD(GUC)6.2 tRNA-Asp predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 227920 229031 - orf19.4678 227920 229031 1 229031 227920 229004 228003 orf19.12147|IPF22612.1|IPF19980.1|Contig4-2949_0004|orf6.5458|CA3245|CaO19.4678|IPF19980 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 229188 230003 - orf19.4677 229188 230003 1 230003 229188 229969 229259 IPF22661.1|IPF15830.2|Contig4-2949_0003|orf6.5459|CA3246|CaO19.4677|IPF15830 Putative protein of unknown function, transcription is upregulated in clinical isolates from HIV+ patients with oral candidiasis; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 230424 231137 - orf19.4676 230424 231137 1 231137 230424 231137 230595 orf19.12146|IPF22636.1|IPF15832.1|Contig4-2949_0002|orf6.5460|CA3247|CaO19.12146|CaO19.4676|IPF15832 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr4 231124 233029 + orf19.4675 231124 233029 1 231124 233029 231171 232955 orf19.12145|IPF22566.1|IPF15834.1|orf6.5461|CA3248|CaO19.12145|CaO19.4675|IPF15834 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 233498 234043 + orf19.4674.1 233498 234043 1 233498 234043 233670 233900 CRD2 orf19.12144.1 Metallothionein; role in adaptation to growth with high concentration of copper ions; basal transcription is cadmium-repressed; regulated by Ssn6p; complements copper sensitivity of an S. cerevisiae cup1 null mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 234413 236764 - orf19.4673 234413 236764 1 236764 234413 236764 234413 BMT9 orf19.12143|orf19.12144|IPF22601.1|IPF7421.2|Contig4-2135_0001|Contig4-2135_0002|orf6.4062|orf6.4063|CA2242|CA2241|orf19.4674|IFQ1.5f [NOT TRANSCRIBED?] Putative beta-mannosyltransferase, member of a 9-gene family that includes characterized genes BMT1, BMT2, BMT3, and BMT4 with roles in beta-1,2-mannosylation of cell wall phosphopeptidomannan; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 240313 240615 + orf19.4672 240313 240615 1 240313 240615 240313 240615 orf19.12142|IPF22700.1|IPF28345.1|orf6.4064|CaO19.12142|CaO19.4672 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 241333 243946 + orf19.4670 241333 243946 1 241333 243946 241405 243870 CAS5 orf19.12140|IPF22550.1|IPF7414.1|Contig4-2599_0003|orf6.4066|CA2243|CaO19.12140|CaO19.4670|IPF7414 Putative zinc finger transcription factor; cell wall damage response; required for wild-type transcriptional response to caspofungin; mutant caspofungin hypersensitive; downregulated in core stress response; avirulent, reduced CFU in mice [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 243959 245473 - orf19.4669 243959 245473 1 245473 243959 245382 244153 AAT22 orf19.12139|IPF18504.2|IPF7410.2|Contig4-2599_0006|orf6.4067|CA2244|CaO19.4669|CaO19.12139 Protein not essential for viability; similar to S. cerevisiae Aat2p, which is an aspartate aminotransferase involved in nitrogen metabolism; clade-associated gene expression; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 245701 245782 - ts(uga)3 245701 245782 1 245782 245701 tS(UGA)3.2 tRNA-Ser predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 246065 248309 - orf19.4668 246065 248309 1 248309 246065 248280 246127 orf19.12138|IPF7409|IPF22559.1|IPF7409.2|Contig4-2599_0007|Contig4-2599_0010|orf6.4068|CA2245|CaO19.4668|CaO19.12138 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr4 248397 249499 - orf19.4666 248397 249499 1 249499 248397 249238 248828 orf19.12136|IPF22655.1|IPF7405.2|Contig4-2599_0012|Contig4-2819_0014|orf6.4070|CA2246|CaO19.4666|CaO19.12136|IPF7405 Predicted ORF in Assemblies 19, 20 and 21; hyphal-induced expression, regulated by Cyr1p, Ras1p, Efg1p; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 249746 250710 - orf19.4665 249746 250710 1 250710 249746 250645 250043 orf19.12135|IPF7404.1|IPF18428.2|Contig4-2819_0013|orf6.4071|orf6.4716|CA2247|CaO19.4665|IPF7404 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 250828 251822 + orf19.4664 250828 251822 1 250828 251822 250884 251564 NAT4 orf19.12134|IPF22668.1|IPF7403.2|Contig4-2819_0011|orf6.4072|orf6.4715|CA2710|CaO19.4664|IPF7403 Putative histone acetyltransferase, involved in regulation of white-opaque switching; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr4 252331 252594 - ntar_728 252331 252594 1 252594 252331 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 252995 255236 + orf19.4662 252995 255236 1 252995 255236 253048 254883 RLM1 orf19.12132|IPF22573.1|IPF4828.2|Contig4-2819_0007|orf6.4713|CA2709|CaO19.12132|CaO19.4662|IPF4828 Putative transcription factor; required for wild-type resistance to cell wall perturbation, caspofungin treatment; regulates caspofungin induction of PGA13 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 253235 254968 - ntar_729 253235 254968 1 254968 253235 254023 253757 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 255454 257242 + orf19.4660 255454 257242 2 255454|256105 255679|257242 255674 256809 RPS6A orf19.12130|orf6.4711|IPF22630.1|IPF11001.1|RPS6B|Contig4-2819_0006|CA2708 Predicted ribosomal protein; similar to ribosomal protein S10; localizes to cell surface of yeast-form cells, but not hyphal cells; genes encoding cytoplasmic ribosomal subunits are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 257035 258394 - orf19.4659 257035 258394 1 258394 257035 258350 257073 orf19.12129|IPF22593.1|IPF11003.2|Contig4-2819_0005|orf6.4710|CA2707|SAP114|CaO19.12129|CaO19.4659|IPF11003 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 258694 261545 + orf19.4658 258694 261545 1 258694 261545 258971 261361 orf19.12128|IPF11006|IPF22549.1|IPF11006.2|Contig4-2819_0003|orf6.4709|CA2706|CaO19.12128|HYZ99|CaO19.4658 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 260365 261118 - ntar_730 260365 261118 1 261118 260365 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 261219 261473 - ntar_731 261219 261473 1 261473 261219 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 261786 262520 - ntar_732 261786 262520 1 262520 261786 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 263243 265732 + orf19.4657 263243 265732 1 263243 265732 263911 265413 orf19.12127|IPF22586.1|IPF12196.2|orf6.4708|CA2705|CaO19.4657|NEM1|CaO19.12127 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 266084 268324 + orf19.4656 266084 268324 1 266084 268324 266125 268023 orf19.12126|IPF22567.1|IPF12195.2|Contig4-2565_0001|Contig4-2565_0002|orf6.4707|CA2704|CaO19.12126|CaO19.4656|IPF12195 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr4 267917 270892 - orf19.4655 267917 270892 1 270892 267917 270892 268055 OPT6 orf19.12125|IPF22541.1|IPF12193.2|Contig4-2565_0003|orf6.4706|CA2703|OPT26|CaO19.12125|CaO19.4655|IPF12193 Putative oligopeptide transporter; fungal-specific (no human or murine homolog); expression of OPT6, OPT7, or OPT8 does not suppress defect of mutant lacking Opt1p, Opt2p, and Opt3p; alleles are nonidentical [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr4 272024 272451 + orf19.4654 272024 272451 1 272024 272451 272098 272427 orf19.12124|IPF22682.1|IPF12190.2|Contig4-2565_0005|orf6.4705|CaO19.4654|CaO19.12124 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 273193 273846 + orf19.4653 273193 273846 1 273193 273846 273296 273625 orf19.12123|orf4.4704|IPF22681.1|IPF12189.1|Contig4-2565_0007|orf6.4704|CaO19.4653|CaO19.12123 Transcriptionally regulated by iron; expression greater in low iron; similar to GPI-linked cell-wall proteins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 274725 275036 + orf19.4652 274725 275036 1 274725 275036 274725 275036 orf19.12122|IPF12187.2|IPF28322.1|Contig4-2565_0008|orf6.4703|orf6.77|CaO19.4652 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 275958 276751 - ntar_733 275958 276751 1 276751 275958 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 277105 277451 + ntar_734 277105 277451 1 277105 277451 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 278127 278871 + orf19.4651 278127 278871 1 278127 278871 278273 278692 PGA53 orf19.12120|IPF15581.2|IPF9303.2|Contig4-2275_0007|orf6.305|orf6.3348|CA1720|CaO19.4651|IPF15581 GPI-anchored cell surface protein of unknown function; greater mRNA abundance observed in a cyr1 homozygous null mutant than in wild type [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 279638 280179 - ntar_735 279638 280179 1 280179 279638 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 280531 281617 + orf19.4650 280531 281617 1 280531 281617 280567 281478 ILV6 orf19.12119|IPF9306.1|IPF15583.2|Contig4-2275_0003|orf6.304|orf6.3347|CA1719|CaO19.4650 Putative regulatory subunit of acetolacetate synthase ; fungal-specific (no human or murine homolog); alkaline upregulated; regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 281864 282019 + ntar_736 281864 282019 1 281864 282019 281864 281989 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 282266 282757 + ntar_737 282266 282757 1 282266 282757 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 282365 282635 - ntar_738 282365 282635 1 282635 282365 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 283046 287111 + orf19.4649 283046 287111 1 283046 287111 283245 286835 ZCF27|orf19.12118|IPF22676.1|IPF9312.1|Contig4-3006_0019|orf6.3346|CA1718|CaO19.12118|CaO19.4649|IPF9312 Putative transcription factor with zinc cluster DNA-binding motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 287660 288817 + orf19.4647 287660 288817 2 287660|287925 287805|288817 287709 288817 HAP3 orf19.12116|orf6.3344|IPF22615.1|IPF9315.2|HAP32|Contig4-1826_0002|CA1717|CaO19.4647|CaO19.12116|IPF9315 Protein described as similar to CCAAT-binding transcription factor that regulates respiration; expression greater in low iron; transcription is opaque specific, alkaline upregulated, ciclopirox olamine induced [label_first_exon=CGDmod label_last_exon=CGD orf_changed=false scenario_first_exon=A scenario_last_exon=E] Ca21chr4 287955 288922 - ntar_739 287955 288922 1 288922 287955 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 290969 291229 - ntar_740 290969 291229 1 291229 290969 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 291002 291790 + orf19.4646 291002 291790 1 291002 291790 291302 291739 UEC1 IPF22672.1|IPF13603.2|Contig4-2362_0001|orf6.1489|CaO19.4646 Protein required for damage to oral epithelial cells and for normal hyphal growth and stress resistance; transcription induced on contact with vascular endothelial cells; not highly conserved [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 291830 294334 + orf19.4645 291830 294334 1 291830 294334 292116 294014 BEM1 orf19.12115|IPF18620.2|IPF13602.2|Contig4-2362_0002|orf6.1490|orf6.3343|CA0514|CaO19.4645 Protein required for wild-type budding, hyphal growth, and virulence in a mouse systemic infection; suppresses pseudohyphal and filamentous growth defects of various S. cerevisiae mutants and heat sensitivity of S. cerevisiae cdc24-4 mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 294807 302087 + orf19.4643 294807 302087 1 294807 302087 294807 301958 orf19.12113|IPF19720.2|IPF28308.1|Contig4-2362_0003|Contig4-2596_0007|Contig4-2596_0008|orf6.1491|orf6.2365|CA1061|CaO19.4643|IPF19720|IPF19720.3eoc|IPF19720.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr4 301983 303440 - orf19.4642 301983 303440 1 303440 301983 303347 302091 orf19.12112|IPF22602.1|IPF14165.2|Contig4-2596_0004|orf6.2366|CA1062|CaO19.4642|CaO19.12112|IPF14165 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 303578 305091 + orf19.4641 303578 305091 1 303578 305091 303654 305009 NMT1 orf19.12111|NMT|IPF22592.1|IPF15592.2|Contig4-2596_0003|orf6.2367|CA1063|CaO19.4641|CaO19.12111 Myristoyl-CoA:protein N-myristoyltransferase; attaches the fatty acid myristate to a small number of proteins at an N-terminal Gly; essential; antifungal drug target; functional homolog of S. cerevisiae Nmt1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 305281 307258 + orf19.4640 305281 307258 1 305281 307258 305343 307184 PWP1 orf19.12110|IPF15595.2|IPF28303.1|Contig4-2596_0001|orf6.2368|CA1064 Predicted ORF in Assemblies 19, 20 and 21; downregulated in core stress response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 307164 308101 - orf19.4639 307164 308101 1 308101 307164 307948 307274 orf19.12108|IPF9002.2|IPF28309.1|Contig4-2825_0001|orf6.2370|CA1065|CaO19.4639|IPF9002 Predicted ORF in Assemblies 19, 20 and 21; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 308177 309718 + orf19.4637 308177 309718 1 308177 309718 308265 309626 orf19.12107|IPF9001.2|IPF28305.1|Contig4-2825_0004|Contig4-2825_0005|orf6.2371|CA1066|orf19.4638 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 309483 309905 - orf19.4636 309483 309905 1 309905 309483 309905 309483 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 309965 312876 + orf19.4635 309965 312876 1 309965 312876 310023 312647 NIP1 orf19.12105|IPF22546.1|IPF8998.2|Contig4-2825_0008|orf6.1839|orf6.2373|CA0733|CaO19.4635 Putative translation initiation factor; mutation confers hypersensitivity to roridin A and verrucarin A; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 313001 314293 + orf19.4634 313001 314293 1 313001 314293 313048 314235 orf19.12104|IPF22600.1|IPF8996.2|Contig4-2825_0012|orf6.1840|CA0734|CaO19.4634|CaO19.12104|IPF8996 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 313938 314232 - ntar_741 313938 314232 1 314232 313938 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 314375 315599 + orf19.4633 314375 315599 1 314375 315599 314590 315396 orf19.12103|IPF22622.1|IPF8995.1|Contig4-2825_0014|orf6.1841|CA0735|CaO19.12103|CaO19.4633|IPF8995 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 315421 316861 - orf19.4632 315421 316861 2 316861|316287 316677|315421 316283 315765 RPL20B orf19.12102|IPF22642.1|IPF8994.2|Contig4-2825_0015|orf6.1842|CA0736|RPL20|CaO19.4632 Predicted ribosomal protein; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage; intron in 5'-UTR [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr4 317039 318349 - orf19.4631 317039 318349 1 318349 317039 318197 317232 ERG251 orf19.12101|IPF8993.1|IPF18887.2|Contig4-2825_0017|orf6.1843|orf6.2054|CA0875|ERG252|CaO19.4631 Predicted ORF in Assemblies 19, 20 and 21; ketoconazole-induced; amphotericin B, caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 319749 320120 + ntar_742 319749 320120 1 319749 320120 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 320142 321618 - orf19.4630 320142 321618 1 321618 320142 321528 320236 CPA1 orf19.12100|IPF11885.2|IPF18128.2|Contig4-2886_0008|orf6.2053|CA0874|CaO19.4630 Putative carbamoyl-phosphate synthase subunit; alkaline downregulated; transcription is upregulated in both intermediate and mature biofilms [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 321796 324833 - orf19.4629 321796 324833 1 324833 321796 324742 321845 orf19.12099|IPF9241.2|IPF18129.1|Contig4-2953_0001|Contig4-2953_0002|orf6.2052|orf6.7928|CA0873|BUL1|CaO19.4629 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 324936 325614 - ntar_1432 324936 325614 2 325614|325295 325524|324936 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 325876 327509 - ntar_1431 325876 327509 5 327509|327210|326931|326705|326464 327444|327206|326931|326705|325876 326398 326276 [label_first_exon=CGDmod label_last_exon=CGD orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr4 327655 329366 - orf19.4628 327655 329366 1 329366 327655 329218 327722 orf19.12098|IPF22582.1|IPF10155.2|Contig4-2945_0027|orf6.7927|CA5190|CaO19.4628|CaO19.12098|IPF10155 Putative protein of unknown function; heterozygous null mutant exhibits hypersensitivity to parnafungin and cordycepin in the C. albicans fitness test; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 327807 327941 + ntar_743 327807 327941 1 327807 327941 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 329418 332989 + orf19.4627 329418 332989 1 329418 332989 329559 332903 orf19.12097|IPF22689.1|IPF10158.2|Contig4-2945_0025|orf6.7926|CA5189|CaO19.12097|NUP120|CaO19.4627|IPF10158 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 332840 334323 - orf19.4626 332840 334323 1 334323 332840 334137 332956 orf19.12096|IPF22598.1|IPF10159.2|Contig4-2945_0024|orf6.7925|CA5188|TAP42|CaO19.12096|CaO19.4626 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 334378 335171 + orf19.4625 334378 335171 1 334378 335171 334560 334952 TOA2 orf19.12095|IPF22646.1|IPF10160.1|Contig4-2945_0022|orf6.7924|CA5187|CaO19.12095|CaO19.4625 Protein abundance is decreased in the CAI-4 strain background compared to the SC5314 strain background, and abundance is not affected by reintegration of URA3 in CAI-4; flucytosine induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 334971 336505 - orf19.4624 334971 336505 1 336505 334971 336398 335040 HRT2 orf19.12094|IPF22589.1|IPF10162.2|Contig4-2945_0020|Contig4-2945_0021|orf6.7923|CA5186|CaO19.12094|CaO19.4624 Protein described as having a role in Ty3 transposition; decreased expression in hyphae compared to yeast-form cells; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 337003 338783 - orf19.4623.3 337003 338783 2 338783|337610 338616|337003 337601 337323 NHP6A IPF22703.1|IPF10163.1|Contig4-2945_0015|CA5185 Protein described as nonhistone chromatin component; RNA abundance regulated by tyrosol and cell density; amphotericin B, caspofungin repressed; intron in 5'-UTR [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr4 339164 339691 + ntar_744 339164 339691 1 339164 339691 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 339267 339540 - ntar_745 339267 339540 1 339540 339267 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 339665 340995 - orf19.4623 339665 340995 1 340995 339665 340995 340567 orf19.12093|IPF22640.1|IPF11088.1|Contig4-2945_0011|orf6.7922|CaO19.12093|CaO19.4623 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 340967 342458 - orf19.4622 340967 342458 1 342458 340967 342124 340967 orf19.12092|IPF22603.1|IPF11090.1|Contig4-2945_0009|orf6.7921|CA6310|CA5183|CaO19.12092|CaO19.4622|IPF11090.5f|IPF11090.53f|IPF11090.exon1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 342628 345201 - orf19.4621 342628 345201 1 345201 342628 345094 342977 orf19.12091|IPF22563.1|IPF11093.2|Contig4-2945_0007|orf6.7920|CA5182|CaO19.12091|CaO19.4621|IPF11093 Predicted ORF in Assemblies 19, 20 and 21; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 345341 345916 + orf19.4620 345341 345916 1 345341 345916 345473 345802 orf19.12090|IPF22690.1|IPF11094.1|Contig4-2945_0006|orf6.7919|CA5181|MRS5|CaO19.4620|CaO19.12090|TIM12 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 345939 347338 - orf19.4618 345939 347338 1 347338 345939 347099 346020 FBA1 orf19.12088|ALF|IPF22611.1|IPF11096.2|Contig4-2945_0004|orf6.7917|CA5180|CaO19.12088|CaO19.4618 Putative fructose-bisphosphate aldolase; enzyme of glycolysis; antigenic in murine or human infection; regulated on yeast-hyphal switch; induced by Efg1p, Gcn4p, Hog1p, biofilm growth, or fluconazole; phagocytosis-repressed; fungal-specific [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 347870 348935 + orf19.4617 347870 348935 1 347870 348935 348197 348733 orf19.12087|IPF22631.1|IPF11098.1|Contig4-1340_0001|Contig4-2945_0002|orf6.7916|CA5179|MAK3|CaO19.4617 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 349109 350041 + orf19.4616 349109 350041 1 349109 350041 349157 349936 POL30 orf19.12086|IPF22623.1|IPF20027.1|orf6.7915|CA5178|CaO19.4616 Similar to proliferating cell nuclear antigen (PCNA); RNA abundance regulated by tyrosol and cell density; transcriptionally induced by interaction with macrophages; flucytosine induced; detected by mass spec in stationary phase culture [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 349974 351100 - orf19.4615 349974 351100 1 351100 349974 351044 350088 orf19.12085|IPF22618.1|IPF11101.2|Contig4-3081_0042|orf6.7914|CA5177|CaO19.4615|CaO19.12085|IPF11101 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 352032 355775 + orf19.4614 352032 355775 1 352032 355775 352173 355670 orf19.12084|IPF22683.1|IPF6045.2|orf6.7913|CA5176|ATG11|CaO19.4614|CaO19.12084|IPF6045 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr4 356462 357425 + orf19.4612 356462 357425 1 356462 357425 356583 357308 orf19.12082|IPF22625.1|IPF6041.2|Contig4-2931_0002|orf6.7911|CA5175|CaO19.12082|CaO19.4612|IPF6041 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 357908 358932 - orf19.4611 357908 358932 1 358932 357908 358932 357958 orf19.12081|IPF22617.1|IPF6040.1|Contig4-2931_0004|orf6.7910|CA5174|CaO19.12081|PRS4|CaO19.4611 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 359154 361012 - orf19.4610 359154 361012 1 361012 359154 360947 359154 orf19.12080|IPF22605.1|IPF6038.2|Contig4-2931_0006|orf6.7909|CA5172|CPS2|CaO19.4610|CaO19.12080|CPS2.5f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 361155 362007 - orf19.4609 361155 362007 1 362007 361155 361972 361241 orf19.12079|IPF22624.1|IPF6037.1|Contig4-2931_0007|orf6.7908|CA5171|CaO19.12079|CaO19.4609|IPF6037 Protein abundance is affected by URA3 expression in the CAI-4 strain background; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 362465 364384 - orf19.4608 362465 364384 2 364384|364010 364131|362465 364384 362465 PDC12 orf19.12078|IPF22693.1|IPF22581.1|IPF6034.1|IPF6036.1|Contig4-2931_0009|Contig4-2931_0010|orf6.7907|orf19.4607.2|CA5169|CA5170|PDC12.exon2 Putative pyruvate decarboxylase; fungal-specific (no human or murine homolog) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=J] Ca21chr4 364476 366149 - orf19.4607 364476 366149 1 366149 364476 366001 364697 orf19.12077|IPF19394.2|IPF6032.1|Contig4-2931_0011|orf6.198|orf6.7906|CA5168|CaO19.4607|IPF6032 Predicted ORF in Assemblies 19, 20 and 21; hyphal induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 366296 367807 - orf19.4606 366296 367807 1 367807 366296 367771 366473 ERG8 orf19.12076|IPF19393.2|IPF6030.2|Contig4-2931_0012|orf6.199|orf6.7905|CA5167|CaO19.4606 Putative phosphomevalonate kinase; enzyme of the mevalonate pathway of isoprenoid biosynthesis; transcription is regulated by Nrg1p; possible drug target, not conserved in H. sapiens [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 367924 369438 + orf19.4605 367924 369438 1 367924 369438 367992 369311 TYR1 orf19.12075|IPF22585.1|IPF6029.1|Contig4-2931_0013|Contig4-2931_0015|orf6.7904|CA5166|CaO19.12075|CaO19.4605 Putative prepephenate dehydrogenase; enzyme of tyrosine biosynthesis; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 369327 370286 - orf19.4603 369327 370286 1 370286 369327 369996 369439 ARL1 orf19.12073|IPF22634.1|IPF6027.1|Contig4-2931_0016|orf6.7902|CA5165|CaO19.12073|CaO19.4603 Predicted ORF in Assemblies 19, 20 and 21; mutation confers dose-dependent sensitivity to Brefeldin A [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 370434 371537 - orf19.4602 370434 371537 1 371537 370434 371508 370510 MDH1-1 orf19.12072|IPF22614.1|IPF6025.2|Contig4-2931_0017|orf6.7901|CA5164|MDH1|CaO19.4602|CaO19.12072 Predicted malate dehydrogenase; macrophage-induced protein [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 372251 374086 + orf19.4601 372251 374086 1 372251 374086 372364 373881 orf19.12071|IPF22583.1|IPF6022.2|Contig4-2931_0020|Contig4-3104_0073|orf6.7900|CA5163|TFC1|CaO19.4601|CaO19.12071 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 374003 374187 - ntar_746 374003 374187 1 374187 374003 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 374176 374892 + orf19.4600.1 374176 374892 1 374176 374892 374323 374601 IPF17436.2|IPF982.1|Contig4-1375_0002|Contig4-3104_0072|CA5162|IPF982 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 374594 375504 - orf19.4600 374594 375504 1 375504 374594 375425 374718 orf19.12069|IPF22627.1|IPF983.1|Contig4-3104_0071|orf6.7899|CA5161|CaO19.4600|CaO19.12069|IPF983 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 375478 375981 + ntar_747 375478 375981 1 375478 375981 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 377656 377892 + ntar_748 377656 377892 1 377656 377892 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 379579 381770 + orf19.4599 379579 381770 1 379579 381770 379777 381579 PHO89 orf19.12068|IPF22575.1|IPF988.1|Contig4-3104_0064|orf6.7898|CA5160|CaO19.12068|CaO19.4599 Putative phosphate permease; expression is regulated upon white-opaque switching; alkaline upregulated by Rim101p; induced upon biofilm formation; possibly adherence-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 381738 381873 - ntar_749 381738 381873 1 381873 381738 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 382192 383252 + orf19.4597 382192 383252 1 382192 383252 382277 383152 orf19.12066|IPF18131.2|IPF990.1|Contig4-3104_0063|orf6.7896|CAP2|CaO19.4597|CaO19.12066|CA5159 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 383193 384614 - orf19.4596 383193 384614 1 384614 383193 384532 383204 orf19.12065|IPF22594.1|IPF992.1|Contig4-3104_0062|orf6.7895|CA5158|CaO19.12065|CaO19.4596|IPF992 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 384798 384997 - ntar_750 384798 384997 1 384997 384798 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 385301 386734 + orf19.4595 385301 386734 1 385301 386734 385399 386712 orf19.12064|IPF22596.1|IPF993.1|Contig4-3104_0061|orf6.7894|CA5157|CaO19.12064|CaO19.4595|IPF993 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 386649 387540 - orf19.4594 386649 387540 1 387540 386649 387462 386785 orf19.12063|IPF22628.1|IPF994.1|Contig4-3104_0059|orf6.7893|CA5156|CaO19.4594|CLC1|CaO19.12063 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 387670 388284 + orf19.4593.1 387670 388284 1 387670 388284 387911 388147 IPF22544.1|IPF995.1|CA5155|IPF995 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 388178 392395 - orf19.4593 388178 392395 1 392395 388178 391839 388309 RGA2 orf19.12062|IPF22680.1|IPF1000.1|Contig4-3104_0056|orf6.7892|CA5154|CaO19.4593|CaO19.12062 Putative GTPase-activating protein (GAP) for Rho-type GTPase Cdc42p; involved in cell signaling pathways that control cell polarity; similar to S. cerevisiae Rga2p; induced upon low-level peroxide stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 394830 396636 - orf19.4592 394830 396636 1 396636 394830 396564 394930 HSX11 orf19.12061|IPF22578.1|IPF1003.2|Contig4-3104_0052|orf6.7891|CGT1|CA5153|CaO19.12061|CaO19.4592|IPF1003 UDP-glucose:ceramide glucosyltransferase (glucosylceramide synthase [GCS], EC 2.4.1.80); enzyme of sphingolipid metabolism [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 398001 400268 + orf19.4591 398001 400268 1 398001 400268 398208 400106 CAT2 orf19.12060|IPF22569.1|IPF1006.1|Contig4-3104_0049|orf6.7890|CTN2|CaO19.4591|CaO19.12060|CA5152 Major carnitine acetyl transferase localized in peroxisomes and mitochondria; involved in intracellular acetyl-CoA transport; transcriptionally induced in macrophage; farnesol-upregulated in biofilm; Hog1p-downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 405150 408485 + orf19.4590 405150 408485 1 405150 408485 405150 408485 RFX2 orf19.12059|IPF22684.1|IPF1009.1|Contig4-3104_0040|Contig4-3104_0041|Contig4-3104_0043|orf6.7889|CA5151|CaO19.4590|CaO19.12059|IPF1009 Transcriptional repressor; regulator of filamentation, response to DNA damage, adhesion, virulence in murine mucosal, systemic infections; RFX domain; regulated by Nrg1p, UV-induced; partially complements S. cerevisiae rfx1 mutant defects [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr4 408206 408762 - ntar_751 408206 408762 1 408762 408206 408439 408305 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 408902 410495 + orf19.4589 408902 410495 1 408902 410495 409049 410482 orf19.12058|IPF22588.1|IPF1011.1|Contig4-3104_0039|orf6.7888|CA5150|CaO19.12058|FMS1|CaO19.4589 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 410601 411776 + orf19.4587 410601 411776 1 410601 411776 410614 411702 HGH1 orf19.12056|IPF22606.1|IPF1013.1|Contig4-3104_0038|orf6.7886|CA5149|CaO19.12056|CaO19.4587 Transcription is regulated by Mig1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 411603 413765 - orf19.4585 411603 413765 1 413765 411603 413643 411817 TFG1 orf19.12054|IPF22571.1|IPF1015.1|Contig4-3104_0035|Contig4-3104_0037|orf6.7884|CA5148|CaO19.12054|CaO19.4585 Protein similar to S. cerevisiae Tfg1p, which is part of transcription factor TFIIF; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 413737 415945 + orf19.4584 413737 415945 1 413737 415945 414515 415885 PHO114 orf19.12053|IPF22591.1|IPF1016.1|PHO12|Contig4-3104_0034|orf6.7883|CA5147|CaO19.4584|CaO19.12053 Acid phosphatase, transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 416124 417232 + orf19.4583 416124 417232 1 416124 417232 416212 417141 orf19.12052|IPF22608.1|IPF1017.1|Contig4-3104_0033|orf6.7882|CA5146|CaO19.12052|YMC3|CaO19.4583|YMC2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 417030 418019 - orf19.4582 417030 418019 1 418019 417030 417943 417221 orf19.12051|IPF22629.1|IPF1018.1|Contig4-3104_0032|orf6.7881|CA5145|SKI6|CaO19.4582|CaO19.12051 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 418090 419416 - orf19.4581 418090 419416 1 419416 418090 419330 418134 orf19.12050|IPF22599.1|IPF1019.1|Contig4-3104_0030|orf6.7880|CA5144|CaO19.4581|CaO19.12050|IPF1019 Predicted ORF in Assemblies 19, 20 and 21; regulated by Tsa1p, Tsa1Bp under H2O2 stress conditions [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 419431 420274 + orf19.4580 419431 420274 1 419431 420274 419541 420074 orf19.12049|IPF22635.1|IPF1020.1|Contig4-3104_0027|orf6.7879|CA5143|CaO19.12049|CaO19.4580|IPF1020 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 420922 422257 + orf19.4579 420922 422257 1 420922 422257 421118 422044 orf19.12048|IPF22619.1|IPF1022.1|Contig4-3104_0026|orf6.7878|CA5142|CaO19.12048|CaO19.4579|IPF1022 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 422333 423255 + orf19.4578 422333 423255 1 422333 423255 422377 423132 CYT2 orf19.12047|orf6.7877|IPF22621.1|IPF1023.2|Contig4-3104_0025|CA5141|CaO19.12047|CaO19.4578 Protein described as cytochrome c1 heme lyase; transcription is regulated by Nrg1p; transcriptionally regulated by iron; expression greater in high iron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 423089 423579 - orf19.4577.3 423089 423579 1 423579 423089 423542 423267 IPF22647.1|IPF1024.1|Contig4-3104_0024|CA5140|TIM10 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 423744 427083 - orf19.4577 423744 427083 1 427083 423744 427083 423772 orf19.12046|IPF22688.1|IPF1027.1|Contig4-3104_0020|Contig4-3104_0022|orf6.7876|CA5139|CaO19.12046|CaO19.4577|IPF1027 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr4 427289 430040 - orf19.4575 427289 430040 3 430040|427909|427708 428060|427774|427289 429978 427664 orf19.12044|IPF22565.1|IPF1031.1|Contig4-3104_0016|orf6.7874|CA5138|CaO19.4575|CaO19.12044|IPF1031 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 430058 431908 - orf19.4574 430058 431908 1 431908 430058 431876 430206 orf19.12043|IPF18767.2|IPF1032.2|Contig4-3104_0015|orf6.2402|orf6.7873|CA5137|CaO19.4574|CaO19.12043|IPF1032 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 432146 434656 - orf19.4573 432146 434656 1 434656 432146 434656 432164 ZCF26|orf19.12042|IPF1034.2|IPF18133.2|Contig4-3104_0014|orf6.2403|orf6.7872|CA1083|CaO19.4573|IPF1034 Putative transcription factor with zinc cluster DNA-binding motif; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr4 432193 432319 + ntar_752 432193 432319 1 432193 432319 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 435219 436868 - orf19.4571 435219 436868 1 436868 435219 436868 435219 orf19.12040|IPF22577.1|IPF1036.2|Contig4-3104_0013|orf6.2405|CA1084|CaO19.4571|CaO19.12040|IPF1036 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 437184 437835 - orf19.4570 437184 437835 1 437835 437184 437692 437252 orf19.12039|IPF22643.1|IPF1038.2|Contig4-3104_0012|orf6.2406|CA1085|CaO19.12039|CaO19.4570|IPF1038 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 437980 438774 + orf19.4569 437980 438774 1 437980 438774 437980 438774 orf19.12038|IPF1039.2|IPF28306.1|Contig4-3104_0011|orf6.2407|CA1086|CaO19.4569|CaO19.12038|IPF1039 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr4 438721 441248 - orf19.4568 438721 441248 1 441248 438721 441248 438831 ZCF25 orf19.12037|IPF22554.1|IPF1040.3|Contig4-3104_0010|orf6.2408|orf6.3100|CA1544|CaO19.4568|IPF1040|IPF1040.2 Putative transcription factor with zinc cluster DNA-binding motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr4 442108 443019 - orf19.4567 442108 443019 1 443019 442108 443019 442108 orf19.12036|IPF22616.1|IPF1043.2|Contig4-3104_0008|orf6.3099|CA1543|CaO19.4567|HQD2|CaO19.12036|IPF1043 Catechol 1,2-dioxygenase (1,2-CTD), involved in degradation of aromatic compounds [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 443782 444363 - orf19.4566 443782 444363 1 444363 443782 444363 443782 orf19.12035|orf6.3098|IPF22632.1|IPF1044.1|Contig4-3104_0007|CA1542|CaO19.4566|CaO19.12035|ROT11 [NOT TRANSCRIBED?] Protein similar to S. cerevisiae Rot1p, which has roles in cytoskeletal dynamics and cell wall biosynthesis; predicted Kex2p substrate [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 444518 445801 - orf19.4565 444518 445801 1 445801 444518 445653 444727 BGL2 orf19.12034|orf6.3097|BGL21|IPF22613.1|IPF1046.1|Contig4-3104_0006|CA1541|CaO19.4565|CaO19.12034 1,3-beta-Glucosyltransferase, cell wall enzyme; one of multiple 1,3-beta-glucosyltransferases; mutant has cell-wall and growth defects, but wild-type 1,3- or 1,6-beta-glucan content; antigenic; virulence role in mouse systemic infection [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 446310 447530 - orf19.4563 446310 447530 1 447530 446310 447495 446380 orf19.12032|IPF22609.1|IPF1047.1|Contig4-3104_0004|orf6.3095|CA1540|CaO19.12032|CaO19.4563|IPF1047 Predicted ORF in Assemblies 19, 20 and 21; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 447674 449473 - orf19.4560 447674 449473 1 449473 447674 449240 447852 BFR1 orf19.12029|IPF22590.1|IPF1051.1|Contig4-3104_0002|orf6.3092|CA1539|CaO19.12029|CaO19.4560 Predicted ORF in Assemblies 19, 20 and 21; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 449775 451140 + orf19.2775 449775 451140 1 449775 451140 450184 451038 IDI1 orf19.12027|orf19.10291|IPF24623.1|IPF11947.2|IPF22675.1|IPF1053.1|Contig4-2553_0008|orf6.3090|orf6.6577|CA4116|orf19.4558|CaO19.10291|CaO19.2775|CA1538|IDI1.3eoc Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 450787 451084 - ntar_753 450787 451084 1 451084 450787 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 451463 452841 + orf19.2774 451463 452841 1 451463 452841 451524 452684 LAB5 orf19.10290|IPF24616.1|IPF11949.2|Contig4-2553_0006|orf6.6578|CA4117|LIS1|CaO19.10290|CaO19.2774 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 452759 452993 - ntar_754 452759 452993 1 452993 452759 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 453353 455779 + orf19.2772 453353 455779 1 453353 455779 453560 455701 HOS3 orf19.10288|IPF24590.1|IPF11952.2|Contig4-2553_0004|orf6.6580|CA4118|CaO19.10288|CaO19.2772|IPF11952 Histone deacetylase; similar to S. cerevisiae Hos3p; greater expression and longer mRNA in white cells, compared to opaque cells; has conserved deacetylation motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 457049 460753 + orf19.2771 457049 460753 1 457049 460753 457313 460738 BEM3 orf19.10287|IPF24667.1|IPF7085.2|orf6.6581|CA4119|CaO19.2771|CaO19.10287 Putative GTPase-activating protein (GAP) for Rho-type GTPase Cdc42p; involved in cell signaling pathways that control cell polarity; similar to S. cerevisiae Bem3p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 460800 462454 - orf19.2770.1 460800 462454 2 462454|461483 461729|460800 461741 461032 SOD1 orf19.10286.2|IPF24645.1|IPF7082.2|CA4120|SOD1.3 Cytosolic copper- and zinc-containing superoxide dismutase, involved in protection from oxidative stress and required for full virulence; alkaline upregulated by Rim101p; upregulated in the presence of human blood [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 462478 463389 - orf19.2770 462478 463389 1 463389 462478 463139 462681 orf19.10286|IPF24642.1|IPF7081.2|Contig4-2112_0004|orf6.6582|CA4121|CaO19.2770|CaO19.10286|IPF7081 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 463428 464211 + orf19.2769 463428 464211 1 463428 464211 463682 464065 orf19.10285|IPF24643.1|IPF7079.2|Contig4-2112_0005|Contig4-2513_0011|orf6.6583|CA4122|CaO19.10285|CaO19.2769|PBI2 Predicted ORF in Assemblies 19, 20 and 21; hyphal-induced expression; greater mRNA abundance observed in a cyr1 or ras1 homozygous null mutant than in wild type [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 464911 468512 + orf19.2768 464911 468512 1 464911 468512 464968 468435 AMS1 orf19.10284|IPF24664.1|IPF7076.2|Contig4-2513_0006|orf6.6584|CA4123|CaO19.2768|CaO19.10284 Putative alpha-mannosidase; transcription is regulated by Nrg1p; induced during cell wall regeneration [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr4 465131 466242 - ntar_755 465131 466242 1 466242 465131 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 466692 466868 - ntar_756 466692 466868 1 466868 466692 466849 466721 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 467192 467367 - ntar_757 467192 467367 1 467367 467192 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 470797 471516 - orf19.2767 470797 471516 1 471516 470797 471464 471123 PGA59 orf19.10283|IPF24649.1|IPF20008.1|Contig4-2513_0002|orf6.6585|CA4124|CaO19.10283|CaO19.2767|IPF20008 Putative GPI-anchored protein of unknown function; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 474974 476031 + ntar_758 474974 476031 1 474974 476031 475154 475282 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 477368 477591 - ntar_759 477368 477591 1 477591 477368 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 479521 479829 + orf19.2766 479521 479829 1 479521 479829 479521 479829 orf19.10282|IPF24672.1|IPF29029.1|Contig4-2938_0017|orf6.6586|CaO19.2766|CaO19.10282 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 480558 481661 + orf19.2765 480558 481661 1 480558 481661 480635 481276 PGA62 orf19.10281|FLO1|orf6.6587|IPF20161.1|IPF29011.1|Contig4-2938_0018|Contig4-2938_0019|CA4125|CaO19.2765|CaO19.10281|IPF20161 Putative GPI-anchored protein; fluconazole-induced; transcriptionally regulated by iron; expression greater in high iron; induced during cell wall regeneration; Cyr1p or Ras1p downregulated; transcription is positively regulated by Tbf1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 482097 482549 + ntar_760 482097 482549 1 482097 482549 482166 482315 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 482817 485664 - orf19.2763 482817 485664 1 485664 482817 485641 483227 orf19.10279|IPF6631|IPF24580.1|IPF6631.1|Contig4-2938_0022|orf6.6589|CA4126|CaO19.10279|CaO19.2763 Protein not essential for viability; orf19.10279 possibly transcriptionally regulated upon hyphal formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 486005 486874 - orf19.2762 486005 486874 1 486874 486005 486718 486188 AHP1 orf19.10278|orf6.6590|IPF24637.1|IPF6629.2|IPF6629|Contig4-2938_0023|CA4127|AHP11|CaO19.2762|CaO19.10278 Putative alkyl hydroperoxide reductase; immunogenic in mouse; biofilm-induced; fluconazole-induced; amphotericin B, caspofungin, alkaline downregulated; induced in core stress response; regulated by Ssk1p, Nrg1p, Tup1p, Ssn6p, Hog1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 487459 488663 - orf19.2761 487459 488663 1 488663 487459 488449 487652 orf19.10277|IPF24625.1|IPF11995.2|Contig4-2938_0025|orf6.1334|orf6.6591|CA0427|CaO19.2761|GPI11|IPF11995 Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide in yhb1 mutant; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 487485 487911 + ntar_761 487485 487911 1 487485 487911 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 488928 493544 + orf19.2760 488928 493544 1 488928 493544 489039 493301 orf19.10276|IPF24586.1|IPF11996.2|Contig4-3083_0006|orf6.1333|orf6.6592|orf6.6593|CA0426|CFT1|CaO19.2760 Putative protein of unknown function; heterozygous null mutant exhibits hypersensitivity to parnafungin and cordycepin in the C. albicans fitness test; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 493470 495452 - orf19.2758 493470 495452 1 495452 493470 495160 493613 PGA38 orf19.10273|orf19.10272|IPF11998.3|IPF17815.2|orf6.1331|orf6.3591|orf6.1332|orf6.3590|CA1898|orf19.2759|IPF11998|IPF11998.2 Putative GPI-anchored protein of unknown function; repressed during cell wall regeneration [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 495902 497388 + orf19.2757 495902 497388 1 495902 497388 496267 497265 orf19.10271|IPF12002.2|IPF29008.1|Contig4-1891_0003|orf6.3589|CA1897|CaO19.2757|CaO19.10271|IPF12002 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 497475 498432 + orf19.2756 497475 498432 1 497475 498432 497593 498231 orf19.10270|IPF24630.1|IPF12003.1|Contig4-1891_0004|orf6.3588|CA1896|ERD2|CaO19.2756|CaO19.10270 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 498174 499353 - orf19.2755 498174 499353 1 499353 498174 499171 498434 orf19.10269|IPF24655.1|IPF24662.1|IPF10202.2|IPF12004.2|Contig4-1891_0005|orf6.3587|CA1894|PRE7.5f|PRE7.exon1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 499454 500291 - orf19.2754 499454 500291 1 500291 499454 500130 499801 orf19.10268|IPF24668.1|IPF10200.2|Contig4-2786_0003|orf6.3586|CA1893|CaO19.10268|TIM13|CaO19.2754 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 501224 504485 + orf19.2753 501224 504485 1 501224 504485 501568 504402 ZCF15|orf19.10267|IPF24570.1|IPF10197.2|Contig4-2786_0005|orf6.3585|CA1892|CaO19.2753|CaO19.10267|IPF10197 Predicted zinc-finger protein of unknown function [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr4 504438 508889 - orf19.2752 504438 508889 1 508889 504438 508877 504621 ADR1 orf19.10266|IPF24651.1|IPF10196.2|Contig4-2786_0008|orf6.3584|CA1891|CaO19.2752|CaO19.10266|IPF10196 Putative transcription factor with zinc finger DNA-binding motif; similar to S. cerevisiae Adr1p but mutant phenotype suggests that it has a different set of target genes; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 512237 514217 + orf19.2751 512237 514217 1 512237 514217 512530 514077 orf19.10265|IPF16120.2|IPF13270.2|Contig4-2217_0002|Contig4-2217_0011|orf6.2533|orf6.3583|YOL119C|CA1169|CaO19.2751|Mch4p|IPF16120.3eoc|IPF13270.1 Predicted membrane transporter, member of the monocarboxylate porter (MCP) family, major facilitator superfamily (MFS); alkaline upregulated by Rim101p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 513467 515886 - orf19.2749 513467 515886 1 515886 513467 515620 514148 orf19.10263|IPF24610.1|IPF13268.1|Contig4-2217_0003|orf6.2535|CA1170|CaO19.10263|CaO19.2749|IPF13268 Predicted ORF in Assemblies 19, 20 and 21; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 517298 520482 + orf19.2748 517298 520482 1 517298 520482 517410 520334 ARG83|orf19.10262|IPF24568.1|IPF13264.2|Contig4-2217_0009|Contig4-2945_0026|orf6.2536|CA1171|CaO19.10262|CaO19.2748|IPF13264 Predicted zinc-finger protein of unknown function; clade-associated gene expression; similarity to S. cerevisiae Arg81p, which is a transcription factor involved in the regulation of arginine-responsive genes [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr4 520353 521195 - ntar_762 520353 521195 1 521195 520353 521128 521006 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 521435 521941 + ntar_763 521435 521941 1 521435 521941 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 521651 521948 - ntar_764 521651 521948 1 521948 521651 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 522095 522278 - ntar_765 522095 522278 1 522278 522095 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 523118 523480 - ntar_766 523118 523480 1 523480 523118 523372 523202 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 523964 527185 + orf19.2747 523964 527185 1 523964 527185 523970 527059 RGT1 orf19.10261|IPF24678.1|IPF14445.2|orf6.2537|CA1172|CaO19.2747|CaO19.10261 Transcriptional repressor involved in the regulation of glucose transporter genes; has zinc-cluster; similar to S. cerevisiae Rgt1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr4 527249 529488 - orf19.2746 527249 529488 1 529488 527249 529387 527495 orf19.10260|IPF14444.3|IPF28996.1|Contig4-3001_0019|orf6.4702|CA2702|EMP70|CaO19.2746|IPF14444.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 529990 531366 - orf19.2745 529990 531366 1 531366 529990 531366 529990 UME7|orf19.10259|IPF15893.2|IPF15350.2|Contig4-1974_0005|orf6.4701|orf6.887|CA0215|CaO19.2745|IPF15350 [NOT TRANSCRIBED?] Putative transcription factor with zinc cluster DNA-binding motif; similar to S. cerevisiae Ume6p, which is a transcription factor involved in the regulation of meiotic genes [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 530471 530830 + ntar_767 530471 530830 1 530471 530830 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 531666 533641 - orf19.2743 531666 533641 1 533641 531666 533641 531821 orf19.10257|IPF19520.2|IPF15357.2|Contig4-1974_0001|Contig4-2458_0009|RPH1|CaO19.2743 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr4 534009 534540 + orf19.2742 534009 534540 1 534009 534540 534009 534347 orf19.10256|IPF19112.1|orf6.884|CaO19.2742 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr4 534332 536746 - orf19.2740 534332 536746 1 536746 534332 536699 534369 orf19.10255|IPF17364.2|IPF14414.3|Contig4-1912_0001|Contig4-1912_0002|Contig4-2105_0004|orf6.4696|orf6.634|orf6.4697|CA2700|CaO19.2740|IPF1441|CA2701|IPF14414.exon2|IPF15360.2|IPF14414.exon1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 536916 538749 - orf19.2739 536916 538749 1 538749 536916 538698 536980 orf19.10253|IPF19958.1|IPF19837.1|Contig4-1912_0004|Contig4-2105_0002|Contig4-2105_0003|orf6.4695|orf6.633|CA2699|RLF2|CaO19.2739 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 538980 541881 - orf19.2738 538980 541881 1 541881 538980 541600 539120 SUL2 orf19.10252|orf6.4694|SUL1|IPF14417.2|IPF28993.1|Contig4-2105_0001|CA2698 Protein described as a sulfate transporter; transcription is negatively regulated by Sfu1p; induced upon biofilm formation; amphotericin B induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 543715 546119 - orf19.2737 543715 546119 1 546119 543715 546002 543774 orf19.10251|IPF24588.1|IPF9167.2|Contig4-2731_0006|orf6.4693|CA2697|CaO19.10251|CaO19.2737|IPF9167|CA1296|IPF18712|IPF18712.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 546291 546859 + ntar_768 546291 546859 1 546291 546859 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 546733 547731 - orf19.2736 546733 547731 1 547731 546733 547581 547141 orf19.10250|IPF24632.1|IPF9169.2|Contig4-2731_0003|orf6.4692|CA2696|CaO19.2736|BUR6|CaO19.10250|IPF9169 Predicted ORF in Assemblies 19, 20 and 21; flucytosine induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 547880 549460 - orf19.2735 547880 549460 2 549460|549195 549428|547880 549178 548009 SEN2 orf19.10249|IPF24615.1|IPF9170.2|Contig4-2731_0002|orf6.4691|CaO19.10249|CaO19.2735|CA2695|IPF9070 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to toxic ergosterol analog, and to amphotericin B; has intron in 5'-UTR [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr4 550208 551472 + orf19.2734 550208 551472 1 550208 551472 550364 551371 orf19.10248|IPF9171|IPF9171.1|IPF29007.1|Contig4-2731_0001|orf6.4690|CA2694|SCD99|CaO19.2734 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 551548 553259 + orf19.2733 551548 553259 1 551548 553259 551637 553190 orf19.10246|orf19.10247|IPF9173.2|IPF29004.1|orf6.4688|orf6.4689|CA2692|CA2693|orf19.2732|IPF9173.5f Putative protein of unknown function, transcription is activated in the presence of elevated CO2; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 552787 553566 - orf19.2731 552787 553566 1 553566 552787 553566 553228 orf19.10245|IPF10251.3|orf6.2523|orf6.4687|orf6.4698|CaO19.2731 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr4 553876 555758 + orf19.2730 553876 555758 1 553876 555758 553938 555758 orf19.10244|IPF24597.1|IPF20076.1|Contig4-2458_0008|Contig4-2458_0009|orf6.2522|orf6.4699|orf6.885|CA1163|RPH2|CaO19.2730|CaO19.10244|IPF15357 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chr4 555909 557798 + orf19.2728 555909 557798 1 555909 557798 555926 557695 orf19.10242|IPF24601.1|IPF10258.2|Contig4-2458_0004|orf6.2520|CA1162|RAD24|CaO19.2728|CaO19.10242|IPF10258 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 557629 558692 - orf19.2727 557629 558692 1 558692 557629 558606 557845 GRX3 orf19.10241|IPF24624.1|IPF10259.2|Contig4-2458_0002|orf6.2519|CA1161|CaO19.10241|CaO19.2727 Protein described as glutaredoxin; flucytosine induced; regulated by Gcn4p; repressed in response to amino acid starvation (3-aminotriazole treatment) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 558890 560294 - orf19.2726 558890 560294 1 560294 558890 559897 558959 orf19.10240|IPF24621.1|IPF10262.2|orf6.2518|CA1160|CaO19.2726|CaO19.10240|IPF10262 Predicted ORF in Assemblies 19, 20 and 21; Plc1p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 558918 559995 + ntar_769 558918 559995 1 558918 559995 559422 559586 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 566926 567228 - orf19.2725 566926 567228 1 567228 566926 567228 566926 IPF29033.1|orf6.325|CaO19.2725 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 571598 573562 + orf19.2724 571598 573562 1 571598 573562 571922 573418 orf19.10239|IPF6399.1|IPF17321.2|Contig4-1642_0002|Contig4-2420_0009|orf6.1970|orf6.2695|CA0817|CaO19.2724|IPF6339 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 574539 574974 - ntar_770 574539 574974 1 574974 574539 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 577341 579343 + orf19.2723 577341 579343 1 577341 579343 577406 577852 HIT1 orf19.10238|IPF19187.2|IPF6402.2|Contig4-1801_0001|orf6.2696|orf6.678|CA1271|CaO19.2723 Protein not essential for viability; similar to S. cerevisiae Hit1p, which is required for growth at high temperature [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 577995 579247 - orf19.2722 577995 579247 1 579247 577995 579236 578214 CGR1 orf19.10237|IPF6403.2|IPF18718.1|Contig4-1801_0004|orf6.2697|orf6.677|CA1272|CaO19.2722 Possible negative regulator of yeast-form growth; induced upon growth cessation at yeast-hyphal transition or during planktonic growth; physically interacts with Msi3p, an HSP70 family member; similar to rat anti-aging gene, SMP30 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 579405 580539 - orf19.2721 579405 580539 1 580539 579405 580529 579492 orf19.10236|IPF6404.2|IPF29006.1|Contig4-1801_0005|Contig4-2673_0012|orf6.2698|orf6.676|CA0150|CaO19.2721|CDC123 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 580731 582510 + orf19.2720 580731 582510 1 580731 582510 580782 582416 orf19.10235|IPF19188.2|IPF6406.2|Contig4-2673_0010|orf6.2699|orf6.675|CA1273|CCT4|CaO19.2720 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 582340 584254 - orf19.2717 582340 584254 1 584254 582340 584201 582507 SAS10 orf19.10232|IPF24603.1|IPF6410.2|Contig4-2673_0009|orf6.2702|CA1274|CaO19.2717 Predicted ORF in Assemblies 19, 20 and 21; mutation confers resistance to 5-fluorocytosine (5-FC); repressed upon high-level peroxide stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 584388 585884 + orf19.2715 584388 585884 1 584388 585884 584483 585841 RPC53 orf19.10230|IPF24613.1|IPF19910.1|Contig4-2673_0008|orf6.2704|CA1275|CaO19.2715 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 586425 588897 + orf19.2713 586425 588897 2 586425|586915 586850|588897 586425 588897 orf19.10228|orf19.10229|IPF6415.2|IPF19655.2|Contig4-2673_0005|Contig4-2673_0006|orf6.2706|orf6.2729|orf6.2705|orf6.2730|CA1276|orf19.2714|MSH5|CA1294|MSH5.3f [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 588809 591281 - orf19.2712 588809 591281 1 591281 588809 591191 588894 HCA4 orf19.10227|IPF24582.1|IPF6418.1|Contig4-2673_0001|orf6.2728|CaO19.2712|CaO19.10227|CA1293 Putative role in regulation of biogenesis of the cell wall; upregulated in biofilm [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 591356 592340 - orf19.2711.1 591356 592340 2 592340|592187 592266|591356 592276 591485 IPF24628.1|IPF6419.2|Contig4-2190_0001|CA1292|SRB2.3f|SRB2.3 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 592464 594972 + orf19.2711 592464 594972 1 592464 594972 592522 594915 orf19.10226|IPF24584.1|IPF16752.2|Contig4-2190_0002|orf6.2727|CA1291|CaO19.10226|ELP2|CaO19.2711|IPF16752 Predicted ORF in Assemblies 19, 20 and 21; downregulated in core stress response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 595181 596146 + orf19.2710 595181 596146 1 595181 596146 595271 595915 orf19.10225|IPF24631.1|IPF16212.2|Contig4-1957_0003|Contig4-2190_0003|orf6.2726|CA1290|CaO19.10225|GLC8|CaO19.2710|IPF16212 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 595868 597406 - orf19.2709 595868 597406 1 597406 595868 597368 596085 ZUO1 orf19.10224|IPF16213.3|IPF29003.1|Contig4-1957_0002|orf6.2725|CA1289|CaO19.2709|IPF16213.2 Protein likely to be essential for growth, based on an insertional mutagenesis strategy; similar to S. cerevisiae Zuo1p, which is a cytosolic ribosome-associated chaperone [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 597461 598402 - orf19.2708 597461 598402 1 598402 597461 598349 597582 orf19.10223|IPF24626.1|IPF14356.2|Contig4-1779_0002|orf6.1233|CA0377|CaO19.2708|IPF14356 Predicted ORF in Assemblies 19, 20 and 21; nonessential [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 598567 599013 - orf19.2707.1 598567 599013 1 599013 598567 598959 598762 QCR9 IPF24583.1|IPF14357.1|Contig4-1779_0001|CA0376 ORF Predicted by Annotation Working Group; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 599218 600867 - orf19.2706 599218 600867 1 600867 599218 600732 599371 CRH11 orf19.10221|orf6.1231|IPF24611.1|IPF14360.2|Contig4-1894_0003|CA0375|CRH1|CaO19.2706|CaO19.10221 GPI-anchored cell wall protein, putative ortholog of S. cerevisiae Crh1p; predicted glycosyl hydrolase domain; similar to Csf4p and to antigenic A. fumigatus Aspf9; predicted Kex2p substrate; caspofungin-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 599377 600660 + ntar_771 599377 600660 1 599377 600660 599669 599977 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 602846 603166 + orf19.2704 602846 603166 1 602846 603166 602846 603166 orf19.10219|IPF24674.1|IPF29030.1|orf6.5492|CaO19.10219|CaO19.2704 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 603191 604978 + orf19.2703 603191 604978 1 603191 604978 603321 604889 orf19.10218|orf6.5491|IPF24607.1|IPF5045.1|Contig4-2809_0011|CA3266|CaO19.10218|CaO19.2703|IPF5045 Transcriptionally regulated by iron; expression greater in low iron; increased expression observed in an ssr1 homozygous null mutant; similar to S. cerevisiae Ymr171cp; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 604215 605286 - ntar_772 604215 605286 1 605286 604215 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 605491 606256 + orf19.2701 605491 606256 1 605491 606256 605540 606058 orf19.10216|IPF24639.1|IPF5043.1|Contig4-2809_0006|orf6.5489|CA6206|CaO19.10216|CaO19.2701|IPF5043 Predicted ORF in Assemblies 19, 20 and 21; greater mRNA abundance observed in a cyr1 or ras1 homozygous null mutant than in wild type [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 606557 608670 + orf19.2699 606557 608670 1 606557 608670 606596 608542 ABP1 orf19.10214|IPF24596.1|IPF5041.1|Contig4-2809_0004|orf6.5487|CA3265|CaO19.10214|CaO19.2699 Protein similar to S. cerevisiae Abp1p, which is an actin-binding protein of the cortical actin cytoskeleton; caspofungin induced; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 608509 609246 - orf19.2698 608509 609246 1 609246 608509 609084 608758 orf19.10213|IPF24663.1|IPF5035.1|Contig4-2809_0003|orf6.5486|CA3264|CaO19.2698|CaO19.10213|IPF5035 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 609473 615271 + orf19.2697 609473 615271 1 609473 615271 609473 615169 orf19.10212|IPF24635.1|IPF19781.1|Contig4-2782_0001|Contig4-2809_0001|orf6.5485|CA3263|UBR2|CaO19.10212|CaO19.2697|UBR12 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr4 615118 620766 - orf19.2695 615118 620766 1 620766 615118 620665 615302 UBR1 orf19.10210|IPF24638.1|IPF5026.2|Contig4-2782_0002|orf6.5483|CA3262|CaO19.10210|CaO19.2695|UBR11.3f|UBR11.3 Protein similar to S. cerevisiae Ubr1p ubiquitin-protein ligase; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 621459 622895 + orf19.2694 621459 622895 1 621459 622895 621567 622796 TYS1 orf19.10209|IPF24614.1|IPF5023.2|Contig4-2782_0005|Contig4-2865_0013|orf6.5482|CA3261|CaO19.2694|CaO19.10209 Putative tRNA-Tyr synthetase; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 622789 623768 - orf19.2693 622789 623768 1 623768 622789 623611 622934 GST2 orf19.10208|YNL229C|Contig4-2782_0006|IPF24629.1|IPF7968.2|IPF7968|Contig4-2865_0012|orf6.5481|CA3260|CaO19.10208|CaO19.2693 Increased transcription is observed upon benomyl treatment transcription and in populations of cells exposed to fluconazole over multiple generations; regulated by Nrg1p, Tup1p; induced by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr4 624374 625131 - orf19.2691 624374 625131 1 625131 624374 625096 624374 orf19.10206|IPF7970.1|IPF17602.2|Contig4-2865_0010|orf6.4801|orf6.5479|CA3259|CaO19.2691|IPF7970 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr4 627499 627570 + tt(ugu)1 627499 627570 1 627499 627570 tT(UGU)1.2 tRNA-Thr predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 627733 630718 + orf19.2690 627733 630718 1 627733 630718 627864 630557 orf19.10205|IPF24572.1|IPF7974.1|Contig4-2865_0004|orf6.4800|CA2773|MGM1|CaO19.2690|CaO19.10205 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 630599 633263 - orf19.2688 630599 633263 1 633263 630599 633200 630681 NAN1 orf19.10203|IPF24577.1|IPF20112.1|Contig4-2865_0003|orf6.4798|CA2772|CaO19.10203|CaO19.2688|IPF20112 Predicted ORF in Assemblies 19, 20 and 21; physically interacts with TAP-tagged Nop1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 633405 633989 + orf19.2687.1 633405 633989 1 633405 633989 633514 633732 IPF24589.1|IPF7977.1|Contig4-2865_0002|CA2771|RPB10 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 633900 635997 - orf19.2686 633900 635997 1 635997 633900 635720 633978 orf19.10201|IPF19440.2|IPF7980.2|Contig4-2865_0001|orf6.116|orf6.4796|CA2770|CPS1|CaO19.2686 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 636171 636392 + ntar_773 636171 636392 1 636171 636392 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 636424 636588 - ntar_774 636424 636588 1 636588 636424 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 637631 638129 - ntar_775 637631 638129 1 638129 637631 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 639638 641385 + orf19.2685 639638 641385 1 639638 641385 639770 640798 PGA54 orf19.10200|IPF24619.1|IPF15870.2|Contig4-2214_0002|orf6.4795|CA2769|CaO19.2685|CaO19.10200|IPF15870 Putative GPI-anchored protein; hyphal induced; Hog1p-downregulated; induced in a cyr1 or efg1 homozygous null mutant; shows colony morphology-related gene regulation by Ssn6p; upregulated in an RHE model; mRNA binds to She3p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 641752 644341 + orf19.2684 641752 644341 1 641752 644341 641845 644280 orf19.10199|IPF24581.1|IPF17011.2|orf6.4794|CA2768|CaO19.10199|SLK19|CaO19.2684|IPF17011 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 644700 645891 + orf19.2682 644700 645891 1 644700 645891 644984 645811 orf19.10197|IPF19155.2|IPF14884.2|Contig4-2016_0002|orf6.4792|orf6.742|CA2767|TOA1|CaO19.2682 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 646919 647896 + orf19.2681 646919 647896 1 646919 647896 646919 647896 RBT7 orf19.10196|IPF14885.2|IPF29009.1|Contig4-2806_0001|orf6.4791|orf6.741|CA0169|CaO19.2681 Protein with similarity to RNase T2 enzymes, has putative secretion signal; expression is Tup1p-repressed [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 648504 648869 - ntar_776 648504 648869 1 648869 648504 648671 648510 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 649004 654656 + orf19.2680 649004 654656 1 649004 654656 649268 654511 orf19.10195|IPF24640.1|IPF6900.3|Contig4-2806_0003|Contig4-2806_0005|orf6.5554|orf6.740|CA3319|CaO19.2680|DRS25|DRS25.3eoc|IPF6900.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 654524 657384 - orf19.2678 654524 657384 1 657384 654524 657311 654609 BUB1 orf19.10193|IPF24575.1|IPF6898.2|Contig4-2806_0006|Contig4-2806_0007|orf6.5556|CA3320|CaO19.2678|CaO19.10193|IPF6898 Predicted ORF in Assemblies 19, 20 and 21; mutation confers increased sensitivity to nocodazole [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 657565 659915 + orf19.2677 657565 659915 1 657565 659915 657654 659519 orf19.10192|IPF24578.1|IPF24606.1|IPF6895.2|IPF6896.2|Contig4-2806_0009|orf6.5557|CA3321|IPF6896.5f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 659440 660558 - orf19.2676 659440 660558 1 660558 659440 660489 659593 orf19.10191|IPF24620.1|IPF6894.2|Contig4-2806_0011|orf6.5558|CA3323|CaO19.2676|IKI1|CaO19.10191 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 660680 664081 + orf19.2675 660680 664081 1 660680 664081 660680 663964 orf19.10190|IPF24671.1|IPF6893.2|orf6.5559|CA3324|HSH155|CaO19.10190|CaO19.2675|IPF6893 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr4 664111 665186 - orf19.2674 664111 665186 1 665186 664111 665139 664111 orf19.10189|IPF24618.1|IPF6890.2|orf6.5560|CA3325|CaO19.2674|CaO19.10189|IPF6890 Putative transcription factor with zinc finger DNA-binding motif; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chr4 665650 667152 + orf19.2673 665650 667152 1 665650 667152 665708 666727 orf19.10188|IPF24617.1|IPF6889.2|Contig4-1603_0002|orf6.5561|CA3326|CaO19.10188|CaO19.2673|IPF6889 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 668175 670620 + orf19.2672 668175 670620 1 668175 670620 668328 670370 NCP1 orf19.10187|PRD1|RED|IPF24595.1|IPF10561.2|Contig4-2240_0006|orf6.5562|CA3327|CaO19.10187|CaO19.2672 NADPH-cytochrome P450 reductase, acts with Erg11p in sterol 14 alpha-demethylation in ergosterol biosynthesis; subject to hypoxic regulation; ketoconazole-induced; caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 670680 671017 - ntar_777 670680 671017 1 671017 670680 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 671223 672727 + orf19.2671 671223 672727 1 671223 672727 671384 672727 orf19.10186|orf6.154|IPF24612.1|IPF10564.2|Contig4-2584_0001|orf6.5563|CA3328|CaO19.2671|CaO19.10186|IPF10564 Predicted ORF in Assemblies 19, 20 and 21; Plc1p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chr4 672766 673911 - orf19.2670 672766 673911 1 673911 672766 673769 672894 orf19.10185|IPF12430.2|IPF12162.1|Contig4-2584_0002|orf6.1626|orf6.5564|CA3329|CaO19.10185|CaO19.2670|IPF12162 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 674364 678707 - orf19.2669 674364 678707 1 678707 674364 678707 674364 IPF12161.2|Contig4-2757_0014|Contig4-3083_0024|orf6.5565|CA3330|CaO19.2669|POL21.3f|POL21.3 Predicted ORF in retrotransposon Tca4 with similarity to the Pol region of retrotransposons encoding reverse transcriptase, protease and integrase; downstream from RHD2 with similarity to the Gag region encoding nucleocapsid-like protein [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 679360 680277 - orf19.2668 679360 680277 1 680277 679360 680277 679360 RHD2 IPF12158.1|IPF12159.2|Contig4-3083_0025|Contig4-3083_0027|orf6.5566|CA3332|POL21.5f|GAG Predicted ORF in retrotransposon Tca4 with similarity to the Gag region encoding nucleocapsid-like protein; overlaps blocked reading frame orf19.2668.1; decreased expression in hyphae compared to yeast-form cells [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr4 680863 681944 + orf19.2667 680863 681944 1 680863 681944 680960 681850 RPF1 orf19.10184|IPF12428.1|IPF12157.3|Contig4-3083_0028|orf6.1627|orf6.5567|CA0599|CaO19.2667|IPF12428 Predicted ORF in Assemblies 19, 20 and 21; essential for growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 682344 686469 + orf19.2665 682344 686469 1 682344 686469 682600 686337 MSN5 orf19.10182|orf19.10183|IPF18929.1|IPF24579.1|IPF29005.1|IPF12426.2|Contig4-3083_0029|orf6.1628|orf6.1629|CA0601|CA0600|orf19.2666|MSN5.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 686644 689599 + orf19.2664 686644 689599 1 686644 689599 686742 689441 orf19.10181|IPF24573.1|IPF16761.2|Contig4-2457_0002|orf6.1472|CA0502|orf19.67|MKT1|CaO19.10181|CaO19.2664|IPF16761 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 689530 690845 - orf19.1440.2 689530 690845 1 690845 689530 690462 690280 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 692395 692595 - orf19.1440.1 692395 692595 1 692595 692395 692595 692395 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 693529 694393 - ntar_778 693529 694393 1 694393 693529 694393 694160 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 695268 696247 - ntar_779 695268 696247 1 696247 695268 695877 695668 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 697401 699218 + orf19.1440 697401 699218 1 697401 699218 697817 698932 orf19.9015|IPF25887.1|IPF10568.1|Contig4-2265_0003|orf6.1052|CA0279|CaO19.1440|IPF10568 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 699573 700972 + orf19.1439 699573 700972 1 699573 700972 699814 700899 IPK1 orf19.9013|IPF25886.1|IPF10566.1|Contig4-2265_0006|orf6.1053|CA0280|CaO19.1439|IPF10566 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 701161 702384 - orf19.1438 701161 702384 1 702384 701161 702384 701161 orf19.9012|IPF19419.2|IPF10565.1|Contig4-2265_0007|orf6.1054|orf6.155|CA0281|CPD2|CaO19.1438|IPF10565|IPF10564.3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 702777 704120 - orf19.3362 702777 704120 1 704120 702777 704120 702777 orf19.10870|IPF23891.1|IPF15758.2|Contig4-2353_0001|orf6.1783|CaO19.10870|CaO19.3362 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr4 704469 706878 - orf19.3363 704469 706878 1 706878 704469 706651 704522 VTC4 orf19.10871|IPF16674.3|IPF15753.2|Contig4-2353_0002|orf6.1784|orf6.2574|CA0697|CaO19.3363 Protein described as polyphosphate synthetase; decreased expression in hyphae compared to yeast-form cells; fungal-specific (no human or murine homolog); virulence-group-correlated expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 707090 708065 - orf19.3364 707090 708065 1 708065 707090 707956 707468 orf19.10872|IPF10394.1|IPF16673.2|Contig4-2353_0007|Contig4-2386_0008|orf6.1785|orf6.2575|CA1196|CaO19.3364|IPF10394 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr4 708418 709939 - orf19.3365 708418 709939 1 709939 708418 709745 708588 DAO2 orf19.10873|IPF10395.2|IPF18896.1|Contig4-2386_0006|orf6.1786|orf6.2576|CA0699|IFG2.5f|CA1197|IFG1 Putative D-amino acid oxidase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 710025 711252 + orf19.3366 710025 711252 1 710025 711252 710542 711252 CSH3 orf19.10874|orf6.1787|IPF23895.1|IPF10396.2|SHR3|Contig4-2386_0003|orf6.2577|CA0700|CaO19.3366 Functional homolog of S. cerevisiae Shr3p, which is a chaperone specific for amino acid permeases; localized to ER; required for wild-type amino-acid responsive hyphal growth and for mouse systemic virulence; regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 711501 712241 + orf19.3366.1 711501 712241 2 711501|711834 711557|712241 711501 712028 IPF23888.1|IPF10397.2|CA0701|IPF10397 ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 712381 713456 + orf19.3367 712381 713456 1 712381 713456 712422 713297 orf19.10875|IPF10399.1|IPF16677.2|Contig4-2386_0001|orf6.2578|orf6.2893|CA1198|MRPL22|CaO19.3367|IPF10399 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 713377 713682 - orf19.3368 713377 713682 1 713682 713377 713682 713377 IPF28792.1|orf6.2892|CaO19.3368 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 716802 718097 + orf19.3369 716802 718097 1 716802 718097 717306 718097 MOH1 orf19.10876|IPF10404.2|IPF28786.1|Contig4-1807_0003|Contig4-2147_0004|orf6.2579|orf6.2891|CA1199|CaO19.3369|IPF10404 Protein similar to S. cerevisiae Moh1p; transcription is induced in response to alpha pheromone in SpiderM medium; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr4 718829 721363 - orf19.3370 718829 721363 1 721363 718829 721235 718950 DOT4 orf19.10878|orf6.2580|IPF17685.3|IPF15624.1|Contig4-1346_0001|Contig4-1346_0002|Contig4-2147_0001|Contig4-2147_0003|orf6.2581|orf6.2890|CA1406|CaO19.3370|UBP10 Protein similar to ubiquitin C-terminal hydrolase; localizes to cell surface of hyphal cells, but not yeast-form cells; repressed upon high-level peroxide stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr4 721831 723948 - orf19.3371 721831 723948 1 723948 721831 723842 722013 orf19.10879|orf19.10880|IPF23892.1|IPF15627.2|Contig4-2147_0005|orf6.140|orf6.2889|orf6.2888|CA1405|CA1404|orf19.3372|IPF19554.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 724095 725966 - orf19.3373 724095 725966 1 725966 724095 725966 724095 orf19.10881|IPF13110.3|IPF14155.1|Contig4-2242_0002|orf6.141|orf6.2887|CA1403|RIM4|CaO19.3373|IPF14155 Putative protein of unknown function, transcription is upregulated in clinical isolates from HIV+ patients with oral candidiasis; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 724104 724852 + ntar_780 724104 724852 1 724104 724852 724617 724799 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 726613 727428 - orf19.3374 726613 727428 1 727428 726613 727428 726613 ECE1 orf19.10882|IPF23894.1|IPF14152.1|Contig4-2242_0004|orf6.2886|CA1402|CaO19.10882|CaO19.3374 Protein comprising eight 34-residue repeats; hyphal-specific expression increases with extent of elongation of the cell; regulated by Rfg1p, Nrg1p, Tup1p, Cph1p, Efg1p, Hog1p, farnesol, phagocytosis; may contribute to biofilm formation [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 730626 731213 - orf19.3375 730626 731213 1 731213 730626 731213 730626 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 733260 733784 - orf19.3376 733260 733784 1 733784 733260 733784 733260 orf19.10885|IPF16001.1|IPF13247.1|Contig4-1821_0002|orf6.1152|orf6.2936|CA0339|CaO19.3376|IPF13247 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr4 734794 735523 - orf19.3378 734794 735523 1 735523 734794 735490 734939 orf19.10886|IPF16006.2|IPF13252.1|Contig4-2366_0003|orf6.1150|orf6.2935|CA0338|CaO19.3378|IPF13252 Predicted ORF in Assemblies 19, 20 and 21; regulated by Tsa1p, Tsa1Bp in minimal media at 37 deg [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 736770 737022 - ntar_781 736770 737022 1 737022 736770 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 738545 741271 - orf19.3380 738545 741271 1 741271 738545 741271 738545 HWP2 orf19.10888|PGA8|IPF23887.1|IPF14331.2|Contig4-2768_0012|Contig4-2768_0013|orf6.2933|CA1430|CaO19.3380|CaO19.10888|IPF14331 Putative GPI-anchored, glycosylated cell wall protein, required for filamentous growth on some solid media; null mutant exhibits delayed virulence; expressed in hyphae; regulated by Efg1p, Tup1p; has similarity to Hwp1p and Rbt1p domains [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 745268 747433 - orf19.1327 745268 747433 1 747433 745268 747433 745268 RBT1 orf19.8907|orf19.10892|ECE99|IPF19252.2|IPF15385.2|IPF23893.1|IPF16136.1|Contig4-2768_0006|orf6.4889|orf6.489|orf6.2929|CA2830|orf19.3384|CaO19.1327|RBT99 Cell wall protein with similarity to Hwp1p, required for virulence; predicted to be cell-wall attached and glycosylated; Tup1p repressed; serum, hyphal and alkaline induced; farnesol, alpha factor induced; Rfg1p-, Rim101p-regulated [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 750584 752933 + orf19.1326 750584 752933 1 750584 752933 750752 752818 orf19.8906|IPF26011.1|IPF14593.2|Contig4-2287_0002|orf6.4888|CA2829|LPF13|CaO19.8906|CaO19.1326|IFA7 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr4 752918 754790 - orf19.1325 752918 754790 1 754790 752918 754755 752971 ECM38 orf19.8905|IPF26013.1|IPF17026.2|orf6.4887|CA2828|CSA99|CaO19.1325|CaO19.8905|IPF17026 Alkaline upregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr4 755369 758385 + orf19.1324 755369 758385 1 755369 758385 755390 758362 RAD2 orf19.8904|IPF26007.1|IPF19770.1|orf6.4886|CA2827|CaO19.1324|RAD13|CaO19.8904 Ortholog of S. cerevisiae RAD2, nucleotide excision repair nuclease; null mutant is extremely sensitive to UV irradiation; transcription is upregulated upon interaction with macrophages [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 758495 761115 + orf19.1323 758495 761115 1 758495 761115 758543 760858 orf19.8903|IPF26010.1|IPF12906.2|Contig4-2436_0008|orf6.4885|CA2826|APL6|CaO19.1323|CaO19.8903 Phosphorylated protein of unknown function; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 762939 764843 + orf19.1321 762939 764843 1 762939 764843 762939 764843 HWP1 orf19.8901|ECE2|IPF26012.1|IPF12916.1|Contig4-2436_0002|orf6.4883|CA2825|CaO19.8901|CaO19.1321 Hyphal cell wall protein; covalently crosslinked to epithelial cells by host transglutaminase; opaque- and a-specific, alpha-factor induced; at MTLa side of conjugation tube; assessment of virulence role complicated by URA3 effects [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 765587 767013 + orf19.1318 765587 767013 1 765587 767013 765747 766820 orf19.8898|IPF26020.1|IPF17888.2|Contig4-1592_0002|orf6.4880|CA2824|CaO19.8898|CaO19.1318|IPF17888 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 766846 769762 - orf19.1317 766846 769762 1 769762 766846 769486 766952 OSH3 orf19.8897|IPF26009.1|IPF14554.2|Contig4-1592_0001|orf6.4879|CA2823|CaO19.8897|CaO19.1317|IPF14554 Protein required for wild-type filamentation; has oxysterol binding protein domain and pleckstrin homology motif; overproducton suppresses cph1 homozygous null filamnetation defect; similar to S. cerevisiae Osh3p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 770497 772185 - orf19.1314 770497 772185 1 772185 770497 772087 770678 orf19.8894|IPF26016.1|IPF17153.2|orf6.4876|CA2822|CaO19.1314|CaO19.8894|IPF14550 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 772498 772584 - tq(uug)1 772498 772584 2 772584|772532 772547|772498 tQ(UUG)1.2 tRNA-Gln predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 772891 774424 - orf19.1313 772891 774424 1 774424 772891 774255 773035 CDR3 orf19.8892|orf19.8893|IPF26026.1|IPF14709.3|YPL088-1|Contig4-1792_0002|orf6.3101|orf6.4875|CA1545|orf19.1312|CaO19.1312|CaO19.8892|CA2821|CDR3.3eoc|IPF17152.1|CDR3.5eoc|IPF14709.2 Transporter of the Pdrp/Cdrp family of the ATP-binding cassette (ABC) superfamily; transports phospholipids in an out-to-in direction; expressed in opaque-phase cells; induced by macrophage interaction; fluconazole-downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 774199 777540 - ntar_782 774199 777540 1 777540 774199 777540 774199 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 780305 780375 - tg(gcc)2 780305 780375 1 780375 780305 tG(GCC)2.2 tRNA-Gly predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 780604 780840 - ntar_783 780604 780840 1 780840 780604 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 781047 781118 - td(guc)4 781047 781118 1 781118 781047 tD(GUC)4.2 tRNA-Asp predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 781665 782025 + ntar_1419 781665 782025 2 781665|781874 781741|782025 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 782574 782645 + td(guc)3 782574 782645 1 782574 782645 tD(GUC)3.2 tRNA-Asp predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 782729 782800 + td(guc)2 782729 782800 1 782729 782800 tD(GUC)2.2 tRNA-Asp predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 782925 785510 + orf19.1311 782925 785510 1 782925 785510 782925 785510 SPO75 orf19.8891|IPF6671.2|IPF29492.1|Contig4-2805_0006|orf6.3102|CA1546|CaO19.8891|CaO19.1311|IPF6671 Similar to S. cerevisiae sporulation protein; fungal-specific (no human or murine homolog) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 783229 787235 - orf19.1310 783229 787235 1 787235 783229 787132 785501 orf19.8890|IPF6672.2|IPF18706.2|orf6.2770|orf6.3103|CA1547|IPF6672|CaO19.1310 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 787446 788084 - orf19.1309 787446 788084 1 788084 787446 787968 787555 orf19.8889|IPF6673.1|IPF6675.2|Contig4-2324_0006|orf6.2771|orf6.3104|CA1323|CaO19.1309|IPF6675 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 788639 790500 + orf19.1308 788639 790500 1 788639 790500 788714 790459 orf19.8888|IPF18658.2|IPF6676.2|Contig4-2324_0003|orf6.2772|orf6.3105|CA1324|FNX1|CaO19.1308|IPF6676 Predicted membrane transporter, member of the drug:proton antiporter (14 spanner) (DHA2) family, major facilitator superfamily (MFS) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 790464 792113 - orf19.1307 790464 792113 1 792113 790464 792025 790523 orf19.8887|IPF26015.1|IPF6678.2|Contig4-2324_0002|orf6.2773|CA1325|CaO19.1307|CaO19.8887|IPF6678 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr4 792459 793685 - orf19.1306 792459 793685 1 793685 792459 793553 792534 orf19.8886|IPF26019.1|IPF6679.1|orf6.2774|CA1326|CaO19.8886|CaO19.1306|IPF6679 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr4 793939 795535 - orf19.1305 793939 795535 1 795535 793939 795504 794101 orf19.8885|IPF26017.1|IPF6680.2|Contig4-1569_0002|Contig4-2781_0001|orf6.2775|CA1327|CaO19.1305|CaO19.8885|IPF6680 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr4 795584 796719 + orf19.1304 795584 796719 1 795584 796719 795663 796577 orf19.8884|IPF6681.3|IPF6682.2|Contig4-2781_0003|orf6.2776|CA1328|RRP4|CaO19.8884|CaO19.1304 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 796666 797958 - orf19.1303 796666 797958 1 797958 796666 797872 796688 orf19.8883|IPF19627.2|IPF19626.1|Contig4-2781_0004|Contig4-2781_0005|Contig4-2781_0008|orf6.1384|orf6.2777|CA1329|CaO19.1303|MRF1|MRF2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 798828 799478 + orf19.1302 798828 799478 1 798828 799478 798828 799478 orf19.8882|IPF13556.2|IPF29496.1|Contig4-2781_0010|orf6.1385|orf6.2778|CA0451|CaO19.1302|IPF13556 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 800045 800835 + orf19.1301 800045 800835 1 800045 800835 800217 800711 orf19.8881|IPF13554.1|IPF18704.2|Contig4-2781_0016|orf6.1386|CA0452|CaO19.1301|IPF13554 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 800677 802210 - orf19.1300 800677 802210 1 802210 800677 802162 800828 orf19.8880|IPF13552.2|IPF29494.1|Contig4-2781_0017|orf6.1387|CA0453|CaO19.1300|IPF13552 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 802385 803927 + orf19.1299 802385 803927 1 802385 803927 802437 803744 RPN6 orf19.8879|IPF13551.2|IPF29495.1|Contig4-2781_0018|orf6.1388|CA0454|CaO19.1299 Predicted ORF in Assemblies 19, 20 and 21; regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 803711 806440 - orf19.1298 803711 806440 1 806440 803711 806316 803782 orf19.8878|IPF26014.1|IPF16027.3|Contig4-2781_0019|Contig4-2781_0020|Contig4-2781_0021|orf6.1389|orf6.923|CA0225|NUP84|CaO19.1298|IPF16027.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 807141 809647 + orf19.1297 807141 809647 1 807141 809647 807452 809647 orf19.12503|orf19.8877|IPF26018.1|IPF16024.1|IPF22191.1|IPF17055.1|Contig4-2781_0024|orf6.924|orf6.3313|CA0226|CA1692|orf19.5036|ATG20|CaO19.1297|CaO19.8877|IPF16024 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chr4 809695 810963 - orf19.5037 809695 810963 1 810963 809695 810963 809695 orf19.12504|IPF17054|IPF22188.1|IPF17054.2|orf6.3314|CA1693|CaO19.12504|HRQ2|CaO19.5037 Protein not essential for viability [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr4 812021 816520 + orf19.5038 812021 816520 1 812021 816520 812074 816396 orf19.12505|IPF22196.1|IPF12305.2|orf6.3315|CA1694|TRM3|CaO19.12505|CaO19.5038 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr4 816364 817557 - orf19.5039 816364 817557 1 817557 816364 817481 816489 orf19.12506|IPF22190.1|IPF12306.1|Contig4-2272_0001|Contig4-2272_0002|orf6.3316|CA1695|RRP42|CaO19.12506|CaO19.5039 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr4 817510 817759 + ntar_784 817510 817759 1 817510 817759 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 817920 819946 + orf19.5040 817920 819946 1 817920 819946 818048 819826 orf19.12507|IPF22186.1|IPF12310.2|Contig4-2272_0003|orf6.3317|CA1696|ASM4|CaO19.12507|CaO19.5040 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 819824 821191 - orf19.5041 819824 821191 1 821191 819824 821011 819938 orf19.12508|IPF22189.1|IPF19742.1|Contig4-2272_0004|orf6.3318|CA6218|CaO19.5041|CaO19.12508|IPF19742 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr4 821221 822020 - orf19.5042 821221 822020 1 822020 821221 821859 821221 orf19.12509|IPF22193.1|IPF16759.2|Contig4-2272_0004|orf6.3319|CaO19.12509|CaO19.5042 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr4 822057 824009 + orf19.5043 822057 824009 1 822057 824009 822239 823705 orf19.12510|IPF17702.3|IPF16758.1|Contig4-1448_0002|Contig4-2272_0007|Contig4-2272_0008|orf6.3320|orf6.429|CA1697|CaO19.5043|IPF16758 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 826068 828471 + orf19.5045 826068 828471 1 826068 828471 826204 828471 orf19.12512|IPF22192.1|IPF19279.2|IPF18627.1|IPF15681.2|Contig4-2568_0005|orf6.3322|orf6.427|CA1698|IPF15681 Predicted ORF in Assemblies 19, 20 and 21; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chr4 826947 827945 - ntar_785 826947 827945 1 827945 826947 827201 827007 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 828049 828351 - ntar_786 828049 828351 1 828351 828049 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 828509 830613 - orf19.5046 828509 830613 1 830613 828509 830511 828754 RAM1 orf19.12513|IPF22187.1|IPF19534.2|Contig4-2773_0012|orf6.3323|CA1700|CaO19.5046|RAM1.5f|CA1699|RAM1.3f|IPF19535.1|IPF19534.1 Protein that acts in prenylation; transcription is alpha-factor induced; regulated in response to lovastatin and fluconazole [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 830961 831208 + ntar_787 830961 831208 1 830961 831208 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 832143 834601 + orf19.1596 832143 834601 1 832143 834601 832702 834546 FGR28 orf19.9164|IPF17205.1|IPF15031.1|Contig4-1965_0001|Contig4-1965_0002|orf6.1082|orf6.426|CA0296|CaO19.1596|LPF17|IFA11|CA0075|IFA24.3 Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr4 834971 836922 + orf19.1595 834971 836922 1 834971 836922 835182 836888 orf19.9163|IPF25734.1|IPF15033.2|Contig4-1965_0005|orf6.1081|CA0295|IPF15033.5eoc|IPF15033 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr4 836438 837530 - orf19.789.1 836438 837530 1 837530 836438 837428 836988 Predicted ORF in Assembly 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 837669 841438 - orf19.789 837669 841438 1 841438 837669 841339 837806 PYC2 orf19.8408|orf6.2989|IPF26382.1|IPF26504.1|IPF15163.2|IPF15167.2|Contig4-3027_0007|CA1464|PYC2.3f|PYC2.exon2 Putative pyruvate carboxylase, binds to biotin cofactor; up-regulated in mutant lacking the Ssk1p response regulator protein, upon benomyl treatment, or in an azole-resistant strain overexpressing MDR1 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 842699 843102 + ntar_788 842699 843102 1 842699 843102 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 843434 845401 + ntar_789 843434 845401 1 843434 845401 844524 844694 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 844616 844921 - orf19.787 844616 844921 1 844921 844616 844921 844616 orf19.8406|IPF26483.1|IPF29675.1|orf6.558|CaO19.787|CaO19.8406 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 845625 846355 + orf19.787.1 845625 846355 1 845625 846355 845676 845891 CA1463|PYC2.5f ORF added to Assembly 21 based on comparative genome analysis; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 847295 847627 + orf19.1207 847295 847627 1 847295 847627 847295 847627 IPF27537.1|Contig4-2606_0009|orf6.840|CaO19.1207 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 849772 850833 - orf19.1208 849772 850833 1 850833 849772 850833 849772 IPF19849.1|Contig4-3026_0002|orf6.841 Predicted ORF in Assemblies 19, 20 and 21; member of a family encoded by FGR6-related genes in the RB2 repeat sequence [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 851957 852110 + ntar_790 851957 852110 1 851957 852110 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 852786 852962 + ntar_791 852786 852962 1 852786 852962 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 853775 855494 + orf19.5312 853775 855494 1 853775 855494 854134 855291 orf19.12772|IPF21855.1|IPF8210.1|Contig4-2503_0001|orf6.8301|CA5480|CaO19.12772|CaO19.5312|IPF8210 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 858470 861320 + orf19.5311 858470 861320 1 858470 861320 858597 861125 orf19.12771|IPF21821.1|IPF8205.1|Contig4-2503_0005|Contig4-2961_0001|Contig4-2961_0031|orf6.8300|CA5479|CaO19.5311|CaO19.12771|IPF8205 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr4 861382 861810 - orf19.5308 861382 861810 1 861810 861382 861810 861382 orf19.12768|IPF21894.1|IPF8200.1|Contig4-2961_0002|orf6.8297|CaO19.12768|CaO19.5308 Predicted ORF in Assemblies 19, 20 and 21; induced by Rgt1p [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 864683 866572 + orf19.5307 864683 866572 1 864683 866572 864845 866386 JEN2 orf19.12767|IPF8196.1|IPF8525.2|Contig4-2961_0006|orf6.8296|orf6.991|CA5478|CaO19.5307 Protein described as carboxylic acid transporter; induced by Rgt1p; transcription is upregulated in both intermediate and mature biofilms [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 866890 867306 + orf19.5306 866890 867306 1 866890 867306 866890 867306 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 867608 868461 - orf19.5305 867608 868461 1 868461 867608 868407 867793 RHD3 orf19.12765|orf6.8294|PGA29|IPF21875.1|IPF8527.1|Contig4-2961_0009|CA5476|LDG7|CaO19.12765|CaO19.5305|IPF8527 GPI-anchored cell wall protein; transcription is decreased upon yeast-hyphal switch; transcriptionally regulated by iron; expression greater in high iron; clade-associated gene expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 869238 869603 + orf19.5304 869238 869603 1 869238 869603 869238 869603 orf19.12764|IPF21881.1|IPF8528.1|Contig4-2961_0010|orf6.8293|CaO19.5304|CaO19.12764 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 871177 872010 - orf19.5303 871177 872010 1 872010 871177 872010 871177 PGA30 orf19.12763|IPF21868.1|IPF8532.2|Contig4-2961_0012|orf6.8292|CA5475|CaO19.5303|LDG6|CaO19.12763|IPF8532 Putative GPI-anchored protein of cell wall [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 874083 875200 - orf19.5302 874083 875200 1 875200 874083 875200 874142 PGA31 orf19.12761|IPF21866.1|IPF8535.2|Contig4-2961_0018|orf6.3932|orf6.8290|CA2156|CaO19.5302|LDG5|IPF8535 Cell wall protein; putative GPI anchor; expression is regulated upon white-opaque switching; induced during cell wall regeneration; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr4 876658 878699 - orf19.5300 876658 878699 1 878699 876658 878564 876819 orf19.12759|IPF18102.2|IPF8537.2|Contig4-2961_0019|Contig4-2961_0020|Contig4-2961_0021|orf6.3934|orf6.8288|CA2157|CNE1|CaO19.5300|IPF8537 Predicted ORF in Assemblies 19, 20 and 21; caspofungin induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 878713 879591 - orf19.5299 878713 879591 1 879591 878713 879516 878923 ECM1 orf19.12758|IPF21887.1|IPF8538.2|Contig4-2961_0022|orf6.3935|CA2158|CaO19.5299 Decreased mRNA abundance observed in cyr1 homozygous mutant hyphae; induced by heavy metal (cadmium) stress; Hog1p regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 879814 880769 + ntar_792 879814 880769 1 879814 880769 880332 880580 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 880630 882950 - orf19.5297 880630 882950 1 882950 880630 882641 880749 orf19.12756|IPF21837.1|IPF19753.1|Contig4-2961_0028|Contig4-2961_0029|orf6.3937|CA2159|TFB1|CaO19.12756|CaO19.5297|IPF19753 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 882980 883810 + orf19.5296 882980 883810 1 882980 883810 882980 883642 orf19.12755|IPF21874.1|IPF15664.2|orf6.3938|CA2160|FMP35|CaO19.12755|CaO19.5296|IPF15664 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr4 884117 885406 + orf19.5295 884117 885406 1 884117 885406 884228 885319 orf19.12754|IPF21854.1|IPF11876.2|Contig4-2497_0007|orf6.3939|CA2161|CaO19.12754|EEP1|CaO19.5295|IPF11876 Predicted ORF in Assemblies 19, 20 and 21; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 885407 886782 - orf19.5294 885407 886782 1 886782 885407 886701 885562 PDB1 orf19.12753|IPF21857.1|IPF11877.2|Contig4-2497_0006|orf6.3940|CA2162|CaO19.12753|CaO19.5294 Protein described as similar to pyruvate dehydrogenase; fluconazole-induced; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 886922 887295 - ntar_793 886922 887295 1 887295 886922 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 887766 888075 - ntar_794 887766 888075 1 888075 887766 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 888164 890078 + orf19.5293 888164 890078 1 888164 890078 888375 889898 orf19.12751|IPF19472.2|IPF11879.2|Contig4-2497_0003|Contig4-2497_0004|orf6.35|orf6.3941|CA2163|ACT2|CaO19.5293|CaO19.12751|IPF11879 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 889963 893592 - orf19.5292 889963 893592 1 893592 889963 893236 890369 AXL2 orf19.12750|IPF21817.1|IPF11881.2|Contig4-2497_0002|orf6.3942|CA2164|CaO19.12750|CaO19.5292 Protein not essential for viability; similar to S. cerevisiae Axl2p, which is a plasma membrane protein involved in determination of budding pattern; O-glycosylated by Pmt4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr4 893809 894407 - ntar_795 893809 894407 1 894407 893809 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 895700 896857 - orf19.5291 895700 896857 1 896857 895700 896778 895777 orf19.12749|IPF21862.1|IPF17024.2|Contig4-2598_0011|orf6.3943|CA2165|CaO19.5291|SCS3|CaO19.12749|IPF17024 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr4 897063 898541 - orf19.5290 897063 898541 1 898541 897063 898541 897198 orf19.12748|orf6.3944|IPF21848.1|IPF17022.3|CaO19.5290|CaO19.12748 Transcription is negatively regulated by Sfu1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 897198 899857 - orf19.1430 897198 899857 1 899857 897198 899744 897198 orf19.12773|orf19.9006|IPF25911.1|IPF9379.3|IPF19810.1|IPF28064.1|Contig4-2598_0008|Contig4-2598_0009|orf6.6399|orf6.8302|CA3969|CA5481|orf19.5313|IPF9379.5eoc|IPF9379|IPF9379.2 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 898558 898998 + ntar_796 898558 898998 1 898558 898998 898873 898998 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 900902 901842 - orf19.1429 900902 901842 1 901842 900902 901810 901370 SOH1 orf19.9005|IPF25919.1|IPF9378.1|Contig4-2598_0004|orf6.6398|CA3968|CaO19.9005|CaO19.1429|IPF9378 Predicted ORF in Assemblies 19, 20 and 21; cell-cycle regulated periodic mRNA expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 902114 902766 + orf19.1428 902114 902766 1 902114 902766 902219 902734 orf19.9004|IPF25920.1|IPF9377.1|Contig4-2598_0002|orf6.6397|CA3967|CaO19.1428|CaO19.9004|IPF9377 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 903172 904755 + orf19.1427 903172 904755 1 903172 904755 903172 904668 orf19.9003|IPF25909.1|IPF9376.1|Contig4-2598_0001|orf6.6396|CA3966|CaO19.1427|CaO19.9003|IPF9376 Putative transporter; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 904672 907402 - orf19.1426 904672 907402 1 907402 904672 907123 904994 orf19.9002|IPF25901.1|IPF9375.2|orf6.6395|CA3965|CaO19.9002|CaO19.1426|IPF9375 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 908871 910729 + orf19.1424 908871 910729 1 908871 910729 908945 910660 orf19.9000|IPF25904.1|IPF9370.2|Contig4-2191_0005|orf6.6393|CA3964|CaO19.1424|CaO19.9000|IPF9370 Predicted membrane transporter, member of the oxalate:formate antiporter (OFA) family, major facilitator superfamily (MFS) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 910583 913636 - orf19.1422 910583 913636 1 913636 910583 913422 910798 FZO1 orf19.8998|IPF25897.1|IPF11233.2|Contig4-2191_0006|orf6.6391|CA3963|CaO19.8998|CaO19.1422|IPF11233 Putative mitochondrial biogenesis protein; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 913795 914508 + orf19.1421 913795 914508 1 913795 914508 913834 914475 orf19.8997|IPF25916.1|IPF11234.1|Contig4-2563_0012|orf6.6390|CA3962|DAL3|CaO19.8997|CaO19.1421|IPF11234 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 914285 915358 - orf19.1420 914285 915358 1 915358 914285 915330 914503 orf19.8996|IPF25912.1|IPF11235.2|Contig4-2563_0010|Contig4-2563_0011|orf6.6389|CA3961|CaO19.1420|CaO19.8996|IPF11235 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 915451 918327 + orf19.1418 915451 918327 1 915451 918327 915503 918181 SEC15 orf19.8994|orf19.8995|IPF25910.1|IPF11238.2|Contig4-2563_0007|Contig4-2563_0009|orf6.6387|orf6.6388|CA3959|CA3960|orf19.1419|CaO19.8994|CaO19.1418|IPF11236.3f Predicted exocyst subunit; ortholog of S. cerevisiae SEC15 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 917889 918753 - orf19.1417 917889 918753 1 918753 917889 918582 918247 orf19.8993|IPF25924.1|IPF11239.1|Contig4-2563_0006|orf6.6386|CaO19.1417|FMP14|CaO19.8993 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 918783 919942 + orf19.1416 918783 919942 1 918783 919942 918818 919639 COX11 orf19.8992|IPF25913.1|IPF11240.1|Contig4-2563_0004|Contig4-2563_0005|orf6.6385|CA3958|CaO19.1416|CaO19.8992 Protein repressed during the mating process; transcription is regulated by Nrg1p; transcription is upregulated in both intermediate and mature biofilms [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 919273 919570 - ntar_797 919273 919570 1 919570 919273 919570 919385 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 922889 925506 + orf19.1415 922889 925506 1 922889 925506 923142 925262 FRE10 orf19.8991|CFL95|FRE1|RBT2|IPF25902.1|IPF6709.2|Contig4-2963_0017|orf6.6384|CA3957|CaO19.1415|CaO19.8991 Major cell-surface ferric reductase under low-iron conditions; 7 transmembrane regions and a secretion signal predicted; repressed by Tup1p, Rim101p, Ssn6p, Hog1p, caspofungin; ciclopirox olamine induced; not required for filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 925591 926868 - orf19.1414 925591 926868 1 926868 925591 926702 925797 orf19.8990|IPF25914.1|IPF6712.1|Contig4-2963_0013|orf6.6383|CA3955|WWM1|CaO19.1414|CaO19.8990|IPF6712.5f Putative protein of unknown function, transcription is upregulated in an RHE model of oral candidiasis; predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 927182 928043 - orf19.1413 927182 928043 1 928043 927182 927958 927425 YFH1 orf19.8989|orf6.6382|IPF25917.1|IPF6713.2|Contig4-2963_0011|CA3954|CaO19.1413|CaO19.8989 Frataxin; homolog of S. cerevisiae Yfh1p, mammalian frataxin; may be required for iron storage or delivery; role in oxidative stress resistance; transcription regulated by Nrg1p, repressed if iron absent, induced by macrophage interaction [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 928190 929025 + orf19.1412 928190 929025 1 928190 929025 928190 928822 orf19.8988|IPF25915.1|IPF6714.2|Contig4-2963_0009|orf6.6381|CA3953|CaO19.8988|CaO19.1412|IPF6714 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr4 929121 930928 + orf19.1411 929121 930928 1 929121 930928 929121 930923 orf19.8987|IPF25905.1|IPF6716.1|Contig4-2963_0008|orf6.6380|CA3952|CaO19.8987|PAH1|CaO19.1411|IPF6716 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr4 930904 933515 - orf19.1409 930904 933515 1 933515 930904 933438 931099 VAC7 orf19.8985|IPF25899.1|IPF6717.2|Contig4-2963_0006|orf6.6378|VAC7.3|CA3951|CaO19.8985|CaO19.1409 Protein not essential for viability; similar to S. cerevisiae Fab1p, which is an enzyme regulator involved in phospholipid metabolism [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 934624 935514 - orf19.1409.2 934624 935514 1 935514 934624 935405 935121 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 936876 938102 + orf19.1409.1 936876 938102 2 936876|937517 936944|938102 936933 937879 Predicted ORF in Assembly 20 and 21; gene has intron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 940387 940662 - orf19.1409.3 940387 940662 1 940662 940387 940662 940387 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 940637 941143 - ntar_798 940637 941143 1 941143 940637 940816 940637 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 944068 946400 - orf19.3846 944068 946400 1 946400 944068 946259 944205 LYS4 orf19.11327|IPF23444.1|IPF4077.2|Contig4-3060_0033|orf6.7541|CA4869|CaO19.11327|CaO19.3846 Protein described as homoaconitase; regulated by Gcn4p, Gcn2p; induced in response to amino acid starvation (3-aminotriazole treatment); upregulated in the presence of human whole blood or polymorphonuclear (PMN) cells [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 947588 949334 + orf19.3845 947588 949334 1 947588 949334 947694 949217 FGR3 orf19.11326|IPF23458.1|IPF4078.1|Contig4-3060_0032|orf6.7540|CA4868|CaO19.11326|CaO19.3845|IPF4078 Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 948455 949381 - ntar_799 948455 949381 1 949381 948455 949172 948966 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 949452 950218 + orf19.3844 949452 950218 1 949452 950218 949500 950117 MRP8 orf19.11325|IPF23479.1|IPF4080.1|Contig4-3060_0029|orf6.7539|CA4867|CaO19.11325|CaO19.3844|IPF4080 Protein not essential for viability; similar to S. cerevisiae Mrp8p, which is a mitochondrial ribosomal protein; greater transcription in hyphal form than yeast form [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 950346 951322 + orf19.3843 950346 951322 1 950346 951322 950420 951226 orf19.11324|IPF23471.1|IPF4083.1|Contig4-3060_0028|orf6.7538|CA4866|CaO19.11324|SEC66|CaO19.3843|IPF4083 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 951289 954061 - orf19.3841 951289 954061 1 954061 951289 953871 951367 orf19.11322|IPF4085|IPF23437.1|IPF4085.1|Contig4-3060_0026|orf6.7536|CA4865|CaO19.3841|ATG1|CaO19.11322 Predicted ORF in Assemblies 19, 20 and 21; described as similar to S. cerevisiae Apg1p; induced upon adherence to polystyrene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr4 954639 959113 - orf19.3840 954639 959113 1 959113 954639 959014 954788 orf19.11321|IPF23489.1|IPF4087.1|Contig4-3060_0022|orf6.7535|CA4864|CaO19.11321|CaO19.3840|IPF4087 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 960963 962375 + orf19.3839 960963 962375 1 960963 962375 961014 962375 SAP10 orf19.11320|orf6.7534|IPF23460.1|IPF4089.1|Contig4-3060_0016|CA4863|YPS3|CaO19.11320|CaO19.3839|IPF4089 Secreted aspartyl proteinase; roles in adhesion, virulence (RHE model), cell surface integrity; distinct specificity from Sap9p; at cell membrane and wall; GPI-anchored; N-glycosylated; expression greater in low iron; Tbf1p-activated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr4 962342 963933 - orf19.3838 962342 963933 2 963933|963324 963690|962342 963769 962763 EFB1 orf19.11319|IPF23480.1|IPF4091.1|Contig4-3060_0012|orf6.7533|CA4862 Translation elongation factor EF-1 beta; downregulated in the presence of human whole blood or polymorphonuclear cells; macrophage/pseudohyphal-induced; antigenic in mouse; functional homolog of S. cerevisiae Efb1p; farnesol-downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 964082 964988 - orf19.3836 964082 964988 1 964988 964082 964922 964170 orf19.11317|IPF23468.1|IPF4094.1|Contig4-3060_0009|orf6.7531|CA4861|CaO19.11317|CaO19.3836|IPF4094 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 965061 969451 + orf19.3833 965061 969451 1 965061 969451 965204 969403 orf19.11314|orf19.11316|IPF23441.1|IPF23449.1|IPF15927.2|IPF19804.1|IPF15927.5f|Contig4-3060_0003|Contig4-3060_0005|orf6.7528|orf6.7530|CA4859|CA4860|orf19.3835 Putative DNA-binding transcription factor; decreased transcription is observed upon fluphenazine treatment [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 969567 970567 + orf19.3831 969567 970567 1 969567 970567 969601 970431 orf19.11312|IPF15931.3|IPF15929.1|Contig4-3060_0002|orf6.7526|CA4858|CaO19.11312|CaO19.3831|IPF15927.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 970529 972261 - orf19.3829 970529 972261 1 972261 970529 972261 970615 PHR1 orf19.11310|orf6.7524|IPF23455.1|IPF15932.2|Contig4-2187_0001|Contig4-3060_0001|CA4857|CaO19.3829|CaO19.11310 Glycosidase of cell surface; may act on cell-wall beta-1,3-glucan prior to beta-1,6-glucan linkage; E169 and E270 at active site; role in systemic but not vaginal virulence (neutral, not low pH); high pH or filamentation induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr4 972397 972648 - ntar_800 972397 972648 1 972648 972397 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 973277 973609 - orf19.3828 973277 973609 1 973609 973277 973609 973277 orf19.11309|IPF23487.1|IPF20174.1|orf6.7523|CaO19.11309|CaO19.3828 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 974393 975700 - orf19.3827 974393 975700 1 975700 974393 975579 974569 orf19.11308|IPF23465.1|IPF15950.2|Contig4-2187_0004|Contig4-2187_0006|orf6.7522|CA4856|CaO19.11308|CaO19.3827|IPF15950 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 976457 977739 - orf19.3826 976457 977739 1 977739 976457 977449 976601 orf19.11307|IPF23472.1|IPF5830.2|Contig4-2989_0002|orf6.7521|CA4855|CaO19.11307|CaO19.3826|IPF5830 Predicted ORF in Assemblies 19, 20 and 21; Plc1p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 978107 978490 - ntar_801 978107 978490 1 978490 978107 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 979346 980368 + orf19.3825 979346 980368 1 979346 980368 979399 980244 RCE1 orf19.11306|IPF23473.1|IPF5825.1|Contig4-2989_0006|orf6.7520|CA4854|CaO19.11306|CaO19.3825 Protein induced during the mating process [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 982083 987318 + orf19.3823 982083 987318 1 982083 987318 982303 987240 ZDS1 orf19.11304|CES1|IPF23484.1|IPF5823.2|Contig4-2989_0013|orf6.7518|CA4853|IPF5823 Nonessential protein; similar to S. cerevisiae Zds1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 987658 989236 + orf19.3822 987658 989236 1 987658 989236 987869 989005 SCS7 orf19.11303|orf6.7517|IPF23462.1|IPF5819.1|Contig4-2989_0014|CA4852|CaO19.3822|CaO19.11303 Protein described as ceramide hydroxylase; transcription is regulated by Nrg1p; transcriptionally regulated by iron; expression greater in high iron; fluconazole-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 989142 990554 - orf19.3821 989142 990554 1 990554 989142 990508 989321 orf19.11302|IPF23461.1|IPF5818.1|Contig4-2989_0015|orf6.7516|CA4851|CaO19.11302|CaO19.3821|IPF5818 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 996165 997715 - orf19.3820 996165 997715 1 997715 996165 997715 996165 orf19.11301|IPF23456.1|IPF3257.2|Contig4-3009_0010|orf6.1534|orf6.7515|orf6.1854|CA4850|CTN2|CaO19.3820|CaO19.11301|Cirt2 Predicted ORF in Assemblies 19, 20 and 21; clade-associated gene expression [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 998850 999245 - orf19.3819 998850 999245 1 999245 998850 999245 998880 orf19.11300|IPF23488.1|IPF28641.1|Contig4-2979_0001|orf6.7514|CaO19.11300|CaO19.3819 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 999262 1000334 - orf19.3818 999262 1000334 1 1000334 999262 1000098 999262 GOA1 orf19.11299|orf6.7513|IPF6954|IPF23470.1|IPF6954.1|Contig4-2979_0002|CA4849|CaO19.3818|CaO19.11299 Protein required for respiratory growth, resistance to oxidants, chlamydospore formation, hyphal growth under some conditions, and virulence; relocalizes from the cytoplasm to the mitochondrion during oxidative or osmotic stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1000452 1001443 + orf19.3817 1000452 1001443 1 1000452 1001443 1000608 1001327 orf19.11298|IPF23476.1|IPF6953.1|Contig4-2979_0004|orf6.7512|CA4848|CaO19.11298|RTS2|CaO19.3817 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1001277 1004444 - orf19.3815 1001277 1004444 1 1004444 1001277 1004278 1001429 orf19.11296|IPF23429.1|IPF6951.2|Contig4-2979_0005|Contig4-2979_0008|orf6.7510|CA4847|CaO19.3815|UBP7|CaO19.11296|IPF6951 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1005004 1006645 - orf19.3813 1005004 1006645 1 1006645 1005004 1006645 1005143 orf19.11294|orf19.11295|IPF23481.1|IPF23467.1|IPF6946.2|IPF6945.2|Contig4-2979_0010|Contig4-2979_0011|orf6.7508|orf6.7509|CA4845|CA4846|orf19.3814|IPF6945.5f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr4 1006771 1006856 - tq(uug)5 1006771 1006856 2 1006856|1006805 1006819|1006771 tQ(UUG)5.2 tRNA-Gln predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 1006867 1006949 - tq(uug)4 1006867 1006949 2 1006949|1006901 1006912|1006867 tQ(UUG)4.2 tRNA-Gln predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 1007627 1009352 + orf19.3812 1007627 1009352 1 1007627 1009352 1007666 1009288 SSZ1 orf19.11293|IPF23457.1|IPF6943.1|Contig4-2979_0013|orf6.7507|CA4844|PDR13|CaO19.11293|CaO19.3812 Protein described as an HSP70 chaperone; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1009575 1011542 + orf19.3811 1009575 1011542 1 1009575 1011542 1009631 1011325 GYP1 orf19.11292|IPF23453.1|IPF6940.2|Contig4-2979_0016|orf6.7506|CA4843|CaO19.11292|CaO19.3811 Transcription is regulated by Nrg1p, Mig1p, and Tup1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1011708 1012809 + orf19.3810 1011708 1012809 1 1011708 1012809 1011783 1012754 orf19.11291|IPF23466.1|IPF6938.2|Contig4-2979_0018|orf6.7505|CA4842|CaO19.3810|MTD1|CaO19.11291 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1013121 1015417 + orf19.3809 1013121 1015417 1 1013121 1015417 1013121 1015337 FIL1|orf19.11290|IPF23442.1|IPF10355.2|Contig4-2979_0019|orf6.1870|orf6.7504|CA4841|BAS1|CaO19.11290|CaO19.3809|IPF10355 Putative transcription factor with Myb-like DNA-binding motif; similar to S. cerevisiae Bas1p, which is a regulator of purine biosynthetic genes; ADE genes are not induced during GCN response in C. albicans, in contrast to S. cerevisiae [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1015529 1015615 + ti(aau)4 1015529 1015615 2 1015529|1015580 1015566|1015615 tI(AAU)4.2 tRNA-Ile predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 1015784 1017677 + orf19.3806 1015784 1017677 1 1015784 1017677 1015974 1017470 orf19.11287|IPF10359.2|IPF19367.2|Contig4-2432_0005|orf6.1869|orf6.261|CA0753|CaO19.3806|IPF10359 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1017454 1018506 - orf19.3804 1017454 1018506 1 1018506 1017454 1018439 1017672 orf19.11285|IPF23475.1|IPF10360.2|Contig4-2432_0004|orf6.1867|orf6.263|CA0041|CaO19.3804|IPF10360 Predicted ORF in Assemblies 19, 20 and 21; filament induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1018712 1020679 - orf19.3803 1018712 1020679 1 1020679 1018712 1020660 1018891 MNN22 orf19.11284|IPF10363.2|IPF10361.3|Contig4-2432_0003|orf6.1866|orf6.264|CA0752|MNN24|CaO19.3803 Protein described as similar to Golgi alpha-1,2-mannosyltransferase; regulated by Tsa1p, Tsa1Bp in minimal media at 37 deg; Hog1p-induced; induced by nitric oxide; downregulated in core stress response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1018718 1020257 + ntar_802 1018718 1020257 1 1018718 1020257 1018974 1019123 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1022492 1025381 + orf19.3802 1022492 1025381 1 1022492 1025381 1022690 1025188 PMT6 orf19.11283|PMT3|IPF10365.3|IPF9088.2|Contig4-2789_0009|orf6.1474|orf6.1865|CA0503|CaO19.3802 Protein mannosyltransferase, required for virulence in mouse systemic infection and for adhesion to endothelium; has a role in hyphal growth signaling and hygromycin B sensitivity; not a major contributor to overall cellular PMT activity [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1027634 1030180 + orf19.3801 1027634 1030180 1 1027634 1030180 1027634 1030180 FAV1 orf19.11282|IPF9090.2|IPF28628.1|Contig4-2789_0005|Contig4-3100_0023|orf6.201|orf6.2919|CA1424|CaO19.3801|IPF9090 Protein with weak similarity to S. cerevisiae Fus2p; induced by alpha pheromone mating factor in MTLa/MTLa opaque cells [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 1033188 1034860 + orf19.3799 1033188 1034860 1 1033188 1034860 1033344 1034444 orf19.11280|IPF23463.1|IPF14247.2|Contig4-3100_0004|orf6.2917|CA1423|CaO19.3799|RTN1|CaO19.11280|IPF14247 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1034800 1036015 - orf19.3798 1034800 1036015 1 1036015 1034800 1035964 1034894 orf19.11279|IPF23464.1|IPF14248.2|Contig4-3100_0008|orf6.2916|CA1422|CaO19.3798|TRM8|CaO19.11279|IPF14248 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1036081 1037149 - orf19.3797 1036081 1037149 1 1037149 1036081 1037061 1036285 orf19.11278|IPF14249.2|IPF6901.3|Contig4-2569_0002|orf6.2915|orf6.3070|CA1421|MRPL11|CaO19.3797 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1037319 1039455 + orf19.3796 1037319 1039455 1 1037319 1039455 1037525 1039360 orf19.11277|IPF14250.2|IPF6904.1|Contig4-2569_0003|Contig4-2569_0004|orf6.2914|orf6.3069|CA1420|RNT1|CaO19.3796 Putative Dicer RNAse involved in RNA interference, similar to S. cerevisiae Rnt1p but orthologous to S. castellii Dcr1p, which is not conserved in S. cerevisiae; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1039478 1041319 - orf19.3795 1039478 1041319 1 1041319 1039478 1041176 1039635 AGP3 orf19.11275|IPF23454.1|IPF6906.1|Contig4-2569_0006|orf6.3068|CA1525|CaO19.3795 Putative serine transporter with possible role in assimilation of sulfur; induced upon early biofilm formation; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1042100 1044596 - orf19.3794 1042100 1044596 1 1044596 1042100 1044409 1042268 CSR1 orf19.11274|SUR1|ZAP1|IPF23443.1|IPF6909.2|Contig4-2569_0008|orf6.3067|CA1524|CaO19.3794|CaO19.11274 Putative zinc-finger transcription factor involved in zinc homeostasis; involved in negative regulation of biofilm matrix; similar to S. cerevisiae Zap1p; mutation affects filamentous growth; suppresses S. cerevisiae rok1 mutant inviability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1048066 1049692 + orf19.3793 1048066 1049692 1 1048066 1049692 1048357 1049574 orf19.11273|IPF6913.2|IPF28637.1|Contig4-2349_0003|orf6.3066|orf6.758|CA0173|CaO19.3793|IPF6913 Putative protein of unknown function; mRNA binds to She3p; regulated by Nrg1p; greater mRNA abundance observed in a cyr1 or ras1 homozygous null mutant than in wild type; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1049716 1052304 - orf19.3792 1049716 1052304 1 1052304 1049716 1052250 1049893 orf19.11272|IPF16676.3|IPF6915.2|Contig4-2349_0001|orf6.3065|orf6.757|CA1523|PAT1|CaO19.3792 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1053024 1053998 + orf19.3791 1053024 1053998 1 1053024 1053998 1053028 1053975 FGR10 orf19.11270|IPF18742.2|IPF6916.1|Contig4-2732_0021|orf6.2561|orf6.3064|CA1522|CaO19.3791|IPF6916 Putative asparaginase; lacks ortholog in S. cerevisiae; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1053235 1055066 - orf19.3789 1053235 1055066 2 1055066|1054631 1054984|1053235 1054625 1054158 RPL24A IPF18743.1|IPF6918.1|Contig4-2732_0018|Contig4-2732_0019|orf6.2560|orf6.3062|CA1189|RPL24|CaO19.3789 Predicted ribosomal protein; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage; intron in 5'-UTR [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1055368 1056072 + orf19.3788.1 1055368 1056072 2 1055368|1055633 1055451|1056072 1055449 1055950 RPL30 IPF6920.1|IPF19420.2|Contig4-2732_0016|CA1188|RPL30.3f|RPL30.3 Similar to S. cerevisiae L30 ribosomal subunit; pre-mRNA is alternatively spliced to productive and unproductive transcripts; splicing is temperature-regulated; colony morphology-related gene regulation by Ssn6p; regulated by Nrg1p, Tup1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1055984 1056886 - orf19.3788 1055984 1056886 1 1056886 1055984 1056829 1056086 orf19.11268|IPF23477.1|IPF6922.2|Contig4-2732_0015|orf6.152|orf6.2559|CA0023|CaO19.3788|IPF6922 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1057031 1058631 + orf19.3787 1057031 1058631 1 1057031 1058631 1057101 1058219 orf19.11267|IPF19904.1|IPF19825.2|Contig4-2732_0011|Contig4-2732_0013|orf6.153|orf6.2558|CA1187|QRI7|KAE1|CaO19.3787 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1058155 1059332 - orf19.3785 1058155 1059332 1 1059332 1058155 1059239 1058403 orf19.11265|IPF23469.1|IPF6930.1|Contig4-2732_0010|orf6.2556|CA1186|CaO19.3785|CaO19.11265|IPF6930 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1059566 1060509 + orf19.3784 1059566 1060509 1 1059566 1060509 1059628 1060509 IPF19903.1|IPF28638.1|Contig4-2732_0007|orf6.2555|CA1185|CaO19.3784|IPF19903.5f|IPF19903 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1060538 1061006 + orf19.3783 1060538 1061006 1 1060538 1061006 1060560 1061006 orf19.11264|IPF28639.1|Contig4-2732_0006|CA6282|CaO19.3783|IPF19903.3f Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1062272 1063255 - orf19.3782.2 1062272 1063255 2 1063255|1063013 1063182|1062272 1062999 1062736 IPF23425.1|IPF14802.1|Contig4-2732_0004|CA1184|IPF14802 ORF Predicted by Annotation Working Group; intron in 5'-UTR [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1063858 1065733 + orf19.3782 1063858 1065733 1 1063858 1065733 1063925 1065586 orf19.11263|IPF14805.2|IPF28636.1|Contig4-2732_0001|Contig4-2732_0003|orf6.2554|CA1183|CaO19.11263|CaO19.3782|IPF14805 Predicted membrane transporter, member of the peptide-acetyl-coA transporter (PAT) family, major facilitator superfamily (MFS); transcription is induced in response to alpha pheromone in Spider medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1065601 1067220 - orf19.3781 1065601 1067220 1 1067220 1065601 1067081 1065681 orf19.11262|IPF23459.1|IPF15222.3|orf6.1130|orf6.2553|CA0325|CaO19.3781|IPF15222|IPF15222.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1068098 1069490 + orf19.3780 1068098 1069490 1 1068098 1069490 1068165 1069463 orf19.11261|orf6.1131|IPF18745.2|IPF15220.2|Contig4-2648_0002|Contig4-2648_0003|orf6.2552|CA0326|CaO19.3780|IPF15220 Protein likely to be essential for growth, based on an insertional mutagenesis strategy [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1069603 1071270 + orf19.3778 1069603 1071270 1 1069603 1071270 1069672 1071231 orf19.11259|orf19.11260|IPF23474.1|IPF23478.1|IPF15219.2|IPF15217.2|Contig4-2648_0005|Contig4-2648_0007|orf6.2592|orf6.1133|orf6.1132|CA0328|CA0327|orf19.3779|IPF15217.3f Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU); downregulated in core stress response; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1071335 1071908 + orf19.3777 1071335 1071908 1 1071335 1071908 1071383 1071754 orf19.11258|IPF13432.2|IPF15216.2|orf6.1134|orf6.2593|CA0329|CaO19.3777|IMG2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1071751 1076908 - orf19.3775 1071751 1076908 1 1076908 1071751 1076415 1071964 SSK2 orf19.11257|IPF13431.2|IPF28626.1|IPF19716.1|Contig4-2648_0009|orf6.2292|orf6.2594|CA6281|CA1205|orf19.3776|SSK2.5f Protein described as similar to MAP kinase kinase kinases; transcription is downregulated in response to treatment with ciclopirox olamine [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1077037 1078100 + orf19.3774.1 1077037 1078100 1 1077037 1078100 1077301 1077522 IPF15404.1|IPF18792.1|Contig4-2542_0003|CA1206|HUB1 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1077583 1079314 - orf19.3774 1077583 1079314 1 1079314 1077583 1078892 1077642 PPG1 orf19.11256|IPF18739.1|IPF15402.2|Contig4-2542_0004|Contig4-2542_0005|orf6.2291|orf6.2595|CA1207|CaO19.3774 Putative protein phosphatase of the Type 2A-related family (serine/threonine-specific), similar to S. cerevisiae Ppg1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1080025 1082390 + orf19.3773 1080025 1082390 1 1080025 1082390 1080242 1082263 orf19.11255|IPF17195.2|IPF18793.1|IPF15400.2|Contig4-2542_0009|Contig4-2542_0011|Contig4-2542_0012|orf6.2289|orf6.2596|orf6.2290|CA1208|CA6280|orf19.3772|CaO19.3773|IPF17195.5f Putative RNAse III, ortholog of S. cerevisiae RNT1; predicted ORF in Assemblies 19, 20 and 21; merged with orf19.3772 in Assembly 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1082177 1083810 - orf19.3770 1082177 1083810 1 1083810 1082177 1083762 1082395 ARG8 orf19.11254|IPF13486.2|IPF18794.1|IPF17196.2|Contig4-2542_0013|orf6.2288|orf6.2597|orf6.2287|CA6279|CA1209|orf19.3771|ARG8.5f Predicted ORF in Assemblies 19, 20 and 21; Gcn2p-, Gcn4p-regulated; transcription is upregulated in both intermediate and mature biofilms [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1083954 1086209 - orf19.3769 1083954 1086209 1 1086209 1083954 1086089 1084026 orf19.11253|IPF23445.1|IPF13485.2|Contig4-2542_0016|Contig4-2542_0017|orf6.2286|orf6.2598|CA1019|ZRG17|CaO19.3769|IPF13485 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1086388 1086611 + ntar_803 1086388 1086611 1 1086388 1086611 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1086494 1091938 - orf19.736 1086494 1091938 1 1091938 1086494 1091860 1086617 orf19.11252|orf19.8355|IPF23494.1|IPF13479.2|IPF26554.1|IPF16695.2|Contig4-1880_0002|orf6.526|orf6.2285|CA1018|CA0102|orf19.3768|IPF16695.5eoc|IPF16695 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr4 1092188 1096267 - orf19.738 1092188 1096267 1 1096267 1092188 1096185 1092235 MYO5 orf19.8357|IPF14461.3|IPF29710.1|orf6.2409|orf6.528|CA1087|CaO19.738|IPF14461.2 Class I myosin; nonessential; role in cortical actin patch polarity and polar budding; required for hyphal growth; regulatory phosphorylation on S366; downregulated on adherence to polystyrene; sole class I myosin in C. albicans [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1097096 1099574 - orf19.740 1097096 1099574 2 1099574|1098459 1099275|1097096 1099281 1097336 HAP41 orf19.8359|IPF26555.1|IPF13319.2|Contig4-2600_0002|orf6.2411|CA1088|CaO19.740|CaO19.8359|IPF13319 Predicted ORF in Assemblies 19, 20 and 21; not required for response to low iron; possibly spurious ORF (Annotation Working Group prediction); transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1100824 1101332 - ntar_804 1100824 1101332 1 1101332 1100824 1101248 1101126 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1101018 1101596 + ntar_805 1101018 1101596 1 1101018 1101596 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1101663 1102134 - ntar_806 1101663 1102134 1 1102134 1101663 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1103178 1103346 + ntar_807 1103178 1103346 1 1103178 1103346 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1103363 1103793 + ntar_808 1103363 1103793 1 1103363 1103793 1103363 1103539 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1104396 1104710 - orf19.741 1104396 1104710 1 1104710 1104396 1104710 1104396 orf19.8360|IPF26562.1|IPF18494.1|orf6.4130|CaO19.8360|CaO19.741 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 1104814 1106849 - orf19.742 1104814 1106849 1 1106849 1104814 1106556 1104883 ALD6 orf19.8361|IPF26552.1|IPF16300.2|Contig4-2969_0013|orf6.4131|CA2290|CaO19.8361|CaO19.742|IPF16300 Expression is regulated upon white-opaque switching; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1107180 1107741 - ntar_809 1107180 1107741 1 1107741 1107180 1107341 1107207 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1107817 1108566 + ntar_810 1107817 1108566 1 1107817 1108566 1107817 1107948 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1108493 1113255 - orf19.744 1108493 1113255 1 1113255 1108493 1113201 1108618 GDB1 orf19.8363|IPF26560.1|IPF9743.2|IPF9740|orf6.4133|CA2291|CaO19.744|CaO19.8363 Putative glycogen debranching enzyme; expression is regulated upon white-opaque switching; regulated by Nrg1p, Tup1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr4 1114995 1117446 + orf19.745 1114995 1117446 1 1114995 1117446 1115505 1117262 VAC8 orf19.8364|IPF26550.1|IPF9747.1|Contig4-2360_0004|orf6.4134|CA2292|CaO19.8364|CaO19.745 Protein involved in vacuolar inheritance; required for hyphal growth; contains armadillo repeats [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1117391 1119141 - orf19.746 1117391 1119141 1 1119141 1117391 1119048 1117501 orf19.8365|IPF26553.1|IPF9748.2|Contig4-2360_0002|Contig4-2360_0003|orf6.4135|CA2293|CaO19.746|CaO19.8365|IPF9748 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1119314 1120639 - orf19.747 1119314 1120639 1 1120639 1119314 1120639 1119419 NBP35 orf19.8367|IPF26556.1|IPF19946.1|Contig4-2360_0001|orf6.4136|CA2294|CaO19.747|IPF19946 Similar to nucleotide-binding proteins; increased transcription is observed upon benomyl treatment; transcription is induced upon filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr4 1120789 1125132 - orf19.748 1120789 1125132 1 1125132 1120789 1125132 1120885 orf19.8368|orf19.14146|orf19.14147|IPF20259.1|IPF8467.2|IPF26549.1|IPF16922.2|Contig4-2307_0003|Contig4-2307_0004|orf6.4137|orf6.7005|orf6.7006|CA4459|CA4460|orf19.6856|orf19.6857|CaO19.748|NUP145 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1125151 1126783 - orf19.6858 1125151 1126783 1 1126783 1125151 1126754 1125216 orf19.14148|IPF8470|IPF20272.1|IPF8470.2|Contig4-2307_0005|orf6.7007|CA4461|CaO19.6858 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1127126 1127599 - orf19.6859 1127126 1127599 1 1127599 1127126 1127599 1127126 orf19.14149|IPF20287.1|IPF17251.1|Contig4-1532_0003|Contig4-2307_0006|orf6.7008|CA4462|CaO19.6859|IPF17251 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 1128599 1129763 + orf19.6860 1128599 1129763 1 1128599 1129763 1128823 1129515 orf19.14150|IPF20282.1|IPF9827.2|Contig4-2844_0001|orf6.7009|CA4463|CaO19.14150|PIS1|CaO19.6860 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1129479 1132090 - orf19.6861 1129479 1132090 1 1132090 1129479 1132050 1129654 orf19.14151|IPF20261.1|IPF9828.2|Contig4-2844_0002|orf6.7010|CA4464|APC5|CaO19.6861|CaO19.14151|IPF9828 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1132137 1134570 - orf19.6862 1132137 1134570 1 1134570 1132137 1134550 1132241 orf19.14152|IPF20266.1|IPF9829.1|Contig4-2844_0004|orf6.7011|CA4465|CaO19.6862|CaO19.14152|IPF9829 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1134842 1137513 - orf19.6863 1134842 1137513 1 1137513 1134842 1137404 1134939 VPH1 orf19.14153|IPF20260.1|IPF9830.1|Contig4-2844_0005|orf6.7012|CA4466|CaO19.14153|CaO19.6863 Predicted ORF in Assemblies 19, 20 and 21; transcription is regulated by Nrg1p, Mig1p, and Tup1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1139183 1139890 + orf19.6864 1139183 1139890 1 1139183 1139890 1139183 1139890 orf19.14154|IPF20286.1|IPF9833.1|Contig4-2844_0011|orf6.7013|CA4467|CaO19.6864|CaO19.14154|IPF9833 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 1140096 1144432 + orf19.2631 1140096 1144432 1 1140096 1144432 1140158 1144204 orf19.14155|IPF15693.2|IPF18972.1|IPF20275.1|IPF9835.1|Contig4-2844_0012|orf6.850|orf6.1436|orf6.7014|CA0204|orf19.1222|orf19.6865|CaO19.2631 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1144130 1144970 - orf19.2630 1144130 1144970 1 1144970 1144130 1144940 1144293 RAD59 IPF16191.2|orf6.1435|CA0479|CaO19.2630|IPF16191 Protein similar to S. cerevisiae Rad59p; N-terminal similarity with Rad52p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1145084 1151627 + orf19.2629 1145084 1151627 1 1145084 1151627 1145110 1151538 IPF10478.3|IPF19694.1|Contig4-2660_0013|Contig4-2660_0014|Contig4-2660_0015|orf6.1433|orf6.912|orf6.913|orf6.1434|CA6235|CA6236|orf19.1293|orf19.1294|USO1.5eoc Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr4 1151753 1154391 + orf19.1291 1151753 1154391 1 1151753 1154391 1151753 1154221 ABZ1 orf19.9352|orf19.9353|IPF10474.2|Contig4-2660_0010|Contig4-2660_0012|orf6.1155|orf6.910|orf6.1154|CA0220|orf19.1786|orf19.1787|CaO19.1291 Protein not essential for viability; similar to S. cerevisiae Abz1p, which is para-aminobenzoate (PABA) synthase; reports differ on whether a murine homolog exists [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr4 1154590 1156710 + orf19.1290 1154590 1156710 1 1154590 1156710 1154642 1156606 XKS1 orf19.9354|IPF19103.2|IPF25535.1|IPF25530.1|IPF10471.2|IPF10472.2|Contig4-2660_0006|orf6.909|orf6.1156|CA0341|orf19.1788 Predicted ORF in Assemblies 19, 20 and 21; increased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1156891 1158405 + orf19.1789 1156891 1158405 1 1156891 1158405 1156891 1158354 orf19.9355|IPF25532.1|IPF10470.2|Contig4-2660_0001|orf6.1157|CA0342|CaO19.9355|CaO19.1789|IPF10470 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1158811 1160359 + orf19.1789.1 1158811 1160359 1 1158811 1160359 1159049 1160197 LYS1 orf19.9356|IPF25528.1|IPF25539.1|IPF29306.1|IPF10469.3|Contig4-2934_0006|orf6.1158|CA0343|orf19.1790|CA2460|LYS1.3eoc|IPF18465.1|LYS1.5eoc|IPF10469.2 Saccharopine dehydrogenase (biosynthetic); enzyme of alpha-aminoadipate lysine biosynthesis pathway; functionally complements S. cerevisiae lys1 mutation; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1160168 1161894 - orf19.1791 1160168 1161894 1 1161894 1160168 1161801 1160326 orf19.9357|IPF25533.1|IPF8738.2|Contig4-1853_0004|orf6.4370|CA2461|MAK11 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1162041 1164438 + orf19.1792 1162041 1164438 1 1162041 1164438 1162041 1164398 orf19.9358|IPF25526.1|IPF8736.2|Contig4-1853_0002|orf6.4371|CA2462|CaO19.9358|CDC16|CaO19.1792 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr4 1165692 1166763 - ntar_811 1165692 1166763 1 1166763 1165692 1166409 1166251 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1165981 1166170 + ntar_812 1165981 1166170 1 1165981 1166170 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1166853 1169063 + orf19.1793 1166853 1169063 1 1166853 1169063 1167226 1169013 orf19.9359|IPF8730|IPF25531.1|IPF8730.2|Contig4-2654_0004|orf6.4372|CA2463|CaO19.1793|CaO19.9359 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1169191 1170369 - orf19.1794 1169191 1170369 1 1170369 1169191 1170295 1169213 orf19.9360|IPF25538.1|IPF8727.1|Contig4-2654_0005|orf6.4373|CA2464|CaO19.9360|CaO19.1794|IPF8727 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr4 1170885 1174081 + orf19.1795 1170885 1174081 1 1170885 1174081 1171147 1173936 PUF3 orf19.9361|IPF8726|IPF25523.1|IPF8726.2|Contig4-2654_0006|orf6.4374|CA2465|CaO19.9361|CaO19.1795 Protein not essential for viability; similar to S. cerevisiae Puf3p, which is an mRNA-binding protein involved in RNA catabolism [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1174123 1174669 - orf19.1795.1 1174123 1174669 1 1174669 1174123 1174572 1174324 CA2466|IPF8725|IPF8725.2 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1174880 1176241 + orf19.1796 1174880 1176241 1 1174880 1176241 1174948 1176042 orf19.9362|IPF25537.1|IPF8724.2|Contig4-2654_0009|orf6.4375|CA2467|CaO19.9362|CaO19.1796|IPF8724 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1176248 1178442 - orf19.1797 1176248 1178442 1 1178442 1176248 1177569 1176382 orf19.9363|IPF25536.1|IPF8723.2|orf6.4376|CA2468|CaO19.9363|CaO19.1797|IPF8723 Predicted ORF in Assemblies 19, 20 and 21; induced upon biofilm formation; has GutQ domain, which is associated with phosphosugar binding [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1178453 1178664 + ntar_813 1178453 1178664 1 1178453 1178664 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1179153 1183979 - orf19.1798 1179153 1183979 1 1183979 1179153 1183964 1179489 TSC2 orf19.9364|IPF7393|IPF7393.2|IPF29308.1|Contig4-2057_0001|Contig4-2807_0001|orf6.4377|CA2469|CaO19.1798 Putative GTPase-activating protein involved in control of filamentous growth; not essential for viability; similar to mammalian tuberin [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr4 1184139 1186164 - orf19.1799 1184139 1186164 1 1186164 1184139 1186101 1184245 orf19.9365|IPF19643.2|IPF19644.1|Contig4-3019_0033|orf6.2231|orf6.4378|GAP6|CA0981|GAP12|CaO19.1799|GAP4 Putative general amino acid permease; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1186496 1188153 - orf19.1800 1186496 1188153 1 1188153 1186496 1187977 1186649 orf19.9366|IPF25534.1|IPF7397.2|Contig4-2461_0003|orf6.2232|CA0982|VPS62|CaO19.1800|CaO19.9366|IPF7397 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1186516 1187012 + ntar_814 1186516 1187012 1 1186516 1187012 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1187156 1187435 + ntar_815 1187156 1187435 1 1187156 1187435 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1188539 1189910 - orf19.1801 1188539 1189910 1 1189910 1188539 1189820 1188936 orf19.9367|IPF25540.1|IPF7398.2|Contig4-2461_0005|orf6.2233|CA0983|CaO19.1801|CBR1|CaO19.9367 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1190511 1192557 - orf19.1802 1190511 1192557 1 1192557 1190511 1192479 1190626 orf19.9368|IPF25529.1|IPF7400.2|Contig4-2461_0007|Contig4-2461_0009|orf6.2234|CA0984|CaO19.1802|IPF7400 Predicted ORF in Assemblies 19, 20 and 21; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1192610 1193293 + ntar_816 1192610 1193293 1 1192610 1193293 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1194098 1194751 - ntar_817 1194098 1194751 1 1194751 1194098 1194751 1194554 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1204774 1206312 + orf19.1234 1204774 1206312 1 1204774 1206312 1204774 1206312 FGR6-10 orf19.8819|IPF26070.1|IPF10582.1|Contig4-1717_0002|Contig4-2111_0005|orf6.5083|CA2978|CaO19.8819|CaO19.1234|IFV2 Protein lacking an ortholog in S. cerevisiae; member of a family encoded by FGR6-related genes in the RB2 repeat sequence; transposon mutation affects filamentous growth [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 1210068 1212014 + orf19.1235 1210068 1212014 1 1210068 1212014 1210282 1211916 HOM3 orf19.8820|IPF26072.1|IPF14675.2|orf6.5082|CA2977|CaO19.8820|CaO19.1235 Putative L-aspartate 4-P-transferase; fungal-specific (no human or murine homolog); regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1211915 1213206 - orf19.1236 1211915 1213206 1 1213206 1211915 1213108 1212143 orf19.8821|IPF14676.2|IPF12543.2|Contig4-2681_0004|orf6.5081|orf6.710|CA2976|CaO19.1236|IPF14676 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1213348 1213827 + ntar_818 1213348 1213827 1 1213348 1213827 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1213456 1215132 - orf19.1237 1213456 1215132 1 1215132 1213456 1215124 1213553 ARO9 orf19.8822|IPF14677.1|IPF12542.2|Contig4-2681_0003|orf6.5080|orf6.711|CA2975|CaO19.1237 Aromatic transaminase of the Ehrlich fusel oil pathway of aromatic alcohol biosynthesis; Rim101p-dependent pH-regulation (alkaline induced) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1215383 1217139 - orf19.1238 1215383 1217139 2 1217139|1217016 1217097|1215383 1217104 1215528 TUB4 orf19.8823|IPF26076.1|IPF12541.2|Contig4-2139_0001|Contig4-2681_0002|orf6.5079|orf6.712|CA0159|TUB4.3 Putative gamma-tubulin; induced upon adherence to polystyrene; transcription is regulated by Nrg1p and Mig1p; periodic mRNA expression, peak at cell-cycle S/G2 phase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1217355 1219099 - orf19.1239 1217355 1219099 1 1219099 1217355 1219046 1218060 orf19.8824|IPF12540.1|IPF29520.1|Contig4-2139_0003|orf6.5078|CA2974|CaO19.1239|CaO19.8824|IPF12540 Predicted ORF in Assemblies 19, 20 and 21; exogenously expressed protein is a substrate for Kex2p processing in vitro; fluconazole-downregulated; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1221392 1229685 + orf19.1240 1221392 1229685 1 1221392 1229685 1221392 1229599 orf19.8825|IPF26084.1|IPF9887.3|orf6.2676|orf6.5077|CA1261|CaO19.1240|IPF9887|IPF9887.3eoc|IPF9887.2 Predicted ORF in Assemblies 19, 20 and 21; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr4 1230003 1233704 + orf19.1244 1230003 1233704 1 1230003 1233704 1230716 1233544 GYP2 orf19.8829|IPF26053.1|IPF9881.2|Contig4-2415_0004|orf6.2680|CA1262|CaO19.1244|CaO19.8829|MDR1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1233601 1237083 - orf19.1246 1233601 1237083 1 1237083 1233601 1237024 1233893 orf19.8830|IPF15574.3|IPF9880.2|Contig4-2415_0005|Contig4-2415_0007|orf6.2682|orf6.3013|CA1263|CaO19.1246|IPF9880 Predicted ORF in Assemblies 19, 20 and 21; greater mRNA abundance observed in a cyr1 homozygous null mutant than in wild type [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1237151 1238052 - orf19.1247 1237151 1238052 1 1238052 1237151 1237944 1237483 orf19.8831|IPF15575.2|IPF18723.2|Contig4-1942_0002|orf6.2683|orf6.3012|CA1482|CaO19.1247|IPF15575 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1238098 1239260 + orf19.1248 1238098 1239260 1 1238098 1239260 1238180 1239136 orf19.8832|IPF15576.2|IPF18722.2|Contig4-1942_0004|orf6.3011|CA1481|CaO19.8832|RPB3|CaO19.1248 Putative protein of unknown function; heterozygous null mutant exhibits resistance to parnafungin in the C. albicans fitness test; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1239045 1240123 - orf19.1249 1239045 1240123 1 1240123 1239045 1240045 1239206 orf19.8833|IPF26083.1|IPF15577.2|Contig4-1942_0005|orf6.3010|CA1480|CaO19.8833|HIS6|CaO19.1249 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1240109 1241365 + orf19.1250 1240109 1241365 1 1240109 1241365 1240249 1241235 orf19.8834|IPF26082.1|IPF16428.2|orf6.3009|CA1479|CaO19.1250|CaO19.8834|IPF16428 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1241159 1243646 - orf19.1251 1241159 1243646 1 1243646 1241159 1243508 1241271 BRN1 orf19.8835|IPF26062.1|IPF16426.2|Contig4-2236_0005|orf6.3008|CA1478|CaO19.8835|CaO19.1251|IPF16426 Predicted ORF in Assemblies 19, 20 and 21; cell-cycle regulated periodic mRNA expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1245652 1248071 + orf19.1252 1245652 1248071 1 1245652 1248071 1245692 1247755 YME1 orf19.8836|IPF26065.1|IPF14644.2|Contig4-2236_0003|orf6.3007|CA1477|CaO19.1252|CaO19.8836 Protein not essential for viability; similar to S. cerevisiae Yme1p, which is a mitochondrial inner membrane protease of the AAA family [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1249281 1251853 + orf19.1253 1249281 1251853 1 1249281 1251853 1249554 1251533 orf19.8838|IPF14649.2|IPF10541.2|Contig4-2799_0001|orf6.3005|orf6.5720|CA3452|CaO19.1253|IPF10541 Predicted ORF in Assemblies 19, 20 and 21; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1251966 1254466 + orf19.1254 1251966 1254466 1 1251966 1254466 1252053 1254341 SEC23 orf19.8839|IPF26061.1|IPF10536.2|Contig4-2799_0002|orf6.5721|CA3453|CaO19.8839|sec231|CaO19.1254 Transcription is regulated upon yeast-hyphal switch [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1256231 1259235 + orf19.1255 1256231 1259235 1 1256231 1259235 1256317 1259235 ZCF5|orf19.8841|orf19.8842|IPF26057.1|IPF26091.1|IPF10533.2|IPF19641.1|Contig4-2799_0004|orf6.2897|orf6.5722|orf6.5723|CA3454|CA3455|orf19.1256|IPF10533.5f|IPF10533.exon1 [NOT TRANSCRIBED?] Putative transcription factor with zinc cluster DNA-binding motif; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chr4 1260882 1261499 - ntar_819 1260882 1261499 1 1261499 1260882 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1262779 1263111 + orf19.1257 1262779 1263111 1 1262779 1263111 1262779 1263111 IPF29533.1|orf6.5724|CaO19.1257 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 1263855 1264824 + orf19.1258 1263855 1264824 1 1263855 1264824 1263995 1264708 orf19.8843|IPF15051.2|IPF29522.1|Contig4-2968_0001|orf6.402|orf6.5725|CA0066|CaO19.1258|IPF15051 Predicted ORF in Assemblies 19, 20 and 21; regulated by Tsa1p, Tsa1Bp in minimal media at 37 deg; transcription is induced in response to alpha pheromone in SpiderM medium; clade-associated gene expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1264805 1269414 - orf19.1259 1264805 1269414 1 1269414 1264805 1269219 1264888 orf19.8844|IPF26095.1|IPF19986.1|Contig4-2968_0002|orf6.5726|CA3456|CaO19.1259|SNT2|CaO19.8844|IPF19986 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1269588 1270598 - orf19.1260 1269588 1270598 1 1270598 1269588 1270531 1269830 LEA1 orf19.8845|IPF26087.1|IPF8521.1|Contig4-2968_0003|orf6.5727|CA3457|CaO19.8845|CaO19.1260|IPF8521 Protein similar to S. cerevisiae Lea1p; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1270687 1272275 + orf19.1261 1270687 1272275 1 1270687 1272275 1270777 1272126 CGT1 orf19.8846|IPF26081.1|IPF18334.2|IPF8518.2|IPF8519.1|Contig4-2968_0008|orf6.5728|CA3459|CGT1.3f mRNA 5' guanylyltransferase; small subunit of mRNA capping enzyme; binds an RNA Pol II C-terminal domain peptide; Cet1p and Cgt1p form a 2:1 complex; functional homolog of S. cerevisiae Ceg1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1272228 1274731 - orf19.1263 1272228 1274731 1 1274731 1272228 1274639 1272357 CFL1 orf19.8848|orf6.5730|FRE1|IPF26060.1|IPF8516.2|Contig4-2968_0009|CA3460|CaO19.8848|CaO19.1263 Protein similar to ferric reductase Fre10p; possible functional homolog of S. cerevisiae Fre1p (reports differ); transcription is negatively regulated by Sfu1p, copper, amphotericin B, caspofungin; induced by ciclopirox olamine [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1274943 1275641 - ntar_820 1274943 1275641 1 1275641 1274943 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1276847 1279353 - orf19.1264 1276847 1279353 1 1279353 1276847 1279299 1277083 CFL2 orf19.8849|orf6.5731|FRE2|IPF26059.1|IPF8512.2|CFL97|Contig4-2968_0010|Contig4-2968_0011|CA3461|CaO19.8849|CaO19.1264 Iron utilization protein; similar to an S. cerevisiae oxidoreductase, Ynr060Wp; regulated by Sfu1p, Nrg1p, Tup1p, Rim101p; alkaline, low iron, fluphenazine, ciclopirox olamine, flucytosine, induced; caspofungin, amphotericin B repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr4 1282652 1286506 + orf19.1265 1282652 1286506 1 1282652 1286506 1282684 1286478 orf19.8850|IPF26103.1|IPF14959.2|Contig4-2968_0013|orf6.5732|CA3462|TRS130|CaO19.1265|IPF14959 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1286656 1287788 + ntar_821 1286656 1287788 1 1286656 1287788 1287277 1287507 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1286907 1288182 - orf19.1266 1286907 1288182 1 1288182 1286907 1287813 1287448 orf19.8852|IPF10280.1|IPF14956.3|Contig4-1503_0003|orf6.5733|CA0944|CaO19.1266|IPF10280|orf6.2158 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1288367 1290009 + orf19.1267 1288367 1290009 1 1288367 1290009 1288486 1289871 orf19.8853|IPF10278.2|IPF29519.1|Contig4-2192_0011|orf6.2159|CA0945|CaO19.1267|DJP2|CaO19.8853|IPF10278 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1290223 1290489 + orf19.1267.1 1290223 1290489 1 1290223 1290489 1290223 1290489 IPF26052.1|IPF10277.2|Contig4-2192_0002|CA0946|IPF10277 ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1290702 1291043 + orf19.1268 1290702 1291043 1 1290702 1291043 1290702 1291043 orf19.8854|IPF26094.1|IPF29526.1|Contig4-2192_0003|Contig4-2192_0004|orf6.2160|CaO19.1268|CaO19.8854 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1291382 1293565 + orf19.1270 1291382 1293565 1 1291382 1293565 1291382 1293565 orf19.8856|IPF26063.1|IPF10273.2|FRE3|CFL99|CFL3|Contig4-2192_0007|orf6.2162|CA0947|CaO19.8856|CaO19.1270 Predicted ORF in Assemblies 19, 20 and 21; similar to ferric reductase Fre10p [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr4 1293601 1295117 - orf19.1272 1293601 1295117 1 1295117 1293601 1295087 1293849 orf19.8858|IPF26080.1|IPF10270.2|Contig4-2192_0009|orf6.2164|CA0948|CaO19.8858|CaO19.1272|IPF10270 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1295782 1296305 + orf19.1273 1295782 1296305 1 1295782 1296305 1295913 1296305 orf19.8859|IPF10269.1|IPF29523.1|Contig4-2799_0007|orf6.2165|CA0949|CaO19.1273|GIM3|CaO19.8859|IPF10269 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr4 1296853 1298544 - orf19.1274 1296853 1298544 1 1298544 1296853 1298544 1296853 orf19.8861|IPF10266.2|Contig4-1689_0001|Contig4-2799_0004|orf6.2166|CaO19.1274 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 1301408 1304142 + orf19.1275 1301408 1304142 1 1301408 1304142 1302003 1304069 GAT1 orf19.8862|orf6.2898|GAT99|IPF26064.1|IPF12290.2|Contig4-2741_0008|CA1410|CaO19.8862|CaO19.1275 Zinc finger transcriptional regulator of nitrogen utilization; required for nitrogen catabolite repression and utilization of isoleucine, tyrosine and tryptophan N sources; required for virulence in a mouse systemic infection model [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1304376 1305227 + orf19.1276 1304376 1305227 1 1304376 1305227 1304540 1305046 orf19.8863|IPF26090.1|IPF12292.2|orf6.2899|YOR054|CA6187|CaO19.1276|CaO19.8863|IPF12292 Predicted ORF in Assemblies 19, 20 and 21; not essential for viability; similar to S. cerevisiae Vhs3p, which is a putative phosphopantothenoylcysteine decarboxylase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1305099 1306752 - orf19.1277 1305099 1306752 1 1306752 1305099 1306454 1305276 orf19.8864|IPF19348.2|IPF11858.2|Contig4-2741_0002|orf6.2900|orf6.303|CA1411|CaO19.1277|IPF11858 Predicted ORF in Assemblies 19, 20 and 21; repressed by Rgt1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1309148 1312806 - orf19.4403 1309148 1312806 1 1312806 1309148 1312615 1309313 VPS11 orf19.11881|orf19.8865|IPF26100.1|IPF11854.3|IPF19197.2|IPF11853.2|Contig4-2866_0002|orf6.2901|orf6.2825|orf6.656|CA1412|CA1361|orf19.1278|CaO19.4403|PEP5 Protein involved in protein trafficking; putative role in vesicle-target membrane fusion; mutant lacks vacuole; role in hyphal growth, possibly via vacuole expansion into hypha; role in killing of and survival within macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1312798 1315316 + ntar_822 1312798 1315316 1 1312798 1315316 1312798 1313097 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1312956 1315160 - orf19.4404 1312956 1315160 1 1315160 1312956 1315160 1312956 PGA49 orf19.11882|IPF11851.3|IPF14598.2|Contig4-2866_0003|orf6.2824|orf6.657|CA1360|CaO19.4404|IPF14598 [NOT TRANSCRIBED?] Putative GPI-anchored protein of unknown function [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 1320983 1322253 - ntar_823 1320983 1322253 1 1322253 1320983 1321458 1321219 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1320997 1324241 + orf19.4405 1320997 1324241 1 1320997 1324241 1321074 1324130 PPS1 orf19.11883|IPF22864.1|IPF11842.2|Contig4-2866_0017|orf6.2823|CA1359|CaO19.11883|CaO19.4405|IPF11842 Putative dual specificity protein phosphatase, similar to S. cerevisiae Pps1p; mutant shows virulence defect [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr4 1324892 1325096 - ntar_824 1324892 1325096 1 1325096 1324892 1325096 1324965 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1325061 1325132 - tt(ugu)2 1325061 1325132 1 1325132 1325061 tT(UGU)2.2 tRNA-Thr predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 1325600 1326705 + orf19.4406 1325600 1326705 2 1325600|1325756 1325683|1326705 1325647 1326561 orf19.11884|IPF11838.3|IPF11837.2|Contig4-2866_0019|orf6.2822|orf6.400|CA1358|NIF3|CaO19.4406 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1326846 1329216 + orf19.4407 1326846 1329216 1 1326846 1329216 1327013 1329091 orf19.11885|IPF11835.3|IPF28414.1|orf6.2975|orf6.401|CA0065|CaO19.4407|IPF11835|CA1456|IPF11835.3eoc|IPF15083.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1329186 1331379 - orf19.4409 1329186 1331379 1 1331379 1329186 1331300 1329225 orf19.11887|IPF15081|IPF22844.1|IPF15081.2|orf6.2973|CA1455|CaO19.11887|CaO19.4409 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1331637 1331718 + ts(uga)2 1331637 1331718 1 1331637 1331718 tS(UGA)2.2 tRNA-Ser predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 1331810 1333311 + orf19.4410 1331810 1333311 1 1331810 1333311 1331871 1333241 ALG1 orf19.11888|IPF22854.1|IPF19918.1|Contig4-1803_0004|orf6.2972|CA1454|CaO19.4410|CaO19.11888 Protein likely to be essential for growth, based on an insertional mutagenesis strategy; similar to S. cerevisiae Alg1p, which is a mannosyltransferase involved in N-linked protein glycosylation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1333125 1334577 - orf19.4411 1333125 1334577 1 1334577 1333125 1334577 1333267 HOS1 orf19.11889|IPF22853.1|IPF6469.2|Contig4-1803_0002|orf6.2971|CA1453|CaO19.11889|CaO19.4411 Histone deacetylase; similar to S. cerevisiae Hos1p; has conserved deacetylation motif; slightly greater expression in white cells than in opaque cells [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1334619 1337981 - orf19.4412 1334619 1337981 1 1337981 1334619 1337960 1334619 orf19.11890|IPF22862.1|IPF6472.2|orf6.2970|orf6.4227|CA1452|REV1|CaO19.4412 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1338154 1339089 + orf19.4413 1338154 1339089 2 1338154|1338426 1338203|1339089 1338201 1338872 CMD1 orf19.11891|IPF16778.1|IPF6473.1|Contig4-2875_0013|orf6.2969|orf6.4226|CA1451|CaO19.4413|CMD1.3f Calmodulin; calmodulin inhibitors cause a defect in hyphal growth; not transcriptionally regulated by yeast-hyphal transition; mutation confers hypersensitivity to cytochalasin D and high concentrations of tunicamycin; gene has intron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1339152 1340446 + orf19.4414 1339152 1340446 1 1339152 1340446 1339277 1340446 orf19.11892|IPF16776.2|IPF6474.1|Contig4-2875_0012|orf6.2968|orf6.4225|CA1450|CaO19.4414|IPF6474 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1340611 1341549 + orf19.4415 1340611 1341549 1 1340611 1341549 1340790 1341398 orf19.11893|IPF18480.1|IPF6475.2|Contig4-2875_0010|orf6.2967|orf6.4224|CA2354|CaO19.4415|IPF18480 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1341961 1351271 + orf19.4416 1341961 1351271 1 1341961 1351271 1341961 1351212 VPS13 orf19.11894|IPF22856.1|IPF19756.1|Contig4-2875_0007|Contig4-2875_0009|orf6.4223|CA2353|CaO19.11894|CaO19.4416 Predicted ORF in Assemblies 19, 20 and 21; gene used for multilocus sequence typing [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr4 1351158 1352460 - orf19.4418 1351158 1352460 1 1352460 1351158 1352431 1351352 FMT1 orf19.11896|IPF22855.1|IPF6482.2|Contig4-2875_0006|orf6.4221|CA2352|CaO19.4418|CaO19.11896 Protein described as a methionyl-tRNA transformylase; induced upon adherence to polystyrene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1352454 1353448 + orf19.4418.1 1352454 1353448 1 1352454 1353448 1352612 1352788 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1352777 1355224 - orf19.4420 1352777 1355224 1 1355224 1352777 1355224 1352822 orf19.11898|IPF22843.1|IPF19947.1|Contig4-2875_0014|orf6.4219|CA2351|CaO19.4420|RRN6|CaO19.11898|IPF19947 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1355400 1358107 + orf19.4719 1355400 1358107 1 1355400 1358107 1355471 1357963 CWH41 orf19.11899|GLS1|PRB1|IPF22852.1|IPF15907.2|IPF8229.2|Contig4-2812_0012|orf6.4218|orf6.3155|CA2350|CA1581|orf19.4421|CaO19.4719|CWH41.3eoc Processing alpha glucosidase I, involved in N-linked protein glycosylation and assembly of cell wall beta 1,6 glucan [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1357996 1360304 - orf19.4718 1357996 1360304 1 1360304 1357996 1360213 1358105 TRP5 IPF8232.2|Contig4-2812_0008|Contig4-2812_0010|orf6.3154|CA1580|CaO19.4718 Predicted tryptophan synthase; Gcn4p-regulated; upregulated in biofilm; identified in detergent-resistant membrane fraction (possible lipid raft component); predicted N-terminal acetylation; S. cerevisiae ortholog is Gcn4p regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1362478 1364188 + orf19.4716 1362478 1364188 1 1362478 1364188 1362564 1363934 GDH3 IPF8236.1|Contig4-2812_0004|orf6.3152|CA1579|CaO19.4716|GDH1 Protein described as similar to NADP-glutamate dehydrogenase; hyphal downregulated expression; transcription is regulated by Nrg1p, Plc1p; downregulated by Efg1p; upregulated by Rim101p at pH 8; ciclopirox olamine induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1364687 1376291 + orf19.4715 1364687 1376291 1 1364687 1376291 1364687 1376167 orf19.10441|IPF24455.1|IPF15988.2|IPF8243.2|Contig4-2802_0015|orf6.3454|orf6.3151|CA1797|CA1578|orf19.2924|NUM11.5eoc|NUM11 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr4 1376201 1377878 - orf19.2923 1376201 1377878 1 1377878 1376201 1377736 1376309 orf19.10440|IPF24433.1|IPF11448.2|Contig4-2802_0001|orf6.3455|CA1798|CaO19.10440|CaO19.2923|IPF11448 Predicted membrane transporter, member of the drug:proton antiporter (14 spanner) (DHA2) family, major facilitator superfamily (MFS); transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1378274 1379094 - orf19.2922 1378274 1379094 4 1379094|1378718|1378437|1378318 1378770|1378525|1378384|1378274 1379094 1378274 orf19.10439|IPF24465.1|IPF11446.1|Contig4-2802_0002|orf6.3456|CA1799|IPF11446 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 1379411 1381024 + orf19.2921 1379411 1381024 1 1379411 1381024 1379468 1380976 orf19.10438|IPF17316.2|IPF11445.2|Contig4-2802_0004|orf6.168|orf6.3457|CA1800|PAC2|CaO19.2921|IPF11445 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1380752 1381590 - orf19.2920 1380752 1381590 1 1381590 1380752 1381535 1380981 orf19.10437|IPF17317.1|IPF11444.1|Contig4-2802_0005|orf6.167|orf6.3458|CA1801|CaO19.2920|IPF11444 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1382230 1382369 - snrnau4 1382230 1382369 1 1382369 1382230 Highly conserved U4 small nuclear RNA involved in splicing; ortholog of S. cerevisiae SNR14 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1382494 1386118 - orf19.2919 1382494 1386118 1 1386118 1382494 1386118 1382555 MPH1 orf19.10436|IPF24463.1|IPF11443.2|Contig4-2802_0009|orf6.3459|orf6.166|CA1802|CaO19.2919|IPF11443 Protein similar to S. cerevisiae Mph1p, which is a DNA helicase involved in DNA repair; induced under hydroxyurea treatment [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr4 1386162 1386535 + orf19.2917.1 1386162 1386535 1 1386162 1386535 1386209 1386418 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1386448 1388147 - orf19.2917 1386448 1388147 1 1388147 1386448 1388086 1386506 orf19.10434|IPF24432.1|IPF16748.2|Contig4-2802_0011|orf6.3461|CA1803|CaO19.10434|CaO19.2917|IPF16748 Putative protein of unknown function; heterozygous null mutant exhibits resistance to parnafungin in the C. albicans fitness test; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1388545 1389225 - orf19.2916 1388545 1389225 1 1389225 1388545 1389225 1388545 orf19.10433|IPF11804.2|IPF28950.1|Contig4-2490_0004|Contig4-2802_0013|orf6.1792|orf6.3462|CA0705|CaO19.2916|IPF11804 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 1389326 1391712 - orf19.2915 1389326 1391712 1 1391712 1389326 1391624 1389537 orf19.10432|IPF24419.1|IPF11806.1|Contig4-2490_0003|orf6.1791|CA0704|CaO19.10432|YND1|CaO19.2915|IPF11806 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1391767 1393280 + orf19.2914 1391767 1393280 1 1391767 1393280 1391861 1393177 orf19.10431|IPF18894.2|IPF11807.1|Contig4-2490_0001|orf6.1790|CA0703|CaO19.2914|CaO19.10431|IPF11807 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1393195 1395819 - orf19.2911 1393195 1395819 1 1395819 1393195 1395682 1393310 SEC3 orf19.10430|IPF28948.1|Contig4-2490_0006|orf6.1789|orf6.6111|CA6271|CA0702|orf19.2913|IPF11812.5f Predicted subunit of the exocyst complex, involved in exocytosis; required for hyphal growth after the first septin ring formation; interacts with septins Cdc3p, Cdc10p, and Cdc11p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1395960 1397222 + orf19.2910 1395960 1397222 1 1395960 1397222 1396431 1397141 PGA43 orf19.10428|IPF24446.1|IPF13139.2|Contig4-2946_0022|orf6.6112|CA3759|CaO19.2910|CaO19.10428|IPF13139 Putative GPI-anchored protein of unknown function [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1397014 1398339 - orf19.2909 1397014 1398339 1 1398339 1397014 1398286 1397234 ERG26 orf19.10427|IPF24436.1|IPF13138.2|Contig4-2946_0020|orf6.6113|CA3760|CaO19.10427|CaO19.2909 C-3 sterol dehydrogenase, catalyzes the second of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; amphotericin B, caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1398670 1400002 - orf19.2908 1398670 1400002 1 1400002 1398670 1399778 1398702 orf19.10426|IPF24435.1|IPF13137.1|Contig4-2946_0019|orf6.6114|CA3761|CaO19.2908|FZD4|CaO19.10426|IFR3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1400083 1401354 + orf19.2907.1 1400083 1401354 1 1400083 1401354 1400113 1400409 IPF24466.1|IPF13136.1|Contig4-2946_0018 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1400855 1401538 - orf19.2907 1400855 1401538 1 1401538 1400855 1401538 1400855 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 1401969 1402335 + ntar_825 1401969 1402335 1 1401969 1402335 1401969 1402175 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1402455 1403760 - orf19.2906 1402455 1403760 1 1403760 1402455 1403382 1402492 PGA41 orf19.10424|IPF19507.2|IPF13070.2|Contig4-2946_0014|orf6.6116|orf6.259|CA3763|CaO19.2906|IPF13070 Putative GPI-anchored protein of unknown function [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1403924 1404817 - orf19.2905 1403924 1404817 1 1404817 1403924 1404817 1404149 orf19.10423|IPF24447.1|IPF13072.2|Contig4-2946_0011|orf6.6117|CA3764|CaO19.10423|CaO19.2905|IPF13072 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr4 1404244 1404457 + ntar_826 1404244 1404457 1 1404244 1404457 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1406343 1406727 - ntar_827 1406343 1406727 1 1406727 1406343 1406537 1406343 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1407026 1410111 + orf19.2903 1407026 1410111 1 1407026 1410111 1407229 1409982 orf19.10421|orf19.10422|IPF24422.1|IPF16014.2|IPF18298.3|Contig4-2946_0009|orf6.6119|orf6.6118|CA3766|CA3765|orf19.2904|IPF18298.3f Putative Argonaute protein involved in RNA silencing, member of the Argonaute family; predicted ORF in Assemblies 19, 20 and 21; hyphal-induced expression, regulated by Cyr1p, Ras1p, Efg1p, Nrg1p, Tup1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1410017 1412256 - orf19.2901 1410017 1412256 1 1412256 1410017 1412144 1410309 NUP60 orf19.10419|IPF24425.1|IPF13471.2|Contig4-2946_0006|Contig4-2946_0007|orf6.6121|CA3767|CaO19.2901|CaO19.10419 Protein not essential for viability; similar to S. cerevisiae Nup60p, which is a subunit of the nuclear pore complex [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1412506 1413294 - orf19.2899 1412506 1413294 1 1413294 1412506 1413294 1412506 orf19.10417|IPF24439.1|IPF13467.1|Contig4-2946_0003|orf6.6123|CA3768|OAR2|CaO19.2899|CaO19.10417|IPF13467 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 1413425 1415251 - orf19.2898 1413425 1415251 1 1415251 1413425 1415251 1413566 orf19.10416|IPF24429.1|IPF13465.2|Contig4-2946_0001|orf6.6124|CA3769|CaO19.2898|CaO19.10416|IPF13465 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr4 1417178 1418020 + orf19.2897 1417178 1418020 1 1417178 1418020 1417178 1418020 SOU2 orf19.10415|IPF24440.1|IPF13462.2|Contig4-2677_0002|Contig4-2677_0004|orf6.6125|CA3770|CaO19.2897|CaO19.10415 Protein similar to Sou1p; not required for utilization of L-sorbose [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 1418783 1419850 + orf19.2896 1418783 1419850 1 1418783 1419850 1418888 1419733 SOU1 orf19.10414|IPF24438.1|IPF11150.2|Contig4-2677_0008|orf6.6126|CA3771|CaO19.2896|CaO19.10414 Enzyme involved in utilization of L-sorbose; has sorbitol dehydrogenase, fructose reductase, and sorbose reductase activities; has NAD-binding site motif; transcriptional regulation affected by chromosome 5 copy number [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1419782 1420854 - orf19.2895 1419782 1420854 1 1420854 1419782 1420702 1419899 VMA8 orf19.10413|Contig4-2677_0009|IPF24442.1|IPF11151.1|orf6.6127|CA3772|CaO19.2895|CaO19.10413 Protein similar to the S. cerevisiae Vma8p subunit of vacuolar H+-ATPase; transcription is regulated by Nrg1p and Mig1p; transcription is increased in populations of cells exposed to fluconazole over multiple generations [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1421029 1423569 + orf19.2893 1421029 1423569 1 1421029 1423569 1421029 1423566 orf19.10411|IPF11153|IPF24416.1|IPF11153.1|Contig4-2677_0010|orf6.6129|CA3773|SYF1|CaO19.10411|CaO19.2893 Putative protein of unknown function, regulation correlates with clinical development of fluconazole resistance; transcription is upregulated in an RHE model of oral candidiasis; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr4 1425944 1429456 + orf19.2892 1425944 1429456 1 1425944 1429456 1426618 1429254 orf19.10410|IPF24414.1|IPF10437.2|Contig4-2827_0022|orf6.6130|CA3774|CaO19.2892|CaO19.10410|IPF10437 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr4 1429678 1431879 - orf19.2891 1429678 1431879 1 1431879 1429678 1431586 1429955 orf19.10409|IPF24431.1|IPF10436.2|Contig4-2827_0002|orf6.6131|CA3775|AFG11|CaO19.2891|CaO19.10409|AFG1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1432073 1433527 - orf19.2890 1432073 1433527 1 1433527 1432073 1433389 1432160 orf19.10408|IPF24434.1|IPF10435.2|Contig4-2827_0007|orf6.6132|CA3776|CaO19.2890|CaO19.10408|IPF10435 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1433593 1434197 + orf19.2889 1433593 1434197 1 1433593 1434197 1433682 1434119 orf19.10407|IPF24456.1|IPF10432.2|Contig4-2827_0009|orf6.6133|CA3777|CaO19.2889|CaO19.10407|IPF10432 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1433812 1434991 - orf19.2888 1433812 1434991 1 1434991 1433812 1434862 1434188 orf19.10406|IPF24448.1|IPF10431.2|Contig4-2827_0010|orf6.6134|CA3778|CaO19.2888|CaO19.10406|IPF10431 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1435736 1435981 + ntar_828 1435736 1435981 1 1435736 1435981 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1436123 1437284 + orf19.2887 1436123 1437284 1 1436123 1437284 1436372 1436986 MET13 orf19.10405|IPF10429.2|IPF28949.1|Contig4-2827_0012|orf6.1818|orf6.6135|CA0721|CaO19.2887|IPF10429 Predicted ORF in Assemblies 19, 20 and 21; ketoconazole-induced; amphotericin B repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1437014 1439432 - orf19.2886 1437014 1439432 1 1439432 1437014 1439059 1437788 CEK1 orf19.10404|ERK1|IPF14791.2|IPF28947.1|Contig4-2827_0013|orf6.1819|CA0722|CaO19.2886 ERK-family protein kinase, required for wild-type yeast-hyphal switching, mating efficiency, and virulence in a mouse model; Cst20p-Hst7p-Cek1p-Cph1p MAPK pathway regulates mating, and invasive hyphal growth under some conditions [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1442132 1443897 - orf19.2885 1442132 1443897 1 1443897 1442132 1443855 1442224 PRI2 orf19.10403|IPF24426.1|IPF14788.3|Contig4-2827_0021|orf6.1820|CA0723|CaO19.10403|CaO19.2885|IPF14788.2 Gene adjacent to CDC68; divergently transcribed with CDC68 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1444222 1447680 + orf19.2884 1444222 1447680 1 1444222 1447680 1444317 1447499 CDC68 orf19.10402|IPF24469.1|IPF10512.3|Contig4-2689_0011|orf6.2896|CA1409|CaO19.2884|SPT16|CaO19.10402|IPF10512.2 Functional homolog of S. cerevisiae Cdc68p, which is a transcription elongation factor; essential; possible drug target [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1447511 1449050 - orf19.2883 1447511 1449050 1 1449050 1447511 1448707 1447715 CSO99 orf19.10401|IPF24437.1|IPF10513.2|Contig4-2689_0010|orf6.2895|CA1408|CaO19.10401|CSO1|CaO19.2883|IPF10513 Protein of unknown function, not conserved in S. cerevisiae [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1449510 1449969 + ntar_829 1449510 1449969 1 1449510 1449969 1449648 1449851 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1450055 1451933 - orf19.2882 1450055 1451933 1 1451933 1450055 1451933 1450158 XUT1 orf19.10400|IPF24424.1|IPF10516.2|Contig4-2689_0006|orf6.2894|CA1407|CaO19.10400|UAP2|CaO19.2882|UAPC Putative high-affinity, high-capacity xanthine-uric acid/H+ symporter; similar to A. nidulans UapA; member of the Nucleobase-Ascorbate Transporter/Nucleobase-Cation Symporter (NAT/NCS2) family [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr4 1453643 1454011 + ntar_830 1453643 1454011 1 1453643 1454011 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1453882 1454204 - ntar_831 1453882 1454204 1 1454204 1453882 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1454351 1454501 - ntar_832 1454351 1454501 1 1454501 1454351 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1456665 1457007 - ntar_833 1456665 1457007 1 1457007 1456665 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1456758 1460598 + orf19.2881 1456758 1460598 1 1456758 1460598 1457501 1460491 MNN4 orf19.10399|orf6.4390|IPF16016.2|IPF28958.1|Contig4-2084_0003|orf6.296|CA2477|CaO19.2881|IPF16016 Protein required for normal mannosylphosphorylation of oligosaccharides linked to cell wall proteins, not required for virulence or kidney colonization in mouse systemic infection or for normal interaction with macrophages [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr4 1461278 1465204 - orf19.2879 1461278 1465204 1 1465204 1461278 1465204 1461278 IFF5 orf19.10397|IPF15521.2|IPF16017.3|Contig4-2765_0012|orf6.297|orf6.4388|CA2476|CaO19.2879 [NOT TRANSCRIBED?] Putative GPI-anchored protein of unknown function [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 1461581 1465379 + ntar_834 1461581 1465379 1 1461581 1465379 1463382 1463723 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1466747 1467244 + orf19.2878 1466747 1467244 1 1466747 1467244 1466747 1467244 PGA15 orf19.10396|IPF24451.1|IPF3233.1|Contig4-2826_0011|orf6.4387|CA2475|CaO19.2878|CaO19.10396|IPF3233 Putative GPI-anchored protein of unknown function [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 1466750 1470339 - orf19.2877 1466750 1470339 1 1470339 1466750 1469944 1468241 PDC11 orf19.10395|orf6.4386|IPF24428.1|IPF3234.1|Contig4-2826_0006|Contig4-2826_0007|CA2474|PDC1|CaO19.10395|CaO19.2877 Protein similar to pyruvate decarboxylase; antigenic; at hyphal cell surface, not yeast-form cells; soluble in hyphae; regulated by Gcn4p, Efg1p, Efh1p; fluconazole-, farnesol-, biofilm-induced; repressed upon amino acid starvation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1471048 1472374 + orf19.2876 1471048 1472374 2 1471048|1471491 1471211|1472374 1471203 1472237 CBF1 orf19.10394|IPF24445.1|IPF3238.1|Contig4-2826_0005|orf6.4385|CA2473|CaO19.10394|CaO19.2876 Transcription factor that binds to a conserved sequence at ribosomal protein genes and the rDNA locus, with Tbf1p; also regulates sulfur starvation-response and other genes; binds centromeres and has a role in centromere maintenance [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1472549 1473534 + orf19.2875 1472549 1473534 1 1472549 1473534 1472576 1473400 orf19.10393|IPF24441.1|IPF3239.1|Contig4-2826_0004|orf6.4384|CA2472|CaO19.2875|CaO19.10393|IPF3239 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1473644 1478291 + orf19.2873 1473644 1478291 1 1473644 1478291 1473748 1478133 TOP2 orf19.10391|IPF24459.1|IPF3245.2|Contig4-2826_0003|Contig4-3009_0024|Contig4-3009_0025|orf6.4382|CA2471|CaO19.2873|CaO19.10391 DNA topoisomerase II; catalyzes ATP-dependent DNA relaxation and decatenation in vitro; Y842 predicted to be catalytic; functional homolog of S. cerevisiae Top2p; sensitive to amsacrine or doxorubicin; farnesol-upregulated in biofilm [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1478173 1480514 - orf19.2871 1478173 1480514 1 1480514 1478173 1480285 1478360 SDH12 orf19.10389|IPF3247.1|IPF28944.1|Contig4-3009_0023|orf6.4380|CA2470|SDHA|SDH3|SDH1|CaO19.2871|CaO19.10389 Protein with similarity to S. cerevisiae SDH1, which is a flavoprotein subunit of succinate dehydrogenase; soluble protein in hyphae; macrophage-downregulated protein level; downregulated by Efg1p; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1481449 1481901 - orf19.2870 1481449 1481901 1 1481901 1481449 1481880 1481449 orf19.10388|IPF24461.1|IPF3250.2|Contig4-3009_0020|orf6.1538|orf6.4379|CA0546|LDG11|CaO19.2870|IPF3250 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr4 1482174 1482683 - orf19.2869 1482174 1482683 1 1482683 1482174 1482683 1482174 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 1483021 1483503 - orf19.2868 1483021 1483503 1 1483503 1483021 1483503 1483021 orf19.10386|IPF24452.1|IPF3252.2|Contig4-3009_0017|orf6.1536|CA0544|CaO19.2868|LDG9|CaO19.10386|IPF3252 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 1484375 1486646 + orf19.2867 1484375 1486646 1 1484375 1486646 1484418 1486436 orf19.10385|IPF24421.1|IPF3255.2|Contig4-3009_0013|Contig4-3009_0014|orf6.1535|CA0543|CaO19.2867|VPS5|CaO19.10385|IPF3255 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1486533 1486778 - ntar_835 1486533 1486778 1 1486778 1486533 1486735 1486589 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1487112 1488662 + orf19.2866 1487112 1488662 1 1487112 1488662 1487112 1488662 orf19.10655|orf19.10384|IPF24444.1|IPF18945.2|IPF24207.1|IPF5810.3|CA6318|CA6311|orf19.3143|Cirt21.5eoc Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 1488741 1489519 - ntar_836 1488741 1489519 1 1489519 1488741 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1488795 1489286 + ntar_837 1488795 1489286 1 1488795 1489286 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1489615 1491010 + orf19.3142 1489615 1491010 1 1489615 1491010 1489718 1490917 orf19.10654|IPF24177.1|IPF3259.2|Contig4-3009_0008|orf6.1853|CA0742|CaO19.10654|CaO19.3142|IPF3259 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1490969 1493862 - orf19.3141 1490969 1493862 1 1493862 1490969 1493787 1491067 orf19.10653|IPF18322.2|IPF3261.2|Contig4-3009_0007|orf6.1852|orf6.5878|CA0741|SMY2|CaO19.3141|IPF3261 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1493995 1494419 + ntar_838 1493995 1494419 1 1493995 1494419 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1494344 1495052 - orf19.3140.1 1494344 1495052 2 1495052|1494841 1494910|1494344 1494912 1494395 IPF24216.1|IPF3262.2|Contig4-1623_0002|Contig4-3009_0006|orf6.1569|CA0740|UMP1|IPF3262.3 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1495160 1495489 + orf19.3140 1495160 1495489 1 1495160 1495489 1495160 1495489 IPF28894.1|Contig4-1623_0001|orf6.1851|CaO19.3140 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 1495702 1497057 + orf19.3139 1495702 1497057 1 1495702 1497057 1495860 1496978 orf19.10651|IPF3264.2|IPF18884.2|IPF3264|Contig4-3009_0005|orf6.1850|orf6.5876|CA3571|CaO19.3139 Predicted ORF in Assemblies 19, 20 and 21; increased transcription is observed upon benomyl treatment; oxidative stress-induced via Cap1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1497883 1499075 + orf19.3138 1497883 1499075 1 1497883 1499075 1497965 1498915 NOP1 orf19.10650|IPF24186.1|IPF3267.2|Contig4-3009_0002|orf6.5875|CA3570|CaO19.3138|CaO19.10650 Nucleolar protein; flucytosine induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1498957 1500697 - orf19.3136 1498957 1500697 1 1500697 1498957 1500473 1499097 orf19.10648|IPF24174.1|IPF3268.1|Contig4-3009_0001|orf6.5873|CA3569|CaO19.3136|USP1|CaO19.10648|IPF3268 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1500738 1502679 - orf19.3135 1500738 1502679 1 1502679 1500738 1502679 1500898 orf19.10647|IPF24165.1|IPF7802.2|Contig4-2579_0009|Contig4-3009_0026|orf6.5872|CA3568|CaO19.10647|CaO19.3135|IPF7804.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1502722 1503162 - orf19.3134 1502722 1503162 1 1503162 1502722 1503162 1502722 orf19.10646|IPF24213.1|IPF7804.1|Contig4-2579_0007|orf6.5871|CA3567|CaO19.3134|CaO19.10646|IPF7804.5f [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1506991 1509409 + orf19.3133 1506991 1509409 1 1506991 1509409 1507275 1509227 GUT2 orf19.10645|IPF24162.1|IPF7812.2|Contig4-2291_0005|orf6.5870|CA3566|CaO19.3133|CaO19.10645 Predicted ORF in Assemblies 19, 20 and 21; Plc1p-regulated; transcription is upregulated in both intermediate and mature biofilms [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1509602 1511792 + orf19.3132 1509602 1511792 1 1509602 1511792 1509771 1511651 orf19.10644|IPF24161.1|IPF7815.2|Contig4-2291_0002|Contig4-2291_0003|Contig4-2291_0004|orf6.5869|CA3565|CaO19.10644|MSC2|CaO19.3132 Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1511689 1513212 - orf19.3131 1511689 1513212 1 1513212 1511689 1513065 1511767 OYE32 orf19.10643|IPF7817|IPF24176.1|IPF7817.2|Contig4-2291_0001|orf6.5868|CA3564|OYE99|CaO19.3131|CaO19.10643 Protein of NAD(P)H oxidoreductase family; induced by nitric oxide, amphotericin B, oxidative stress (via Cap1p); increased transcription associated with MDR1 overexpression or benomyl treatment; macrophage-downregulated protein abundance [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1513816 1514817 + orf19.3130 1513816 1514817 1 1513816 1514817 1513945 1514766 orf19.10642|IPF24185.1|IPF7819.2|orf6.5867|CA3563|CaO19.3130|CaO19.10642|IPF7819 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1514920 1516370 + orf19.3129 1514920 1516370 1 1514920 1516370 1514961 1516337 orf19.10641|IPF24175.1|IPF7823.2|Contig4-2672_0010|orf6.5866|CA3562|RVB1|CaO19.10641|CaO19.3129|IPF7823 Predicted ORF in Assemblies 19, 20 and 21; heterozygous null mutant displays sensitivity to virgineone [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1516325 1518469 - orf19.3128 1516325 1518469 1 1518469 1516325 1518395 1516473 orf19.10640|IPF24164.1|IPF10610.2|Contig4-2672_0008|Contig4-2672_0009|orf6.5865|CA3561|CaO19.3128|SLY1|CaO19.10640 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1518656 1522389 - orf19.3127 1518656 1522389 1 1522389 1518656 1520318 1519161 CZF1 orf19.10639|ZNF1|IPF24182.1|IPF10612.2|Contig4-2672_0006|orf6.5864|CA3560|CaO19.3127|CaO19.10639 Transcriptional regulator of white-opaque switching frequency; hyphal growth regulator; has C-terminal zinc finger and central Glu-rich region; expression in S. cerevisiae causes dominant-negative inhibition of pheromone response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1527834 1529657 - orf19.3126 1527834 1529657 1 1529657 1527834 1529615 1527936 CCT6 orf19.10638|IPF24168.1|IPF14978.2|orf6.6919|CA4385|CaO19.10638|CaO19.3126 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to cytochalasin D [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1529748 1531068 + orf19.3125 1529748 1531068 1 1529748 1531068 1529815 1530591 orf19.10637|IPF12412|IPF24188.1|IPF12412.2|orf6.6920|CA4386|CaO19.3125|CaO19.10637 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1530400 1531837 - orf19.3124 1530400 1531837 1 1531837 1530400 1531744 1530629 orf19.10636|IPF24183.1|IPF12414.2|Contig4-2435_0009|orf6.6921|CA4387|CaO19.10636|MAP1|CaO19.3124 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1531857 1532697 - orf19.3123.2 1531857 1532697 4 1532697|1532489|1532386|1532204 1532560|1532453|1532272|1531857 1532638 1531992 IPF24159.1|IPF12416.1|CA4388|IPF12416.3f|IPF12416.3 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1532828 1534187 + orf19.3123 1532828 1534187 1 1532828 1534187 1532862 1534154 RPT5 orf19.10635|IPF24172.1|IPF12419.1|Contig4-2435_0006|orf6.6922|CA4389|CaO19.3123|CaO19.10635 Predicted ORF in Assemblies 19, 20 and 21; transcription is regulated by Nrg1p and Mig1p; regulated by Gcn2p and Gcn4p; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1534164 1534645 - orf19.3122.2 1534164 1534645 1 1534645 1534164 1534528 1534247 IPF24226.1|IPF12420.1|Contig4-2435_0005|CA4390|HOD1 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1535386 1536752 + orf19.3122 1535386 1536752 1 1535386 1536752 1535519 1536700 ARR3 orf19.10634|IPF24180.1|IPF12422.2|Contig4-2435_0003|orf6.6923|CA4391|CaO19.10634|CaO19.3122 Protein not essential for viability; similar to S. cerevisiae Arr3p, which is an arsenite transporter of the plasma membrane required for resistance to arsenic compounds; benomyl-induced; Gcn4p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1537009 1537746 + orf19.3121 1537009 1537746 1 1537009 1537746 1537009 1537746 GST1 orf19.10633|IPF24190.1|IPF12303.2|Contig4-2438_0010|orf6.6924|CA4392|CaO19.10633|CaO19.3121|IPF12303 Predicted ORF in Assemblies 19, 20 and 21; upregulated in the presence of human neutrophils; expression is regulated upon white-opaque switching; increased transcription is observed upon benomyl treatment [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 1538237 1539976 + orf19.3120 1538237 1539976 1 1538237 1539976 1538237 1539976 orf19.10632|IPF12299.2|IPF12300.1|Contig4-2438_0009|orf6.6925|CA4393|CaO19.10632|CaO19.3120|IPF12300 [NOT TRANSCRIBED?] Putative PDR-subfamily ABC transporter (half-size); similar to WHITE subfamily proteins; decreased transcription is observed upon fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2; induced by nitric oxide [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 1540131 1540574 - orf19.3117 1540131 1540574 1 1540574 1540131 1540574 1540131 CSA2 orf19.10631|IPF24214.1|IPF12297.1|Contig4-2438_0005|Contig4-2438_0006|Contig4-2438_0007|orf6.6928|orf6.6926|CA4394|orf19.3119|CaO19.10629|CRW1|CaO19.3117|IPF12297 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21; downregulated by Rim101p at pH 8; regulated by Tsa1p, Tsa1Bp in minimal media at 37 deg; induced by ketoconazole and nitric oxide [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 1541000 1542287 - orf19.3116 1541000 1542287 1 1542287 1541000 1542161 1541439 EXM2 orf19.10628|IPF24191.1|IPF12295.1|Contig4-2438_0002|orf6.6929|CA4395|CaO19.3116|LUC7|CaO19.10628 Decreased transcription is observed upon fluphenazine treatment [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1542380 1543771 - orf19.3115 1542380 1543771 1 1543771 1542380 1543724 1542558 orf19.10627|IPF24181.1|IPF12294.2|Contig4-2438_0013|orf6.6930|CA4396|CaO19.3115|CaO19.10627|IPF12294 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1543852 1544753 + orf19.3114 1543852 1544753 1 1543852 1544753 1543882 1544625 orf19.10626|IPF24189.1|IPF14369.2|Contig4-2739_0005|orf6.6931|CA4397|CaO19.10626|CaO19.3114|IPF14369 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1544757 1545407 + orf19.3113 1544757 1545407 1 1544757 1545407 1544911 1545339 orf19.10625|IPF24211.1|IPF14368.2|Contig4-2739_0004|orf6.6932|CaO19.3113|CaO19.10625 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1545396 1546802 - orf19.3112 1545396 1546802 1 1546802 1545396 1546802 1545396 ZRT1 orf19.10624|IPF24173.1|IPF14367.2|Contig4-2739_0003|orf6.6933|CA4398|CaO19.10624|CaO19.3112 Protein described as zinc transporter; hyphal- and macrophage-induced; alkaline upregulated by Rim101p; induced upon adherence to polystyrene [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 1547311 1548210 + orf19.3111 1547311 1548210 1 1547311 1548210 1547311 1548210 PRA1 orf19.10623|orf6.6934|FBP1|mp58|IPF8782.2|IPF14364.1|Contig4-2739_0001|orf6.60|CA4399|CaO19.3111 Cell surface protein, enriched at hyphal tips; also released extracellularly; binds to host complement regulators, integrin alphaMbeta2; mediates leukocyte adhesion; immunogenic in mouse; produced at ambient pH; Rim101p induced [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 1548566 1550906 + orf19.3110 1548566 1550906 1 1548566 1550906 1548772 1550850 orf19.10622|IPF14362.3|IPF8781.2|Contig4-2940_0015|orf6.61|orf6.6935|CA4400|MNN46|CaO19.3110|IPF14362 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1550992 1551618 + orf19.3109 1550992 1551618 1 1550992 1551618 1550992 1551618 orf19.10621|IPF24194.1|IPF8780.1|Contig4-2940_0014|orf6.6936|CA4401|CaO19.10621|CaO19.3109|IPF8780 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr4 1551129 1551368 - ntar_839 1551129 1551368 1 1551368 1551129 1551260 1551129 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1551493 1552374 - orf19.3108 1551493 1552374 1 1552374 1551493 1552167 1551640 orf19.10620|IPF24204.1|IPF8778.1|Contig4-2940_0013|orf6.6937|CA4402|CaO19.10620|MGT1|CaO19.3108 Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide in yhb1 mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1552441 1553152 - orf19.3107 1552441 1553152 1 1553152 1552441 1553136 1552690 orf19.10619|IPF24210.1|IPF8777.2|orf6.6938|CA4403|CaO19.10619|CaO19.3107|IPF8777 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr4 1553830 1554799 + orf19.3106 1553830 1554799 1 1553830 1554799 1553891 1554649 MET16 orf19.10618|IPF24192.1|IPF8775.2|Contig4-2940_0008|orf6.6939|CA4404|CaO19.10618|CaO19.3106 Putative 3'-phosphoadenylsulfate reductase; predicted enzyme of sulfur amino acid metabolism; reports differ on regulation during biofilm formation; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1554803 1556388 + orf19.3105 1554803 1556388 1 1554803 1556388 1554827 1556386 orf19.10617|IPF24169.1|IPF8773.2|Contig4-2940_0007|orf6.6940|CA4405|CaO19.3105|TRI4|CaO19.10617|IPF8773 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1556212 1556366 - ntar_840 1556212 1556366 1 1556366 1556212 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1556586 1557821 + orf19.3104 1556586 1557821 1 1556586 1557821 1556725 1557615 YDC1 orf19.10616|IPF24187.1|IPF8772.2|Contig4-2940_0005|orf6.6941|CA4406|CaO19.3104|CaO19.10616 Predicted ORF in Assemblies 19, 20 and 21; shows Mob2p-dependent hyphal regulation; transcription is regulated by Nrg1p and Mig1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1557938 1562402 + orf19.3103 1557938 1562402 1 1557938 1562402 1557984 1562330 orf19.10615|IPF24220.1|IPF13155.2|Contig4-2940_0002|Contig4-2940_0003|orf6.6942|CA4407|CaO19.3103|RPO3|RPO31 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1562446 1563198 + orf19.3102 1562446 1563198 1 1562446 1563198 1562457 1563098 CTA6 orf19.10614|IPF17498.2|IPF13152.2|Contig4-2121_0001|Contig4-2940_0001|orf6.148|orf6.6943|CA4408|CaO19.3102|CTA6.3 Predicted ORF in Assemblies 19, 20 and 21; activates transcription in 1-hybrid assay in S. cerevisiae; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1563096 1566351 - orf19.3100 1563096 1566351 1 1566351 1563096 1566260 1563144 orf19.10613|IPF17497.2|IPF13151.2|Contig4-2121_0002|Contig4-2121_0003|Contig4-2121_0004|orf6.149|orf6.415|orf6.6945|orf6.414|CA4409|CaO19.3100|IPF13151 Predicted ORF in Assemblies 19, 20 and 21; transcription is repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1566483 1568069 - orf19.3099 1566483 1568069 1 1568069 1566483 1567955 1566846 TRP4 orf19.10611|IPF19292.2|IPF1754.2|Contig4-2877_0001|orf6.416|orf6.6946|CA4410|CaO19.3099 Predicted enzyme of amino acid biosynthesis; upregulated in biofilm; regulated by Gcn2p and Gcn4p; S. cerevisiae ortholog is Gcn4p regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1568149 1574169 - orf19.3098 1568149 1574169 1 1574169 1568149 1574169 1568206 orf19.10610|IPF24199.1|IPF1751.2|Contig4-2877_0004|orf6.6947|CA4411|CaO19.10610|BRR2|CaO19.3098 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1568220 1568620 + ntar_841 1568220 1568620 1 1568220 1568620 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1574250 1575569 - orf19.3097 1574250 1575569 1 1575569 1574250 1575542 1574337 PDA1 orf19.10608|orf19.10609|IPF24178.1|IPF1749.1|Contig4-2877_0005|Contig4-2877_0006|orf6.6949|orf6.6948|CA4412|orf19.3096|CaO19.3097|CaO19.10609 Protein described as similar to alpha chain of pyruvate dehydrogenase; fluconazole-induced; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1575762 1578386 - orf19.3093 1575762 1578386 1 1578386 1575762 1578386 1575765 MSH2 orf19.10605|IPF24154.1|IPF1746.1|Contig4-2877_0007|orf6.6952|CA4413|CaO19.10605|CaO19.3093 Protein described as DNA mismatch repair factor; transcription is regulated by Nrg1p; flucytosine repressed; RNA abundance regulated by tyrosol and cell density [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1578601 1583031 + orf19.3091 1578601 1583031 1 1578601 1583031 1578626 1582930 orf19.10602|orf19.10603|IPF24217.1|IPF1742.3|Contig4-2877_0008|Contig4-2877_0009|Contig4-2877_0011|Contig4-2877_0013|orf6.3731|orf6.3730|orf6.6954|CA4414|orf19.3090|CaO19.3091|IPF1742|CA2008|IPF1742.3f.eoc|IPF1740.2 Predicted ORF in Assemblies 19, 20 and 21; downregulated during core stress response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1583175 1583849 + orf19.3089 1583175 1583849 1 1583175 1583849 1583217 1583801 orf19.10601|IPF24196.1|IPF1732.1|Contig4-2877_0015|orf6.3732|CA2009|CaO19.10601|CaO19.3089|IPF1732 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1584008 1584576 + orf19.3088 1584008 1584576 1 1584008 1584576 1584008 1584547 orf19.10600|IPF24201.1|IPF1731.2|orf6.3733|CA2010|CaO19.3088|CaO19.10600|IPF1731 Putative transcription factor with bZIP DNA-binding motif; induced upon biofilm formation; possibly transcriptionally regulated upon hyphal formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1584434 1585135 - orf19.3087.1 1584434 1585135 1 1585135 1584434 1584817 1584527 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1584645 1584888 + orf19.3087.2 1584645 1584888 1 1584645 1584888 1584675 1584854 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1585505 1586140 + orf19.3087 1585505 1586140 1 1585505 1586140 1585505 1586086 UBI3 orf19.10599|RPS31|IPF24198.1|IPF1727.2|Contig4-2594_0005|orf6.3734|CA2011|CaO19.3087|CaO19.10599 Fusion of ubiquitin with the S34 protein of the small ribosomal subunit; mRNA decreases upon heat shock, appears to be degraded; functional homolog of S. cerevisiae RPS31 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1586257 1588737 + orf19.3086 1586257 1588737 1 1586257 1588737 1586265 1588622 orf19.10598|IPF24157.1|IPF1725.2|Contig4-2594_0007|Contig4-2594_0009|orf6.3735|CA2012|CaO19.10598|SEC10|CaO19.3086 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1588591 1589827 - orf19.3083 1588591 1589827 1 1589827 1588591 1589817 1588615 orf19.10595|IPF24179.1|IPF1720.2|Contig4-2594_0010|orf6.3738|CA2013|CDC1|CaO19.3083|CaO19.10595 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1589876 1590891 + orf19.3084 1589876 1590891 1 1589876 1590891 1589891 1590772 orf19.10596|IPF24184.1|IPF1719.2|Contig4-2594_0011|orf6.3737|CaO19.10596|CaO19.3084 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1590674 1594024 - orf19.3080 1590674 1594024 1 1594024 1590674 1593905 1590765 IPF1717.2|IPF18927.2|Contig4-2594_0013|orf6.1637|orf6.3741|CA2014|CaO19.3080|IPF1717.3f|IPF1717 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1594473 1596561 - orf19.3077 1594473 1596561 1 1596561 1594473 1596561 1594501 VID21 orf19.10590|IPF18566.2|IPF1713.2|orf6.1634|orf6.3743|orf6.3744|CA0604|CaO19.3077 Subunit of the NuA4 histone acetyltransferase complex; soluble protein in hyphae [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr4 1596720 1597190 + orf19.3076 1596720 1597190 1 1596720 1597190 1596736 1597134 orf19.10588|IPF24209.1|IPF1709.2|orf6.1633|CA0603|CaO19.10588|CaO19.3076|IPF1709 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr4 1597337 1597996 - orf19.3074 1597337 1597996 1 1597996 1597337 1597996 1597337 TLO10 orf19.10586|IPF24195.1|IPF1708.2|Contig4-1846_0003|orf6.1631|CA0602|CTA211|CaO19.3074|CaO19.10586|CTA22 Member of a family of telomere-proximal genes of unknown function [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr4 1598558 1598857 + ntar_842 1598558 1598857 1 1598558 1598857 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1602107 1602858 + ntar_843 1602107 1602858 1 1602107 1602858 1602193 1602432 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr4 1603087 1603443 + orf19.3073 1603087 1603443 1 1603087 1603443 1603087 1603443 orf19.10585|IPF24227.1|IPF16712.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 1918 2677 + orf19.5700 1918 2677 1 1918 2677 1918 2427 TLO11 IPF5443.2|orf6.4578|CA2615|TLO11b|CaO19.5700|CTA224|CTA241.5f|CTA241.exon1 Member of a family of telomere-proximal genes of unknown function; may be spliced in vivo [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr5 3318 3872 - ntar_844 3318 3872 1 3872 3318 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 3876 4833 + orf19.5698 3876 4833 1 3876 4833 3999 4808 IPF5446.1|Contig4-2278_0006|orf6.4576|CA2613|CaO19.5698|MRPL1|IPF5446 Putative ribosomal protein, transcription is upregulated in clinical isolates from HIV+ patients with oral candidiasis; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 4791 6483 - orf19.5693 4791 6483 1 6483 4791 6473 4830 IPF5450.1|Contig4-2278_0008|Contig4-2278_0009|orf6.4571|CA2612|CaO19.5693|GAA1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 6406 7617 + ntar_845 6406 7617 1 6406 7617 6406 7230 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 7081 8830 - orf19.5692 7081 8830 1 8830 7081 8807 7209 IPF5453.1|Contig4-2927_0017|orf6.4570|CA2611|CaO19.5692|IPF5453 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 8929 10203 + orf19.5691 8929 10203 1 8929 10203 8946 10154 CDC11 IPF5456.1|Contig4-2927_0014|orf6.4569|CA2610|CaO19.5691 Septin; required for wild-type cell and hyphal morphology, agar-invasive growth, full virulence and kidney tissue invasion in mouse, but not for kidney colonization, immunogenicity; phosphorylation is hyphal- and cell-cycle-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 10083 11107 - orf19.5689 10083 11107 1 11107 10083 11086 10151 IPF5457.1|Contig4-2927_0013|orf6.4567|CA2609|CaO19.5689|IPF5457 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 11117 11819 - orf19.5688 11117 11819 1 11819 11117 11819 11157 orf6.4566|CaO19.5688 Predicted ORF from Assembly 19; removed from Assembly 20; subsequently reinstated in Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 11839 12441 - orf19.5686 11839 12441 1 12441 11839 12441 11839 IPF5460.1|Contig4-2927_0011|orf6.4564|CaO19.5686 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 11896 12405 + ntar_846 11896 12405 1 11896 12405 11896 12405 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 12554 14688 - orf19.5685 12554 14688 1 14688 12554 14674 12554 THS1 IPF5462.1|Contig4-2927_0010|orf6.4563|CA2608|CaO19.5685 Putative threonyl-tRNA synthetase; transcription regulated by Mig1p and Tup1p; downregulated upon phagocytosis by murine macrophages; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 14744 15099 + orf19.5684.1 14744 15099 1 14744 15099 14763 15059 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 15003 15478 - orf19.5684 15003 15478 1 15478 15003 15475 15077 IPF5464.1|Contig4-2927_0007|orf6.4562|CA2607|MRPL38|CaO19.5684 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 15515 16268 - orf19.5683 15515 16268 1 16268 15515 16255 15563 IPF5466.1|Contig4-2927_0006|orf6.4561|CA2606|CaO19.5683|IPF5466 Predicted ORF in Assemblies 19, 20 and 21; clade-associated gene expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr5 16326 18056 - orf19.5682 16326 18056 1 18056 16326 18029 16398 IPF5468.1|Contig4-2927_0004|orf6.4560|CA2605|SRP1|CaO19.5682 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 18123 18932 + orf19.5681 18123 18932 1 18123 18932 18148 18882 IPF5469.1|Contig4-2927_0002|orf6.4559|CA2604|CaO19.5681|IPF5469 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 18999 20131 + orf19.5680 18999 20131 1 18999 20131 19011 20093 IPF5471.1|Contig4-2927_0001|orf6.4558|CA2603|CaO19.5680|IPF5471 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 20218 23552 + orf19.980 20218 23552 1 20218 23552 20226 23504 orf19.8595|IPF5473.1|IPF26319.1|IPF1615.2|Contig4-3103_0056|orf6.8229|orf6.4557|CA2602|CA5427|orf19.5679|IPF1615.3eoc|VIP1|CaO19.8595|CaO19.980 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr5 23492 29785 - orf19.979 23492 29785 1 29785 23492 29661 23548 FAS1 orf19.8594|Contig4-3103_0003|Contig4-3103_0006|Contig4-3103_0007|Contig4-3103_0008|IPF1611.2|orf6.8228|CA5426|CaO19.8594|CaO19.979 Beta subunit of fatty-acid synthase; multifunctional enzyme; fluconazole-induced; amphotericin B, caspofungin repressed; macrophage/pseudohyphal-induced; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 30683 33146 - orf19.978 30683 33146 1 33146 30683 32918 30720 BDF1 orf19.8593|orf6.8227|IPF26320.1|IPF1604.2|Contig4-3103_0010|Contig4-3103_0011|CA5425|CaO19.978|CaO19.8593 Putative transcription factor; downregulated upon adherence to polystyrene; reduced mRNA abundance detected in homozygous fkh2 null mutant; macrophage/pseudohyphal-repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr5 33488 33906 + ntar_847 33488 33906 1 33488 33906 33594 33767 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 33735 36517 - orf19.976 33735 36517 1 36517 33735 35884 33839 BRE1 orf19.8591|IPF26322.1|IPF1598.2|Contig4-3103_0012|orf6.8225|CA5424|CaO19.976|CaO19.8591|IPF1598 Putative transcription factor with C3HC4 zinc finger DNA-binding motif; similar to S. cerevisiae Bre1p; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 36656 39407 + orf19.974 36656 39407 1 36656 39407 36656 39271 ROT2 orf19.8589|GLS2|IPF26310.1|IPF1591.1|Contig4-3103_0013|orf6.8223|CA5423|CaO19.974|CaO19.8589 Alpha-glucosidase II, catalytic subunit, required for N-linked protein glycosylation and normal cell wall synthesis; alkaline downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr5 38732 40161 - orf19.972 38732 40161 1 40161 38732 40126 39266 orf19.8587|IPF26339.1|IPF1588.1|Contig4-3103_0014|orf6.8221|CA5422|CaO19.972|SLX1|CaO19.8587|IPF1588 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 40779 42793 + orf19.971 40779 42793 1 40779 42793 40891 42570 SKN7 orf19.8586|IPF26326.1|IPF1586.1|Contig4-3103_0018|orf6.8220|CA5421|CaO19.8586|CaO19.971 Putative homolog of S. cerevisiae Skn7p, which is predicted to be a response regulator protein in a phosphorelay signal transduction pathway [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 42486 43255 - orf19.970 42486 43255 1 43255 42486 43190 42567 orf19.8585|IPF26344.1|IPF1583.1|Contig4-3103_0019|orf6.8219|CA5420|CaO19.8585|CaO19.970|IPF1583 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 43370 44721 + orf19.969 43370 44721 1 43370 44721 43421 44635 orf19.8584|PRS1|IPF26333.1|IPF1582.1|Contig4-3103_0021|orf6.8218|CA5419|CaO19.969|PRS11|CaO19.8584 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 45796 46373 + orf19.968 45796 46373 1 45796 46373 45823 46218 PGA14 orf19.8583|IPF26359.1|IPF1580.1|Contig4-3103_0023|orf6.8217|CA5418|CaO19.968|CaO19.8583|IPF1580 Putative GPI-anchored protein of unknown function; induced during cell wall regeneration; regulated by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 46334 47392 - orf19.967 46334 47392 1 47392 46334 47366 46404 orf19.8582|IPF26338.1|IPF1578.1|Contig4-3103_0024|orf6.8216|CA5417|NUC1|CaO19.8582|CaO19.967 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 47730 48948 + orf19.966 47730 48948 1 47730 48948 47854 48873 orf19.8581|IPF26336.1|IPF1576.1|Contig4-3103_0028|orf6.8215|CA5416|CaO19.966|DUS4|CaO19.8581|IPF1576 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 48787 53041 - orf19.964 48787 53041 1 53041 48787 53010 48904 SMC4 orf19.8579|IPF26364.1|IPF1574.1|Contig4-3103_0030|orf6.8213|CA5415|CaO19.964|CaO19.8579 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 53141 53846 - orf19.962 53141 53846 1 53846 53141 53780 53247 orf19.8577|IPF26352.1|IPF1568.1|Contig4-3103_0031|Contig4-3103_0032|orf6.8211|CA5414|CBF5|CaO19.962|CaO19.8577|IPF1568 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 53981 54535 + orf19.961.2 53981 54535 1 53981 54535 54029 54322 IPF26366.1|IPF1567.1|Contig4-3103_0033|CA5413|IPF1567 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 54335 63318 - orf19.956 54335 63318 1 63318 54335 63318 54415 orf19.8571|IPF26341.1|IPF1566.1|Contig4-3103_0034|orf6.8205|CA5412|CSF1|CaO19.956|CaO19.8571|IPF1566 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr5 63649 64670 + orf19.955 63649 64670 1 63649 64670 63667 64644 orf19.8570|IPF26337.1|IPF1558.1|Contig4-3103_0035|orf6.8204|CA5411|CaO19.8570|CaO19.955|IPF1558 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 64613 66202 - orf19.954 64613 66202 1 66202 64613 66052 64733 orf19.8569|IPF26331.1|IPF1557.1|Contig4-3103_0037|orf6.8203|CA5410|XDJ1|CaO19.954|CaO19.8569|IPF1557 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 66383 66464 - ts(cag)1 66383 66464 1 66464 66383 tS(CAG)1.2 tRNA-Ser predicted by tRNAscan-SE; responsible for the decoding of CUG as Ser, rather than the usual Leu; more similar to other Ser tRNAs than to Leu tRNAs in hemiascomycetes; has atypical G at position 33 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 67544 68619 + orf19.953.1 67544 68619 3 67544|67736|67850 67607|67746|68619 67605 68261 COF1 IPF26361.1|IPF1554.1|Contig4-3103_0038|CA5409|COF1.3f Protein described as cofilin; macrophage-induced protein; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 69038 71428 + orf19.952 69038 71428 1 69038 71428 69038 71404 orf19.8567|IPF26314.1|IPF1551.1|Contig4-3103_0039|orf6.8201|CA5408|CaO19.952|CaO19.8567|IPF1551 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr5 71401 72420 - orf19.951 71401 72420 1 72420 71401 72101 71613 orf19.8566|IPF26348.1|IPF1548.1|Contig4-3103_0040|orf6.8200|CA5407|CaO19.8566|CaO19.951|IPF1548 Predicted ORF in Assemblies 19, 20 and 21; transcription downregulated upon yeast-hyphal switch; fluconazole-induced; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 73190 73960 + ntar_848 73190 73960 1 73190 73960 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 73517 73660 - ntar_849 73517 73660 1 73660 73517 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 73807 76764 - orf19.949 73807 76764 1 76764 73807 76453 74018 orf19.8564|IPF26315.1|IPF1547.1|Contig4-3103_0044|orf6.8198|CA5406|TPM1|CaO19.949|CaO19.8564|IPF1547 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 77014 77597 + orf19.948 77014 77597 1 77014 77597 77014 77355 orf19.8563|IPF26360.1|IPF29626.1|Contig4-3103_0045|orf6.8197|CaO19.8563|CaO19.948 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr5 77391 78316 - orf19.947 77391 78316 1 78316 77391 78136 77777 MRP17 orf19.8562|IPF26371.1|IPF1544.1|Contig4-3103_0047|orf6.8196|CA5405|CaO19.947|CaO19.8562 Predicted mitochondrial ribosomal protein [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 78806 79521 + orf19.946 78806 79521 1 78806 79521 78890 79492 MET14 orf19.8561|IPF26346.1|IPF1543.1|Contig4-3103_0048|orf6.8195|CA5404|CaO19.946|CaO19.8561 Predicted ORF in Assemblies 19, 20 and 21; predicted role in sulfur metabolism; induced upon biofilm formation; possibly adherence-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 79413 80287 - orf19.945 79413 80287 1 80287 79413 80225 79518 VPS2 orf19.8560|IPF26342.1|IPF1542.1|Contig4-3103_0049|orf6.8194|CA5403|CaO19.8560|DID4|CaO19.945|IPF1542 Protein similar to S. cerevisiae Did4p/Vps2p, which is a member of the ESCRT III complex [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 80435 80670 + ntar_850 80435 80670 1 80435 80670 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 80438 81624 - orf19.944 80438 81624 2 81624|81503 81576|80438 81598 80483 IFG3 orf19.8559|IPF26335.1|IPF1541.1|Contig4-3103_0050|orf6.8193|CA5402|IFG3.3 Putative D-amino acid oxidase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 80921 81121 + ntar_851 80921 81121 1 80921 81121 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 81964 84097 - orf19.943 81964 84097 1 84097 81964 83979 82117 FET33 orf19.8558|IPF26325.1|IPF1540.2|Contig4-3103_0051|Contig4-3103_0052|orf6.8192|CA5401|FET397|CaO19.8558|CaO19.943|FET35.3 Putative multicopper ferro-O2-oxidoreductase; downregulated in core caspofungin response; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 84369 86237 - orf19.942 84369 86237 1 86237 84369 86237 84369 KRE62 orf19.8557|IPF26313.1|IPF26324.1|IPF1539.1|IPF1538.2|Contig4-3103_0054|orf6.8191|KRE62.5f|KRE62.3f|orf19.942.1|CA5399|CA5400 [NOT TRANSCRIBED?] Protein described as subunit of glucan synthase; macrophage-induced gene [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 86896 88374 - orf19.941 86896 88374 1 88374 86896 88250 87345 SEC14 orf19.8556|IPF26340.1|IPF9666.1|orf6.8190|CA5398|CaO19.941|CaO19.8556 Essential protein; functional homolog of S. cerevisiae Sec14p, which is a Golgi phosphatidylinositol/phosphatidylcholine transfer protein that regulates choline-phosphate cytidyltransferase and thereby affects secretion; biofilm-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 89742 93931 - orf19.940 89742 93931 1 93931 89742 93594 89881 BUD2 orf19.8555|orf6.8189|IPF26369.1|IPF9663.2|Contig4-2510_0003|CA5397|CaO19.940|CaO19.8555|IPF9663 GTPase activating protein (GAP) for Rsr1p; negative regulator of filament branching, acts in hyphal growth guidance; required for wild-type budding pattern; expression greater in low iron; regulated by tyrosol and cell density [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 94220 94405 + ntar_852 94220 94405 1 94220 94405 94239 94394 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 94236 94392 - ntar_853 94236 94392 1 94392 94236 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 94623 98212 + orf19.939 94623 98212 1 94623 98212 95043 98102 NAM7 orf19.8554|IPF26374.1|IPF9662.2|Contig4-2612_0009|orf6.8188|CA5396|CaO19.939|CaO19.8554 Putative role in nonsense-mediated mRNA decay; similar to S. cerevisiae Nam7p; gene induced by ciclopirox olamine treatment [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 103064 104752 + orf19.938 103064 104752 1 103064 104752 103156 104601 orf19.8553|IPF26329.1|IPF9401.1|Contig4-2726_0005|orf6.8187|CA5395|CaO19.8553|Gal11|CaO19.938|IPF9401 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr5 105031 105504 + orf19.937 105031 105504 1 105031 105504 105031 105504 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 105170 107921 - ntar_854 105170 107921 1 107921 105170 106663 106487 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 105626 107950 + orf19.936 105626 107950 1 105626 107950 105626 107950 orf19.8551|IPF26316.1|IPF9398.1|Contig4-2726_0007|Contig4-2726_0009|orf6.8185|CA5393|ASM2|CaO19.8551|CaO19.936|IPF9398 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 109765 111126 - orf19.935 109765 111126 1 111126 109765 110891 109830 AGA1 orf19.8550|IPF26334.1|IPF10571.2|Contig4-2870_0012|orf6.8184|CA5392|CaO19.935|CaO19.8550|IPF10571 Protein with some similarity to agglutinin subunit; expression is regulated upon white-opaque switching [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 121163 121965 - orf19.934 121163 121965 1 121965 121163 121859 121536 orf19.8549|IPF6528.1|Contig4-2870_0002|orf6.8183|orf6.1317|CA5391|orf19.2224|CaO19.8549|CaO19.934|IPF18109|IPF18109.1 Predicted ORF from Assembly 19; removed from Assembly 20; subsequently reinstated in Assembly 21 and merged with orf19.2224, based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 122118 123019 + orf19.933 122118 123019 1 122118 123019 122294 122803 orf19.8548|IPF6529.2|IPF26349.1|IPF29623.1|Contig4-2870_0001|orf6.8182|orf6.1318|CA0417|orf19.2225|UBC13|CaO19.933|CaO19.8548 Predicted ORF in Assemblies 19, 20 and 21; merged with orf19.2225 in Assembly 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 124142 124289 + ntar_855 124142 124289 1 124142 124289 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 124819 130402 + orf19.932 124819 130402 1 124819 130402 125118 130268 orf19.8547|IPF18993.1|IPF26353.1|IPF6532.2|Contig4-2777_0010|orf6.8181|orf6.1319|CA5390|orf19.2226|DRS24|CaO19.932|DNF2|CaO19.8547 Predicted ORF in Assemblies 19, 20 and 21; merged with orf19.2226 in Assembly 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr5 130581 133041 + orf19.931 130581 133041 1 130581 133041 130828 132912 orf19.8546|IPF26321.1|IPF6533.2|Contig4-2777_0005|Contig4-2777_0008|orf6.8180|CA5389|CaO19.8546|LPF6|CaO19.931|IFA13 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 134669 135746 + orf19.930 134669 135746 1 134669 135746 134740 135645 PET9 orf19.8545|IPF6536.2|IPF29622.1|Contig4-2777_0002|orf6.8179|CA5388|CaO19.930|CaO19.8545 Protein involved in ATP biosynthesis; identified in detergent-resistant membrane fraction (possible lipid raft component); 3 predicted transmembrane helices; flucytosine induced; ketoconazole-induced; downregulated by Efg1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 137597 138904 - orf19.929 137597 138904 1 138904 137597 138904 137597 orf19.8544|IPF26332.1|IPF8420.2|Contig4-2136_0001|orf6.2859|CA1381|CaO19.929|CaO19.8544|IPF8420 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr5 139365 141500 - orf19.928 139365 141500 1 141500 139365 141377 139515 orf19.8543|IPF26323.1|IPF8421.2|Contig4-2136_0006|orf6.2860|CA1382|CaO19.928|CaO19.8543|IPF8421 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 141581 142402 + orf19.927 141581 142402 1 141581 142402 141659 142270 orf19.8542|IPF26343.1|IPF8422.2|Contig4-2136_0007|orf6.2861|CA1383|CaO19.8542|CaO19.927|IPF8422 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 142185 144477 - orf19.926 142185 144477 1 144477 142185 144424 142325 EXO1 orf19.8541|IPF26317.1|IPF8423.2|Contig4-2692_0013|orf6.2862|CA1384|CaO19.8541|CaO19.926|IPF8423 Predicted ORF in Assemblies 19, 20 and 21; cell-cycle regulated periodic mRNA expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 144701 146384 - orf19.925 144701 146384 1 146384 144701 146292 144766 orf19.8540|IPF26328.1|IPF8424.1|Contig4-2692_0012|orf6.2863|CA1385|CaO19.8540|CaO19.925|IPF8424 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 146570 147836 - orf19.923 146570 147836 1 147836 146570 147787 146714 THR1 orf19.8539|IPF19445.1|IPF8426.1|Contig4-2692_0010|orf6.2865|orf6.99|CA1386|CaO19.923 Putative homoserine kinase; fungal-specific (no human or murine homolog); transcription is regulated by Tup1p; amphotericin B repressed; regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 147987 149835 - orf19.922 147987 149835 1 149835 147987 149706 148120 ERG11 orf19.8538|ERG16|CYP51|P45014DM|orf6.98|orf6.1245|L1A1|IPF19860.2|IPF8427.2|Contig4-2692_0009|orf6.2866|CA1387|CaO19.922 Lanosterol 14-alpha-demethylase, member of cytochrome P450 family that functions in ergosterol biosynthesis; target of azole antifungals; may contribute to drug resistance; azole- or biofilm-induced; subject to hypoxic regulation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 150338 151105 + ntar_856 150338 151105 1 150338 151105 150338 150583 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 151085 153342 - orf19.921 151085 153342 1 153342 151085 153233 151176 orf19.8536|IPF16514.3|Contig4-2692_0006|orf6.1243|orf6.2867|CA1388|CaO19.921|IPF16514|IPF16514.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 153473 154142 - ntar_857 153473 154142 1 154142 153473 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 156769 158474 + orf19.920 156769 158474 1 156769 158474 156807 158162 RMT2 orf19.8535|IPF19012.2|IPF16809.2|Contig4-2402_0003|orf6.1242|orf6.571|CA0119|RMT2.5eoc Minor protein arginine methyltransferases (PRMT) involved in methylation of arginine residues [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 157377 159369 - orf19.567 157377 159369 2 159369|159251 159312|157377 159330 158188 TFB3 orf19.8198|IPF18427.2|IPF11571.2|Contig4-2182_0001|orf6.372|orf6.4717|CA2711|CaO19.567|IPF18427.1 Putative transcription factor with C3HC4 zinc finger DNA-binding motif; transcription is positively regulated by Tbf1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 159434 161141 - orf19.568 159434 161141 1 161141 159434 160775 159627 SPE2 orf19.8199|IPF11572.1|IPF19320.2|Contig4-2182_0003|orf6.371|orf6.4718|CA2712|CaO19.568 Predicted ORF in Assemblies 19, 20 and 21; possibly adherence-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 164521 166665 + orf19.570 164521 166665 1 164521 166665 164521 166665 IFF8 orf19.8201|Contig4-2860_0006|IPF26693.1|IPF11578.2|orf6.4720|CA2713|CaO19.8201|CaO19.570 Putative GPI-anchored protein of unknown function; decreased transcription is observed in an azole-resistant strain that overexpresses MDR1 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr5 171037 175167 + orf19.575 171037 175167 1 171037 175167 171037 174786 HYR3 orf19.8206|IFF2|orf6.4725|IPF26737.1|IPF7360.1|Contig4-2857_0004|CA2714|CaO19.575|CaO19.8206 Putative GPI-anchored protein of unknown function; similar to Hyr1p; transcriptionally regulated by iron; expression greater in high iron; clade-specific repeat variation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr5 175114 175351 - ntar_858 175114 175351 1 175351 175114 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 175472 176156 + orf19.576 175472 176156 1 175472 176156 175559 176047 CTF8 orf19.8207|IPF26720.1|IPF7354.1|Contig4-2857_0006|orf6.4726|CA2715|CaO19.8207|CaO19.576 Protein repressed during the mating process [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 175995 178281 - orf19.577 175995 178281 1 178281 175995 178140 176158 orf19.8208|IPF26695.1|IPF7353.2|Contig4-2857_0007|orf6.4727|CA2716|CaO19.577|CaO19.8208|IPF7353 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 179258 179603 - ntar_859 179258 179603 1 179603 179258 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 179811 181962 + orf19.578 179811 181962 1 179811 181962 180051 181865 orf19.8209|IPF7351.2|IPF29765.1|Contig4-2857_0008|orf6.467|orf6.4728|CA2717|MSB3|CaO19.578 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 181868 184412 - orf19.579 181868 184412 1 184412 181868 184282 181916 FOL1 orf19.8210|IPF6397.3|IPF7349.2|Contig4-2857_0009|orf6.1108|orf6.466|orf6.4729|CA0088|CaO19.579|IPF7349 Putative dihydroneopterin aldolase (dihydro-6-hydroxymethylpterin pyrophosphokinase); fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 184565 185903 - orf19.580 184565 185903 1 185903 184565 185859 184672 orf19.8211|IPF6396|IPF6396.2|IPF7348.3|Contig4-2778_0001|orf6.1109|orf6.465|CA0312|CaO19.580|CaO19.8211 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr5 185998 188909 - orf19.581 185998 188909 1 188909 185998 188241 186145 orf19.8214|IPF19045.1|IPF6394.1|Contig4-2778_0002|orf6.1110|orf6.1112|orf6.5699|CA3436|CaO19.581|NRD1 Putative protein of unknown function, transcription is upregulated in an RHE model of oral candidiasis; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 189085 190843 - orf19.583 189085 190843 1 190843 189085 190840 189518 orf19.8215|IPF26707.1|IPF6391.1|Contig4-2778_0003|orf6.5697|CA3435|CaO19.583|IPF6391 Putative indoleamine 2,3-dioxygenase (IDO); IDO is the rate-limiting enzyme of tryptophan catabolism via kynurenine pathway; enzyme inhibition by 1-methyl-D,L-tryptophan causes increased hyphal growth; expressed in yeast-form cells and hyphae [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 190894 191769 - orf19.584 190894 191769 1 191769 190894 191769 190894 orf19.8216|IPF26714.1|IPF6390.1|Contig4-2778_0005|orf6.5696|CA3434|CaO19.8216|CCP2|CaO19.584|CCP1 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 192388 193776 - ntar_860 192388 193776 1 193776 192388 193413 193252 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 192507 192635 + ntar_861 192507 192635 1 192507 192635 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 194301 195325 + orf19.585 194301 195325 1 194301 195325 194352 195203 orf19.8217|IPF26717.1|IPF20133.1|Contig4-2778_0007|orf6.5695|CA3432|CaO19.585|MRPL17|CaO19.8217 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 195215 196659 - orf19.586 195215 196659 1 196659 195215 196621 195377 ERV46 orf19.8218|IPF26709.1|IPF6383.2|Contig4-2633_0002|orf6.5694|CA3431|CaO19.8218|CaO19.586|FUN9 Transcription is induced upon filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 196724 198018 + orf19.587 196724 198018 1 196724 198018 196724 197917 orf19.8219|orf19.9539|IPF25380.1|IPF18752.2|IPF26708.1|IPF6382.1|Contig4-2633_0004|orf6.5693|orf6.2477|CA3430|orf19.1983|CaO19.587|CaO19.8219|IPF6382 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr5 197848 198472 - orf19.588 197848 198472 1 198472 197848 198313 197996 orf19.8220|orf19.9538|IPF25393.1|IPF8700.2|IPF6380.1|Contig4-2633_0005|orf6.2478|orf6.5692|CA3429|orf19.1982|CaO19.9538|CaO19.1982|CaO19.588|CaO19.8220|IPF6380 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 198571 199331 + orf19.1981 198571 199331 1 198571 199331 198650 199138 orf19.9537|IPF25384.1|IPF8699.2|Contig4-2554_0006|orf6.2479|CA1135|IMP2|CaO19.1981|CaO19.9537 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 199431 201150 - orf19.1980 199431 201150 1 201150 199431 201150 199552 GIT4 orf19.9536|IPF25367.1|IPF8698.2|Contig4-2554_0005|orf6.2480|CA1136|CaO19.9536|CaO19.1980|IFN2 Putative glycerophosphoinositol permease; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr5 202497 204453 - orf19.1979 202497 204453 1 204453 202497 204210 202603 GIT1 orf19.9535|IPF25363.1|IPF8694.2|IFN1|Contig4-2554_0002|orf6.2481|GIT3|CA1137|CaO19.1979|CaO19.9535 Putative glycerophosphoinositol permease; fungal-specific (no human or murine homolog); alkaline downregulated; transcription is specific to white cell type; caspofungin repressed; macrophage/pseudohyphal-repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 206321 208211 - orf19.1978 206321 208211 1 208211 206321 207953 206349 GIT2 orf19.9534|IPF18978.2|IPF8692.2|orf6.2482|CA1138|CaO19.1978|IFN3 Putative glycerophosphoinositol permease; fungal-specific (no human or murine homolog); transcription is repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr5 210128 211315 - orf19.1977 210128 211315 1 211315 210128 211286 210210 URA4 orf19.9533|IPF25375.1|IPF8687.1|Contig4-2794_0005|orf6.1407|CA0466|CaO19.9533|CaO19.1977 Predicted ORF in Assemblies 19, 20 and 21; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 211440 212515 - orf19.1976 211440 212515 1 212515 211440 211966 211610 TRX2 orf19.9532|IPF25391.1|IPF8686.2|Contig4-2794_0006|orf6.1408|CA0467|CaO19.1976|CaO19.9532 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 212431 213136 + orf19.1975 212431 213136 1 212431 213136 212577 213023 orf19.9531|IPF8685.2|IPF29250.1|Contig4-2794_0008|orf6.1409|CA0468|DIB1|CaO19.1975|CaO19.9531 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 212977 214059 - orf19.1974 212977 214059 1 214059 212977 213880 213101 TFS1 orf19.9530|IPF8684.2|IPF6281.2|Contig4-2794_0009|orf6.1410|orf6.1861|CA0748|CaO19.1974|IPF6281.1 Transcription is regulated upon yeast-hyphal switch; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 214450 215664 - orf19.1973 214450 215664 1 215664 214450 215592 214546 HAP5 orf19.9529|IPF25373.1|IPF6283.2|Contig4-2794_0012|orf6.1862|CA0749|CaO19.9529|CaO19.1973 Component of CCAAT-binding transcription factor; roles in filamentous growth, low-iron (chelation) induction of FRP1 transcription; regulates genes with roles in respiratory growth; functional homolog of S. cerevisiae Hap5p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 215777 217313 - orf19.1972 215777 217313 1 217313 215777 217288 215867 orf19.9528|IPF25370.1|IPF6284.1|Contig4-2794_0013|orf6.1863|CA0750|CaO19.9528|SET5|CaO19.1972|IPF6284 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 217462 217555 + te(uuc)4 217462 217555 2 217462|217521 217498|217555 tE(UUC)4.2 tRNA-Glu predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 217569 217662 + te(uuc)3 217569 217662 2 217569|217628 217605|217662 tE(UUC)3.2 tRNA-Glu predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 217958 219767 + orf19.1971 217958 219767 1 217958 219767 218221 219705 orf19.9527|IPF25369.1|IPF6286.2|Contig4-2794_0015|orf6.1864|CA0751|CaO19.1971|CaO19.9527|IPF6286 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 220212 220283 + tq(cug)1 220212 220283 1 220212 220283 tQ(CUG)1.2 tRNA-Gln predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 220314 221291 - orf19.1970 220314 221291 1 221291 220314 221192 220488 orf19.9526|IPF18882.2|IPF6289.1|Contig4-2813_0019|orf6.5034|CA2941|CaO19.1970|CVB1|CaO19.9526 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 221441 223060 - orf19.1968.1 221441 223060 1 223060 221441 222946 222671 IPF25390.1|IPF6293.1|Contig4-2813_0014|CA2943|MAK31 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 221848 222663 + orf19.1969 221848 222663 1 221848 222663 221848 222663 CCW14 orf19.9525|IPF6292.2|IPF6291.1|Contig4-2813_0016|orf6.5035|CA2942|CaO19.9525|CaO19.1969|IPF6291 [NOT TRANSCRIBED?] Putative mannoprotein of cell wall with role in response to stress; increased mRNA abundance observed in cyr1 homozygous mutant (hyphal or yeast-form cells) and in ras1 homozygous mutant (yeast-form cells) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 223144 223985 + orf19.1968 223144 223985 1 223144 223985 223459 223869 orf19.9524|IPF25386.1|IPF6294.1|Contig4-2813_0012|orf6.5036|CA2944|CaO19.1968|CaO19.9524|IPF6294 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr5 223858 224576 - orf19.1967 223858 224576 2 224576|224401 224466|223858 224544 223938 orf19.9523|IPF25383.1|IPF6295.1|Contig4-2813_0011|orf6.5037|CA2945|CaO19.9523|IMG1|CaO19.1967 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 224756 225667 - orf19.1966 224756 225667 1 225667 224756 225614 224799 BUD23 orf19.9522|IPF25379.1|IPF6296.2|Contig4-2813_0010|orf6.5038|CA2946|CaO19.9522|CaO19.1966|IPF6296 Predicted ORF in Assemblies 19, 20 and 21; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 225791 227551 - orf19.1964 225791 227551 1 227551 225791 227465 225963 orf19.9520|IPF25368.1|IPF6298.2|IPF6298|Contig4-2813_0008|orf6.5040|CA2947|AQR1|CaO19.1964|CaO19.9520 Putative protein of unknown function; downregulated upon fluphenazine treatment; upregulated upon benomyl treatment and in an RHE model; regulated by Nrg1p, Tup1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 228203 228460 + ntar_862 228203 228460 1 228203 228460 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 228700 229403 + ntar_863 228700 229403 1 228700 229403 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 229296 233433 - orf19.1963 229296 233433 2 233433|232472 233105|229296 231072 229549 orf19.9519|IPF25364.1|IPF6301.2|Contig4-2813_0004|orf6.5041|CA2948|CaO19.9519|GDS1|CaO19.1963 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr5 234684 236608 - orf19.1961 234684 236608 1 236608 234684 236456 234864 orf19.9516|IPF14506.1|IPF11296.1|Contig4-2193_0003|orf6.2315|orf6.5044|CA2949|CaO19.1961|IPF14506 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 243409 246451 - orf19.1960 243409 246451 1 246451 243409 245611 244214 CLN3 orf19.9515|CLN2|IPF10874.1|IPF11287.3|Contig4-2487_0005|orf6.2316|orf6.5045|CA2950|CaO19.1960 G1 cyclin; depletion causes abolished budding and hyphal growth defects; likely to be essential; farnesol regulated, upregulated in biofilm; functional in S. cerevisiae; similar to S. cerevisiae Cln3p, which is a G1-specific cyclin [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 251114 251296 - ntar_864 251114 251296 1 251296 251114 251296 251114 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 251150 251375 + ntar_865 251150 251375 1 251150 251375 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 253081 254608 + orf19.1959 253081 254608 1 253081 254608 253350 254321 orf19.9514|IPF25377.1|IPF15485.2|Contig4-2473_0003|orf6.4080|CA2253|CaO19.9514|CaO19.1959|IPF15485 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 254747 255256 + orf19.1958 254747 255256 1 254747 255256 254747 255256 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 256517 256770 - ntar_866 256517 256770 1 256770 256517 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 256877 257149 + ntar_867 256877 257149 1 256877 257149 256963 257097 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 261735 262810 + orf19.1957 261735 262810 1 261735 262810 261888 262682 CYC3 orf19.9512|orf6.4082|IPF14754.1|IPF13303.1|Contig4-2143_0003|orf6.343|CA2255|CaO19.1957 Cytochrome c heme lyase, mitochondrial; gene also encodes antigenic cell-wall protein; mRNA more abundant in filaments than yeast-form; induced on polystyrene adherence, interaction with macrophage; N-glycosylation, 2 heme-binding motifs [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 262719 265199 - orf19.1956 262719 265199 1 265199 262719 265067 262806 orf19.9511|IPF19331.2|IPF14757.2|Contig4-2143_0002|orf6.342|orf6.4083|CA2256|CaO19.1956|IPF14757 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 265210 265693 - ntar_1424 265210 265693 2 265693|265373 265633|265210 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 265956 266931 + orf19.1955 265956 266931 2 265956|266780 266705|266931 266079 266809 orf19.9510|IPF16837.1|IPF14758.2|Contig4-2077_0002|Contig4-2143_0001|orf6.4084|orf6.914|CA2257|SHR5|CaO19.1955 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 266976 268136 + orf19.1954 266976 268136 1 266976 268136 266976 268136 PUS4 orf19.9509|IPF16835.2|IPF12142.3|Contig4-2077_0003|orf6.1980|orf6.915|CA0221|CaO19.1954 Transcription is regulated by Nrg1p, Mig1p, and Tup1p [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 268278 269390 + orf19.1953 268278 269390 1 268278 269390 268278 269390 orf19.9508|IPF12141|IPF12141.1|IPF18863.1|IPF16834.2|Contig4-2077_0004|orf6.1978|orf6.916|orf6.1979|CA0222|orf19.1952|CA6266|IPF12141.5f|CaO19.1953 Predicted ORF in Assemblies 19, 20 and 21; not essential for viability; merged with orf19.1952 in Assembly 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 269484 270009 + orf19.1950 269484 270009 1 269484 270009 269484 269954 orf19.9506|IPF12138.1|IPF18864.1|Contig4-2077_0005|Contig4-2375_0009|orf6.1976|orf6.918|CA0820|CaO19.1950|IPF12138 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 269578 269773 - ntar_868 269578 269773 1 269773 269578 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 270250 272504 + orf19.1949 270250 272504 1 270250 272504 270302 272383 VPS1 orf19.9505|IPF19611.2|IPF19610.1|Contig4-2375_0001|Contig4-2375_0005|orf6.1975|orf6.919|CA0819|CaO19.1949 Protein described as a dynamin-family GTPase-related protein; induced upon adherence to polystyrene; regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 272509 272675 - ntar_869 272509 272675 1 272675 272509 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 272970 274481 + orf19.1948 272970 274481 1 272970 274481 273059 274360 orf19.9504|IPF25376.1|IPF12135.2|Contig4-2375_0006|orf6.1974|orf6.5591|CA0818|CaO19.1948|IPF12135|CA3351|IPF18347|IPF18347.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 274387 275437 - orf19.1946 274387 275437 1 275437 274387 275380 274481 orf19.9501|IPF16195.1|IPF16194.2|Contig4-1970_0003|orf6.1972|orf6.5593|CA3352|CaO19.1946|IPF16194 Similar to an aldose 1-epimerase-related protein; antigenic during murine systemic infection; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 276577 278842 + orf19.1945 276577 278842 1 276577 278842 277008 278423 AUR1 orf19.9500|IPF11286.2|IPF18866.2|Contig4-2985_0028|orf6.1971|orf6.5594|CA3353|CaO19.1945 Inositolphosphorylceramide (IPC) synthase, catalyzes the key step in the synthesis of sphingolipids; target for antifungal drugs; mutation confers hypersensitivity to aureobasidin A [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 280543 283500 + orf19.1944 280543 283500 1 280543 283500 280836 283307 GPR1 orf19.9499|IPF11281.2|IPF29241.1|Contig4-2985_0021|Contig4-2985_0023|orf6.5595|CA3354|CaO19.1944|CaO19.9499|CA3354 gi:30513635|IPF11281 Putative G-protein-coupled receptor of plasma membrane; required for wild-type hyphal growth; acts in cAMP-PKA pathway; reports differ on role in cAMP-mediated glucose signaling; Gpr1p C terminus binds Gpa2p; regulates HWP1 and ECE1 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 283868 286240 + orf19.1943 283868 286240 1 283868 286240 283868 286240 orf19.9498|IPF11277.2|IPF29244.1|Contig4-2985_0019|Contig4-2985_0020|orf6.5596|CA3355|CaO19.1943|IPF11277 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 286704 288826 + orf19.1942 286704 288826 1 286704 288826 286755 288638 SGE1 orf19.9497|orf6.5597|IPF9560.2|IPF29247.1|Contig4-2985_0017|CA3356|SGE12|CaO19.1942|CaO19.9497|IPF9560 Protein described as a multidrug resistance factor; transcriptionally regulated by iron; expression greater in low iron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 288651 290203 - orf19.1941 288651 290203 1 290203 288651 290177 288720 NUF2 orf19.9496|IPF25366.1|IPF9562.2|Contig4-2985_0015|orf6.5598|CA3357|CaO19.9496|CaO19.1941|IPF9562 Kinetochore component; amount of Nuf2p and Mtw1p protein detected at each centromere is consistent with a single kinetochore microtubule attachment site [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr5 290353 291315 - orf19.1940 290353 291315 1 291315 290353 291183 290443 orf19.9495|IPF25378.1|IPF19984.1|Contig4-2985_0013|orf6.5599|CA3358|CAT5|CaO19.1940|CaO19.9495|IPF19984 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 291412 292591 + ntar_870 291412 292591 1 291412 292591 291706 291870 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 291435 292571 - orf19.1939 291435 292571 1 292571 291435 292571 291477 orf19.9494|IPF25374.1|IPF9566.2|Contig4-2985_0012|orf6.5600|CA3359|CaO19.9494|CaO19.1939|IPF9566 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr5 292842 292987 + ntar_871 292842 292987 1 292842 292987 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 293624 294470 + orf19.1938 293624 294470 1 293624 294470 293764 294402 orf19.9493|IPF9568.1|IPF9569.2|IPF9568|Contig4-2985_0006|orf6.5601|CA3360|CaO19.1938 Decreased transcription is observed in an azole-resistant strain that overexpresses CDR1 and CDR2; increased transcription is observed upon benomyl treatment [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 294617 296595 + orf19.1936 294617 296595 1 294617 296595 294667 296523 SNF1 orf19.9491|IPF9571.2|IPF19131.2|Contig4-2985_0003|orf6.5603|orf6.832|CA3361|CaO19.1936 Essential protein; functional homolog of S. cerevisiae Snf1p regulator of sugar metabolism; constitutively expressed; Thr208 phosphorylation may have regulatory role; up-regulation associated with azole resistance; has polyhistidine tract [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 296722 297421 + orf19.1935 296722 297421 1 296722 297421 296722 297168 IPF9572.1|Contig4-2985_0002|orf6.831|CaO19.1935 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 297424 299231 + orf19.1934 297424 299231 1 297424 299231 297649 299112 orf19.9490|IPF25371.1|IPF9787.2|Contig4-2583_0018|Contig4-2985_0001|orf6.5604|orf6.830|CA0197|HST3|CaO19.1934|IPF9787 Predicted ORF in Assemblies 19, 20 and 21; repressed upon high-level peroxide stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 299390 301978 + orf19.1933 299390 301978 1 299390 301978 299586 301436 orf19.9489|IPF9789.2|IPF19133.2|Contig4-2583_0014|Contig4-2583_0017|orf6.5605|orf6.829|CA3362|CaO19.1933|IPF9789 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 303290 305640 + orf19.1932 303290 305640 1 303290 305640 303390 305522 CFL4 orf19.9488|orf6.292|FRE5|FRE32|IPF9791.2|IPF19355.2|CFL94|Contig4-2583_0010|orf6.5606|CA3363|CaO19.1932 Similar to ferric reductase, C-terminal region; expression greater in low iron; transcription is negatively regulated by Sfu1p; ciclopirox olamine induced; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 308765 310897 + orf19.1930 308765 310897 1 308765 310897 308765 310897 CFL5 orf19.9486|orf6.5607|orf6.1281|FRE31|IPF25358.1|IPF15107.3|FRE4|CFL90|Contig4-2699_0003|Contig4-2699_0004|CA0397|CaO19.1930|IPF15107.2 Protein similar to ferric reductase Fre10p; expression greater in low iron; negatively regulated by Sfu1p; ciclopirox olamine, flucytosine induced; amphotericin B repressed; transcription is positively regulated by Tbf1p [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 310852 311867 - orf19.1927 310852 311867 1 311867 310852 311744 311136 SNM1 orf19.9483|IPF19001.2|IPF15109.2|Contig4-2699_0002|orf6.1278|CA0396|CaO19.1927|CaO19.9483 Protein described as similar to RNase MRP RNA binding protein; ciclopirox olamine induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 313139 315341 + orf19.1926 313139 315341 1 313139 315341 313350 315341 SEF2 orf19.9482|orf19.11606|IPF25372.1|IPF15112.2|IPF23122.1|IPF18736.1|Contig4-2911_0020|orf6.1277|orf6.2618|CA0395|orf19.4129|CaO19.9482|CaO19.1926|SEF11.5eoc Putative zinc cluster protein; expression is repressed by Sfu1p under high-iron conditions [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=H scenario_last_exon=H] Ca21chr5 315207 318050 - orf19.4131 315207 318050 1 318050 315207 317987 315402 orf19.11608|IPF23115.1|IPF14870.2|Contig4-2911_0018|Contig4-2911_0019|orf6.2616|CA1223|CaO19.4131|CaO19.11608|IPF14870 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 318216 319156 + orf19.4132 318216 319156 2 318216|318479 318410|319156 318368 318687 orf19.11609|IPF23123.1|IPF14871.1|Contig4-2911_0016|orf6.2615|CA1222|CaO19.11609|CaO19.4132|SNA2|IPF14871 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 319296 319618 + ntar_872 319296 319618 1 319296 319618 319456 319590 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 319309 320913 - orf19.4133 319309 320913 1 320913 319309 320892 319510 orf19.11610|IPF23119.1|IPF14872.2|Contig4-2911_0014|orf6.2614|CA1221|CaO19.4133|CaO19.11610|IPF14872 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 320959 322541 - orf19.4134 320959 322541 1 322541 320959 322260 321043 orf19.11611|IPF23120.1|IPF14985.2|Contig4-2911_0013|orf6.2613|CA1220|CaO19.11611|CaO19.4134|IPF14985 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 322654 324329 + orf19.4135 322654 324329 1 322654 324329 322744 324240 PRC2 orf19.11612|IPF9814.2|IPF14986.2|Contig4-2911_0012|orf6.2612|orf6.5243|CA1219|CPY3|CaO19.4135 Protein described as a carboxypeptidase; upregulated in the presence of human neutrophils [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 324409 328268 + orf19.4136 324409 328268 1 324409 328268 324438 328229 YBL053 orf19.11613|IPF9818.2|IPF14987.3|Contig4-2911_0009|Contig4-2911_0010|orf6.2611|orf6.5242|orf6.5240|CA3093|CA6319|orf19.4138|orf19.4139|TOF1|TOF1.5f Predicted ORF in Assemblies 19, 20 and 21; not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 328167 329870 - orf19.4142 328167 329870 1 329870 328167 329793 328285 orf19.11617|orf19.11618|IPF9821.2|IPF19600.1|IPF19601.2|IPF9821.5f|Contig4-2911_0007|Contig4-2911_0008|orf6.5238|orf6.5237|orf6.717|CA3092|CA3091|orf19.4141 Predicted ORF in Assemblies 19, 20 and 21; decreased transcription is observed upon fluphenazine treatment [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 330456 330997 + orf19.4143 330456 330997 1 330456 330997 330482 330910 orf19.11619|IPF18385.1|IPF9823.2|Contig4-2911_0006|orf6.5236|orf6.718|CA3090|CaO19.4143|IPF18385 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 330905 332874 - orf19.4144 330905 332874 1 332874 330905 332823 331012 orf19.11620|IPF9825.2|IPF19173.1|Contig4-2911_0005|orf6.5235|orf6.719|CA3089|CaO19.4144|IPF9825 Predicted ORF in Assemblies 19, 20 and 21; clade-associated gene expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 333089 336568 - orf19.4145 333089 336568 1 336568 333089 336412 333155 ZCF20 orf19.11621|IPF9826.2|IPF19172.2|Contig4-2294_0005|Contig4-2911_0001|orf6.236|orf6.5234|orf6.720|CA3088|CaO19.4145|IPF9826 Predicted zinc-finger protein of unknown function [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr5 336922 337187 - ntar_873 336922 337187 1 337187 336922 337171 337025 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 338168 338860 + orf19.4146 338168 338860 1 338168 338860 338300 338620 SMD3 orf19.11622|IPF14903.1|IPF19380.1|Contig4-2294_0001|orf6.235|orf6.5233|CA3087|CaO19.4146 Protein described as a core snRNP protein; induced upon adherence to polystyrene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 338662 340461 - orf19.4147 338662 340461 1 340461 338662 340319 338769 GLR1 orf19.11623|IPF14902.2|IPF28513.1|Contig4-2850_0001|orf6.234|orf6.5232|CA3086|CaO19.4147 Glutathione reductase; transcriptionally regulated by Cap1p; upregulated in the presence of human neutrophils; oxidative stress-induced via Cap1p; overexpression correlates with multidrug resistance in a cap1 mutant, farnesol induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 340697 342392 - orf19.4148 340697 342392 1 342392 340697 342233 340785 orf19.11624|IPF11622.3|IPF17086.2|Contig4-2850_0004|orf6.5231|CA3085|CaO19.4148|CaO19.11624|IPF17086 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 342742 344165 + orf19.4149.1 342742 344165 2 342742|343344 342960|344165 342916 343766 IPF23127.1|IPF20127.1 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 343416 343904 - orf19.4149 343416 343904 1 343904 343416 343904 343416 orf19.11625|IPF23121.1|IPF11625.2|Contig4-2850_0005|Contig4-2850_0007|orf6.5230|CA3084|CaO19.4149|CaO19.11625|IPF11625 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 343961 344954 - orf19.4150 343961 344954 1 344954 343961 344807 344118 orf19.11626|IPF11626.2|IPF16833.3|Contig4-2850_0008|orf6.5229|orf6.554|CA3083|CaO19.4150|CaO19.11626|IPF11262 Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 345240 347570 - orf19.4151 345240 347570 2 347570|347282 347379|345240 347570 345240 SPO1 orf19.11628|IPF23116.1|IPF16830.2|Contig4-2850_0013|orf6.5227|orf6.553|CA0111|CaO19.4151|IPF16830 Protein similar to phospholipase B; fungal-specific (no human or murine homolog) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 345260 345403 + ntar_874 345260 345403 1 345260 345403 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 345945 346138 + ntar_875 345945 346138 1 345945 346138 345974 346138 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 347709 351099 - orf19.4152 347709 351099 1 351099 347709 351071 347919 CEF3 orf19.11629|TEF3|YEF3|EFT3|IPF11638.2|IPF16826.3|HEF1|Contig4-2850_0015|orf6.5226|orf6.552|CA3081|CaO19.4152 Translation elongation factor 3 (EF-3); antigenic in human; predicted C-term nucleotide-binding active site, poly-Lys region; PROTEIN localizes to surface of yeast form, not hyphae; polystyrene adherence induced; EF-3 is fungal-specific [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 351313 351752 + ntar_876 351313 351752 1 351313 351752 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 352009 352396 + ntar_877 352009 352396 1 352009 352396 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 352409 352696 - ntar_878 352409 352696 1 352696 352409 352543 352409 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 353182 355057 + orf19.4153 353182 355057 1 353182 355057 353433 355034 orf19.13678|orf19.11630|IPF23118.1|IPF14634.2|IPF20861.1|IPF18364.2|Contig4-2850_0022|orf6.5225|orf6.5449|CA3080|orf19.6299|ULA1|CaO19.4153|CaO19.11630|IPF14634 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr5 354823 357167 - orf19.6298 354823 357167 1 357167 354823 357106 355211 SPB4 orf19.13677|orf19.11631|IPF23117.1|IPF14636.2|IPF20846.1|IPF15694.1|Contig4-2128_0004|orf6.5224|orf6.5448|CA3237|orf19.4154|CaO19.6298|SPB41|CaO19.13677 Predicted ORF in Assemblies 19, 20 and 21; flucytosine repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 357170 358850 + orf19.6297 357170 358850 1 357170 358850 357170 358639 orf19.13676|IPF20852.1|IPF15695.1|Contig4-2128_0002|orf6.5447|CA3236|DEG1|CaO19.6297|CaO19.13676 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr5 358590 359496 - orf19.6296 358590 359496 1 359496 358590 359455 358670 orf19.13675|IPF20856.1|IPF15696.2|Contig4-2128_0001|orf6.5446|CA3235|CaO19.13675|SNF8|CaO19.6296 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 360957 362706 + orf19.6295 360957 362706 1 360957 362706 360974 362542 MAS2 orf19.13674|IPF20850.1|IPF10850.2|Contig4-2045_0001|orf6.5445|CA3234|CaO19.13674|CaO19.6295 Predicted ORF in Assemblies 19, 20 and 21; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 362550 368622 - orf19.6294 362550 368622 1 368622 362550 368537 362691 MYO1 orf19.13673|IPF20864.1|IPF10851.2|Contig4-2045_0002|orf6.5444|CA3233|CaO19.6294|CaO19.13673 Component of actomyosin ring at neck of newly-emerged bud [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr5 369123 369595 + ntar_879 369123 369595 1 369123 369595 369253 369390 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 375493 377133 + orf19.3208 375493 377133 1 375493 377133 375493 377133 DAL52 orf19.10720|IPF24124.1|IPF14177.2|Contig4-2538_0004|Contig4-2538_0005|orf6.1025|orf6.4391|DAL6|CA2478|CaO19.10720|DAL54|CaO19.3208 Putative allantoate permease; fungal-specific (no human or murine homolog); not essential for viability; similar to S. cerevisiae Dal5p [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 377136 380007 - orf19.3207 377136 380007 1 380007 377136 379759 377678 CCN1 orf19.10719|CLN1|IPF24117.1|IPF15597.2|Contig4-2538_0006|orf6.4392|CA2479|CaO19.10719|CaO19.3207 G1 cyclin; required for hyphal growth maintenance (not initiation); cell-cycle regulated transcription (G1/S); Cdc28p-Ccn1p initiates Cdc11p S394 phosphorylation on hyphal induction; expression in S. cerevisiae inhibits pheromone response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 382385 384224 - orf19.3206 382385 384224 1 384224 382385 384157 382508 CCT7 orf19.10718|IPF9837.2|IPF28858.1|Contig4-2661_0012|orf6.158|orf6.4393|CA2480|CaO19.3206|CaO19.10718 Predicted ORF in Assemblies 19, 20 and 21. Protein detected by mass spec in exponential and stationary phase cultures. [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 384382 385244 + orf19.3205 384382 385244 1 384382 385244 384458 385090 orf19.10717|IPF24128.1|IPF9838.2|Contig4-2661_0011|orf6.4394|CA2481|CaO19.3205|MRPL36|CaO19.10717 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 385175 387592 - orf19.3204 385175 387592 1 387592 385175 387527 385311 orf19.10716|IPF24114.1|IPF9841.1|Contig4-2661_0010|orf6.4395|CA2482|CaO19.10716|CaO19.3204|IPF9841 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr5 387657 390564 - orf19.3203 387657 390564 1 390564 387657 390336 387781 RCY1 orf19.10715|IPF24110.1|IPF19758.1|Contig4-2661_0007|Contig4-2661_0008|orf6.4396|CA2483|CaO19.10715|CaO19.3203|IPF19758 Putative F-box protein involved in endocytic membrane traffic and/or recycling; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr5 387713 388108 + ntar_880 387713 388108 1 387713 388108 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 390658 393378 + orf19.3202 390658 393378 1 390658 393378 390739 393300 orf19.10714|IPF9846|IPF9846.2|IPF28851.1|Contig4-2661_0004|Contig4-2661_0006|orf6.4397|CA2484|CaO19.3202 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr5 393174 394502 - orf19.3201 393174 394502 3 394502|394222|393594 394297|393851|393174 394488 393526 MTLA1 A1|IPF11162.1|IPF11161.2|Contig4-2559_0015|orf6.1884|CA0760|IPF11161.3 A1p and Alpha2p act together to repress white-opaque switching and mating (an opaque-specific process); homeodomain protein; gene of the MTLa (Mating Type Like) locus; a/alpha mating type may increase virulence, competitive advantage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 394537 395279 - orf19.3200 394537 395279 2 395279|394928 394984|394537 395253 394593 MTLA2 A2|IPF11164.1|orf6.1883 Master regulator (activator) of a-type mating; has HMG domain, which is predicted to bind DNA; gene has intron; not related to S. cerevisiae MATa2; a/alpha mating type may increase virulence, provides competitive advantage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 395318 398266 - orf19.3199 395318 398266 1 398266 395318 398238 395368 PIKA IPF9853.1|IPF11166.2|Contig4-1611_0004|Contig4-2559_0011|Contig4-2559_0013|orf6.1882|CA6207|PIK1|CaO19.3199 Putative phosphatidylinositol kinase; gene is located within the MTLa mating-type-like locus [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 398731 400129 - orf19.3198 398731 400129 1 400129 398731 400104 398803 OBPA IPF9854.2|IPF11167.1|Contig4-1502_0001|Contig4-1611_0001|Contig4-2559_0010|orf6.1881|CA0759|CaO19.3198|OBPa|IPF11167 Similar to oxysterol binding protein; gene is located within the MTLa mating-type-like locus; Plc1p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 400487 402385 + orf19.3197 400487 402385 1 400487 402385 400510 402177 PAP1 IPF9850.1|IPF19882.1|Contig4-2559_0008|Contig4-2559_0009|orf6.1880|PAPa|CA0758|CaO19.3197|PAP11 Poly(A) polymerase, likely involved in mRNA polyadenylation; PAP is inhibited by parnafungin antifungals; gene is located within the MTLa mating-type-like locus [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 402485 402787 - orf19.3196 402485 402787 1 402787 402485 402787 402485 IPF24136.1|IPF28871.1|orf6.1879|CaO19.3196 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 402835 404785 - orf19.3195 402835 404785 1 404785 402835 404634 402835 HIP1 orf19.10706|IPF11171.3|IPF28855.1|GAP3|GAP7|Contig4-2559_0006|orf6.1878|orf6.4405|orf6.713|orf6.908|CA0160|CaO19.3195|GAP21|CA0757|GAP7.3eoc|IPF11170.2|GAP7.5eoc|IPF11171.2 Alkaline upregulated; flucytosine induced; regulated by Plc1p, Gcn2p and Gcn4p; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 407397 409610 + orf19.3193 407397 409610 1 407397 409610 407977 409176 FCR3 orf19.10704|orf6.906|IPF19842.1|IPF19852.1|Contig4-2798_0003|orf6.715|orf6.716|CA0219|YAP3|CaO19.3193 Transcriptional regulator of the bZip family; partially functionally complements the fluconazole sensitivity of an S. cerevisiae pdr1 pdr3 double mutant; probable ortholog of S. cerevisiae Yap3p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 409876 411922 + orf19.3192 409876 411922 1 409876 411922 409958 411727 STI1 orf19.10702|orf6.1022|IPF9198.3|IPF19105.2|Contig4-1933_0004|orf6.4488|orf6.905|CA0265|CA6273|orf19.3191|STI1.5f Protein that interacts with Cdc37p and Crk1p in two-hybrid system; may be involved in Cdc37p chaperone activity; biofilm induced; soluble protein in hyphae; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 411761 415413 - orf19.3190 411761 415413 1 415413 411761 415006 411971 HAL9 orf19.10701|ZNC3|IPF9196.1|IPF16067.2|Contig4-1956_0001|Contig4-1956_0002|orf6.4487|CA2542|CaO19.3190|HAL93|IPF16067 Protein with Zn(2)-Cys(6) binuclear cluster; gene in zinc cluster region of Chr. 5; transcriptionally activated by Mnl1p in weak acid; similar to S. cerevisiae Hal9p, which is a putative transcription factor involved in salt tolerance [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr5 415584 416046 + ntar_881 415584 416046 1 415584 416046 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 416300 419551 - orf19.3188 416300 419551 1 419551 416300 419375 416430 TAC1 orf19.10700|orf19.10699|ZNC2|IPF19124.2|IPF9191.2|Contig4-2456_0006|orf6.1024|orf6.4485|orf6.854|orf6.4486|orf6.855|TAC1-1|TAC1-2|CA2541|orf19.3189|IPF9191.3f Transcriptional activator of drug-responsive genes including CDR1 and CDR2; has Zn(2)-Cys(6) binuclear cluster; binds DRE element; gene in zinc cluster region near MTL locus; resequencing indicates that TAC1 spans orf19.3188 and orf19.3189 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 420729 423979 - orf19.3187 420729 423979 1 423979 420729 423724 420956 ZNC1 orf19.10697|IPF17473.2|IPF9188.2|Contig4-2456_0001|orf6.4484|orf6.852|orf6.853|CA2539|CaO19.3187|HAL91|IPF9188 Putative transcription factor; has Zn(2)-Cys(6) binuclear cluster; predicted to bind DNA; regulated by Gcn2p and Gcn4p; gene is located in zinc cluster region of Chromosome 5, near the MTL locus [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 424411 424746 + orf19.3186 424411 424746 1 424411 424746 424411 424746 IPF28870.1|orf6.4483|CaO19.3186 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 424769 427176 + orf19.3185 424769 427176 1 424769 427176 424769 427117 orf19.10695|IPF24113.1|IPF15324.2|Contig4-2288_0004|orf6.4482|CA2538|NAT1|CaO19.3185 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 427085 428015 - orf19.3184 427085 428015 1 428015 427085 427872 427225 orf19.10694|IPF24126.1|IPF20108.1|Contig4-2288_0005|orf6.4481|CA2537|SFT22|CaO19.3184|CaO19.10694|SFT21|IPF20108 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 428033 429008 + orf19.3183 428033 429008 1 428033 429008 428137 428811 orf19.10693|IPF24127.1|IPF20107.1|Contig4-1727_0001|Contig4-2288_0006|orf6.4480|CA2536|CaO19.3183|CaO19.10693|IPF20107 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 428616 429194 - orf19.3181.1 428616 429194 1 429194 428616 429048 428884 IPF24116.1|IPF20106.1|CA2535|NCE11 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 429549 430620 + orf19.3182 429549 430620 1 429549 430620 429623 430150 GIS2 orf19.10692|orf6.4479|IPF24129.1|IPF12793.2|Contig4-1727_0004|CA2534|CaO19.10692|CaO19.3182|IPF12793 Transcriptionally regulated by iron; expression greater in high iron; transcription reduced upon yeast-hyphal switch; similar to proteins that bind nucleic acid [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 429604 430590 - ntar_882 429604 430590 1 430590 429604 430126 429785 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 430800 432329 - orf19.3180 430800 432329 1 432329 430800 432245 430863 orf19.10690|IPF24125.1|IPF12790.2|Contig4-1727_0007|Contig4-2248_0003|orf6.4477|CA2533|INP54|CaO19.3180|CaO19.10690|IPF12790 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr5 432414 434097 + orf19.3178 432414 434097 1 432414 434097 432444 433985 orf19.10688|IPF24121.1|IPF20105.1|Contig4-2248_0005|orf6.4475|CA2532|CaO19.3178|PRP9|CaO19.10688 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 434195 436623 + orf19.3177 434195 436623 1 434195 436623 434212 435981 orf19.10687|IPF24120.1|IPF12784.2|Contig4-2248_0008|orf6.4474|CA2531|CaO19.10687|CaO19.3177|RIB2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 435899 437678 - orf19.3176 435899 437678 1 437678 435899 437588 435999 RIM21 orf19.10686|IPF16822.2|IPF12782.2|Contig4-2507_0010|orf6.1484|orf6.4473|CA2530|CaO19.3176|IPF12782 Protein involved in the pH response pathway; required for activation of the transcription factor Rim101p and for alkaline pH-induced hyphal growth; may function as a sensor of alkaline pH [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 436810 437042 + ntar_883 436810 437042 1 436810 437042 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 437877 440090 - orf19.3175 437877 440090 1 440090 437877 440048 438165 orf19.10685|IPF16916.2|IPF16824.3|Contig4-2507_0007|Contig4-2507_0008|orf6.1483|orf6.4472|YOR256W|CA0510|CaO19.3175|ETF1 Predicted ORF in Assemblies 19, 20 and 21; alkaline downregulated; repressed by nitric oxide; virulence-group-correlated expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 440598 443802 - orf19.3174 440598 443802 1 443802 440598 443366 440832 CDC24 orf19.10684|IPF19624.1|IPF19625.1|Contig4-2507_0005|orf6.1241|orf6.1482|CA0509|CaO19.3174 GDP-GTP exchange factor for Cdc42p; phosphorylated; required for maintenance of hyphal growth; misexpression blocks hyphal growth and causes avirulence in a mouse model of systemic infection; antigenic during human oral infection [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 443705 444572 + ntar_884 443705 444572 1 443705 444572 444177 444446 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 444478 445572 - orf19.3173 444478 445572 1 445572 444478 445544 444864 orf19.10683|IPF19030.2|IPF12012.2|Contig4-1691_0006|orf6.1240|CA0379|SSP120|CaO19.3173 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 446231 446632 + orf19.3172 446231 446632 1 446231 446632 446231 446632 orf19.10682|IPF12010.2|IPF28867.1|Contig4-1566_0001|Contig4-1691_0001|orf6.1163|orf6.1239|CaO19.3172 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 446783 448830 - orf19.3171 446783 448830 1 448830 446783 448569 446995 ACH1 orf19.10681|IPF12009.2|IPF28861.1|Contig4-1566_0005|orf6.1164|orf6.1238|CA0345|CaO19.3171 Acetyl-coA hydrolase; acetate utilization; nonessential; soluble protein in hyphae; antigenic in human; induced on polystyrene adherence; farnesol-, ketoconazole-induced; no human or murine homolog [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 449688 449952 + ntar_885 449688 449952 1 449688 449952 449818 449952 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 451270 453611 - orf19.3170 451270 453611 1 453611 451270 453568 451382 orf19.10680|IPF18726.2|IPF3178.2|Contig4-2939_0001|orf6.1165|orf6.1234|orf6.2668|CA0378|CaO19.3170|IPF3178 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 453759 454987 - orf19.3169 453759 454987 1 454987 453759 454903 453845 orf19.10678|IPF18725.1|IPF3177.2|Contig4-2939_0002|orf6.1235|orf6.2669|CA1257|CaO19.3169|IPF18725 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 455173 456244 + orf19.3168 455173 456244 1 455173 456244 455238 456230 RPN8 orf19.10677|IPF18724.1|IPF3176.2|Contig4-2939_0004|orf6.1236|orf6.2670|CA1258|CaO19.3168 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to amphotericin B; transcription is regulated by Mig1p; regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 456395 457916 + orf19.3167 456395 457916 1 456395 457916 456472 457857 orf19.10676|IPF3174.2|IPF19016.2|Contig4-2939_0006|orf6.1237|orf6.2671|CA1259|COX10|CaO19.3167|IPF3174 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 458101 463296 + orf19.3166 458101 463296 1 458101 463296 458193 463202 orf19.10675|IPF24132.1|IPF3170.2|Contig4-2939_0010|orf6.2672|CA1260|DOP1|CaO19.3166|CaO19.10675|IPF3170 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 463390 464450 + orf19.3163 463390 464450 1 463390 464450 463418 464404 orf19.10672|IPF19637.2|IPF28863.1|Contig4-2939_0011|orf6.1665|orf6.2675|CA0625|CaO19.3163|IPF19637|IPF19638.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 464332 465544 - orf19.3161 464332 465544 1 465544 464332 465402 464440 orf19.10670|IPF17400.3|IPF3161.2|Contig4-2939_0012|orf6.1667|orf6.1772|CA0626|CaO19.3161|IPF3161 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 465537 465883 + ntar_886 465537 465883 1 465537 465883 465650 465796 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 466373 466879 - orf19.3160 466373 466879 1 466879 466373 466879 466373 HSP12 orf19.10669|orf19.13883|orf6.1668|IPF3160.2|CA0627|CaO19.3160 Heat-shock protein; induced upon osmotic/oxidative/cadmium stress, fluphenazine treatment, low iron, CDR1 and CDR2 overexpression, or ssn6 or ssk1 homozygous null mutation; repressed by Hog1p, flucytosine, elevated CO2 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 467497 467790 + orf19.3159.4 467497 467790 1 467497 467790 467497 467790 IPF3152.1|IPF28869.1|Contig4-2734_0009 ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 473411 473917 + orf19.4216 473411 473917 1 473411 473917 473411 473917 orf19.11692|HSP12|Contig4-2148_0004|Contig4-2734_0007|Contig4-2734_0006|IPF23008.1|IPF17399.2|orf6.1771|orf6.2761|CaO19.11692|CaO19.4216|CaO19.10669 Predicted ORF in Assemblies 19, 20 and 21; decreased expression in hyphae compared to yeast-form cells; transcription is increased in populations of cells exposed to fluconazole over multiple generations [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 473926 474113 + ntar_887 473926 474113 1 473926 474113 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 474209 476995 - orf19.4219 474209 476995 1 476995 474209 476853 474370 RIX7 orf19.11695|IPF22933.1|IPF3147.2|Contig4-2936_0001|orf6.2764|CA1318|YLL34|CaO19.4219|CaO19.11695|IPF3147 Protein similar to S. cerevisiae Rix7p which is a putative ATPase of the AAA family required for ribosomal subunit export from the nucleus; mutation impairs hyphal growth and biofilm formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 474794 475372 + orf19.4217 474794 475372 1 474794 475372 474794 475372 IPF22996.1|IPF3146.1|orf6.2762 [NOT TRANSCRIBED?] ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 477021 477828 - orf19.4220 477021 477828 1 477828 477021 477815 477264 orf19.11696|IPF23004.1|IPF3144.2|Contig4-2936_0002|orf6.2765|CA1319|CaO19.4220|CaO19.11696|IPF3144 Predicted ORF in Assemblies 19, 20 and 21; regulated by Gcn4p; repressed in response to amino acid starvation (3-aminotriazole treatment) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 477916 479905 - orf19.4221 477916 479905 1 479905 477916 479720 478026 ORC4 orf19.11697|IPF22966.1|IPF3143.2|Contig4-2936_0005|orf6.2766|CA1320|CaO19.11697|CaO19.4221|IPF3143 Phosphorylated protein similar to S. cerevisiae Orc4p; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 480271 482298 + orf19.4222 480271 482298 1 480271 482298 480271 482298 SST2 orf19.11698|IPF22951.1|IPF3141.2|Contig4-2936_0006|orf6.2767|CA1321|CaO19.4222|CaO19.11698|IPF3141 Predicted regulator of G-protein signaling in mating pathway; homozygous null mutation causes alpha-factor hypersensitivity and mating defect (in an opaque MTLa/MTLa background); transcription induced by alpha factor [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr5 482206 484016 - orf19.4223 482206 484016 1 484016 482206 483987 482383 GCD11 orf19.11699|EIF2|IPF18245.2|IPF3140.1|Contig4-2936_0007|orf6.2768|orf6.6621|CA1322|CaO19.11699|CaO19.4223 Protein similar to S. cerevisiae Gcd11p, which is a subunit of translation initiation factor eIF2; likely to be essential for growth, based on an insertional mutagenesis strategy [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 484154 487225 - orf19.4225 484154 487225 1 487225 484154 487140 484186 LEU3 orf19.11700|IPF3138.2|IPF17458.3|Contig4-2936_0008|Contig4-2936_0011|Contig4-2936_0012|orf6.484|orf6.6620|orf6.2769|CA4146|CaO19.4225 Predicted zinc-finger protein; has similarity to S. cerevisiae Leu3p, which is involved in regulation of branched-chain amino acid biosynthesis genes; alkaline upregulated; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 484182 484675 + ntar_888 484182 484675 1 484182 484675 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 487539 488260 - orf19.4225.1 487539 488260 2 488260|488051 488128|487539 488200 487831 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 488684 489778 + orf19.4227 488684 489778 1 488684 489778 488684 489778 orf19.11702|IPF22986.1|IPF3130.1|Contig4-2936_0016|orf6.6618|CA4145|CaO19.4227|CaO19.11702|IPF3130 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 488750 489835 - ntar_889 488750 489835 1 489835 488750 489249 489004 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 489805 491211 + orf19.4228 489805 491211 1 489805 491211 489979 490962 orf19.11703|IPF22990.1|IPF13340.2|Contig4-2936_0017|orf6.6617|CA4144|CaO19.4228|CaO19.11703|IPF13340 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 490999 491851 - orf19.4229 490999 491851 1 491851 490999 491689 491111 orf19.11704|IPF23003.1|IPF13339.2|Contig4-2936_0018|orf6.6616|CA4143|DDP1|CaO19.11704|CaO19.4229 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 492255 493255 + orf19.4230 492255 493255 1 492255 493255 492387 493232 orf19.11705|IPF13337.2|IPF19084.2|Contig4-2936_0020|orf6.6615|orf6.967|CA4142|PRE4|CaO19.4230 Predicted ORF in Assemblies 19, 20 and 21; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr5 498728 499921 + orf19.4231 498728 499921 1 498728 499921 498728 499921 PTH2 orf19.11706|IPF16485.2|IPF19085.2|Contig4-1833_0002|orf6.6614|orf6.966|CA6212|CaO19.11706|CaO19.4231|CA4141 Predicted ORF in Assemblies 19, 20 and 21; constitutive expression independent of MTL or white-opaque status [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr5 500335 500472 - ntar_890 500335 500472 1 500472 500335 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 501180 502937 - orf19.4232 501180 502937 1 502937 501180 502899 501490 PTH1 orf19.11707|IPF22975.1|IPF11959.2|Contig4-1677_0001|orf6.6613|CA4140|CaO19.11707|CaO19.4232|IPF11959 Putative gluconate transport protein; antigenic during human oral infection [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 503271 505092 + orf19.4233 503271 505092 1 503271 505092 503329 504861 THR4 orf19.11708|IPF22974.1|IPF11957.2|Contig4-2131_0002|orf6.6612|CA4139|CaO19.11708|CaO19.4233 Predicted ORF in Assemblies 19, 20 and 21; Gcn4p-regulated; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 504862 506353 - orf19.4234 504862 506353 1 506353 504862 506321 504930 orf19.11709|IPF22973.1|IPF11954.2|Contig4-2131_0003|orf6.6611|CA4138|CTR86|CaO19.4234|CaO19.11709|IPF11954 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 508074 509533 + orf19.4235 508074 509533 1 508074 509533 508165 509445 PDE1 orf19.11710|IPF22979.1|IPF7003.2|Contig4-2019_0002|orf6.6610|CA4137|CNA1|CaO19.11710|CaO19.4235 Cyclic nucleotide phosphodiesterase (PDEase), low affinity; has activity toward cGMP and cAMP; not divalent cation-dependent; complements defects of an S. cerevisiae mutant lacking PDEase; macrophage-downregulated gene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 509525 511482 - orf19.4236 509525 511482 1 511482 509525 511369 509648 RET2 orf19.11711|IPF22965.1|IPF7005.2|Contig4-2209_0001|orf6.6609|CA4136|CaO19.4236|CaO19.11711 Protein that interacts with Crk1p in the two-hybrid system; potential ortholog of S. cerevisiae Ret2p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 511629 513644 - orf19.4239 511629 513644 2 513644|511664 511749|511629 513644 511629 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 511659 512318 + ntar_891 511659 512318 1 511659 512318 511859 511999 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 512955 513774 + ntar_892 512955 513774 1 512955 513774 513643 513768 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 513888 515290 - orf19.4240 513888 515290 1 515290 513888 515226 514042 orf19.11715|IPF22985.1|IPF7009.2|Contig4-2209_0005|orf6.6605|CA4134|CaO19.11715|CaO19.4240|COS162 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 515350 516067 + orf19.4241 515350 516067 1 515350 516067 515686 516000 orf19.11716|IPF23019.1|IPF7011.1|Contig4-2769_0007|orf6.6604|CA4133|CaO19.11716|CaO19.4241|IPF7010|IPF7010.3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 515746 515941 - ntar_893 515746 515941 1 515941 515746 515941 515810 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 517649 522072 - orf19.4242 517649 522072 1 522072 517649 521587 517901 CST20 orf19.11717|STE20|IPF23033.1|IPF7017.1|Contig4-2769_0006|orf6.6603|CA4132|CaO19.11717|CaO19.4242 Protein kinase of Ste20p/p65PAK family, required for wild-type mating efficiency and virulence in a mouse model; Cst20p-Hst7p-Cek1p-Cph1p MAPK pathway regulates some hyphal growth; involved in Cdc42p growth regulation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 522717 522887 + ntar_894 522717 522887 1 522717 522887 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 522812 522955 - ntar_895 522812 522955 1 522955 522812 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 523337 523567 + ntar_896 523337 523567 1 523337 523567 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 523542 524735 - orf19.4243 523542 524735 1 524735 523542 524535 523657 orf19.11718|IPF6886.2|IPF7018.3|Contig4-2769_0009|orf6.3981|orf6.6602|YKL090|CA4131|CaO19.4243|IPF6886.3f|IPF6886 Predicted ORF in Assemblies 19, 20 and 21; not essential for viability; similar to S. cerevisiae Cue2p, which is a protein containing two CUE domains that bind ubiquitin [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 524847 525401 - orf19.4244 524847 525401 1 525401 524847 525349 524873 orf19.11719|IPF18247.1|IPF18521.1|orf6.3980|orf6.6601|YIL130|CA6213|CaO19.4244|IPF6886.5f Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 525630 527129 - orf19.4245 525630 527129 1 527129 525630 527057 525711 orf19.11720|IPF20009.1|IPF19942.1|Contig4-1884_0003|Contig4-1884_0004|orf6.3979|orf6.6600|CA4130|CaO19.4245|IPF20009 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 529534 531624 + orf19.4246 529534 531624 1 529534 531624 529708 531501 orf19.11721|IPF22957.1|IPF6881.2|Contig4-2928_0003|orf6.3978|orf6.6599|YKR070W|CA2186|CaO19.4246|IPF6881 Predicted ORF in Assemblies 19, 20 and 21; similar to S. cerevisiae Ykr070wp; transposon mutation affects filamentous growth; Hog1p-downregulated; shows colony morphology-related gene regulation by Ssn6p; induced during cell wall regeneration [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 531581 532923 - orf19.4247 531581 532923 1 532923 531581 532696 531752 orf19.11722|IPF22991.1|IPF6880.2|Contig4-2928_0005|orf6.3977|orf6.6598|CA2185|CaO19.4247|IPF6880 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 533084 534226 + orf19.4248 533084 534226 1 533084 534226 533248 534153 orf19.11723|IPF6878.1|IPF17590.2|Contig4-1624_0001|Contig4-2928_0007|orf6.3976|orf6.6597|CA4129|CaO19.4248|IPF6878 Predicted ORF in Assemblies 19, 20 and 21; regulated by Gcn4p; repressed in response to amino acid starvation (3-aminotriazole treatment) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 534168 534805 - orf19.4250 534168 534805 1 534805 534168 534751 534227 orf19.11725|IPF6876.1|IPF17588.1|Contig4-1624_0004|Contig4-2928_0009|orf6.3974|orf6.6595|CA4128|CaO19.4250|IPF6876 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 535344 537678 + orf19.4251 535344 537678 1 535344 537678 535579 537678 ZCF22|orf19.11726|IPF22947.1|IPF6874.2|Contig4-2928_0011|orf6.3973|orf6.6594|CA2184|CaO19.4251|IPF6874.3f|IPF6874.3 Predicted zinc-finger protein of unknown function [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chr5 537613 538663 - orf19.4252 537613 538663 1 538663 537613 538630 537740 orf19.11727|IPF22993.1|IPF6872.1|Contig4-2928_0012|orf6.3972|CA2183|CaO19.4252|CaO19.11727|IPF6872 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 538764 541400 + orf19.4253 538764 541400 1 538764 541400 538910 541255 orf19.11728|IPF22943.1|IPF6871.1|Contig4-2928_0013|Contig4-2928_0014|orf6.3971|CA2182|CaO19.11728|CaO19.4253|IPF6871 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 541344 543083 - orf19.4255 541344 543083 1 543083 541344 542775 541534 ECM331 orf19.11730|orf6.3969|PST1|ECM33|IPF22981.1|IPF6869.2|Contig4-2928_0015|CA2181|CaO19.11730|CaO19.4255 GPI-anchored protein; mainly at plasma membrane, also at cell wall; caspofungin induced; Plc1p-regulated; repressed by Rim101p, Hog1p; colony morphology-related gene regulation by Ssn6p; induced in cyr1 homozygous null mutant yeast-form cel [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 547586 553401 + orf19.4257 547586 553401 2 547586|548236 547800|553401 547677 553247 INT1 orf19.11733|BUD4|orf6.3968|IPF19580.2|IPF28466.1|Contig4-2319_0007|orf6.1732|orf6.358|CA0665|CaO19.4257|IPF19580.1 Integrin-like protein; role in morphogenesis, adhesion, and mouse cecal colonization and systemic virulence; similar to S. cerevisiae Bud4p (has role in bud site selection); structurally similar to alpha-subunit of human leukocyte integrins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 553732 555164 + orf19.4258 553732 555164 1 553732 555164 553778 554758 orf19.11734|IPF18911.1|IPF16890.3|Contig4-2595_0003|orf6.1733|orf6.357|CA0666|FIP1|CaO19.4258 Putative protein of unknown function; heterozygous null mutant exhibits hypersensitivity to parnafungin and cordycepin in the C. albicans fitness test; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 554977 556653 - orf19.4261 554977 556653 1 556653 554977 556500 555238 TIF5 orf19.11737|IPF15194.3|IPF28461.1|orf6.1736|CA0667|CaO19.4261|CaO19.11737|IPF15194.2 Putative translation initiation factor; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 556783 557085 + ntar_897 556783 557085 1 556783 557085 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 556951 557308 - ntar_898 556951 557308 1 557308 556951 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 557443 559089 - orf19.4262 557443 559089 1 559089 557443 559089 557647 orf19.11738|IPF22967.1|IPF15191.2|Contig4-2758_0008|orf6.1031|CA0268|JSN1|CaO19.4262|CaO19.11738|PUF2.3f|PUF2.exon2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 559336 560826 - orf19.4263 559336 560826 1 560826 559336 560499 559336 orf19.11739|IPF22980.1|IPF15189.2|orf6.1032|CA0269|CaO19.4263|CaO19.11739|PUF2.5f|PUF2.exon1 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 562077 562600 + ntar_899 562077 562600 1 562077 562600 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 562815 564109 + orf19.4264 562815 564109 1 562815 564109 562920 563825 orf19.11740|IPF9520.1|IPF19069.2|Contig4-2550_0015|orf6.1033|orf6.3493|CA1827|CaO19.11740|CaO19.4264|IPF9520 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 564208 564790 - ntar_900 564208 564790 1 564790 564208 564722 564483 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 564942 566710 + orf19.4265 564942 566710 1 564942 566710 565078 566538 UAP1 orf19.11741|YDL103|IPF22969.1|IPF9521.2|Contig4-2550_0010|orf6.3492|CA1826|QRI1|CaO19.11741|CaO19.4265 UDP-N-acetylglucosamine pyrophosphorylase, catalyzes biosynthesis of UDP-N-acetylglucosamine from UTP and N-acetylglucosamine 1-phosphate; functional homolog of S. cerevisiae Qri1p; alkaline upregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 566565 568047 - orf19.4266 566565 568047 3 568047|567494|567201 567615|567275|566565 568047 566673 SPR28 orf19.11742|orf19.11743|IPF23010.1|IPF22929.1|IPF23006.1|IPF9524.1|IPF9523.1|IPF9522.1|Contig4-2550_0005|Contig4-2550_0008|Contig4-2550_0009|orf6.3491|orf6.3490|CA1823|orf19.4267|CA1824|IPF9522.53f Septin; similar to S. cerevisiae meiotic/sporulation septin; mutant has no obvious phenotype; two introns with noncanonical branch site and 5' splice site, respectively; splicing inhibited upon exposure to alpha-factor [label_first_exon=CGD label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=I] Ca21chr5 568110 570509 - orf19.4268 568110 570509 1 570509 568110 570509 568110 UTP13 orf19.11744|IPF22940.1|IPF9525.2|Contig4-2550_0003|orf6.3489|CA1822|CaO19.4268|CaO19.11744|IPF9525 Predicted ORF in Assemblies 19, 20 and 21; downregulated in core stress response; physically interacts with TAP-tagged Nop1p [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 570718 572572 - orf19.4269 570718 572572 1 572572 570718 572472 570718 orf19.11745|IPF22964.1|IPF9527.2|Contig4-2550_0001|orf6.3488|CA1821|CaO19.11745|CaO19.4269|IPF9527 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 573069 575543 + orf19.4270 573069 575543 1 573069 575543 573196 575493 orf19.11746|IPF22942.1|IPF9529.2|orf6.3487|CA1820|CaO19.11746|CaO19.4270|IPF9529 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr5 575778 576656 + orf19.4271 575778 576656 1 575778 576656 575995 576300 orf19.11747|orf6.3486|CaO19.11747|CaO19.4271 Predicted ORF from Assembly 19; removed from Assembly 20; subsequently reinstated in Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 576446 579407 - orf19.4273 576446 579407 1 579407 576446 579346 576587 orf19.11749|IPF22931.1|IPF16549.2|Contig4-2872_0001|orf6.3484|CA1819|CaO19.11749|CaO19.4273|IPF16549 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr5 580957 582618 + orf19.4274 580957 582618 1 580957 582618 580957 582426 PUT1 orf19.11750|IPF22968.1|IPF8739.2|Contig4-2872_0006|orf6.3112|orf6.3483|CA1552|CaO19.4274|IPF8739.1 Alkaline upregulated by Rim101p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr5 582504 586237 - orf19.4275 582504 586237 1 586237 582504 586193 582669 RAD9 orf19.11751|orf19.11752|IPF22941.1|IPF22987.1|IPF8741.1|IPF8742.1|Contig4-2872_0008|orf6.3111|orf6.3110|CA1551|CA1550|orf19.4276|IPF8741.3f Protein involved in regulation of DNA-damage-induced filamentous growth; putative component of DNA damage checkpoint; ortholog of S. cerevisiae Rad9p; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr5 586564 589123 - orf19.4278 586564 589123 1 589123 586564 588725 586716 orf19.11754|IPF22952.1|IPF8744.2|Contig4-2872_0009|orf6.3108|CA1549|CaO19.11754|CaO19.4278|IPF8744 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 589276 591903 - orf19.4279 589276 591903 1 591903 589276 591842 589440 MNN1 orf19.11755|orf6.3107|IPF17287.3|IPF8746.2|Contig4-2872_0014|orf6.5207|CA1548|CaO19.4279|IPF8746 Putative alpha-1,3-mannosyltransferase, a component of mannosyltransferase complex; transcription is negatively regulated by Rim101p; transcription is elevated in chk1 and nik1 homozygous null mutants, but not in the sln1 null mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 594388 595405 + orf19.4280 594388 595405 1 594388 595405 594542 595192 orf19.11756|IPF15811.2|IPF8750.2|Contig4-2551_0013|orf6.3106|orf6.5206|CA3067|CaO19.4280|IPF15811 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 595206 597036 - orf19.4281 595206 597036 1 597036 595206 596396 595503 orf19.11757|IPF22972.1|IPF15813.2|Contig4-2551_0010|orf6.5205|CA3066|CaO19.4281|CaO19.11757|IPF15813 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 597105 598196 - orf19.4282 597105 598196 1 598196 597105 598160 597123 orf19.11758|IPF19775.1|IPF19820.2|Contig4-2551_0007|orf6.5204|orf6.55|CA3065|CaO19.4282|IPF19775 Predicted ORF in Assemblies 19, 20 and 21; greater mRNA abundance observed in a cyr1 homozygous null mutant than in wild type; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 598231 598913 - ntar_901 598231 598913 1 598913 598231 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 599450 600170 - ntar_902 599450 600170 1 600170 599450 599844 599662 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 600619 601940 - orf19.4283 600619 601940 1 601940 600619 601853 600846 orf19.11759|IPF22989.1|IPF2973.2|Contig4-2551_0002|orf6.5203|CA3064|CaO19.11759|CaO19.4283|IPF2973 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 602692 604474 + orf19.4284 602692 604474 1 602692 604474 602769 604349 BUR2 orf19.11760|IPF2971|IPF22971.1|IPF2971.2|Contig4-3019_0001|orf6.5202|CA3063|SPX63|CaO19.4284|CaO19.11760 Protein with similarity to S. cerevisiae Bur2p, contains a cyclin domain; not required for wild-type hyphal growth, adherence to buccal epithelial cells, or virulence in mouse systemic infection [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 604631 605857 + orf19.4286 604631 605857 1 604631 605857 604784 605758 orf19.11762|IPF2968.1|IPF28462.1|Contig4-3019_0004|orf6.5200|CA3062|CaO19.4286|IPF2968 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 605938 607427 + orf19.4287 605938 607427 1 605938 607427 606065 607180 orf19.11763|IPF2965.2|IPF17863.2|Contig4-3019_0006|Contig4-3019_0008|orf6.172|orf6.5199|CA3061|BZD99|CaO19.4287|IPF2965 Predicted ORF in Assemblies 19, 20 and 21; clade-associated gene expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr5 607200 607583 - ntar_903 607200 607583 1 607583 607200 607583 607383 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 607530 610522 + orf19.4288 607530 610522 1 607530 610522 607672 610344 CTA7 orf19.11764|IPF2963.1|IPF28450.1|Contig4-3019_0010|orf6.5198|CA3060|STB4|CaO19.4288|CaO19.11764 Predicted zinc-finger protein of unknown function; activates transcription in 1-hybrid assay in S. cerevisiae; has similarity to S. cerevisiae Stb4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr5 611238 612455 + orf19.4290 611238 612455 1 611238 612455 611366 612328 TRR1 orf19.11766|IPF2959.2|IPF28463.1|Contig4-3019_0014|orf6.5196|CA3059|CaO19.4290|CaO19.11766 Putative thioredoxin reductase; upregulated in presence of human neutrophils; regulated by Tsa1p, Tsa1Bp; induced by nitric oxide; peroxide-induced; oxidative stress-induced via Cap1p; fungal-specific (no human/murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 612604 613610 + orf19.4292 612604 613610 1 612604 613610 612695 613525 orf19.11768|IPF22995.1|IPF2955.2|Contig4-3019_0016|orf6.5194|CA3058|CaO19.4292|CaO19.11768|IPF2955 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 613573 614794 - orf19.4293 613573 614794 1 614794 613573 614761 613610 orf19.11769|IPF22984.1|IPF2954.2|Contig4-3019_0017|Contig4-3019_0020|orf6.5193|CA3057|CaO19.4293|CaO19.11769|IPF2954 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 614929 616662 + orf19.4294 614929 616662 1 614929 616662 614957 616624 orf19.11770|IPF22959.1|IPF2953.2|Contig4-3019_0021|orf6.5192|CA3056|CaO19.4294|CYC2|CaO19.11770|IPF2953 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 616498 619795 - orf19.4295 616498 619795 1 619795 616498 619739 616686 orf19.11771|IPF2951.2|IPF28446.1|Contig4-3019_0023|orf6.5191|CA3055|CaO19.4295|HIR2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 620098 621363 + orf19.4297 620098 621363 1 620098 621363 620248 621051 CKB2 orf19.11773|CKB22|IPF18389.2|IPF2946.2|Contig4-3019_0024|orf6.4602|orf6.5189|CA2635|CaO19.4297|CaO19.11773 Regulatory subunit of protein kinase CK2 (casein kinase II), beta' subunit [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 621387 622740 + orf19.4299 621387 622740 1 621387 622740 621387 622586 MSW1 orf19.11775|IPF22983.1|IPF2944.2|Contig4-3019_0025|orf6.4604|CA2636|CaO19.4299|CaO19.11775 Protein likely to be essential for growth, based on an insertional mutagenesis strategy; similar to S. cerevisiae Msw1p, which is mitochondrial tryptophanyl-tRNA synthetase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 622530 622886 - ntar_904 622530 622886 1 622886 622530 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 623325 626096 + orf19.4301 623325 626096 1 623325 626096 623550 625994 orf19.11777|IPF22936.1|IPF19954.1|Contig4-3019_0031|Contig4-3019_0032|orf6.4606|CA2637|CaO19.11777|CaO19.4301|IPF19954 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 626046 628040 - orf19.4304 626046 628040 1 628040 626046 627851 626103 GAP1 orf19.11780|orf6.4609|IPF22960.1|IPF2936.1|GAP3|Contig4-3019_0033|CA2638|CaO19.4304|CaO19.11780 General amino acid permease; antigenic in human, mouse; 10-12 transmembrane regions; regulated by nitrogen source; alkaline, GlcNAc, phagocytosis upregulated; not required for virulence in mouse systemic infection; fungal-specific [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 628397 629119 - orf19.4305 628397 629119 1 629119 628397 629119 628397 orf19.11781|IPF23000.1|IPF2932.1|Contig4-2902_0001|orf6.4610|CA2639|CaO19.11781|CaO19.4305|IPF2932 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 629207 630336 + orf19.4305.1 629207 630336 2 629207|629436 629366|630336 629207 629716 IPF22928.1|IPF2930.1|Contig4-2902_0003|CA2640|IPF2930 ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 629652 630713 - orf19.4306 629652 630713 1 630713 629652 630575 629763 orf19.11782|IPF22994.1|IPF2929.2|Contig4-2902_0004|orf6.4611|CA2641|CaO19.4306|CaO19.11782|IPF2929 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 630820 631846 + orf19.4307 630820 631846 1 630820 631846 630820 631698 orf19.11783|IPF22992.1|IPF2927.2|Contig4-2902_0005|Contig4-2902_0006|orf6.4612|CA2642|CaO19.11783|DID2|CaO19.4307|FTI1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr5 631715 636835 - orf19.4308 631715 636835 1 636835 631715 636248 631860 HSL1 orf19.11784|IPF23021.1|IPF2926.2|Contig4-2902_0009|orf6.4613|CA2643|CaO19.4308|CaO19.11784 Probable protein kinase, involved in determination of morphology during the cell cycle of both yeast-form cells and hyphae via regulation of Swe1p and Cdc28p; required for full virulence and kidney colonization in mouse systemic infection [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 637362 637537 - ntar_905 637362 637537 1 637537 637362 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 637707 638822 + ntar_906 637707 638822 1 637707 638822 638391 638543 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 638411 640228 - orf19.4309 638411 640228 1 640228 638411 640030 639005 GRP2 orf19.11785|Contig4-2902_0012|GRE99|IPF18654.2|IPF2918.2|orf6.3162|orf6.4614|CA2644|GRE22|CaO19.4309 Similar to S. cerevisiae Gre2p (methylglyoxal reductase); antigenic in human; regulation associated with azole resistance; induced in core stress response or by oxidative stress (via Cap1p), fluphenazine, benomyl, or fluconazole (long term) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 640753 641235 - orf19.4310 640753 641235 1 641235 640753 641235 640753 IPF2915.2|IPF28467.1|Contig4-2902_0013|orf6.4615|CaO19.4310 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 641709 642431 + orf19.4311 641709 642431 1 641709 642431 641794 642249 YNK1 orf19.11786|IPF18653.1|IPF2914.1|Contig4-2902_0014|orf6.3163|orf6.4616|CA2645|CaO19.4311 Nucleoside diphosphate kinase (NDP kinase); homo-hexameric; soluble protein in hyphae; flucytosine induced; biofilm induced; macrophage-induced protein; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 642645 645130 + orf19.4312 642645 645130 1 642645 645130 642679 644991 orf19.11787|IPF16990.2|IPF2913.2|Contig4-2902_0015|orf6.3164|orf6.4617|CA1588|SPT8|CaO19.4312|CA1589|IPF16988|IPF16988.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 645058 647813 - orf19.4315 645058 647813 1 647813 645058 647571 645289 orf19.11790|IPF14665.2|IPF17806.3|Contig4-2700_0001|orf6.221|orf6.3167|CA1590|CaO19.4315|IPF14665 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 648153 648286 - ntar_907 648153 648286 1 648286 648153 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 648411 649944 + orf19.4316 648411 649944 1 648411 649944 648551 649741 orf19.11791|IPF14663.2|IPF19388.2|Contig4-2700_0002|orf6.222|orf6.3168|CA1591|BBH2|CaO19.4316|IPF14663 Trimethyllysine dioxygenase, the first enzyme in the carnitine biosynthesis pathway; hyphal-induced expression, regulated by Cyr1p, Ras1p, Efg1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 649741 650953 - orf19.4317 649741 650953 1 650953 649741 650942 649827 GRE3 orf19.11792|IPF22982.1|IPF14662.1|IPF14662|Contig4-2700_0003|orf6.3169|CA1592|CaO19.4317|CaO19.11792 Similar to D-xylose reductases; antigenic in murine systemic infection; soluble protein in hyphae; transcriptionally induced by macrophage interaction; transcriptionally induced by Mnl1p under weak acid stress, farnesol-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 651804 653828 - orf19.4318 651804 653828 1 653828 651804 653658 651946 MIG1 orf19.11793|IPF22963.1|IPF11048.2|Contig4-2700_0004|orf6.3170|CA1593|CaO19.11793|CaO19.4318 Transcriptional repressor; regulates genes for utilization of carbon sources; Tup1p-dependent and -independent functions; upregulated in biofilm; hyphal downregulated; caspofungin repressed; functional homolog of S. cerevisiae Mig1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 654510 654890 - orf19.4320 654510 654890 1 654890 654510 654890 654510 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 654609 654881 + ntar_908 654609 654881 1 654609 654881 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 654971 655423 - orf19.4321 654971 655423 1 655423 654971 655423 654971 orf19.11796|IPF23015.1|IPF11051.2|Contig4-2700_0008|orf6.3173|CA1594|CaO19.11796|CaO19.4321|IPF11051 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 654987 655277 + ntar_909 654987 655277 1 654987 655277 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 656835 659610 + orf19.4322 656835 659610 1 656835 659610 657008 659524 DAP2 orf19.11797|IPF18652.2|IPF11053.2|Contig4-2207_0003|orf6.3174|orf6.3264|CA1660|CaO19.4322 Protein described as dipeptidyl aminopeptidase; transcriptionally regulated during macrophage response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 659554 660260 - orf19.4323 659554 660260 1 660260 659554 660193 659690 orf19.11798|IPF23009.1|IPF11054.2|Contig4-2207_0002|orf6.3263|CA1659|CaO19.11798|YPT35|CaO19.4323|IPF11054 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 660359 661142 + orf19.4324 660359 661142 1 660359 661142 660407 660961 orf19.11799|IPF23005.1|IPF19924.1|orf6.3262|CA1658|CaO19.4324|CaO19.11799|IPF19924 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 660951 664647 - orf19.4325 660951 664647 1 664647 660951 664494 661063 orf19.11800|IPF23040.1|IPF16022.2|Contig4-2180_0004|Contig4-2207_0005|orf6.3261|CA1657|CaO19.11800|CaO19.4325|IPF16022 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr5 664825 667301 + orf19.4326 664825 667301 1 664825 667301 664935 666956 orf19.11801|IPF22949.1|IPF16019.2|Contig4-2180_0001|orf6.3260|CA1656|CaO19.11801|SNU66|CaO19.4326|IPF16019 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 667542 667921 - ntar_910 667542 667921 1 667921 667542 667755 667630 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 667696 671932 + orf19.4328 667696 671932 1 667696 671932 668063 671677 CCC2 orf19.11803|orf6.3258|IPF23037.1|IPF12705.2|CA1655|CaO19.4328|CaO19.11803 Copper-transporting P-type ATPase of Golgi; required for wild-type iron assimilation (indirect effect via Fet3p); induced by iron starvation, ciclopirox olamine; caspofungin repressed; not required for virulence in mouse systemic infection [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr5 672446 674542 + orf19.4330 672446 674542 1 672446 674542 672470 674542 IPF19738.1|IPF19702.1|Contig4-2329_0011|orf6.3256|orf6.1695|CA0646|CaO19.4330|IPF19702.5f|IPF19702 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 674361 676017 + orf19.4332 674361 676017 1 674361 676017 674379 675953 orf19.11806|IPF19702.1|IPF19737.2|Contig4-2329_0001|orf6.3254|orf6.1695|CA6283|CaO19.4332|IPF19702.3f Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr5 676508 677230 - orf19.4334 676508 677230 1 677230 676508 677230 676508 PGA58 orf19.11809|IPF22998.1|IPF19706.1|Contig4-2329_0005|Contig4-2329_0006|orf6.1698|CA0647|CaO19.11809|CaO19.4334|IPF19706 Putative GPI-anchored protein of unknown function; transcription is positively regulated by Tbf1p [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr5 678122 678368 + ntar_911 678122 678368 1 678122 678368 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 679406 681214 - orf19.4335 679406 681214 1 681214 679406 681090 679558 TNA1 orf19.11811|IPF17857.3|IPF11694.2|Contig4-1971_0004|orf6.1676|orf6.729|CA0164|TNA11|CaO19.4335|IPF11694 Putative nicotinic acid transporter; fungal-specific (no human or murine homolog); detected at germ tube plasma membrane by mass spectrometry; transcriptionally induced upon phagocytosis by macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 682952 683869 + orf19.4336 682952 683869 1 682952 683869 683005 683682 RPS5 orf19.11812|IPF11696.1|IPF28464.1|Contig4-2570_0018|orf6.1675|CA0632|CaO19.11812|CaO19.4336 Predicted ribosomal protein; macrophage/pseudohyphal-induced after 16 h; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 683935 686191 - orf19.4337 683935 686191 1 686191 683935 686001 684064 orf19.11813|IPF11698.1|IPF11341.2|IPF18701.2|Contig4-2570_0014|Contig4-2570_0016|orf6.1674|orf6.2794|orf6.2795|CA6284|CA0631|orf19.4338|IPF11698.3f Predicted membrane transporter, member of the monocarboxylate porter (MCP) family, major facilitator superfamily (MFS) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr5 687445 688978 + orf19.4339 687445 688978 1 687445 688978 687547 688866 VPS4 orf19.11814|IPF11700.3|IPF11343.2|Contig4-2570_0009|Contig4-2570_0010|orf6.1673|orf6.2796|CA1340|CaO19.4339 Protein involved in transport from multivesicular body (MVB) to the vacuole; mutation causes decreased SAP secretion and decreased virulence in murine intravenous infection; regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 688876 690159 - orf19.4340 688876 690159 1 690159 688876 690022 689024 orf19.11815|IPF22988.1|IPF11344.1|Contig4-2570_0008|orf6.2797|CA1341|CaO19.4340|CaO19.11815|IPF11344 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 689877 690469 + ntar_912 689877 690469 1 689877 690469 689877 690176 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 690285 691173 - orf19.4340.1 690285 691173 2 691173|691016 691091|690285 691099 690642 IPF11349.2|IPF11347.1|Contig4-2570_0003|CA1342|IPF11347 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 691244 693134 + orf19.4341 691244 693134 1 691244 693134 691336 692784 orf19.11816|IPF18885.1|IPF11353.2|Contig4-2186_0009|orf6.2798|orf6.1849|CDC91|CaO19.4341|CA0739|IPF18885 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 695066 696176 - ntar_913 695066 696176 1 696176 695066 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 697259 698800 + orf19.4342 697259 698800 1 697259 698800 697397 698467 orf19.11817|IPF11357.2|IPF14623.2|Contig4-2344_0008|orf6.1848|orf6.2799|CA1344|CaO19.4342|IPF14623 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 699494 705996 - orf19.4346 699494 705996 1 705996 699494 705913 699638 orf19.11823|IPF19511.2|IPF28465.1|Contig4-2617_0002|orf6.1844|orf6.2802|orf6.394|orf6.3990|orf6.446|CA2192|SEC16|CaO19.4346|CA0737|SEC16.53f.eoc|IPF19510.1|CA0738|SEC16.3f|orf6.1846|IPF14620.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 707622 708497 + ntar_914 707622 708497 1 707622 708497 707779 708033 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 708703 709318 + ntar_915 708703 709318 1 708703 709318 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 709445 712297 + orf19.4347 709445 712297 1 709445 712297 709994 711913 orf19.11824|PRR1|IPF14273.2|IPF19462.2|Contig4-2514_0005|orf6.3991|orf6.50|CA2193|CaO19.4347|IPF14273 Predicted ORF in Assemblies 19, 20 and 21; Hog1p-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 712524 712700 + ntar_916 712524 712700 1 712524 712700 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 712811 716820 + orf19.4348 712811 716820 1 712811 716820 712921 716733 orf19.11825|IPF14271.2|IPF28478.1|Contig4-2514_0001|Contig4-2514_0002|orf6.3992|CA2194|RGR1|CaO19.4348 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=G scenario_last_exon=G] Ca21chr5 716757 719730 - orf19.4349 716757 719730 1 719730 716757 719339 716895 orf19.11827|IPF16819.2|IPF28451.1|orf6.3993|orf6.3994|KRE2.3F|CA2195|CaO19.4349|IPF18517|CA2196|IPF18517.5f|IPF18517.1|IPF18517.3f Protein of unknown function, transcription is repressed in the presence of elevated CO2; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 721017 721558 + ntar_1412 721017 721558 2 721017|721144 721044|721558 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 726085 728208 - orf19.2657 726085 728208 1 728208 726085 728208 726085 orf19.10180|IPF24686.1|IPF16538.3|CaO19.2657|CaO19.10180 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 731670 733492 + orf19.2655 731670 733492 1 731670 733492 731837 732958 BUB3 orf19.10178|IPF19171.2|IPF10586.2|Contig4-2474_0008|orf6.1509|orf6.722|CA0526|CaO19.10178|CaO19.2655 Protein similar to S. cerevisiae Bub3p, which is a kinetochore checkpoint component; induced under hydroxyurea treatment [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 734543 736504 + orf19.2654 734543 736504 1 734543 736504 734722 736380 RMS1 orf19.10177|IPF10588.2|IPF29036.1|Contig4-2474_0006|orf6.3349|orf6.721|CA0161|CaO19.2654|IPF10588.1 Protein induced during the mating process [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 736908 740365 - orf19.2653 736908 740365 1 740365 736908 740200 736919 orf19.10176|IPF14652|IPF24706.1|IPF14652.2|Contig4-2474_0003|orf6.3350|CA1721|CaO19.2653|CaO19.10176 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr5 741779 742464 + orf19.2652 741779 742464 1 741779 742464 741779 742438 TEF4 orf19.10175|IPF24694.1|IPF16861.2|Contig4-2002_0002|orf6.3351|CA1722|CaO19.2652|CaO19.10175|TEF41 Putative translation elongation factor; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr5 742827 744318 + orf19.2651 742827 744318 1 742827 744318 742856 744115 CAM1-1 orf19.10174|IPF24690.1|IPF16860.2|Contig4-2002_0004|orf6.3352|CA1723|CaO19.2651|CAM1|CaO19.10174|TEF4 Putative translation elongation factor; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 744185 744761 - orf19.2650.1 744185 744761 1 744761 744185 744620 744333 IPF24703.1|IPF18618.1|CA1724|MRP10 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 745031 747658 - orf19.2650 745031 747658 1 747658 745031 747470 745173 orf19.10173|IPF19008.2|IPF15985.1|Contig4-2161_0002|Contig4-2161_0003|orf6.3353|CA1725|CaO19.2650|IPF15985 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr5 748618 750154 - orf19.2649 748618 750154 1 750154 748618 750012 748891 PCL1 orf19.10172|IPF16634.2|IPF29037.1|Contig4-2161_0007|orf6.1258|orf6.3354|CA0384|CaO19.2649 Cyclin homolog; expression induced upon filamentous growth; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr5 753873 755934 - orf19.2647 753873 755934 1 755934 753873 755770 754184 ZCF14|orf19.10170|IPF18551.2|IPF13021.1|Contig4-2669_0003|orf6.3356|orf6.3816|orf6.1256|CA1726|CaO19.2647|IPF13021 Putative transcription factor with zinc cluster DNA-binding motif; caspofungin induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr5 756022 759826 - orf19.2646 756022 759826 1 759826 756022 759778 756050 ZCF13|orf19.10169|orf6.3817|HAP1|IPF13024.2|IPF29039.1|Contig4-2669_0005|orf6.3357|CA2064|CaO19.2646|IPF13024 Predicted zinc-finger protein of unknown function, not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 760524 760844 + orf19.2645 760524 760844 1 760524 760844 760524 760844 orf19.10168|IPF24704.1|IPF29040.1|orf6.3818|CaO19.2645|CaO19.10168 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 761928 763319 + orf19.2644 761928 763319 1 761928 763319 762003 763127 QCR2 orf19.10167|IPF24692.1|IPF6978.2|Contig4-2912_0002|orf6.3819|CA2065|CaO19.2644|CaO19.10167 Protein described as ubiquinol-cytochrome-c reductase; antigenic in human; transcriptionally induced by interaction with macrophage; repressed by nitric oxide; in detergent-resistant membrane fraction (possible lipid raft component) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 763417 764240 + orf19.2643 763417 764240 1 763417 764240 763528 764001 orf19.10166|IPF24698.1|IPF6977.1|Contig4-2912_0005|orf6.3820|CA2066|RPO26|CaO19.2643|CaO19.10166 Putative protein of unknown function; heterozygous null mutant exhibits resistance to parnafungin in the C. albicans fitness test; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 764049 764788 - orf19.2642 764049 764788 1 764788 764049 764706 764191 orf19.10165|IPF24696.1|IPF6976.1|Contig4-2912_0006|orf6.3821|CA2067|CaO19.10165|CaO19.2642|IPF6976 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 764856 766407 + orf19.2641 764856 766407 1 764856 766407 764935 766179 ARP1 orf19.10164|IPF24691.1|IPF6975.2|Contig4-2912_0007|orf6.3822|CA2068|CaO19.10164|CaO19.2641 Protein described as centractin; induced upon adherence to polystyrene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 765923 766971 - orf19.2640 765923 766971 1 766971 765923 766939 766283 FUR1 orf19.10163|IPF24695.1|IPF6973.2|Contig4-2912_0008|orf6.3823|CA2069|CaO19.2640|CaO19.10163 Uracil phosphoribosyltransferase; enzyme of pyrimidine salvage; predicted tetrameric enzyme; mutations are associated with resistance to flucytosine (5-FC) in clinical isolates (clade I); macrophage-induced protein; flucytosine induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 767130 767821 - orf19.2639.1 767130 767821 3 767821|767689|767396 767776|767467|767130 767784 767257 IPF24685.1|IPF6971.2|Contig4-2912_0010|CA2071|orf19.2639.2|IPF6971|CA2070|IPF6971.3|IPF6972.2|IPF6971.53 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 767978 768788 - orf19.2639 767978 768788 1 768788 767978 768671 768150 orf19.10162|IPF24697.1|IPF6970.1|Contig4-2912_0012|orf6.3824|CA2072|CaO19.2639|MRPL20|CaO19.10162|IPF6970 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 769641 769734 + te(uuc)5 769641 769734 2 769641|769700 769677|769734 tE(UUC)5.2 tRNA-Glu predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 771938 772868 + orf19.2638 771938 772868 1 771938 772868 772041 772868 orf19.10161|IPF6967.2|IPF18967.2|Contig4-2912_0019|orf6.1459|orf6.3825|CA2073|CaO19.2638|IPF6967 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr5 775408 775911 + ntar_917 775408 775911 1 775408 775911 775495 775710 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 776107 777509 + ntar_918 776107 777509 1 776107 777509 776249 776377 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 777290 778445 - orf19.2637 777290 778445 1 778445 777290 778356 777343 orf19.10160|IPF24693.1|IPF6961.1|Contig4-2912_0024|orf6.1458|CA0490|PER1|CaO19.2637|CaO19.10160|COS161 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 778647 780292 - orf19.6654 778647 780292 1 780292 778647 780239 778743 orf19.10159|IPF24699.1|IPF6960.2|IPF2275.2|Contig4-2912_0026|orf6.1457|orf6.6763|CA0489|CA4262|orf19.2636|CaO19.6654|FMP422|IPF2275.5eoc|IPF2275 Predicted membrane transporter, member of the L-amino acid transporter-3 (LAT3) family, major facilitator superfamily (MFS) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 780561 782503 - orf19.6656 780561 782503 1 782503 780561 782254 780689 DUR3 IPF2277.1|Contig4-3038_0003|orf6.6765|CA4263|CaO19.6656|IPF2277 Putative protein of unknown function, transcription is upregulated in clinical isolates from HIV+ patients with oral candidiasis; alkaline downregulated; amphotericin B induced; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 782589 784422 - orf19.6658 782589 784422 1 784422 782589 784369 782738 orf6.6767|CA4264|CaO19.6658|IPF2280|IPF2280.1 Predicted ORF from Assembly 19; removed from Assembly 20; subsequently reinstated in Assembly 21 based on comparative genome analysis; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 785493 787414 + orf19.6659 785493 787414 1 785493 787414 785575 787305 GAP6 IPF2282.1|GAP5|Contig4-3038_0008|orf6.6768|CA4265|CaO19.6659|GAP22 Putative general amino acid permease; Plc1p-regulated; Gcn4p-regulated; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr5 787684 790056 - orf19.6660 787684 790056 1 790056 787684 789259 787718 IPF2283.1|Contig4-3038_0009|orf6.6769|CA4266|CaO19.6660|IPF2283 Putative protein of unknown function; mRNA binds to She3p; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 788909 789285 + ntar_919 788909 789285 1 788909 789285 788994 789143 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 790433 790669 + ntar_920 790433 790669 1 790433 790669 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 791043 792218 + orf19.6661 791043 792218 1 791043 792218 791043 792218 orf6.6770|CA4267|CaO19.6661|IPF2286|IPF2286.1 [NOT TRANSCRIBED?] Predicted ORF from Assembly 19; removed from Assembly 20; subsequently reinstated in Assembly 21 based on comparative genome analysis [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 792326 793088 - orf19.6662 792326 793088 1 793088 792326 793045 792500 IPF2287.1|Contig4-3038_0011|orf6.6771|CA4268|CaO19.6662|IPF2287 Putative protein of unknown function, transcription is upregulated in clinical isolates from HIV+ patients with oral candidiasis; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 793466 794186 - orf19.6663 793466 794186 2 794186|793784 794138|793466 793783 793466 RPS25B IPF2288.1|RPS25|Contig4-3038_0012|orf6.6772|CA4269|CaO19.6663 Predicted ribosomal protein; macrophage/pseudohyphal-induced after 16 h; downregulated upon phagocytosis by murine macrophage; transcription is positively regulated by Tbf1p; intron in 5'-UTR [label_first_exon=CGDmod label_last_exon=CGD orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr5 794439 797057 + orf19.6665 794439 797057 1 794439 797057 794500 796920 IPF2295.2|Contig4-3038_0014|Contig4-3038_0016|orf6.6774|CA4270|CaO19.6665|NIUP2|NUP2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr5 797382 798059 + orf19.6667 797382 798059 1 797382 798059 797458 797964 IPF2297.1|Contig4-3038_0018|orf6.6776|CA4271|CaO19.6667|IPF2297|SAP30 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 798292 799011 + orf19.6668 798292 799011 1 798292 799011 798397 798906 IPF2299.2|Contig4-3038_0020|orf6.6777|CA4272|CaO19.6668|CUE1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 798902 800509 - orf19.6670 798902 800509 1 800509 798902 800389 799007 CAC2 IPF2301.1|Contig4-3038_0022|orf6.6779|CA4273|CaO19.6670 Predicted ORF in Assemblies 19, 20 and 21; macrophage-induced gene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 801008 802876 + orf19.6671 801008 802876 1 801008 802876 801111 802847 LAP4 IPF2303.2|Contig4-3038_0025|orf6.6780|CA4274|LAP5|CaO19.6671|LAP42 Protein similar to aminopeptidase I; mutation confers hypersensitivity to amphotericin B; transcriptionally regulated during macrophage response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 803095 804880 + orf19.6672 803095 804880 1 803095 804880 803173 804639 IPF2305.2|Contig4-3038_0027|orf6.6781|CA4275|MDJ1|CaO19.6672 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 805327 807242 + orf19.6673 805327 807242 1 805327 807242 805379 807067 HEX1 IPF2308.1|Contig4-2760_0001|orf6.6782|CA4276|CaO19.6673 Beta-N-acetylhexosaminidase (beta-N-acetylglucosaminidase/chitobiase), highly glycosylated enzyme that is secreted to the periplasm and to the culture medium; required for full virulence; may have role in scavenging for carbon or nitrogen [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 807614 808995 + orf19.6674 807614 808995 1 807614 808995 807724 808722 BTS1 IPF2309.1|Contig4-2760_0002|Contig4-2760_0003|orf6.6783|CA4277|CaO19.6674 Decreased transcription is observed upon benomyl treatment [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 808440 809297 - ntar_921 808440 809297 1 809297 808440 809297 808719 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 809408 810741 + orf19.6676 809408 810741 1 809408 810741 809408 810307 IPF2311.2|Contig4-2760_0004|orf6.6785|orf6.6791|CA4279|CaO19.6676|DPH51 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr5 810519 811706 - orf19.6678 810519 811706 1 811706 810519 811706 810585 IPF2313.1|Contig4-2628_0003|orf6.6787|CA4280|AES4|CaO19.6678|IFJ5 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr5 811943 812284 - ntar_922 811943 812284 1 812284 811943 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 812331 812561 + ntar_923 812331 812561 1 812331 812561 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 813286 814610 - orf19.6679 813286 814610 1 814610 813286 814416 813556 IPF2314.1|Contig4-2628_0002|orf6.6788|CA4281|CaO19.6679|ALD98|IPF2314 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 815509 816179 + ntar_924 815509 816179 1 815509 816179 815689 815964 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 815915 816045 - ntar_925 815915 816045 1 816045 815915 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 816336 819242 + orf19.6680 816336 819242 1 816336 819242 816610 818973 FGR27 IPF2319.1|Contig4-2760_0008|orf6.6789|CA4282|CaO19.6680|IPF2319 Putative transcription factor with zinc cluster DNA-binding motif; lacks an ortholog in S. cerevisiae; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 819209 819479 - ntar_926 819209 819479 1 819479 819209 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 819790 821205 + orf19.6681 819790 821205 1 819790 821205 819927 821171 IPF2321.2|Contig4-2760_0006|orf6.6790|CA4283|AES5|CaO19.6681|IFJ4 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 821099 822235 - orf19.1124.2 821099 822235 1 822235 821099 822235 821336 IPF26215.1|IPF2323.3|IPF2322.2|CA4284|orf19.6682 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr5 822427 822701 + ntar_927 822427 822701 1 822427 822701 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 822454 823488 - orf19.1124 822454 823488 1 823488 822454 823432 822548 orf19.8722|IPF26195.1|IPF2326.2|orf6.1199|CA0361|CaO19.8722|CaO19.1124|IPF2326 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 823390 823564 + ntar_928 823390 823564 1 823390 823564 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 823514 823867 - orf19.1123 823514 823867 1 823867 823514 823867 823514 orf19.8721|IPF26211.1|IPF29575.1|orf6.1198|CaO19.8721|CaO19.1123 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 824264 825106 + orf19.1122 824264 825106 1 824264 825106 824264 825106 orf19.8720|IPF2328.2|IPF13870.2|Contig4-1915_0004|orf6.1197|orf6.3474|CA0360|HWH1|CaO19.1122|IPF2328 Predicted ORF in Assemblies 19, 20 and 21; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 825497 826537 + orf19.1121 825497 826537 1 825497 826537 825621 826442 orf19.8719|IPF2329.1|IPF13871.1|Contig4-1915_0003|Contig4-1995_0007|Contig4-1995_0008|orf6.1196|orf6.3473|CA1813|HWH2|CaO19.1121|IPF2329 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 829324 830274 + orf19.1120 829324 830274 1 829324 830274 829537 829962 FAV2 orf19.8718|IPF26203.1|IPF13879.2|Contig4-1995_0001|orf6.3472|CA1812|CaO19.1120|IPF13879 Induced by mating factor in MTLa/MTLa opaque cells; greater mRNA abundance observed in a cyr1 homozygous null mutant than in wild type; filament induced; regulated by Nrg1p, Rfg1p, Tup1p; possibly spurious ORF (AWG prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 830497 833640 - orf19.1119 830497 833640 1 833640 830497 833547 830668 MTR10 orf19.8717|IPF13881.3|IPF6321.2|orf6.3471|orf6.487|orf6.488|CA1811|CaO19.1119 Putative importin, member of a family of fungal-specific nuclear importins; transcription is regulated by Mig1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 833875 835174 - orf19.1117 833875 835174 1 835174 833875 835092 833953 orf19.8714|IPF19255.2|IPF6323.2|Contig4-2766_0017|orf6.3469|orf6.485|CA1810|FDH98|CaO19.1117|FDH2 Predicted ORF in Assemblies 19, 20 and 21; similar to Candida boidinii formate dehydrogenase; virulence-group-correlated expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 836020 837007 - orf19.1116 836020 837007 1 837007 836020 836896 836270 orf19.8713|IPF26198.1|IPF6325.2|Contig4-2766_0014|orf6.3468|CA1809|CaO19.1116|CaO19.8713|IPF6325 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 837223 837389 - ntar_929 837223 837389 1 837389 837223 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 837564 838445 + orf19.1115 837564 838445 1 837564 838445 837615 838256 GUK1 orf19.8712|IPF26196.1|IPF6326.2|Contig4-2766_0012|orf6.3467|CA1808|CaO19.8712|CaO19.1115 Putative guanylate kinase; identified in extracts from biofilm and planktonic cells; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr5 838451 839343 + orf19.1114 838451 839343 2 838451|838755 838637|839343 838594 839178 orf19.8711|IPF26204.1|IPF6328.2|Contig4-2766_0010|Contig4-2766_0011|orf6.3466|CA1807|IPF6328 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 839276 840183 - orf19.1113 839276 840183 1 840183 839276 840136 839369 orf19.8710|IPF26197.1|IPF6329.2|Contig4-2766_0009|orf6.3465|CA1806|CaO19.8710|CaO19.1113|IPF6329 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 840521 842930 - orf19.1112 840521 842930 1 842930 840521 842903 840609 BUD7 orf19.8709|IPF26191.1|IPF6332.2|Contig4-2766_0004|Contig4-2766_0006|orf6.3464|CA1805|CaO19.1112|CaO19.8709|IPF6332 Predicted ORF in Assemblies 19, 20 and 21; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 843191 843993 - orf19.1111 843191 843993 1 843993 843191 843951 843253 orf19.8708|IPF18669.1|IPF6333.3|Contig4-2766_0002|orf6.2987|orf6.3463|CA1804|CaO19.1111|TAF9|TAF17|IPF6333.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 844079 845230 + orf19.1110 844079 845230 1 844079 845230 844144 845136 orf19.8707|IPF6335.2|IPF6334.3|Contig4-2815_0022|Contig4-2815_0023|orf6.2986|CA1462|THI80|CaO19.1110 Thiamine pyrophosphokinase, phosphorylates thiamine to produce the coenzyme thiamine pyrophosphate (thiamine diphosphate); active as a homodimer [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr5 845419 846098 + orf19.1109 845419 846098 1 845419 846098 845545 845937 orf19.8706|IPF26205.1|IPF6338.1|Contig4-2815_0021|orf6.2985|CA1461|CaO19.1109|CaO19.8706|IPF6338 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 846250 846995 + orf19.1108 846250 846995 1 846250 846995 846299 846907 HAM1 orf19.8705|IPF26200.1|IPF6339.1|Contig4-2815_0019|orf6.2984|CA1460|CaO19.1108|CaO19.8705 Predicted ORF in Assemblies 19, 20 and 21; caspofungin repressed; regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 846870 847745 - orf19.1107 846870 847745 1 847745 846870 847685 847077 orf19.8704|IPF26199.1|IPF6340.2|Contig4-2815_0018|orf6.2983|CA1459|CaO19.8704|CaO19.1107|IPF6340 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 848338 848567 + ntar_930 848338 848567 1 848338 848567 848422 848550 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 848594 850948 - orf19.1106 848594 850948 1 850948 848594 850948 848594 orf19.8703|IPF26190.1|IPF6342.1|Contig4-2815_0016|Contig4-2815_0017|orf6.2982|CA1458|CaO19.8703|CaO19.1106|IPF6342 Predicted ORF in Assemblies 19, 20 and 21; shows Mob2p-dependent hyphal regulation; fluconazole-induced [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 855473 855730 - orf19.1105.3 855473 855730 1 855730 855473 855730 855473 IPF26207.1|IPF20047.1|Contig4-2815_0006|orf6.2981 ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 856534 857905 + orf19.1105.2 856534 857905 1 856534 857905 856605 856859 PGA56 IPF17002.3|IPF15957.2|Contig4-2815_0003|CSU51|CA0171|IPF15957 Regulator of sorbose utilization; putative GPI-anchor; predicted helix-loop helix domain; hyphal induced; induced during cell wall regeneration; shows colony morphology-related gene regulation by Ssn6p; transcription activated by Tbf1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 857655 858178 - orf19.1105 857655 858178 1 858178 857655 858178 857705 orf19.8701|IPF26202.1|IPF15959.2|Contig4-2815_0001|orf6.753|CA0170|CaO19.1105|CaO19.8701|IPF15959 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr5 858281 859210 - orf19.3220 858281 859210 1 859210 858281 859146 858541 orf19.10731|IPF24101.1|IPF14536.2|Contig4-2889_0006|orf6.3201|CA1617|CaO19.3220|CaO19.10731|IPF14536|IPF14536.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 859422 861837 - orf19.3219 859422 861837 1 861837 859422 861382 859577 orf19.10730|IPF24094.1|IPF14538.2|Contig4-2205_0004|Contig4-2205_0005|orf6.3200|CA1616|CaO19.3219|CaO19.10730|IPF14538 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr5 862376 862662 + ntar_931 862376 862662 1 862376 862662 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 863505 865243 - orf19.3218 863505 865243 1 865243 863505 865191 863725 orf19.10729|IPF14540|IPF24097.1|IPF14540.2|Contig4-2205_0008|orf6.3199|CA1615|CaO19.3218|CaO19.10729 Putative multidrug resistance protein; upregulated by Efg1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 868310 871435 + orf19.3216 868310 871435 1 868310 871435 868715 871219 orf19.10728|orf6.243|IPF18645.1|IPF12592.3|Contig4-2220_0003|orf6.3198|CA1614|CaO19.3216|IPF18645 Similar to Rab GTPase activators [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr5 871374 871612 - ntar_932 871374 871612 1 871612 871374 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 871896 873211 + orf19.3215 871896 873211 1 871896 873211 872183 872572 orf19.10727|IPF24104.1|IPF19735.1|Contig4-1643_0001|Contig4-1643_0002|orf6.3197|CA1613|CaO19.10727|CaO19.3215|IPF19735 Predicted ORF in Assemblies 19, 20 and 21; transcription is repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 873029 873588 - ntar_933 873029 873588 1 873588 873029 873588 873415 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 873713 875294 + orf19.3214 873713 875294 1 873713 875294 873713 875197 orf19.10726|IPF24098.1|IPF12814.2|Contig4-2443_0006|orf6.3196|CA1612|AES7|CaO19.10726|CaO19.3214|IFJ6 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr5 874447 874658 - ntar_934 874447 874658 1 874658 874447 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 876228 879074 + orf19.3213 876228 879074 1 876228 879074 876524 879022 orf19.10725|IPF24092.1|IPF12819.3|Contig4-2443_0003|orf6.3195|orf6.495|orf6.847|CA0094|CaO19.3213|IPF12819|IPF12819.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr5 879327 881130 + orf19.3212 879327 881130 1 879327 881130 879385 881061 MID1 orf19.10724|IPF12820.2|IPF19250.2|Contig4-2443_0001|orf6.496|orf6.848|CA0203|CaO19.3212 Putative stretch-activated Ca2+ channel of the high affinity calcium uptake system; role in thigmotropism; decreased transcription is observed upon fluphenazine treatment or in an azole-resistant strain with CDR1 and CDR2 overexpression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 881230 882539 + orf19.3211 881230 882539 2 881230|881404 881332|882539 881301 882415 RCF3 orf19.10723|IPF24099.1|IPF12401.3|Contig4-2463_0002|orf6.1701|orf6.849|CA0649|RFC3|CaO19.3211|IPF12401.2 Transcription is induced upon filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 882414 883072 - orf19.3210 882414 883072 1 883072 882414 883072 882434 orf19.10722|IPF24100.1|IPF12399.2|Contig4-2463_0004|orf6.1700|CA0648|CaO19.10722|CaO19.3210|IPF12399 Predicted ORF in Assemblies 19, 20 and 21; Plc1p-regulated; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr5 885950 886218 - ntar_935 885950 886218 1 886218 885950 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 886290 886786 + ntar_936 886290 886786 1 886290 886786 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 889368 889682 - orf19.3209 889368 889682 1 889682 889368 889682 889368 FGR42 IPF24103.1|IPF28845.1|Contig4-2463_0016|orf6.1699|CaO19.3209 [NOT TRANSCRIBED?] Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 889613 890103 + ntar_937 889613 890103 1 889613 890103 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 889976 890109 - ntar_938 889976 890109 1 890109 889976 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 890324 890833 + ntar_939 890324 890833 1 890324 890833 890586 890762 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 891209 892893 + orf19.1287 891209 892893 1 891209 892893 891567 892709 orf19.8874|IPF26046.1|IPF10595.1|orf6.4238|CA2362|CaO19.8874|CaO19.1287|IPF10595 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 896484 896840 - orf19.1286 896484 896840 1 896840 896484 896840 896484 orf19.8873|IPF26049.1|IPF29513.1|orf6.4239|CaO19.8873|CaO19.1286 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 898628 898949 + ntar_940 898628 898949 1 898628 898949 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 899327 902135 + orf19.1285 899327 902135 1 899327 902135 899327 902122 orf19.8872|IPF26042.1|IPF10590.2|orf6.4240|CA2363|CaO19.8872|CaO19.1285|IPF10590 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr5 902059 909145 - orf19.1283 902059 909145 1 909145 902059 909145 902168 MEC1 orf19.8870|IPF19757.1|IPF29511.1|Contig4-2808_0008|Contig4-2808_0009|Contig4-2808_0011|orf6.4242|CA2364|CaO19.1283 Protein described as cell cycle checkpoint protein; RNA abundance regulated by tyrosol and cell density [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr5 909205 910181 - orf19.1282 909205 910181 1 910181 909205 909921 909613 CKS1 orf19.8869|IPF26050.1|IPF10371.2|Contig4-2808_0007|orf6.4243|CA2365|CaO19.8869|CaO19.1282 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 910478 911593 - orf19.1281 910478 911593 1 911593 910478 911547 910882 orf19.8868|IPF26047.1|IPF10373.1|Contig4-2808_0006|orf6.4244|CA2366|CaO19.1281|CWC25|CaO19.8868|IPF10373 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 911695 912620 - orf19.1280 911695 912620 1 912620 911695 912410 912081 SUI1 orf19.8867|IPF10374.1|IPF29514.1|Contig4-2808_0003|orf6.4245|CA2367|CaO19.1280|CaO19.8867 Putative translation initiation factor; flucytosine induced; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 913787 915427 + orf19.1279 913787 915427 1 913787 915427 913853 915208 CDS1 orf19.8866|IPF26045.1|IPF16312.2|Contig4-2808_0002|orf6.874|CA0213|CaO19.8866|CaO19.1279 Protein similar to S. cerevisiae Cds1p; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 916681 918469 + orf19.3893 916681 918469 1 916681 918469 916885 918405 SCW11 orf19.11374|orf6.2346|IPF23274.1|IPF15862.2|CA1053|SCW11.3eoc Cell wall protein; transcription is decreased in mutant lacking ACE2; downregulated in core caspofungin response; transcriptionally regulated by iron; expression greater in high iron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 918379 919530 - orf19.3894 918379 919530 1 919530 918379 919520 918498 orf19.11375|IPF23270.1|IPF15861.1|Contig4-2459_0001|orf6.2345|CA1052|IOX1|CaO19.3894|IPF15861 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to toxic ergosterol analog [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 919668 921748 - orf19.3895 919668 921748 1 921748 919668 921556 919805 CHT2 orf19.11376|orf6.2344|IPF19719.2|IPF15860.2|Contig4-2459_0002|CA1051|CaO19.3895 Chitinase, required for normal filamentous growth; mRNA binds to She3p and is localized to buds of yeast-form cells and hyphal tips; downregulated in core caspofungin response; induced in yeast-form cells; Cyr1p-, Efg1p-, pH-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 924397 926012 + orf19.3897 924397 926012 1 924397 926012 924687 925949 orf19.11378|IPF23260.1|IPF19897.1|Contig4-2263_0011|orf6.2342|CA1050|CaO19.11378|CaO19.3897|IPF19897 Predicted ORF in Assemblies 19, 20 and 21; decreased transcription is observed upon fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2; transcription is repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 926458 927359 - orf19.3898 926458 927359 1 927359 926458 927296 926613 orf19.11379|IPF23297.1|IPF15393.2|Contig4-2263_0009|orf6.2341|CA1049|TLG1|CaO19.3898|CaO19.11379 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 926615 926999 + ntar_941 926615 926999 1 926615 926999 926615 926785 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 927456 928114 + orf19.3899 927456 928114 1 927456 928114 927539 927925 SDC1 orf19.11380|IPF18393.2|IPF15394.1|Contig4-2263_0007|orf6.2340|CA1048|CaO19.3899|IPF15394|CA3028|IPF18393|IPF18393.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 928149 930007 + orf19.3900 928149 930007 1 928149 930007 928268 929875 orf19.11381|IPF20126.1|IPF20071.1|Contig4-2263_0006|orf6.2339|orf6.5148|CA3027|UGO1|CaO19.3900|IPF20126 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 930330 932012 + orf19.3901 930330 932012 1 930330 932012 930439 931956 orf19.11382|IPF11499.2|IPF28558.1|Contig4-2263_0001|Contig4-2263_0003|orf6.5147|CA3026|CaO19.3901|SOX2|CaO19.11382|IFZ1|IPF11499.repeat1 Putative benzene desulfurase; induced by nitric oxide in yhb1 mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr5 930417 930659 - ntar_942 930417 930659 1 930659 930417 930641 930417 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 930607 931248 - ntar_943 930607 931248 1 931248 930607 930852 930607 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 931365 931798 - ntar_944 931365 931798 1 931798 931365 931798 931673 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 933709 934850 + orf19.3902 933709 934850 1 933709 934850 933782 934528 orf19.11383|IPF23291.1|IPF11503.1|Contig4-2296_0005|orf6.5146|CA3025|CaO19.3902|CaO19.11383|IPF11503 Predicted ORF in Assemblies 19, 20 and 21; decreased transcription is observed upon fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 936301 936888 + orf19.3903 936301 936888 1 936301 936888 936301 936888 orf19.11384|IPF23309.1|IPF11506.2|Contig4-2296_0001|orf6.5145|CA3024|CaO19.3903|CaO19.11384|IPF11506 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 937242 938012 - orf19.3904 937242 938012 1 938012 937242 938012 937242 orf19.11385|IPF23281.1|IPF11508.2|orf6.5144|CA3023|CaO19.11385|CaO19.3904|IPF11508 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 939322 939963 + orf19.3905 939322 939963 1 939322 939963 939322 939963 orf19.11386|IPF23298.1|IPF17642.2|Contig4-1931_0001|orf6.5143|CA3022|CaO19.3905|CaO19.11386|IPF17642 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 940701 941291 + orf19.3906 940701 941291 1 940701 941291 940701 941291 orf19.11387|IPF23302.1|IPF17640.2|orf6.5142|CA3021|CaO19.11387|CaO19.3906|IPF17640 Protein not essential for viability [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 942355 942666 - orf19.3907 942355 942666 1 942666 942355 942666 942355 orf19.11388|IPF23361.1|IPF28591.1|orf6.5141|CaO19.3907|CaO19.11388 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 943043 943657 + orf19.3908 943043 943657 1 943043 943657 943043 943657 orf19.11389|IPF23305.1|IPF15492.2|Contig4-2027_0003|orf6.5140|CA3020|CaO19.11389|CaO19.3908|IPF15492 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 944280 945558 + orf19.3910 944280 945558 1 944280 945558 944280 945521 orf19.11391|IPF23262.1|IPF15494.2|Contig4-2817_0009|orf6.5138|CA3019|CaO19.3910|RNY12|CaO19.11391|IPF15494 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr5 945576 947417 - orf19.3911 945576 947417 1 947417 945576 947362 946010 SAH1 orf19.11392|IPF23243.1|IPF10018.2|Contig4-2730_0002|orf6.5137|CA3018|CaO19.11392|CaO19.3911 Protein described as S-adenosyl-L-homocysteine hydrolase; predicted enzyme of sulfur amino acid metabolism; antigenic in human; biofilm-, alkaline-, fluconazole-induced expression; Gcn4p-regulated; amino acid starvation (3-AT) repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 947610 950128 - orf19.3912 947610 950128 1 950128 947610 949897 947849 GLN3 orf19.11393|IPF10021.2|IPF28549.1|Contig4-2730_0003|orf6.5136|CA3017|CaO19.3912|CaO19.11393|IPF10021 GATA transcription factor involved in regulation of filamentous growth induced by nitrogen starvation; regulates transcription of Mep2p ammonium permease; regulated by Gcn2p and Gcn4p; mRNA binds to She3p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 951897 953923 - orf19.3914 951897 953923 1 953923 951897 953387 952095 orf19.11396|IPF10027.2|IPF28563.1|Contig4-2194_0001|Contig4-2730_0010|orf6.5133|CA3016|CaO19.11396|CaO19.3914|IPF10027 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 954065 955939 - orf19.3915 954065 955939 1 955939 954065 955631 954174 orf19.11397|IPF10029.2|IPF18505.2|Contig4-2730_0012|orf6.4061|orf6.5132|CA2239|CaO19.3915|IPF10029.5eoc|CA3015|IPF10029 Predicted ORF in Assemblies 19, 20 and 21; Hog1p-induced; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr5 956013 958075 + orf19.3916 956013 958075 1 956013 958075 956373 957956 orf19.11398|orf19.11399|IPF23300.1|IPF12695.2|Contig4-2398_0001|Contig4-2730_0015|orf6.4060|orf6.4059|CA2238|CA2237|orf19.3917|IPF10032.5f|IPF10032.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 958000 960570 - orf19.3919 958000 960570 1 960570 958000 960282 958171 orf19.11401|IPF23216.1|IPF12694.2|Contig4-2398_0003|orf6.4057|CA2236|LPF25|CaO19.11401|CaO19.3919|IFA23 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 960657 961304 + orf19.3919.1 960657 961304 1 960657 961304 960781 961050 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 961465 962493 + orf19.3920 961465 962493 1 961465 962493 961504 962403 orf19.11402|IPF19135.2|IPF12689.1|Contig4-2398_0006|Contig4-2398_0008|orf6.4056|CA2235|MPD1|CaO19.3920 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 962378 963297 - orf19.3921 962378 963297 1 963297 962378 963291 962440 orf19.11403|IPF12688.2|IPF28566.1|Contig4-2398_0009|orf6.4055|orf6.824|CA0195|CaO19.3921|IPF12688 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 963378 964334 - orf19.3922 963378 964334 1 964334 963378 964315 963452 orf19.11404|IPF16228.2|IPF28565.1|Contig4-2398_0010|orf6.4054|orf6.823|CA0194|SDT1|CaO19.3922|IPF16228 Predicted ORF in Assemblies 19, 20 and 21; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 964546 965110 + ntar_945 964546 965110 1 964546 965110 964657 964785 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 965156 965875 - orf19.3923 965156 965875 1 965875 965156 965828 965202 PGA37 orf19.11405|IPF16226.2|IPF10922.2|Contig4-1606_0001|Contig4-1924_0002|orf6.4053|orf6.822|CA2234|CaO19.3923|IPF10922 Putative GPI-anchored protein of unknown function [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr5 966839 968192 - orf19.3924 966839 968192 1 968192 966839 968171 966936 orf19.11406|IPF10925.3|IPF10924.2|Contig4-2817_0014|orf6.4052|CA2233|CaO19.3924|AES3|CaO19.11406|IFJ3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=G scenario_last_exon=G] Ca21chr5 968454 968610 - ntar_946 968454 968610 1 968610 968454 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 968812 969173 - ntar_947 968812 969173 1 969173 968812 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 969897 970689 - orf19.3925 969897 970689 1 970689 969897 970682 970227 orf19.11407|IPF23304.1|IPF10929.1|Contig4-2817_0011|orf6.4051|CA2232|CaO19.3925|CaO19.11407|IPF10929 Putative protein of unknown function, transcription is activated in the presence of elevated CO2; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr5 971526 972946 + orf19.3926 971526 972946 1 971526 972946 971643 972842 orf19.11408|IPF23264.1|IPF10934.2|Contig4-2817_0009|orf6.4050|CA2231|RNY11|CaO19.3926|CaO19.11408|IPF10934 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 972853 974295 - orf19.3928 972853 974295 1 974295 972853 974251 973109 orf19.11410|IPF23263.1|IPF10936.2|Contig4-2817_0008|orf6.4048|CA2230|CaO19.3928|CaO19.11410|IPF10936 Putative transcription factor with zinc finger DNA-binding motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 974551 975788 + orf19.3929 974551 975788 1 974551 975788 974703 975740 orf19.11411|IPF14603.2|IPF28564.1|Contig4-2817_0007|orf6.1917|orf6.4047|CA0785|CaO19.3929|IPF14603|IPF14603.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 975529 976799 - orf19.3930 975529 976799 2 976799|976664 976734|975529 976772 975762 YUH2 orf19.11412|IPF23280.1|IPF14602.1|Contig4-2817_0006|orf6.1916|CA0784|CaO19.3930|UCT99|YUH1|CaO19.11412|YUH1.3 Predicted ORF in Assemblies 19, 20 and 21; described as similar to ubiquitin carboxyl-terminal hydrolases [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 976998 978180 - orf19.3931 976998 978180 1 978180 976998 977986 977075 SFC1 orf19.11413|IPF23279.1|IPF14601.2|Contig4-2817_0005|orf6.1915|CA0783|CaO19.11413|CaO19.3931|ACR1 Putative acyltransferase; alkaline upregulated; transcription is upregulated in both intermediate and mature biofilms [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 979125 979427 - orf19.3931.1 979125 979427 1 979427 979125 [NOT TRANSCRIBED?] Pseudogene; added to Assembly 21 based on comparative genome analysis [label_first_exon=CGD label_last_exon=CGD orf_changed=true scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 979462 979644 - orf19.3931.2 979462 979644 1 979644 979462 979644 979462 [NOT TRANSCRIBED?] ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 979789 980836 - orf19.3932 979789 980836 1 980836 979789 980773 979946 orf19.11414|IPF16253.2|IPF28567.1|Contig4-2817_0002|orf6.1914|CA0782|CaO19.3932|CaO19.11414|IPF16253 Predicted ORF in Assemblies 19, 20 and 21; induced in core caspofungin response; increased expression observed in ssr1 homozygous null mutant; induced by nitric oxide in yhb1 mutant; protein detected by mass spec in stationary phase culture [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 981211 981480 - orf19.3932.1 981211 981480 1 981480 981211 981480 981211 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 981760 982913 - orf19.3934 981760 982913 1 982913 981760 982845 981892 CAR1 orf19.11416|IPF16256.2|IPF10187.1|Contig4-2929_0002|orf6.1912|orf6.2297|CaO19.3934|CA1024|CA0781|CAR1.3eoc|IPF16256.1 Transcription is regulated by Nrg1p, Mig1p, and Tup1p; shows colony morphology-related gene regulation by Ssn6p; alkaline upregulated; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 983153 983455 + orf19.3935 983153 983455 1 983153 983455 983153 983455 orf19.11417|IPF23364.1|IPF28593.1|orf6.2298|CaO19.3935 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 983939 987786 + orf19.3936 983939 987786 1 983939 987786 984182 987670 orf19.11418|IPF23353.1|IPF10184.2|Contig4-2929_0005|Contig4-2929_0006|orf6.2299|CA1025|CaO19.3936|IPF10184 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to 5-fluorouracil (5-FU); induced upon biofilm formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 987867 989160 + orf19.3937 987867 989160 1 987867 989160 987898 989079 orf19.11419|IPF10824.3|IPF19645.1|Contig4-2929_0008|orf6.2300|orf6.3224|CA1026|TIP41.5f|IPF19645.exon1|IPF19646.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 989269 990304 + orf19.3938 989269 990304 1 989269 990304 989309 990097 orf19.11420|IPF10823.1|IPF10181.1|Contig4-2929_0009|orf6.2301|orf6.3225|CA1632|RSM26|CaO19.3938|IPF10181 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 990052 991096 - orf19.3940 990052 991096 1 991096 990052 991075 990173 orf19.11422|IPF10822.1|IPF10180.1|Contig4-2929_0011|orf6.2303|orf6.3227|CA1633|CaO19.3940|IPF10180 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 991162 992324 + orf19.3939 991162 992324 1 991162 992324 991305 992213 orf19.11421|IPF10820.1|IPF10179.1|Contig4-2929_0012|orf6.2302|orf6.3226|CA1634|CaO19.3939|IPF10179 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 992234 992648 - orf19.3940.1 992234 992648 1 992648 992234 CUP1 orf19.11422.1 Metallothionein, involved in copper resistance; transcription is induced by copper [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 993622 995597 - orf19.3941 993622 995597 1 995597 993622 995477 993756 URA7 orf19.11423|IPF23233.1|IPF10815.2|Contig4-2929_0016|orf6.3228|CA1635|CaO19.3941|CaO19.11423 Predicted ORF in Assemblies 19, 20 and 21; flucytosine induced; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 996112 996786 - orf19.3942 996112 996786 1 996786 996112 996764 996174 orf19.11424|IPF23299.1|IPF20086.1|Contig4-2929_0018|orf6.3229|CA1636|CaO19.3942|CaO19.11424|IPF20086 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 996868 997862 - orf19.3942.1 996868 997862 2 997862|997423 997795|996868 997796 997147 RPL43A IPF23373.1|IPF20087.1|Contig4-2929_0019|CA1637|RPL43A.3 Downregulated in the presence of human whole blood or polymorphonuclear (PMN) cells; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 998102 1000717 - orf19.3944 998102 1000717 1 1000717 998102 1000623 998281 GRR1 orf19.11426|IPF23206.1|IPF14608.2|Contig4-1767_0001|Contig4-1767_0003|Contig4-2929_0020|orf6.3231|CA1638|CaO19.3944|CaO19.11426 Protein involved in the negative control of pseudohyphal growth; ortholog of S. cerevisiae Grr1p, which is an F-box protein component of the SCF ubiquitin-ligase complex required for cell cycle progression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1002110 1003962 + orf19.3945 1002110 1003962 1 1002110 1003962 1002133 1003563 orf19.11427|IPF23250.1|IPF13799.3|Contig4-1800_0002|orf6.2412|CA1089|CaO19.3945|IPF13799|IPF13799.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1003598 1004811 - orf19.3946 1003598 1004811 1 1004811 1003598 1004698 1003703 orf19.11428|IPF23271.1|IPF13798.1|Contig4-1800_0004|orf6.2413|CA1090|CaO19.11428|COX18|CaO19.3946 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1004789 1005447 + orf19.3947 1004789 1005447 1 1004789 1005447 1004931 1005269 orf19.11429|IPF18764.2|IPF13796.2|Contig4-1800_0006|orf6.2414|CA1091|SPT4|CaO19.11429|CaO19.3947 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1005316 1009632 - orf19.3949 1005316 1009632 1 1009632 1005316 1009339 1005395 orf19.11431|IPF23338.1|IPF13795.2|orf6.2416|CA1092|CaO19.11431|YTA7|CaO19.3949 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1010130 1012073 - orf19.3950 1010130 1012073 1 1012073 1010130 1011998 1010265 MSM1 orf19.11432|IPF23232.1|IPF19722.1|orf6.2417|CA1093|CaO19.3950|CaO19.11432 Mitochondrial methionyl-tRNA synthetase (MetRS); functionally complements methionine auxotrophy of an E. coli MetRS mutant; transcription is regulated by Nrg1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 1012096 1013066 - orf19.3951 1012096 1013066 1 1013066 1012096 1012945 1012190 TIP1 orf19.11433|IPF18796.2|IPF16770.2|Contig4-1802_0003|orf6.2274|orf6.2418|CA1094|YIP1|CaO19.3951 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to toxic ergosterol analog [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 1013397 1015262 + orf19.3952 1013397 1015262 1 1013397 1015262 1013452 1015059 orf19.11434|IPF19895.1|IPF19901.2|Contig4-2292_0006|orf6.2275|orf6.2419|orf6.928|CA1011|CaO19.3952|SRP101 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1015142 1015483 - ntar_948 1015142 1015483 1 1015483 1015142 1015387 1015142 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 1015577 1019170 + orf19.3954 1015577 1019170 1 1015577 1019170 1015820 1019032 orf19.11436|IPF14208.2|IPF19402.2|Contig4-2292_0003|orf6.181|orf6.2277|CA1012|PSD2|CaO19.3954|PSD2.5f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1018996 1019557 - orf19.3954.1 1018996 1019557 1 1019557 1018996 1019362 1019123 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1020075 1022485 - orf19.3955 1020075 1022485 1 1022485 1020075 1022448 1020202 MES1 orf19.11437|IPF15550.2|IPF28546.1|Contig4-1832_0002|orf6.182|orf6.2278|CA1014|CaO19.3955 Cytoplasmic methionyl-tRNA synthetase (MetRS); has zinc-binding motif; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1022541 1024167 + orf19.3956 1022541 1024167 1 1022541 1024167 1022725 1024077 orf19.11438|IPF15547.2|IPF28562.1|Contig4-1832_0003|orf6.1120|orf6.2279|CA1015|CaO19.3956|IPF15547|IPF15547.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1023966 1025338 - orf19.3957 1023966 1025338 1 1025338 1023966 1025233 1024403 orf19.11439|IPF23282.1|IPF5793.2|orf6.1119|CA0318|FOL2|CaO19.3957 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 1025619 1029565 - orf19.3959 1025619 1029565 1 1029565 1025619 1029517 1025693 SSD1 orf19.11441|IPF18942.2|IPF5791.2|Contig4-3081_0004|orf6.1117|orf6.1554|CA0317|CaO19.3959 Protein with role in resistance to host antimicrobial peptides; virulence role in murine infection; functional homolog of S. cerevisiae Ssd1p, which suppresses various mutant phenotypes; constitutively expressed and not cell-cycle regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 1029737 1030133 - ntar_949 1029737 1030133 1 1030133 1029737 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 1030390 1030685 + ntar_950 1030390 1030685 1 1030390 1030685 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 1030786 1030986 + ntar_951 1030786 1030986 1 1030786 1030986 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 1030954 1032528 - orf19.3960 1030954 1032528 1 1032528 1030954 1032504 1031080 HYS2 orf19.11442|IPF23248.1|IPF5785.1|Contig4-3081_0006|orf6.1553|CA0555|CaO19.11442|CaO19.3960|CDC1 Predicted ORF in Assemblies 19, 20 and 21; cell-cycle regulated periodic mRNA expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 1032656 1034453 - orf19.3962 1032656 1034453 1 1034453 1032656 1034421 1032724 HAS1 orf19.11444|IPF5784.3|IPF28555.1|Contig4-3081_0007|Contig4-3081_0009|orf6.1551|orf6.3509|CA0554|CaO19.3962|IPF5784.2 Functional homolog of S. cerevisiae Has1p, which is a nucleolar protein of the DEAD-box ATP-dependent RNA helicase family that is involved in biogenesis of the ribosome, particularly the small (40S) subunit; caspofungin-downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 1035141 1035213 + ta(agc)5 1035141 1035213 1 1035141 1035213 tA(AGC)5.2 tRNA-Ala predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 1035347 1036534 + orf19.3963 1035347 1036534 1 1035347 1036534 1035482 1036357 orf19.11445|IPF23275.1|IPF5777.1|Contig4-3081_0010|orf6.3508|CA1838|CaO19.11445|FMP10|CaO19.3963|IPF5777 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1036656 1038181 + orf19.3964 1036656 1038181 1 1036656 1038181 1036689 1038089 ASH2 orf19.11446|IPF23249.1|IPF5776.1|Contig4-3081_0012|orf6.3507|CA1837|CaO19.3964|CaO19.11446|IPF5776|BRE2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1037529 1038840 - orf19.3965 1037529 1038840 1 1038840 1037529 1038824 1038084 orf19.11447|IPF18603.2|IPF5773.2|Contig4-3081_0013|orf6.3506|CA1836|CaO19.11447|CaO19.3965|IPF5773 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1039038 1040699 - ntar_952 1039038 1040699 1 1040699 1039038 1039930 1039682 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 1039173 1040687 + orf19.3966 1039173 1040687 1 1039173 1040687 1039173 1040687 CRH12 orf19.11448|IPF23240.1|IPF5772.2|Contig4-3081_0014|orf6.3505|CRH2|CA1835|CRH1|CaO19.11448|CaO19.3966 Putative cell wall protein, member of the CRH family; transcription is regulated by Nrg1p and Tup1p; alkaline upregulated by Rim101p; repressed during cell wall regeneration [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 1041040 1044322 + orf19.3967 1041040 1044322 1 1041040 1044322 1041235 1044198 PFK1 orf19.11449|IPF23197.1|IPF5769.1|Contig4-3081_0016|orf6.3504|CA1834|CaO19.11449|CaO19.3967 Alpha subunit of phosphofructokinase (PFK), which is Pfk1p, Pfk2p heteromultimer; PFK is activated by fructose 2,6-bisphosphate or AMP, inhibited by ATP; activity reduced on hyphal induction; phagocytosis-downregulated; fluconazole-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1051721 1052032 + orf19.3968 1051721 1052032 1 1051721 1052032 1051721 1052032 orf19.11451|IPF23347.1|IPF28582.1|orf6.2745|CaO19.3968|CaO19.11451 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 1053870 1056014 + orf19.3969 1053870 1056014 1 1053870 1056014 1053870 1056014 SFL2|orf19.11452|IPF8627.2|IPF28547.1|Contig4-3081_0036|orf6.2746|CA1309|IPF8627 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr5 1058007 1058968 - orf19.3970 1058007 1058968 1 1058968 1058007 1058879 1058136 orf19.11453|IPF23293.1|IPF13616.2|Contig4-3081_0042|orf6.5646|CA3395|CaO19.3970|CaO19.11453|IPF13616 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1059025 1060084 + orf19.3971 1059025 1060084 1 1059025 1060084 1059086 1059844 orf19.11454|IPF23290.1|IPF13617.2|Contig4-3081_0043|orf6.5647|CA3396|CaO19.11454|CaO19.3971|IPF13617 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr5 1059527 1060700 - orf19.3972 1059527 1060700 2 1060700|1060406 1060505|1059527 1060529 1060009 orf19.11455|IPF23326.1|IPF13618.1|Contig4-3081_0045|orf6.5648|CA3397|CaO19.11455|GOT1|CaO19.3972|IPF13618 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 1060248 1060587 + ntar_953 1060248 1060587 1 1060248 1060587 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 1061016 1062058 + orf19.3973 1061016 1062058 1 1061016 1062058 1061136 1061921 orf19.11456|IPF23285.1|IPF13621.2|Contig4-3081_0047|orf6.5649|CA3398|CaO19.11456|CaO19.3973|IPF13621 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1062037 1063991 - orf19.3974 1062037 1063991 1 1063991 1062037 1063882 1062095 PUT2 orf19.11457|IPF23228.1|IPF13622.2|Contig4-3081_0050|orf6.5650|CA3399|CaO19.11457|CaO19.3974 Alkaline upregulated; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1064178 1065459 - orf19.3976 1064178 1065459 1 1065459 1064178 1065391 1064270 orf19.11459|IPF23268.1|IPF13623.2|Contig4-3081_0052|orf6.5652|CA3400|JNM1|CaO19.3976|CaO19.11459 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 1065498 1066791 - orf19.3977 1065498 1066791 1 1066791 1065498 1066749 1065640 orf19.11460|IPF23267.1|IPF8652.2|orf6.5653|CA3401|CaO19.3977|CaO19.11460|IPF8652 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 1066924 1068103 + orf19.3978 1066924 1068103 1 1066924 1068103 1066976 1067689 orf19.11461|IPF23296.1|IPF8651.2|Contig4-1327_0001|orf6.5654|CA3402|CaO19.3978|CaO19.11461|IPF8651 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1067719 1073719 - orf19.3980 1067719 1073719 1 1073719 1067719 1073719 1067930 orf19.11463|IPF23311.1|IPF8650.2|Contig4-1327_0003|orf6.5656|CA3403|CaO19.11463|SLH1|CaO19.3980|IPF8650 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr5 1074239 1076005 - orf19.3981 1074239 1076005 1 1076005 1074239 1076005 1074239 MAL31 orf19.11464|IPF23226.1|IPF8647.2|orf6.5657|CA3404|CaO19.3981|CaO19.11464 Putative protein of unknown function, transcription is upregulated in clinical isolates from HIV+ patients with oral candidiasis; alkaline upregulated [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr5 1078944 1080692 + orf19.3982 1078944 1080692 1 1078944 1080692 1078944 1080692 orf19.11465|IPF23227.1|IPF8644.2|orf6.5658|CA3405|MAL32|CaO19.11465|CaO19.3982|IPF8644 Maltase; induced during growth on sucrose; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr5 1080802 1083156 - orf19.3983 1080802 1083156 1 1083156 1080802 1083059 1080849 orf19.11466|IPF23209.1|IPF9711.2|Contig4-2652_0007|orf6.5659|CA3406|CaO19.3983|CaO19.11466|IPF9711 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1083544 1083676 - ntar_954 1083544 1083676 1 1083676 1083544 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 1084318 1084655 + ntar_955 1084318 1084655 1 1084318 1084655 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 1084548 1084913 - ntar_956 1084548 1084913 1 1084913 1084548 1084913 1084770 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 1084795 1085323 + ntar_957 1084795 1085323 1 1084795 1085323 1085043 1085177 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 1086139 1086417 + ntar_958 1086139 1086417 1 1086139 1086417 1086198 1086326 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 1087139 1087395 + ntar_959 1087139 1087395 1 1087139 1087395 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 1087815 1088301 + ntar_960 1087815 1088301 1 1087815 1088301 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 1088526 1091148 + orf19.3984 1088526 1091148 1 1088526 1091148 1088560 1091088 orf19.11467|IPF19142.1|IPF18339.2|orf6.5660|orf6.7397|orf6.794|CA0184|IPF19142 Predicted ORF in Assemblies 19, 20 and 21; induced in core caspofungin response; increased expression observed in an ssr1 homozygous null mutant; induced by nitric oxide in yhb1 mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr5 1090199 1090404 - ntar_961 1090199 1090404 1 1090404 1090199 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 1091620 1094318 - orf19.3986 1091620 1094318 1 1094318 1091620 1094318 1091736 PPR1|orf19.11469|IPF19144.2|IPF9661.2|Contig4-2740_0001|orf6.7399|orf6.793|CA4758|CaO19.3986 Putative transcription factor with zinc cluster DNA-binding motif; has similarity to S. cerevisiae Ppr1p, which is a transcription factor involved in the regulation of uracil biosynthesis genes [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr5 1095702 1097429 + orf19.3988 1095702 1097429 1 1095702 1097429 1095702 1097429 orf19.11471|IPF23230.1|IPF9655.1|Contig4-2740_0007|orf6.7401|CA4759|CaO19.11471|CaO19.3988|IPF9655 Predicted ORF in Assemblies 19, 20 and 21; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 1096937 1097574 - ntar_962 1096937 1097574 1 1097574 1096937 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 1097663 1098363 + orf19.3990 1097663 1098363 1 1097663 1098363 1097705 1098196 orf19.11473|IPF23301.1|IPF9652.2|Contig4-2740_0008|orf6.7403|CA4760|CaO19.11473|CaO19.3990|IPF9652 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1098206 1100731 - orf19.3991 1098206 1100731 1 1100731 1098206 1100514 1098265 orf19.11474|IPF23210.1|IPF9651.2|Contig4-2740_0011|Contig4-2740_0012|orf6.7404|CA4761|CaO19.3991|CaO19.11474|IPF9650 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1100742 1101714 + orf19.3992 1100742 1101714 1 1100742 1101714 1101243 1101665 orf19.11475|orf6.7405|CaO19.11475|CaO19.3992 Predicted ORF from Assembly 19; removed from Assembly 20; subsequently reinstated in Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1101126 1102477 - orf19.3994 1101126 1102477 1 1102477 1101126 1102477 1101287 orf19.11477|IPF23265.1|IPF9647.2|Contig4-2740_0015|Contig4-2740_0016|Contig4-2740_0017|orf6.7407|CA4762|OST3|CaO19.3994|CaO19.11477|IPF9647 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 1102520 1104693 - orf19.3995 1102520 1104693 1 1104693 1102520 1104673 1102520 RIM13 orf19.11478|IPF23213.1|IPF9645.2|Contig4-2740_0018|orf6.7408|CA4763|CaO19.11478|CaO19.3995|IPF9645 Probable protease involved in the pH response pathway, likely to mediate activation of the transcription factor Rim101p via C-terminal cleavage; required for alkaline pH-induced hyphal growth and for normal levels of chlamydospore formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 1104773 1106355 + orf19.3996 1104773 1106355 1 1104773 1106355 1104781 1106229 orf19.11479|IPF23255.1|IPF19803.1|Contig4-2740_0019|orf6.7409|CA4764|CaO19.3996|GPI10 Putative mannosyltransferase; similar to S. cerevisiae Gpi10p; has HKEXRF motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1106223 1106516 - ntar_963 1106223 1106516 1 1106516 1106223 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 1107463 1109082 + orf19.3997 1107463 1109082 1 1107463 1109082 1107682 1108986 ADH1 orf19.11480|ADH|CAD|IPF13058.3|IPF17060.2|Contig4-2534_0002|Contig4-2534_0003|orf6.106|orf6.7410|CA4765|CaO19.3997 Alcohol dehydrogenase; at yeast-form but not hyphal cell surface; soluble in hyphae; immunogenic in human or mouse; complements S. cerevisiae adh1 adh2 adh3 mutation; regulated by growth phase, carbon source; fluconazole-, farnesol-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1109025 1109688 - orf19.3998 1109025 1109688 1 1109688 1109025 1109616 1109131 orf19.11481|IPF19441.2|IPF13056.2|Contig4-2534_0004|orf6.105|orf6.7411|CA4766|CaO19.3998|IPF13056 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1109694 1112533 + orf19.3999 1109694 1112533 1 1109694 1112533 1109886 1112189 orf19.11482|IPF23207.1|IPF13054.2|Contig4-2534_0009|orf6.7412|CA4767|CaO19.11482|CaO19.3999|IPF13054 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1118111 1121418 + orf19.4000 1118111 1121418 1 1118111 1121418 1119088 1121145 FIL2|orf19.11483|IPF23219.1|IPF9385.1|Contig4-2616_0006|Contig4-2616_0007|orf6.7413|CA4768|PHO2|CaO19.4000|CaO19.11483|IPF9385 Putative homeodomain transcription factor; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1121567 1122910 + orf19.4001 1121567 1122910 1 1121567 1122910 1121602 1122867 orf19.11484|IPF23254.1|IPF9384.2|Contig4-2616_0008|orf6.7414|CA4769|MSS2|CaO19.11484|CaO19.4001|IPF9384 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1122765 1124834 - orf19.4002 1122765 1124834 2 1124834|1124527 1124624|1122765 1124644 1122956 DUN1 orf19.11485|IPF23241.1|IPF9382.2|Contig4-2616_0009|orf6.7415|CA4770|IPF9382.3 Protein similar to S. cerevisiae Dun1p, which is a serine-threonine protein kinase involved in DNA damage cell-cycle checkpoint; induced under Cdc5p depletion [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 1125076 1127599 - orf19.4003 1125076 1127599 1 1127599 1125076 1127570 1125216 TIP20 orf19.11486|orf6.7416|IPF23205.1|IPF3336.2|Contig4-2616_0011|CA4771|CaO19.11486|CaO19.4003|IPF3336 Protein interacting with Sec20p, possibly involved in retrograde transport between the Golgi and the endoplasmic reticulum; similar to S. cerevisiae Tip20p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1127786 1129477 + orf19.4004 1127786 1129477 1 1127786 1129477 1127833 1129422 CCT3 orf19.11487|IPF23237.1|IPF3339.1|Contig4-3094_0053|orf6.7417|CA4772|CaO19.11487|CaO19.4004 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to cytochalasin D [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1129342 1130246 - orf19.4005 1129342 1130246 1 1130246 1129342 1130202 1129477 orf19.11488|IPF23294.1|IPF3340.2|Contig4-3094_0052|orf6.7418|YDR196|CA4773|CaO19.11488|CaO19.4005|IPF3340 Protein likely to be essential for growth, based on an insertional mutagenesis strategy [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1130303 1131495 + orf19.4006 1130303 1131495 1 1130303 1131495 1130323 1131381 orf19.11489|IPF23269.1|IPF3341.2|Contig4-3094_0050|orf6.7419|CA4774|CaO19.11489|CaO19.4006|IPF3341 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1130869 1132688 - orf19.4007 1130869 1132688 1 1132688 1130869 1132677 1131376 orf19.11490|IPF23257.1|IPF3342.1|Contig4-3094_0048|orf6.7420|CA4775|CaO19.4007|CaO19.11490|IPF3342 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 1132723 1133459 - orf19.4009 1132723 1133459 1 1133459 1132723 1133376 1132855 CNB1 orf19.11492|IPF23308.1|IPF3344.2|Contig4-3094_0046|orf6.7422|CA4776|CaO19.4009|CaO19.11492 Regulatory subunit of calcineurin B (Ca[2+]-calmodulin-regulated S/T protein phosphatase); required for wild-type resistance to fluconazole or to SDS; micafungin is fungicidal to null mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 1133780 1136105 + orf19.4010 1133780 1136105 1 1133780 1136105 1133879 1135975 PAN3 orf19.11493|IPF23217.1|IPF3345.2|Contig4-3094_0045|orf6.7423|CA4777|CaO19.11493|CaO19.4010 Protein not essential for viability; similar to S. cerevisiae Pan3p, which is a subunit of an RNAse complex that controls poly(A) tail length [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1137207 1138430 + orf19.4011 1137207 1138430 1 1137207 1138430 1137207 1138430 orf19.11494|IPF23261.1|IPF3348.1|Contig4-3094_0043|orf6.7424|CA4778|CaO19.4011|AES1|CaO19.11494|IFJ1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 1139119 1140384 + orf19.4012 1139119 1140384 1 1139119 1140384 1139318 1140232 PCL5 orf19.11495|IPF23278.1|IPF3351.1|Contig4-3094_0041|orf6.7425|CA4779|CaO19.4012|CaO19.11495|IPF3351 Protein similar to S. cerevisiae Pcl5p and other cyclins for Pho85p kinase; Gcn4p-induced; suppresses toxicity of C. albicans Gcn4p overproduction in S. cerevisiae via increased Pho85p-dependent phosphorylation and degradation of Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1140202 1141682 - orf19.4013 1140202 1141682 1 1141682 1140202 1141648 1140299 orf19.11496|IPF23252.1|IPF3352.2|Contig4-3094_0040|orf6.7426|CA4780|CaO19.11496|CaO19.4013|IPF3352 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1141911 1143390 + orf19.4014 1141911 1143390 1 1141911 1143390 1141942 1143390 orf19.11497|IPF3355|IPF23246.1|IPF3355.2|Contig4-3094_0038|orf6.7427|CA4781|CaO19.4014|CaO19.11497 Predicted ORF in Assemblies 19, 20 and 21; described as similar to S. cerevisiae Cdc1p; induced upon adherence to polystyrene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 1143550 1144967 + orf19.4015 1143550 1144967 1 1143550 1144967 1143585 1144874 CAG1 orf19.11498|IPF23259.1|IPF3356.2|Contig4-3094_0037|orf6.7428|GPA1|CA4782|CaO19.4015|CaO19.11498|GBA1 Alpha subunit of heterotrimeric G protein; positive role in mating pheromone response; more mRNA in opaque than white cells; transcriptionally repressed by MTLa1p-MTLalpha2p complex; regulated by hemoglobin-responsive Hbr1p via MTL genes [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 1144899 1146340 - orf19.4016 1144899 1146340 1 1146340 1144899 1146284 1144965 orf19.11499|IPF23251.1|IPF3358.2|Contig4-3094_0036|orf6.7429|CA4783|CaO19.4016|COR1|CaO19.11499|IPF3358 Predicted ORF in Assemblies 19, 20 and 21; amphotericin B induced; repressed by nitric oxide; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1146553 1147497 - orf19.4017 1146553 1147497 1 1147497 1146553 1147497 1146553 orf19.11500|IPF23276.1|IPF3359.2|Contig4-3094_0034|orf6.7430|CA4784|CaO19.11500|CaO19.4017|IPF3359 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr5 1147641 1148463 - orf19.4018 1147641 1148463 1 1148463 1147641 1148441 1147686 orf19.11501|IPF23288.1|IPF3361.2|Contig4-3094_0032|orf6.7431|CA4785|CaO19.4018|RSM7|CaO19.11501|IPF3361 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1148550 1149338 + orf19.4019 1148550 1149338 1 1148550 1149338 1148592 1149212 orf19.11502|IPF23286.1|IPF3362.2|Contig4-3094_0031|orf6.7432|CA4786|CaO19.11502|CaO19.4019|IPF3362 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1149220 1150180 - orf19.4021 1149220 1150180 1 1150180 1149220 1150168 1149257 orf19.11504|IPF23277.1|IPF3364.1|Contig4-3094_0029|orf6.7434|CA4787|CaO19.4021|CaO19.11504|IPF3364 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 1150261 1150833 - orf19.4022 1150261 1150833 1 1150833 1150261 1150803 1150309 SDH4 orf19.11505|orf6.7435|IPF23310.1|IPF3365.1|Contig4-3094_0028|CA4788|CaO19.4022|CaO19.11505|SDH42 Succinate dehydrogenase, membrane subunit; transcriptionally regulated by iron; expression greater in high iron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 1150874 1151429 - orf19.4023 1150874 1151429 1 1151429 1150874 1151322 1150975 MRP2 orf19.11506|IPF23339.1|IPF3366.1|Contig4-3094_0027|orf6.7436|CA4789|CaO19.11506|CaO19.4023|IPF3366 Protein similar to S. cerevisiae Mrp2p, which is a component of the small subunit of the mitochondrial ribosome; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 1151699 1152497 + orf19.4024 1151699 1152497 1 1151699 1152497 1151737 1152450 RIB5 orf19.11507|IPF23284.1|IPF3367.1|Contig4-3094_0026|orf6.7437|CA4790|CaO19.4024|CaO19.11507|IPF3367 Putative riboflavin synthase; fungal-specific (no human or murine homolog); farnesol-downregulated; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 1152573 1153289 + orf19.4025 1152573 1153289 1 1152573 1153289 1152595 1153185 PRE1 orf19.11508|IPF23307.1|IPF3370.2|Contig4-3094_0024|orf6.7438|CA4791|CaO19.11508|CaO19.4025|IPF3370 Upregulated by Rim101p at acid pH; flucytosine induced; amphotericin B repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 1153238 1154134 - orf19.4026 1153238 1154134 1 1154134 1153238 1154134 1153238 HIS1 orf19.11509|IPF23273.1|IPF3372.2|Contig4-3094_0023|orf6.7439|CA4792|CaO19.11509|CaO19.4026 ATP phosphoribosyl transferase; enzyme of histidine biosynthesis; fungal-specific (no human, murine homolog); upregulated in biofilm; acid upregulated/alkaline downregulated by Rim101p; regulated by Gcn2p, Gcn4p; strain CA9 is a his1 mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1154210 1155527 - orf19.4028 1154210 1155527 1 1155527 1154210 1155352 1154366 orf19.11511|IPF23272.1|IPF3375.1|Contig4-3094_0021|orf6.7441|CA4793|RER2|CaO19.11511|CaO19.4028|IPF3375 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1155662 1157079 + orf19.4029 1155662 1157079 1 1155662 1157079 1155795 1157042 orf19.11512|IPF23256.1|IPF3377.1|Contig4-3094_0019|orf6.7442|CA4794|CaO19.4029|SQT1|CaO19.11512 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 1157144 1158626 + orf19.4030 1157144 1158626 1 1157144 1158626 1157155 1158513 orf19.11513|IPF23253.1|IPF3378.2|Contig4-3094_0017|orf6.7443|CA4795|PRI1|CaO19.4030|CaO19.11513|IPF3378 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr5 1158471 1161251 - orf19.4031 1158471 1161251 1 1161251 1158471 1161237 1158544 orf19.11514|IPF23202.1|IPF3380.2|Contig4-3094_0016|orf6.7444|CA4796|CaO19.4031|CaO19.11514|IPF3380 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 1161384 1164407 - orf19.4033 1161384 1164407 1 1164407 1161384 1164407 1161417 PRP22 orf19.11516|IPF23374.1|IPF8801.2|Contig4-3094_0013|orf6.7446|CA4797|CaO19.4033|CaO19.11516 Protein described as an RNA-dependent ATPase; induced upon adherence to polystyrene; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 1164537 1166024 + orf19.4032 1164537 1166024 1 1164537 1166024 1164565 1165941 RPN5 orf19.11515|orf19.11517|IPF23283.1|IPF8798.1|Contig4-3094_0010|Contig4-3094_0011|orf6.7445|orf6.7447|CA4798|CA4799|orf19.4034|RPN5.3f Predicted ORF in Assemblies 19, 20 and 21; macrophage/pseudohyphal-repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1165873 1167357 - orf19.4035 1165873 1167357 1 1167357 1165873 1167315 1165960 PGA4 orf19.11518|IPF23247.1|IPF8796.1|Contig4-3094_0009|orf6.7448|CA4800|GAS1|CaO19.4035|CaO19.11518|IPF8796 GPI-anchored cell surface protein, similar to S. cerevisiae Gas1p; fungal-specific (no human or murine homolog); transcription is upregulated in RHE model of oral candidiasis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1168027 1169523 + orf19.4036 1168027 1169523 1 1168027 1169523 1168153 1169469 APM1 orf19.11519|IPF23258.1|IPF8795.1|Contig4-3094_0006|orf6.7449|CA4801|CaO19.11519|CaO19.4036 Phosphorylated protein similar to S. cerevisiae Apm1, which is involved in vesicle transport; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1169370 1171287 - orf19.4040 1169370 1171287 1 1171287 1169370 1171286 1169517 ILV3 orf19.11523|IPF7211.3|IPF8790.2|Contig4-3094_0005|orf6.4407|orf6.7453|CA4802|CaO19.4040 Putative dihydroxyacid dehydratase; fungal-specific (no human or murine homolog); upregulated in biofilm; S. cerevisiae ortholog is Gcn4p regulated; repressed by nitric oxide; macrophage-induced protein; farnesol-downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1172076 1172705 + orf19.4041 1172076 1172705 1 1172076 1172705 1172145 1172669 PEX4 orf19.11524|IPF8784.1|IPF7214.1|Contig4-3094_0004|orf6.4408|orf6.7454|CA4803|CaO19.4041 Predicted ORF in Assemblies 19, 20 and 21; transcription is upregulated in both intermediate and mature biofilms [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1172664 1174958 - orf19.4043 1172664 1174958 1 1174958 1172664 1174952 1172694 orf19.11525|IPF7217.2|IPF8783.3|Contig4-3094_0003|orf6.4409|orf6.7456|CA2489|CaO19.4043|IPF7217 Predicted ORF in Assemblies 19, 20 and 21; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr5 1175087 1175905 - orf19.4044 1175087 1175905 1 1175905 1175087 1175905 1175225 MUM2 orf19.11526|IPF23292.1|IPF7220.2|Contig4-3094_0002|orf6.4410|CA2490|CaO19.4044|CaO19.11526 Protein similar to S. cerevisiae Mum2p; transcription is induced in response to alpha pheromone in SpiderM medium; transcription is regulated by Tup1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 1175163 1175940 + ntar_964 1175163 1175940 1 1175163 1175940 1175697 1175882 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr5 1175955 1176490 - orf19.4046 1175955 1176490 1 1176490 1175955 1176416 1175955 orf19.11528|IPF23317.1|IPF7221.2|Contig4-3094_0001|orf6.4412|CA2491|CaO19.11528|CaO19.4046|IPF7221 Putative transcription factor containing a Zn(2)-Cys(6) binuclear cluster; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 1176415 1178294 + orf19.4045 1176415 1178294 1 1176415 1178294 1176415 1178253 EST1 orf19.11527|orf6.4411|IPF23224.1|IPF7224.2|Contig4-2715_0009|CA2492|CaO19.11527|CaO19.4045|IPF7224 Telomerase subunit; allosteric activator of catalytic activity, but not required for catalytic activity; has TPR domain [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 1178331 1179481 + orf19.4048 1178331 1179481 1 1178331 1179481 1178347 1179459 DES1 orf19.11530|IPF23266.1|IPF7227.2|Contig4-2715_0008|orf6.4414|CA2493|CaO19.11530|CaO19.4048|IPF7227 Putative delta-4 sphingolipid desaturase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 1179320 1180961 - orf19.4051 1179320 1180961 1 1180961 1179320 1180961 1179456 HTS1 orf19.11533|IPF23244.1|IPF7230.2|Contig4-2715_0007|orf6.4417|CA2494|CaO19.11533|CaO19.4051 Putative tRNA-His synthetase; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr5 1181018 1181652 + ntar_1414 1181018 1181652 2 1181018|1181315 1181134|1181652 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr5 1182169 1182927 - orf19.4054 1182169 1182927 1 1182927 1182169 1182927 1182169 CTA24 orf19.11536|IPF23289.1|IPF7233.2|Contig4-2715_0005|orf6.1799|orf6.4420|CA2495|TLO12|CaO19.4054|CTA213|CaO19.11536 Putative transcriptional activator, downregulated by Efg1p; member of a family of telomere-proximal genes; transcription is upregulated in an RHE model of oral candidiasis [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr5 1188461 1189117 - orf19.4055 1188461 1189117 1 1189117 1188461 1189117 1188806 orf19.11537|IPF23360.1|IPF3468.2|Contig4-2210_0004|orf6.4421|YBR075W|CA2496|CaO19.4055|CaO19.11537|IPF3468 Protein similar to S. cerevisiae Ybr075wp; transposon mutation affects filamentous growth; clade-associated gene expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr6 2 346 + orf19.6339 2 346 1 2 346 30 233 NRG2 IPF27436.1|orf6.5532 Protein similar to S. cerevisiae Nrg2p transcription factor, which regulates invasive growth in S. cerevisiae; transposon mutation affects filamentous growth [label_first_exon=CGD label_last_exon=CGD orf_changed=true scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 2916 3595 - ntar_965 2916 3595 1 3595 2916 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 3622 4008 + orf19.6338 3622 4008 1 3622 4008 3622 4008 IPF27434.1|Contig4-2210_0003|Contig4-3079_0032|orf6.5531|CaO19.6338 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 5545 6334 + orf19.6337 5545 6334 1 5545 6334 5545 6075 TLO13 IPF5711.1|IPF5712.1|Contig4-3048_0015|CA3298|TLO13b|CTA28.5f Member of a family of telomere-proximal genes of unknown function; may be spliced in vivo; overlaps orf19.6337.1, which is a region annotated as blocked reading frame [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr6 6934 7044 + tl(caa)5 6934 7044 2 6934|7001 6972|7044 tRNA-Leu predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 7282 9942 - orf19.6336 7282 9942 1 9942 7282 9900 7282 PGA25 orf19.7542|IPF5723.1|IPF5720.1|Contig4-3048_0011|orf6.5522|orf6.5529|CA3295|CaO19.6336|IPF5723|CA3296|IPF5723.exon2|IPF5723.exon1 Putative GPI-anchored protein of unknown function; fluconazole-downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chr6 7644 7901 + ntar_966 7644 7901 1 7644 7901 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 8392 10275 + ntar_967 8392 10275 1 8392 10275 8450 8851 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 10212 11445 - orf19.6329 10212 11445 1 11445 10212 11351 10266 IPF5723.1|IPF5720.1|Contig4-2795_0003|Contig4-2795_0004|orf6.5522|orf6.5529|CA3295|CaO19.6329|IPF5723|CA3296|IPF5723.exon2|IPF5723.exon1 Predicted ORF in Assemblies 19, 20 and 21; opaque-specific transcription; fluconazole-downregulated; greater mRNA abundance in a cyr1 homozygous null mutant than in wild type; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 11535 12026 + orf19.6328 11535 12026 1 11535 12026 11586 11954 IPF5725.1|Contig4-2795_0007|orf6.5521|CA3294|CaO19.6328|IPF5725 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 11802 12557 - orf19.6327 11802 12557 1 12557 11802 12549 11956 HET1 IPF5726.1|Contig4-2795_0008|orf6.5520|CA3293|CaO19.6327|IPF5726 Putative sphingomyelin transfer protein [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 12616 13439 - orf19.6326 12616 13439 1 13439 12616 13439 12654 IPF5729.1|Contig4-2795_0009|orf6.5519|CA3292|CaO19.6326|IPF5729 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 13524 13883 + orf19.6325.1 13524 13883 1 13524 13883 13539 13784 IPF5730.1|CA3291|IPF5730 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 13789 16046 - orf19.6324 13789 16046 1 16046 13789 16035 13798 VID27 IPF5734.2|Contig4-2795_0012|orf6.5517|CA3290|CaO19.6324|IPF5734 Protein similar to S. cerevisiae Vid27p; transposon mutation affects filamentous growth; mutation confers hypersensitivity to toxic ergosterol analog; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 16122 16828 - orf19.6323 16122 16828 1 16828 16122 16713 16135 HPA2 IPF14291.1|Contig4-2795_0013|orf6.5516|CA3289|CaO19.6323|HPA3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr6 17238 18237 + orf19.6322 17238 18237 1 17238 18237 17289 18134 ARD ARDH|ARD8|IPF14294.1|Contig4-2795_0014|orf6.5515|CA3288|ARD1|CaO19.6322 D-arabitol dehydrogenase, NAD-dependent (ArDH); enzyme of D-arabitol and D-arabinose catabolism; D-arabitol is a marker for active infection in humans; has conserved YXXXK motif of short-chain alcohol-polyol-sugar dehydrogenases [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 18348 18718 + orf19.6321 18348 18718 1 18348 18718 18362 18688 PGA48 orf6.5514|SPI1|IPF14295.1|Contig4-2795_0015|CA3287|CaO19.6321|IPF14295 Putative GPI-anchored protein of unknown function; similar to S. cerevisiae Spi1p, which is induced at stationary phase; transcriptionally regulated by iron; expression greater in high iron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 18597 20843 - orf19.6319 18597 20843 1 20843 18597 20661 18685 orf19.8766|IPF14298.2|orf6.815|orf6.5512|CA3286|orf19.1175|CaO19.6319|UBP3|UBP3.3eoc Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 20907 21553 - orf19.1178 20907 21553 1 21553 20907 21525 20920 orf19.8768|IPF18909.2|IPF15133.2|Contig4-2980_0001|orf6.1743|orf6.818|CA6185|CaO19.1178|IPF15133 Putative transcription factor with bZIP DNA-binding motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 21603 22973 + orf19.1177 21603 22973 1 21603 22973 21616 22896 orf19.8769|IPF26139.1|IPF15134.2|Contig4-2980_0004|orf6.1744|orf6.817|CA0192|RTT106|CaO19.1177|IPF15134 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 22640 23375 - orf19.1179 22640 23375 1 23375 22640 23292 22909 orf6.819|IPF19608.1|IPF19609.1|orf6.1745|CA0674|CaO19.1179|IPF19608 Transcriptionally regulated by iron; expression greater in high iron; possibly subject to Kex2p processing [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr6 23422 24711 + orf19.1180 23422 24711 1 23422 24711 23430 24677 orf19.8771|IPF13098.2|IPF19848.2|Contig4-2980_0007|orf6.1746|orf6.820|CA0675|CaO19.1180|IPF13098 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 24006 24861 - ntar_1428 24006 24861 2 24861|24665 24841|24006 24361 24101 [label_first_exon=CGD label_last_exon=CGD orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr6 24885 25973 + orf19.1181 24885 25973 1 24885 25973 24885 25973 orf19.8772|IPF13097.2|IPF29548.1|Contig4-2980_0009|orf6.1747|CA0676|CaO19.8772|CaO19.1181|IPF13097 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr6 25025 26874 - orf19.1182 25025 26874 1 26874 25025 26861 25968 orf19.8773|IPF13095.1|IPF13903.2|Contig4-2980_0011|orf6.1748|orf6.4619|CA0677|CaO19.1182|VAM7|IPF13095 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 26989 28678 + orf19.1183 26989 28678 1 26989 28678 27005 28651 orf19.8774|IPF13094.1|IPF13902.1|Contig4-2980_0013|orf6.1749|orf6.4620|CA0678|CaO19.1183|IPF13094 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 28774 30018 + orf19.1185 28774 30018 1 28774 30018 28800 29930 orf19.8776|IPF13090.3|IPF13899.2|Contig4-2980_0017|Contig4-2980_0018|orf6.1751|orf6.4622|orf6.515|CA2646|CaO19.1185|IPF13089 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr6 30077 31164 + orf19.1186 30077 31164 1 30077 31164 30104 30796 orf19.8777|IPF13897.2|IPF13088.1|Contig4-2980_0021|orf6.4623|orf6.516|CA2647|CaO19.1186|IPF13088 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 31319 31534 + ntar_968 31319 31534 1 31319 31534 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 31954 35300 + orf19.1187 31954 35300 1 31954 35300 32572 35133 CPH2 orf19.8778|IPF13893.3|IPF9062.2|Contig4-2980_0027|orf6.4624|orf6.517|CA2648|CaO19.1187|IPF9062 Transcriptional activator of hyphal growth; Myc bHLH family: directly regulates Tec1p, which regulates hypha-specific genes; probably homodimeric, phosphorylated; enhances S. cerevisiae nitrogen starvation-induced pseudohyphal growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 35482 35851 - ntar_969 35482 35851 1 35851 35482 35670 35482 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 38509 41926 + orf19.1189 38509 41926 2 38509|38816 38509|41926 39779 41833 orf19.8780|IPF19121.2|IPF9057.2|Contig4-2980_0031|orf6.4626|orf6.861|CA2649|CaO19.1189|IPF9057 Predicted ORF in Assemblies 19, 20 and 21; transcription regulated upon yeast-hyphal switch; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGD label_last_exon=CGDmod orf_changed=true scenario_first_exon=Z scenario_last_exon=A] Ca21chr6 43721 46900 - orf19.1190 43721 46900 1 46900 43721 46683 43852 orf19.8781|IPF9052.3|IPF13604.2|Contig4-3055_0026|orf6.4627|orf6.860|CA2650|CaO19.1190|VPH1|STV1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 47063 49731 + orf19.1191 47063 49731 1 47063 49731 47177 49597 orf19.8782|IPF26127.1|IPF13605.2|Contig4-3055_0024|orf6.4628|CA2651|HRD3|CaO19.8782|CaO19.1191 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 49565 53930 - orf19.1192 49565 53930 1 53930 49565 53930 49650 DNA2 orf19.8783|IPF26141.1|IPF15025.2|Contig4-3055_0023|orf6.2845|orf6.4629|CA2652|CaO19.1192|CaO19.8783 Protein similar to S. cerevisiae Dna2p, which is a DNA replication factor involved in DNA repair; induced under hydroxyurea treatment [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr6 54250 56189 - orf19.1193 54250 56189 1 56189 54250 56126 54387 GNP1 orf19.8784|AGP1|IPF7152.2|IPF29546.1|Contig4-3055_0022|orf6.2846|orf6.4630|GNP2|CA1373|CaO19.1193 Protein described as similar to asparagine and glutamine permease; fluconazole or caspofungin induced; transcription is regulated by Nrg1p, Mig1p, Tup1p, Gcn2p, Gcn4p, and alkaline regulated by Rim101p; fungal-specific [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 57471 60058 - orf19.1195 57471 60058 1 60058 57471 60009 57658 orf19.8786|IPF26128.1|IPF7154.2|Contig4-3055_0020|orf6.2848|CA1374|CaO19.1195|OCT1|MIP1|CaO19.8786 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 60817 63718 + orf19.1196 60817 63718 1 60817 63718 60917 63502 orf19.8787|IPF7158.2|IPF29542.1|Contig4-3055_0016|Contig4-3055_0017|Contig4-3055_0018|orf6.2849|CA1375|CaO19.1196|IPF7158 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 63439 64268 - orf19.1198 63439 64268 1 64268 63439 64239 63694 orf19.8789|IPF7159.2|IPF29549.1|Contig4-3055_0014|orf6.2851|orf6.2947|CA1376|CaO19.1198|IPF7159 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 64403 66265 - orf19.1199 64403 66265 1 66265 64403 66035 64485 NOP5 orf19.8790|IPF18691.2|IPF7161.1|NOP58|Contig4-3055_0011|Contig4-3055_0012|orf6.2852|orf6.2946|CA1438|CaO19.1199 Protein similar to S. cerevisiae Nop5p protein of small nucleolar ribonucleoprotein complex; transposon mutation affects filamentous growth; macrophage/pseudohyphal-induced; physically interacts with TAP-tagged Nop1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 66360 67556 - orf19.1200 66360 67556 1 67556 66360 67495 66500 orf19.8791|IPF26140.1|IPF7163.1|Contig4-3055_0009|orf6.2945|CA1437|CaO19.1200|CaO19.8791|IPF7163 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 67551 69156 + orf19.1201 67551 69156 1 67551 69156 67551 69041 orf19.8792|IPF26135.1|IPF7165.1|Contig4-3055_0008|orf6.2944|CA1436|CaO19.1201|DIA4|IPF7165 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr6 68994 70464 - orf19.1202 68994 70464 1 70464 68994 70422 69088 orf19.8793|IPF26137.1|IPF7166.2|Contig4-3055_0007|orf6.2943|CA1435|CaO19.1202|IPF7166 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 70590 73923 - orf19.1203 70590 73923 1 73923 70590 73882 70652 SRO77 orf19.8794|IPF26148.1|IPF12463.2|Contig4-3055_0006|orf6.2942|CA1434|CaO19.1203|CaO19.8794|SNI2 Predicted ORF in Assemblies 19, 20 and 21; filament induced; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 74123 74819 + orf19.1203.1 74123 74819 2 74123|74251 74164|74819 74162 74505 IPF26149.1|IPF12464.1|Contig4-3055_0003|orf6.2151|CA1433|IPF12464 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 74546 76226 - orf19.1204 74546 76226 1 76226 74546 76177 74639 orf19.8795|IPF26134.1|IPF12465.2|Contig4-3055_0002|orf6.2941|CA1432|CaO19.8795|APM3|CaO19.1204 Phosphorylated protein of unknown function, transcription is upregulated clinical isolates from HIV positive patients with oral candidiasis; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 76394 78902 - orf19.4215 76394 78902 1 78902 76394 78587 76710 FET34 orf19.11691|orf19.8797|orf6.5006|orf6.2939|IPF26138.1|IPF12467.2|IPF23068.1|IPF17039.1|FET5|FET34.3eoc|CA1431|CA2920|orf19.1206|FET35|FET5.5eoc Protein similar to multicopper ferroxidase; expression greater in low iron and reduced in a fluconazole-resistant isolate; downregulated by Sfu1p, Hog1p; alkaline upregulated by Rim101p; ciclopirox olamine induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 78972 79373 - orf19.4214 78972 79373 1 79373 78972 79373 78972 orf19.11690|IPF17037|IPF23070.1|IPF17037.2|orf6.5007|CA2921|CaO19.4214|CaO19.11690 [NOT TRANSCRIBED?] Protein not essential for viability [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 79836 82114 - orf19.4213 79836 82114 1 82114 79836 82105 80231 FET31 FET33|IPF17035.2|IPF11903.2|orf6.789|CA2922|CaO19.4213|orf6.5008 Predicted ORF in Assemblies 19, 20 and 21; flucytosine induced; caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 83190 86153 - orf19.4212 83190 86153 1 86153 83190 85591 83711 FET99 orf19.11689|orf6.5009|FET32|IPF11905.2|IPF17401.3|Contig4-2671_0004|Contig4-2671_0005|orf6.790|CA2923|CaO19.4212 Protein of multicopper oxidase family; similar to S. cerevisiae Fet3p; does not functionally complement S. cerevisiae fet3 mutant growth under low-iron conditions; iron-repressed transcription; regulated by Tup1p, Rim101p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 87061 89682 - orf19.4211 87061 89682 1 89682 87061 89365 87506 FET3 orf19.11687|FET33|IPF11908.2|IPF19406.2|Contig4-2671_0009|Contig4-2671_0010|orf6.176|orf6.5010|CA2924|CaO19.4211|FET31|CaO19.11687 Multicopper oxidase; required for growth under low-iron conditions; null mutant shows decreased prostaglandin E2 production; functional homolog of S. cerevisiae Fet3p; ketoconazole, caspofungin, amphotericin B repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 89882 90061 + ntar_970 89882 90061 1 89882 90061 89893 90027 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 92626 94243 + orf19.4210 92626 94243 1 92626 94243 92713 94104 orf19.11686|IPF23064.1|IPF7827.2|Contig4-2854_0022|orf6.5011|CA2925|CaO19.4210|CaO19.11686|IPF7827 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 94155 95353 - orf19.4209 94155 95353 1 95353 94155 95242 94247 orf19.11685|IPF23065.1|IPF7830.2|Contig4-2854_0019|orf6.5012|CA2926|UBA3|CaO19.11685|CaO19.4209 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 95609 97497 - orf19.4208 95609 97497 1 97497 95609 97421 95727 RAD52 orf19.11684|IPF23060.1|IPF7833.2|Contig4-2854_0016|orf6.5013|CA2927|CaO19.4208|CaO19.11684 Required for homologous DNA recombination, repair of UV- or MMS-damaged DNA, telomere length, UV-induced LOH; constitutive expression, MMS-induced; weakly complements S. cerevisiae rad52 mutant; slow growth, increased white-to-opaque switch [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 97673 98413 - orf19.4205.1 97673 98413 1 98413 97673 98367 98107 IPF23056.1|IPF7835.1|Contig4-2854_0013|CA2928|SME1 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 97694 98148 + ntar_971 97694 98148 1 97694 98148 97732 98046 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 98463 100504 + orf19.4206 98463 100504 1 98463 100504 98566 100410 orf19.11682|IPF23059.1|IPF7838.1|Contig4-2854_0012|orf6.5015|CA2929|CaO19.11682|MUS81|CaO19.4206|IPF7838 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 100558 101614 + orf19.4204 100558 101614 1 100558 101614 100601 101506 orf19.11680|IPF23066.1|IPF7840.1|Contig4-2854_0009|orf6.5017|CA2930|CaO19.4204|PET123|CaO19.11680|IPF7840 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 101805 104045 + orf19.4203 101805 104045 1 101805 104045 101853 103841 orf19.11679|IPF23058.1|IPF7841.2|Contig4-2854_0008|orf6.5018|CA2931|NDC1|CaO19.11679|CaO19.4203|IPF7841 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 103959 106183 - orf19.4201 103959 106183 1 106183 103959 105983 103992 NHX1 orf19.11677|IPF7842.1|IPF28496.1|Contig4-2854_0007|orf6.5020|CA2932|CaO19.4201|CaO19.11677 Protein similar to S. cerevisiae Nhx1p, which is an Na+/H+ exchanger required for intracellular sequestration of Na+ [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 107404 107763 + orf19.4200 107404 107763 1 107404 107763 107404 107763 orf19.11676|IPF23075.1|IPF28499.1|orf6.2735|orf6.5021|CaO19.4200 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 107781 109616 + orf19.4199 107781 109616 1 107781 109616 107927 109498 orf19.11675|IPF15071.3|IPF12346.2|Contig4-2426_0006|orf6.2736|orf6.5022|CA1300|CaO19.4199|SLY41 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 109535 110915 - orf19.4197 109535 110915 1 110915 109535 110646 109741 YHM2 orf19.11673|IPF23067.1|IPF12348.2|Contig4-2426_0005|orf6.2738|CA1301|CaO19.4197|CaO19.11673 Alkaline upregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 111222 111554 - orf19.4196 111222 111554 1 111554 111222 111554 111222 IPF18710.1|orf6.2739|CaO19.4196 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 112220 112900 + orf19.4195.1 112220 112900 2 112220|112432 112361|112900 112307 112829 FCA1 FCY1|IPF12349.1|IPF13513.1|Contig4-2373_0001|Contig4-2426_0003|CA1302|FCA1.3 Cytosine deaminase; enzyme of pyrimidine salvage; functional homolog of S. cerevisiae Fcy1p; mutation is associated with resistance to flucytosine (5-FC) in a clinical isolate; hyphal downregulated; gene has intron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 112954 113590 + orf19.4195 112954 113590 1 112954 113590 112970 113368 orf19.11672|IPF23072.1|IPF28497.1|Contig4-2373_0003|Contig4-2426_0002|orf6.2740|orf6.652|CaO19.4195 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 113082 114481 - orf19.4194 113082 114481 1 114481 113082 114469 113378 orf19.11671|IPF12351.3|IPF13511.2|Contig4-2373_0004|Contig4-2373_0005|Contig4-2426_0007|orf6.2741|orf6.651|CA1303|CaO19.4194|TFB4 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 114606 115636 - orf19.4193.1 114606 115636 2 115636|115165 115570|114606 115590 114731 RPS13 IPF23071.1|IPF13509.2|Contig4-2373_0006|CA1304|RPS13.3 Putative ribosomal protein; ORF predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 115702 116604 - orf19.4193 115702 116604 4 116604|116410|116245|115930 116475|116314|115993|115702 116477 115873 orf19.11670|IPF23074.1|IPF13508.2|Contig4-2373_0007|orf6.2742|CA1305|CaO19.11670|CaO19.4193|IPF13508.3f|IPF13508 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 116718 118926 + orf19.4192 116718 118926 2 116718|117014 116938|118926 116893 118596 CDC14 orf19.11669|IPF23063.1|IPF13507.2|Contig4-2373_0009|orf6.2743|CA1306|CDC14.3 Protein involved in exit from mitosis and morphogenesis; ortholog of S. cerevisiae Cdc14p, which is a dual-specificity phosphatase and cell-cycle regulator; suppresses S. cerevisiae cdc15-lyt1, dbf2-2, and (partially) tem1 mutant phenotypes [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 118594 119336 - orf19.4192.1 118594 119336 2 119336|119208 119285|118594 119287 118747 Predicted ORF in Assembly 20 and 21; gene has intron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 119401 121162 + orf19.3660 119401 121162 1 119401 121162 119503 121029 orf19.11144|IPF23638.1|IPF12270.3|orf6.3301|CA1685|CaO19.3660|CaO19.11144|IPF12270.3eoc|IPF12270|IPF12270.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 121022 122151 - orf19.3659 121022 122151 1 122151 121022 122019 121120 orf19.11143|IPF23639.1|IPF12272.1|Contig4-2704_0009|orf6.3302|CA1686|CaO19.11143|CaO19.3659|IPF12272 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 122314 124565 + orf19.3658 122314 124565 1 122314 124565 122527 124470 orf19.11142|IPF23630.1|IPF12275.2|Contig4-2704_0008|orf6.3303|CA1687|CaO19.11142|CaO19.3658|IPF12275 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 124455 126092 - orf19.3656 124455 126092 1 126092 124455 126008 124569 COX15 orf19.11140|IPF23635.1|IPF13028.2|Contig4-2704_0006|orf6.3305|CA1688|CaO19.3656|CaO19.11140 Transcription is regulated by Nrg1p and Tup1p; alkaline downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 126597 128513 + orf19.3655 126597 128513 1 126597 128513 126597 128513 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 128105 128311 - ntar_972 128105 128311 1 128311 128105 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 128414 128639 - ntar_973 128414 128639 1 128639 128414 128579 128418 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 129619 131926 + orf19.3653 129619 131926 1 129619 131926 129850 131802 FAT1 orf19.11137|IPF23631.1|IPF13033.1|Contig4-3041_0021|orf6.3308|CA1690|CaO19.3653|CaO19.11137 Predicted enzyme of sphingolipid biosynthesis; upregulated in biofilm [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 131889 133343 - orf19.3651 131889 133343 1 133343 131889 133290 132037 PGK1 orf19.11135|PGK|IPF23636.1|IPF17009.2|Contig4-3041_0020|orf6.3310|CA1691|CaO19.11135|CaO19.3651 Phosphoglycerate kinase; enzyme of glycolysis; localizes to cell wall and to cytoplasm; antigenic during murine or human systemic infection; biofilm, Hog1p, GCN-induced; downregulated upon phagocytosis; possible N-glycosylation at N349 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 134058 135213 + orf19.3649 134058 135213 1 134058 135213 134314 135168 orf19.11133|IPF9690.1|IPF17003.3|Contig4-3041_0019|orf6.3312|orf6.664|CA0147|CaO19.3649|IPF9690 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 135105 137098 - orf19.3648 135105 137098 2 137098|136848 136934|135105 137049 135201 orf19.11132|IPF9689.3|IPF28695.1|Contig4-3041_0018|orf6.3029|orf6.663|CA0146|IPF9689|IPF9689.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 137305 140802 + orf19.3647 137305 140802 1 137305 140802 137397 140720 orf19.11131|IPF23650.1|IPF9686.1|Contig4-3041_0015|Contig4-3041_0016|orf6.3030|CA1495|SEC8|CaO19.11131|CaO19.3647|IPF9686 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 140747 141846 - orf19.3646 140747 141846 1 141846 140747 141631 140876 CTR1 orf19.11130|orf6.3031|IPF23640.1|IPF9685.1|Contig4-3041_0013|CA1496|CaO19.11130|CaO19.3646 Copper transporter; probably multimeric; transcribed if copper limited; induced by Mac1p, macrophage interaction, alkaline pH via Rim101p; 17-beta-estradiol downregulated; complements S. cerevisiae ctr1 ctr3 copper transport mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 142161 144795 - orf19.3644 142161 144795 1 144795 142161 144532 142349 orf19.11128|IPF12378.2|IPF9683.2|Contig4-3041_0010|orf6.2642|orf6.3033|CA1497|CaO19.3644|IPF9683 Predicted ORF in Assemblies 19, 20 and 21; greater mRNA abundance observed in a cyr1 homozygous null mutant than in wild type [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr6 149427 150599 - orf19.3643 149427 150599 1 150599 149427 150599 149427 orf19.11126|IPF13346.1|IPF12371.2|Contig4-1804_0004|Contig4-3041_0003|orf6.2641|orf6.3034|CA1498|CaO19.3643|IPF12371|IPF12371.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 156922 159809 + orf19.3642 156922 159809 2 156922|158242 157220|159809 158331 159587 SUN41 orf19.11124|orf6.2071|IPF23637.1|IPF14577.2|Contig4-2119_0002|CA0883|SUN4|CaO19.3642|CaO19.11124 Putative cell wall glycosidase involved in biofilm formation; required for cell separation; hyphal induced; caspofungin repressed; Efg1p, Cph1p regulated; O-glycosylation, potential Kex2p substrate; 9 5' E-boxes; 5'-UTR intron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr6 159777 162844 - orf19.84 159777 162844 3 162844|161469|161336 161566|161420|159777 161777 159898 CAN3 orf19.11123|orf19.7729|IPF23634.1|IPF19550.1|IPF27172.1|IPF19551.1|IPF14582.1|Contig4-2119_0003|orf6.115|orf6.2072|orf19.3641 Predicted ORF in Assemblies 19, 20 and 21; expression is regulated upon white-opaque switching [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 164973 165749 + orf19.85 164973 165749 1 164973 165749 165076 165567 GPX2 orf19.7730|orf6.1558|GPX1|IPF16333.2|IPF13205.1|GPX3|Contig4-2178_0002|CA0558|GPS1|CaO19.85|CaO19.7730 Similar to glutathione peroxidase; expression greater in high iron; alkaline upregulated by Rim101p; transcriptionally induced by alpha factor or interaction with macrophage; regulated by Efg1p; caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 167115 167767 + orf19.86 167115 167767 1 167115 167767 167189 167674 orf19.7731|GPX1|IPF27177.1|IPF13207.2|Contig4-2178_0004|orf6.1559|CA0559|CaO19.86|GPS2|CaO19.7731|HYR1 Protein described as glutathione peroxidase; macrophage-downregulated gene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 168181 168809 + ntar_974 168181 168809 1 168181 168809 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 168766 169219 - ntar_975 168766 169219 1 169219 168766 169219 168938 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 169068 169956 + orf19.87 169068 169956 1 169068 169956 169171 169860 GPX1 orf19.7732|IPF27176.1|IPF13211.1|GPX3|Contig4-1857_0003|Contig4-1857_0004|orf6.1560|orf6.3698|CA0560|GPS3|CaO19.87 Predicted ORF in Assemblies 19, 20 and 21; peroxide-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 169349 169519 - ntar_976 169349 169519 1 169519 169349 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 169952 171427 - orf19.88 169952 171427 1 171427 169952 171374 170172 ILV5 orf19.7733|IPF9595.2|IPF19137.2|Contig4-2691_0001|orf6.3699|orf6.810|CA1983|CaO19.88 Protein described as ketol-acid reductoisomerase; antigenic during human or murine infection; regulated by Gcn4p; amino acid starvation (3-aminotriazole) induced; biofilm induced; macrophage-downregulated protein; no human or murine homolog [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 172074 173862 + orf19.89 172074 173862 1 172074 173862 172306 173448 orf19.7735|IPF27170.1|IPF9594.2|Contig4-2691_0003|orf6.3701|orf6.811|CA0191|PEX7|CaO19.89 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 174517 176993 + orf19.90 174517 176993 1 174517 176993 174667 176931 orf19.7736|IPF9592.2|IPF19136.2|Contig4-2691_0004|Contig4-2691_0007|orf6.3702|orf6.812|CA1984|CaO19.90|IPF9592 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 176730 177982 - orf19.91 176730 177982 1 177982 176730 177896 176997 orf19.7737|IPF27171.1|IPF9591.2|Contig4-2691_0008|orf6.3703|CA1985|CaO19.7737|CaO19.91|IPF9591 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 178321 181184 - orf19.92 178321 181184 1 181184 178321 181089 178399 orf19.7738|IPF27156.1|IPF14899.2|Contig4-2691_0009|orf6.3704|CA1986|CaO19.92|CaO19.7738|IPF14899 Predicted ORF in Assemblies 19, 20 and 21; increased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 181478 181865 + ntar_977 181478 181865 1 181478 181865 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 182676 183336 + orf19.93 182676 183336 1 182676 183336 182745 183200 orf19.7739|IPF14895.1|IPF17607.2|Contig4-2306_0003|orf6.159|orf6.3705|CA1987|CaO19.93|IPF14895 Predicted ORF in Assemblies 19, 20 and 21; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 183242 184220 - orf19.94 183242 184220 1 184220 183242 184139 183405 orf19.7740|IPF17606.2|IPF19749.1|orf6.3706|CA1988|CaO19.94|CaO19.7740|IPF19749 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 184665 185809 - orf19.95 184665 185809 1 185809 184665 185701 184811 orf19.7741|IPF27173.1|IPF16596.2|Contig4-2327_0006|orf6.3707|CA1989|CaO19.7741|CaO19.95|IPF16596 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 186474 189207 - orf19.96 186474 189207 1 189207 186474 188928 186586 TOP1 orf19.7742|IPF17557.3|IPF29943.1|Contig4-2327_0003|Contig4-2327_0004|orf6.2499|orf6.3708|CA1990|CaO19.96|IPF17557.2 DNA topoisomerase I; required for wild-type growth and for wild-type mouse virulence; sensitive to camptothecin; induced upon adherence to polystyrene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 189393 189528 - ntar_978 189393 189528 1 189528 189393 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 191035 192887 + orf19.97 191035 192887 1 191035 192887 191106 192821 CAN1 orf19.7744|IPF16927.2|IPF10466.2|Contig4-2197_0003|orf6.2500|orf6.388|orf6.389|CAN2|CaO19.97|CA1148 Amino acid permease, transports basic amino acids; complements lysine transport mutation; contains 10 predicted transmembrane regions and 3 predicted N-glycosylation sites; transcriptionally induced upon phagocytosis by macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 192772 194190 - orf19.99 192772 194190 1 194190 192772 194149 193016 HAL21 orf19.7746|orf6.2502|IPF16926.2|IPF10464.2|Contig4-1664_0002|Contig4-2197_0005|MET222|CA1149|CaO19.99|MET223 Putative phosphoadenosine-5'-phosphate (PAP) or 3'-phosphoadenosine 5'-phosphosulfate (PAPS) phosphatase; possible role in sulfur recycling; biofilm induced; similar to S. cerevisiae Met22p; predicted Kex2p substrate; fungal-specific [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=G scenario_last_exon=G] Ca21chr6 194192 195524 - orf19.100 194192 195524 1 195524 194192 195350 194298 orf19.7747|IPF10462.3|IPF29954.1|Contig4-2197_0007|orf6.2503|orf6.490|CA0093|CaO19.100|IPF29954|IPF19980.repeat2|IPF10462.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 195884 197087 + orf19.101 195884 197087 1 195884 197087 195973 197013 RIM9 orf19.7748|IPF20039.1|IPF10461.2|Contig4-1178_0001|orf6.2504|orf6.491|CA1150|CaO19.101 Protein required for alkaline pH response via the RIM101 signaling pathway; ortholog of S. cerevisiae RIM9 and A. nidulans palI [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 196928 198373 - orf19.102 196928 198373 1 198373 196928 198335 197055 orf19.7749|IPF17548.2|IPF10459.1|Contig4-1178_0003|orf6.2505|orf6.492|CA1151|CaO19.102|IPF10459 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr6 198432 199112 + orf19.103 198432 199112 1 198432 199112 198702 199112 KAR5 orf19.7750|IPF10457.3|Contig4-2013_0002|orf6.2506|CA1152|CaO19.103|IPF10457|CA1195|orf6.2573|IPF17213.2|IPF10457.2 Protein of unknown function; induced by alpha factor [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr6 199311 200183 + orf19.104 199311 200183 1 199311 200183 199311 200183 IPF17213.3|IPF10455.3|Contig4-2013_0005|orf6.2507|CA1153|CaO19.104|IPF10455|IPF10455.2 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction); transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr6 200447 201825 + orf19.105 200447 201825 1 200447 201825 200468 201649 HAL22 orf19.7752|IPF10454.1|Contig4-2013_0008|orf6.2508|orf6.2571|orf6.390|MET222|CA1154|MET22|CaO19.105|MET221|CA1194|IPF17216.2 Putative phosphoadenosine-5'-phosphate (PAP) or 3'-phosphoadenosine 5'-phosphosulfate (PAPS) phosphatase; possible role in sulfur recycling; induced upon biofilm formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr6 201656 204245 - orf19.107 201656 204245 1 204245 201656 204200 201705 orf19.7754|IPF27157.1|IPF10452.3|Contig4-2013_0010|Contig4-2501_0010|orf6.2510|orf6.2569|CA1155|DHR2|CaO19.107|JA2|IPF10452.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 204390 206094 + orf19.109 204390 206094 1 204390 206094 204422 205927 orf19.7756|IPF11923.1|IPF10449.3|Contig4-2501_0009|orf6.2567|CA1193|CaO19.7756|MSY1|CaO19.109 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 205910 207890 - orf19.111 205910 207890 1 207890 205910 207755 206049 CAN2 orf19.7758|IPF27165.1|IPF11927.1|Contig4-2501_0008|orf6.2565|CAN1|CaO19.111|CaO19.7758|CA1191|CA1192|IPF11926|IPF11926.1 Putative amino acid permease; transcription is regulated by Nrg1p and Tup1p; caspofungin induced; flucytosine induced; shows colony morphology-related gene regulation by Ssn6p; ; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 209464 210363 - orf19.113 209464 210363 1 210363 209464 210363 209464 CIP1 orf19.7761|IPF11929.2|IPF14967.2|COR33|Contig4-2149_0001|Contig4-2501_0003|orf6.1181|orf6.2562|CA1190|CaO19.113 Protein with slight similarity to plant isoflavone reductase; transcription induced by cadmium (specifically, not by other heavy metals or heat shock), yeast-hyphal switch, oxidative stress (via Cap1p), or macrophage interaction [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr6 211668 212882 - orf19.114 211668 212882 1 212882 211668 212844 211849 orf19.7762|IPF19622.2|IPF19689.1|Contig4-2149_0004|orf6.1182|CA6312|CaO19.114|IPF19622.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr6 212918 213981 - orf19.115 212918 213981 2 213981|213865 213933|212918 213969 213048 IPF19623.1|Contig4-2149_0006|Contig4-2149_0007|orf6.1183|CA0484|CaO19.115|IPF19622.5f|IPF19622|orf6.1446|IPF19622.1 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 214457 216329 + orf19.117 214457 216329 1 214457 216329 214611 216203 orf19.7764|IPF19868.1|IPF14761.2|Contig4-3075_0021|orf6.1185|orf6.1444|CA0483|CaO19.117|SEC9 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 217185 217808 - ntar_979 217185 217808 1 217808 217185 217692 217531 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 218201 219679 + orf19.118 218201 219679 1 218201 219679 218253 219563 FAD2 orf19.7765|IPF14763.2|IPF29951.1|Contig4-2244_0003|orf6.1443|CA0482|CaO19.7765|ODE1|CaO19.118|IPF14763 Delta-12 fatty acid desaturase, involved in production of linoleic acid, which is a major component of membranes [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 219621 220684 - orf19.119 219621 220684 1 220684 219621 220608 219811 orf19.7766|IPF14764.1|IPF29956.1|Contig4-2244_0002|orf6.1442|CA0481|STE14.3f|STE14 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 220692 221714 + orf19.120 220692 221714 1 220692 221714 220895 221713 orf19.7767|Contig4-2238_0009|orf6.1441|orf6.405|CA0067|STE142|CaO19.120|IPF13904|IPF13904.2 Predicted ORF from Assembly 19; removed from Assembly 20; subsequently reinstated in Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=G scenario_last_exon=G] Ca21chr6 221541 222525 - orf19.121 221541 222525 1 222525 221541 222243 221695 ARC18 orf19.7768|IPF27178.1|IPF13905.2|Contig4-2238_0008|orf6.406|CA0068|CaO19.121|CaO19.7768 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to cytochalasin D [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 223361 226635 + orf19.122 223361 226635 1 223361 226635 224232 226331 CDC20 orf19.7769|IPF13908.2|IPF19430.2|Contig4-2238_0005|orf6.139|orf6.2609|CA1218|CaO19.122 Protein similar to S. cerevisiae Cdc20p; induced under Cdc5p depletion; member of conserved Mcm1p regulon; mRNA expression peaks at cell-cycle G2/M phase; mRNA binds to She3p and is localized to buds of yeast-form cells and hyphal tips [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr6 226861 227916 + orf19.123 226861 227916 1 226861 227916 226997 227629 RCN1 orf19.7770|IPF13909.1|IPF7047.3|Contig4-2238_0001|Contig4-2900_0028|orf6.138|orf6.2608|CA1217|CaO19.123|IPF13909 Protein involved in calcineurin-dependent signaling that controls stress response and virulence; inhibits calcineurin function [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 228073 229450 + orf19.124 228073 229450 1 228073 229450 228119 229216 CIC1 orf19.7771|IPF27169.1|IPF7046.2|Contig4-2900_0027|orf6.137|orf6.2607|CA0020|CaO19.124|IPF7046 Predicted ORF in Assemblies 19, 20 and 21; transcription is upregulated in both intermediate and mature biofilms [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 229315 230833 - orf19.125 229315 230833 1 230833 229315 230692 229469 EBP1 orf19.7772|Contig4-2900_0026|IPF7044.2|IPF29953.1|orf6.2606|CA1216|CaO19.125 NADPH oxidoreductase; interacts with phenolic substrates, such as 17beta-estradiol; possible role in response to estrogen; induced by oxidative and weak acid stress, nitric oxide, benomyl; activated by Cap1p, Mnl1p; no mammalian homolog [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 232080 236909 - orf19.130 232080 236909 1 236909 232080 236909 232296 orf19.7773|orf19.7775|orf19.7776|IPF7041.2|IPF27168.1|IPF7035.2|IPF19493.2|IPF29955.1|IPF7038.2|IPF29948.1|Contig4-2900_0020|Contig4-2900_0021|Contig4-2900_0023|orf6.10|orf6.2603|orf6.2602|orf6.2605|CA1215|CA1214|CA1213|orf19.126|orf19.127|orf19.129|VPS15.5f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr6 237041 237786 + orf19.131 237041 237786 1 237041 237786 237112 237786 orf19.7777|IPF7033.2|IPF29957.1|Contig4-2900_0017|orf6.2601|CA1212|CaO19.131|BRR1|IPF7033 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 237906 238448 + orf19.131.2 237906 238448 2 237906|238006 237940|238448 237906 238318 IPF7031.2|IPF29965.1|Contig4-2900_0015|CA1211|IPF7031.3f|IPF7031.3 ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 238421 240372 - orf19.132 238421 240372 1 240372 238421 240202 238421 orf19.7778|IPF7030.3|IPF29947.1|Contig4-2900_0013|orf6.2600|orf6.3482|CA1210|SIF2|CaO19.132|IPF7030|IPF7030.2 Putative ortholog of S. cerevisiae SIF2; has a LisH motif; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr6 242064 242387 + orf19.133 242064 242387 1 242064 242387 242064 242387 IPF29964.1|Contig4-2900_0011|orf6.3481|CaO19.133 Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide in yhb1 mutant [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 244274 244684 + orf19.134 244274 244684 1 244274 244684 244274 244684 IPF7023.2|Contig4-2900_0005|orf6.3480|CA1818|CaO19.134|IPF7023.3f|IPF7023.3 Predicted ORF in Assemblies 19, 20 and 21; ciclopirox olamine induced [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 245415 248025 + orf19.135 245415 248025 1 245415 248025 245503 247878 orf19.7779|IPF18738.2|IPF7021.2|Contig4-2900_0003|orf6.2599|orf6.3479|CA1817|CaO19.135|IPF7021 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 247851 250254 - orf19.136 247851 250254 1 250254 247851 250103 248010 orf19.7780|IPF16599.3|IPF7020.2|Contig4-2900_0029|orf6.3478|orf6.459|CA1816|QDR3|CaO19.136|IPF7020 Predicted membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 251503 253046 + orf19.137 251503 253046 1 251503 253046 251684 252925 orf19.7781|IPF16598.2|IPF29952.1|orf6.3477|orf6.458|CA0086|CaO19.137|IPF16598 Predicted ORF in Assemblies 19, 20 and 21; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 253239 254036 + orf19.138 253239 254036 1 253239 254036 253239 254036 FIG1 orf19.7782|orf6.3476|IPF27175.1|IPF18606.1|CA1815|CaO19.7782|CaO19.138|IPF18606 Probable ortholog of S. cerevisiae Fig1p, which is an integral membrane protein required for mating; role in thigmotropism; transcription is opaque-specific, a-specific, and activated by Cph1p or alpha pheromone [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 254445 266092 + orf19.139 254445 266092 1 254445 266092 254562 266027 TRA1 orf19.7783|orf19.10955|IPF27181.1|IPF14787.2|IPF23848.1|IPF5342.2|orf6.3475|orf6.2789|CA1814|CA1335|orf19.3451|TRA1.5eoc Subunit of the NuA4 histone acetyltransferase complex [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr6 266085 266917 - orf19.3450.1 266085 266917 2 266917|266594 266675|266085 266917 266178 orf19.10954|IPF23864.1|IPF5338.2|orf6.2790|orf19.3450|CA6209|IPF5336 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 267288 268066 - orf19.3449.2 267288 268066 2 268066|267689 267780|267288 267995 267288 IPF23870.1|IPF5335.1|orf19.3449.1|CA1337|IPF5334|CA1336|IPF5334.exon2 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 268131 270459 + orf19.3449 268131 270459 1 268131 270459 268193 270313 orf19.10953|IPF5333.2|IPF18267.2|Contig4-2082_0004|orf6.2791|orf6.6456|CA1338|CaO19.3449|IPF5333 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 269503 270171 - ntar_980 269503 270171 1 270171 269503 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 270359 270829 - ntar_981 270359 270829 1 270829 270359 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 271929 272947 + orf19.3448 271929 272947 1 271929 272947 272389 272730 orf19.10952|IPF5330.2|IPF28770.1|orf6.2792|orf6.6457|CA1339|CaO19.3448|IPF5330 Predicted ORF in Assemblies 19, 20 and 21; ketoconazole-repressed; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 273226 273809 - ntar_982 273226 273809 1 273809 273226 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 273437 275829 + orf19.3447 273437 275829 1 273437 275829 274110 275555 orf19.10951|IPF18703.2|IPF5328.2|Contig4-2814_0003|orf6.2793|orf6.6458|CA4017|CaO19.3447|PBN1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 274773 274976 - ntar_983 274773 274976 1 274976 274773 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 275346 276377 - orf19.3446 275346 276377 1 276377 275346 276219 275605 orf19.10950|IPF23844.1|IPF5327.2|Contig4-2814_0004|orf6.6459|CA4018|MOG1|CaO19.3446|CaO19.10950 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 276344 277826 + orf19.3445 276344 277826 1 276344 277826 276568 277755 HOC1 orf19.10949|IPF23835.1|IPF5326.2|Contig4-2814_0005|orf6.6460|YJR75|CA4019|CaO19.10949|CaO19.3445 Protein with similarity to mannosyltransferases; similar to S. cerevisiae Hoc1p and C. albicans Och1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 277850 278171 - ntar_984 277850 278171 1 278171 277850 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 278862 280995 + orf19.3444 278862 280995 1 278862 280995 278862 280892 orf19.10948|IPF23814.1|IPF5324.2|Contig4-2814_0009|orf6.6461|CA4020|CaO19.3444|SGE13|CaO19.10948|IPF5324 Predicted membrane transporter, member of the drug:proton antiporter (14 spanner) (DHA2) family, major facilitator superfamily (MFS) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr6 279401 279829 - ntar_985 279401 279829 1 279829 279401 279667 279401 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 280948 282499 - orf19.3443 280948 282499 1 282499 280948 282365 281154 OYE2 orf19.10947|IPF23834.1|IPF5323.2|Contig4-2814_0011|orf6.6462|CaO19.10947|OYE22|CaO19.3443 Putative NAPDH dehydrogenase; fungal-specific (no human or murine homolog); induced by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 282749 284019 - orf19.3442 282749 284019 1 284019 282749 284006 282765 orf19.10946|IPF23833.1|IPF5322.2|Contig4-2814_0014|orf6.6463|CA4021|OYE23|CaO19.10946|CaO19.3442|EBP2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 284236 285876 + ntar_986 284236 285876 1 284236 285876 284888 285106 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 284716 286021 - orf19.3441 284716 286021 1 286021 284716 285703 284912 FRP6 orf19.10945|IPF23842.1|IPF5321.1|Contig4-2814_0016|orf6.6464|CA4022|CaO19.10945|AFF10|CaO19.3441 Transcription is regulated by Nrg1p and Tup1p; regulated by Ssn6p; upregulated in the presence of human neutrophils [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 286466 287230 + ntar_987 286466 287230 1 286466 287230 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 287518 288351 - orf19.3440 287518 288351 1 288351 287518 288351 287518 FRP5 orf19.10944|FUN34|IPF23843.1|IPF7185.2|Contig4-2644_0005|orf6.6465|CA4023|CaO19.10944|AFF11|CaO19.3440 Predicted ORF in Assemblies 19, 20 and 21; flucytosine repressed [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 289373 290574 - orf19.3439 289373 290574 1 290574 289373 290450 289497 orf19.10943|IPF23841.1|IPF7182.2|Contig4-2644_0006|orf6.6466|CA4024|CaO19.10943|CaO19.3439|IPF7182 Predicted ORF in Assemblies 19, 20 and 21; greater mRNA abundance observed in a cyr1 homozygous null mutant than in wild type [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 292700 294055 - orf19.3438 292700 294055 1 294055 292700 293962 292808 orf19.10942|IPF23837.1|IPF7178.2|Contig4-2644_0011|orf6.6467|CA4025|CaO19.10942|SCJ1|CaO19.3438 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 294615 296343 + orf19.3437 294615 296343 1 294615 296343 294697 296325 orf19.10941|IPF23824.1|IPF7175.2|orf6.6468|CA4026|CaO19.10941|CaO19.3437|IPF7175 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 296934 297544 + orf19.3436 296934 297544 1 296934 297544 296984 297529 orf19.10940|IPF23850.1|IPF7174.2|Contig4-2411_0003|orf6.6469|CA4027|CaO19.10940|CaO19.3436|IPF7174 Predicted ORF in Assemblies 19, 20 and 21; macrophage-induced gene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 297593 298197 - orf19.3435 297593 298197 1 298197 297593 298115 297672 orf19.10939|IPF23851.1|IPF7173.2|Contig4-2411_0004|orf6.6470|CA4028|CaO19.10939|CaO19.3435|IPF7171.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 298270 301239 - orf19.3434 298270 301239 1 301239 298270 301239 298270 orf19.10938|IPF23803.1|IPF7171.2|Contig4-2411_0005|orf6.6471|CA4029|CaO19.10938|CaO19.3434|IPF7171.5f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 304836 306056 + orf19.3433 304836 306056 1 304836 306056 304836 306056 OYE23 orf19.10937|IPF19549.2|IPF19548.1|orf6.6472|orf6.92|OYE21|EBP4|CA4030|CaO19.3433 Putative NAPDH dehydrogenase; induced by nitric oxide, benomyl; oxidative stress-induced via Cap1p; fungal-specific (no human or murine homolog) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 306758 308398 + orf19.3432 306758 308398 1 306758 308398 306758 308398 orf19.10936|IPF23823.1|IPF11077.2|Contig4-2589_0012|orf6.6473|CA4031|CaO19.10936|CaO19.3432|IPF11077 Predicted membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS); induced by nitric oxide [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 307090 307247 - ntar_988 307090 307247 1 307247 307090 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 309368 310568 - ntar_989 309368 310568 1 310568 309368 310071 309892 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 312622 313523 + ntar_990 312622 313523 1 312622 313523 312823 312954 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 313242 317908 - orf19.3431 313242 317908 1 317908 313242 317775 314089 orf19.10935|IPF23872.1|IPF19795.1|Contig4-2589_0001|Contig4-2589_0002|orf6.6474|CA4033|MIP1|CaO19.10935|CaO19.3431|IPF19795 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr6 318813 319241 - ntar_991 318813 319241 1 319241 318813 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 318817 319219 + ntar_992 318817 319219 1 318817 319219 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 319498 321282 + orf19.3430 319498 321282 1 319498 321282 319769 320803 orf19.10934|IPF23839.1|IPF7385.2|Contig4-1688_0002|orf6.6095|CA3748|CaO19.3430|CaO19.10934|IPF7385|BUD21 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction); physically interacts with TAP-tagged Nop1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 321375 324664 - orf19.3429 321375 324664 1 324664 321375 324463 321539 FGR47 orf19.10933|IPF23804.1|IPF7389.2|Contig4-1688_0001|orf6.6096|CA3749|CaO19.10933|CaO19.3429|IPF7389 Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr6 327541 327732 - ntar_993 327541 327732 1 327732 327541 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 328011 330163 + orf19.3428 328011 330163 1 328011 330163 328521 330002 orf19.10932|IPF23827.1|IPF7377.1|Contig4-2308_0006|orf6.6097|CA3750|CaO19.3428|CaO19.10932|IPF7377 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 330186 330536 + orf19.3427 330186 330536 1 330186 330536 330186 330536 orf19.10931|IPF23857.1|IPF7378.2|Contig4-2308_0004|Contig4-2308_0005|Contig4-2520_0001|Contig4-2520_0003|orf6.6098|CA3751|CaO19.10931|CaO19.3427|IPF7378 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 330558 332726 + orf19.3426 330558 332726 2 330558|331989 331271|332726 331257 332450 ANB1 orf19.10930|IPF23859.1|IPF20144.1|Contig4-2520_0008|orf6.6099|CA3752|TIF51|TIF51.3f|TIF51.3 Putative translation initiation factor; decreased expression in hyphae compared to yeast-form cells; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 330811 331100 - ntar_994 330811 331100 1 331100 330811 331050 330874 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 334641 336782 + orf19.3425 334641 336782 1 334641 336782 334921 336720 orf19.10929|IPF23817.1|IPF14743.2|Contig4-2520_0014|Contig4-2520_0015|Contig4-2520_0016|orf6.6100|CA3753|CaO19.10929|CaO19.3425|IPF14743 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 337055 339092 + orf19.3423 337055 339092 1 337055 339092 337289 338656 TIF3 orf19.10927|IPF23831.1|IPF16643.2|Contig4-2520_0017|orf6.6102|CA3754|CaO19.3423|CaO19.10927 Putative translation initiation factor; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 339486 340342 + orf19.3421.1 339486 340342 2 339486|339793 339714|340342 339657 340241 IPF23856.1|IPF17743.2|CA3755|IPF17743 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 340217 348064 - orf19.3422 340217 348064 1 348064 340217 348064 340358 FMP27 orf19.10926|IPF23847.1|IPF8884.2|Contig4-2903_0002|orf6.6103|CA3756|CaO19.10926|CaO19.3422|IPF8884 Putative protein of unknown function; mRNA binds She3p; fungal-specific (no human or murine homolog); predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr6 348496 348879 - orf19.3420 348496 348879 1 348879 348496 348879 348496 orf19.10924|IPF23862.1|IPF28763.1|Contig4-2903_0003|orf6.6105|CaO19.10924|CaO19.3420 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21; decreased expression in hyphae compared to yeast-form cells [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 350491 352718 + orf19.3419 350491 352718 1 350491 352718 350706 352598 MAE1 orf19.10923|IPF23815.1|IPF8888.2|Contig4-2903_0008|orf6.6106|CA3757|CaO19.10923|CaO19.3419 Malic enzyme, mitochondrial; transcription regulated by Mig1p and Tup1p; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 352648 353854 - orf19.3418 352648 353854 1 353854 352648 353854 352769 orf19.10922|IPF8889.2|IPF14736.3|Contig4-2903_0009|orf6.2731|orf6.6107|CA3758|CaO19.3418|AFP98|IPF8889 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr6 354206 356498 + orf19.3417 354206 356498 1 354206 356498 354214 356418 ACF2 orf19.10921|IPF23811.1|IPF14734.2|Contig4-2903_0011|Contig4-2923_0026|orf6.2732|orf6.6108|ENG2|CA1297|CaO19.3417 Putative endo-1,3-beta-glucanase; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr6 354963 356498 - ntar_995 354963 356498 1 356498 354963 356498 356190 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 356847 358153 + orf19.3415.1 356847 358153 2 356847|357455 357012|358153 357012 357849 RPL32 IPF23866.1|IPF12449.2|Contig4-2923_0003|CA1298 Predicted ribosomal protein [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 358023 360785 - orf19.3415 358023 360785 1 360785 358023 360612 358174 PTK2 orf19.10918|IPF23808.1|IPF12448.2|Contig4-2923_0004|Contig4-2923_0005|Contig4-2923_0006|orf6.2734|orf6.6110|CA1299|CaO19.3415 Putative protein kinase of polyamine import; mutation confers hypersensitivity to high concentrations of tunicamycin; upregulated in biofilm [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 362426 362660 + ntar_996 362426 362660 1 362426 362660 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 363878 365166 - orf19.3414 363878 365166 1 365166 363878 365076 364264 SUR7 orf19.10917|IPF12442.1|IPF12038.2|Contig4-2923_0010|orf6.360|CA0055|CaO19.10917|CaO19.3414|IPF12442 Protein required for wild-type cell wall, plasma membrane, cytoskeletal organization, endocytosis; localizes to eisosome subdomains of plasma membrane; four transmembrane motifs; mutant shows ectopic, chitin-rich cell wall [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 366036 366344 + orf19.3413 366036 366344 1 366036 366344 366036 366344 FGR37 orf19.10916|IPF23877.1|IPF12034.2|Contig4-2923_0016|orf6.2102|CA0902|CaO19.10916|CaO19.3413|IPF12034 Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 366336 368450 - orf19.3412 366336 368450 1 368450 366336 368297 366504 ATG15 orf19.10915|IPF23816.1|IPF12033.2|Contig4-2923_0017|orf6.2101|CA0901|CaO19.3412|CaO19.10915|IPF12033 Putative lipase; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 368614 369689 - orf19.3411 368614 369689 1 369689 368614 369515 368628 orf19.10914|IPF9910.1|IPF12031.1|Contig4-2923_0018|orf6.2100|orf6.4320|CA0900|CaO19.3411|IPF12031 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 369819 372484 + orf19.3409 369819 372484 1 369819 372484 369918 372443 SEC12 orf19.10912|orf6.2098|IPF9907.2|IPF12029.2|Contig4-2923_0022|orf6.4323|CA2425|CaO19.3409|IPF9907 Protein described as a guanyl-nucleotide exchange factor; transcriptionally regulated by iron; expression greater in high iron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 372764 374140 + orf19.3407 372764 374140 1 372764 374140 372783 373919 orf19.10910|IPF23836.1|IPF9901.1|Contig4-2923_0023|orf6.4324|CA2426|CaO19.3407|RAD18|CaO19.10910|IPF9901 Putative transcription factor with zinc finger DNA-binding motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 374012 375744 - orf19.3406 374012 375744 1 375744 374012 375610 374207 orf19.10909|IPF23830.1|IPF9898.2|Contig4-2923_0025|orf6.4325|CA2427|CaO19.3406|CaO19.10909|IPF9898 Predicted ORF in Assemblies 19, 20 and 21; member of conserved Mcm1p regulon [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 376278 378236 - orf19.3405 376278 378236 2 378236|378087 378148|376278 378225 376633 ZCF18|orf19.10908|IPF23829.1|IPF9894.2|Contig4-2230_0002|orf6.4326|CA2428|IPF9894|IPF9894.3 Putative transcription factor with zinc finger DNA-binding motif; heterozygous null mutant displays sensitivity to virgineone; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 378751 378823 + ta(ugc)1 378751 378823 1 378751 378823 tA(UGC)1.2 tRNA-Ala predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 379014 380495 + orf19.3404 379014 380495 1 379014 380495 379014 380495 orf19.10907|IPF23828.1|IPF9890.1|IPF9890|Contig4-2230_0003|Contig4-2230_0005|orf6.4327|CA2429|CaO19.10907|CaO19.3404 Decreased transcription is observed upon fluphenazine treatment [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 379547 379904 - ntar_997 379547 379904 1 379904 379547 379897 379547 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 380326 381793 - orf19.3402 380326 381793 2 381793|381663 381731|380326 381748 380539 FPG1 orf19.10905|IPF23838.1|IPF12950.2|Contig4-2230_0006|Contig4-2399_0005|orf6.4329|CA2430|FDG1|CaO19.3402|CaO19.10905|IPF12950 Formamidopyrimidine DNA glycosylase, involved in repair of gamma-irradiated DNA [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr6 381859 382718 + orf19.3401 381859 382718 1 381859 382718 381908 382564 CTA1 orf19.10904|IPF23849.1|IPF12951.2|Contig4-2399_0004|orf6.4330|CA2431|MOS10|VPS60|CaO19.10904|CaO19.3401|IPF12951 Protein similar to S. cerevisiae Mos10p, which affects S. cerevisiae filamentous growth; activates transcription in 1-hybrid assay in S. cerevisiae; protein levels increase under weak acid stress; nonessential [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 382463 383593 - orf19.3400 382463 383593 1 383593 382463 383593 382610 COQ3 orf19.10903|IPF23840.1|IPF12953.1|Contig4-2399_0003|orf6.4331|CA2432|CaO19.3400|CaO19.10903 Protein described as having role in coenzyme Q biosynthesis; transcriptionally induced by interaction with macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr6 383688 386164 + orf19.3399 383688 386164 1 383688 386164 383745 386039 orf19.10902|IPF23810.1|IPF12959.2|Contig4-2399_0001|Contig4-2516_0010|orf6.4332|CA2433|VPS72|CaO19.10902|CaO19.3399|IPF12959 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 385985 386706 - orf19.3396 385985 386706 2 386706|386544 386628|385985 386653 386112 HCH1 orf19.10899|IPF23860.1|IPF9484.2|Contig4-2516_0001|orf6.4335|CA2434|IPF9484 Protein not essential for viability; regulated by Gcn4p; induced in response to amino acid starvation (3-aminotriazole treatment); similar to S. cerevisiae Hch1p, which is a regulator of heat shock protein Hsp90p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 386857 388408 - orf19.3395 386857 388408 1 388408 386857 388408 386876 orf19.10898|IPF9483.2|IPF9481.3|Contig4-2516_0002|orf6.4336|CA2435|CaO19.3395|IPF9483 Predicted membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS); induced by nitric oxide, oxidative stress, alpha pheromone; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr6 389172 390147 + orf19.3394 389172 390147 1 389172 390147 389358 389987 orf19.10897|IPF18467.2|IPF9480.1|Contig4-2516_0006|orf6.1807|orf6.4337|CA0714|CaO19.3394|CaO19.10897|IPF9480 Predicted ORF in Assemblies 19, 20 and 21; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 390054 391880 - orf19.3393 390054 391880 1 391880 390054 391842 390118 orf19.10896|IPF23819.1|IPF9477.2|Contig4-2516_0008|orf6.1808|CA0715|DBP9|CaO19.10896|CaO19.3393 Putative DEAD-box helicase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 392047 392864 - orf19.3392 392047 392864 1 392864 392047 392806 392084 DOG1 orf19.10895|IPF23846.1|IPF9474.2|DOG2|Contig4-1966_0001|Contig4-2516_0009|orf6.1809|CA0716|CaO19.3392|CaO19.10895 Putative 2-deoxyglucose-6-phosphatase; haloacid dehalogenase hydrolase/phosphatase superfamily; similar to S. cerevisiae Dog1p, Dog2p, Hor1p, and Rhr2p; regulated by Nrg1p, Tup1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 393713 394691 + orf19.3391 393713 394691 1 393713 394691 393777 394526 ADK1 orf19.8301|orf19.10894|IPF23845.1|IPF20062.1|IPF26639.1|IPF20093.1|Contig4-1966_0003|Contig4-2154_0002|orf6.3696|orf6.1810|CA1982|orf19.683|ADK12|CaO19.10894|CaO19.3391 Protein described as adenylate kinase; decreased expression in hyphae compared to yeast-form cells; macrophage-induced protein; adenylate kinase release can be used as a marker for cell lysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 394606 396365 - orf19.684 394606 396365 1 396365 394606 396286 394739 orf19.8302|orf19.10893|IPF23861.1|IPF16687.2|IPF26627.1|IPF9470.2|Contig4-2154_0003|orf6.3695|orf6.1811|CA1981|orf19.3390|CaO19.8302|PCF11|CaO19.684|IPF9470 Putative transcription factor with zinc finger DNA-binding motif; heterozygous null mutant exhibits hypersensitivity to parnafungin and cordycepin in the C. albicans fitness test [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 397039 398103 + orf19.685 397039 398103 1 397039 398103 397098 398012 YHM1 orf19.8303|IPF9468.2|IPF29742.1|IPF16978.2|Contig4-1684_0002|Contig4-2154_0005|orf6.3694|orf6.685|CA1980 Putative mitochondrial carrier protein; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 398379 399127 + orf19.685.1 398379 399127 1 398379 399127 398745 398978 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 398986 400767 - orf19.686 398986 400767 1 400767 398986 400699 399104 orf19.8304|IPF16976.3|IPF9577.2|Contig4-1684_0005|Contig4-2607_0006|orf6.3693|orf6.686|CA1979|CaO19.686|IPF9577 Predicted ORF in Assemblies 19, 20 and 21; regulated by Nrg1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 400911 402754 + orf19.687 400911 402754 1 400911 402754 400988 402673 orf19.8305|IPF26624.1|IPF9580.2|Contig4-2607_0005|orf6.3692|CA1978|CaO19.8305|CaO19.687|IPF9580 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 402571 403782 - orf19.687.1 402571 403782 2 403782|403244 403690|402571 403696 402823 RPL25 IPF26650.1|IPF9581.1|Contig4-2607_0004|CA1977|RPL25.3 ORF Predicted by Annotation Working Group; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 403966 404787 - orf19.688 403966 404787 1 404787 403966 404702 404055 orf19.8306|IPF26642.1|IPF9582.1|Contig4-2607_0002|orf6.3691|CA1976|CaO19.688|MRPS18|IPF9582 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 405984 407865 + orf19.689 405984 407865 1 405984 407865 405984 407801 PLB1 orf19.8307|IPF26625.1|IPF9584.2|Contig4-1818_0003|orf6.3690|CA1975|CaO19.689 Phospholipase B; required for wild-type host cell penetration and for wild-type virulence in mouse model of systemic infection; Hog1p-induced; predicted signal sequence, N-glycosylation, and possible Y phosphorylation site, not GPI anchor [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr6 409423 411252 + orf19.690 409423 411252 1 409423 411252 409423 411252 PLB2 orf19.8309|IPF11981.1|IPF29741.1|Contig4-2418_0004|orf6.1985|CA0825|CaO19.8309|CaO19.690 Putative phospholipase B; conserved catalytic region; 6 putative N-glycosylation motifs; predicted secretion signal; no GPI anchor predicted; fungal-specific (no human or murine homolog) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 409896 410334 - ntar_998 409896 410334 1 410334 409896 410146 410018 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 410460 411070 - ntar_999 410460 411070 1 411070 410460 411026 410841 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 411363 412812 - orf19.691 411363 412812 1 412812 411363 412675 411560 GPD2 orf19.8310|IPF26632.1|IPF11982.1|Contig4-2418_0003|orf6.1984|CA0824|CaO19.691|CaO19.8310 Similar to glycerol 3-P dehydrogenases; regulated by Ssn6p (colony morphology-related), Nrg1p, Efg1p; induced upon osmotic and oxidative stress (via Hog1p), cell wall regeneration, macrophage/pseudohyphal growth, core stress response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 414631 416136 - orf19.692 414631 416136 1 416136 414631 416044 414704 orf19.8311|orf19.11003|IPF23773.1|IPF12234.2|IPF26641.1|IPF11987.1|Contig4-2418_0008|orf6.1983|orf6.4369|CA2459|CA0823|orf19.3509|PEX20|CaO19.692|CaO19.8311|IPF11987.3eoc Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 416170 417587 - orf19.3508 416170 417587 1 417587 416170 417449 416316 orf19.11002|IPF23767.1|IPF12233.1|Contig4-2540_0001|orf6.4368|CA2458|CaO19.3508|CaO19.11002|IPF12233 Predicted ORF in Assemblies 19, 20 and 21; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 417855 419089 + orf19.3507 417855 419089 1 417855 419089 418020 418925 MCR1 orf19.11001|IPF23768.1|IPF12231.1|Contig4-2540_0002|orf6.4367|CA2457|CaO19.3507|CaO19.11001 Protein described as NADH-cytochrome-b5 reductase; soluble protein in hyphae; biofilm induced; alkaline downregulated; ketoconazole or flucytosine induced, farnesol-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 419093 421440 + orf19.3506 419093 421440 1 419093 421440 419093 420490 DBR1 orf19.11000|IPF23766.1|IPF12230.1|Contig4-2540_0003|orf6.4366|CA2456|CaO19.11000|CaO19.3506 Debranchase; homozygous mutant accumulates lariat intermediates of mRNA splicing [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 420687 421951 - ntar_1000 420687 421951 1 421951 420687 420908 420687 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 422054 424839 + orf19.3505 422054 424839 1 422054 424839 422257 424725 orf19.10999|IPF23765.1|IPF12228.2|Contig4-2880_0016|orf6.4365|CA2455|CaO19.3505|CaO19.10999|IPF12228 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr6 424878 426144 - orf19.3504 424878 426144 2 426144|425412 425928|424878 425969 425041 RPL23A orf19.10998|IPF23772.1|IPF9946.1|RPL23B|Contig4-2880_0015|orf6.4364|CA2454|RPL23B.3 Putative ribosomal protein; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 425580 425888 + orf19.3503 425580 425888 1 425580 425888 425580 425888 orf19.10997|IPF23774.1|IPF28752.1|orf6.4363|CaO19.10997|CaO19.3503 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 426411 429683 - orf19.3501 426411 429683 1 429683 426411 429683 426543 orf19.10995|IPF9950.2|IPF28751.1|Contig4-2880_0012|orf6.4361|CA2453|CaO19.3501|CaO19.10995|IPF9950 Predicted ORF in Assemblies 19, 20 and 21; Hog1p-downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr6 434456 434959 + orf19.3499 434456 434959 1 434456 434959 434456 434959 orf19.10993|IPF9955.1|IPF18868.2|Contig4-2880_0005|orf6.4359|CA2452|LDG8|CaO19.3499|IPF9955 Predicted ORF in Assemblies 19, 20 and 21; regulated by Tsa1p, Tsa1Bp under H2O2 stress conditions; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr6 435457 436201 - ntar_1001 435457 436201 1 436201 435457 435727 435566 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 436330 437663 + orf19.3498 436330 437663 1 436330 437663 436421 437512 orf19.10992|IPF9957.2|IPF14060.2|Contig4-2880_0003|orf6.1942|orf6.4358|CA0802|CaO19.3498|IPF14060 Predicted ORF in Assemblies 19, 20 and 21; predicted enzyme of arginine degradation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 437835 443207 + orf19.3496 437835 443207 1 437835 443207 438049 443028 orf19.10990|IPF23771.1|IPF14063.2|Contig4-2880_0001|Contig4-2880_0002|orf6.1940|CA0801|CaO19.10990|CHC1|CaO19.3496 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 443143 444407 - orf19.3494 443143 444407 1 444407 443143 444305 443205 CTF5 orf19.10988|IPF23769.1|IPF14064.2|Contig4-2880_0017|orf6.1938|CA0800|MCM21|CaO19.10988|CaO19.3494|IPF14064 Protein induced during the mating process; transcription is repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 444551 447804 + orf19.3453 444551 447804 1 444551 447804 444675 447635 orf19.10957|IPF23775.1|IPF9785.2|Contig4-2892_0004|orf6.1812|CA0717|CaO19.10957|CaO19.3453|IPF9785 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 447600 449243 - orf19.3455 447600 449243 1 449243 447600 449123 447762 orf19.10959|IPF23788.1|IPF9782.1|Contig4-2892_0005|Contig4-2892_0006|orf6.1814|CA0718|CaO19.10959|LPE10|CaO19.3455|IPF9782 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 449498 451367 + orf19.3456 449498 451367 1 449498 451367 449592 451262 orf19.10960|IPF23784.1|IPF9779.2|Contig4-2892_0008|Contig4-2892_0009|orf6.1815|CA0719|CaO19.3456|IPF9779.5 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 451019 452564 - orf19.3457 451019 452564 1 452564 451019 452456 451305 SWD3 orf19.10961|IPF9778.1|IPF17933.2|Contig4-2892_0010|orf6.1816|orf6.3760|CA0720|CaO19.3457|IPF17932 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 452909 453859 + orf19.3458 452909 453859 1 452909 453859 453159 453704 orf19.10962|IPF9777.2|IPF17934.2|Contig4-2892_0013|orf6.1817|orf6.3761|CA2026|CaO19.3458|IPF9777 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 453905 456302 - orf19.3459 453905 456302 1 456302 453905 455539 454319 orf19.10963|IPF9776.2|IPF28754.1|Contig4-2892_0016|orf6.3762|CA2027|MCK1|CaO19.3459|CaO19.10963 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 458168 458684 - orf19.3460 458168 458684 1 458684 458168 458642 458241 orf19.10964|IPF9771.2|IPF14969.1|Contig4-2623_0001|Contig4-2892_0018|orf6.3763|orf6.994|CaO19.3460 Putative protein of unknown function; mRNA binds to She3p; transcription is regulated upon yeast-hyphal switch [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr6 460114 460792 - ntar_1002 460114 460792 1 460792 460114 460675 460502 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 460118 460852 + orf19.3461 460118 460852 1 460118 460852 460187 460549 orf19.10965|IPF23797.1|IPF14968.2|Contig4-2623_0003|orf6.3764|orf6.995|CA0254|CaO19.3461|IPF14968 Predicted ORF in Assemblies 19, 20 and 21; oxidative stress-induced via Cap1p; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr6 461325 462413 + orf19.3462 461325 462413 2 461325|461679 461520|462413 461502 462232 SAR1 orf19.10966|IPF13117.2|IPF28755.1|Contig4-2623_0005|orf6.3765|CA2029|CaO19.3462|CaO19.10966|SAR1.3f|SAR1.3 Functional homolog of S. cerevisiae Sar1p, which is required for ER-to-Golgi protein transport; binds GTP; similar to small GTPase superfamily proteins; gene has intron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 463099 465310 + orf19.3463 463099 465310 1 463099 465310 463176 465230 orf19.10967|IPF23780.1|IPF13116.1|Contig4-2623_0007|orf6.3766|CA2030|LSG1|CaO19.10967|CaO19.3463|IPF13116 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 465251 466097 - orf19.3465 465251 466097 1 466097 465251 466025 465372 RPL10A orf19.10969|IPF23796.1|IPF13114.1|RPL1B|Contig4-2623_0008|orf6.3768|CA2031|CaO19.10969|RPL1|CaO19.3465 Predicted ribosomal protein; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 466317 467625 + orf19.3466 466317 467625 1 466317 467625 466435 467574 orf19.10970|IPF23794.1|IPF13112.2|orf6.3769|CA2032|CaO19.3466|CaO19.10970|IPF13112 Predicted ORF in Assemblies 19, 20 and 21; decreased transcription is observed upon fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 467614 470771 - orf19.3467 467614 470771 1 470771 467614 470604 467785 orf19.10971|IPF16985.2|IPF19248.2|orf6.3770|orf6.498|CA2033|SEC27|CaO19.3467 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 470929 473004 - orf19.3468 470929 473004 1 473004 470929 472911 471082 ALG11 orf19.10972|IPF23781.1|IPF19249.1|orf6.3771|orf6.497|CA0095|CaO19.3468 Protein with similarity to mannosyltransferases [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 474094 475562 + orf19.3469 474094 475562 1 474094 475562 474249 475436 orf19.10973|IPF15632.2|IPF19086.2|Contig4-2269_0001|orf6.257|orf6.961|CA0040|CaO19.3469|IPF15632 Predicted ORF in Assemblies 19, 20 and 21; greater mRNA abundance observed in a cyr1 homozygous null mutant than in wild type [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 475578 478189 - orf19.3470 475578 478189 1 478189 475578 478131 475750 orf19.10974|orf6.962|IPF16554.3|IPF15630.2|Contig4-2269_0004|orf6.256|orf6.4989|CA0241|CaO19.3470|IPF15630 Putative flavodoxin; similar to S. cerevisiae Ypl207p; predicted Kex2p substrate [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 478383 479218 - orf19.3471 478383 479218 1 479218 478383 479034 478693 orf19.10975|IPF23800.1|IPF12047.2|Contig4-2835_0024|orf6.4988|orf6.963|CA0242|CaO19.3471|IPF12047 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 479180 481249 + orf19.3473 479180 481249 1 479180 481249 479519 481168 orf19.10977|IPF12049.2|IPF12048.3|Contig4-2835_0023|orf6.4986|orf6.965|CA2905|CaO19.3473|IPF12049 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 481282 483033 - orf19.3474 481282 483033 1 483033 481282 482963 481371 IPL1 orf19.10978|IPF23787.1|IPF12051.2|Contig4-2624_0002|Contig4-2835_0022|orf6.4985|CA2904|CaO19.10978|CaO19.3474 Predicted ORF in Assemblies 19, 20 and 21; induced during planktonic growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 481516 481699 + ntar_1003 481516 481699 1 481516 481699 481577 481699 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 485207 485580 - ntar_1004 485207 485580 1 485580 485207 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 486337 487385 + orf19.3475 486337 487385 1 486337 487385 486570 487130 orf19.10979|IPF11725|IPF11725.2|IPF12058.2|Contig4-2835_0016|orf6.432|orf6.4984|CA2903|CaO19.3475 Described as a Gag-related protein; hyphal induced; downregulation correlates with clinical development of fluconazole resistance; repressed by nitric oxide, 17-beta-estradiol, ethynyl estradiol [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 489079 491552 + orf19.3476 489079 491552 1 489079 491552 489921 491222 orf19.10980|IPF23792.1|IPF11729.2|Contig4-1746_0004|Contig4-2835_0008|orf6.4983|CA2902|HRR25|CaO19.10980|CaO19.3476 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 491396 493382 - orf19.3477 491396 493382 2 493382|492993 493102|491396 493340 491532 orf19.10981|IPF23776.1|IPF23791.1|IPF11731.2|IPF11730.2|Contig4-2835_0006|orf6.4982|CA2901|PUS1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 493128 493313 + ntar_1005 493128 493313 1 493128 493313 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 493455 494281 + orf19.3478 493455 494281 1 493455 494281 493633 494178 NIP7 orf19.10982|IPF23795.1|IPF11733.2|Contig4-2835_0001|orf6.4981|CA2900|CaO19.10982|CaO19.3478 Protein described as a nucleolar protein with role in ribosomal assembly; hyphal induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 494246 495846 - orf19.3480 494246 495846 1 495846 494246 495792 494341 orf19.10984|IPF23789.1|IPF17681.2|Contig4-1435_0004|orf6.4979|CA2899|CaO19.10984|RSM23|CaO19.3480|IPF17681 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 496091 499011 + orf19.3481 496091 499011 1 496091 499011 496121 497788 orf19.10985|IPF23785.1|IPF15646.2|Contig4-2024_0003|orf6.4978|CA2898|CaO19.10985|CaO19.3481|IPF15646 Putative protein of unknown function, transcription is activated in the presence of elevated CO2; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 499192 500833 + orf19.3482 499192 500833 1 499192 500833 499269 500660 orf19.10986|IPF23790.1|IPF14979.2|Contig4-2065_0003|orf6.4977|CA2897|CaO19.10986|NPY1|CaO19.3482|IPF14979 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 501440 502924 + orf19.3483 501440 502924 1 501440 502924 501608 502825 orf19.10987|IPF23793.1|IPF14981.2|Contig4-2065_0001|orf6.4976|CA2896|CaO19.3483|CaO19.10987|IPF14981 Predicted ORF in Assemblies 19, 20 and 21; Plc1p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 503322 507351 + orf19.5510 503322 507351 1 503322 507351 503452 507309 orf19.12956|IPF21645.1|IPF19759.1|Contig4-2439_0001|Contig4-2439_0002|orf6.4452|CA2515|CaO19.12956|CaO19.5510|IPF19759 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 507321 508273 - orf19.5513 507321 508273 1 508273 507321 508241 507381 orf19.12959|IPF21606.1|IPF4310.1|Contig4-2439_0003|orf6.4455|CA2516|PRP45|CaO19.12959|CaO19.5513|IPF4301 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 508921 509905 + orf19.5514 508921 509905 1 508921 509905 509019 509822 orf19.12960|IPF21610.1|IPF4311.2|Contig4-2439_0005|orf6.4456|CA2517|CaO19.5514|CaO19.12960|IPF4311 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 509827 510958 - orf19.5515 509827 510958 1 510958 509827 510906 509926 orf19.12961|IPF21602.1|IPF4312.2|Contig4-2439_0006|orf6.4457|CA2518|CaO19.12961|CBP3|CaO19.5515 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 511155 513300 + orf19.5516 511155 513300 1 511155 513300 511198 513105 orf19.12962|IPF21582.1|IPF4313.2|orf6.4458|CA2519|SRP72|CaO19.5516|CaO19.12962 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 513497 516800 - orf19.5518 513497 516800 1 516800 513497 516545 515805 orf19.12964|IPF16093.2|IPF4317.1|Contig4-1777_0004|Contig4-2188_0004|orf6.4460|orf6.745|CA2521|CaO19.5518|IPF4317 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 514179 515803 + orf19.5517 514179 515803 1 514179 515803 514411 515520 orf19.12963|IPF20046.1|IPF20104.1|Contig4-1777_0002|Contig4-2188_0003|orf6.4459|orf6.746|CA2520|ADH7|CaO19.5517|IPF20104 Similar to alcohol dehydrogenases; increased transcription is observed upon benomyl treatment; induced by nitric oxide; induced in core stress response; oxidative stress-induced via Cap1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 516198 516618 + ntar_1006 516198 516618 1 516198 516618 516259 516408 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 517614 517987 + ntar_1007 517614 517987 1 517614 517987 517829 517987 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 517705 519178 - orf19.5519 517705 519178 1 519178 517705 519054 517870 GCV1 orf19.12965|orf6.774|IPF16091.1|IPF4318.2|orf6.4461|orf6.744|CA2522 Protein described as T subunit of glycine decarboxylase; transcription is negatively regulated by Sfu1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 519397 519843 - orf19.5520 519397 519843 1 519843 519397 519843 519397 ASG7 orf19.12966|IPF16090.2|IPF4319.1|Contig4-2690_0015|orf6.4462|orf6.743|CA2523|CaO19.5520|IPF4319 Predicted ORF in Assemblies 19, 20 and 21; specific to a-cells; transcription is induced in response to alpha pheromone in SpiderM medium; member of conserved Mcm1p regulon [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 520749 521827 + orf19.5521 520749 521827 1 520749 521827 520904 521713 ISA1 orf19.12967|orf6.4463|IPF21609.1|IPF4322.1|Contig4-2690_0011|CA2524|CaO19.5521|CaO19.12967|IPF4322 Reported to have possible role in iron-sulfur cluster biogenesis or cytoplasm-to-mitochondrion iron transport; alkaline downregulated; transcriptionally regulated by iron; expression greater in high iron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 521777 522492 - orf19.5522 521777 522492 1 522492 521777 522447 521995 orf19.12968|Contig4-2690_0009|IPF21612.1|IPF4324.2|orf6.4464|CA2525|CaO19.12968|CaO19.5522|IPF4324|IPF4324.3 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 522648 523432 - orf19.5523 522648 523432 1 523432 522648 523432 522752 orf19.12969|IPF4325.2|IPF27987.1|Contig4-2118_0003|Contig4-2690_0008|orf6.4465|orf6.873|CA0212|CaO19.5523|IPF4325 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 523600 524307 + orf19.5524 523600 524307 1 523600 524307 523600 524307 orf19.12970|IPF4326.2|IPF27986.1|Contig4-2118_0002|Contig4-2690_0007|orf6.4466|orf6.872|CA0211|CaO19.5524|IPF4326 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 524580 525770 + orf19.5525 524580 525770 1 524580 525770 524631 525677 orf19.12971|IPF4328|IPF4328.2|IPF27985.1|Contig4-2118_0001|Contig4-2690_0006|orf6.4467|orf6.871|CA0210|CaO19.5525 Protein abundance is affected by URA3 expression in the CAI-4 strain background; regulated by Efg1p and Efh1p; repressed by Rgt1p; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 525601 526748 - orf19.5526 525601 526748 1 526748 525601 526727 525729 SEC20 orf19.12972|IPF19118.2|IPF4329.2|Contig4-2690_0005|orf6.4468|orf6.870|CA2526|CaO19.5526 Essential protein; similar to S. cerevisiae Sec20p; depletion causes membrane accumulation and drug sensitivity; expression regulated by growth phase; O-mannosylation regulates proteolysis; does not complement S. cerevisiae sec20-1 mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 526909 528664 + orf19.5527 526909 528664 1 526909 528664 526931 528424 orf19.12973|IPF21588.1|IPF4331.1|Contig4-2690_0004|orf6.4469|CA2527|YMR285|NGL2|CaO19.5527|IPF4331 Predicted ORF in Assemblies 19, 20 and 21; similar to S. cerevisiae Ymr285p and Yml118p; gene transcribed divergently from SEC20 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 528239 529390 - orf19.5528 528239 529390 1 529390 528239 529251 528430 MOB1 orf19.12974|IPF19269.2|IPF4332.1|Contig4-2690_0001|orf6.4470|orf6.454|CA2528|CaO19.5528|CaO19.12974 Predicted ORF in Assemblies 19, 20 and 21; periodic mRNA expression, peak at cell-cycle G2/M phase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 529643 532347 + orf19.5530 529643 532347 1 529643 532347 529703 532213 NAB3 orf19.12976|IPF4338.2|IPF17959.3|Contig4-1760_0001|Contig4-1760_0002|orf6.1545|orf6.4471|orf6.452|CA0084|CaO19.5530 Predicted ORF in Assemblies 19, 20 and 21; flucytosine repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 532332 533942 - orf19.5531 532332 533942 1 533942 532332 533889 532363 CDC37 orf19.12977|IPF17957.3|IPF4339.1|orf6.1546|orf6.451|CA0551|CaO19.5531 Chaperone for Crk1p; interacts with Crk1p kinase domain and with Sti1p; putative phosphorylation site at Ser14; functional homolog of S. cerevisiae Cdc37p; likely to be essential for growth; regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 534150 534610 - orf19.5532 534150 534610 1 534610 534150 534590 534225 orf19.12978|IPF21634.1|IPF4340.1|orf6.1547|CaO19.12978|CaO19.5532 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr6 534944 537562 - orf19.5533 534944 537562 1 537562 534944 537435 535138 orf19.12979|IPF21578.1|IPF4343.2|orf6.1548|CA0552|CaO19.5533|VPS9|CaO19.12979|IPF4343 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 537798 539059 - orf19.5534 537798 539059 1 539059 537798 538985 537933 orf19.12980|IPF21604.1|IPF16653.1|Contig4-1697_0002|orf6.1549|CA0553|CaO19.5534|IPF16653 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 539205 541116 - orf19.5535 539205 541116 1 541116 539205 540796 539339 orf19.12981|IPF14381.1|IPF16655.3|Contig4-1697_0004|Contig4-2229_0002|Contig4-2229_0004|orf6.1141|orf6.1550|CA0332|FEN2|CaO19.5535 Predicted membrane transporter, member of the anion:cation symporter (ACS) family, major facilitator superfamily (MFS) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 540968 541335 + ntar_1008 540968 541335 1 540968 541335 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 541743 543461 - orf19.5536 541743 543461 1 543461 541743 543461 541743 orf19.12982|IPF14383.2|IPF27977.1|Contig4-2229_0001|orf6.1140|orf6.3630|CA6224|AMD21|CaO19.5536|AMD2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 547431 549261 - orf19.5537 547431 549261 1 549261 547431 549062 547659 orf19.12983|IPF21592.1|IPF9126.1|Contig4-2737_0011|orf6.3629|CA1924|WSC2|CaO19.5537|IPF9126 Putative protein of unknown function; mRNA binds to She3p; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr6 552141 553665 + orf19.5539 552141 553665 1 552141 553665 552719 553561 orf19.12985|IPF18814.2|IPF9130.2|Contig4-2737_0004|orf6.2207|orf6.3627|CA1923|CaO19.5539|IPF9130 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 553576 556277 - orf19.5541 553576 556277 1 556277 553576 556040 554106 orf19.12987|IPF9132.2|IPF27973.1|Contig4-2737_0003|orf6.2205|orf6.3625|YPL184|CA0969|CaO19.5541|IPF9132 Predicted ORF in Assemblies 19, 20 and 21; similar to S. pombe Nrd1p; transcription is induced upon induction of hyphal growth; regulated by Cph1p, Efg1p, Cph2p; low-level expression; alkaline upregulated; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 557602 558153 + ntar_1009 557602 558153 1 557602 558153 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 558311 559567 - orf19.5542 558311 559567 1 559567 558311 559567 558311 SAP6 orf19.12988|IPF12747.2|IPF9135.2|Contig4-2734_0005|orf6.2204|orf6.3624|CA0968|CaO19.5542 Secreted aspartyl proteinase; expressed upon hyphal growth, during oral carriage, mucosal, systemic infections; sap4 sap5 sap6 triple mutant has defects in systemic virulence, survival in macrophage, and protein utilization for nitrogen [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 561543 563978 - orf19.5543 561543 563978 1 563978 561543 563978 561543 orf19.12989|IPF20070.1|IPF19863.2|Contig4-2830_0003|orf6.1300|CA0967|CaO19.5543|VPS183|VPS184 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr6 564434 566542 + orf19.5544 564434 566542 1 564434 566542 564471 566414 SAC6 orf19.12990|orf19.12992|IPF18815.2|IPF8093.2|Contig4-1909_0001|orf6.1297|orf6.1299|orf6.2202|CA0408|CA0407|orf19.5546|IPF14432.2|SAC6.3f|SAC6.5f Transcription is regulated by Nrg1p and Mig1p; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 566686 567207 + orf19.5547 566686 567207 1 566686 567207 566751 567074 orf19.12993|IPF19861.2|IPF19862.1|Contig4-2173_0008|orf6.1296|CA0406|CaO19.5547|IPF19862.5f|CA0405|IPF19862.3f|IPF19861.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 567191 569129 - orf19.5548 567191 569129 1 569129 567191 569040 567262 LYS14|orf19.12994|IPF21583.1|IPF14435.1|Contig4-2173_0005|Contig4-2173_0006|Contig4-2462_0002|orf6.1295|orf6.4118|CA0404|CaO19.5548 Putative transcription factor with zinc cluster DNA-binding motif; has similarity to S. cerevisiae Lys14p, which is a transcription factor involved in the regulation of lysine biosynthesis genes [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 569400 570125 + orf19.5549 569400 570125 1 569400 570125 569428 570105 orf19.12995|IPF12637.1|IPF14438.1|Contig4-2173_0002|Contig4-2173_0003|Contig4-2462_0003|Contig4-2462_0004|orf6.1294|orf6.4119|CA2282|CaO19.5549|IPF14438 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 570281 571427 + orf19.5550 570281 571427 1 570281 571427 570398 571090 MRT4 orf19.12996|IPF12634.2|IPF14441.2|Contig4-2462_0007|orf6.4120|CA2283|CaO19.12996|CaO19.5550 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to tubercidin (7-deazaadenosine); transcription is upregulated in both intermediate and mature biofilms [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 571368 573178 - orf19.5551 571368 573178 1 573178 571368 573084 571522 MIF2 orf19.12997|IPF21589.1|IPF12632.1|Contig4-2462_0009|Contig4-2462_0010|orf6.4121|CA2284|CaO19.12997|CaO19.5551 Centromere-associated protein; similar to CENP-C proteins; Cse4p and Mif2p colocalize at C. albicans centromeres [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 573433 575710 - orf19.5552 573433 575710 1 575710 573433 575657 573450 orf19.12998|IPF21580.1|IPF12629.2|Contig4-2462_0013|orf6.4122|CA2285|CaO19.5552|CaO19.12998|IPF12629 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 576221 577187 + orf19.5553 576221 577187 1 576221 577187 576424 576951 orf19.12999|IPF21615.1|IPF5369.2|orf6.4123|CA2286|CaO19.5553|CaO19.12999|IPF5369 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 577090 580759 - orf19.5555 577090 580759 1 580759 577090 580595 577200 orf19.13001|IPF21642.1|IPF5373.2|Contig4-3002_0017|orf6.4125|CA2287|CaO19.5555|CaO19.13001|IPF5373 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 582808 583116 + orf19.5556 582808 583116 1 582808 583116 582808 583116 orf19.13002|IPF21643.1|IPF28005.1|orf6.4126|CaO19.13002|CaO19.5556 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 583091 584510 - ntar_1010 583091 584510 1 584510 583091 583788 583648 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 583682 586402 + orf19.5557 583682 586402 1 583682 586402 583682 586300 MNN4-4 orf19.13003|orf6.4127|MNT4|IPF21572.1|IPF5376.2|Contig4-3002_0015|MNN4|CA2288|CaO19.13003|MNN45|CaO19.5557|IPF5376 Putative mannosyltransferase; transcription is upregulated in a mutant lacking the Ssk1p response regulator proteinor in a nik1 homozygous null mutant, but not in chk1 or sln1 null mutants; pheromone induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr6 584950 585608 - ntar_1011 584950 585608 1 585608 584950 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 586454 588485 - orf19.5558 586454 588485 1 588485 586454 588152 586548 RBF1 orf19.13004|IPF5380.3|IPF27978.1|Contig4-3002_0014|orf6.3253|orf6.4128|CA2289|CaO19.5558|RBF1.3|IPF5380.2 Transcription factor; glutamine-rich activation domain; binds RPG-box DNA sequences; predominantly nuclear; antigenic during human oral infection; mutation causes accelerated induction of filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 588754 590289 + orf19.5559 588754 590289 1 588754 590289 588852 589919 STE23 orf19.13005|IPF19660.2|IPF19661.1|Contig4-3002_0013|orf6.3252|orf6.4129|CA1654|CaO19.5559|IPF19660 Protein similar to S. cerevisiae Ste23p, which is involved in maturation of pheromone; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 590369 593818 + orf19.5561 590369 593818 1 590369 593818 590389 593712 RAV2 orf19.13007|IPF21644.1|IPF5385.2|Contig4-3002_0010|orf6.3250|CA1653|CaO19.5561|STE23|CaO19.13007 Protein similar to S. cerevisiae Rav2p, which is involved in acidification of the vacuole; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr6 594263 595245 + orf19.5563 594263 595245 1 594263 595245 594426 595127 RNH1 orf19.13009|IPF19318.2|IPF5387.1|Contig4-3002_0008|orf6.3247|orf6.3248|orf6.376|CA1652|RNH11|RNH1.exon1 Protein described as Ribonuclease H (RNAse H); hyphal-induced; flucytosine induced; similar to orf19.5564 (see Locus History) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 594523 595189 - ntar_1012 594523 595189 1 595189 594523 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 595620 595859 + ntar_1013 595620 595859 1 595620 595859 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 596314 597545 + orf19.5564 596314 597545 1 596314 597545 596555 597253 orf6.3247|CA1651|orf19.13010|Contig4-3002_0007|RNH12|RNH1.exon2|IPF18639.1 Predicted ORF in Assemblies 19, 20 and 21; was merged with orf19.5563 by Annotation Working Group and subsequently reinstated; similar to RNH1 (see Locus History) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 597625 598876 - orf19.5565 597625 598876 1 598876 597625 598758 597694 orf19.13011|IPF19317.2|IPF5389.2|Contig4-3002_0004|orf6.3246|orf6.377|CA1650|CaO19.5565|IPF5389 Putative 3-hydroxyisobutyrate dehydrogenase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 599767 601376 - orf19.5566 599767 601376 1 601376 599767 601332 599971 orf19.13012|IPF21594.1|IPF5392.2|Contig4-3002_0002|Contig4-3002_0003|orf6.3245|CA1649|CaO19.13012|CaO19.5566|LAB1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 601435 602505 + orf19.5567 601435 602505 1 601435 602505 601481 602320 POP4 orf19.13013|IPF21607.1|IPF16662.2|Contig4-3002_0001|orf6.3244|CA1648|CaO19.5567|CaO19.13013|IPF16662 Protein likely to be essential for growth, based on an insertional mutagenesis strategy; similar to S. cerevisiae Pop4p, which is a subunit of both RNase MRP and nuclear RNase P; filament induced; regulated by Nrg1p, Tup1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 602221 603366 - orf19.5568 602221 603366 1 603366 602221 603302 602352 VPS51 orf19.13014|IPF12479.3|IPF16663.1|orf6.3243|orf6.1357|CA1647|CaO19.5568|IPF16663 Protein with a role in vacuolar function; null mutant has defect in damaging oral epithelial and vascular endothelial cells; required for normal hyphal growth and stress resistance; induced in presence of host oral or vascular cells [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 603496 606562 + orf19.5569 603496 606562 3 603496|603672|606014 603592|605941|606562 603574 606523 orf19.13015|orf19.13017|IPF12473|IPF12478.1|IPF16667.3|Contig4-2518_0001|Contig4-2518_0002|orf6.1358|orf6.1360|orf6.3242|CA0439|orf19.5571|SCRC1|CA0440|IPF12473.2|IPF12478 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 606535 608295 - orf19.5572 606535 608295 1 608295 606535 608019 606721 orf19.13018|IPF12472.2|IPF27979.1|Contig4-2518_0003|orf6.1361|CA0441|CaO19.13018|CaO19.5572|IPF12472 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 608310 608569 + ntar_1014 608310 608569 1 608310 608569 608314 608475 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 608853 609935 - orf19.5573 608853 609935 1 609935 608853 609935 608853 orf19.13019|IPF18988.2|IPF12470.2|Contig4-2518_0004|Contig4-2518_0005|orf6.1362|orf6.1720|CA0656|HRQ4|CaO19.5573|IPF12470 Predicted ORF in Assemblies 19, 20 and 21; decreased expression observed in an ssr1 homozygous null mutant [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 610230 610449 - ntar_1015 610230 610449 1 610449 610230 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 610516 612037 + orf19.5574 610516 612037 1 610516 612037 610556 611752 orf19.13020|IPF21600.1|IPF19877.1|Contig4-2518_0008|orf6.1721|CA0657|CaO19.5574|IPF19877 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 611763 613604 - orf19.5575 611763 613604 1 613604 611763 613501 611882 orf19.13021|IPF21586.1|IPF16505.2|Contig4-1786_0007|Contig4-1786_0008|Contig4-2518_0009|orf6.1722|CA0658|PEX25|CaO19.5575|IPF16505 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 614198 616466 - orf19.5576 614198 616466 1 616466 614198 616211 614547 orf19.13022|orf19.13023|IPF21625.1|IPF16507.2|Contig4-1786_0001|orf6.1723|orf6.1724|YDR531W|CA0659|CA0660|orf19.5577|IPF16189.3f Protein similar to S. cerevisiae Ydr531wp; transposon mutation affects filamentous growth; downregulated in core stress response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 618014 619884 + orf19.5578 618014 619884 1 618014 619884 618073 619764 orf19.13024|IPF17542.3|IPF27975.1|orf6.1645|orf6.1725|CA0611|CaO19.5578|IPF17542|IPF17542.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 619895 621110 - orf19.5579 619895 621110 1 621110 619895 621078 620272 orf19.13025|IPF21608.1|IPF17545.2|Contig4-2246_0001|Contig4-2246_0002|orf6.1646|CA0612|CaO19.5579|CaO19.13025|IPF17545 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 621290 630018 + orf19.5580 621290 630018 1 621290 630018 621290 629911 orf19.13026|IPF21605.1|IPF15888.3|orf6.1647|orf6.4422|CA2497|TEL1|CaO19.5580|TEL1.3eoc|IPF15888.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr6 630611 633043 + orf19.5584 630611 633043 1 630611 633043 630611 633043 PEP3 orf19.13030|IPF21577.1|IPF19951.1|Contig4-2734_0001|orf6.4426|CA2498|CaO19.5584|VPS181 Peptidase; activity useful for strain identification by multilocus enzyme electrophoresis (MLEE); clade-associated gene expression [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr6 635336 636592 + orf19.5585 635336 636592 1 635336 636592 635336 636592 SAP5 orf19.13032|IPF21596.1|IPF6816.1|Contig4-2830_0009|orf6.4427|CA2499|CaO19.5585|CaO19.13032 Secreted aspartyl proteinase; sap4 sap5 sap6 triple mutant has defects in virulence and utilization of protein as N source; expressed in mucosal and systemic infections; absent from C. dubliniensis; mRNA is localized to hyphal tip via She3p [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr6 637322 640411 - orf19.5586 637322 640411 1 640411 637322 640365 637417 orf19.13033|IPF21569.1|IPF6814.1|Contig4-2830_0010|orf6.4428|CA2500|FIG4 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 640497 642229 - orf19.5587 640497 642229 1 642229 640497 641999 640599 orf19.13034|IPF21593.1|IPF6812.2|Contig4-2830_0011|Contig4-2830_0013|orf6.4429|CA2501|CaO19.5587|IPF6812 Putative protein of unknown function, transcription is upregulated in clinical isolates from HIV+ patients with oral candidiasis; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 643694 645919 + orf19.5588 643694 645919 1 643694 645919 643694 645919 PGA60 orf19.13035|IPF20061.1|IPF20103.1|Contig4-2698_0010|orf6.1759|orf6.4430|CA2502|CaO19.5588|IPF20103 Putative GPI-anchored protein of unknown function; hyphal-induced expression [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 646325 646648 - orf19.5589 646325 646648 1 646648 646325 646648 646325 IPF28003.1|orf6.4431|CaO19.5589 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 646776 647893 - orf19.5591 646776 647893 1 647893 646776 647819 646776 ADO1 orf19.13037|IPF6804.2|IPF27983.1|Contig4-2698_0008|orf6.1761|orf6.4433|CA0685|CaO19.5591 Putative protein of unknown function; heterozygous null mutant exhibits resistance to cordycepin in the C. albicans fitness test; ketoconazole-induced; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 648633 650654 + orf19.5592 648633 650654 1 648633 650654 648633 650654 orf19.13038|IPF16583.2|IPF6803.1|Contig4-2698_0007|orf6.1762|orf6.4434|orf6.4435|CA2503|CA2504|orf19.5593|IPF6803.5f [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 651917 653952 + orf19.5595 651917 653952 1 651917 653952 652332 653891 SHE3 orf19.13040|IPF16588.3|IPF6796.2|Contig4-2698_0002|orf6.4437|CA2505|CaO19.13040|CaO19.5595|IPF6796 mRNA-binding protein that localizes specific mRNAs to daughter yeast-form cells and to hyphal tips; required for normal filamentous growth and host epithelial cell damage; ortholog of S. cerevisiae She3p but set of target mRNAs differs [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 653872 655123 - orf19.5596 653872 655123 1 655123 653872 655101 653968 orf19.13041|IPF17371.2|IPF6794.2|Contig4-2698_0001|orf6.4438|orf6.971|CA2506|CaO19.5596|IPF6794 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 655260 658567 + orf19.5597 655260 658567 1 655260 658567 655323 658490 POL5 orf19.13042|IPF6793.3|Contig4-3004_0007|orf6.4439|orf6.5074|orf6.972|CA0245|CA6298|orf19.5598|POL5.5f|IPF17372.2 Predicted ORF in Assemblies 19, 20 and 21; induced upon biofilm formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 658687 659349 + orf19.5597.1 658687 659349 1 658687 659349 658776 658967 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 659162 661634 - orf19.5599 659162 661634 1 661634 659162 661595 659244 MDL2 orf19.13043|IPF20121.1|Contig4-2108_0001|orf6.170|orf6.973|orf6.5073|orf6.5072|CA2972|CA2971|orf19.5600|MDL2.3f Putative mitochondrial, half-size MDR-subfamily ABC transporter [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 661800 663171 - orf19.5601 661800 663171 1 663171 661800 663171 661948 orf19.13044|IPF19412.2|IPF14448.2|Contig4-2108_0002|orf6.171|orf6.5071|CA2970|CaO19.5601|IPF14448 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 661858 662157 + ntar_1016 661858 662157 1 661858 662157 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 663300 665386 - orf19.5602 663300 665386 1 665386 663300 665322 663382 BMT6 orf19.13045|IPF21591.1|IPF19772.1|Contig4-2108_0003|orf6.5070|CA2969|WRY2|CaO19.5602|IPF19772 Putative beta-mannosyltransferase, member of a 9-gene family that includes characterized genes BMT1, BMT2, BMT3, and BMT4 with roles in beta-1,2-mannosylation of cell wall phosphopeptidomannan; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 666548 668242 - orf19.5604 666548 668242 1 668242 666548 668242 666548 MDR1 orf19.13047|BENR|BMR1|Contig4-1827_0002|BEN|IPF21587.1|IPF16346.2|orf6.5068|CA2968|BEN1|CaO19.13047|CaO19.5604 Multidrug efflux pump of plasma membrane; member of the MDR family of major facilitator transporter superfamily; methotrexate is preferred substrate; overexpression in drug-resistant clinical isolates confers fluconazole resistance [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 669112 669411 + ntar_1017 669112 669411 1 669112 669411 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 669357 672602 - orf19.5605 669357 672602 1 672602 669357 672439 669449 orf19.13048|IPF21655.1|IPF12513.2|orf6.5067|CA2967|CaO19.5605|CaO19.13048|IPF12513 Predicted ORF in Assemblies 19, 20 and 21; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 672990 673310 - orf19.5606 672990 673310 1 673310 672990 673310 672990 orf19.13049|IPF16438.2|IPF28008.1|Contig4-2044_0003|orf6.5066|orf6.94|CaO19.5606 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 674186 675441 + orf19.5607 674186 675441 1 674186 675441 674328 675269 orf19.13050|IPF16435.3|IPF16278.1|Contig4-1929_0002|orf6.5065|orf6.93|CA6225|CaO19.5607|IPF16278 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 675292 676484 - orf19.5608 675292 676484 1 676484 675292 676416 675424 orf19.13051|IPF21599.1|IPF16279.2|Contig4-1929_0001|orf6.5064|CA2966|CaO19.5608|RPC34|CaO19.13051 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 676541 677778 + orf19.5609 676541 677778 1 676541 677778 676630 677715 orf19.13052|IPF21598.1|IPF13174.2|Contig4-2392_0011|orf6.5063|CA2965|CaO19.13052|CaO19.5609|IPF13174 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 678014 679231 + orf19.5610 678014 679231 1 678014 679231 678124 679161 ARG3 orf19.13053|IPF21601.1|IPF13176.2|Contig4-2392_0010|orf6.5062|CA2964|CaO19.13053|CaO19.5610|IPF13176.3 Alkaline downregulated; Gcn4p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 679563 680594 + orf19.5611 679563 680594 1 679563 680594 679563 680594 orf19.13054|IPF21597.1|IPF13178.2|Contig4-2392_0005|Contig4-2392_0007|orf6.5061|CA2963|CaO19.13054|GRE21|CaO19.5611|GRP3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 681023 681247 - ntar_1018 681023 681247 1 681247 681023 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 682711 685269 + orf19.5612 682711 685269 1 682711 685269 682872 685241 BMT4 orf19.13055|IPF15015.2|IPF13180.3|Contig4-2391_0004|orf6.1045|orf6.5060|orf6.728|CA0276|CaO19.5612|WRY1|IPF15015 Putative beta-mannosyltransferase, required for elongation of beta-mannose chains on the acid-labile fraction of cell wall phosphopeptidomannan; member of a 9-gene family; regulated by Tsa1p, Tsa1Bp [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 683536 683783 - ntar_1019 683536 683783 1 683783 683536 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 685750 686858 + orf19.5614 685750 686858 1 685750 686858 685914 686771 orf19.13057|IPF12328.2|IPF15019.1|Contig4-2391_0003|orf6.1047|orf6.726|CA0277|RNH11|CaO19.5614|RNH1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 686817 687978 - orf19.5615 686817 687978 1 687978 686817 687829 686936 AYR2 orf19.13060|IPF21613.1|IPF15021.2|Contig4-2391_0002|orf6.1049|orf6.4774|orf6.725|CA0163|CaO19.5615 Predicted ORF in Assemblies 19, 20 and 21; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 688419 689228 + orf19.5616 688419 689228 1 688419 689228 688419 689228 orf19.13061|IPF16804.1|IPF19168.1|Contig4-1981_0003|orf6.4775|orf6.724|CA0162|CaO19.5616|IPF19168 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 689412 691098 + orf19.5617 689412 691098 1 689412 691098 689479 690918 orf19.13062|IPF16806.1|IPF19169.2|Contig4-1981_0001|orf6.4776|orf6.723|CA2753|CaO19.5617|IPF16806 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 690967 693124 - orf19.5618 690967 693124 1 693124 690967 692998 691040 orf19.13063|IPF12432.2|IPF27971.1|Contig4-2504_0008|orf6.4777|CA2754|VPS45|CaO19.5618|CaO19.13063 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 693546 693788 - ntar_1020 693546 693788 1 693788 693546 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 693572 695997 + orf19.5619 693572 695997 1 693572 695997 693815 695932 orf19.13064|IPF12435.2|IPF19389.2|Contig4-2504_0006|orf6.213|orf6.4778|CA2755|LPF39|CaO19.5619|IFA12 Predicted ORF in Assemblies 19, 20 and 21; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 694341 695948 - ntar_1021 694341 695948 1 695948 694341 694605 694363 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 696296 697655 + orf19.5620 696296 697655 1 696296 697655 696408 697337 orf19.13065|IPF18418.1|IPF12436.3|Contig4-2504_0003|orf6.212|orf6.4779|CA2756|PHZ1|CaO19.5620|IPF18418 Predicted ORF in Assemblies 19, 20 and 21; regulated by Gcn4p; induced in response to amino acid starvation (3-aminotriazole treatment); increased transcription is observed upon benomyl treatment or in an azole-resistant strain that overexpresses MDR1 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 697147 700081 - orf19.5621 697147 700081 1 700081 697147 700043 697278 orf19.13066|IPF19767.1|IPF27969.1|Contig4-2504_0001|Contig4-2504_0002|Contig4-2504_0009|orf6.4780|CA2757|CaO19.5621|CaO19.13066|IPF19767 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to amphotericin B [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 700283 702701 - orf19.5622 700283 702701 1 702701 700283 702416 700362 GLC3 orf19.13067|IPF16449.2|IPF13786.3|Contig4-2165_0001|orf6.204|orf6.4781|CA2758|GLC3.3f Protein described as similar to 1,4-glucan branching enzyme; fluconazole-induced; shows colony morphology-related gene regulation by Ssn6p; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 703047 703217 + ntar_1022 703047 703217 1 703047 703217 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 703144 704904 - orf19.5623 703144 704904 1 704904 703144 704853 703444 ARP4 orf19.13069|IPF13789.2|IPF19829.2|Contig4-2165_0005|orf6.203|orf6.4783|CA6299|CA2759|orf19.5624|ARP4.3f Subunit of the NuA4 histone acetyltransferase complex [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 703428 703716 + ntar_1023 703428 703716 1 703428 703716 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 705084 705922 - orf19.5625 705084 705922 1 705922 705084 705675 705142 orf19.13070|IPF13790.1|IPF19156.2|Contig4-2165_0007|orf6.4784|orf6.737|CA6226|CaO19.5625|IPF19156|CA2760|IPF13790 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 707142 707345 - ntar_1024 707142 707345 1 707345 707142 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 709627 711704 + orf19.5626 709627 711704 1 709627 711704 710237 711466 orf19.13071|IPF15013.2|IPF27980.1|Contig4-2416_0007|orf6.4785|CA2761|CaO19.5626|IPF15013 Predicted ORF in Assemblies 19, 20 and 21; Plc1p-regulated; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 712075 713591 + orf19.5627 712075 713591 1 712075 713591 712332 713438 orf19.13072|IPF15012.2|IPF27981.1|Contig4-2416_0004|orf6.4786|CA2762|CaO19.5627|IPF15012 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 713548 713904 - ntar_1025 713548 713904 1 713904 713548 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 714521 715832 + orf19.5628 714521 715832 2 714521|714802 714681|715832 714650 715699 orf19.13073|IPF21603.1|IPF16773.2|Contig4-2416_0002|orf6.4787|CA2763|DIC1.3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 715757 716478 - orf19.5629 715757 716478 1 716478 715757 716405 716022 QCR7 orf19.13074|IPF21627.1|IPF16775.2|orf6.4788|CA2764|CaO19.5629|CaO19.13074 Protein described as ubiquinol-cytochrome-c reductase, subunit 7 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 716517 717819 - orf19.5630 716517 717819 1 717819 716517 717762 716662 APA2 orf19.13075|IPF18417.1|IPF27984.1|orf6.4789|CA2765|CaO19.5630 Protein described as ATP adenylyltransferase II; regulated by Gcn4p; repressed in response to amino acid starvation (3-aminotriazole treatment); increased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 717985 720214 + orf19.5701 717985 720214 1 717985 720214 718017 720212 orf19.13076|orf19.13124|IPF18416.1|IPF27982.1|IPF21471.1|IPF8472.2|orf6.4790|orf6.4631|CA2766|CA2653|orf19.5631|CaO19.13124|CaO19.5701|IPF8472.3eoc Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr6 719806 725166 - orf19.5702 719806 725166 1 725166 719806 725138 720336 orf19.13125|IPF21483.1|IPF8474.2|Contig4-2811_0027|orf6.4632|CA2654|CPS2|CaO19.13125|CaO19.5702|IPF8474 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 725489 727952 + orf19.5704 725489 727952 1 725489 727952 725539 727845 orf19.13127|IPF17898.2|IPF8477.1|Contig4-2522_0007|orf6.151|orf6.4634|CA2655|CaO19.5704|IPF8477 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 727883 730772 - orf19.5705 727883 730772 1 730772 727883 730726 727952 NAM2 orf19.13128|IPF17896.2|IPF19955.1|Contig4-2522_0005|Contig4-2522_0006|orf6.150|orf6.4635|CA2656|CaO19.5705 Putative mitochondrial leucyl-tRNA synthetase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr6 730940 734587 + orf19.5710 730940 734587 1 730940 734587 731023 734508 orf19.13133|IPF21499.1|IPF8486.2|orf6.4640|CA2657|NUP1|CaO19.5710|IPF8486 Putative protein of unknown function; mRNA binds to She3p; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 736412 736967 - ntar_1026 736412 736967 1 736967 736412 736709 736557 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 736573 736803 + ntar_1027 736573 736803 1 736573 736803 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 737082 739582 + orf19.5711 737082 739582 1 737082 739582 737504 739369 orf19.13134|IPF16951.2|IPF8105.1|Contig4-2608_0003|orf6.4641|orf6.532|CA2658|CaO19.5711|CSR1|IPF8105 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 740062 742009 + orf19.5713 740062 742009 1 740062 742009 740062 741930 YMX6 orf19.13136|IPF21452.1|IPF8102.2|Contig4-2608_0005|orf6.4643|CA2659|NDE1|NDH2|CaO19.5713|NDE2|CaO19.13136 Protein described as NADH dehydrogenase; macrophage-downregulated gene; induced by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr6 741886 743614 - orf19.5714 741886 743614 1 743614 741886 743271 742096 SAP1 orf19.13137|PRA10|CAP|PEP1|PEP10|OP1A|IPF21467.1|IPF8101.2|Contig4-2608_0006|orf6.4644|CA2660|CaO19.5714|CaO19.13137 Secreted aspartyl proteinase; acts in utilization of protein as nitrogen source; virulence role in mouse or guinea pig systemic infection, human or rat vaginal epithelium; regulated by growth phase, alpha-pheromone; produced by opaque cells [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 745130 746383 - orf19.5716 745130 746383 1 746383 745130 746383 745130 SAP4 orf19.13139|IPF21464.1|IPF8099.1|Contig4-2038_0003|orf6.3803|CA2055|CaO19.13139|CaO19.5716 Secreted aspartyl proteinase; sap4 sap5 sap6 triple mutant has defects in systemic virulence (mouse, guinea pig), survival in macrophage, and protein utilization for nitrogen; expressed during mucosal and systemic infections, oral carriage [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 747133 747480 - orf19.5717 747133 747480 1 747480 747133 747480 747133 orf19.13140|IPF21501.1|IPF8098.3|orf6.3802|CaO19.13140|CaO19.5717 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 748346 750781 - orf19.5718 748346 750781 1 750781 748346 750781 748346 orf19.13141|IPF11032.1|IPF21445.1|IPF19938.1|Contig4-1709_0001|Contig4-1709_0003|orf6.2203|orf6.3801|orf6.4426|orf6.513|orf6.621|CA0135|CA2054|orf19.1019|CaO19.5718|VPS182|VPS183|CaO19.13141 Predicted ORF in Assemblies 19, 20 and 21; merged with orf19.1019 in Assembly 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr6 751203 751365 + ntar_1028 751203 751365 1 751203 751365 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 751377 752244 - orf19.5719 751377 752244 1 752244 751377 752057 751656 orf19.13142|IPF11030.2|Contig4-2277_0005|orf6.622|orf6.3800|orf19.1020|CaO19.13142|CaO19.5719 Predicted ORF from Assembly 19; removed from Assembly 20; subsequently reinstated in Assembly 21 and merged with orf19.1020 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 752354 754071 + orf19.5720 752354 754071 1 752354 754071 752525 753922 orf19.13143|IPF21461.1|IPF11029.2|Contig4-2277_0003|orf6.3799|CA2053|CaO19.5720|CaO19.13143|IPF11029 Predicted membrane transporter, member of the monocarboxylate porter (MCP) family, major facilitator superfamily (MFS); ketoconazole or caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 753879 755745 - orf19.5722 753879 755745 1 755745 753879 755643 754024 orf19.13145|IPF21455.1|IPF11027.2|Contig4-2277_0001|orf6.3797|CA2052|CaO19.13145|CaO19.5722|IPF11027 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 756826 759084 + orf19.5723 756826 759084 1 756826 759084 756971 758962 POX1 orf19.13146|IPF21449.1|IPF11025.2|POX1-2|Contig4-3044_0020|Contig4-3044_0021|orf6.3796|CA2051|POX105|CaO19.13146|CaO19.5723|PXP5 Predicted acyl-CoA oxidase; expression is regulated upon white-opaque switching; upregulated upon phagocytosis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 759178 759900 + orf19.5724 759178 759900 1 759178 759900 759178 759900 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 760086 762407 + orf19.5725 760086 762407 1 760086 762407 760117 762378 orf19.13148|IPF12982.2|IPF18406.1|IPF18407.1|Contig4-3044_0018|orf6.3794|orf6.4904|orf6.4905|CA2049|CA6300|orf19.5726|IPF12982.5f|IPF12982 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr6 762168 762936 - orf19.5727 762168 762936 1 762936 762168 762899 762210 orf19.13149|IPF18553.1|IPF12981.2|Contig4-3044_0017|orf6.3793|orf6.4906|CA2841|CaO19.5727|IPF12981 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 763122 764938 - orf19.5728 763122 764938 1 764938 763122 764938 763358 orf19.13150|IPF12980.3|IPF13156.2|Contig4-3044_0016|orf6.4907|CA2843|ALK1|CaO19.5728|ALK5.5f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr6 767847 769811 + orf19.5729 767847 769811 1 767847 769811 767847 769811 FGR17 orf19.13151|IPF21450.1|IPF13158.2|Contig4-3044_0013|orf6.4908|CA2844|YNA2|CaO19.5729|CaO19.13151|IPF13158 Putative DNA-binding transcription factor; has zinc cluster DNA-binding motif; lacks an ortholog in S. cerevisiae; transposon mutation affects filamentous growth [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr6 769709 771703 - orf19.5730 769709 771703 1 771703 769709 771412 769871 orf19.13152|IPF21458.1|IPF10782.2|Contig4-3044_0011|orf6.4909|CA2845|CaO19.13152|CaO19.5730|IPF10782 Predicted ORF in Assemblies 19, 20 and 21; clade-associated gene expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 771822 772755 + orf19.5731 771822 772755 1 771822 772755 771996 772685 PAD1 orf19.13153|IPF21475.1|IPF10783.2|Contig4-3044_0010|orf6.4910|CA2846|CaO19.13153|CaO19.5731 Protein described as phenylacrylic acid decarboxylase; repressed by Rgt1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 772925 775304 + orf19.5732 772925 775304 2 772925|774401 773799|775304 772990 775192 NOG2 orf19.13154|orf19.13155|IPF21470.1|IPF10785.2|Contig4-3044_0008|Contig4-3044_0009|orf6.4911|orf6.4912|CA2847|orf19.5733|CA2848|IPF10785.exon2|IPF10786.2|IPF10785.exon1 Predicted ORF in Assemblies 19, 20 and 21; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 775244 776849 - orf19.5734 775244 776849 1 776849 775244 776769 775291 orf19.13156|IPF21459.1|IPF10787.2|Contig4-3044_0007|orf6.4913|CA2849|CaO19.13156|POP2|CaO19.5734 Putative protein of unknown function; heterozygous null mutant exhibits resistance to parnafungin and cordycepin in the C. albicans fitness test; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 776961 778322 - orf19.5735 776961 778322 1 778322 776961 778263 777073 CDC50 orf19.13157|IPF21465.1|IPF10789.2|Contig4-3044_0005|orf6.4914|CA2850|CaO19.5735 Predicted ORF in Assemblies 19, 20 and 21; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 779983 780732 - orf19.5735.3 779983 780732 1 780732 779983 780732 780436 IPF19628.1|CA2851|Tca5c ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr6 781739 781953 + ntar_1029 781739 781953 1 781739 781953 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 782055 782213 + ntar_1030 782055 782213 1 782055 782213 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 782616 786659 + orf19.5736 782616 786659 1 782616 786659 782616 786659 ALS5 orf19.13158|ALA1|ALS99|IPF21493.1|IPF19771.1|Contig4-2957_0018|Contig4-3044_0001|orf6.4915|CA2852|CaO19.5736 Adhesin; ALS family protein; highly variable; expression in S. cerevisiae causes adhesion to human epithelium, endothelium or ECM, endothelial invasiveness by endocytosis, and, at high abundance, ECM-induced aggregation; has amyloid domain [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr6 790740 795254 + orf19.5741 790740 795254 1 790740 795254 791472 795254 ALS1 orf19.13163|IPF21498.1|IPF13002.2|Contig4-2848_0008|orf6.1115|CA0316|CaO19.5741|ALS1.3eoc|IPF13002.1 Adhesin; ALS family of cell-surface glycoproteins; adhesion, virulence roles; immunoprotective; in band at hyphal base; amyloid domain; biofilm-induced; Rfg1p, Ssk1p, growth-regulated; strain background affects expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chr6 797443 803770 + orf19.5742 797443 803770 1 797443 803770 798023 803695 ALS9 orf19.13164|orf19.13168|IPF19916.1|IPF9917.1|IPF19856.2|IPF27935.1|IPF27926.1|Contig4-2858_0002|Contig4-2858_0004|orf6.2924|ALS9-1|ALS9-2|CA0315|CA1426|orf19.45|orf19.5745|ALS11|ALS9.5f|ALS9.5eoc|orf6.1114|IPF19856.1 ALS family protein; expressed during infection of human epithelial cells; confers laminin adhesion to S. cerevisiae; highly variable; ALS family includes cell-surface glycoproteins, some with adhesin function; putative GPI-anchor [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr6 803571 804137 - ntar_1031 803571 804137 1 804137 803571 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 804337 807368 + orf19.5746 804337 807368 1 804337 807368 804378 807287 ALA1 orf19.13169|IPF21506.1|IPF9914.1|Contig4-2858_0005|SYA1|orf6.2925|CA1427|CaO19.5746|CaO19.13169|IPF9914 Alanyl-tRNA synthetase; translational regulation generates cytoplasmic and mitochondrial forms; regulated by Gcn4p; repressed upon amino acid starvation (3-AT); translation-related genes downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 807311 808913 - orf19.5747 807311 808913 1 808913 807311 808842 807460 orf19.13170|IPF15124.2|IPF27934.1|Contig4-2858_0007|orf6.2926|CA1428|MRP4|CaO19.5747|CaO19.13170 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 809008 809909 + orf19.5748 809008 809909 1 809008 809909 809008 809625 orf19.13171|IPF15123.1|IPF18840.2|Contig4-2858_0008|orf6.2093|orf6.2927|CA1429|CaO19.5748|IPF15123 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr6 809441 810419 - orf19.5749 809441 810419 1 810419 809441 810326 809661 SBA1 orf19.13172|orf6.2092|IPF18677.2|IPF15122.2|Contig4-2858_0009|orf6.2928|CA0896|CaO19.5749 Similar to co-chaperones; transcriptionally regulated by iron; expression greater in high iron; farnesol-, heavy metal (cadmium) stress-induced; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 810631 812252 - orf19.5750 810631 812252 1 812252 810631 812212 810800 SHM2 orf19.13173|orf6.2091|SHMII|IPF21460.1|IPF15120.2|Contig4-2858_0010|CA0895|CaO19.5750|CaO19.13173 Cytoplasmic serine hydroxymethyltransferase; complements the glycine auxotrophy of an S. cerevisiae shm1 null shm2 null gly1-1 triple mutant; antigenic in human; soluble protein in hyphae; farnesol-upregulated in biofilm [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 813209 814483 - orf19.5751 813209 814483 1 814483 813209 814324 813518 ORM1 orf19.13174|IPF21473.1|IPF13514.2|Contig4-2419_0002|orf6.2090|CA0894|CaO19.13174|CaO19.5751 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to aureobasidin A [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 815149 817187 - orf19.5752 815149 817187 1 817187 815149 817145 815232 orf19.13175|IPF21451.1|IPF13517.3|Contig4-2419_0001|orf6.1417|orf6.2089|CA0893|CaO19.5752|IPF13517|IPF13517.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 817315 819351 - orf19.5753 817315 819351 1 819351 817315 819168 817528 HGT10 orf19.13176|orf6.1416|STL1|IPF19866.1|IPF27933.1|CA0472|CaO19.5753|CaO19.13176 Glycerol permease involved in glycerol uptake; member of the major facilitator superfamily; induced by osmotic stress, at low glucose in rich media, during cell wall regeneration; 12 membrane spans [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 822798 824769 - orf19.5754 822798 824769 1 824769 822798 824678 822828 orf19.13177|IPF18996.2|IPF17358.2|orf6.1301|orf6.1415|orf6.557|CA0112|CaO19.5754|IPF17358 Predicted ORF in Assemblies 19, 20 and 21; fluconazole-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 825402 825805 + ntar_1032 825402 825805 1 825402 825805 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 826572 828345 + orf19.5755 826572 828345 1 826572 828345 826857 828194 orf19.13178|IPF21462.1|IPF15067.1|Contig4-2302_0004|orf6.1302|CA0409|CaO19.13178|PHO80|CaO19.5755 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 828246 829290 - orf19.5757 828246 829290 1 829290 828246 829270 828320 orf19.13180|IPF15065.2|IPF27936.1|Contig4-2302_0005|orf6.1304|CA0410|CaO19.5757|CaO19.13180|IPF15065 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 830102 832226 + orf19.5758 830102 832226 1 830102 832226 830292 832007 SAL6 orf19.13181|IPF15064.3|IPF13917.1|Contig4-2302_0009|orf6.1305|orf6.6200|CA3829|CaO19.5758|PPQ1|CaO19.13181 Putative protein phosphatase of the Type 1 family (serine/threonine-specific), similar to S. cerevisiae Ppq1p; mutant shows virulence defect [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 832279 837058 - orf19.5759 832279 837058 1 837058 832279 836962 832475 SNQ2 orf19.13182|IPF21486.1|IPF13913.2|Contig4-3087_0024|orf6.6199|CA3828|CaO19.5759|CaO19.13182 Protein similar to S. cerevisiae Snq2p transporter; member of PDR subfamily of ABC family; transposon mutation affects filamentation; benomyl-induced transcription; detected at yeast-form cell plasma membrane by mass spec [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 837238 837548 - ntar_1033 837238 837548 1 837548 837238 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 838347 839747 - orf19.5760 838347 839747 1 839747 838347 839640 838462 IHD1 orf19.13183|PGA36|IPF21466.1|IPF10662.2|Contig4-2056_0002|orf6.6198|orf6.6197|YMR317|CA3827|orf19.5761|CaO19.13183|CaO19.5760|IPF10662 Putative GPI-anchored protein of unknown function; alkaline upregulated; greater transcription in hyphal form than yeast form; regulated by Nrg1p, Rfg1p, Tup1p; regulated by Tsa1p, Tsa1Bp in minimal media at 37; not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 841947 843131 - orf19.5762 841947 843131 1 843131 841947 842679 842008 PGA61 orf19.13185|IPF21476.1|IPF20148.1|Contig4-3026_0024|orf6.6196|CA3826|CaO19.5762|CaO19.13185|IPF20148 Putative GPI-anchored protein of unknown function; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 843289 843361 - ta(ugc)2 843289 843361 1 843361 843289 tA(UGC)2.2 tRNA-Ala predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 844100 845057 + orf19.5763 844100 845057 1 844100 845057 844153 844935 orf19.13186|IPF21472.1|IPF10654.2|Contig4-3026_0020|orf6.6195|CA3825|CaO19.13186|CaO19.5763|SPS19|IPF10654 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 844797 846175 - orf19.5764 844797 846175 1 846175 844797 846141 844987 SKI8 orf19.13187|IPF21468.1|IPF10653.2|Contig4-3026_0019|orf6.6194|CA3824|CaO19.5764|CaO19.13187 Protein similar to S. cerevisiae Ski8p, which is required for repressing propagation of dsRNA viruses [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 846289 848919 + orf19.5765 846289 848919 1 846289 848919 846348 848744 orf19.13188|IPF6983.2|IPF10651.2|Contig4-3026_0018|orf6.586|orf6.6193|CA3823|CaO19.5765|IPF10651 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 848640 849700 - orf19.5767 848640 849700 1 849700 848640 849610 848759 orf19.13190|IPF19836.1|IPF20001.1|Contig4-3026_0017|orf6.584|orf6.6191|CA3822|CUS2|CaO19.5767 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 849836 851007 + orf19.5768 849836 851007 1 849836 851007 849949 850959 SNF4 orf19.13191|IPF6988.2|IPF18292.1|IPF18293.1|Contig4-3026_0015|orf6.583|orf6.6189|orf6.6190|CA0122|CA6301|orf19.5769|SNF4.5f Protein similar to S. cerevisiae Snf4p transcriptional regulator; caspofungin repressed; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 851374 853572 + orf19.5770 851374 853572 1 851374 853572 851416 853572 OPT8 orf19.13192|IPF19226.2|IPF6990.2|Contig4-3026_0011|Contig4-3026_0013|orf6.582|orf6.6188|CA3821|CaO19.5770|IPF6990 Possible oligopeptide transporter; similar to Opt1p and to S. cerevisiae Ygl114wp, but not other OPTs; induced by nitric oxide, amphotericin B; expression of OPT6, -7, or -8 does not suppress defect of mutant lacking Opt1p, Opt2p, and Opt3p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr6 853702 855529 - orf19.5771 853702 855529 1 855529 853702 855456 853867 PBP2 orf19.13193|IPF21456.1|IPF6992.2|Contig4-3026_0010|orf6.6187|CA3820|CaO19.5771|CaO19.13193 Transcription is regulated by Nrg1p, Mig1p, and Tup1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 855664 856940 - orf19.5772 855664 856940 1 856940 855664 856798 855782 orf19.13194|IPF21469.1|IPF6993.1|Contig4-3026_0009|orf6.6186|CA3819|CaO19.13194|AOR1|CaO19.5772|IPF6993 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 857409 859891 + orf19.5773 857409 859891 1 857409 859891 857571 859673 orf19.13195|IPF21448.1|IPF6995.2|Contig4-3026_0008|orf6.6185|CA3818|CaO19.5773|CaO19.13195|IPF6695 Predicted ORF in Assemblies 19, 20 and 21; Hog1p-induced; clade-associated gene expression; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 863241 864779 - orf19.5775 863241 864779 1 864779 863241 864779 863241 orf19.13197|IPF21457.1|IPF20146.1|Contig4-2914_0008|orf6.6183|CA3817|CaO19.5775|CaO19.13197|IFV7 Predicted ORF in Assemblies 19, 20 and 21; member of a family encoded by FGR6-related genes in the RB2 repeat sequence [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 870878 871278 + ntar_1034 870878 871278 1 870878 871278 870878 871081 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 875330 875602 + ntar_1035 875330 875602 1 875330 875602 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 876166 876517 - ntar_1036 876166 876517 1 876517 876166 876517 876323 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 876329 877934 + orf19.1221 876329 877934 1 876329 877934 876484 877821 ALG2 orf19.8808|IPF26120.1|IPF9503.2|Contig4-2488_0004|orf6.3077|CA1530|CaO19.8808|CaO19.1221|ALG2.5 Putative mannosyltransferase involved in cell wall mannan biosynthesis; transcription is elevated in chk1, nik1, and sln1 homozygous null mutants [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 877840 879446 - orf19.1220 877840 879446 1 879446 877840 879364 878042 RVS167 orf19.8807|IPF26118.1|IPF9505.1|Contig4-2488_0001|orf6.3078|CA1531|CaO19.8807|CaO19.1220 Protein involved in endocytosis; contains a BAR domain; null mutant exhibits defects in hyphal growth, virulence, cell wall integrity, and actin patch localization; cosediments with phosphorylated Myo5p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 879750 881198 + orf19.1219 879750 881198 1 879750 881198 879846 881048 IPF29539.1|orf6.671|CA6186|CaO19.1219|IPF9507.5f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 881355 884467 + orf19.1217 881355 884467 1 881355 884467 881560 884196 orf19.8806|IPF9507.2|IPF16011.2|Contig4-2370_0009|orf6.669|orf6.3079|CA1532|CaO19.1217|IPF9507.3f|IPF9507 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 884297 885640 - orf19.1215 884297 885640 1 885640 884297 885640 884297 orf19.8803|IPF9510.2|IPF29538.1|Contig4-2370_0003|Contig4-2370_0004|orf6.3082|CA1533|CaO19.8803|CaO19.1215|IPF9510 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 884819 885217 + ntar_1037 884819 885217 1 884819 885217 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 885508 885737 + ntar_1038 885508 885737 1 885508 885737 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 886631 888187 + orf19.1214 886631 888187 1 886631 888187 886677 888020 orf19.8802|IPF26119.1|IPF9511.2|Contig4-2370_0007|orf6.3083|CA1534|MAP2|CaO19.8802|CaO19.1214 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 890075 891977 + orf19.1212 890075 891977 2 890075|890573 890275|891977 890242 891648 orf19.8800|IPF9515.2|IPF16581.1|Contig4-2317_0008|orf6.3085|orf6.845|CA1535|IPF9515 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 892498 894404 + orf19.1210 892498 894404 1 892498 894404 892798 894330 orf19.8799|IPF26117.1|IPF19126.1|orf6.843|CA0202|CaO19.1210|AVT5|CaO19.8799|IPF19126 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 892909 893178 - ntar_1039 892909 893178 1 893178 892909 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 893752 893962 - ntar_1040 893752 893962 1 893962 893752 893962 893792 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 894186 897962 - orf19.4557 894186 897962 1 897962 894186 897768 894484 orf19.8798|IPF26122.1|IPF19127.1|IPF15446.2|orf6.842|orf6.3076|CA1529|orf19.1209|SPC105.5eoc|SPC105 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr6 898674 904979 - orf19.4555 898674 904979 1 904979 898674 904976 898674 ALS4 IPF13009.2|IPF13010.2|IPF22626.1|IPF18130.1|ALS4.3f|Contig4-2046_0006|Contig4-2931_0006|orf6.3075|CA1527|CA1528|CA5173|orf19.4556|orf19.4610.1|ALS4.5f ALS family protein; role in adhesion and wild-type germ tube induction; growth and temperature regulated; expressed during infection of human buccal epithelial cells; down-regulated upon vaginal contact; putative GPI-anchored [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chr6 908141 910479 - orf19.4553 908141 910479 1 910479 908141 910392 908224 IPF13815.2|Contig4-2587_0013|orf6.3072|CA1526|CaO19.4553|IPF13815 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 910829 911276 - ntar_1041 910829 911276 1 911276 910829 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 911142 911295 + ntar_1042 911142 911295 1 911142 911295 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 911948 912199 + orf19.77.1 911948 912199 1 911948 912199 911948 912199 IPF27189.1|IPF29969.1 ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 912607 912819 + ntar_1043 912607 912819 1 912607 912819 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 913609 916361 - orf19.76 913609 916361 1 916361 913609 916324 913787 SPB1 orf19.7727|IPF19691.1|IPF13820.3|Contig4-2587_0002|orf6.1369|orf6.267|CA0443|CaO19.76 Predicted ORF in Assemblies 19, 20 and 21; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 916467 919609 - orf19.74 916467 919609 1 919609 916467 919494 916615 SEC5 orf19.7725|orf19.7726|IPF17429.2|IPF19821.2|IPF27187.1|IPF16249.2|orf6.1371|orf6.80|orf6.1370|CA0445|CA0444|orf19.75|CaO19.74|CaO19.7725|IPF17429.5f Predicted exocyst component; ortholog of S. cerevisiae Sec5p; merged with orf19.75 in Assembly 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr6 920270 923594 + orf19.73 920270 923594 1 920270 923594 920465 923449 orf19.7724|IPF17657.3|IPF17430.1|orf6.22|orf6.1372|orf6.79|CA0011|orf19.62|CaO19.73|IPF17430.5eoc|IPF17430 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 923732 924998 - orf19.1075 923732 924998 1 924998 923732 924998 923865 IPF18831.2|IPF19160.1|Contig4-1626_0009|orf6.735|CA0167|CaO19.1075|IPF19160 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr6 923850 924737 + ntar_1044 923850 924737 1 923850 924737 924086 924217 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 926802 927073 + ntar_1045 926802 927073 1 926802 927073 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 926947 927920 - orf19.1075.1 926947 927920 1 927920 926947 927239 927111 Pseudogene; added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr6 928126 930738 - orf19.1077 928126 930738 1 930738 928126 930521 928269 ATM1 orf19.8678|orf19.8676|orf6.2145|orf6.736|IPF14199.2|IPF19157.2|Contig4-2068_0003|orf6.2147|CA0933|CaO19.1077 Member of MDR subfamily of ABC family; similar to S. cerevisiae ABC transporter, Atm1p; transcriptionally regulated by iron; expression greater in low iron; induced by nitric oxide in yhb1 mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 931038 932559 - orf19.1078 931038 932559 1 932559 931038 932489 931212 HBR2 orf19.8679|orf19.8680|IPF26229.1|IPF26228.1|IPF14203.2|IPF14202.2|Contig4-2068_0002|orf6.2148|orf6.2149|CA0934|CA0935|orf19.1079|IPF14203.3f Uncharacterized protein, regulated by Gcn4p and hemoglobin; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 934133 935740 + orf19.1080 934133 935740 1 934133 935740 934133 935740 orf19.8681|IPF26225.1|IPF16291.2|Contig4-1486_0005|orf6.2150|CA0936|IPF16291 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr6 934341 934769 - ntar_1046 934341 934769 1 934769 934341 934769 934437 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 934803 935140 - ntar_1047 934803 935140 1 935140 934803 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 936156 936932 + orf19.1082 936156 936932 1 936156 936932 936223 936738 orf19.8683|orf6.1531|orf6.2152|CA0937|CaO19.1082|IPF19892|IPF19892.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 936556 936882 - ntar_1048 936556 936882 1 936882 936556 936821 936648 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 937012 938127 + orf19.1082.1 937012 938127 1 937012 938127 937165 937416 IPF16288.3|IPF16287.1|Contig4-2123_0001|CA0938|COX12|IPF16288.2 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 937700 938473 - orf19.1083 937700 938473 1 938473 937700 938440 937757 orf19.8684|IPF26227.1|IPF14574.2|Contig4-2123_0002|orf6.1532|CA0541|CaO19.8684|CaO19.1083|IPF14574 Predicted ORF in Assemblies 19, 20 and 21; macrophage-induced gene; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 938969 946262 + orf19.1084 938969 946262 1 938969 946262 940096 946146 CDC39 orf19.8685|IPF19634.2|IPF19633.2|Contig4-2123_0005|orf6.1517|orf6.1533|CA0542|CaO19.1084|CA0530|IPF19633.3eoc|IPF19634.1 Protein similar to S. cerevisiae Cdc39p, which is part of the CCR4-NOT transcription regulatory complex; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 946606 947885 + orf19.1085 946606 947885 1 946606 947885 946663 947361 orf19.8686|IPF10066.2|IPF17337.1|Contig4-2194_0002|Contig4-2887_0017|orf6.1226|orf6.1518|CA0531|UBC1|CaO19.1085 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 948102 950448 + orf19.1086 948102 950448 1 948102 950448 948405 950273 orf19.8687|IPF19327.2|IPF10062.2|Contig4-2194_0004|orf6.1225|orf6.349|CA0372|BRE5|CaO19.1086|IPF10062 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 950690 953206 + orf19.1087 950690 953206 1 950690 953206 950706 953156 orf19.8688|IPF19579.1|IPF19578.1|orf6.1224|orf6.350|CA0371|CaO19.1087|IPF19578 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=G scenario_last_exon=G] Ca21chr6 953484 954703 + orf19.1089 953484 954703 1 953484 954703 953697 954434 PEX11 orf19.8690|IPF19049.2|IPF29582.1|orf6.1103|orf6.1222|CA0310|CaO19.1089|IPF19049.1 Putative protein involved in fatty acid oxidation; expression is Tac1p-dependent [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 954533 955034 - orf19.1090 954533 955034 1 955034 954533 954968 954621 orf19.8691|IPF26232.1|IPF16934.2|orf6.1102|CaO19.8691|CaO19.1090 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 955096 957398 + orf19.1091 955096 957398 1 955096 957398 955195 957267 orf19.8692|IPF26223.1|IPF16935.2|orf6.1101|CA0309|CaO19.8692|NOP8|CaO19.1091|IPF16935 Putative ortholog of S. cerevisiae Nop8p, which is a nucleolar protein required for 60S ribosomal subunit biogenesis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 957538 959407 + orf19.1092 957538 959407 1 957538 959407 957611 959170 orf19.8693|IPF17442.2|IPF29580.1|orf6.1100|CA0308|RHK1|CaO19.1092 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 959308 963095 - orf19.1093 959308 963095 1 963095 959308 962260 959807 FLO8 orf19.8695|IPF26221.1|IPF10214.2|orf6.3004|CA1476|CaO19.1093|IPF10214 Transcription factor; required for wild-type hyphal formation; regulates hyphal gene expression; required for virulence in mouse systemic infection; binds Efg1p; binds Mss11p via LisH motif; has LUFS domain; ortholog of S. cerevisiae Flo8p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr6 964403 965911 - orf19.1095 964403 965911 1 965911 964403 965793 964642 orf19.8697|IPF26226.1|IPF10209.2|Contig4-2338_0010|orf6.3002|CA1475|CaO19.1095|GLE2|CaO19.8697 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 965993 968817 + orf19.1096 965993 968817 1 965993 968817 966081 968720 orf19.8698|IPF26218.1|IPF10208.2|Contig4-2338_0007|orf6.3001|CA1474|CaO19.8698|GEF13|CaO19.1096|IPF10208 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 970509 970725 - ntar_1049 970509 970725 1 970725 970509 970725 970597 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 970928 978542 + orf19.1097 970928 978542 1 970928 978542 971454 978542 ALS2 orf19.8699|orf19.8700|orf19.9669|orf19.9670|orf6.1311|ALS4|IPF26222.1|IPF26230.1|IPF15450.3|IPF10205.2|IPF25194.1|IPF25217.1|IPF18994.1|IPF16055.3|orf6.3000|orf6.2999|CA1473|CA1471|CA0412|CA0413|orf19.1098|orf19.2121|orf19.2122|ALS12|ALS2.5f ALS family protein; role in adhesion, biofilm formation, germ tube induction; expressed at infection of human buccal epithelial cells; putative GPI-anchor; induced by ketoconazole, low iron and at cell wall regeneration; regulated by Sfu1p [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr6 978569 979045 + ntar_1050 978569 979045 1 978569 979045 978569 979045 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 983993 985862 - orf19.2124 983993 985862 1 985862 983993 985627 984557 orf19.9672|IPF16259.1|IPF29191.1|IPF29204.1|Contig4-1838_0002|orf6.863|CA6197|IFR5.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 986080 986650 + orf19.2125 986080 986650 1 986080 986650 986080 986535 IPF16257.1|IPF29197.1|Contig4-1838_0003|orf6.864|CaO19.2125 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr6 987862 989073 + orf19.2127 987862 989073 1 987862 989073 987902 989053 orf19.9674|IPF25189.1|IPF16108.2|Contig4-1925_0003|orf6.5360|orf6.5361|orf19.2126|CaO19.2127 Predicted ORF in Assemblies 19, 20 and 21; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr6 988823 991538 - orf19.2129 988823 991538 1 991538 988823 991538 989037 orf19.9676|IPF25177.1|IPF19786.1|Contig4-1925_0002|Contig4-1925_0005|orf6.5363|SPO71|CaO19.9676|CaO19.2129 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr6 991540 992740 + orf19.2128 991540 992740 1 991540 992740 991541 992731 orf19.9675|IPF25188.1|IPF12246.2|Contig4-2687_0001|orf6.5362|CA3179|CaO19.2128|CaO19.9675|YLF2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 992934 993048 + tl(caa)3 992934 993048 2 992934|993005 992972|993048 tL(CAA)3.2 tRNA-Leu predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 993052 995492 - orf19.2131 993052 995492 1 995492 993052 995441 993111 orf19.9678|IPF25179.1|IPF12244.2|Contig4-2687_0002|orf6.5365|CA3180|CaO19.9678|CaO19.2131|IPF12244 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 995517 996289 - orf19.2132 995517 996289 1 996289 995517 996225 995524 orf19.9679|IPF25191.1|IPF12241.1|Contig4-2687_0003|orf6.5366|CA3181|CaO19.9679|CaO19.2132|IPF12241 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 997381 1003738 - orf19.2135 997381 1003738 1 1003738 997381 1003738 999461 TSM1 orf19.9682|orf19.9683|IPF25185.1|IPF25176.1|IPF13636.2|IPF15656.2|orf6.287|orf6.5369|orf6.5370|CA3183|CA3184|orf19.2136|TSM1.3f Putative protein of unknown function, transcription is upregulated in clinical isolates from HIV+ patients with oral candidiasis; transcription is regulated by Nrg1p; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 998012 999391 + orf19.2133 998012 999391 1 998012 999391 998012 999391 LIP4 orf19.9680|IPF19830.2|IPF15657.2|Contig4-2687_0005|orf6.288|orf6.5367|CA3182|CaO19.2133 Secreted lipase, member of a differentially expressed lipase gene family with possible roles in nutrition and/or in creating an acidic microenvironment; expressed more strongly during mucosal infections than during systemic infections [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr6 1003757 1005342 - orf19.2137 1003757 1005342 1 1005342 1003757 1005292 1003841 orf19.9684|IPF25186.1|IPF13637.2|Contig4-2481_0005|orf6.5371|CA3185|CaO19.9684|CaO19.2137|IPF13637 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 1005432 1008759 + orf19.2138 1005432 1008759 1 1005432 1008759 1005464 1008730 ILS1 orf19.9685|IPF25214.1|IPF13644.2|Contig4-2481_0004|orf6.5372|CA3186|CaO19.2138|CaO19.9685 Protein similar to isoleucyl-tRNA synthetase, the target of drugs including the cyclic beta-amino acid icofungipen/PLD-118/BAY-10-8888 and mupirocin; detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 1008616 1011589 - orf19.2143 1008616 1011589 1 1011589 1008616 1011582 1008739 orf19.9690|IPF25218.1|IPF17094.2|Contig4-2481_0003|orf6.5377|CA3187|CaO19.9690|CaO19.2143|IPF17094 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 1011720 1011955 + ntar_1051 1011720 1011955 1 1011720 1011955 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr6 1012058 1013425 - orf19.2146 1012058 1013425 1 1013425 1012058 1013409 1012261 orf19.9693|IPF25187.1|IPF11610.2|Contig4-2303_0002|orf6.5380|CA3188|HAT2|CaO19.2146|IPF11610 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 1013470 1015794 - orf19.2149 1013470 1015794 1 1015794 1013470 1015748 1013475 orf19.9696|IPF25180.1|IPF11607.2|Contig4-2303_0004|orf6.5383|CA3189|CaO19.9696|CaO19.2149|IPF11607 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 1015894 1016950 + orf19.2150 1015894 1016950 1 1015894 1016950 1015905 1016894 orf19.9697|IPF25190.1|IPF11603.2|Contig4-2063_0006|Contig4-2303_0006|orf6.5384|CA3190|CaO19.9697|CaO19.2150|IPF11603 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 1016974 1019424 + orf19.2151 1016974 1019424 1 1016974 1019424 1016993 1019365 NAG6 orf19.9698|IPF25181.1|IPF11601.2|Contig4-2063_0005|orf6.5385|SEY1|CA3191|CaO19.2151|CaO19.9698|IPF11601 Protein required for wild-type mouse virulence and wild-type cycloheximide resistance; putative GTP-binding motif; similar to S. cerevisiae Yor165Wp; in gene cluster that encodes enzymes of GlcNAc catabolism; no human or murine homolog [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 1019506 1021076 + orf19.2154 1019506 1021076 1 1019506 1021076 1019511 1020992 HXK1 orf19.9701|NAG5|IPF2721.2|IPF11598.2|Contig4-2021_0003|Contig4-2063_0001|Contig4-2063_0004|orf6.2468|orf6.5388|CA3192|CaO19.2154|IPF11598 N-acetylglucosamine (GlcNAc) kinase; involved in GlcNAc utilization; required for wild-type hyphal growth and mouse virulence; gene expression is GlcNAc-induced; induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr6 1021185 1022030 - orf19.2156 1021185 1022030 1 1022030 1021185 1021981 1021235 NAG1 orf19.9703|IPF2719.1|IPF29192.1|Contig4-2021_0001|orf6.5390|orf6.2470|CA1130|CaO19.2156 Glucosamine-6-phosphate deaminase; enzyme of N-acetylglucosamine utilization; required for wild-type hyphal growth and mouse virulence; converts glucosamine 6-P to fructose 6-P; reaction is reversible in vitro; gene is GlcNAc-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 1022157 1023509 + orf19.2157 1022157 1023509 1 1022157 1023509 1022223 1023464 DAC1 orf19.9704|NAG2|IPF20073.1|IPF20045.2|Contig4-2021_0002|orf6.2471|orf6.684|CA1131|CaO19.2157 N-acetylglucosamine-6-phosphate (GlcNAcP) deacetylase; enzyme of N-acetylglucosamine utilization; required for wild-type hyphal growth and virulence in mouse systemic infection; gene is GlcNAc-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 1023375 1025223 - orf19.2158 1023375 1025223 1 1025223 1023375 1025158 1023473 NAG3 orf6.683|MDR97|orf6.682|TMP1|IPF2706.2|IPF2714.2|Contig4-2515_0003|orf6.2472|CA6268|CA1132|orf19.2159|IFY2.3f Putative transporter of the major facilitator superfamily (MFS); similar to Nag4p; required for wild-type mouse virulence and cycloheximide resistance; in gene cluster that includes genes encoding enzymes of GlcNAc catabolism [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr6 1025368 1027113 - orf19.2160 1025368 1027113 1 1027113 1025368 1027113 1025368 NAG4 orf19.9706|TMP2|IPF2710.1|IPF2708.3|Contig4-2515_0002|orf6.2473|orf6.681|CA1133|GAN4|CaO19.2160|IFY1|IPF2710.repeat1 Putative transporter; fungal-specific; similar to Nag3p and to S. cerevisiae Ypr156Cp and Ygr138Cp; required for wild-type mouse virulence and wild-type cycloheximide resistance; gene cluster encodes enzymes of GlcNAc catabolism [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr6 1028782 1031331 + orf19.2163 1028782 1031331 1 1028782 1031331 1028818 1031331 orf19.9709|IPF25178.1|IPF2702.1|orf6.2476|CA1134|CaO19.2163|CaO19.9709|IPF2702 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr7 50 1159 - orf19.7125 50 1159 1 1159 50 1155 97 IPF5661.2|Contig4-2995_0002|orf6.8428|CA5579|CaJ7.0001|CaO19.7125|CaO19_7125|CaJ7_0001|IPF5661|IPF5661.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 1189 2050 - orf19.7124 1189 2050 1 2050 1189 2040 1246 RVS161 IPF5657.1|Contig4-2995_0004|orf6.8429|CA5580|CaJ7.0003|CaO19.7124 Protein required for endocytosis; contains a BAR domain, which is found in proteins involved in membrane curvature; null mutant exhibits defects in hyphal growth, virulence, cell wall integrity, and actin patch localization [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 2124 2921 + orf19.7123 2124 2921 1 2124 2921 2278 2769 IPF5653.1|Contig4-2995_0005|orf6.8430|CaJ7.0004|CaO19.7123|CaO19_7123|CaJ7_0004 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 2398 3428 - orf19.7121 2398 3428 1 3428 2398 3421 2747 IPF5652.1|Contig4-2995_0006|orf6.8432|CaJ7.0005|CaO19.7121|CaO19_7121|CaJ7_0005 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 3453 5761 - orf19.7119 3453 5761 1 5761 3453 5761 3464 IPF5649.1|Contig4-2995_0008|orf6.8434|CA5581|CaJ7.0007|RAD3|CaO19.7119|CaJ7_0007|CaO19_7119 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 5799 6467 - orf19.7118 5799 6467 1 6467 5799 6467 5799 IPF5646.1|Contig4-2995_0009|orf6.8435|CA5582|CaJ7.0009|CaO19_7118|CaJ7_0009|CaO19.7118|ADK2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 6523 7476 - orf19.7116 6523 7476 1 7476 6523 7476 6523 IPF5644.1|Contig4-2995_0012|orf6.8437|CA5583|CaJ7.0011|CaO19.7116|CaO19_7116|CaJ7_0011|IPF5644 Putative protein of unknown function, transcription is upregulated in an RHE model of oral candidiasis; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 7548 9430 - orf19.7115 7548 9430 1 9430 7548 9430 7583 SAC7 IPF5642.1|Contig4-2995_0014|orf6.8438|CA5584|CaJ7.0013|CaO19.7115 Protein described as a GTPase activating protein (GAP) for RHO1; downregulated upon adherence to polystyrene; macrophage/pseudohyphal-repressed; transcription is upregulated in RHE model of oral candidiasis and in clinical oral candidiasis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 9933 13341 - orf19.7114 9933 13341 1 13341 9933 13080 10024 CSA1 orf6.8439|WAP1|IPF5641.1|Contig4-2995_0015|CA5585|CaJ7.0015|CaO19_7114|CaJ7_0015|CaO19.7114 Surface antigen on elongating hyphae and buds; no obvious hyphal defects in mutant; strain variation in number of repeat domains; upregulated in filaments; alkaline upregulated by Rim101p; ciclopirox induced; Efg1p- and Cph1p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr7 14047 15866 + orf19.7112 14047 15866 1 14047 15866 14047 15825 FRP2 IPF5625.1|Contig4-2995_0020|orf6.8441|CA5586|CaJ7.0017|CaO19.7112|CaO19_7112|CaJ7_0017|IPF5625 Protein described as ferric reductase; alkaline upregulated by Rim101p; fluconazole-downregulated; upregulated in the presence of human neutrophils; possibly adherence-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 15973 16662 + orf19.7111.1 15973 16662 2 15973|16147 16086|16662 15982 16662 SOD3 SOD21|IPF5623.1|IPF5622.1|Contig4-2995_0021|CA5587|CaJ7.0018|SOD22|orf19.7111.2|CaJ7_0018|CA5588|SOD22.3f Cytosolic manganese-containing superoxide dismutase, involved in protection against oxidative stress; transcription downregulated by treatment with ciclopirox olamine, induced during stationary phase when SOD1 expression is repressed [label_first_exon=CGDmod label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 16071 16467 - ntar_1052 16071 16467 1 16467 16071 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 16744 17208 + orf19.7111 16744 17208 1 16744 17208 16744 17208 IPF5621.1|Contig4-2995_0022|orf6.8442|CA5589|CaJ7.0019|CaO19.7111|FIS1|CaJ7_0019|CaO19_7111|IPF5621 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 17244 18340 + orf19.7110 17244 18340 1 17244 18340 17255 18298 IPF5619.1|Contig4-2995_0023|orf6.8443|CA5590|CaJ7.0020|CaO19_7110|CaJ7_0020|CaO19.7110|TAD1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 18163 18970 - orf19.7109 18163 18970 1 18970 18163 18851 18321 IPF5618.1|Contig4-2995_0024|orf6.8444|CA5591|CaJ7.0021|CaO19.7109|CaJ7_0021|CaO19_7109|IPF5618 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 19067 19988 + orf19.7108 19067 19988 1 19067 19988 19179 19871 IPF5616.1|Contig4-2995_0027|orf6.8445|CA5592|CaJ7.0022|CaO19.7108|RPE1|CaJ7_0022|CaO19_7108 Predicted ORF in Assemblies 19, 20 and 21; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 19877 20366 - orf19.7107 19877 20366 1 20366 19877 20349 19888 IPF5615.1|Contig4-2995_0028|orf6.8446|CA5593|CaJ7.0023|CaO19_7107|CaJ7_0023|CaO19.7107|IPF5615 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 21062 23531 + orf19.7106 21062 23531 1 21062 23531 21072 23375 IPF19814.1|Contig4-3106_0075|orf6.8447|CA5594|CaJ7.0024|CaO19.7106|CaO19_7106|CaJ7_0024|IPF19814 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 23536 25876 + orf19.7105 23536 25876 1 23536 25876 23536 25842 FAR1 IPF568.2|Contig4-3106_0001|Contig4-3106_0003|orf6.8448|CA5595|CaJ7.0025|CaO19_7105|CaJ7_0025|CaO19.7105|IPF568 Protein involved in regulation of pheromone-mediated mating; repressed by A1p and Alpha2p in white-phase cells; null mutant shows no pheromone response in opaque cells; overexpression causes enhanced pheromone response and cell cycle arrest [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr7 25560 25876 - ntar_1053 25560 25876 1 25876 25560 25876 25661 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 25936 27089 + orf19.7104 25936 27089 1 25936 27089 26062 27036 IPF564.2|Contig4-3106_0005|orf6.8449|CA5596|CaJ7.0026|CaO19.7104|CaO19_7104|CaJ7_0026|IPF564 Predicted ORF in Assemblies 19, 20 and 21; similar to mucins and to a Litomosoides microfilarial sheath protein [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 27104 28348 + orf19.7103 27104 28348 1 27104 28348 27138 28232 IPF563.1|Contig4-3106_0006|orf6.8450|CA5597|CaJ7.0027|CaO19_7103|CaJ7_0027|CaO19.7103|IPF563 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 28096 30600 - orf19.7101 28096 30600 1 30600 28096 30591 28225 IPF562.1|Contig4-3106_0008|orf6.8452|CA5598|CaJ7.0029|CaO19_7102|CaJ7_0028|CaO19.7101|TEL2|IPF562 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 30551 31618 + orf19.7102 30551 31618 1 30551 31618 30551 31618 IPF560.1|Contig4-3106_0009|orf6.8451|CA5599|CaJ7.0028|CaO19.7102|IPF560 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 31779 33545 + orf19.7100 31779 33545 1 31779 33545 31779 33545 IPF559.1|Contig4-3106_0010|Contig4-3106_0011|orf6.8453|CA5600|CaJ7.0030|AVT11|CaO19.7100|CaO19_7100|CaJ7_0030|IPF559 Predicted ORF in Assemblies 19, 20 and 21; possibly transcriptionally regulated upon hyphal formation [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 33631 34149 - ntar_1054 33631 34149 1 34149 33631 34122 33922 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 33810 34524 + orf19.7098 33810 34524 1 33810 34524 33810 34454 IPF556.1|Contig4-3106_0013|orf6.8455|CA5601|CaJ7.0032|CaO19.7098|CaJ7_0032|CaO19_7098|IPF556 Predicted ORF in Assemblies 19, 20 and 21; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 34254 35230 - orf19.7097 34254 35230 1 35230 34254 35195 34632 IPF554.1|Contig4-3106_0014|orf6.8456|CA5602|CaJ7.0033|CaO19_7097|CaJ7_0033|CaO19.7097|SGN12|IPF554 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 35315 38330 - orf19.7096 35315 38330 1 38330 35315 38295 35365 IPF553.1|Contig4-3106_0015|orf6.8457|CA5603|CaJ7.0034|CaO19_7096|CaJ7_0034|CaO19.7096|IPF553 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 38480 40137 + orf19.7095 38480 40137 1 38480 40137 38507 39679 IPF549.1|Contig4-3106_0019|orf6.8458|CA5604|CaJ7.0035|CaO19_7095|CaJ7_0035|CaO19.7095|IPF549 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 41503 43167 + orf19.7094 41503 43167 1 41503 43167 41587 43167 HGT12 RGT2|IPF546.1|GS|CG13|Contig4-3106_0021|orf6.8459|CA5605|CaJ7.0036|SNF32|CaO19.7094|CaO19_7094|CaJ7_0036|SNF31 Glucose, fructose, mannose transporter; major facilitator superfamily; role in macrophage-induced hyphal growth; detected at germ tube plasma membrane by mass spectrometry; Snf3p-induced; 12 probable transmembrane segments [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chr7 43379 45240 - orf19.7093 43379 45240 2 45240|43651 43717|43379 45102 43379 HGT13 STL1|IPF541.2|IPF542.2|Contig4-3106_0022|Contig4-3106_0023|orf6.8460|STL2|CA5606|CaJ7.0038|orf19.7093.2|CaO19_7093|CaJ7_0038|CA5607|STL2.5f|STL2.3f Predicted sugar transporter, involved in glycerol utilization; member of the major facilitator superfamily; 12 transmembrane; gene has intron; oxidative stress-induced via Cap1p; expressed in rich medium, 2% glucose [label_first_exon=CGDmod label_last_exon=CGD orf_changed=false scenario_first_exon=H scenario_last_exon=C] Ca21chr7 46290 47270 + orf19.7092 46290 47270 1 46290 47270 46309 47109 IPF539.1|Contig4-3106_0025|orf6.8461|CA5608|CaJ7.0039|CaO19_7092|CaJ7_0039|CaO19.7092|IPF539 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 47106 48074 - orf19.7091 47106 48074 1 48074 47106 47988 47152 IPF538.1|Contig4-3106_0026|orf6.8462|CA5609|CaJ7.0041|CaO19.7091|CaJ7_0041|CaO19_7091|IPF538 Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 48271 51267 - orf19.7089 48271 51267 1 51267 48271 51214 48461 PMR1 IPF534.2|Contig4-3106_0029|Contig4-3106_0030|orf6.8464|CA5610|CaJ7.0043|CaO19_7089|CaJ7_0043|CaO19.7089 Putative secretory pathway P-type Ca2+/Mn2+-ATPase; required for protein glycosylation and cell wall maintenance; required for hyphal tip oscillation in semisolid substrate; putative ortholog of S. cerevisiae PMR1 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 51533 52864 - orf19.7088 51533 52864 1 52864 51533 52855 51707 IPF529.1|Contig4-3106_0032|orf6.8465|CA5611|CaJ7.0044|CaO19.7088|SUA5|CaJ7_0044|CaO19_7088 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 52894 55888 - orf19.7086 52894 55888 1 55888 52894 55866 52951 IPF527.1|Contig4-3106_0034|orf6.8467|CA5612|CaJ7.0045|KAP114|CaO19.7086|CaJ7_0045|CaO19_7086 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 56026 57417 - orf19.7085 56026 57417 1 57417 56026 57377 56058 IPF525.1|Contig4-3106_0036|orf6.8468|CA5613|CaJ7.0047|CaO19.7085|CaJ7_0047|CaO19_7085|IPF525 Predicted ORF in Assemblies 19, 20 and 21; induced in core stress response; induced by heavy metal (cadmium) stress via Hog1p; oxidative stress-induced via Cap1p; induced by Mnl1p under weak acid stress; macrophage-downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 58868 60202 + orf19.7084 58868 60202 1 58868 60202 59071 60084 DFI1|IPF522.1|Contig4-3106_0042|orf6.8469|CA5614|CaJ7.0048|CaO19.7084|CaJ7_0048|CaO19_7084|IPF522 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 60278 61357 + orf19.7083 60278 61357 1 60278 61357 60279 61298 DCC1 IPF520.1|Contig4-3106_0044|orf6.8470|CA5615|CaJ7.0049|CaO19_7083|CaJ7_0049|CaO19.7083|IPF520 Predicted ORF in Assemblies 19, 20 and 21; cell-cycle regulated periodic mRNA expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 61416 62319 + orf19.7082 61416 62319 1 61416 62319 61437 62255 IPF519.1|Contig4-3106_0045|orf6.8471|CA5616|CaJ7.0050|CaO19_7082|CaJ7_0050|CaO19.7082|PET8 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 62460 64022 + orf19.7081 62460 64022 1 62460 64022 62478 63944 SPL1 orf6.8472|NFS1|IPF518.1|Contig4-3106_0046|CA5617|CaJ7.0052|CaO19_7081|CaJ7_0052|CaO19.7081 Protein similar to S. cerevisiae Spl1p, which is involved in tRNA splicing; member of pyridoxal-phosphate-dependent aminotransferase protein family; predicted to be essential [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 64158 65279 + orf19.7080 64158 65279 1 64158 65279 64158 65279 LEU2 IPF516.1|Contig4-3106_0047|orf6.8473|CA5618|CaJ7.0053|CaJ7_0053|CaO19_7080|CaO19.7080 Isopropyl malate dehydrogenase; enzyme of leucine biosynthesis; upregulated in the presence of human whole blood or polymorphonuclear (PMN) cells; protein level decreased in stationary phase cultures [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr7 65280 68766 - orf19.7079 65280 68766 1 68766 65280 68746 65303 IPF514.1|Contig4-3106_0049|orf6.8474|CA5619|CaJ7.0054|BUD3|CaO19.7079|CaJ7_0054|CaO19_7079|IPF514 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 68937 69570 - orf19.7078 68937 69570 1 69570 68937 69539 69078 IPF511.1|Contig4-3106_0051|orf6.8475|CA5620|CaJ7.0055|CaO19.7078|CaJ7_0055|CaO19_7078|IPF511 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 69196 69388 + ntar_1055 69196 69388 1 69196 69388 69196 69339 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 70546 72453 + orf19.7077 70546 72453 1 70546 72453 70601 72361 orf6.8476|IPF507.2|FRE7|Contig4-3106_0052|Contig4-3106_0053|CA5621|CaJ7.0056|CaO19.7077|CaO19_7077|CaJ7_0056 Protein with similarity to ferric reductases; transcription is activated by Mac1p under copper starvation; Plc1p-regulated; transcription is negatively regulated by Rim101p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 72345 74467 - orf19.7076 72345 74467 2 74467|73935 74300|72345 74332 72658 IPF506.1|Contig4-3106_0055|orf6.8477|CA5622|CaJ7.0058|GBP2.3f|GBP2.3 Predicted ORF in Assemblies 19, 20 and 21; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 74638 75480 - orf19.7074 74638 75480 1 75480 74638 75454 74657 IPF502.1|Contig4-3106_0058|orf6.8479|CA5623|CaJ7.0059|CaO19_7074|CaJ7_0059|CaO19.7074|IPF502 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 75345 76342 + orf19.7073 75345 76342 1 75345 76342 75620 76342 IPF501.1|Contig4-3106_0061|orf6.8480|CA5624|CaJ7.0060|CaO19_7073|CaJ7_0060|CaO19.7073|IPF501 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr7 76252 77996 - orf19.7072 76252 77996 1 77996 76252 77930 76425 PEL1 IPF499.1|Contig4-3106_0062|orf6.8481|CA5625|CaJ7.0061|CaJ7_0061|CaO19_7072|PGS1|CaO19.7072 Predicted enzyme of mitochondrial phospholipid biosynthesis; upregulated in biofilm [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 79434 81007 + orf19.7071 79434 81007 1 79434 81007 79446 80990 FGR2 PHO84|IPF498.1|Contig4-3106_0064|orf6.8482|CA5626|CaJ7.0062|CaO19.7071|CaO19_7071|CaJ7_0062|IPF498 Protein similar to phosphate transporters; transposon mutation affects filamentous growth; expression is regulated upon white-opaque switching [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 81011 82115 - orf19.7069 81011 82115 1 82115 81011 81905 81174 IPF495.1|Contig4-3106_0065|orf6.8484|CA5627|CaJ7.0064|CaO19_7069|CaJ7_0064|CaO19.7069|IPF495 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 81346 81816 + orf19.7070 81346 81816 1 81346 81816 81346 81816 IPF496.1|orf6.8483 [NOT TRANSCRIBED?] ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 82504 83951 + orf19.7068 82504 83951 1 82504 83951 82584 83879 MAC1 IPF492.1|Contig4-3106_0066|orf6.8485|CA5628|CaJ7.0065|CaJ7_0065|CaO19_7068|CaO19.7068 Transcriptional regulator of CTR1, which encodes a copper transporter; activates CTR1 transcription under low-copper conditions; ectopic expression causes copper-sensitive stimulation of filamentation in S. cerevisiae [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 84133 87648 + orf19.7067 84133 87648 1 84133 87648 84177 87452 IPF489.1|Contig4-3106_0067|orf6.8486|CA5629|CaJ7.0066|CaO19_7067|CaJ7_0066|CTR9|CaO19.7067 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 87554 88156 - orf19.7065 87554 88156 1 88156 87554 88111 87578 PSF3 IPF486.2|Contig4-3106_0069|orf6.8488|CA5630|CaJ7.0068|CaO19_7065|CaJ7_0068|CaO19.7065|IPF486 Predicted ORF in Assemblies 19, 20 and 21; cell-cycle regulated periodic mRNA expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 88559 91108 - orf19.7064 88559 91108 1 91108 88559 91080 88681 GLN4 IPF485.2|Contig4-3106_0070|Contig4-3106_0071|GLN4A|orf6.8489|CA5631|CaJ7.0069|CaO19.7064|CaO19_7064|CaJ7_0069 Putative tRNA-Gln synthetase; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 91292 92165 - orf19.7063 91292 92165 1 92165 91292 92165 91359 IPF480.2|Contig4-3106_0072|orf6.8490|CA5632|CaJ7.0070|CaJ7_0070|CaO19_7063|CaO19.7063|THG1|IPF480 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 92353 95994 + orf19.7062 92353 95994 1 92353 95994 92423 95923 RPA135 IPF479.1|Contig4-3106_0073|orf6.8491|CA5633|CaJ7.0071|CaO19.7062|CaJ7_0071|CaO19_7062 Predicted ORF in Assemblies 19, 20 and 21; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 95931 96742 - orf19.7061 95931 96742 1 96742 95931 96723 96043 IPF477.1|orf6.8492|CA5634|CaJ7.0072|CaO19_7061|CaJ7_0072|CaO19.7061|IPF477 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 96244 98019 + orf19.7060 96244 98019 1 96244 98019 96928 97902 IPF474.1|Contig4-2959_0002|orf6.8493|CA5635|CaJ7.0073|CaO19.7060|CaO19_7060|CaJ7_0073|IPF474 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 97873 99315 - orf19.7059 97873 99315 1 99315 97873 99298 97943 IPF473.1|Contig4-2959_0003|orf6.8494|CA5636|CaJ7.0074|CaO19.7059|CaJ7_0074|CaO19_7059|IPF473 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 99537 101387 - orf19.7058 99537 101387 1 101387 99537 101327 99537 IPF472.1|Contig4-2959_0004|orf6.8495|CA5637|CaJ7.0075|CaO19.7058|CaO19_7058|CaJ7_0075|IPF472 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 101568 103930 + orf19.7057 101568 103930 1 101568 103930 101629 103806 IPF470.1|Contig4-2959_0005|orf6.8496|CA5638|CaJ7.0076|CaO19_7057|CaJ7_0076|CaO19.7057|IPF470 Predicted ORF in Assemblies 19, 20 and 21; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 103919 105906 - orf19.7056 103919 105906 2 105906|105411 105602|103919 105816 103977 IPF468.1|IPF469.1|Contig4-2959_0006|orf6.8497|CaJ7.0077|orf19.7055.1|DIP53|CaO19_7056|CaJ7_0077|CA5640|CA5639|DIP53.exon2 Putative protein of unknown function, transcription is upregulated in clinical isolates from HIV+ patients with oral candidiasis; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=I] Ca21chr7 106320 106646 - orf19.7055 106320 106646 1 106646 106320 106646 106320 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 110736 111606 - ntar_1413 110736 111606 2 111606|111447 111537|110736 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 114110 114475 + orf19.7054 114110 114475 1 114110 114475 114110 114475 IPF27595.1|orf6.8499|CaJ7.0079|CaO19_7054|CaJ7_0079|CaO19.7054 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 115344 118048 + orf19.7053 115344 118048 1 115344 118048 115894 117909 GAC1 IPF461.2|orf6.8500|CA5641|CaJ7.0080|CaO19.7053|CaO19_7053|CaJ7_0080 Protein described as similar to regulatory subunit of serine/threonine phosphoprotein phosphatase 1; fluconazole-induced; caspofungin repressed; transcriptionally activated by Mnl1p under weak acid stress; regulated by Nrg1p, Tup1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 118938 119800 + ntar_1056 118938 119800 1 118938 119800 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 121266 121776 + ntar_1057 121266 121776 1 121266 121776 121419 121544 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 121720 122036 - ntar_1058 121720 122036 1 122036 121720 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 122253 122722 + ntar_1059 122253 122722 1 122253 122722 122503 122655 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 122788 126343 - orf19.7052 122788 126343 1 126343 122788 126245 122844 IPF451.1|Contig4-2871_0003|orf6.8501|CA5642|CaJ7.0081|CaO19.7052|INP52|CaO19_7052|CaJ7_0081 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 126488 127257 + orf19.7051 126488 127257 1 126488 127257 126561 127202 IPF448.1|Contig4-2871_0005|orf6.8502|CA5643|CaJ7.0082|CaO19_7051|CaJ7_0082|CaO19.7051|IPF448 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 127339 128230 + orf19.7050 127339 128230 1 127339 128230 127379 128182 NOP15 IPF447.1|Contig4-2838_0006|Contig4-2871_0006|orf6.8503|CA5644|CaJ7.0083|CaO19.7050|CaJ7_0083|CaO19_7050|IPF447 Protein described as a nucleolar ribosome biogenesis factor; hyphal-induced expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 128816 129003 - ntar_1060 128816 129003 1 129003 128816 128977 128825 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 128981 130056 + orf19.7049 128981 130056 1 128981 130056 129228 129608 CYB5 CYTB5|orf6.8505|orf6.8504|IPF443.1|Contig4-2871_0008|CA5645|CaJ7.0084|CaO19.7049|CaJ7_0084 Cytochrome b(5); not essential for viability; similar to S. cerevisiae Cyb5p; transcriptionally regulated by iron; expression greater in high iron; fluconazole-induced; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 131156 131385 + ntar_1061 131156 131385 1 131156 131385 131156 131296 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 131513 132202 + orf19.7048.1 131513 132202 2 131513|131660 131587|132202 131585 131860 RPS28B IPF440.1|CA5646|RPS28B.3f|RPS28B.3 Putative ribosomal protein S28B; ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 132399 134460 + orf19.7047 132399 134460 1 132399 134460 132567 134273 RTF1 orf6.8505|IPF3088.3|Contig4-2855_0020|orf6.7973|CA5228|CaJ7.0085|orf19.7048|RTF1.3f|RTF1.3eoc|IPF3088.2 Protein induced during the mating process [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 135413 136630 + orf19.7046 135413 136630 1 135413 136630 135510 136031 MET28 IPF3087.1|Contig4-2855_0006|orf6.7972|CA5227|CaJ7.0086|CaJ7_0086|CaO19_7046|CaO19.7046|IPF3087 Protein induced during the mating process [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 137132 143119 + orf19.7044 137132 143119 1 137132 143119 137282 143053 IPF3086.1|Contig4-2855_0009|orf6.7970|CA5226|CaJ7.0087|RIM15|CaO19.7044|CaO19_7044|CaJ7_0087 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr7 143330 144026 + orf19.7043.1 143330 144026 2 143330|143679 143555|144026 143529 143912 ACB1 IPF3082.1|CA5225|ACB1.3f|ACB1.exon2 Protein described as similar to a region of acyl-coenzyme-A-binding protein; amphotericin B repressed; regulated by Nrg1p, Tup1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 143480 144850 - orf19.7043 143480 144850 1 144850 143480 144569 144060 IPF3081.1|Contig4-2855_0014|orf6.7969|CA5224|CaJ7.0089|CaO19_7043|CaJ7_0089|CaO19.7043|IPF3081 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 145784 147120 + orf19.7042 145784 147120 1 145784 147120 145917 146819 IPF3080.2|IPF3080|Contig4-2855_0017|orf6.7968|CA5223|CaJ7.0090|CaO19_7042|CaJ7_0090|CaO19.7042 Increased transcription is observed upon benomyl treatment or in an azole-resistant strain that overexpresses MDR1; induced by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 147365 148008 - ntar_1062 147365 148008 1 148008 147365 148008 147790 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 148118 150555 + orf19.7041 148118 150555 1 148118 150555 148191 150485 IPF3079.2|Contig4-1858_0007|orf6.7967|CA5222|CaJ7.0091|CaO19.7041|PTA1|CaJ7_0091|CaO19_7041|IPF3079 Putative protein of unknown function; heterozygous null mutant exhibits hypersensitivity to parnafungin and cordycepin in the C. albicans fitness test; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 150729 153349 + orf19.7038 150729 153349 3 150729|152047|152204 151973|152117|153349 150850 153243 IPF3075.1|IPF3076.1|Contig4-1858_0003|orf6.7964|orf6.7965|CA5220|CaJ7.0093|orf19.7039|MVP1|CA5221|MVP1.exon1|MVP1.exon2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 153119 154027 - orf19.7037 153119 154027 1 154027 153119 153889 153347 YAE1 IPF3074.1|Contig4-1989_0001|orf6.7963|CA5219|CaJ7.0095|CaO19_7037|CaJ7_0095|CaO19.7037 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 153514 154013 + ntar_1063 153514 154013 1 153514 154013 153753 153881 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 154188 155954 + orf19.7036 154188 155954 1 154188 155954 154466 155746 IPF3073.1|Contig4-1989_0003|orf6.7962|CA5218|CaJ7.0096|CaO19.7036|WHI2|CaO19_7036|CaJ7_0096 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 155836 156039 - ntar_1064 155836 156039 1 156039 155836 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 156114 157329 + orf19.7035 156114 157329 1 156114 157329 156150 157241 RFC2 IPF3070.2|Contig4-2889_0019|orf6.7961|CA5217|CaJ7.0097|CaO19.7035|CaJ7_0097|CaO19_7035 Predicted ORF in Assemblies 19, 20 and 21; periodic mRNA expression, peak at cell-cycle G1/S phase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 157349 159972 - orf19.7034 157349 159972 1 159972 157349 159808 157502 IPF3069.2|Contig4-2889_0017|orf6.7960|CA5216|CaJ7.0098|CaO19.7034|CaO19_7034|CaJ7_0098|IPF3069 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 160489 164200 - orf19.7033 160489 164200 1 164200 160489 163943 160710 IPF3063.1|Contig4-2889_0013|orf6.7959|CA5215|CaJ7.0099|CaO19_7033|CaJ7_0099|CaO19.7033|PPS1 Putative dual specificity protein phosphatase, similar to S. cerevisiae Pps1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=G scenario_last_exon=G] Ca21chr7 164374 164624 - ntar_1065 164374 164624 1 164624 164374 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 165543 168940 + orf19.7032 165543 168940 1 165543 168940 165660 168671 IPF19807.1|Contig4-2889_0009|Contig4-2889_0010|orf6.7958|CA5214|CaJ7.0100|CaO19.7032|CaO19_7032|CaJ7_0100|IPF19807 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr7 168882 169463 - ntar_1066 168882 169463 1 169463 168882 169463 169287 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 171583 172766 + orf19.7030 171583 172766 1 171583 172766 171720 172424 SSR1 IPF3054.1|Contig4-2889_0002|orf6.7956|CA5213|CaJ7.0101|CaO19_7030|CaJ7_0101|CCW14|CaO19.7030 Beta-glucan associated cell-wall protein with role in cell wall structure; S/T rich protein, GPI anchor; similar mRNA abundance in yeast-form and germ tube; detected at germ tube plasma membrane by mass spec; similar to S. cerevisiae Ssr1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 174289 176121 + orf19.7029 174289 176121 1 174289 176121 174289 176121 IPF3050.2|Contig4-2889_0001|orf6.7955|CA5212|CaJ7.0103|CaJ7_0103|CaO19_7029|CaO19.7029|IPF3050 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to toxic ergosterol analog [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 176543 179318 - orf19.7027 176543 179318 1 179318 176543 179318 176562 IPF2373.2|IPF18125.1|orf6.7953|orf6.7954|CA5210|CA5211|CaJ7.0104|CaJ7.0105|orf19.7028|IPF2373 Predicted ORF in Assemblies 19, 20 and 21; merged with orf19.7028 in Assembly 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr7 181125 181362 + ntar_1067 181125 181362 1 181125 181362 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 183263 183626 - ntar_1068 183263 183626 1 183626 183263 183531 183352 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 184877 185312 - ntar_1069 184877 185312 1 185312 184877 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 185787 186357 - ntar_1070 185787 186357 1 186357 185787 186214 186089 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 187640 189480 - orf19.7025 187640 189480 2 189480|188837 189120|187640 188811 188023 MCM1 IPF2363.1|Contig4-3091_0013|Contig4-3091_0014|orf6.7951|CA5209|CaJ7.0107|CaO19.7025|CaO19_7025|CaJ7_0107 Transcription factor; regulator of hyphal growth; may act with Wor1p; canonical and non-canonical binding sites; MADS domain DNA-binding motif; similar to S. cerevisiae Mcm1p; greater expression in white than opaque cells; intron in 5'-UTR [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr7 189687 189995 + orf19.7024 189687 189995 1 189687 189995 189687 189995 IPF27598.1|orf6.7950|CaJ7.0108|CaO19.7024|CaO19_7024|CaJ7_0108 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 189935 191278 - orf19.7023 189935 191278 1 191278 189935 191255 190074 IPF2361.1|Contig4-3091_0017|orf6.7949|CA5208|CaJ7.0109|CaO19.7023|IOC4|CaJ7_0109|CaO19_7023|IPF2361 Predicted ORF in Assemblies 19, 20 and 21; oxidative stress-induced via Cap1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 190762 190914 + ntar_1071 190762 190914 1 190762 190914 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 191322 192530 - orf19.7022 191322 192530 1 192530 191322 192481 191453 IPF2359.1|Contig4-3091_0018|orf6.7948|CA5207|CaJ7.0110|CaO19_7022|CaJ7_0110|CaO19.7022|IPF2359 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 194025 194303 + ntar_1072 194025 194303 1 194025 194303 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 194541 197942 + orf19.7021 194541 197942 1 194541 197942 195079 197781 GPH1 orf6.7947|IPF2357.1|Contig4-3091_0021|Contig4-3091_0022|Contig4-3091_0024|CA5206|CaJ7.0111|CaO19.7021 Putative glycogen phosphorylase; gene regulated by Ssk1p, Mig1p, and Tup1p; fluconazole-induced; localizes to cell surface of hyphal cells, but not yeast-form cells; S. cerevisiae Gph1p is a stress-regulated protein of glycogen metabolism [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 197822 198031 - ntar_1073 197822 198031 1 198031 197822 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 198204 200652 + orf19.7020 198204 200652 1 198204 200652 198460 200568 orf6.7946|IPF2356.1|Contig4-3091_0027|CA5205|CaJ7.0112|KEX1|CaO19.7020|CaO19_7020|CaJ7_0112 Protein similar to S. cerevisiae Kex1p, which is a pheromone-processing peptidase; possible Kex2p substrate [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 200820 201775 + orf19.7019 200820 201775 1 200820 201775 200872 201708 YML6 IPF2354.1|Contig4-3091_0029|orf6.7945|CA5204|CaJ7.0113|CaO19.7019|CaO19_7019|CaJ7_0113 Protein described as a mitochondrial ribosomal protein; induced upon adherence to polystyrene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 202081 203426 + orf19.7018 202081 203426 2 202081|202692 202263|203426 202217 203082 RPS18 IPF2353.1|RPS18A|Contig4-3091_0033|orf6.7944|CA5203|CaJ7.0114 Predicted ribosomal protein; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 204965 206121 - orf19.7017 204965 206121 1 206121 204965 206040 205033 YOX1 IPF2351.1|Contig4-3091_0036|orf6.7943|CA5202|CaJ7.0115|CaO19.7017|CaJ7_0115|CaO19_7017 Predicted ORF in Assemblies 19, 20 and 21; periodic mRNA expression, peak at cell-cycle G1/S phase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 209102 211224 + orf19.7016 209102 211224 1 209102 211224 209134 211122 PHM5 IPF2349.1|Contig4-3091_0040|orf6.7942|CA5201|CaJ7.0116|CaJ7_0116|CaO19_7016|CaO19.7016|IPF2349 Protein not essential for viability; similar to S. cerevisiae Phm5p, which is a vacuolar endopolyphosphatase with a role in phosphate metabolism [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 211315 211522 - ntar_1074 211315 211522 1 211522 211315 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 211748 212803 + orf19.7015 211748 212803 1 211748 212803 211801 212739 RPP0 IPF2347.1|Contig4-3091_0041|orf6.7941|CA5200|RPL10E|CaJ7.0118|CaO19.7015|CaO19_7015|CaJ7_0118 Putative ribosomal protein; antigenic in mouse; biofilm induced; cytoplasmic ribosomal subunit, translation factor, and tRNA synthetase genes are downregulated upon phagocytosis by murine macrophage; transcription induced by Tbf1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 211827 212249 - orf19.7014 211827 212249 1 212249 211827 212249 211827 IPF2346.1|orf6.7940 [NOT TRANSCRIBED?] Putative protein of unknown function, transcription is positively regulated by Tbf1p; ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 212898 214127 + orf19.7013 212898 214127 1 212898 214127 212898 214127 IPF2344.1|Contig4-3091_0044|orf6.7939|CA5199|CaJ7.0119|CaO19_7013|CaJ7_0119|CaO19.7013|IPF2334 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 213745 214766 - orf19.7012 213745 214766 1 214766 213745 214766 214245 IPF2343.1|Contig4-3091_0045|orf6.7938|CA5198|CaJ7.0120|CaO19.7012|MRPS16|CaJ7_0120|CaO19_7012|LPA4 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 214874 218604 - orf19.7011 214874 218604 1 218604 214874 218578 214925 IPF2342.1|Contig4-3091_0046|orf6.7937|CA5197|CaJ7.0121|CaO19_7011|CaJ7_0121|CaO19.7011|IPF2342 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 218711 220703 - orf19.7010 218711 220703 1 220703 218711 220611 218779 IPF2338.1|Contig4-3091_0047|orf6.7936|CA5196|CaJ7.0122|CaO19.7010|CaJ7_0122|CaO19_7010|IPF2338 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 221546 222589 + orf19.7009 221546 222589 1 221546 222589 221546 222589 IPF2336.2|Contig4-3091_0050|orf6.7935|CA5195|CaJ7.0123|CaO19_7009|CaJ7_0123|CaO19.7009|GRP8 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chr7 222726 223154 + orf19.7007 222726 223154 1 222726 223154 222726 223154 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 223232 226823 - orf19.7006 223232 226823 2 226823|226556 226630|223232 226653 223296 IPF11756.2|orf6.7932|CA5194|CaJ7.0126|CaO19_7006|CaJ7_0126|IPF11756 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 227090 227285 + ntar_1075 227090 227285 1 227090 227285 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 227724 227868 - ntar_1076 227724 227868 1 227868 227724 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 230874 232412 - orf19.6896 230874 232412 1 232412 230874 232412 230874 IPF20171.1|orf6.7160|CaO19.6896 Predicted ORF in Assemblies 19, 20 and 21; member of a family encoded by FGR6-related genes in the RB2 repeat sequence [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 236122 236562 - orf19.6897 236122 236562 1 236562 236122 236562 236122 IPF2239.1|Contig4-2914_0012|Contig4-2965_0012|orf6.7161|CaJ7_0131|CaO19_7003|CaO19.6897 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 244174 245485 + orf19.6898 244174 245485 1 244174 245485 244260 245342 IPF2234.1|Contig4-3039_0003|orf6.7162|CA4579|CaJ7.0132|CaO19.6898|CaO19_6898|CaJ7_0132|IPF2234 Predicted ORF in Assemblies 19, 20 and 21; increased transcription is observed upon benomyl treatment or in an azole-resistant strain that overexpresses MDR1 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr7 245096 245793 - orf19.6898.1 245096 245793 1 245793 245096 245755 245477 IPF2233.1|Contig4-3039_0004|CA4580|CaJ7.s006|CaJ7_s006|IPF2233 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 246057 247319 - orf19.6899 246057 247319 1 247319 246057 247260 246118 IPF2232.1|Contig4-3039_0005|orf6.7163|CA4581|CaJ7.0133|CaO19.6899|QTH1|CaO19_6899|CaJ7_0133|IPF2232 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to toxic ergosterol analog [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 248212 249663 + orf19.6900 248212 249663 1 248212 249663 248252 249538 IPF2231.1|Contig4-3039_0007|orf6.7164|CA4582|CaJ7.0134|CaO19_6900|CaJ7_0134|CaO19.6900|MDM12 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 249830 250808 + orf19.6901 249830 250808 1 249830 250808 249862 250770 IPF2229.1|Contig4-3039_0009|orf6.7165|CA4583|CaJ7.0135|CaO19.6901|DCS1|CaO19_6901|CaJ7_0135|IPF2229 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 250786 253013 - orf19.6902 250786 253013 1 253013 250786 252977 250794 DBP7 IPF2228.1|Contig4-3039_0010|orf6.7166|CA4584|CaJ7.0136|CaO19.6902|CaO19_6902|CaJ7_0136|IPF2228 Predicted ORF in Assemblies 19, 20 and 21; transcription is upregulated in both intermediate and mature biofilms [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 253215 254222 - orf19.6903 253215 254222 1 254222 253215 254185 253349 IPF2227.1|Contig4-3039_0012|orf6.7167|CA4585|CaJ7.0137|CaO19_6903|CaJ7_0137|CaO19.6903|RPC37|IPF2227 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 254332 255411 + orf19.6904 254332 255411 1 254332 255411 254406 255341 GCN3 IPF2224.1|Contig4-3039_0014|orf6.7168|CA4586|CaJ7.0138|CaO19.6904|CaJ7_0138|CaO19_6904 Protein described as a translation initiator; downregulated in the presence of human whole blood or polymorphonuclear (PMN) cells [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 255334 256968 - orf19.6905 255334 256968 1 256968 255334 256808 255375 IPF2223.1|Contig4-3039_0015|orf6.7169|CA4587|CaJ7.0139|CaO19.6905|CaO19_6905|CaJ7_0139|IPF2223 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 257888 259254 + orf19.6906 257888 259254 2 257888|258701 258441|259254 257914 259126 ASC1 orf6.7170|Contig4-3039_0017|IPF2221.1|Contig4-3039_0016|orf19.6906.1|BEL1|CA4588|CaJ7.0140|CA4589|BEL1.exon2|IPF2220.1|BEL1.exon1 40S ribosomal subunit protein; similar to G-beta subunits; antigenic in human, murine infection; soluble in hyphae; iron, temperature, Gcn4p regulated; amino acid starvation (3-aminotriazole)-, caspofungin-, farnesol-downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 259189 261114 - orf19.6907 259189 261114 1 261114 259189 261084 259276 IPF2218.1|Contig4-3039_0019|orf6.7171|CA4590|CaJ7.0141|CaO19.6907|CaO19_6907|CaJ7_0141|IPF2218 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 261172 262706 - orf19.6908 261172 262706 1 262706 261172 262554 261262 IPF2216.1|Contig4-3039_0020|orf6.7172|CA4591|CaJ7.0142|CaO19.6908|CaJ7_0142|CaO19_6908|IPF2216 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 261392 261619 + ntar_1077 261392 261619 1 261392 261619 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 263199 263962 + orf19.6909 263199 263962 1 263199 263962 263354 263860 IPF2215.1|Contig4-3039_0022|orf6.7173|CA4592|CaJ7.0143|CaJ7_0143|CaO19_6909|MED11|CaO19.6909|IPF2215 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 263627 264635 - orf19.6910 263627 264635 1 264635 263627 264608 263898 PSF1 IPF2214.1|Contig4-3039_0023|orf6.7174|CA4593|CaJ7.0144|CaO19.6910|CaJ7_0144|CaO19_6910|IPF2214 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 264746 265075 - orf19.6911 264746 265075 1 265075 264746 265075 264746 IPF27390.1|orf6.7175|CaJ7.0145|CaO19_6911|CaJ7_0145|CaO19.6911 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 265205 265638 - ntar_1078 265205 265638 1 265638 265205 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 265207 265631 + ntar_1079 265207 265631 1 265207 265631 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 265836 268046 + orf19.6912 265836 268046 1 265836 268046 266121 267941 IPF2212.2|Contig4-3039_0027|orf6.7176|CA4594|CaJ7.0146|CaO19.6912|CaO19_6912|CaJ7_0146|IPF2212 Putative ethanolamine kinase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 268048 273403 - orf19.6913 268048 273403 1 273403 268048 273403 268109 GCN2 IPF2209.2|Contig4-2889_0013|orf6.7177|CA4595|CaJ7.0147|CaO19_6913|CaJ7_0147|CaO19.6913 Translation initiation factor 2-alpha (eIF2alpha) kinase; has nonessential role in amino acid starvation response, in contrast to S. cerevisiae homolog; similar to S. cerevisiae Gcn2p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr7 273590 275831 + orf19.6915 273590 275831 1 273590 275831 273671 275719 MRE11 IPF2205.1|Contig4-2895_0002|orf6.7179|CA4596|CaJ7.0149|CaJ7_0149|CaO19_6915|CaO19.6915 Protein described as DNA double-strand break repair factor; involved in response to oxidative stress and drug resistance [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 275665 276829 - orf19.6916 275665 276829 1 276829 275665 276747 275788 IPF2203.1|Contig4-2895_0003|orf6.7180|CA4597|CaJ7.0150|CaO19_6916|CaJ7_0150|ATP11|CaO19.6916 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 276990 277813 - orf19.6917 276990 277813 1 277813 276990 277738 277184 IPF20019.1|Contig4-2895_0005|orf6.7181|CA4598|CaJ7.0151|CaO19_6917|CaJ7_0151|CaO19.6917|FMP28|IPF20019 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 276994 277219 + ntar_1080 276994 277219 1 276994 277219 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 277907 279713 + orf19.6918 277907 279713 1 277907 279713 278055 279503 IPF2200.2|Contig4-2895_0007|orf6.7182|CA4599|CaJ7.0152|CaO19.6918|CaJ7_0152|CaO19_6918|IPF2200 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 281285 282544 + orf19.6919 281285 282544 1 281285 282544 281377 282504 IPF2199.2|orf6.7183|CA4600|CaJ7.0153|CaJ7_0153|CaO19_6919|CaO19.6919|IPF2199 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr7 283899 284141 - ntar_1081 283899 284141 1 284141 283899 284141 283947 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 284169 284415 - ntar_1082 284169 284415 1 284415 284169 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 285534 286610 + orf19.6920 285534 286610 1 285534 286610 285902 286294 IPF2195.1|Contig4-2895_0017|orf6.7184|CA4601|CaJ7.0154|CaO19.6920|CaO19_6920|CaJ7_0154|IPF2195 Predicted ORF in Assemblies 19, 20 and 21; induced upon biofilm formation; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 286659 289251 - orf19.6921 286659 289251 1 289251 286659 289095 286777 IPF2194.3|orf6.7185|CA6241|CaJ7.0155|CaO19.6921|IPF2194.3eoc Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr7 289570 289830 + ntar_1083 289570 289830 1 289570 289830 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 289898 291653 - orf19.6588 289898 291653 1 291653 289898 291141 290113 orf19.13941|IPF20610.1|IPF18160.1|orf6.7576|CA4896|CaJ7.0156|CaO19.6588|NBP2|CaO19_6588|CaJ7_0156|CaO19.13941|IPF18160 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 292151 293326 + orf19.6587 292151 293326 1 292151 293326 292254 293033 orf19.13940|IPF20628.1|IPF18161.1|Contig4-2926_0004|orf6.7575|YDR152W|CA4895|CaJ7.0157|CaO19.13940|CaO19.6587|CaJ7_0157|CaO19_6587|IPF18161 Protein similar to S. cerevisiae Ydr152wp; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 293944 294511 - ntar_1084 293944 294511 1 294511 293944 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 294976 295353 - ntar_1085 294976 295353 1 295353 294976 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 295505 296973 - orf19.6586 295505 296973 1 296973 295505 296775 295834 orf19.13939|IPF20613.1|IPF1617.2|Contig4-3066_0026|orf6.7574|CA4894|CaJ7.0158|CaO19.6586|CaJ7_0158|CaO19_6586|CaO19.13939|IPF1617 Predicted ORF in Assemblies 19, 20 and 21; increased transcription is observed upon benomyl treatment or in an azole-resistant strain that overexpresses MDR1; shows colony morphology-related gene regulation by Ssn6p; induced by nitric oxide, 17-beta-estradiol, ethynyl estradiol; macrophage-downregulated gene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 297519 297708 + ntar_1086 297519 297708 1 297519 297708 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 298095 298362 + ntar_1087 298095 298362 1 298095 298362 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 302301 303061 + orf19.6585 302301 303061 1 302301 303061 302677 303045 orf19.13938|IPF20669.1|IPF1621.1|Contig4-3066_0017|orf6.7573|CA4893|CaJ7.0159|CaO19.6585|CaO19.13938|CaJ7_0159|CaO19_6585|IPF1621 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 303017 305451 - orf19.6584 303017 305451 1 305451 303017 305372 303153 PRT1 orf19.13937|IPF20551.1|IPF1623.1|Contig4-3066_0014|Contig4-3066_0016|orf6.7572|CA4892|CaJ7.0160|CaO19_6584|CaJ7_0160|CaO19.13937|CaO19.6584 Putative translation initiation factor; mutation confers hypersensitivity to roridin A and verrucarin A; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 305591 308922 - orf19.6583 305591 308922 1 308922 305591 308850 305830 orf19.13936|IPF20699.1|IPF1627.1|Contig4-3066_0013|orf6.7571|CA4891|CaJ7.0161|CaO19.13936|CaJ7_0161|CaO19_6583|CaO19.6583|IPF1627 Predicted ORF in Assemblies 19, 20 and 21; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 309107 310229 - orf19.6582 309107 310229 3 310229|310103|309979 310165|310055|309107 310167 309231 PRE10 orf19.13935|PRS1|IPF20631.1|IPF1628.1|Contig4-3066_0011|orf6.7570|CA4890|CaJ7.0162|CaO19.6582|CaO19.13935 Alpha7 (C8) subunit of the 20S proteasome; multiple phosphorylated residues; transcription is induced upon filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 310325 311855 + orf19.6581 310325 311855 1 310325 311855 310447 311787 orf19.13934|IPF20599.1|IPF1629.1|Contig4-3066_0010|orf6.7569|CA4889|CaJ7.0163|CaO19.6581|CaO19_6581|CaJ7_0163|CaO19.13934|IPF1629 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 312498 313488 + orf19.6580 312498 313488 1 312498 313488 312572 313264 orf19.13933|IPF20635.1|IPF1631.2|Contig4-2945_0012|Contig4-3066_0007|orf6.7568|CA4888|CaJ7.0164|CaO19.6580|CaO19_6580|CaJ7_0164|CaO19.13933|IPF1631 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 313739 315149 + orf19.6579 313739 315149 1 313739 315149 313807 315117 orf19.13932|IPF20602.1|IPF1632.1|Contig4-3066_0005|orf6.7567|CA4887|CaJ7.0165|CaJ7_0165|CaO19_6579|CaO19.6579|CaO19.13932|IPF1632 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 314661 315407 - ntar_1088 314661 315407 1 315407 314661 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 316935 318928 + orf19.6578 316935 318928 1 316935 318928 317086 318729 orf19.13931|IPF20585.1|IPF1634.1|Contig4-3066_0002|orf6.7566|CA4886|CaJ7.0166|CaO19.6578|CaO19.13931|CaO19_6578|CaJ7_0166|IPF1634 Predicted membrane transporter, member of the vesicular neurotransmitter (VNT) family, major facilitator superfamily (MFS); downregulated in core caspofungin response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 320478 322558 + orf19.6577 320478 322558 1 320478 322558 320557 322389 FLU1 orf19.13930|IPF20574.1|IPF1636.1|orf6.7565|TPO1|CA4885|CaJ7.0168|CaO19.13930|CaO19.6577|CaO19_6577|CaJ7_0168|IPF1636 Multidrug efflux pump of the plasma membrane; member of the MDR family of the MFS (major facilitator superfamily) of transporters; preferred substrate may be mycophenolic acid; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 322603 322846 - ntar_1089 322603 322846 1 322846 322603 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 322905 323231 + orf19.6575 322905 323231 1 322905 323231 322905 323231 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 325172 326695 + orf19.6574 325172 326695 1 325172 326695 325172 326695 ALK6 orf19.13927|IPF20591.1|IPF1640.1|Contig4-2887_0006|orf6.7562|CA4884|CaJ7.0170|CaO19.13927|CaJ7_0170|CaO19_6574|CaO19.6574 Protein described as cytochrome P-450 of N-alkane-induced detoxification; macrophage-induced gene [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 328989 329244 + ntar_1090 328989 329244 1 328989 329244 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 329582 336627 + orf19.6573 329582 336627 1 329582 336627 329717 336475 BEM2 orf19.13926|IPF20639.1|IPF1649.2|Contig4-2887_0010|Contig4-2887_0011|orf6.7561|CA4883|CaJ7.0172|CaO19.13926|CaJ7_0172|CaO19_6573|CaO19.6573|IPF1649 Putative Rho1p GTPase activating protein (GAP); serum-induced transcription [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 336493 338329 - orf19.6570 336493 338329 1 338329 336493 337899 336679 NUP orf19.13923|orf6.7558|IPF20601.1|IPF1651.1|Contig4-2887_0014|CA4882|CaJ7.0175|NUP32|CaO19.6570|CaO19.13923|CaJ7_0175|CaO19_6570|IPF1651 Nucleoside permease; adenosine and guanosine are substrates, whereas cytidine, adenine, guanine, uridine, uracil are not; similar to a nucleoside permease of S. pombe; possibly processed by Kex2p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 338425 340022 - orf19.6569 338425 340022 1 340022 338425 339885 338749 orf19.13922|IPF20612.1|IPF1652.2|Contig4-2887_0015|orf6.7557|CA4881|CaJ7.0176|CaO19.13922|NUP31|CaJ7_0176|CaO19_6569|CaO19.6569|IPF1652 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr7 340449 344150 + orf19.6568 340449 344150 1 340449 344150 340592 343978 SMC6 orf19.13921|IPF20688.1|IPF1656.2|Contig4-2941_0016|Contig4-2941_0018|orf6.7556|CA4880|CaJ7.0178|RHC18|CaO19.13921|CaO19.6568|CaJ7_0178|CaO19_6568 Predicted ORF in Assemblies 19, 20 and 21; cell-cycle regulated periodic mRNA expression; S. cerevisiae ortholog is not cell-cycle regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 343941 345627 - orf19.6566 343941 345627 1 345627 343941 345577 344246 orf19.13919|IPF20598.1|IPF1660.1|Contig4-2941_0014|orf6.7554|CA4879|CaJ7.0179|CaO19.6566|CaO19.13919|CaO19_6566|CaJ7_0179|IPF1660 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 345759 346996 + orf19.6565 345759 346996 1 345759 346996 345796 346920 orf19.13918|IPF20609.1|IPF1663.1|Contig4-2941_0012|orf6.7553|CA4878|CaJ7.0180|CaO19.13918|OXA1|CaJ7_0180|CaO19_6565|CaO19.6565 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 347193 347898 + orf19.6563.1 347193 347898 2 347193|347341 347269|347898 347247 347584 IPF20539.1|IPF1665.1|Contig4-2941_0010|CA6231|IPF1665 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 347665 350071 - orf19.6563 347665 350071 1 350071 347665 349794 347815 orf19.13916|IPF20564.1|IPF1667.1|Contig4-2941_0009|orf6.7551|CA4877|CaJ7.0182|CaO19.6563|CaO19.13916|CaO19_6563|CaJ7_0182|IPF1667 Predicted ORF in Assemblies 19, 20 and 21; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr7 350991 352332 + orf19.6562 350991 352332 1 350991 352332 350991 352286 RNH35 orf19.13915|IPF20603.1|IPF1669.1|Contig4-2941_0008|orf6.7550|CA4876|CaJ7.0183|CaO19_6562|CaJ7_0183|CaO19.13915|CaO19.6562 Predicted ORF in Assemblies 19, 20 and 21; flucytosine induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 351604 352172 - ntar_1091 351604 352172 1 352172 351604 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 352514 354302 + orf19.6561 352514 354302 1 352514 354302 352680 354113 LAT1 orf19.13914|IPF20596.1|IPF1673.1|Contig4-2941_0006|orf6.7549|CA4875|CaJ7.0184|CaJ7_0184|CaO19_6561|CaO19.6561|CaO19.13914 Protein described as dihydrolipoamide acetyltransferase component (E2) of pyruvate dehydrogenase complex [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 354377 356259 + orf19.6559 354377 356259 2 354377|355590 355449|356259 354544 356141 orf19.13912|IPF20619.1|IPF1674.1|Contig4-2941_0005|orf6.7547|CaJ7.0186|orf19.6558.1|CA4874|IPF1674|CA4873|IPF1674.3|IPF1675.1 Predicted ORF in Assemblies 19, 20 and 21; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 355701 355951 - ntar_1092 355701 355951 1 355951 355701 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 356056 358669 - orf19.6558 356056 358669 1 358669 356056 358624 356177 orf19.13911|IPF20542.1|IPF1677.1|Contig4-2941_0003|orf6.7546|CA4872|CaJ7.0187|CaJ7_0187|CaO19_6558|CaO19.6558|SEC232|sec231|CaO19.13911 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 358993 361088 + orf19.6557 358993 361088 1 358993 361088 359158 360897 orf19.13910|IPF20579.1|IPF1680.2|orf6.7545|CA4871|CaJ7.0188|CaJ7_0188|CaO19_6557|AMD23|CaO19.13910|CaO19.6557|IPF1680 Predicted ORF in Assemblies 19, 20 and 21; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 361267 361526 - ntar_1093 361267 361526 1 361526 361267 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 362557 362805 + ntar_1094 362557 362805 1 362557 362805 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 363269 364547 - orf19.6556 363269 364547 1 364547 363269 364477 363743 orf19.13909|IPF19569.2|IPF19568.1|orf6.330|orf6.7544|CA4870|CaJ7.0190|CaJ7_0190|CaO19_6556|CaO19.6556|IPF19568 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 369310 369888 + orf19.6555 369310 369888 1 369310 369888 369532 369888 orf19.13908|IPF12086.3|IPF27693.1|Contig4-2437_0006|orf6.5259|orf6.7543|CaJ7.0191|CaO19.6555|CaJ7_0191|CaO19_6555|CA3103|IPF12086|IPF12086.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr7 369388 369952 - ntar_1095 369388 369952 1 369952 369388 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 369893 371298 + orf19.6554 369893 371298 1 369893 371298 370382 371209 orf19.13907|IPF12084.2|IPF27690.1|Contig4-2437_0009|orf6.5260|CA3104|CaJ7.0193|CaO19.13907|CaO19.6554|CaO19_6554|CaJ7_0193|IPF12084 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 371419 372802 + orf19.6553 371419 372802 1 371419 372802 371483 372664 orf19.13906|IPF20605.1|IPF12083.2|Contig4-2437_0010|Contig4-2620_0015|orf6.5261|CA3105|CaJ7.0194|CaJ7_0194|CaO19_6553|CaO19.13906|CaO19.6553|IPF12083 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 372909 374018 + orf19.6552 372909 374018 1 372909 374018 373131 373895 orf19.13905|IPF20621.1|IPF11821.1|Contig4-2620_0014|orf6.5262|CA3106|CaJ7.0195|ERV2|CaO19.13905|CaO19.6552|CaJ7_0195|CaO19_6552|IPF11821 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 373862 374407 - orf19.6551.1 373862 374407 2 374407|374150 374219|373862 374340 374000 STE18 IPF20592.1|IPF11823.2 ORF Predicted by Annotation Working Group; similar to S. cerevisiae Ste18p; expressed in opaque or white MTLa/MTLa or MTLalpha/MTLalpha, but not MTLa/MTLalpha cells; MTLa1p, MTLalpha2p bind promoter region [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 374452 375371 - orf19.6551 374452 375371 1 375371 374452 375266 374592 orf19.13904|IPF20637.1|IPF11824.2|Contig4-2620_0009|orf6.5263|CA3107|CaJ7.0196|CaJ7_0196|CaO19_6551|GOS1|CaO19.13904|CaO19.6551 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 375608 376843 + orf19.6550 375608 376843 1 375608 376843 375746 376630 orf19.13903|IPF20615.1|IPF11826.1|Contig4-2620_0007|orf6.5264|CA3108|CaJ7.0197|CaO19.6550|CaO19_6550|CaJ7_0197|CaO19.13903|IPF11826 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 377091 377976 - orf19.6548 377091 377976 1 377976 377091 377787 377224 ISU1 orf19.13901|orf6.5266|IPF20648.1|IPF11829.1|Contig4-2620_0004|CA3109|CaJ7.0199|CaO19_6548|CaJ7_0199|CaO19.6548|CaO19.13901|IPF11829 Protein with similarity to NifU; possible role in iron-sulfur cluster biogenesis; transcriptionally regulated by iron; expression greater in low iron; transcription is upregulated in both intermediate and mature biofilms [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 379041 379388 + orf19.6547 379041 379388 1 379041 379388 379041 379388 orf19.13900|IPF20684.1|IPF27704.1|orf6.5267|CaJ7.0200|CaO19.6547|CaO19.13900|CaJ7_0200|CaO19_6547 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 379757 379990 - ntar_1096 379757 379990 1 379990 379757 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 380169 384432 + orf19.6544 380169 384432 1 380169 384432 380244 384338 LPI9 orf19.13897|IPF20671.1|IPF15433.2|Contig4-2763_0002|orf6.5271|CA3110|CaJ7.0205|CaJ7_0205|CaO19_6544|CaO19.6544|CaO19.13897 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 384385 385434 - orf19.6541 384385 385434 1 385434 384385 385385 384489 RPL5 orf19.13894|IPF20618.1|IPF10601.1|Contig4-2763_0003|orf6.5273|CA3111|CaJ7.0206|CaO19_6541|CaJ7_0206|CaO19.6541|CaO19.13894 Predicted ribosomal protein; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 385902 389242 - orf19.6540 385902 389242 1 389242 385902 388800 385960 PFK2 orf19.13893|IPF20535.1|IPF10598.1|Contig4-2763_0005|orf6.5274|CA3112|CaJ7.0207|CaO19_6540|CaJ7_0207|CaO19.6540|CaO19.13893 Beta subunit of phosphofructokinase (PFK), which is a heteromultimer of Pfk1p and Pfk2p; PFK is activated by fructose 2,6-bisphosphate or AMP, inhibited by ATP; downregulated upon phagocytosis or hyphal growth; fluconazole-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 389258 389619 - ntar_1098 389258 389619 1 389619 389258 389449 389258 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 389403 389879 + ntar_1097 389403 389879 1 389403 389879 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 390088 391981 + orf19.6539 390088 391981 1 390088 391981 390349 391845 orf19.13892|IPF15737.2|IPF27689.1|Contig4-3024_0004|Contig4-3024_0006|orf6.5275|CA3113|CaJ7.0208|RVB2|CaO19.13892|CaJ7_0208|CaO19_6539|CaO19.6539|IPF15737 Predicted ORF in Assemblies 19, 20 and 21; heterozygous null mutant displays sensitivity to virgineone [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 391755 392728 - orf19.6538 391755 392728 1 392728 391755 392513 392022 VMA11 orf19.13891|IPF20656.1|IPF5167.3|Contig4-3024_0007|orf6.5276|orf6.7622|CA4937|CaJ7.0209|TFP3|CaJ7_0209|CaO19_6538|CaO19.6538|IPF5167.2 Predicted ortholog of S. cerevisiae Tfp3p, which is the c' subunit of the V0 subcomplex of the vacuolar ATPase; required for hemoglobin-iron utilization [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 392827 394235 + orf19.6537 392827 394235 1 392827 394235 393005 393697 orf19.13890|IPF20633.1|IPF5166.1|Contig4-3024_0011|orf6.7623|CA4938|CaJ7.0210|CaO19.6537|CaO19.13890|CaO19_6537|CaJ7_0210|IPF5166 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 394310 399543 + orf19.6536 394310 399543 1 394310 399543 394417 399360 IQG1 orf19.13889|IPF20657.1|IPF5165.2|Contig4-3024_0013|Contig4-3024_0015|orf6.7624|CA4939|CaJ7.0211|CaJ7_0211|CaO19_6536|CaO19.13889|CaO19.6536 Component of actomyosin ring at bud neck; cell-cycle regulated serine phosphorylation at CDK sites regulates association with formins Bni1p and Bnr1p, Iqg1p degradation, and ring disassembly; mutation causes severe cytokinetic defects [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 399187 401832 - orf19.6534.2 399187 401832 2 401832|401585 401740|399187 401744 399689 orf19.13888|IPF20667.1|IPF5159.1|Contig4-3024_0017|Contig4-3024_0018|Contig4-3024_0019|orf6.7625|CA4942|CA4940|CaJ7.0212|orf19.6535|CRN1.5f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 401552 402022 + orf19.6534 401552 402022 1 401552 402022 401552 402022 orf19.13887|IPF20649.1|IPF5158.1|Contig4-3024_0020|Contig4-3024_0021|orf6.7626|CA4943|CaO19.13887|CaO19.6534|IPF5158 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 402312 404200 + orf19.6533 402312 404200 1 402312 404200 402406 404013 MSK1 orf19.13886|IPF20587.1|IPF5156.2|Contig4-3024_0022|orf6.7627|CA4944|CaJ7.0215|CaJ7_0215|CaO19_6533|CaO19.6533|CaO19.13886 Predicted ORF in Assemblies 19, 20 and 21; flucytosine repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 404066 405221 - orf19.6532 404066 405221 1 405221 404066 405125 404175 orf19.13885|IPF20616.1|IPF5154.2|Contig4-3024_0023|orf6.7628|CA4945|CaJ7.0216|FLX1|CaO19.6532|CaO19_6532|CaJ7_0216|CaO19.13885 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 405413 405897 - orf19.6531.1 405413 405897 1 405897 405413 405841 405644 TOM71 IPF20562.1|IPF5151.1|Contig4-3024_0026|CA4946|CaJ7.s008|CaJ7_s008 ORF Predicted by Annotation Working Group; flucytosine induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 406542 408305 + orf19.6531 406542 408305 1 406542 408305 406704 408140 NUC2 orf19.13884|IPF20595.1|IPF5150.1|Contig4-3024_0028|orf6.7629|CA4947|CaJ7.0217|CaO19.13884|CaO19.6531|CaO19_6531|CaJ7_0217 Protein described as NADH-ubiquinone oxidoreductase; identified in detergent-resistant membrane fraction (possible lipid raft component); alkaline downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 408234 409326 - orf19.6530 408234 409326 1 409326 408234 409302 408388 orf19.13883|orf6.7630|IPF20620.1|IPF5149.1|Contig4-3024_0029|CA4948|CaJ7.0218|CaO19.13883|CaO19.6530|CaO19_6530|CaJ7_0218|IPF5149 Similar to bacterial DnaJ; transcriptionally regulated by iron; expression greater in low iron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr7 410427 410700 - ntar_1099 410427 410700 1 410700 410427 410642 410427 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 410720 412282 + orf19.6529 410720 412282 1 410720 412282 411055 411789 CDC34 orf19.13882|IPF20629.1|IPF5145.1|Contig4-3024_0032|orf6.7631|CA4949|CaJ7.0219|UBC3|CaO19.6529|CaJ7_0219|CaO19_6529|CaO19.13882 Transcription is regulated by Nrg1p and Tup1p, and by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 412205 413059 - orf19.6528 412205 413059 1 413059 412205 412924 412313 orf19.13881|IPF20638.1|IPF5143.1|Contig4-3024_0033|orf6.7632|CA4950|CaJ7.0220|CaO19.13881|CaO19.6528|CaJ7_0220|CaO19_6528|IPF5143 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 413170 416769 - orf19.6527 413170 416769 1 416769 413170 416612 413295 orf19.13880|IPF20693.1|IPF13607.2|Contig4-2478_0007|orf6.7633|CA4951|CaJ7.0221|CaJ7_0221|CaO19_6527|PRM10|CaO19.6527|CaO19.13880|IPF13607 Predicted ORF in Assemblies 19, 20 and 21; shows colony morphology-related gene regulation by Ssn6p; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 418224 419361 + orf19.6526 418224 419361 1 418224 419361 418443 419297 orf19.13879|IPF20625.1|IPF13609.2|Contig4-2478_0002|Contig4-3089_0053|orf6.7634|CA4952|CaJ7.0222|CaO19.6526|RBD2|CaO19.13879|CaJ7_0222|CaO19_6526|IPF13609 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 419701 422181 + orf19.6525 419701 422181 1 419701 422181 419932 421986 orf19.13878|IPF20552.1|IPF4567.2|Contig4-3089_0049|Contig4-3089_0050|orf6.7635|CA4953|CaJ7.0223|IPF4567.3f|IPF4567.3 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction); transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 422152 423519 - orf19.6524 422152 423519 1 423519 422152 423405 422233 orf19.13877|IPF20607.1|IPF4568.1|Contig4-3089_0047|Contig4-3089_0048|orf6.7636|CA4954|CaJ7.0224|CaO19.6524|TOM40|CaO19.13877|CaO19_6524|CaJ7_0224 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 423725 425008 + ntar_1100 423725 425008 1 423725 425008 424877 425008 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 429774 431979 - orf19.6522 429774 431979 1 431979 429774 431707 429947 orf19.13875|IPF20575.1|IPF4580.2|Contig4-3089_0035|orf6.7638|CA4955|CaJ7.0227|CaO19.13875|CaO19.6522|CaO19_6522|CaJ7_0227|IPF4580 Putative allantoate permease; fungal-specific (no human or murine homolog); Gcn4p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr7 432217 433893 - orf19.6520 432217 433893 1 433893 432217 433893 432217 orf19.13873|IPF20583.1|IPF4583.2|Contig4-3089_0033|orf6.7640|CA4956|CaJ7.0229|CaO19.13873|CaO19.6520|CaJ7_0229|CaO19_6520|IPF4583 Putative allantoate permease; fungal-specific (no human or murine homolog) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 435231 437288 - orf19.6518 435231 437288 1 437288 435231 437288 435303 orf19.13871|IPF20569.1|IPF4588.2|Contig4-3089_0030|orf6.7642|CA4957|CaJ7.0231|CaO19.13871|CaJ7_0231|CaO19_6518|CaO19.6518|IPF4588|CA2507|IPF18459.3eoc|IPF18459.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr7 438034 439324 + orf19.6517 438034 439324 1 438034 439324 438038 439228 RAD14 orf19.13870|IPF20611.1|IPF4591.1|Contig4-3089_0028|orf6.7643|CA4958|CaJ7.0232|CaJ7_0232|CaO19_6517|CaO19.6517|CaO19.13870 Transcription is regulated upon yeast-hyphal switch; flucytosine repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 439490 441741 + orf19.6515 439490 441741 1 439490 441741 439531 441654 HSP90 orf19.13868|orf6.7645|IPF20556.1|IPF4596.2|Contig4-3089_0026|CA4959|CaJ7.0234|CaO19.6515|CaO19.13868|CaJ7_0234|CaO19_6515 Essential chaperone of Hsp90 family, activated by heat shock and stress; regulates several signal transduction pathways; localizes to surface of hyphae, but not yeast-form cells; mediates echinocandin resistance [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 444061 444994 - ntar_1101 444061 444994 1 444994 444061 444716 444507 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 445334 445896 - ntar_1102 445334 445896 1 445896 445334 445831 445703 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 445802 445960 + ntar_1103 445802 445960 1 445802 445960 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 449719 451046 - orf19.6514 449719 451046 1 451046 449719 450910 449876 CUP9 orf19.13867|IPF20614.1|IPF3912.1|Contig4-3089_0018|orf6.7646|CA4960|CaJ7.0235|CaO19.13867|CaO19_6514|CaJ7_0235|CaO19.6514|IPF3912 Protein of unknown function, upregulated in clinical isolates from HIV+ patients with oral candidiasis; transcription reduced upon yeast-hyphal switch; ketoconazole-induced; Plc1p-regulated; shows colony morphology-related Ssn6p regulation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 455152 457547 - orf19.6512 455152 457547 1 457547 455152 457369 455366 EXO70 orf19.13865|IPF20563.1|IPF3916.2|Contig4-3089_0010|orf6.7648|CA4961|CaJ7.0236|CaO19.6512|CaJ7_0236|CaO19_6512|CaO19.13865|IPF3916 Predicted ORF in Assemblies 19, 20 and 21; induced during planktonic growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 458168 460874 + orf19.6511 458168 460874 1 458168 460874 458226 460724 LIG1 orf19.13864|IPF20541.1|IPF3918.2|Contig4-3089_0004|Contig4-3089_0005|orf6.7649|CA4962|TRL1|CaJ7.0238|CaO19_6511|CaJ7_0238|CaO19.13864|CaO19.6511 tRNA ligase; functional homolog of S. cerevisiae Trl1p; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 461000 461371 + orf19.6510 461000 461371 1 461000 461371 461000 461371 GRX1 orf19.13863|orf6.7650|IPF20674.1|IPF3919.2|Contig4-3089_0003|CA4963|CaJ7.0239|CaO19.6510|CaJ7_0239|CaO19_6510|CaO19.13863|IPF3919 Protein described as glutaredoxin; transcriptionally regulated by iron; expression greater in low iron [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 461556 461844 - ntar_1104 461556 461844 1 461844 461556 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 461628 462335 + orf19.6509 461628 462335 1 461628 462335 461684 462154 orf19.13862|IPF20646.1|IPF3920.1|Contig4-3089_0002|orf6.7651|CA4964|CaJ7.0240|CaO19_6509|CaJ7_0240|TTR12|CaO19.13862|CaO19.6509|IPF3920 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 462059 463232 - orf19.6508 462059 463232 1 463232 462059 463059 462247 orf19.13861|IPF20627.1|IPF3921.2|Contig4-3089_0054|orf6.7652|CA4965|CaJ7.0241|LST7|CaO19.6508|CaO19.13861|CaO19_6508|CaJ7_0241|IPF3921 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr7 463411 464782 + orf19.6507 463411 464782 2 463411|463638 463576|464782 463558 464782 orf19.13860|IPF20594.1|IPF3923.1|Contig4-2803_0010|orf6.7653|CA4966|CaJ7.0243|SPX5|CaO19.13860|CaJ7_0243|CaO19_6507|CaO19.6507|IPF3923 Predicted ORF in Assemblies 19, 20 and 21; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 465023 467256 + orf19.6506 465023 467256 1 465023 467256 465070 467136 orf19.13859|IPF20561.1|IPF3927.2|Contig4-2803_0009|orf6.7654|CA4967|CaJ7.0245|CaO19.6506|CaO19.13859|CaO19_6506|CaJ7_0245|IPF3927 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 467197 467805 - orf19.6503 467197 467805 1 467805 467197 467773 467312 orf19.13856|IPF20659.1|IPF3928.1|Contig4-2803_0007|orf6.7657|CA4968|CaJ7.0247|CaO19.13856|MRP49|CaO19_6503|CaJ7_0247|CaO19.6503|IPF3928 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 468127 469164 + orf19.6502 468127 469164 1 468127 469164 468127 469164 orf19.13855|IPF3930|IPF18613.2|IPF3930.2|Contig4-2803_0006|orf6.3367|orf6.7658|CA4969|CaJ7.0248|CaO19_6502|CaJ7_0248|CaO19.6502 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21; upregulation correlates with clinical development of fluconazole resistance [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 469502 470374 + orf19.6501 469502 470374 1 469502 470374 469502 470374 orf19.13854|IPF3931.2|IPF18151.2|Contig4-2803_0005|orf6.3366|orf6.7659|CA1733|CaJ7.0249|YJU99|CaO19.6501|CaJ7_0249|CaO19_6501|IPF3931 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr7 470039 471798 - orf19.6500 470039 471798 1 471798 470039 471728 470409 ECM42 orf19.13853|IPF20600.1|IPF3933.2|Contig4-2803_0003|orf6.3365|ECM40|CA1732|CaJ7.0250|CaO19.13853|CaO19.6500|CaO19_6500|CaJ7_0250 Putative ornithine acetyltransferase; fungal-specific (no human or murine homolog); Gcn2p-, Gcn4p-regulated; clade-specific gene expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 472190 475863 + orf19.6499 472190 475863 1 472190 475863 472190 475846 orf19.13852|IPF20679.1|IPF8437.2|Contig4-2822_0008|orf6.3364|CA1731|CaJ7.0251|CaO19.13852|CaJ7_0251|CaO19_6499|CaO19.6499|IPF8437 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr7 475876 476974 - orf19.6498 475876 476974 1 476974 475876 476931 475903 orf19.13851|IPF20606.1|IPF8439.1|Contig4-2822_0006|orf6.3363|CA1730|CaJ7.0252|CaO19.6498|CaJ7_0252|CaO19_6498|CaO19.13851|IPF8439 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 477138 477881 - orf19.6496 477138 477881 1 477881 477138 477807 477169 TRS33 orf19.13849|IPF20634.1|IPF8440.1|Contig4-2822_0004|orf6.3361|CA1729|CaJ7.0254|CaO19.13849|CaO19.6496|CaJ7_0254|CaO19_6496|IPF8440 Predicted ORF in Assemblies 19, 20 and 21; constitutive expression independent of MTL or white-opaque status [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 478122 479619 - ntar_1105 478122 479619 1 479619 478122 478701 478534 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 478705 479250 + ntar_1106 478705 479250 1 478705 479250 479083 479250 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 479490 482804 + orf19.6494 479490 482804 1 479490 482804 480373 482487 WHI3 orf19.13847|IPF20559.1|IPF8447.2|Contig4-2822_0002|orf6.3359|CA1728|CaJ7.0255|CaO19_6494|CaJ7_0255|CaO19.13847|WHI4|CaO19.6494 Predicted ORF in Assemblies 19, 20 and 21; induced during infection of murine kidney, compared to growth in vitro; has murine homolog [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 483018 483224 - ntar_1107 483018 483224 1 483224 483018 483224 483057 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 483239 483631 + orf19.6493 483239 483631 1 483239 483631 483239 483631 orf19.13846|IPF8448.2|IPF19356.2|Contig4-2822_0001|orf6.3358|CA1727|CaJ7.0257|CaO19.6493|CaO19_6493|CaJ7_0257|IPF8448 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 483757 485295 - orf19.6492 483757 485295 1 485295 483757 485036 483810 orf19.13845|IPF20604.1|IPF17347.2|orf6.289|CA0044|CaJ7.0258|CaJ7_0258|CaO19_6492|CaO19.13845|CaO19.6492|IPF17347 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 486519 486872 + orf19.6491 486519 486872 1 486519 486872 486519 486872 orf19.13844|IPF20673.1|IPF27698.1|Contig4-1746_0005|orf6.1076|CaJ7.0259|CaO19.13844|CaO19.6491|CaO19_6491|CaJ7_0259 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 487109 487966 + orf19.6489 487109 487966 1 487109 487966 487109 487966 FMP45 orf19.13842|YDL225C|IPF20624.1|IPF6624.2|Contig4-2725_0016|orf6.1074|YDL222C|CA0293|CaJ7.0261|CaO19_6489|CaJ7_0261|CaO19.6489|CaO19.13842|IPF6624 Protein induced during the mating process; mutation confers hypersensitivity to toxic ergosterol analog, and to amphotericin B; alkaline downregulated; repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 489299 491008 + orf19.6488 489299 491008 1 489299 491008 489299 491008 orf19.13841|IPF19855.1|IPF19854.1|Contig4-2725_0013|Contig4-2725_0014|orf6.1018|orf6.1073|CA0292|CaJ7.0262|CaJ7_0262|CaO19_6488|CaO19.6488|IPF19855 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 492240 492731 + orf19.6487 492240 492731 1 492240 492731 492273 492731 IPF19057.2|IPF6620.2|Contig4-2725_0009|orf6.1019|CA6230|CaJ7.0263|LDG2|CaO19_6487|CaJ7_0263|CaO19.6487|IFW1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr7 493961 494419 + orf19.6486 493961 494419 1 493961 494419 493961 494419 LDG3 orf19.13840|IPF20654.1|IPF19071.2|orf6.3709|orf6.1020|CA6229|CaJ7.0264|CaO19.6486|CaJ7_0264|CaO19_6486|IFW2|CA1991|IPF6617.repeat2|IPF6619.1 Predicted ORF in Assemblies 19, 20 and 21; induced upon biofilm formation [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 495607 496065 + orf19.6484 495607 496065 1 495607 496065 495607 496065 orf19.13838|IPF20654.1|IPF6617.2|Contig4-2725_0006|orf6.3709|orf6.3710|CA1992|CaJ7.0266|CaO19_6484|CaJ7_0266|LDG4|CaO19.6484|CaO19.13838|IFW3|IPF6617.repeat1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 496646 497552 + orf19.6482 496646 497552 1 496646 497552 496851 497402 orf19.13836|IPF20644.1|IPF6614.2|orf6.3712|CA1993|CaJ7.0268|CaO19_6482|CaJ7_0268|CaO19.13836|CaO19.6482|IPF6614 Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide in yhb1 mutant; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr7 497779 500061 + orf19.6481 497779 500061 1 497779 500061 497855 499960 YPS7 orf19.13835|IPF20555.1|IPF6613.2|Contig4-2725_0001|orf6.3713|CA1994|CaJ7.0269|CaJ7_0269|CaO19_6481|CaO19.13835|CaO19.6481|IPF6613 Putative aspartic-type endopeptidase with limited ability to degrade alpha pheromone; mutants show increased sensitivity to alpha pheromone [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 500010 501649 - orf19.6480 500010 501649 1 501649 500010 501344 500154 orf19.13834|IPF20608.1|IPF6612.1|Contig4-2725_0017|orf6.3714|CA1995|CaJ7.0270|CaO19.6480|YMD8|CaO19.13834|CaJ7_0270|CaO19_6480|IPF6612 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 501774 502282 - ntar_1108 501774 502282 1 502282 501774 502282 502091 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 502455 505115 + orf19.6479 502455 505115 1 502455 505115 502656 504995 orf19.13833|IPF20545.1|IPF6609.1|Contig4-2536_0003|orf6.3715|CA1996|CaJ7.0271|CaO19_6479|CaJ7_0271|SEC1|CaO19.6479|CaO19.13833 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 504342 504519 - ntar_1109 504342 504519 1 504519 504342 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 504762 504984 - ntar_1110 504762 504984 1 504984 504762 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 505401 510349 + orf19.6478 505401 510349 1 505401 510349 505458 510200 YCF1 orf19.13832|IPF20661.1|IPF6607.2|Contig4-2536_0005|orf6.3716|CA1997|CaJ7.0273|CaO19_6478|CaJ7_0273|CaO19.13832|CaO19.6478 Putative glutathione S-conjugate transporter with similarity to S. cerevisiae Ycf1p; MRP/CFTR-subfamily, ABC transporter family; human neutrophil-induced; oxidative stress-induced via Cap1p; possible association with multidrug resistance [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr7 510222 511651 - orf19.6477 510222 511651 1 511651 510222 511622 510342 orf19.13831|IPF20597.1|IPF6605.2|Contig4-2536_0006|orf6.3717|CA1998|CaJ7.0274|CaO19.13831|CaO19.6477|CaO19_6477|CaJ7_0274|IPF6605 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 511766 514421 - orf19.6476 511766 514421 1 514421 511766 514210 511808 orf19.13830|IPF19513.1|IPF18571.2|Contig4-2536_0007|orf6.3718|orf6.509|CA1999|CaJ7.0275|CaO19.6476|CaJ7_0275|CaO19_6476|IPF19513 Predicted ORF in Assemblies 19, 20 and 21; filament induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 515715 516128 + orf19.6475 515715 516128 1 515715 516128 515715 516128 orf19.13829|IPF20664.1|IPF12659.2|Contig4-2430_0011|orf6.2219|orf6.510|CaJ7.0276|CaO19.6475|CaJ7_0276|CaO19_6475 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 517383 518179 + orf19.6474 517383 518179 1 517383 518179 517537 518040 orf19.13828|IPF20641.1|IPF12662.1|Contig4-2430_0006|orf6.2218|CA0973|CaJ7.0277|CaO19_6474|CaJ7_0277|CaO19.13828|CaO19.6474|IPF12662 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 519022 519700 - orf19.6472 519022 519700 1 519700 519022 519625 519137 CYP1 orf19.13826|IPF20652.1|IPF17713.2|Contig4-1392_0002|Contig4-2430_0002|orf6.2216|CA0972|CaJ7.0279|CPR1|CaO19.13826|CaO19.6472|CaJ7_0279|CaO19_6472 Peptidyl-propyl cis-trans isomerase (PPIase); activity is cyclosporin A sensitive; soluble protein in hyphae; biofilm induced, macrophage-induced protein; downregulated upon treatment of biofilm with farnesol [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 520524 521281 + orf19.6470 520524 521281 1 520524 521281 520556 521113 AHP2 orf19.13824|IPF20642.1|IPF11428.2|Contig4-2613_0012|orf6.2214|CA0971|CaJ7.0281|AHP13|CaO19.6470|CaO19_6470|CaJ7_0281|CaO19.13824|IPF11428 Predicted ORF in Assemblies 19, 20 and 21; macrophage-downregulated gene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 523720 526233 - orf19.6469 523720 526233 1 526233 523720 526233 523720 IPF19294.1|Contig4-2630_0007|orf6.5992|orf6.412|orf6.413|CA0069|CA0070|CaJ7.0282|CaJ7.0283|orf19.6467|orf19.6468|IPF19295.3f Predicted ORF in retrotransposon Tca11 with similarity to the Gag-Pol region of retrotransposons, which encodes nucleocapsid-like protein, reverse transcriptase, protease, and integrase [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 526552 527907 - orf19.6465 526552 527907 1 527907 526552 527907 526552 IPF17991.2|Contig4-2630_0004|orf6.5994|CA3661|CaJ7.0286|CaO19.6465|IPF17991 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 528947 531177 + orf19.6464 528947 531177 1 528947 531177 529027 530880 orf19.13823|IPF17021|IPF11430.2|IPF17021.2|Contig4-2613_0008|Contig4-2613_0010|orf6.2212|orf6.2213|orf6.5995|CA3662|CaJ7.0287|CaO19.6464|CaO19_6464|CaJ7_0287 Predicted ORF in Assemblies 19, 20 and 21; induced upon adherence to polystyrene; oxidative stress-induced via Cap1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 530754 532206 - orf19.6463 530754 532206 1 532206 530754 532174 530897 orf19.13821|IPF18813.2|IPF11432.2|Contig4-2613_0007|orf6.2211|orf6.5996|YJR072|CA3663|CaJ7.0288|CaO19.6463|CaJ7_0288|CaO19_6463|IPF11432 Predicted ORF in Assemblies 19, 20 and 21; putative ortholog of S. cerevisiae Yjr072cp; possibly essential for growth (however, depletion mutant is viable) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 532217 533258 - orf19.6462 532217 533258 2 533258|532884 532977|532217 533134 532257 orf19.13820|IPF20570.1|IPF20640.1|IPF11434.1|IPF11433.1|Contig4-2613_0005|orf6.5997|CaJ7.0289|orf19.6461.1|CA3664|IPF11434|IPF11433.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 533737 534624 + orf19.6461 533737 534624 1 533737 534624 533827 534342 orf19.13819|IPF20643.1|IPF11435.1|Contig4-2613_0002|orf6.5998|CA3666|CaJ7.0290|CaO19.6461|COX20|CaO19.13819|CaO19_6461|CaJ7_0290|IPF11435 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 534858 538384 + orf19.6460 534858 538384 1 534858 538384 534971 538246 orf19.13818|IPF20687.1|IPF16323.2|Contig4-2468_0013|orf6.5999|CA3667|CaJ7.0291|PEX1|CaO19.6460|CaO19_6460|CaJ7_0291|CaO19.13818|IPF16323 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 538211 539412 - orf19.6459 538211 539412 1 539412 538211 539309 538389 DPP3 orf19.13817|IPF20617.1|IPF19996.1|Contig4-2468_0011|orf6.6000|CA3668|CaJ7.0292|CaO19.13817|CaJ7_0292|CaO19_6459|CaO19.6459 Protein similar to S. cerevisiae pyrophosphate phosphatase Dpp1p; required for farnesol biosynthesis; downregulated in response to 17-beta-estradiol, ethynyl estradiol [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 539779 541228 + orf19.6458.1 539779 541228 2 539779|540539 540456|541228 540454 540928 IPF20676.1|IPF19997.1|CA3669|CaJ7.s010|CaJ7_s010|IPF19997 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 541126 543740 - orf19.6457 541126 543740 1 543740 541126 543676 542126 orf19.13815|IPF20578.1|IPF13933.1|Contig4-2468_0005|orf6.6002|CA3671|CaJ7.0294|CaO19.13815|CaO19.6457|CaO19_6457|CaJ7_0294|IPF13933 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 541394 542185 + orf19.6458 541394 542185 1 541394 542185 541394 542185 orf19.13816|IPF20623.1|IPF13934.2|Contig4-2468_0006|orf6.6001|CA3670|CaJ7.0293|CaJ7_0293|CaO19_6458|CaO19.6458|IPF13934 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 544417 544975 - ntar_1111 544417 544975 1 544975 544417 544671 544417 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 545649 547637 + orf19.6456 545649 547637 1 545649 547637 545768 547444 orf19.13814|IPF20584.1|IPF13669.2|Contig4-2374_0008|Contig4-2669_0007|orf6.6003|CA3672|CaJ7.0295|CaJ7_0295|CaO19_6456|CaO19.6456|CaO19.13814|IPF13669 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr7 547533 548419 - orf19.6455 547533 548419 1 548419 547533 548338 547670 orf19.13813|IPF20636.1|IPF13667.2|Contig4-2374_0007|orf6.6004|CA3673|CaJ7.0296|CaO19.6455|CaO19_6455|CaJ7_0296|CaO19.13813|IPF13667 Putative protein of unknown function, transcription is upregulated in clinical isolates from HIV+ patients with oral candidiasis; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 548505 552591 + orf19.6453 548505 552591 1 548505 552591 548612 552553 orf19.11187|orf19.13811|orf19.13812|IPF18687.1|IPF19531.1|IPF19530.1|IPF18311.1|Contig4-2374_0003|Contig4-2374_0004|orf6.2874|orf6.6006|orf6.6005|CA3675|CA3674|CaJ7.0297|CaJ7.0298|orf19.3703|orf19.6454|IPF19529.3f|IPF19529.exon2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr7 552468 553114 - orf19.6452 552468 553114 1 553114 552468 553012 552638 RBP1 orf19.11186|orf19.13810|IPF13665.1|IPF20677.1|IPF8077.2|Contig4-2374_0002|orf6.2875|orf6.6007|CA3676|CaJ7.0299|orf19.3702|CaO19_6452|CaJ7_0299|CaO19.6452|RBP12|CaO19.13810 Peptidyl-prolyl cis-trans isomerase; rapamycin-binding protein; homozygous null mutation confers rapamycin resistance; regulated by Gcn4p; macrophage-induced protein; repressed in response to 3-AT; functional homolog of S. cerevisiae Rbp1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 554244 558944 - orf19.2372 554244 558944 1 558944 554244 558944 554244 orf19.9908|IPF24953.1|IPF29132.1|Contig4-2898_0014|orf6.4027|orf6.4770|orf6.6008|CaO19.2372|POL99|CaO19.9908 Putative Pol protein of retrotransposon Tca2; separated by a stop codon from Gag protein orf19.2371; both likely translated as single polyprotein that includes nucleocapsid-like protein (Gag), reverse transcriptase, protease, and integrase [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 558970 559928 - orf19.2371 558970 559928 1 559928 558970 559928 558975 orf19.9907|IPF24948.1|IPF29129.1|Contig4-2369_0001|orf6.4769|GAG1|CaO19.9907|CaO19.2371 Putative Gag protein of retrotransposon Tca2; separated by a stop codon from Pol protein orf19.2372; both likely translated as single polyprotein that includes nucleocapsid-like protein (Gag), reverse transcriptase, protease, and integrase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr7 560401 562697 + orf19.3701 560401 562697 1 560401 562697 560586 562502 orf19.11185|IPF8075|IPF23571.1|IPF8075.2|Contig4-2964_0008|orf6.2876|CA1396|CaJ7.0304|CaO19_3701|CaJ7_0304|CaO19.11185|CaO19.3701 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 562844 565135 + orf19.3700 562844 565135 1 562844 565135 563076 564965 TOM70 orf19.11184|IPF23570.1|IPF8073.2|Contig4-2568_0001|orf6.2877|CA1397|CaJ7.0305|TOM71|CaO19.3700|CaO19.11184|CaO19_3700|CaJ7_0305|TOM72 Protein described as mitochondrial import receptor [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 565242 566519 + orf19.3699 565242 566519 1 565242 566519 565324 566484 TEP1 orf19.11183|IPF23574.1|IPF19913.1|Contig4-2159_0001|Contig4-2159_0002|orf6.2878|CA1398|CaJ7.0306|CaO19.11183|CaO19.3699|CaJ7_0306|CaO19_3699|IPF19913 Putative protein phosphatase of the PTP family (tyrosine-specific), similar to S. cerevisiae Tep1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 566519 567497 - orf19.3698 566519 567497 1 567497 566519 567256 566576 orf19.11182|IPF23575.1|IPF8069.1|Contig4-2159_0003|orf6.2879|CA1399|CaJ7.0307|CaO19.11182|CaO19.3698|CaO19_3698|CaJ7_0307|IPF8069 Predicted ORF in Assemblies 19, 20 and 21; filament induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 567982 571080 + orf19.3697 567982 571080 1 567982 571080 568048 571029 orf19.11181|IPF23569.1|IPF8067.1|Contig4-2159_0009|orf6.2880|CA1400|CaJ7.0308|CaO19.3697|CaO19_3697|CaJ7_0308|CaO19.11181|IPF8067 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 571166 572086 + orf19.3696 571166 572086 1 571166 572086 571215 571667 TOM22 orf19.11180|IPF18832.2|IPF8066.1|Contig4-1953_0001|orf6.2142|orf6.2881|CA1401|CaJ7.0309|CaO19.11180|CaO19.3696|CaO19_3696|CaJ7_0309 Predicted ORF in Assemblies 19, 20 and 21; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 571793 573243 - orf19.3695 571793 573243 1 573243 571793 573118 571910 orf19.11179|IPF23573.1|IPF8065.2|Contig4-1953_0003|Contig4-1953_0004|orf6.2143|orf6.2882|CA0932|CaJ7.0310|CaO19.3695|EPT1|CaO19_3695|CaJ7_0310 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 573138 573560 + ntar_1112 573138 573560 1 573138 573560 573138 573353 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 574090 574348 + ntar_1113 574090 574348 1 574090 574348 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 575028 575178 - ntar_1114 575028 575178 1 575178 575028 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 585462 587000 + orf19.5191 585462 587000 1 585462 587000 585462 587000 FGR6-1 orf19.12658|IPF22053.1|IPF20089.1|Contig4-1717_0001|orf6.3502|CA1833|CaJ7.0311|CaO19.12658|CaO19.5191|IFV3 Protein lacking an ortholog in S. cerevisiae; member of a family encoded by FGR6-related genes in the RB2 repeat sequence; transposon mutation affects filamentous growth [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 590144 591202 - ntar_1115 590144 591202 1 591202 590144 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 590363 590788 + orf19.5190 590363 590788 1 590363 590788 590363 590788 orf19.12657|IPF22082.1|IPF17727.1|Contig4-1794_0007|Contig4-2965_0002|Contig4-3084_0003|orf6.3501|CA1832|CaJ7.0312|CaO19.12657|CaO19.5190|IPF17727 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 590826 591384 + ntar_1116 590826 591384 1 590826 591384 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 591571 591779 + ntar_1117 591571 591779 1 591571 591779 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 592266 592828 - ntar_1118 592266 592828 1 592828 592266 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 593088 596351 + orf19.5188 593088 596351 1 593088 596351 593140 596220 CHS1 orf19.12655|CHS1A|IPF22109.1|IPF6129.2|Contig4-2406_0005|Contig4-2406_0006|orf6.3499|CA1831|CaJ7.0315|CaJ7_0315|CaO19_5188|CaO19.5188|CaO19.12655 Chitin synthase; essential; required for primary septum synthesis in yeast-form cells and hyphae; one of multiple chitin synthases; enzymatically activated by proteolytic processing; complements defects of S. cerevisiae chs1 or chs2 mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 596425 597979 + orf19.5184 596425 597979 1 596425 597979 596459 597940 orf19.12651|orf19.12652|IPF22062.1|IPF22072.1|IPF17178.1|IPF17177.2|Contig4-2406_0001|Contig4-2406_0002|orf6.3495|orf6.3496|CA1829|CA1830|CaJ7.0317|orf19.5185|CaO19_5184|CaJ7_0317|IPF17177.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 597938 601154 - orf19.5182 597938 601154 1 601154 597938 601113 597997 POL3 orf19.12649|orf19.12650|POLIII|orf6.546|orf6.3494|CA0107|CaJ7.0319|orf19.5183|CDC2 Large subunit of DNA polymerase III; partially complements defects of an S. cerevisiae cdc2 mutant; differing reports about periodic (G1/S) or non-periodic mRNA expression through cell cycle [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 601528 604918 + orf19.5181 601528 604918 1 601528 604918 601548 604793 NIK1 orf19.12648|COS1|COS-1|IPF22104.1|IPF19235.2|orf6.547|orf6.6955|CA0108|CaJ7.0320|HIK1|CA4415|HIK1.3eoc|IPF11890.1|HIK1.5eoc|IPF19235.1 Histidine kinase involved in a two-component signaling pathway that regulates cell wall biosynthesis; required for wild-type virulence in mouse systemic infection but not for wild-type growth or drug sensitivity/resistance [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 604653 604849 - ntar_1119 604653 604849 1 604849 604653 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 604966 605135 - ntar_1120 604966 605135 1 605135 604966 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 605347 606367 + orf19.5180 605347 606367 1 605347 606367 605347 606078 PRX1 orf19.12647|IPF22066.1|IPF11888.1|YBL064|Contig4-2258_0001|orf6.6956|CA4416|CaJ7.0321|YBL64|CaO19.5180|CaO19.12647|CaJ7_0321|CaO19_5180|IPF11888 Protein described as a putative cysteine peroxidase; transcriptionally induced by interaction with macrophage; fluconazole induced; Fkh2p-downregulated; caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr7 605443 605747 - ntar_1121 605443 605747 1 605747 605443 605747 605487 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 606792 607186 - ntar_1122 606792 607186 1 607186 606792 607186 606971 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 607195 607816 + ntar_1123 607195 607816 1 607195 607816 607195 607365 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 607254 607931 - ntar_1124 607254 607931 1 607931 607254 607732 607589 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 609378 609979 + ntar_1125 609378 609979 1 609378 609979 609594 609791 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 609420 610811 - orf19.5179 609420 610811 1 610811 609420 610811 609420 LIP5 orf19.12646|LIP2-3|IPF22057.1|IPF5395.2|Contig4-1845_0002|orf6.6957|CA4417|CaJ7.0322|CaJ7_0322|CaO19_5179|CaO19.12646|CaO19.5179 Secreted lipase, member of differentially expressed lipase gene family with possible roles in nutrition and acidic microenvironment; LIP5 and LIP8 expressed at all stages of mucosal and systemic infection; affects filamentous growth [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 610570 610903 + ntar_1126 610570 610903 1 610570 610903 610570 610731 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 612057 613750 - orf19.5178 612057 613750 1 613750 612057 613720 612167 ERG5 orf19.12645|IPF22052.1|IPF5398.1|Contig4-2348_0004|orf6.6958|CA4418|CaJ7.0323|CaO19.12645|CaO19.5178|CaO19_5178|CaJ7_0323 Putative C-22 sterol desaturase; fungal C-22 sterol desaturases are cytochrome P450 enzymes of ergosterol biosynthesis, catalyze formation of the C-22(23) double bond in the sterol side chain; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 614791 617191 + orf19.5177 614791 617191 1 614791 617191 614850 616880 orf19.12644|IPF22043.1|IPF5401.2|Contig4-2348_0001|Contig4-2348_0002|orf6.6959|CA4419|CaJ7.0324|CaJ7_0324|CaO19_5177|LPF36|CaO19.5177|CaO19.12644|IFA6 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr7 617526 621151 - orf19.5175 617526 621151 1 621151 617526 621061 617642 orf19.12642|IPF22097.1|IPF5404.2|Contig4-3092_0052|orf6.6961|CA4420|CaJ7.0325|CaO19.5175|SSM4|CaO19.12642|CaO19_5175|CaJ7_0325 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 621270 621899 - orf19.5174 621270 621899 1 621899 621270 621841 621341 TAF19 orf19.12641|IPF22077.1|IPF5405.2|Contig4-3092_0047|orf6.6962|CA4421|CaJ7.0327|CaO19.12641|TAF13|CaO19.5174|CaJ7_0327|CaO19_5174 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to amphotericin B [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 622142 623503 - orf19.5172 622142 623503 1 623503 622142 623503 622142 LIP9 orf19.12639|orf19.12640|IPF22071.1|IPF22065.1|IPF5407.2|IPF5406.2|Contig4-3092_0045|orf6.6964|orf6.6963|CA4423|CA4422|CaJ7.0329|orf19.5173|LIP9.5f|LIP9.exon1 [NOT TRANSCRIBED?] Secreted lipase, member of a lipase gene family whose members are expressed differentially in response to carbon source and during infection; may have a role in nutrition and/or in creating an acidic microenvironment [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 624549 627536 - orf19.5171 624549 627536 1 627536 624549 627319 624686 PMT1 orf19.12638|IPF22034.1|IPF5408.1|Contig4-3092_0043|orf6.6965|CA4424|CaJ7.0330|CaO19.12638|CaO19.5171|CaO19_5171|CaJ7_0330 Protein mannosyltransferase, required for virulence in mouse systemic infection and for adhesion to epithelial cells; has a role in hyphal growth and drug sensitivity; Als1p, Sec20p, Kre9p, Pir1p are substrates; one of 5 PMT family members [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 629342 632858 + orf19.5170 629342 632858 1 629342 632858 629811 632771 ENA21 orf19.12637|IPF22107.1|IPF5411.2|ENA21.3|Contig4-3092_0037|orf6.6966|CA4425|CaJ7.0331|CaO19.5170|ENA2|CaO19.12637|CaJ7_0331|CaO19_5170|ENA21.3f Predicted ORF similar to S. cerevisiae sodium transporters Ena1p and Ena5p; Gcn4p-regulated; flucytosine, amphotericin B, or ketoconazole-induced; osmotic stress-induced; overlaps orf19.5170.1, which is annotated as a blocked reading frame [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chr7 633385 635333 + orf19.5169 633385 635333 1 633385 635333 633447 635168 orf19.12636|IPF22048.1|IPF5587.2|Contig4-3092_0034|orf6.6967|CA4426|CaJ7.0332|CaO19.12636|AMD22|CaJ7_0332|CaO19_5169|AMD21|CaO19.5169 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 635134 636615 - orf19.5168 635134 636615 1 636615 635134 636587 635283 orf19.12635|IPF22056.1|IPF5584.1|Contig4-3092_0033|orf6.6968|CA4427|CaJ7.0333|CaO19.5168|CaO19_5168|CaJ7_0333|CaO19.12635|IPF5584 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 636668 639113 - orf19.5167 636668 639113 1 639113 636668 639065 636762 IFM1 orf19.12634|IPF22038.1|IPF5581.2|Contig4-3092_0031|Contig4-3092_0032|orf6.6969|CA4428|CaJ7.0334|CaO19.5167|CaJ7_0334|CaO19_5167 Transcription is regulated by Nrg1p, Mig1p, and Tup1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 639180 640801 - orf19.5166 639180 640801 1 640801 639180 640747 639227 DBF4 orf19.12633|IPF22054.1|IPF5578.1|Contig4-3092_0030|orf6.6970|CA4429|CaJ7.0336|CaJ7_0336|CaO19_5166|CaO19.5166|CaO19.12633 Predicted ORF in Assemblies 19, 20 and 21; macrophage/pseudohyphal-repressed; cell-cycle regulated periodic mRNA expression; S. cerevisiae ortholog is not cell-cycle regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 641077 642539 - orf19.5165 641077 642539 1 642539 641077 642434 641307 orf19.12632|IPF22060.1|IPF5577.2|Contig4-3092_0029|orf6.6971|CA4430|CaJ7.0337|CaO19.12632|CaO19_5165|CaJ7_0337|CaO19.5165|IPF5577 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 642599 644678 + orf19.5164 642599 644678 1 642599 644678 642621 644375 ECM39 orf19.12631|orf6.6972|IPF22045.1|IPF5575.2|Contig4-3092_0028|CA4431|CaJ7.0338|CaO19.5164|CaO19_5164|CaJ7_0338|CaO19.12631 Putative mannosyltransferase; similar to S. cerevisiae Ecm39p, which has a role in Calcofluor white resistance; predicted Kex2p substrate; has HKEXRF motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 644350 647805 - orf19.5163 644350 647805 1 647805 644350 647745 644383 SFI1 orf19.12630|IPF22102.1|IPF5574.2|Contig4-3092_0026|Contig4-3092_0027|orf6.6973|CA4432|CaJ7.0339|CaO19_5163|CaJ7_0339|CaO19.12630|CaO19.5163|IPF5574 Predicted ORF in Assemblies 19, 20 and 21; essential for growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 647887 652166 + orf19.5162 647887 652166 1 647887 652166 648125 652087 BCK1 orf19.12629|IPF22091.1|IPF5572.2|Contig4-3092_0024|orf6.6974|CA4433|CaJ7.0340|CaO19.12629|CaO19.5162|CaO19_5162|CaJ7_0340 Predicted ORF in Assemblies 19, 20 and 21; similar to S. cerevisiae Bck1p MAP kinase kinase kinase of cell integrity pathway [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr7 652068 652652 - orf19.5161 652068 652652 1 652652 652068 652621 652139 orf19.12628|IPF22081.1|IPF5569.2|Contig4-3092_0022|orf6.6975|CA4434|CaJ7.0341|MRPL49|CaO19.5161|CaO19_5161|CaJ7_0341|CaO19.12628 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 653008 656460 + orf19.5160 653008 656460 1 653008 656460 653625 656210 orf19.12627|IPF22035.1|IPF5567.2|Contig4-3092_0018|orf6.6976|YJL098|CA4435|CaJ7.0342|CaJ7_0342|CaO19_5160|SAP185|CaO19.12627|CaO19.5160|IPF5567|SAP190 Predicted ORF in Assemblies 19, 20 and 21; similar to S. cerevisiae Sap185p and Sap190p, which are involved in regulation of the cell-cycle phosphatase Sit4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 656200 657540 - orf19.5159 656200 657540 1 657540 656200 657444 656410 orf19.12626|IPF22061.1|IPF13868.2|Contig4-3092_0015|orf6.6977|YNL191|CA4436|CaJ7.0343|CaO19.5159|CaO19.12626|IPF13868 Predicted ORF in Assemblies 19, 20 and 21; similarity to S. cerevisiae Ynl191p; similar to amidophosphoribosyl transferases [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 657807 658725 + orf19.5158 657807 658725 1 657807 658725 658048 658566 orf19.12625|IPF22074.1|IPF13867.2|Contig4-3092_0013|orf6.6978|YKR049|CA4437|CaJ7.0344|CaO19_5158|CaJ7_0344|CaO19.12625|CaO19.5158|IPF13867 Protein with slight similarity to a human gene associated with colon cancer and to orf19.5158; regulated by Gcn4p, Cyr1p; induced in response to amino acid starvation (3-aminotriazole treatment); macrophage-induced protein, macrophage-downregulated gene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 658216 658477 - ntar_1127 658216 658477 1 658477 658216 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 658743 659399 + orf19.5157 658743 659399 1 658743 659399 658783 659394 orf19.12624|IPF22068.1|IPF13866.1|Contig4-3092_0012|orf6.6979|YJL097A|CA4438|CaJ7.0345|CaO19.12624|TPL2|CaO19.5157|CaJ7_0345|CaO19_5157|IPF13866 Predicted ORF in Assemblies 19, 20 and 21; hsix putative membrane-spanning regions; similar to S. cerevisiae Yjl097p, which is required for growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 658911 659374 - ntar_1128 658911 659374 1 659374 658911 659042 658911 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 659418 660355 + orf19.5156 659418 660355 1 659418 660355 659536 660138 orf19.12623|IPF22075.1|IPF13865.1|Contig4-3092_0011|orf6.6980|YJL097B|CA4439|CaJ7.0346|CaJ7_0346|CaO19_5156|CaO19.12623|TPL1|CaO19.5156|IPF13865 Predicted ORF in Assemblies 19, 20 and 21; has six putative membrane-spanning regions; similar to S. cerevisiae Yjl097p, which is required for growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 659953 662574 - orf19.5155 659953 662574 1 662574 659953 662425 660140 CHS6 orf19.12622|IPF22047.1|IPF13864.2|Contig4-3092_0010|orf6.5943|orf6.6981|CA4440|CaJ7.0348|CaO19.5155|CaJ7_0348|CaO19_5155|IPF13864|IPF13864.1 Protein with tetratricopeptide repeats (TPRs); similar to S. cerevisiae Chs6p, which has role in localization of chitin synthase; decreased mRNA abundance observed in cyr1 homozygous mutant hyphae [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 662578 667941 - orf19.5148 662578 667941 1 667941 662578 667810 662738 CYR1 orf19.12615|orf19.12617|CDC35|IPF12336.2|IPF12339.2|IPF12335.3|IPF28127.1|IPF28142.1|Contig4-3092_0006|Contig4-3092_0007|orf6.481|orf6.5946|orf6.5948|CA6295|CA6309|CA3625|CaJ7.0349|orf19.5150|orf19.5151|CYR1.5f Adenylyl cyclase; mutant lacks cAMP; required for mucosal or systemic infection in mice; hyphal growth defect of mutant is rescued by exogenous cAMP; role in macrophage sensitivity, apoptosis; in pathway downstream of Ras1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 669534 671638 + orf19.5147 669534 671638 2 669534|669730 669654|671638 669600 671519 orf19.12613|IPF18318.1|IPF12332.2|Contig4-2330_0005|Contig4-3092_0001|orf6.5950|CA3627|CaJ7.0356|CaJ7_0356|CaO19_5147|CaO19.5147|IPF18318 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 671539 672892 - orf19.5145 671539 672892 1 672892 671539 672892 671645 SSP96 orf19.12611|IPF18317.1|IPF8125.1|Contig4-2330_0004|orf6.258|orf6.5952|orf6.5953|CA3629|CaJ7.0357|CaJ7_0357|CaO19_5145|CaO19.5145|IPF18316|CA3628|IPF18316.3f|IPF18316.5f|IPF18316.1 Predicted ORF in Assemblies 19, 20 and 21; has monooxygenase-like flavin-binding region; induced upon biofilm formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr7 675368 676381 + orf19.5144 675368 676381 1 675368 676381 675515 676195 PGA28 orf19.12609|orf6.311|IPF8129.2|IPF19345.2|Contig4-2330_0001|orf6.5954|CA3630|CaJ7.0358|CaJ7_0358|CaO19_5144|CaO19.5144|IPF8129 Protein similar to S. cerevisiae Wsc2p, which has roles in stress- and cell-wall-related processes; predicted Kex2p substrate; putative GPI-anchored protein [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 676798 678298 + orf19.5143 676798 678298 1 676798 678298 676831 678033 orf19.12608|IPF8130.2|IPF19344.2|orf6.312|orf6.5955|CA3631|CaJ7.0359|CaJ7_0359|CaO19_5143|CaO19.5143|TIM54 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 677923 678707 - orf19.5142 677923 678707 1 678707 677923 678680 678102 DFR1 orf19.12607|IPF22076.1|IPF8131.1|Contig4-2489_0001|orf6.5956|CA3632|DHFR|CaJ7.0360|CaO19.5142|CaO19.12607|CaJ7_0360|CaO19_5142 Dihydrofolate reductase; trimethoprim resistant; DHFR reduces 7,8-dihydrofolate to 5,4,7,8-tetrahydrofolate; binds NADPH; target of drugs that selectively inhibit the fungal enzyme rather than the human enzyme [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 679378 681588 + orf19.5141 679378 681588 1 679378 681588 679378 681549 orf19.12606|IPF22041.1|IPF8136.2|Contig4-2489_0003|orf6.5957|CA3633|CaJ7.0361|CaO19.12606|LPF35|CaO19.5141|CaO19_5141|CaJ7_0361|IFA19 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr7 682335 684422 + orf19.5140 682335 684422 1 682335 684422 682335 684422 orf19.12605|IPF22042.1|IPF8138.2|Contig4-2489_0004|orf6.5958|CA3634|CaJ7.0362|LPF34|CaO19.5140|CaJ7_0362|CaO19_5140|CaO19.12605|IFA25 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr7 685062 687520 + orf19.5139 685062 687520 1 685062 687520 685158 687395 orf19.12604|IPF22040.1|IPF8140.2|orf6.5959|CA3635|CaJ7.0364|CaO19_5139|CaJ7_0364|LPF33|CaO19.5139|CaO19.12604|IFA20 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 687901 690466 + orf19.5138 687901 690466 1 687901 690466 687957 690230 IFA21 orf19.12603|IPF16529.2|IPF28124.1|Contig4-2447_0019|orf6.5960|CA3636|CaJ7.0365|CaJ7_0365|CaO19_5138|CaO19.5138|LPF32 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 690984 692202 - orf19.5137.1 690984 692202 3 692202|692063|691850 692202|692015|690984 692061 691430 HHO1 IPF22037.1|IPF19995.1|Contig4-2447_0016|CaJ7.0366 Protein described at histone H1; farnesol regulated [label_first_exon=CGD label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chr7 692252 692629 - orf19.5137 692252 692629 1 692629 692252 692629 692252 orf19.12602|IPF22078.1|IPF9256.2|Contig4-2447_0012|orf6.5961|CaJ7.0367|CaO19.12602|CaO19_5137|CaJ7_0367|CaO19.5137 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 692646 693341 + ntar_1129 692646 693341 1 692646 693341 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 693219 694526 - orf19.5136 693219 694526 1 694526 693219 694157 693471 orf19.12601|IPF22064.1|IPF9255.2|Contig4-2447_0008|orf6.5962|CA3637|CaJ7.0368|CaO19_5136|CaJ7_0368|CaO19.12601|CaO19.5136|IPF9255 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 694546 694921 + ntar_1130 694546 694921 1 694546 694921 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 694847 695470 - ntar_1131 694847 695470 1 695470 694847 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 695616 696915 + orf19.5134 695616 696915 1 695616 696915 695648 696805 orf19.12599|IPF22059.1|IPF9252.2|Contig4-2447_0001|orf6.5964|CA3638|CaJ7.0370|CaO19.12599|CaO19.5134|CaJ7_0370|CaO19_5134|IPF9252 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 696818 700360 - orf19.5133 696818 700360 1 700360 696818 700360 697043 ZCF29|orf19.12598|IPF22103.1|IPF9251.2|orf6.5965|CA3639|CaJ7.0371|CaO19_5133|CaJ7_0371|CaO19.5133|CaO19.12598|IPF9251 Predicted zinc-finger protein of unknown function [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 700597 700977 - orf19.5132 700597 700977 1 700977 700597 700977 700597 orf19.12597|IPF22088.1|IPF28134.1|orf6.5966|CaJ7.0372|CaO19.5132|CaJ7_0372|CaO19_5132|CaO19.12597 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 701476 702637 - ntar_1132 701476 702637 1 702637 701476 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 702953 705597 + orf19.5131 702953 705597 1 702953 705597 703314 705476 orf19.12596|IPF9245.3|IPF16320.2|Contig4-2185_0005|orf6.3400|orf6.5967|CA1754|CaJ7.0373|CaO19.12596|CaO19_5131|CaJ7_0373|CaO19.5131|IPF16320 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 705474 707402 - orf19.5130 705474 707402 1 707402 705474 707309 705627 PDI1 orf19.12595|IPF22050.1|IPF16217.2|Contig4-2185_0004|orf6.3401|CA1755|CaJ7.0374|CaJ7_0374|CaO19_5130|CaO19.5130|CaO19.12595 Protein described as protein disulfide-isomerase; antigenic in human; soluble protein in hyphae; transcription is induced upon filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 707959 709317 - orf19.5129 707959 709317 1 709317 707959 709164 708478 orf19.12594|IPF22063.1|IPF14562.1|Contig4-2185_0008|orf6.3402|CA1756|CaJ7.0375|PMP4|CaO19.12594|CaO19_5129|CaJ7_0375|CaO19.5129|IPF14562 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 710455 713114 + orf19.5126 710455 713114 1 710455 713114 710719 711912 orf19.12591|orf19.12593|IPF22069.1|IPF14561.3|IPF14556.2|IPF14559.1|Contig4-1627_0002|Contig4-1627_0005|orf6.37|orf6.3405|orf6.3403|CA1758|CA1757|CaJ7.0377|CaJ7.0378|orf19.5128|IPF14559.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 713372 715230 - orf19.5125 713372 715230 1 715230 713372 715230 713515 orf19.12590|IPF22049.1|IPF14744.2|Contig4-2402_0003|orf6.3406|CA1759|CaJ7.0379|CaO19_5125|CaJ7_0379|CaO19.12590|CaO19.5125|IPF14744 Predicted ORF in Assemblies 19, 20 and 21; expression regulated during planktonic growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr7 716449 718420 - orf19.5124 716449 718420 1 718420 716449 718154 716736 RBR3 orf19.12589|orf19.8926|orf6.1159|IFF1|IPF25998.1|IPF16164.3|IPF16302.3|IPF17914.3|Contig4-2402_0004|orf6.3408|orf6.3407|CA0344|CA1760|CaJ7.0381|orf19.5123|orf19.1346|CaO19.5124|IPF17914.3eoc|IPF17914.2 Cell wall protein; expression is repressed by Rim101p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 718151 719185 - ntar_1133 718151 719185 1 719185 718151 719185 718151 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 718686 720815 - ntar_1134 718686 720815 1 720815 718686 720815 718686 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 720467 721847 + ntar_1135 720467 721847 1 720467 721847 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 722685 722907 + ntar_1136 722685 722907 1 722685 722907 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 727350 729316 + ntar_1137 727350 729316 1 727350 729316 727667 727795 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 727502 728884 - orf19.1345 727502 728884 1 728884 727502 728884 727502 LIP8 orf19.8925|orf6.2643|IPF7914.2|IPF29487.1|Contig4-3068_0044|CA1241|CaJ7.0382|CaO19_1345|CaJ7_0382|CaO19.1345 Secreted lipase, member of a differentially expressed lipase gene family with possible roles in nutrition and/or in creating an acidic microenvironment; LIP5 and LIP8 are expressed at all stages of both mucosal and systemic infection [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 729045 730623 - ntar_1138 729045 730623 1 730623 729045 730211 730014 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 730787 731111 - ntar_1139 730787 731111 1 731111 730787 731111 730923 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 730977 732486 + orf19.1344 730977 732486 1 730977 732486 731671 732486 orf19.8924|IPF26000.1|IPF19908.1|Contig4-3068_0038|Contig4-3068_0040|orf6.2644|CA1242|CaJ7.0383|CaO19.1344|CaO19.8924|CaJ7_0383|CaO19_1344|IPF19908 Predicted ORF in Assemblies 19, 20 and 21; fluconazole-induced; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=C scenario_last_exon=C] Ca21chr7 732615 735847 - orf19.1343 732615 735847 1 735847 732615 735818 732660 orf19.8923|IPF7922.2|IPF17576.2|Contig4-3068_0036|orf6.1345|orf6.2645|CA1243|CaJ7.0384|CaJ7_0384|CaO19_1343|SIN4|CaO19.1343|IPF7922 Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 736027 737619 - orf19.1342 736027 737619 1 737619 736027 737569 736088 SHM1 orf19.8922|orf6.1344|IPF19725.2|IPF7924.2|Contig4-3068_0034|orf6.2646|CA0433|CaJ7.0385|CaJ7_0385|CaO19_1342|CaO19.1342 Mitochondrial serine hydroxymethyltransferase; complements the glycine auxotrophy of an S. cerevisiae shm1 null shm2 null gly1-1 triple mutant; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 737647 738804 - orf19.1341 737647 738804 1 738804 737647 738804 737848 PRR2 orf19.8921|IPF25999.1|IPF7926.1|Contig4-3068_0031|orf6.1343|CA0432|CaJ7.0386|CaO19.1341|CaJ7_0386|CaO19_1341|IPF7926 Predicted ORF in Assemblies 19, 20 and 21; mutation confers resistance to 5-fluorocytosine (5-FC) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 738203 738788 + ntar_1140 738203 738788 1 738203 738788 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 738895 739940 - orf19.1340 738895 739940 1 739940 738895 739871 738942 orf19.8920|IPF18538.2|IPF7927.1|Contig4-3068_0030|orf6.1342|CA0431|CaJ7.0387|CaO19_1340|CaJ7_0387|CaO19.1340|IPF7927 Predicted ORF in Assemblies 19, 20 and 21; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 740596 742506 + orf19.1339 740596 742506 1 740596 742506 740688 742316 CPY1 orf19.8919|PRC1|IPF18540.1|IPF7928.2|Contig4-3068_0029|orf6.1341|orf6.3892|CA0430|CaJ7.0388|CaO19.1339|CaO19_1339|CaJ7_0388|CA2122|CPY1.3f Carboxypeptidase Y; transcriptionally regulated at yeast-hyphal transition or macrophage response; upregulated in the presence of human neutrophils; regulated by Gcn2p and Gcn4p; putative N-glycosylation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 742328 743704 - orf19.1338 742328 743704 1 743704 742328 743668 742574 orf19.8918|IPF7930.1|IPF19386.2|Contig4-3068_0028|orf6.3891|CA2121|CaJ7.0389|CaO19_1338|CaJ7_0389|CaO19.8918|CaO19.1338|IPF7930 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 744260 744964 + orf19.1336.2 744260 744964 1 744260 744964 744395 744694 IPF26004.1|IPF8016.2|CA0034|IPF8016 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 744757 745678 - orf19.1336 744757 745678 1 745678 744757 745555 744935 PUP3 orf19.8916|IPF8017.2|IPF8018.1|Contig4-3068_0025|orf6.224|orf6.3889|CA2120|CaJ7.0390|CaO19.1336|CaJ7_0390|CaO19_1336 Predicted ORF in Assemblies 19, 20 and 21; macrophage/pseudohyphal-repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 745807 749072 - orf19.1335 745807 749072 1 749072 745807 749033 745845 orf19.8915|IPF8020.2|IPF29491.1|Contig4-3068_0020|Contig4-3068_0022|Contig4-3068_0024|orf6.223|orf6.3888|CA2119|CaJ7.0392|MTR4|CaO19.1335|CaO19_1335|CaJ7_0392|CaO19.8915 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 749240 752127 - orf19.1334 749240 752127 1 752127 749240 751269 749305 orf19.8914|IPF25991.1|IPF8024.2|Contig4-3068_0019|orf6.3887|CA2118|CaJ7.0393|CaO19.8914|CaO19.1334|CaJ7_0393|CaO19_1334|IPF8024 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction); transcription is repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 753719 755842 - orf19.1333 753719 755842 1 755842 753719 755677 753848 SNG3 orf19.8913|IPF25995.1|IPF8025.2|Contig4-3068_0011|orf6.3886|CA2117|CaJ7.0394|CaO19_1333|CaJ7_0394|CaO19.1333|CaO19.8913 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to toxic ergosterol analog; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 756530 758560 + orf19.1332 756530 758560 1 756530 758560 756801 758462 SNG4 orf19.8912|IPF25997.1|IPF8028.1|Contig4-3068_0008|orf6.3885|CA2116|CaJ7.0395|CaO19.8912|CaJ7_0395|CaO19_1332|CaO19.1332 Predicted ORF in Assemblies 19, 20 and 21; transcriptionally activated by Mnl1p under weak acid stress; shows Mob2p-dependent hyphal regulation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 758285 760097 - orf19.1331 758285 760097 1 760097 758285 759975 758557 HSM3 orf19.8911|IPF8030.1|IPF19088.2|Contig4-3068_0006|orf6.3884|orf6.958|CA2115|CaJ7.0396|CaO19_1331|CaJ7_0396|CaO19.1331|CaO19.8911|IPF8030 Protein not essential for viability; similar to S. cerevisiae Hsm3p, which may be involved in DNA mismatch repair [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 762247 764168 + orf19.1330 762247 764168 1 762247 764168 762348 764168 orf19.8910|IPF25994.1|IPF15703.1|orf6.4357|orf6.959|orf6.6812|CA0240|CaJ7.0397|CaO19.8910|LPF15|CaO19.1330|IFB3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr7 765240 766051 + orf19.6704 765240 766051 1 765240 766051 765240 765917 orf19.8909|orf19.13996|IPF26001.1|IPF15704.2|IPF20486.1|IPF6649.2|Contig4-1873_0005|orf6.960|orf6.6813|CA4304|CaJ7.0398|orf19.1329|LPF44|CaO19.6704|CaO19.13996|IPF6649 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr7 770415 774330 + orf19.6705 770415 774330 1 770415 774330 771047 774184 orf19.13997|IPF20496.1|IPF6654.2|Contig4-2413_0004|orf6.6814|YBL60|CA4305|CaJ7.0399|CaO19.13997|CaO19_6705|CaJ7_0399|CaO19.6705|IPF6654 Putative guanyl nucleotide exchange factor with Sec7 domain, required for normal filamentous growth; transcriptionally regulated upon yeast-hyphal switch; filament induced; regulated by Nrg1p, Tup1p, Mob2p; mRNA binds to She3p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr7 774791 777460 + orf19.6706 774791 777460 1 774791 777460 774942 777272 GYP7 orf19.13998|IPF20471.1|IPF6656.2|Contig4-2413_0003|orf6.6815|CA4306|CaJ7.0400|CaO19.6706|CaO19_6706|CaJ7_0400|CaO19.13998 Predicted ORF in Assemblies 19, 20 and 21; similar to S. cerevisiae Gyp7p (GTPase-activating protein for Ypt1p); caspofungin-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 776028 777256 - ntar_1141 776028 777256 1 777256 776028 776527 776276 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 777537 779077 + orf19.6707 777537 779077 1 777537 779077 777712 778878 orf19.13975|orf19.13999|IPF17904.3|IPF20482.1|IPF20013.1|Contig4-1469_0004|orf6.6792|orf6.6816|CA4285|CA4307|CaJ7.0401|orf19.6683|CaO19.13999|CaO19.6707|IPF20013 Predicted ORF in Assemblies 19, 20 and 21; transcription is repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 779616 780686 + orf19.6684 779616 780686 1 779616 780686 779738 780472 PNC1 orf19.13976|orf19.14000|IPF20488.1|IPF20011.1|IPF20491.1|IPF6660.2|IPF6660|Contig4-3088_0002|orf6.6793|orf6.6817|CA4286|CA4308|CaJ7.0402|orf19.6708|IPF20011.5f Putative nicotinamidase, involved in NAD salvage pathway; decreased transcription is observed in an azole-resistant strain that overexpresses MDR1 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 780397 781351 - orf19.6685 780397 781351 1 781351 780397 781300 780500 ISY1 orf19.13977|IPF20485.1|IPF6662.2|Contig4-3088_0005|orf6.6794|CA4288|CaJ7.0403|CaO19_6685|CaJ7_0403|CaO19.6685|CaO19.13977|IPF6662 Predicted ORF in Assemblies 19, 20 and 21; mutation confers resistance to 5-fluorocytosine (5-FC) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 781498 783944 - orf19.6686 781498 783944 1 783944 781498 783847 781595 ENP2 orf19.13978|IPF2618.3|IPF6665.2|Contig4-3088_0006|Contig4-3088_0008|orf6.383|orf6.6795|CA4289|CaJ7.0404|CaO19.6686|CaJ7_0404|CaO19_6686|IPF6665 Predicted ORF in Assemblies 19, 20 and 21; essential; S. cerevisiae ortholog is essential; heterozygous mutation confers resistance to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 784229 786232 - orf19.6687 784229 786232 1 786232 784229 786232 784229 orf19.13979|IPF6666.3|IPF2617.1|Contig4-3088_0010|orf6.382|orf6.6796|CA4290|CaJ7.0405|CaO19_6687|CaJ7_0405|CaO19.6687|IPF2617 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 789512 790492 + orf19.6688 789512 790492 1 789512 790492 789512 790492 orf19.13980|IPF20483.1|IPF2615.1|IPF2615|Contig4-3088_0015|orf6.6797|CA4291|CaJ7.0406|CaJ7_0406|CaO19_6688|CaO19.13980|CaO19.6688 Decreased transcription is observed upon benomyl treatment or in an azole-resistant strain that overexpresses MDR1 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr7 792029 793747 + orf19.6689 792029 793747 1 792029 793747 792083 793489 ARG4 orf19.13981|orf6.6798|ARG57|IPF20481.1|IPF2612.2|Contig4-3088_0016|CA4292|CaJ7.0407|CaJ7_0407|CaO19_6689|CaO19.13981|CaO19.6689 Argininosuccinate lyase, catalyzes the final step in the arginine biosynthesis pathway; alkaline downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 793510 796160 - orf19.6690 793510 796160 1 796160 793510 795818 793740 orf19.13982|IPF20473.1|IPF2611.1|orf6.6799|CA4293|CaJ7.0408|CaO19.6690|LPF42|CaJ7_0408|CaO19_6690|CaO19.13982|IFA8 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr7 796730 798896 - orf19.6691 796730 798896 1 798896 796730 798693 796834 orf19.13983|IPF20476.1|IPF2610.2|Contig4-3088_0020|orf6.6800|CA4294|CaJ7.0409|ERC1|CaO19_6691|CaJ7_0409|MTE1|CaO19.13983|CaO19.6691 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 800227 802939 + orf19.6692 800227 802939 1 800227 802939 800431 802701 MNN7 orf19.13984|IPF20472.1|IPF2606.1|Contig4-3088_0024|orf6.6801|CA4295|CaJ7.0410|MNN26|CaO19.6692|CaO19_6692|CaJ7_0410|CaO19.13984 Protein described as mannosyltransferase; identified in detergent-resistant membrane fraction (possible lipid raft component); predicted N-terminal acetylation and transmembrane helix [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 802889 806381 - orf19.6693 802889 806381 1 806381 802889 806381 802950 orf19.13985|IPF20494.1|IPF2605.1|Contig4-3088_0028|orf6.6802|CA4296|CaJ7.0411|CaO19.13985|CaJ7_0411|CaO19_6693|CaO19.6693|IPF2605 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr7 806621 808726 - orf19.6694 806621 808726 1 808726 806621 808696 806717 orf19.13986|IPF20475.1|IPF2603.1|Contig4-3088_0029|orf6.6803|CA4297|CaJ7.0414|CaO19_6694|CaJ7_0414|CaO19.6694|CaO19.13986|IPF2603 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 808894 809549 - orf19.6696 808894 809549 2 809549|809152 809253|808894 809485 809122 TIM9 orf19.13988|IPF20492.1|IPF2599.1|Contig4-3088_0031|orf6.6805|CA4298|CaJ7.0415|CaO19.13988|CaJ7_0415|CaO19_6696|CaO19.6696 Predicted ORF in Assemblies 19, 20 and 21; transcription is upregulated in both intermediate and mature biofilms [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 809701 811283 - orf19.6698 809701 811283 1 811283 809701 811253 809784 orf19.13990|IPF20480.1|IPF2598.1|Contig4-3088_0032|orf6.6807|CA4299|CaJ7.0416|CaO19.13990|CaJ7_0416|CaO19_6698|CaO19.6698|IPF2598 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 811390 812654 + orf19.6699 811390 812654 1 811390 812654 811518 812474 orf19.13991|IPF20484.1|IPF2596.1|Contig4-3088_0033|orf6.6808|CA4300|CaJ7.0418|CaO19.13991|HIS2|CaO19_6699|CaJ7_0418|CaO19.6699 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 812070 812761 - ntar_1142 812070 812761 1 812761 812070 812732 812502 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 812869 815073 - orf19.6701 812869 815073 1 815073 812869 815015 812940 orf19.13993|IPF20474.1|IPF2593.2|Contig4-3088_0036|orf6.6810|CA4301|CaJ7.0419|CaO19.6701|CaO19.13993|CaO19_6701|CaJ7_0419|IPF2593 Predicted ORF in Assemblies 19, 20 and 21; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 815411 817198 + orf19.6702 815411 817198 1 815411 817198 815457 817115 DED81 orf19.13994|IPF20478.1|IPF2591.1|Contig4-3088_0039|orf6.6811|CA4302|CaJ7.0421|CaO19.6702|CaO19.13994|CaJ7_0421|CaO19_6702 Putative tRNA-Asn synthetase; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 817541 819442 + orf19.6703 817541 819442 1 817541 819442 817601 819442 orf19.13995|IPF6648.2|IPF20477.1|IPF2590.2|Contig4-2958_0007|Contig4-3068_0003|Contig4-3068_0004|Contig4-3088_0040|orf6.6812|CA2451|CA4303|CaJ7.0422|orf19.5509|CaJ7_0422|CaO19_6703|CaO19.6703|LPF43|CaO19.13995|IFB1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chr7 820514 821828 + orf19.5508 820514 821828 1 820514 821828 820514 821224 IPF2589.1|Contig4-3088_0044|orf6.4356|CA2450|CaJ7.0423|CaO19.5508|LPF37|CaJ7_0423|CaO19_5508|IPF2589 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chr7 822480 824119 - orf19.5507 822480 824119 1 824119 822480 824034 822607 ENP1 IPF2587.2|Contig4-3088_0045|orf6.4355|CA2449|CaJ7.0424|CaO19.5507|CaJ7_0424|CaO19_5507 Protein similar to S. cerevisiae Enp1p; transposon mutation affects filamentous growth; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 824324 827744 - orf19.5506 824324 827744 1 827744 824324 827626 824324 PLC1 IPF2586.2|orf6.4354|CA2448|CaJ7.0425|CaJ7_0425|CaO19_5506|CaO19.5506 Phosphoinositide-specific phospholipase C (PI-PLC), delta-form; essential; roles in stress resistance, hyphal growth; upregulated in biofilm; predicted N-linked glycosylation; lacks conserved EF-hand domain [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chr7 827887 830013 - orf19.5505 827887 830013 1 830013 827887 829907 828024 HIS7 IPF2583.2|Contig4-2718_0002|Contig4-2718_0003|orf6.4353|CA2447|CaJ7.0427|CaO19.5505|CaO19_5505|CaJ7_0427 Putative imidazole glycerol phosphate synthase; histidine biosynthesis; no human/murine homolog; transcription induced by histidine starvation; regulated by Gcn2p and Gcn4p; detected by mass spec in exponential/stationary phase culture [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 830004 830494 + ntar_1143 830004 830494 1 830004 830494 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 830212 833295 - orf19.5504 830212 833295 1 833295 830212 833152 830285 IPF2582.2|Contig4-2718_0005|orf6.4352|CA2446|CaJ7.0428|CaO19.5504|CaO19_5504|CaJ7_0428|IPF2582 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr7 830976 831304 + ntar_1144 830976 831304 1 830976 831304 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 835020 835349 - orf19.5503 835020 835349 1 835349 835020 835349 835020 IPF13885.1|Contig4-2718_0008|orf6.4351|CA2445|CaJ7.0429|CaO19.5503|CaO19_5503|CaJ7_0429|IPF13885 [NOT TRANSCRIBED?] Putative protein of unknown function, transcription is upregulated in clinical isolates from HIV+ patients with oral candidiasis; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 836209 837031 + orf19.5502 836209 837031 1 836209 837031 836280 837017 IPF13883.1|Contig4-2718_0010|orf6.4350|CA2444|CaJ7.0431|CaO19_5502|CaJ7_0431|CaO19.5502|IPF13883 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr7 836323 837880 - orf19.5501 836323 837880 1 837880 836323 837811 837047 YAF9 IPF13882.1|Contig4-2718_0011|orf6.4349|CA2443|CaJ7.0432|CaJ7_0432|CaO19_5501|CaO19.5501 Subunit of the NuA4 histone acetyltransferase complex; transcription is regulated by Mig1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 838099 839678 - orf19.7204 838099 839678 1 839678 838099 839595 838234 IPF2130.2|Contig4-3097_0059|orf6.8104|CA5330|CaJ7.0433|CaJ7_0433|CaO19_7204|NPD1|CaO19.7204|IPF2130 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 840015 840720 + ntar_1420 840015 840720 2 840015|840229 840114|840720 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 840829 842149 + orf19.7203 840829 842149 1 840829 842149 840872 842041 IPF2131.2|Contig4-3097_0058|orf6.8103|CA5329|CaJ7.0434|CaO19_7203|CaJ7_0434|MRP7|CaO19.7203 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 842222 843247 + orf19.7202 842222 843247 1 842222 843247 842364 842978 IPF2132.2|Contig4-3097_0056|Contig4-3097_0057|orf6.8102|CA5328|CaJ7.0435|CaO19_7202|CaJ7_0435|RER1|CaO19.7202 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 843430 846899 + orf19.7201 843430 846899 1 843430 846899 843541 846732 SLA2 IPF2136.1|Contig4-3097_0055|orf6.8101|CA5327|CaJ7.0436|CaJ7_0436|CaO19_7201|CaO19.7201 Actin binding protein, ortholog of S. cerevisiae Sla2p; required for alkaline pH-induced hyphal formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 846620 847408 - orf19.7200 846620 847408 1 847408 846620 847360 846836 IPF2137.1|Contig4-3097_0053|orf6.8100|CA5326|CaJ7.0437|CaO19.7200|CaO19_7200|CaJ7_0437|IPF2137 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 847571 848196 - orf19.7199 847571 848196 1 848196 847571 848137 847631 IPF2138.1|Contig4-3097_0052|orf6.8099|CA5325|CaJ7.0438|CaJ7_0438|CaO19_7199|CaO19.7199|IPF2138 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 847582 847830 + ntar_1145 847582 847830 1 847582 847830 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 848221 849891 + orf19.7198 848221 849891 1 848221 849891 848780 849775 IPF2140.1|Contig4-3097_0049|orf6.8098|CA5324|CaJ7.0439|CaO19.7198|CAF40|CaO19_7198|CaJ7_0439|IPF2140 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 849951 852592 + orf19.7197 849951 852592 1 849951 852592 850094 852331 IPF2142.1|Contig4-3097_0048|orf6.8097|CA5323|CaJ7.0440|CaO19_7197|CaJ7_0440|CaO19.7197|IPF2142 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 852981 854767 + orf19.7196 852981 854767 1 852981 854767 853153 854634 PRB1|IPF2144.1|Contig4-3097_0044|Contig4-3097_0045|orf6.8096|CA5322|CaJ7.0441|CaO19.7196|PRB12|CaO19_7196|CaJ7_0441 Protein described as a vacuolar protease; upregulated in the presence of human neutrophils [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 854402 854805 - ntar_1146 854402 854805 1 854805 854402 854587 854402 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 854988 856101 + orf19.7195 854988 856101 3 854988|855314|855485 855204|855378|856101 855163 855917 RAD6 IPF2145.1|Contig4-3097_0043|orf6.8095|CA5321|CaJ7.0442|RAD6.3f|RAD6.3 Negative regulator of hyphal growth; required for wild-type UV resistance; acts in pathway with Efg1p ; functional homolog of S. cerevisiae Rad6p; transcription is UV-induced, slightly repressed during hyphal growth; gene has two introns [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 855891 856999 - orf19.7194 855891 856999 1 856999 855891 856999 856073 IPF2147|IPF2147.2|Contig4-3097_0041|orf6.8094|CA5320|CaJ7.0443|CaO19_7194|CaJ7_0443|CaO19.7194 Protein not essential for viability; decreased transcription is observed upon fluphenazine treatment; induced upon adherence to polystyrene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr7 857069 859301 - orf19.7193 857069 859301 1 859301 857069 859180 857150 IPF2150.2|Contig4-3097_0040|orf6.8093|CA5319|CaJ7.0445|SSH4|CaO19.7193|CaJ7_0445|CaO19_7193|IPF2150 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 859734 860063 + orf19.7192 859734 860063 1 859734 860063 859734 860063 IPF27370.1|orf6.8092|CaJ7.0446|CaJ7_0446|CaO19_7192|CaO19.7192 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 860076 861390 + orf19.7190 860076 861390 1 860076 861390 860197 861258 OGG1 IPF2154.1|Contig4-3097_0039|orf6.8090|CA5318|CaJ7.0448|CaO19.7190|CaJ7_0448|CaO19_7190 Ortholog of S. cerevisiae OGG1, which encodes a mitochondrial DNA glycosylase/lyase involved in base excision repair; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 861238 861791 - orf19.7188 861238 861791 1 861791 861238 861769 861443 RPP1B RP1B|CARP1B|IPF2156.1|RPP1A-2|Contig4-3097_0037|orf6.8088|CA5317|CaJ7.0449|CaJ7_0449|CaO19_7188|CaO19.7188 Conserved acidic ribosomal protein, likely to be involved in regulation of translation elongation; interacts with Rpp2Ap; one of four similar C. albicans ribosomal proteins (Rpp1Ap, Rpp1Bp, Rpp2Ap, Rpp2Bp); transcription activated by Tbf1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 861959 862978 - orf19.7187 861959 862978 1 862978 861959 862917 862123 MAM33 IPF2157.1|Contig4-3097_0036|orf6.8087|CA5316|CaJ7.0451|CaO19_7187|CaJ7_0451|CaO19.7187 Predicted ORF in Assemblies 19, 20 and 21; regulated by Ssn6p; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 863046 865562 - orf19.7186 863046 865562 1 865562 863046 864801 863341 CLB4 orf6.8086|CYB4|CYB99|CYB2|IPF2159.2|Contig4-3097_0035|CA5315|CaJ7.0452|CaO19.7186|CaJ7_0452|CaO19_7186 B-type mitotic cyclin; nonessential; negative regulator of pseudohyphal growth; dispensible for mitotic exit, cytokinesis; increased CLB4 transcript detected in fkh2 mutant; farnesol-upregulated in biofilm; reduced total RNA in clb4 mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 865906 866021 - tl(uaa)5 865906 866021 2 866021|865951 865983|865906 tRNA-Leu predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 866333 867936 - orf19.7185 866333 867936 1 867936 866333 867936 866479 IPF2161.2|Contig4-3097_0033|orf6.8085|CA5314|CaJ7.0453|CaJ7_0453|CaO19_7185|HAT2|CaO19.7185 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 868083 868775 - orf19.7184 868083 868775 1 868775 868083 868566 868102 IPF2163.2|Contig4-3097_0032|orf6.8084|CA5313|CaJ7.0454|CaO19_7184|CaJ7_0454|CaO19.7184|VPS552|IPF2163 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 868733 869625 + orf19.7183 868733 869625 1 868733 869625 868860 869390 IPF2165.1|Contig4-3097_0030|orf6.8083|CA5312|CaJ7.0455|CaO19.7183|CaO19_7183|CaJ7_0455|IPF2165 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 869275 870306 - orf19.7182 869275 870306 1 870306 869275 870254 869448 IPF2166.1|Contig4-3097_0028|orf6.8082|CA5311|CaJ7.0456|CaO19_7182|CaJ7_0456|CaO19.7182|IPF2166 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 870406 872191 + orf19.7181 870406 872191 1 870406 872191 870489 872147 IPF2167.1|Contig4-3097_0026|orf6.8081|CA5310|CaJ7.0457|CaO19.7181|CaJ7_0457|CaO19_7181|IPF2167 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 872303 874277 + orf19.7179 872303 874277 1 872303 874277 872321 874237 IPF2170.1|Contig4-3097_0025|orf6.8079|CA5309|CaJ7.0459|SSC1|CaO19.7179|CaJ7_0459|CaO19_7179|IPF2170 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 874143 875264 - orf19.7178 874143 875264 1 875264 874143 875213 874362 PRE5 IPF2171.1|Contig4-3097_0023|orf6.8078|CA5308|CaJ7.0460|CaO19.7178|CaJ7_0460|CaO19_7178 Alpha6 subunit of the 20S proteasome; regulated by Gcn4p; induced in response to amino acid starvation (3-aminotriazole treatment) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 875377 878419 - orf19.7177 875377 878419 1 878419 875377 878376 875434 KAP120 IPF2172.1|Contig4-3097_0022|orf6.8077|CA5307|CaJ7.0461|CaO19.7177|CaO19_7177|CaJ7_0461|IPF2172 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to cytochalasin D [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 878433 880157 - orf19.7176 878433 880157 1 880157 878433 879887 878622 NPT1 IPF2173.1|Contig4-3097_0021|orf6.8076|CA5306|CaJ7.0462|CaO19.7176|CaO19_7176|CaJ7_0462 Putative nicotinate phosphoribosyltransferase, involved in NAD salvage pathway; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 880246 881541 + orf19.7175 880246 881541 1 880246 881541 880388 881383 HLJ1 IPF2175.1|Contig4-3097_0019|orf6.8075|CA5305|CaJ7.0464|CaJ7_0464|CaO19_7175|CaO19.7175|IPF2175 Protein repressed during the mating process [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 881544 883338 + orf19.7173 881544 883338 1 881544 883338 881593 883314 IPF2178.1|Contig4-3097_0018|orf6.8073|CA5304|CaJ7.0466|CaJ7_0466|CaO19_7173|CaO19.7173|IPF2178 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 883500 883889 - orf19.7170 883500 883889 1 883889 883500 883889 883500 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 885221 886021 - orf19.7167 885221 886021 1 886021 885221 886021 885221 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 887185 888683 - orf19.7166 887185 888683 1 888683 887185 888621 887278 IPF2186.1|Contig4-3097_0006|orf6.8066|CA5301|CaJ7.0473|CaO19_7166|CaJ7_0473|CaO19.7166|IPF2186 Predicted ORF in Assemblies 19, 20 and 21; increased transcription is observed in an azole-resistant strain that overexpresses MDR1; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 888976 889124 - ntar_1147 888976 889124 1 889124 888976 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 889260 890240 - orf19.7165 889260 890240 1 890240 889260 890240 889584 IPF2189.1|Contig4-3097_0004|orf6.8065|CA5300|CaJ7.0474|CaO19.7165|CaJ7_0474|CaO19_7165|IPF2189 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chr7 890266 891542 + orf19.7164 890266 891542 1 890266 891542 890363 891457 IPF2190.1|Contig4-3097_0002|orf6.8064|CA5299|CaJ7.0475|CaJ7_0475|CaO19_7164|CaO19.7164|IPF2190 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 891596 892194 + orf19.7163 891596 892194 1 891596 892194 891606 892013 IPF2191.2|Contig4-3097_0001|orf6.8063|CaO19.7163 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 892015 893026 - orf19.7161 892015 893026 1 893026 892015 892977 892132 SUI3 IPF19809.1|Contig4-3097_0060|orf6.8061|CA5298|CaJ7.0477|CaJ7_0477|CaO19_7161|CaO19.7161 Putative translation initiation factor; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 893091 893876 - orf19.7160 893091 893876 1 893876 893091 893852 893214 IPF1957.1|orf6.8060|CA5297|CaJ7.0479|CaO19.7160|YAR1|CaJ7_0479|CaO19_7160 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 893961 897103 + orf19.7159 893961 897103 1 893961 897103 894002 896905 IPF1956.1|Contig4-3083_0030|orf6.8059|CA5296|CaJ7.0480|CaJ7_0480|CaO19_7159|CaO19.7159|IPF1956 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chr7 897177 898838 + orf19.7158 897177 898838 1 897177 898838 897177 898838 IPF1954.1|Contig4-3083_0001|orf6.8058|CA5295|CaJ7.0481|CaO19_7158|CaJ7_0481|CaO19.7158|IPF1954 Protein of allantoate permease family; fungal-specific (no human or murine homolog) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chr7 897262 897580 - ntar_1148 897262 897580 1 897580 897262 897387 897262 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 897914 898138 - ntar_1149 897914 898138 1 898138 897914 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 898344 898635 - ntar_1150 898344 898635 1 898635 898344 898635 898414 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 898932 899818 + orf19.7157 898932 899818 2 898932|899009 898956|899818 898941 899760 IPF1952.1|Contig4-3083_0002|orf6.8057|CA5294|CaJ7.0482|CaO19.7157|CaO19_7157|CaJ7_0482|IPF1952 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 900106 902348 + orf19.7156 900106 902348 1 900106 902348 900108 902348 FAA2-3 IPF1949.1|Contig4-3083_0004|orf6.8056|CA5293|CaJ7.0483|FAA23|CaJ7_0483|CaO19_7156|CaO19.7156|FAA24 Predicted acyl CoA synthetase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 902285 904072 - orf19.7154 902285 904072 1 904072 902285 904056 902398 UTP18 IPF1948.1|Contig4-3083_0005|orf6.8054|CA5292|CaJ7.0484|CaO19.7154|CaJ7_0484|CaO19_7154|IPF1948 Predicted ORF in Assemblies 19, 20 and 21; downregulated during core stress response; physically interacts with TAP-tagged Nop1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 904180 907451 - orf19.7153 904180 907451 1 907451 904180 907312 904235 IPF1945.2|Contig4-3083_0006|orf6.8053|CA5291|CaJ7.0486|CaO19_7153|CaJ7_0486|LOS1|CaO19.7153 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 907563 908888 - orf19.7152 907563 908888 1 908888 907563 908685 907588 IPF1943.2|Contig4-3083_0008|Contig4-3083_0009|orf6.8052|CA5290|CaJ7.0487|CYS4|CaO19.7152|CaJ7_0487|CaO19_7152|IPF1943 Protein similar to Aspergillus CYSK O-acetylserine sulfhydrylase, suggesting that C. albicans uses an O-acetyl-serine (OAS) pathway of sulfur assimilation; upregulated in biofilm; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 912160 912795 - ntar_1151 912160 912795 1 912795 912160 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 915019 915161 - ntar_1152 915019 915161 1 915161 915019 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 915482 915780 - ntar_1153 915482 915780 1 915780 915482 915780 915574 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 915533 915967 + orf19.7151 915533 915967 1 915533 915967 915533 915967 IPF1935.2|Contig4-3083_0015|orf6.8051|CaJ7.0488|CaO19.7151|CaJ7_0488|CaO19_7151 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 918382 919948 + orf19.7150 918382 919948 1 918382 919948 918848 919780 NRG1 IPF1932.1|Contig4-3083_0019|orf6.8050|CA5289|CaJ7.0489|CaO19_7150|CaJ7_0489|CaO19.7150 Transcriptional repressor; regulates hyphal genes, virulence genes, chlamydospore development, and genes involved in rescue and stress responses; effects both Tup1p-dependent (major) and -independent (minor) regulation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 924375 926417 - orf19.7149 924375 926417 1 926417 924375 926413 924665 IPF1928.2|Contig4-2346_0001|Contig4-2346_0002|orf6.8049|CA5288|CaJ7.0490|CaO19.7149|CaJ7_0490|CaO19_7149|IPF1928 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 928161 928395 + ntar_1154 928161 928395 1 928161 928395 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 928833 930524 + orf19.7148 928833 930524 1 928833 930524 928833 930524 TPO2 IPF1922.2|Contig4-2346_0003|orf6.8048|TPO1|CA5287|CaJ7.0493|CaJ7_0493|CaO19_7148|CaO19.7148|IPF1922 Putative polyamine transport protein; fungal-specific (no human or murine homolog) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 929852 930568 - ntar_1155 929852 930568 1 930568 929852 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chr7 930572 932861 + orf19.7144 930572 932861 2 930572|931238 930817|932861 930583 932715 IPF1919.2|orf6.8044|CA5285|CaJ7.0498|HBS1|HBS1.3f|IPF1918.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 932681 933627 - orf19.7141 932681 933627 1 933627 932681 933627 932707 UFE1 orf6.8041|IPF1914.1|Contig4-2757_0012|CA5284|CaJ7.0500|CaJ7_0500|CaO19_7141|CaO19.7141 Protein interacting with Sec20p, possibly involved in retrograde transport between the Golgi and the endoplasmic reticulum; functional homolog of S. cerevisiae Ufe1p, which is an ER t-SNARE that mediates the retrograde traffic [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 933680 934437 - orf19.7140 933680 934437 1 934437 933680 934426 933680 IPF1912.1|Contig4-2757_0011|orf6.8040|CA5283|CaJ7.0501|CaO19_7140|CaJ7_0501|CMT1|CaO19.7140|IPF1912 Putative protein of unknown function, transcription is upregulated in clinical isolates from HIV+ patients with oral candidiasis; predicted ORF in Assemblies 19, 20 and 21; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 934496 934894 + orf19.7139 934496 934894 1 934496 934894 934496 934894 IPF1911.1|Contig4-2757_0009|orf6.8039|CA5282|CaJ7.0502|CaJ7_0502|CaO19_7139|CaO19.7139|IPF1911 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 934914 939301 + orf19.7136 934914 939301 1 934914 939301 934914 939119 SPT6 IPF1910.1|Contig4-2757_0008|orf6.8036|CA5281|CaJ7.0509|CaO19.7136|CaJ7_0509|CaO19_7136 Protein similar to S. cerevisiae Spt6p transcription elongation factor; transposon mutation affects filamentous growth; transcription is upregulated in an RHE model of oral candidiasis and in clinical isolates from oral candidiasis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chr7 939057 940449 - orf19.7131 939057 940449 1 940449 939057 940339 939116 IPF1899.2|Contig4-2757_0007|orf6.8031|CA5280|CaJ7.0511|CaO19.7131|BBH1|CaJ7_0511|IPF1899 Butyrobetaine dioxygenase, the fourth enzyme of the carnitine biosynthesis pathway [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 940347 940976 + orf19.7130 940347 940976 1 940347 940976 940494 940895 IPF1896.2|Contig4-2757_0004|orf6.8030|CaJ7.0512|CaO19.7130|CaO19_7130|CaJ7_0512 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 940750 941567 - orf19.7128 940750 941567 1 941567 940750 941535 941029 SYS1 IPF1895.1|orf6.8028|CA5279|CaJ7.0514|CaO19.7128|CaJ7_0514|CaO19_7128 Predicted ORF in Assemblies 19, 20 and 21; transcription is regulated by Mig1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chr7 942055 942471 - orf19.7127.1 942055 942471 1 942471 942055 942255 942055 IPF1893.1|CA5278|CTA29.3f|CTA29.exon2 Putative protein of unknown function, transcription is upregulated in an RHE model of oral candidiasis; ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chr7 942861 943388 - orf19.7127 942861 943388 1 943388 942861 943388 942861 TLO16 IPF1892.1|Contig4-2584_0003|Contig4-3013_0007|orf6.8027|CA5277|CaJ7.0516|TLO16b|CaO19_7127|CaJ7_0516|CaO19.7127|CTA227|CTA29.5f|CTA29.exon1 Member of a family of telomere-proximal genes of unknown function; may be spliced in vivo [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chr7 944915 945041 - ntar_1156 944915 945041 1 945041 944915 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 4637 6890 - orf19.7545 4637 6890 1 6890 4637 6890 4884 IPF324.2|Contig4-2956_0011|orf6.8797|CA5875|CaO19.7545|IPF324.3f|IPF324.3 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chrR 5057 7614 + ntar_1157 5057 7614 1 5057 7614 6975 7214 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 7530 8580 - ntar_1421 7530 8580 3 8580|8350|8196 8405|8252|7530 8557 8314 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chrR 9111 9863 + orf19.7544 9111 9863 1 9111 9863 9111 9863 TLO1 CTA2|IPF328.2|Contig4-2956_0006|orf6.8796|CA5874|CaO19.7544|CTA216|CTA23 Member of a family of telomere-proximal genes of unknown function; hyphal-induced expression [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 10308 10418 + tl(caa)6 10308 10418 2 10308|10375 10346|10418 tRNA-Leu predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 10646 12120 - orf19.7539.1 10646 12120 1 12120 10646 11815 10646 CaO19.7542 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chrR 13669 14871 + orf19.7539 13669 14871 1 13669 14871 13684 14823 INO2 IPF333.1|Contig4-3048_0008|orf6.8791|CA5872|CaO19.7539|IPF333 Transcriptional activator that may be involved in regulation of ribosomal protein genes; forms a heterodimer with Ino4p; related to S. cerevisiae Ino2p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 14826 16827 - orf19.7538 14826 16827 1 16827 14826 16827 14971 IPF336.1|Contig4-3048_0007|orf6.8790|CA5871|PIF1|CaO19.7538|PIF2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chrR 16909 21366 + orf19.7537 16909 21366 1 16909 21366 16909 21366 BNR1 IPF345.1|Contig4-3048_0005|orf6.8789|CA5870|BNI1|CaO19.7537|IPF345 Formin; probable role in hyphal cytoskeletal polarity; synthetic lethality if Bnr1p and Bni1p are absent [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 21385 24518 + orf19.7534 21385 24518 1 21385 24518 21385 24462 MIS12 IPF349.1|Contig4-3048_0003|Contig4-3048_0004|CA5869|CaO19.7534|MIS1|orf6.8786 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 24438 25163 - orf19.7531 24438 25163 1 25163 24438 25163 24474 IPF351.1|IPF351|Contig4-3048_0002|orf6.8783|YMR90|CA5868|CaO19.7531 Predicted ORF in Assemblies 19, 20 and 21; transcription is induced upon yeast-hyphal transition; benomyl or caspofungin induced; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 25226 28369 - orf19.7529 25226 28369 1 28369 25226 27540 25279 EPL1 IPF355.1|Contig4-3048_0022|orf6.8781|CA5867|CaO19.7529 Subunit of the NuA4 histone acetyltransferase complex [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 28506 30784 + orf19.7527 28506 30784 1 28506 30784 28507 30687 IPF361.1|Contig4-2252_0004|orf6.8779|CA5866|CaO19.7527|IPF361 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 30695 32448 - orf19.7523 30695 32448 1 32448 30695 32402 30873 MKC1 IPF363.1|Contig4-2252_0001|orf6.8775|CA5865|CaO19.7523 MAP kinase; role in biofilm formation, contact-induced invasive filamentation, systemic virulence in mouse, cell wall structure/maintenance, caspofungin response; phosphorylated on surface contact, membrane perturbation, or cell wall stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 32969 34269 - orf19.7522 32969 34269 1 34269 32969 34247 33075 IPF364.2|Contig4-2252_0002|orf6.8774|CA5864|CaO19.7522|IPF364 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to amphotericin B [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 36338 38985 + orf19.7521 36338 38985 1 36338 38985 36752 38833 REP1 IPF370.2|Contig4-3107_0081|orf6.8773|CA5863|CaO19.7521|IPF370 Protein involved in negative regulation of MDR1 transcription; mutants show increased resistance to azole drugs [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 38892 40359 - orf19.7520 38892 40359 1 40359 38892 40227 39001 POT1 IPF372.1|POT11|Contig4-3107_0080|orf6.8772|CA5862|CaO19.7520 Putative peroxisomal 3-oxoacyl CoA thiolase; transcription is regulated by Nrg1p and Mig1p; farnesol regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 40753 41742 - orf19.7519 40753 41742 1 41742 40753 41283 40843 IPF373.1|Contig4-3107_0078|orf6.8771|CA5861|CaO19.7519|IPF373 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 41616 43456 + orf19.7518 41616 43456 1 41616 43456 41616 43364 ZCF38|IPF376.1|Contig4-3107_0075|orf6.8770|CA5860|TEA2|CaO19.7518|IPF376 Putative transcription factor with zinc cluster DNA-binding motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chrR 43250 44903 - orf19.7517 43250 44903 1 44903 43250 44739 43351 CHT1 IPF377.2|Contig4-3107_0074|orf6.8769|CA5859|CaO19.7517 Chitinase; putative N-terminal catalytic domain; has secretory signal sequence; lacks S/T region and N-glycosylation motifs of Chs2p and Chs3p; alkaline downregulated; expression not detected in yeast-form or hyphal cells [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 45534 48498 + orf19.7516 45534 48498 1 45534 48498 45583 48474 IPF380.1|Contig4-3107_0072|orf6.8768|CA5858|BGL97|CaO19.7516|IPF380 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 49543 51401 + orf19.7514 49543 51401 1 49543 51401 49655 51316 PCK1 IPF385.1|Contig4-3107_0068|orf6.8766|CA5857|CaO19.7514 Phosphoenolpyruvate carboxykinase; role in gluconeogenesis; regulated by hyphal switch, carbon source; repressed on glucose; induced by fluconazole, phagocytosis, H2O2; predicted ATP-dependent, dimeric; predicted PKC phosphorylation sites [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 52216 53972 + orf19.7513 52216 53972 1 52216 53972 52344 53912 IPF387.1|Contig4-3107_0066|orf6.8765|CA5856|ALK2|CaO19.7513 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 54267 56480 + orf19.7512 54267 56480 1 54267 56480 54836 56452 IPF389.2|Contig4-3107_0063|Contig4-3107_0064|orf6.8764|CA5855|CaO19.7512|ALK3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 54400 54545 - ntar_1158 54400 54545 1 54545 54400 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 56598 62206 + orf19.7511 56598 62206 1 56598 62206 56627 62170 IPF393.2|Contig4-3107_0058|Contig4-3107_0062|orf6.8763|CA5854|NUP192|CaO19.7511|IPF393 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 62271 62611 + orf19.7509.2 62271 62611 2 62271|62550 62490|62611 62271 62572 LSM6 IPF395.1|Contig4-3107_0056|CA5853 ORF Predicted by Annotation Working Group; flucytosine induced [label_first_exon=CGD label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 62766 63219 + orf19.7509.1 62766 63219 2 62766|62919 62856|63219 62794 63164 ATP17 IPF396.1|Contig4-3107_0055|CA5852|ATP17.3 Protein described as a component of mitochondrial ATPase complex; downregulated by Efg1p; flucytosine induced; caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 63479 67427 + orf19.7510 63479 67427 1 63479 67427 63737 67375 KIN2 IPF402.1|Contig4-3107_0054|orf6.8762|CA5851|CaO19.7510|KIN1 Putative protein of with similarity to S. cerevisiae Kin2p, transcription is positively regulated by Tbf1; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 67328 67866 - orf19.7507 67328 67866 1 67866 67328 67866 67399 IPF403.1|Contig4-3107_0053|orf6.8759|CA5850|CaO19.7507|IPF404.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 67793 69027 - orf19.7506 67793 69027 1 69027 67793 69016 67793 IPF404.1|Contig4-3107_0051|orf6.8758|CA5849|CaO19.7506|IPF404.5f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 71974 73232 + orf19.7504 71974 73232 1 71974 73232 72120 73049 IPF407.1|Contig4-3107_0046|orf6.8756|CA5848|CaO19.7504|IPF407 Predicted ORF in Assemblies 19, 20 and 21; Plc1p-regulated; induced in core caspofungin response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 73423 74526 + orf19.7503 73423 74526 1 73423 74526 73423 74526 CDA2 IPF408.1|Contig4-3107_0044|orf6.8755|CA5847|CaO19.7503 Putative protein of unknown function, transcription is positively regulated by Tbf1p; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 75418 77003 - orf19.7502 75418 77003 1 77003 75418 76707 75931 IPF409.1|Contig4-3107_0039|orf6.8754|CA5846|RNT1|CaO19.7502|IPF409 Predicted ORF in Assemblies 19, 20 and 21; greater mRNA abundance observed in a cyr1 homozygous null mutant than in wild type; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 81968 83545 - orf19.7501 81968 83545 1 83545 81968 83460 82153 IPF412.1|Contig4-3107_0030|orf6.8753|CA5845|CaO19.7501|NAP1 Predicted ORF in Assemblies 19, 20 and 21; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 83755 86323 - orf19.7500 83755 86323 1 86323 83755 86206 83900 PXA1 IPF414.1|Contig4-3107_0029|orf6.8752|CA5844|CaO19.7500 Putative peroxisomal, half-size adrenoleukodystrophy protein (ALD or ALDp) subfamily ABC family transporter [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 86624 87225 - orf19.7499.1 86624 87225 1 87225 86624 87087 86896 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 87815 89426 + orf19.7499 87815 89426 1 87815 89426 88067 89272 IPF416.1|Contig4-3107_0023|orf6.8751|CA5843|CaO19.7499|IPF416 Putative nicotinic acid mononucleotide adenylyltransferase, involved in NAD salvage pathway [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 89359 91854 - orf19.7498 89359 91854 1 91854 89359 91784 89454 LEU1 IPF417.2|Contig4-3107_0022|orf6.8750|CA5842|CaO19.7498 Protein described as 3-isopropylmalate dehydratase; antigenic in human; decreased expression in hyphae compared to yeast-form cells; alkaline downregulated; upregulated in the presence of human whole blood or polymorphonuclear (PMN) cells [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 92267 95016 + orf19.7497 92267 95016 1 92267 95016 92319 94898 IPF420.2|Contig4-3107_0021|orf6.8749|CA5841|CaO19.7497|IPF420 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 95173 96656 + orf19.7495 95173 96656 1 95173 96656 95291 96589 IPF421.1|Contig4-3107_0020|orf6.8747|CA5840|CaO19.7495|OYE30|EBP6 Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chrR 96961 102153 + orf19.7494 96961 102153 1 96961 102153 96961 102075 IPF423.1|Contig4-3107_0017|orf6.8746|CA5839|CaO19.7494|IPF423 Predicted ORF in Assemblies 19, 20 and 21; cell-cycle regulated periodic mRNA expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chrR 101932 104087 - orf19.7492 101932 104087 1 104087 101932 104010 102103 SWC4 IPF424.1|Contig4-3107_0014|orf6.8744|CA5838|CaO19.7492|IPF424 Subunit of the NuA4 histone acetyltransferase complex [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 104187 105468 + orf19.7491 104187 105468 1 104187 105468 104234 105313 IPF426.1|Contig4-3107_0013|orf6.8743|CA5837|RTT109|CaO19.7491|IPF426 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 105677 107474 + orf19.7490 105677 107474 1 105677 107474 105871 107460 IPF428.1|Contig4-3107_0012|orf6.8742|CA5836|CaO19.7490|IPF428 Predicted membrane transporter, member of the fucose:proton symporter (FHS) family, major facilitator superfamily (MFS) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 107328 107929 - orf19.7489.3 107328 107929 1 107929 107328 107864 107595 IPF429.1|Contig4-3107_0011|CA5835|IPF429 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 108039 113825 - orf19.7489 108039 113825 1 113825 108039 112632 108226 IPF434.1|Contig4-3107_0010|orf6.8741|CA5834|CaO19.7489|LRG1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 115400 116244 - orf19.7488 115400 116244 1 116244 115400 116160 115609 IPF436.1|Contig4-3107_0006|orf6.8740|CA5833|CaO19.7488|IMP3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 116405 117053 - ntar_1159 116405 117053 1 117053 116405 116664 116503 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 116823 118079 + orf19.7487 116823 118079 1 116823 118079 116823 118079 IPF437.1|Contig4-3107_0004|orf6.8739|CA5832|POL91|CaO19.7487|Zorro1c Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 117317 117648 - ntar_1160 117317 117648 1 117648 117317 117568 117392 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 117798 118187 - ntar_1161 117798 118187 1 118187 117798 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 118366 119182 + orf19.7486 118366 119182 1 118366 119182 118396 119097 MRPL6 IPF438.2|Contig4-3107_0001|orf6.8738|CA5831|CaO19.7486 Putative mitochondrial ribosomal protein [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 119339 120321 + orf19.7485 119339 120321 1 119339 120321 119377 120258 IPF2480.2|Contig4-2988_0018|orf6.8737|CA5830|MRPL9|CaO19.7485 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 120285 120551 - ntar_1162 120285 120551 1 120551 120285 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 120706 120840 - snrnau5 120706 120840 1 120840 120706 Highly conserved U5 small nuclear RNA involved in splicing; exists predominantly as a short form lacking the 3' 18 nt of the annotated sequence, but full-length transcript is also present in vivo; ortholog of S. cerevisiae SNR7-L and SNR7-S [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 120897 121888 - orf19.7484 120897 121888 1 121888 120897 121861 120986 ADE1 IPF2482.1|Contig4-2988_0016|orf6.8736|CA5829|CaO19.7484 Phosphoribosylaminoimadazole succinocarboxamide synthetase, enzyme of adenine biosynthesis; not induced during GCN response, in contrast to the S. cerevisiae ortholog; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 122042 125956 - orf19.7483 122042 125956 1 125956 122042 125565 122326 CRM1 IPF2484.2|Contig4-2988_0014|Contig4-2988_0015|orf6.8735|CA5828|CaO19.7483 Functional homolog of S. cerevisiae Crm1p, which acts in protein nuclear export; predicted to be resistant to antifungal drug leptomycin B; partially suppresses signal transduction defects of S. cerevisiae ste20 mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 125674 125922 + ntar_1163 125674 125922 1 125674 125922 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 126534 127088 + orf19.7482 126534 127088 1 126534 127088 126534 127088 IPF2485.1|Contig4-2988_0013|orf6.8734|CA5827|CaO19.7482|IPF2485 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 127073 128351 - orf19.7481 127073 128351 1 128351 127073 128189 127176 MDH1 orf6.8733|IPF2486.1|MDH1-2|Contig4-2988_0011|CA5826|CaO19.7481|MDH2|MDH11 Protein described as malate dehydrogenase, mitochondrial; transcription regulated by Mig1p and Tup1p, white-opaque switching; induced in high iron, biofilm; regulated upon phagocytosis; antigenic during murine or human infection [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 129416 130015 + orf19.7480 129416 130015 1 129416 130015 129416 130015 IPF2489.1|Contig4-2988_0009|orf6.8732|CA5825|CaO19.7480|IPF2489 Putative protein of unknown function, transcription is upregulated in clinical isolates from HIV+ patients with oral candidiasis; predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 129952 130145 - ntar_1164 129952 130145 1 130145 129952 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 130500 133424 + orf19.7479 130500 133424 1 130500 133424 130650 133373 NTH1 orf6.8731|NTC1|IPF2490.1|Contig4-2988_0007|CA5824|CaO19.7479 Neutral trehalase; hyphal induction in homozygous null mutant is delayed but not reduced overall; not required for virulence in mouse systemic infection; homodimeric enzyme; possible regulatory cAMP-dependent phosphorylation at S10 and S213 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 132856 133742 - ntar_1165 132856 133742 1 133742 132856 133032 132856 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 133873 135680 + orf19.7478 133873 135680 1 133873 135680 134047 135579 IPF2493.1|Contig4-2988_0006|orf6.8730|CA5823|COQ1|CaO19.7478 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 135935 137081 + orf19.7477 135935 137081 1 135935 137081 136157 136795 YRB1 orf6.8729|IPF2494.1|Contig4-2988_0004|CA5822|CaO19.7477 Functional homolog of S. cerevisiae Yrb1p, which regulates Gsp1p GTPase activity and thereby affects nucleocytoplasmic transport and cytoskeletal dynamics; transcription is not regulated by white-opaque switching or by dimorphic transition [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 137391 141502 + orf19.7475 137391 141502 1 137391 141502 137391 141383 PHO81 IPF2499.1|Contig4-2988_0003|orf6.8727|CA5821|CaO19.7475 Predicted ORF in Assemblies 19, 20 and 21; possibly adherence-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chrR 141352 143877 - orf19.7473 141352 143877 1 143877 141352 143784 141511 IPF2500.2|Contig4-2988_0019|orf6.8725|CA5820|CaO19.7473|IPF2500 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 145031 149611 + orf19.7472 145031 149611 1 145031 149611 145031 149611 IFF4 IPF2507.1|Contig4-3027_0015|orf6.8724|CA5819|CaO19.7472 Putative GPI-anchored protein; homozygous null mutant germ tubes show decreased adhesion to plastic substrate; not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chrR 149775 151359 - orf19.7469 149775 151359 1 151359 149775 151359 149878 ARG1 IPF2508.1|Contig4-3027_0013|orf6.8721|CA5818|CaO19.7469 Similar to argininosuccinate synthase; enzyme of arginine biosynthesis; increased transcription is observed upon benomyl treatment; regulated by Gcn4p, Rim101p; induced in response to amino acid starvation (3-aminotriazole treatment) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chrR 152025 153928 + orf19.7468 152025 153928 1 152025 153928 152187 153800 IPF2511.1|Contig4-3027_0009|Contig4-3027_0011|orf6.8720|CA5817|CaO19.7468|IPF2511 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 153346 153912 - ntar_1166 153346 153912 1 153912 153346 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 154603 162217 + orf19.7466 154603 162217 2 154603|155254 154869|162217 155339 162019 ACC1 IPF2516.1|Contig4-3027_0007|orf6.8718|CA5816|CaO19.7466 Protein with similarity to acetyl-coenzyme-A carboxylases; regulated by Efg1p; amphotericin B repressed; caspofungin repressed; intron in 5'-UTR [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chrR 163022 164161 + orf19.7464 163022 164161 1 163022 164161 163022 164161 IPF2517.1|Contig4-3027_0005|orf6.8716|CA5815|CaO19.7464|IPF2517 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to toxic ergosterol analog [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 164523 165788 + orf19.7463 164523 165788 1 164523 165788 164523 165788 IPF2521.1|Contig4-3027_0001|orf6.8715|CA5814|CaO19.7463|IPF2521 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chrR 165691 167137 - orf19.7460 165691 167137 1 167137 165691 167072 165840 IPF2522.1|Contig4-3027_0019|orf6.8712|CA5813|CaO19.7460|IPF2522 Putative protein of unknown function, transcription is activated in the presence of elevated CO2; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 167225 168690 + orf19.3287 167225 168690 1 167225 168690 167253 168632 BUD22 orf19.10797|IPF24049.1|IPF16944.2|Contig4-1655_0004|orf6.8287|CA5474|IPF16944.3eoc Predicted ORF in Assemblies 19, 20 and 21; downregulated during core stress response; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 168573 170127 - orf19.3286 168573 170127 1 170127 168573 170088 168760 orf19.10796|IPF24035.1|IPF16947.2|Contig4-1655_0001|Contig4-1655_0002|orf6.8286|CA5473|CaO19.3286|CaO19.10796|IPF16947 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 170204 171612 + orf19.3285 170204 171612 1 170204 171612 170227 171612 orf19.10795|IPF24036.1|IPF16948.2|orf6.8285|CA5472|CaO19.10795|CaO19.3285|IPF16948 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chrR 171563 172364 - orf19.3283 171563 172364 1 172364 171563 172342 171653 orf19.10793|IPF24050.1|IPF302.2|orf6.8283|CA5471|OAR1|CaO19.10793|CaO19.3283|IPF302 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 171669 171992 + orf19.3284 171669 171992 1 171669 171992 171669 171992 orf6.8284 [NOT TRANSCRIBED?] ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 172440 172512 - tt(agu)3 172440 172512 1 172512 172440 tT(AGU)3.2 tRNA-Thr predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 172783 174788 - orf19.3282 172783 174788 1 174788 172783 174635 172986 BMT3 orf19.10792|IPF24024.1|IPF300.1|Contig4-2592_0002|orf6.8282|CA5470|WRY9|CaO19.10792|CaO19.3282|IPF300 Putative beta-mannosyltransferase, required for addition of the 2nd beta-mannose to the acid-stable fraction of cell wall phosphopeptidomannan and for elongation of beta-mannose chains on the phosphopeptidomannan acid-labile fraction [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 175639 177289 - orf19.3281 175639 177289 1 177289 175639 177251 175815 orf19.10791|IPF24034.1|IPF298.1|Contig4-2592_0004|orf6.8281|CA5469|CaO19.10791|CaO19.3281|IPF298 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 176116 176418 + ntar_1167 176116 176418 1 176116 176418 176221 176418 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 177632 181495 - orf19.3279 177632 181495 1 181495 177632 181477 177800 HYR4 orf19.10789|IFF7|IPF24076.1|IPF296.1|Contig4-2791_0017|orf6.8279|CA5468|HYR8|CaO19.10789|CaO19.3279 Putative GPI-anchored protein of unknown function; transcription is negatively regulated by Rim101p; constitutive expression independent of MTL or white-opaque status [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 178157 178540 + orf19.3280 178157 178540 1 178157 178540 178157 178540 IPF24069.1|IPF28834.1|orf6.8280 [NOT TRANSCRIBED?] ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 181984 182167 + ntar_1168 181984 182167 1 181984 182167 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 182201 184364 - orf19.3278 182201 184364 1 184364 182201 184247 182262 GSY1 orf19.10788|IPF24014.1|IPF294.1|Contig4-2791_0013|orf6.8278|CA5467|CaO19.3278|CaO19.10788 Protein described as glycogen synthase; enzyme of glycogen metabolism; transcription downregulated upon yeast-hyphal switch and regulated by Efg1p; strong oxidative stress induced; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 185406 185744 - orf19.3277 185406 185744 1 185744 185406 185744 185406 orf19.10787|IPF24082.1|IPF28838.1|orf6.8277|CaO19.10787|CaO19.3277 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 186069 189070 - orf19.3276 186069 189070 1 189070 186069 189010 186242 PWP2 orf19.10786|IPF23987.1|IPF290.1|Contig4-2791_0009|orf6.8276|CA5466|CaO19.10786|CaO19.3276 Predicted ORF in Assemblies 19, 20 and 21; downregulated during core stress response; decreased expression in response to prostaglandins; physically interacts with TAP-tagged Nop1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 186236 186422 + ntar_1169 186236 186422 1 186236 186422 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 189199 189980 + orf19.3275 189199 189980 1 189199 189980 189245 189640 orf19.10785|IPF24063.1|IPF288.1|Contig4-2791_0005|orf6.8275|CaO19.3275|CaO19.10785 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 189429 190781 - orf19.3273 189429 190781 2 190781|189873 189965|189429 190663 189682 orf19.10783|orf19.10784|IPF24047.1|IPF285.1|Contig4-2791_0003|orf6.8273|orf6.8274|CA5464|CA5465|orf19.3274|IPF285.5f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 190841 192295 + orf19.3272 190841 192295 1 190841 192295 191184 192179 orf19.10782|IPF24041.1|IPF284.1|Contig4-2791_0001|Contig4-2793_0013|orf6.324|orf6.8272|CA5463|CaO19.10782|CaO19.3272|IPF284 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 191354 191908 - orf19.3271 191354 191908 1 191908 191354 191908 191354 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 192133 197679 - orf19.3269 192133 197679 1 197679 192133 197102 192180 GSL2 orf19.10779|orf19.10780|IPF23990.1|IPF279.1|Contig4-2793_0012|orf6.8269|orf6.8270|CA5461|CA5462|orf19.3270|FKS2|GSL23.5f Protein similar to beta-1,3-glucan synthase; 16 predicted membrane-spanning regions; transcription regulated by Nrg1p; very low gene expression in yeast-form and hyphal cells [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 197701 198505 - orf19.3268 197701 198505 1 198505 197701 198468 197965 TMA19|orf19.10778|IPF24053.1|IPF277.1|Contig4-2793_0010|orf6.8268|CA5460|CaO19.3268|CaO19.10778|IPF277 Ortholog of S. cerevisiae Tma19p (Ykl065cp) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 198684 199941 - orf19.3267 198684 199941 1 199941 198684 199875 198814 orf19.10777|IPF24042.1|IPF276.1|Contig4-2793_0009|orf6.8267|CA5459|CaO19.10777|CaO19.3267|IPF276 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 200025 201333 + orf19.3266 200025 201333 1 200025 201333 200129 201214 orf19.10776|IPF24039.1|IPF274.1|Contig4-2793_0006|orf6.8266|CA5458|CaO19.3266|CaO19.10776|IPF274 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 201291 201903 - orf19.3265.1 201291 201903 1 201903 201291 201735 201475 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 202223 204073 + orf19.3265 202223 204073 1 202223 204073 202224 203894 TRM1 orf19.10775|IPF24029.1|IPF272.1|Contig4-2793_0003|orf6.8265|CA5457|CaO19.10775|CaO19.3265 Protein described as an N2,N2-dimethylguanine tRNA methyltransferase; induced upon adherence to polystyrene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 204184 204428 - ntar_1170 204184 204428 1 204428 204184 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 206282 206807 + orf19.3264.1 206282 206807 1 206282 206807 206338 206502 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 207629 209365 + orf19.3264 207629 209365 1 207629 209365 207731 208729 CCE1 orf19.10774|IPF24044.1|IPF267.1|Contig4-2987_0003|orf6.8264|CA5456|CaO19.3264|CaO19.10774|IPF267 Putative Holliday junction resolving enzyme; similar to S. cerevisiae Cce1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 210190 210642 + orf19.3263 210190 210642 1 210190 210642 210190 210642 orf19.10773|IPF24061.1|IPF263.1|Contig4-2987_0006|orf6.8263|CA5455|CaO19.10773|AFF7|CaO19.3263|IPF263.3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 215629 216156 + orf19.3261 215629 216156 1 215629 216156 215629 216156 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 216643 219275 - orf19.3260 216643 219275 1 219275 216643 218979 216784 orf19.10770|IPF24007.1|IPF256.1|Contig4-2987_0013|orf6.8260|CA5453|SIS2|CaO19.3260|CaO19.10770|IPF256 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 219385 219538 + ntar_1171 219385 219538 1 219385 219538 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 219851 220092 + ntar_1172 219851 220092 1 219851 220092 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 221119 221844 + orf19.3259 221119 221844 1 221119 221844 221211 221711 orf19.10769|IPF24057.1|IPF252.1|Contig4-2987_0017|orf6.8259|CA5452|SEC11|CaO19.10769|CaO19.3259 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 221685 226135 - orf19.3256 221685 226135 1 226135 221685 226003 221882 SLN1 orf19.10766|IPF24067.1|IPF250.2|Contig4-2987_0018|Contig4-2987_0019|orf6.8256|CA5451|CaO19.10766|CaO19.3256 Histidine kinase involved in a two-component signaling pathway that regulates cell wall biosynthesis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 226515 226795 + ntar_1173 226515 226795 1 226515 226795 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 227529 228691 + orf19.3255 227529 228691 1 227529 228691 227661 228041 orf19.10765|IPF24070.1|IPF244.1|Contig4-3062_0001|orf6.8255|CaO19.3255|CaO19.10765 Transcription is regulated upon yeast-hyphal switch; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 228280 230794 - orf19.3254 228280 230794 1 230794 228280 230394 228574 orf19.10764|IPF243|IPF24018.1|IPF243.2|Contig4-3062_0003|orf6.8254|CA5450|DDR48|CaO19.10764|CaO19.3254 Protein not essential for viability; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 231335 234443 + orf19.3252 231335 234443 1 231335 234443 231768 234404 DAL81|orf19.10762|IPF23988.1|IPF236.2|Contig4-3062_0004|Contig4-3062_0007|orf6.8252|CA5449|CaO19.3252|CaO19.10762 Predicted zinc-finger protein of unknown function; has similarity to S. cerevisiae Dal81p, which is a transcription factor involved in the regulation of nitrogen-degradation genes [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 234455 235166 - orf19.3251 234455 235166 2 235166|235082 235164|234455 235166 234564 ARC19 orf19.10761|IPF24058.1|IPF235.1|Contig4-3062_0008|orf6.8251|CA5448|CaO19.10761|CaO19.3251|ARC19.3f|ARC19.exon2 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to cytochalasin D [label_first_exon=CGD label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 235393 237268 - orf19.3250 235393 237268 1 237268 235393 237207 235399 orf19.10760|IPF24017.1|IPF234.1|Contig4-3062_0009|orf6.8250|CA5447|CaO19.3250|PRP40|CaO19.10760|IPF234 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 238047 239663 + orf19.3249 238047 239663 1 238047 239663 238186 239424 LAG1 orf19.10759|IPF24037.1|IPF233.1|Contig4-3062_0013|orf6.8249|CA5446|CaO19.3249|CaO19.10759 Predicted ORF in Assemblies 19, 20 and 21; amphotericin B repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 239883 240915 + orf19.3248 239883 240915 1 239883 240915 239887 240888 orf19.10758|IPF24043.1|IPF232.1|Contig4-3062_0014|orf6.8248|CA5445|CaO19.10758|CaO19.3248|IPF232 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 240404 240770 - ntar_1174 240404 240770 1 240770 240404 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 241117 247709 + orf19.3247 241117 247709 1 241117 247709 241123 247626 orf19.10757|IPF24051.1|IPF230.2|Contig4-3062_0019|Contig4-3062_0020|orf6.8247|YJL207|CA5444|CaO19.10757|CaO19.3247|IPF230 Predicted ORF in Assemblies 19, 20 and 21; putative ortholog of S. cerevisiae Yjl207cp; likely to be essential for growth, based on an insertional mutagenesis strategy [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chrR 247354 247508 - ntar_1175 247354 247508 1 247508 247354 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 247996 250747 + orf19.3245 247996 250747 1 247996 250747 248136 250682 orf19.10755|orf19.10756|IPF24023.1|IPF228.2|Contig4-3062_0023|orf6.8245|orf6.8246|CA5442|CA5443|orf19.3246|IPF18105.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chrR 250618 251252 - orf19.3244 250618 251252 1 251252 250618 251220 250801 orf19.10754|IPF24060.1|IPF227.1|Contig4-3062_0024|orf6.8244|CA5441|CaO19.3244|CaO19.10754|IPF227 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 251417 253310 + orf19.3243 251417 253310 1 251417 253310 251463 253133 SRP54 orf19.10753|IPF24028.1|IPF225.1|Contig4-3062_0025|orf6.8243|CA5440|CaO19.3243|CaO19.10753 Predicted ORF in Assemblies 19, 20 and 21; increased transcription in ssr1 homozygous null mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 253153 254067 - orf19.3242 253153 254067 1 254067 253153 254003 253269 orf19.10752|IPF18106.2|IPF224.1|Contig4-3062_0026|orf6.8242|CA5439|CaO19.3242|TAF10|CaO19.10752|TAF25 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 254161 258542 + orf19.3241 254161 258542 1 254161 258542 254241 258494 orf19.10751|IPF24065.1|IPF223.1|Contig4-3062_0027|Contig4-3062_0028|Contig4-3062_0031|orf6.8241|CA5438|CaO19.10751|CaO19.3241|IPF223 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 258288 259663 - orf19.3240 258288 259663 1 259663 258288 259606 258566 ERG27 orf19.10750|IPF24040.1|IPF218.1|Contig4-3062_0032|orf6.8240|CA5437|CaO19.3240|CaO19.10750 3-Keto sterol reductase of ergosterol biosynthesis; acts in C-4 sterol demethylation with Erg25p and Erg26p; possible drug target, essential for viability; functional homolog of S. cerevisiae Erg27p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 259703 262405 - orf19.3239 259703 262405 1 262405 259703 262366 259805 CTF18 orf19.10749|IPF23997.1|IPF217.1|Contig4-3062_0033|orf6.8239|CA5436|CaO19.10749|CaO19.3239 Predicted ORF in Assemblies 19, 20 and 21; cell-cycle regulated periodic mRNA expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 263968 264147 + ntar_1175.5 263968 264147 1 263968 264147 263968 264147 MANUAL ANNOTATION; ntar_1176-like Ca21chrR 264674 264989 + ntar_1176 264674 264989 1 264674 264989 264754 264924 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 265499 265909 + ntar_1177 265499 265909 1 265499 265909 265566 265736 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 266302 266732 + ntar_1178 266302 266732 1 266302 266732 266394 266576 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 267180 267556 + ntar_1179.1 267180 267556 1 267180 267556 267236 267382 MANUAL ANNOTATION (edit of ntar_1179); ntar_1176-like Ca21chrR 267731 268124 + ntar_1179.2 267731 268124 1 267731 268124 267818 267994 MANUAL ANNOTATION (edit of ntar_1179); ntar_1176-like Ca21chrR 268166 268346 - ntar_1180 268166 268346 1 268346 268166 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 268400 268780 + ntar_1179.3 268400 268780 1 268400 268780 268455 268634 MANUAL ANNOTATION (edit of ntar_1179); ntar_1176-like Ca21chrR 268606 269012 - ntar_1181 268606 269012 1 269012 268606 269012 268878 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 269102 269285 - ntar_1182 269102 269285 1 269285 269102 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 269104 269505 + orf19.3238 269104 269505 1 269104 269505 269104 269505 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 269794 275150 + orf19.3237 269794 275150 1 269794 275150 269863 274998 orf19.10747|IPF24059.1|IPF204.1|Contig4-2605_0007|Contig4-2605_0008|orf6.8237|CA5435|CaO19.3237|UFD4|CaO19.10747 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 275286 276305 + orf19.3235 275286 276305 1 275286 276305 275367 276209 orf19.10745|IPF24045.1|IPF199.2|orf6.8235|CA5434|CAP01|CaO19.10745|CaO19.3235|IPF199 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 276092 276604 - orf19.3234.1 276092 276604 1 276604 276092 276559 276263 SFT1 IPF24072.1|IPF198.1|CA5433 ORF Predicted by Annotation Working Group; Plc1p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 277335 278832 + orf19.3234 277335 278832 1 277335 278832 277560 278738 OYE22 orf19.10744|IPF24038.1|IPF197.1|Contig4-2645_0002|orf6.8234|CA5432|OYE24|CaO19.3234|CaO19.10744|EBP5 Predicted ORF in Assemblies 19, 20 and 21; transcription is upregulated in both intermediate and mature biofilms [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 278767 280473 - orf19.3233 278767 280473 1 280473 278767 280419 278923 orf19.10743|IPF24033.1|IPF195.1|Contig4-2645_0003|orf6.8233|CA5431|CaO19.10743|CaO19.3233|IPF195 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 282672 284263 + orf19.3232 282672 284263 1 282672 284263 282672 284237 orf19.10742|IPF24030.1|IPF191.1|Contig4-2645_0009|orf6.8232|CA5430|CaO19.10742|TNA12|CaO19.3232|IPF191 Putative transporter; mutation confers hypersensitivity to toxic ergosterol analog; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chrR 284577 284930 - ntar_1182.5 284577 284930 1 284577 284930 284678 284869 MANUAL ANNOTATION; ntar_1176-like Ca21chrR 285238 285683 - ntar_1183 285238 285683 1 285683 285238 285610 285410 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 286171 286530 - ntar_1184 286171 286530 1 286530 286171 286449 286240 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 287150 287622 - ntar_1185 287150 287622 1 287622 287150 287450 287238 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 288106 291032 - orf19.3231 288106 291032 1 291032 288106 290913 288286 CDC27 orf19.10741|IPF23992.1|IPF185.1|Contig4-2226_0007|orf6.8231|CA5429|CaO19.3231 Predicted ORF in Assemblies 19, 20 and 21; periodic mRNA expression, peak at cell-cycle S/G2 phase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chrR 288502 288764 + ntar_1186 288502 288764 1 288502 288764 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 291254 295584 - orf19.3230 291254 295584 1 295584 291254 295246 291728 BOI2 orf19.10740|IPF24079.1|IPF179.1|Contig4-3001_0036|orf6.8230|CA5428|CaO19.3230|CaO19.10740 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to toxic ergosterol analog [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 298900 299063 + ntar_1187 298900 299063 1 298900 299063 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 299573 299878 - orf19.3229 299573 299878 1 299878 299573 299878 299573 orf19.10739|orf6.3028|CaO19.10739|CaO19.3229 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 300403 303257 + orf19.3228 300403 303257 1 300403 303257 300887 303082 orf19.10738|IPF24004.1|IPF171.2|Contig4-3001_0019|Contig4-3001_0021|Contig4-3001_0023|orf6.3027|CA1494|CaO19.10738|CaO19.3228|IPF171 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to amphotericin B [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 301860 302067 - ntar_1188 301860 302067 1 302067 301860 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 302311 305067 - orf19.3227 302311 305067 1 305067 302311 305011 303476 FTH2 orf19.10737|IPF24031.1|IPF170.2|Contig4-3001_0016|orf6.3026|CA1493|CaO19.10737|FTR3|CaO19.3227 Putative iron transporter; similar to S. cerevisiae Fth1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 305433 306424 - orf19.3226 305433 306424 1 306424 305433 306353 305775 orf19.10736|IPF24054.1|IPF168.2|Contig4-3001_0014|orf6.3025|CA1492|CaO19.3226|CaO19.10736|IPF168 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 307072 310459 - orf19.3225 307072 310459 1 310459 307072 310304 307236 CWH43 orf19.10735|IPF24088.1|IPF166.2|Contig4-3001_0010|Contig4-3001_0011|orf6.3024|CA1491|CaO19.3225|CaO19.10735|IPF166 Predicted ORF in Assemblies 19, 20 and 21; transcription is downregulated in both intermediate and mature biofilms [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 310713 311643 + orf19.3223.1 310713 311643 2 310713|310917 310835|311643 310832 311209 Predicted ORF; described as 12kDa subunit of mitochondrial NADH-ubiquinone oxidoreductase; gene has intron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 311917 313267 + orf19.3223 311917 313267 2 311917|312307 312050|313267 312004 313144 ATP3 orf19.10734|IPF163.2|IPF18904.2|ATP3.3|Contig4-3001_0004|Contig4-3001_0005|orf6.3023|orf6.1763|CA1489|CA6208|orf19.3224|ATP3.3f Predicted ORF in Assemblies 19, 20 and 21; flucytosine induced; caspofungin repressed; macrophage/pseudohyphal-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 313348 316670 - orf19.3222 313348 316670 1 316670 313348 316505 313509 orf19.10733|IPF24090.1|IPF162.2|Contig4-3001_0003|orf6.1764|orf6.3022|CA0686|CaO19.10733|CaO19.3222|IPF162 Predicted ORF in Assemblies 19, 20 and 21; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 318221 321938 + orf19.3221 318221 321938 1 318221 321938 318330 321779 CPA2 orf19.10732|IPF24081.1|IPF4967.1|Contig4-2886_0008|CA0687|CaO19.10732|CaO19.3221|orf6.1765 Predicted ORF in Assemblies 19, 20 and 21; protein detected by mass spec in stationary phase cultures; transcription is upregulated in both intermediate and mature biofilms [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 322493 324139 + orf19.2517 322493 324139 1 322493 324139 322493 324139 orf19.10053|IPF24746.1|IPF4969.2|Contig4-2537_0007|orf6.1398|CA0459|CaO19.2517|HOL3|CaO19.10053 Predicted membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 324270 325441 - orf19.2518 324270 325441 1 325441 324270 325382 324501 orf19.10054|IPF24764.1|IPF4971.1|Contig4-2537_0005|orf6.1399|CA0460|CaO19.2518|SEC17|CaO19.10054 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 325634 326322 + orf19.2519 325634 326322 1 325634 326322 325676 326266 orf19.10055|IPF24780.1|IPF4972.1|Contig4-2537_0002|orf6.1400|CA0461|CaO19.2519|NNF1|CaO19.10055|IPF4972 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 326281 327358 - orf19.2520 326281 327358 1 327358 326281 327299 326337 orf19.10056|IPF18612.2|IPF4973.1|Contig4-2537_0001|orf6.1401|orf6.3376|CA0462|CaO19.2520|MRPS28 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 327417 330536 + orf19.2521 327417 330536 1 327417 330536 327534 330467 orf19.10057|IPF4976.2|IPF29049.1|IPF18980.2|Contig4-2933_0023|Contig4-2933_0024|orf6.1402|orf6.3375|CA1739|orf19.2522 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 330695 331602 + orf19.2524 330695 331602 1 330695 331602 330757 331485 MGE1 orf19.10059|IPF24774.1|IPF4977.2|Contig4-2933_0022|orf6.3373|CA1738|CaO19.10059|CaO19.2524 Predicted ORF in Assemblies 19, 20 and 21; macrophage/pseudohyphal-repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 331883 333204 + orf19.2525 331883 333204 1 331883 333204 332030 333160 LYS12 orf19.10060|IPF24758.1|IPF4979.2|Contig4-2933_0019|Contig4-2933_0021|orf6.3372|CA1737|CaO19.2525|CaO19.10060 Protein described as mitochondrial homoisocitrate dehydrogenase; clade-associated gene expression; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 333100 334487 - orf19.2527 333100 334487 1 334487 333100 334487 333201 orf19.10062|IPF24756.1|IPF4983.1|Contig4-2933_0017|orf6.3370|CA1736|CaO19.2527|CaO19.10062|IPF4983 Predicted ORF in Assemblies 19, 20 and 21; induced upon biofilm formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chrR 334867 337026 + orf19.2528 334867 337026 1 334867 337026 334918 336906 orf19.10063|IPF24738.1|IPF4986.2|Contig4-2933_0011|Contig4-2933_0014|orf6.3369|CA1735|CaO19.10063|BDP1|CaO19.2528|IPF4986 Predicted ORF in Assemblies 19, 20 and 21; flucytosine repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 337166 338067 + orf19.2529 337166 338067 1 337166 338067 337266 337883 orf19.10064|IPF24781.1|IPF4988.1|Contig4-2933_0010|orf6.3368|CA1734|CaO19.2529|GPI15|CaO19.10064|IPF4988 Predicted ORF in Assemblies 19, 20 and 21; shares similarity with human Pig-H, which is involved in glycosylphosphatidylinositol assembly [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 337791 338514 - orf19.2529.1 337791 338514 1 338514 337791 338431 338186 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chrR 338612 339111 + ntar_1189 338612 339111 1 338612 339111 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 338784 339126 - ntar_1190 338784 339126 1 339126 338784 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 339497 339612 - tl(uaa)2 339497 339612 2 339612|339542 339574|339497 tL(UAA)2.2 tRNA-Leu predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 340533 340865 - orf19.2530 340533 340865 1 340865 340533 340865 340533 orf19.10065|orf6.2389|CaO19.10065|CaO19.2530 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 340825 342185 + orf19.2531 340825 342185 1 340825 342185 341036 342001 CSP37 orf19.10066|orf6.2388|IPF24765.1|IPF4991.2|Contig4-2933_0007|CA1075|CaO19.10066|CaO19.2531|IPF4991 Plasma membrane, hyphal cell wall protein; role in progression of murine systemic infection; predicted P-loop, divalent cation binding, N-glycosylation sites; expressed in yeast and hyphae; hyphal downregulated; lacks S. cerevisiae homolog [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 342394 344292 + orf19.2532 342394 344292 1 342394 344292 342526 344253 PRS orf19.10067|orf19.10068|PRSCa|IPF24786.1|IPF24759.1|IPF4992.1|IPF4994.1|Contig4-2933_0005|Contig4-2933_0006|orf6.2387|orf6.2386|CA1074|CA1073|orf19.2533|PRORS.5f Putative prolyl-tRNA synthetase; monofunctional Class II synthetase; gene is constitutively expressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 344032 345023 - orf19.2533.1 344032 345023 2 345023|344767 344858|344032 344860 344483 IPF24724.1|IPF4995.1|Contig4-2933_0004|CA1072|SBH1 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 345663 348709 + orf19.2534 345663 348709 1 345663 348709 345905 348490 PIN4 orf19.10069|IPF24728.1|IPF16624.2|Contig4-2933_0003|orf6.2385|orf6.364|CA1071|CaO19.2534|IPF16624 Protein with similarity to S. cerevisiae Pin4p; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 349046 349387 - orf19.2537 349046 349387 1 349387 349046 349387 349046 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 349327 351775 + orf19.2538 349327 351775 1 349327 351775 349638 351389 PTC2 orf19.10072|IPF24743.1|IPF17818.3|Contig4-3095_0030|orf6.2347|orf6.299|orf6.366|CA0047|CaO19.2538|IPF17818.2 Putative protein phosphatase of the Type 2C-related family (serine/threonine-specific), similar to S. cerevisiae Ptc2p and Ptc3p; mutant shows virulence defect [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 351992 352384 + ntar_1191 351992 352384 1 351992 352384 352235 352384 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 352941 353276 - orf19.2539 352941 353276 1 353276 352941 353276 352941 orf19.10073|IPF24810.1|IPF29071.1|orf6.2348|CaO19.2539|CaO19.10073 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 353057 355887 + orf19.2540 353057 355887 1 353057 355887 353353 355770 SAS3 orf19.10074|IPF24731.1|IPF16878.2|Contig4-2043_0003|orf6.2349|CA1054|CaO19.10074|CaO19.2540 Similar to silencing proteins; increased transcription is observed upon fluphenazine treatment [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 355896 357304 - orf19.2541 355896 357304 1 357304 355896 357231 355987 orf19.10075|IPF24755.1|IPF17504.2|Contig4-2043_0005|orf6.2350|CA1055|CaO19.2541|CaO19.10075|IPF17504 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 357258 358371 + orf19.2542 357258 358371 1 357258 358371 357411 358157 orf19.10076|IPF24772.1|IPF17503.1|Contig4-1647_0003|orf6.2351|CA1056|CaO19.10076|CaO19.2542|IPF17503 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 357451 357644 - ntar_1192 357451 357644 1 357644 357451 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 358460 359767 + orf19.2544 358460 359767 1 358460 359767 358529 359125 orf19.10078|IPF24783.1|IPF17031.2|Contig4-2742_0011|orf6.2353|CA1057|CaO19.10078|PTH2|CaO19.2544|IPF17031 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 359194 361273 - orf19.2545 359194 361273 1 361273 359194 361143 359341 DOT6 orf19.10079|IPF24744.1|IPF19898.1|Contig4-2742_0009|orf6.2354|CA1058|CaO19.2545|CaO19.10079 Predicted ORF in Assemblies 19, 20 and 21; repressed upon high-level peroxide stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 361568 363549 - orf19.2546 361568 363549 2 363549|363443 363514|361568 363519 361881 TRP2 orf19.10080|IPF13684.2|IPF19073.2|Contig4-2742_0007|orf6.1008|orf6.2355|CA1059|CaO19.2546 Predicted ORF in Assemblies 19, 20 and 21; regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 361933 362168 + ntar_1193 361933 362168 1 361933 362168 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 363741 366841 - orf19.2547 363741 366841 1 366841 363741 366790 363830 orf19.10081|IPF11552.2|IPF13683.2|Contig4-2742_0006|orf6.1007|orf6.1713|orf6.2356|CA0260|CaO19.2547|IPF13683 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 366989 368216 - orf19.2549 366989 368216 1 368216 366989 368157 367042 orf19.10082|IPF11553.2|IPF13681.2|IPF19074.1|Contig4-2742_0003|orf6.1005|orf6.1714|orf6.1004|CA0652|orf19.2550 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 368383 371126 - orf19.2551 368383 371126 1 371126 368383 371056 368753 MET6 orf19.10083|METE|IPF11555.2|IPF29050.1|Contig4-2742_0001|orf6.1715|CA0653|CaO19.10083|CaO19.2551 Essential 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase (cobalamin-independent methionine synthase); antigenic during murine or human systemic infection; heat shock, estrogen, possibly biofilm, and GCN-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 371522 375224 + ntar_1194 371522 375224 1 371522 375224 373886 374080 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 372030 374003 - orf19.2552 372030 374003 1 374003 372030 374003 372039 orf19.10084|IPF11557.2|IPF11560.1|IPF19449.2|IPF29057.1|IPF11550.3f|orf6.1716|orf6.87|CA0654 Protein similar to S. cerevisiae Pmr1p; amphotericin B induced; previously merged with orf19.2553; unmerged from orf19.2553 in a revision of Assembly 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chrR 374217 375284 - orf19.2553 374217 375284 1 375284 374217 375284 374217 orf19.10085|IPF11560.1|IPF11560.5f|orf6.1717|CA0655|CaO19.2553|ACU1|CaO19.10085 Protein similar to S. cerevisiae Pmr1p; amphotericin B induced; previously merged with orf19.2552 in Assembly 20; unmerged from orf19.2552 in a revision of Assembly 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 377185 378143 + orf19.2555 377185 378143 1 377185 378143 377252 377908 URA5 orf19.10087|IPF18913.2|IPF7845.2|Contig4-3016_0027|orf6.3804|orf6.1719|CA2056|CaO19.2555 Protein abundance is affected by URA3 expression in the CAI-4 strain background; flucytosine induced; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 377858 378903 - orf19.2557 377858 378903 1 378903 377858 378851 378024 SEC65 orf19.10089|IPF24769.1|IPF7847.1|Contig4-3016_0025|orf6.3806|CA2057|CaO19.2557|CaO19.10089 Functional homolog of S. cerevisiae Sec65p, which is a component of the protein-targeting Signal Recognition Particle (SRP); similar to mammalian Srp19; transcription is positively regulated by Tbf1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 379107 380835 + orf19.2558 379107 380835 1 379107 380835 379275 380723 orf19.10090|IPF24748.1|IPF7848.1|Contig4-3016_0024|orf6.3807|CA2058|CaO19.10090|CaO19.2558|IPF7848 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 380685 383685 - orf19.2559 380685 383685 1 383685 380685 383139 380833 CDC4 orf19.10091|IPF24734.1|IPF7849.2|Contig4-3016_0022|orf6.3808|CA2059|CaO19.10091|CaO19.2559 F-box subunit of SCF(CDC4) ubiquitin ligase; functional homolog of S. cerevisiae Cdc4p; mutation or depletion causes hyperfilamentation; nonessential; Sol1p is a substrate of SCF-Cdc4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 384118 387635 - orf19.2560 384118 387635 1 387635 384118 387582 384289 CDC60 orf19.10092|orf19.10094|IPF24782.1|IPF24722.1|IPF7853.2|IPF7856.2|Contig4-3016_0017|Contig4-3016_0020|Contig4-3016_0021|orf6.3809|orf6.3811|CA2060|CA2061|orf19.2562|CDC60B|CDC61.3f Cytosolic leucyl tRNA synthetase; has conserved amino acid and ATP binding class I signature, tRNA binding, and proofreading motifs; likely essential for growth; interacts with benzoxaborole antifungals; similar to S. cerevisiae Cdc60p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 387723 390640 - orf19.2563 387723 390640 1 390640 387723 390593 387846 orf19.10095|IPF24723.1|IPF7858.2|Contig4-3016_0015|orf6.3812|CA2062|PRP24|CaO19.10095|CaO19.2563|IPF7858 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 390664 391652 + orf19.2564 390664 391652 1 390664 391652 390664 391527 orf19.10096|IPF24768.1|IPF7859.2|Contig4-3016_0014|orf6.3813|CA2063|CaO19.2564|CaO19.10096|IPF7859 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 391700 394929 + orf19.2565 391700 394929 1 391700 394929 391753 394851 orf19.10097|IPF19597.2|IPF29077.1|Contig4-3016_0012|orf6.3814|orf6.640|CA0140|MDM1|CaO19.2565|MDM1.3|IPF19597.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 395308 396294 + orf19.2568 395308 396294 1 395308 396294 395483 396193 IFU5 orf19.10100|YFL010C|YLR63|IPF19838.2|IPF19956.2|Contig4-3016_0009|orf6.4669|orf6.637|CA2679|CaO19.2568|IPF19956.1 Predicted membrane protein; estradiol-induced; increased transcription is associated with CDR1 and CDR2 overexpression or fluphenazine treatment; gene has putative drug-responsive regulatory site; similar to S. cerevisiae Wwm1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 396398 397099 + orf19.2570 396398 397099 1 396398 397099 396477 396896 MCI4 orf19.10102|IPF24789.1|IPF2728.2|Contig4-3016_0007|orf6.4671|CA2680|CaO19.2570|CaO19.10102 Protein described as NADH-ubiquinone dehydrogenase; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 396903 398217 - orf19.2571 396903 398217 1 398217 396903 397884 397252 SEC4 orf19.10103|IPF24779.1|IPF2730.1|Contig4-3016_0005|orf6.4672|CA2681|CaO19.10103|CaO19.2571 Small GTPase of Rab family; role in secretion, post-Golgi; possible C-terminal palmitoylation; downregulated on adherence to polystyrene; not regulated on white-opaque or yeast-hyphal switching; functional homolog of S. cerevisiae Sec4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 398559 400525 - orf19.2573 398559 400525 1 400525 398559 400470 398692 FRS1 orf19.10105|IPF24745.1|IPF2731.2|Contig4-3016_0002|orf6.4674|CA2682|CaO19.2573|CaO19.10105 Protein similar to the beta subunit of S. cerevisiae phenylalanyl-tRNA synthetase; possible role in early cell wall biosynthesis; translation-related genes are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 400694 404316 - orf19.2574 400694 404316 1 404316 400694 403453 400733 orf19.10106|IPF24725.1|IPF2734.2|orf6.4675|CA2683|CaO19.2574|CaO19.10106|IFU4 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 401885 402022 + ntar_1195 401885 402022 1 401885 402022 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 404431 405615 + orf19.2575 404431 405615 1 404431 405615 404543 405502 orf19.10107|IPF24766.1|IPF2736.2|Contig4-2970_0001|orf6.4676|CA2684|CaO19.10107|CaO19.2575|IFU3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 405443 407958 - orf19.2579 405443 407958 1 407958 405443 407914 405503 orf19.10111|IPF24730.1|IPF2741.2|Contig4-2970_0003|orf6.4680|CA2685|MSH4|CaO19.2579|CaO19.10111 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 408016 409180 - orf19.2580 408016 409180 1 409180 408016 409030 408035 HST2 orf19.10112|IPF24762.1|IPF2743.2|Contig4-2970_0004|orf6.4681|CA2686|CaO19.2580|CaO19.10112 Putative histone deacetylase, involved in regulation of white-opaque switching; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 409241 410236 - orf19.2581 409241 410236 1 410236 409241 410236 409241 orf19.10113|IPF18435.2|IPF2744.2|Contig4-2970_0006|orf6.4682|CA2688|CaO19.2581|CaO19.10113|IFU6.5f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chrR 410490 414046 + orf19.2582 410490 414046 1 410490 414046 410669 413725 orf19.10114|IPF24816.1|IPF2746.2|Contig4-2970_0008|Contig4-2970_0009|orf6.4683|CA2689|CaO19.2582|CaO19.10114|IFU2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 414016 415971 - orf19.2583 414016 415971 2 415971|414462 414547|414016 415971 414016 orf19.10115|IPF24751.1|IPF2749.2|Contig4-2970_0012|Contig4-2970_0013|orf6.4684|orf19.2582.1|PTR2|CA2691|CA2690|PTR2.exon2|IPF2747.1|PTR2.exon1 [NOT TRANSCRIBED?] Putative oligopeptide transporter [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 417074 417644 + orf19.2583.1 417074 417644 1 417074 417644 417463 417588 IPF2751.1 Pseudogene; formerly an ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=true scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 417585 417839 - orf19.2583.2 417585 417839 1 417839 417585 417839 417585 IPF24809.1|IPF2752.1 Pseudogene; formerly an ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 417907 418705 + orf19.2584 417907 418705 2 417907|417980 417921|418705 417907 418705 OPT9 orf19.10116|IPF24775.1|IPF2753.1|Contig4-2970_0018|orf6.4685|OPT3|CA6204|psiOPT1 Probable pseudogene similar to fragments of OPT1 oligopeptide transporter gene; decreased expression in hyphae compared to yeast-form cells; transcriptionally induced upon phagocytosis by macrophage [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 418965 419665 - orf19.2585 418965 419665 1 419665 418965 419555 418965 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chrR 419892 420208 - ntar_1196 419892 420208 1 420208 419892 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 420652 422288 - orf19.2587 420652 422288 1 422288 420652 422258 420762 HNM3 orf19.10118|IPF2778.2|IPF2781.2|Contig4-2970_0020|Contig4-2970_0022|orf6.4112|CA2276|CaO19.2587|CaO19.10118 Predicted ORF in Assemblies 19, 20 and 21; flucytosine repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 421547 421763 + ntar_1197 421547 421763 1 421547 421763 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 421916 422376 + ntar_1198 421916 422376 1 421916 422376 422065 422376 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 422446 423187 - orf19.2590 422446 423187 1 423187 422446 423120 422482 orf19.10121|IPF24778.1|IPF2776.2|Contig4-2970_0024|orf6.4108|CA2275|CaO19.10121|BIO4|CaO19.2590 Putative protein of unknown function, transcription is upregulated in clinical isolates from HIV+ patients with oral candidiasis; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 423357 424869 + orf19.2591 423357 424869 1 423357 424869 423370 424671 orf19.10122|IPF24754.1|IPF2774.2|Contig4-2970_0025|orf6.4107|CA2274|BIO31|CaO19.2591|CaO19.10122|BIO3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 425095 426364 - orf19.2593 425095 426364 1 426364 425095 426350 425226 BIO2 orf19.10124|orf6.4105|IPF24757.1|IPF2771.2|Contig4-2821_0003|Contig4-2970_0027|CA2273|CaO19.10124|CaO19.2593 Protein described as biotin synthase; transcriptionally upregulated in high iron; transcription is downregulated in response to treatment with ciclopirox olamine; upregulated in clinical isolates from HIV+ patients with oral candidiasis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 427363 428545 + orf19.2594 427363 428545 1 427363 428545 427492 428391 orf19.10125|orf19.10126|IPF24767.1|IPF19945.1|Contig4-2821_0006|orf6.4104|orf6.4103|CA2272|orf19.2595|CaO19.10125|RPA43|CaO19.2594 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 428368 430072 - orf19.2597 428368 430072 1 430072 428368 429937 428531 MRS2 orf19.10128|IPF24752.1|IPF2765.2|Contig4-2821_0007|orf6.4101|CA2271|CaO19.10128|CaO19.2597 Putative magnesium ion transporter, mitochondrial; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 430166 431113 - orf19.2598 430166 431113 2 431113|430962 431031|430166 431051 430303 VMA4 orf19.10129|IPF24776.1|IPF2763.1|Contig4-2821_0009|orf6.4100|CA2270 Transcription is regulated by Mig1p; caspofungin repressed; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 431327 432400 - orf19.2599 431327 432400 1 432400 431327 432233 431379 orf19.10130|IPF24770.1|IPF2761.1|Contig4-2821_0010|orf6.4099|CA2269|CaO19.10130|CRC1|CaO19.2599|YOR100 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 433027 433315 + ntar_1199 433027 433315 1 433027 433315 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 433115 435687 - orf19.2600 433115 435687 1 435687 433115 435586 433229 SPC98 orf19.10131|IPF24726.1|IPF24736.1|IPF18497.1|IPF2757.2|Contig4-2821_0016|orf6.4098|CA2267|IFU1.5f Predicted ORF in Assemblies 19, 20 and 21; periodic mRNA expression, peak at cell-cycle S/G2 phase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 435920 438028 - orf19.2601 435920 438028 1 438028 435920 437760 436066 HEM1 orf19.10132|orf6.3598|IPF2755.3|IPF29053.1|Contig4-2821_0018|orf6.4097|CA2266|CaO19.2601|IPF2755.2 Protein described as 5-aminolevulinate synthase; transcriptionally regulated by iron; caspofungin repressed; expression greater in high iron; regulated by Ssn6p; induced by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 440892 443243 - orf19.2602 440892 443243 1 443243 440892 443243 440892 OPT1 orf19.10133|IPF24733.1|IPF14139.2|Contig4-1813_0003|Contig4-2970_0016|orf6.3597|CA1902|CaO19.2602|CaO19.10133 Oligopeptide transporter; transports 3-to-5-residue peptides; alleles are distinct, one has intron; not ABC or PTR type transporter; suppresses S. cerevisiae ptr2-2 mutant defects; induced by BSA or peptides; Stp3p, Hog1p regulated [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chrR 444934 446709 - orf19.2604 444934 446709 1 446709 444934 446709 445213 orf19.10135|IPF24750.1|IPF14135.2|Contig4-1720_0004|orf6.3595|CA1901|CaO19.10135|CaO19.2604|IPF14135 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 447056 449309 + orf19.2605 447056 449309 1 447056 449309 447156 449228 orf19.10136|IPF24740.1|IPF14133.2|Contig4-2304_0006|Contig4-2304_0007|orf6.3594|CA1900|CaO19.2605|PRK1|CaO19.10136|ARK1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 449280 452127 - orf19.2606 449280 452127 1 452127 449280 451924 449423 HDA1 orf19.10137|IPF24729.1|IPF15480.2|Contig4-2304_0003|orf6.3593|CA1899|CaO19.2606|CaO19.10137 Histone deacetylase; regulates frequency of white-to-opaque switching, but not opaque-to-white switching; greater expression in white cells than opaque cells; has conserved deacetylation motif; inhibited by trichostatin-A [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 452838 454072 + orf19.2607 452838 454072 1 452838 454072 452963 453886 orf19.10138|IPF15672.2|IPF29058.1|Contig4-2025_0001|orf6.3592|orf6.4278|CA2392|PMU4|CaO19.2607|IPF15672|IPF15672.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 453895 455363 - orf19.2608 453895 455363 1 455363 453895 455102 454023 ADH5 orf19.10139|IPF24761.1|IPF15671.2|Contig4-2025_0002|orf6.4277|CA2391|CaO19.10139|SAD1|CaO19.2608 Putative alcohol dehydrogenase; soluble protein in hyphae; expression is regulated upon white-opaque switching; fluconazole-induced; antigenic during murine systemic infection; regulated by Nrg1p, Tup1p; macrophage-downregulated protein [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chrR 456557 456677 + tl(aag)1 456557 456677 2 456557|456632 456593|456677 tL(AAG)1.2 tRNA-Leu predicted by tRNAscan-SE; has atypical G at position 32 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 456750 458466 - orf19.2609 456750 458466 1 458466 456750 458440 456878 CET1 orf19.10140|IPF24749.1|IPF8499.1|Contig4-2859_0011|orf6.4276|CA2390|CaO19.10140|CaO19.2609 mRNA 5'-triphosphatase; large subunit of mRNA capping enzyme; positively regulates Ceg1p activity; functional homolog of S. cerevisiae Cet1p; Cet1p and Cgt1p form a 2:1 complex [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 458667 459443 - orf19.2610 458667 459443 2 459443|459328 459385|458667 459418 458814 orf19.10141|IPF24787.1|IPF8500.2|Contig4-2859_0009|orf6.4275|CA2389|CaO19.2610|ARC2|CaO19.10141|IPF8500 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 459613 462420 + orf19.2611 459613 462420 1 459613 462420 459676 462318 MCM6 orf19.10142|IPF24727.1|IPF8502.2|Contig4-2859_0007|orf6.4274|CA2388|CaO19.10142|CaO19.2611 Protein described as part of MCM DNA replication initiation complex; mRNA expression, peak at cell-cycle M/G1 phase; regulated by tyrosol and cell density; repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 462311 463173 - orf19.2612 462311 463173 1 463173 462311 463126 462374 orf19.10143|IPF24773.1|IPF8504.2|Contig4-2859_0006|orf6.4273|CA2387|CaO19.2612|CaO19.10143|IPF8504 Putative transcription factor with zinc finger DNA-binding motif; decreased expression observed in an ssr1 homozygous null mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 463603 465196 + orf19.2613 463603 465196 2 463603|463805 463723|465196 463715 464800 ECM4 orf19.10144|IPF24763.1|IPF8505.2|Contig4-2859_0005|orf6.4272|ECM41|CA2386|ECM41.3f|ECM41.3 Protein similar to S. cerevisiae Ecm4p; transcription is regulated by Nrg1p and Tup1p; induced in core stress response or in cyr1 or ras1 homozygous null mutant (yeast-form or hyphal cells); transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 465361 466405 + orf19.2614 465361 466405 2 465361|465544 465469|466405 465463 466283 RSR1 orf19.10145|IPF24771.1|IPF8507.2|Contig4-2859_0002|orf6.4271|CA2385|RSR1.3 RAS-related protein; GTP/GDP cycling required for wild-type polar bud site selection, hyphal growth guidance; role in systemic virulence in mouse; geranylgeranylation predicted; suppresses S. cerevisiae cdc24-4 mutant heat sensitivity [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 467097 469552 + orf19.2615 467097 469552 1 467097 469552 467268 469325 MDL1 orf19.10146|IPF24739.1|IPF7801.2|Contig4-2761_0014|orf6.4270|CA2384|CaO19.10146|CaO19.2615 Putative mitochondrial, half-size MDR-subfamily ABC transporter [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 469505 469784 - ntar_1200 469505 469784 1 469784 469505 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 470002 470442 - ntar_1201 470002 470442 1 470442 470002 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 470508 475094 + orf19.2616 470508 475094 1 470508 475094 470546 475087 UGT51C1 orf19.10147|IPF24795.1|IPF7800.3|Contig4-2761_0001|orf6.1655|orf6.4269|CA0618|UGT51|CaO19.2616|IPF7800.2 UDP-glucose:sterol glucosyltransferase; enzyme of sterol glucoside (membrane-bound lipid) biosynthesis; has UDP-sugar binding domain; activity is UDP-glucose-specific in vitro; enzyme does not use UDP-mannose; Mig1p-regulated gene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chrR 474972 475144 - ntar_1202 474972 475144 1 475144 474972 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 475581 477084 + orf19.2618 475581 477084 1 475581 477084 475617 476846 MET2 orf19.10149|IPF24760.1|IPF7797.2|Contig4-2761_0004|orf6.1653|CA0617|CaO19.10149|CaO19.2618 Putative homoserine acetyltransferase; Gcn4p-regulated; macrophage/pseudohyphal-repressed; not greatly biofilm induced, in contrast to many sulfur amino acid metabolic genes; no human or murine homolog; virulence-group-correlated expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 477687 479522 + orf19.2619 477687 479522 1 477687 479522 478042 479430 PHO113 orf19.11238|orf19.10150|orf6.4212|IPF24753.1|IPF7796.2|IPF23531.1|IPF28658.1|PHO11|Contig4-2761_0007|orf6.1652|CA0616|orf19.3754|PHO111|CaO19.2619|CaO19.10150 Protein described as a constitutive acid phosphatase; transcription is negatively regulated by Rim101p; DTT-extractable; N-glycosylated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chrR 479560 482674 - orf19.3753 479560 482674 1 482674 479560 482445 479692 SEF1 orf19.11237|IPF23521.1|IPF7790.2|Contig4-2761_0009|Contig4-2761_0013|orf6.4213|CA2346|CaO19.11237|CaO19.3753 Putative transcription factor with zinc cluster DNA-binding motif; transcription is negatively regulated by Sfu1p and positively regulated by Tbf1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 483873 485184 - orf19.3752 483873 485184 1 485184 483873 485125 484040 RAD51 orf19.11236|IPF15096.2|IPF7787.2|Contig4-1795_0004|Contig4-1795_0005|orf6.4214|orf6.615|CA2347|CaO19.3752 Predicted ORF in Assemblies 19, 20 and 21; flucytosine induced; slow growth and increased white-to-opaque switching frequency in null mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 489927 493803 + orf19.3751 489927 493803 1 489927 493803 490320 493304 orf19.11235|IPF23518.1|IPF12811.2|Contig4-2818_0016|orf6.4215|CA2348|CaO19.11235|CaO19.3751|IPF12811 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 493904 496679 - orf19.3749 493904 496679 1 496679 493904 496621 493904 IFC3 IPF4737.2|IPF12812.3|Contig4-2818_0020|orf6.5478|OPT3|CA2349|OPT21|CaO19.3749|IPF12812.2 Oligopeptide transporter; transcriptionally induced upon phagocytosis by macrophage; induced by BSA or peptides; fluconazole-induced; upregulated by Rim101p at pH 8; virulence-group-correlated expression; no human or murine homolog [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chrR 497850 498170 + orf19.3748 497850 498170 1 497850 498170 497850 498170 IPF23545.1|orf6.46|orf6.5477|CaO19.3748 ORF Predicted by Annotation Working Group; orf19.3747 and orf19.3748 are short, overlapping ORFs in intergenic region between two oligopeptide transporter-encoding genes [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 499916 502705 - orf19.3746 499916 502705 1 502705 499916 502705 499916 IFC1 orf19.11233|IPF23519.1|IPF4732.2|IPF4737.2|OPT2|Contig4-2422_0002|orf6.5478|CA3257|CA3258|CaO19.11231|OPT22|CaO19.3746|IFC2|orf6.5476 Oligopeptide transporter; transcriptionally induced upon phagocytosis by macrophage; macrophage/pseudohyphal-repressed after 16h; fluconazole-induced; virulence-group-correlated expression; fungal-specific (no human or murine homolog) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chrR 504591 507048 - orf19.3744 504591 507048 1 507048 504591 507024 504787 orf19.11229|IPF4730.2|IPF28654.1|Contig4-3070_0001|orf6.5474|CA3256|CaO19.3744|IPF4730 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 507338 508544 - orf19.3743 507338 508544 1 508544 507338 508478 507459 orf19.11228|IPF23535.1|IPF4729.2|Contig4-3070_0003|orf6.5473|CA3255|CaO19.3743|CaO19.11228|IPF4729 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 508625 509480 - orf19.3742 508625 509480 1 509480 508625 509367 508642 orf19.11227|IPF4728.1|IPF19450.2|Contig4-3070_0005|orf6.5472|orf6.81|CA3254|CaO19.3742|IPF4728 Predicted ORF in Assemblies 19, 20 and 21; expression regulated during planktonic growth; greater mRNA abundance observed in a cyr1 homozygous null mutant than in wild type; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 510390 511421 + orf19.3740 510390 511421 1 510390 511421 510509 511357 PGA23 orf19.11225|orf6.5470|IPF4724.1|IPF19822.2|Contig4-3070_0007|orf6.83|CA3253|PGR23|SLP99|CaO19.3740|IPF4724 Putative GPI-anchored protein of unknown function; transcription is negatively regulated by Rim101p; regulated by Cyr1p; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chrR 511782 512291 + orf19.3738 511782 512291 1 511782 512291 511782 512291 PGA22 orf19.11223|IPF23538.1|IPF4722.1|Contig4-3070_0008|orf6.5468|CA3252|CaO19.11223|CaO19.3738|IPF4722 [NOT TRANSCRIBED?] Putative GPI-anchored protein of unknown function [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 512357 515002 - orf19.3737 512357 515002 1 515002 512357 514916 512535 orf19.11222|IPF4721|IPF23523.1|IPF4721.2|Contig4-3070_0009|orf6.5467|CA3251|CaO19.11222|CaO19.3737 Predicted ORF in Assemblies 19, 20 and 21; transcription is downregulated in response to treatment with ciclopirox olamine [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 515706 516217 + ntar_1203 515706 516217 1 515706 516217 515706 515828 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 515749 515822 - tv(aac)3 515749 515822 1 515822 515749 tV(AAC)3.2 tRNA-Val predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 515920 516275 - ntar_1204 515920 516275 1 516275 515920 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 516524 517370 + ntar_1423 516524 517370 2 516524|516775 516552|517370 516867 517160 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chrR 516764 517873 - orf19.3736 516764 517873 1 517873 516764 517873 516764 KAR4 orf19.11221|IPF23534.1|IPF4719.2|Contig4-3070_0014|orf6.1096|orf6.5466|CA0307|CaO19.3736|IPF4719 Protein similar to S. cerevisiae Kar4p, which has a role in karyogamy; transcription is opaque-specific, a-specific, and induced by alpha factor [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 518256 519583 + orf19.3735 518256 519583 2 518256|518435 518363|519583 518256 519583 orf19.11220|IPF4716.2|IPF19050.1|Contig4-3070_0017|orf6.1097|orf6.5465|CA3250|CaO19.3735|IPF4716 Predicted ORF in Assemblies 19, 20 and 21; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 519843 523087 - orf19.3734 519843 523087 1 523087 519843 522632 520053 GEF2 orf19.11219|IPF9175.2|IPF4715.3|Contig4-3070_0020|orf6.1098|orf6.5464|CA3249|GEF12|CaO19.3734|GEF2.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chrR 525346 526951 + orf19.3733 525346 526951 1 525346 526951 525552 526790 IDP2 orf19.11218|IPF9177.2|Contig4-3070_0023|orf6.1691|orf6.5462|CA0643|CaO19.3733 Putative isocitrate dehydrogenase; expression is regulated upon white-opaque switching; shows colony morphology-related gene regulation by Ssn6p; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 526860 527029 - ntar_1205 526860 527029 1 527029 526860 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 527495 528813 + orf19.3732 527495 528813 1 527495 528813 527711 528637 ERG25 orf19.11216|ERG251|IPF23536.1|IPF9179.2|Contig4-3070_0024|orf6.1690|CA0642|CaO19.11216|CaO19.3732 Putative C-4 methyl sterol oxidase with role in C4-demethylation of ergosterol biosynthesis intermediates, based on similarity to S. cerevisiae Erg25p; fluconazole-induced; upregulated in biofilm and in azole-resistant strain [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 528697 529351 - orf19.3730 528697 529351 1 529351 528697 529241 528834 orf19.11214|orf6.1688|IPF7347.1|IPF9181.1|Contig4-3070_0026|orf6.1829|CA0727|CaO19.3730|IPF7347 Protein similar to S. cerevisiae Kre27p, which has a role in resistance to killer toxin; predicted Kex2p substrate [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 529900 533305 + orf19.3728 529900 533305 2 529900|533163 532611|533305 530049 533305 orf19.11212|IPF7345.2|IPF28652.1|Contig4-3070_0030|Contig4-3070_0032|orf6.1687|orf6.1831|orf6.896|CA0728|IPF7345 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGD orf_changed=false scenario_first_exon=A scenario_last_exon=Z] Ca21chrR 533720 535175 + orf19.3727 533720 535175 1 533720 535175 533720 535105 PHO112 orf19.11211|orf6.897|IPF23530.1|IPF7341.2|PHO3|PHO11|PHO12|Contig4-3070_0034|orf6.1832|CaO19.3727 Protein described as a constitutive acid phosphatase; transcription is negatively regulated by Rim101p; DTT-extractable; N-glycosylated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chrR 535337 538515 + orf19.3726 535337 538515 1 535337 538515 535398 538388 orf19.11210|IPF7338.2|IPF19851.2|Contig4-3070_0035|orf6.1833|orf6.898|CA0729|CaO19.3726|IPF7338 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 538694 539751 + orf19.3724 538694 539751 1 538694 539751 538767 539576 orf19.11208|IPF7334.1|IPF28659.1|Contig4-3070_0036|orf6.1835|CA0730|CaO19.3724|IPF7334 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 539601 542257 - orf19.3722 539601 542257 1 542257 539601 542237 539688 orf19.11206|IPF7333.3|IPF28653.1|Contig4-3070_0037|orf6.1837|CA0731|CaO19.3722|FAP1|IPF7333|IPF7333.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 542276 543489 + orf19.3721 542276 543489 1 542276 543489 542602 542955 orf19.11205|IPF23542.1|IPF28664.1|CaO19.11205|CaO19.3721 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chrR 542672 542984 - ntar_1206 542672 542984 1 542984 542672 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 543409 543887 - ntar_1207 543409 543887 1 543887 543409 543878 543702 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 544142 544407 + ntar_1208 544142 544407 1 544142 544407 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 544662 546964 + orf19.3720 544662 546964 1 544662 546964 544684 546849 orf19.11204|IPF23525.1|IPF18822.1|Contig4-2685_0003|orf6.2193|CA0961|CaO19.3720|CaO19.11204|IPF18822 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 547238 547522 + ntar_1209 547238 547522 1 547238 547522 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 548260 548730 + orf19.3719 548260 548730 1 548260 548730 548260 548730 orf19.11203|IPF27517.1|IPF23537.1|IPF12067.2|Contig4-2685_0006|Contig4-2818_0022|orf6.1363|orf6.2194|orf19.2291|CaO19.3719|CaO19.11203 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 549251 552193 + orf19.176 549251 552193 1 549251 552193 549295 552009 OPT4 orf19.11202|orf19.7809|IPF27144.1|IPF18680.1|IPF12066.2|IPF23532.1|IPF18818.2|orf6.2912|orf6.1364|orf6.4217|orf6.5478|orf6.2195|CA0442|orf19.3718|orf19.2292|OPT232|CaO19.176|CaO19.7809 Oligopeptide transporter; detected at germ tube plasma membrane by mass spectrometry; transcriptionally induced upon phagocytosis by macrophage; fungal-specific (no human or murine homolog); merged with orf19.2292 in Assembly 20 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chrR 552413 554558 + orf19.175 552413 554558 1 552413 554558 552466 554016 orf19.7808|IPF27142.1|IPF17296.2|IPF12064.1|Contig4-2484_0002|Contig4-2484_0004|orf6.2911|orf6.1365|orf6.1366|CA1419|orf19.2293|orf19.2294|CaO19.7808|CaO19.175|IPF17296 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 553464 553701 - ntar_1210 553464 553701 1 553701 553464 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 553804 554069 - ntar_1211 553804 554069 1 554069 553804 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 554735 554995 + ntar_1212 554735 554995 1 554735 554995 554735 554911 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 554809 555240 - ntar_1213 554809 555240 1 555240 554809 555240 555100 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 555188 555595 + ntar_1214 555188 555595 1 555188 555595 555188 555322 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 555291 556047 - ntar_1215 555291 556047 1 556047 555291 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 556261 556450 - ntar_1216 556261 556450 1 556450 556261 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 556918 560483 + orf19.173 556918 560483 1 556918 560483 556961 560263 orf19.7806|orf19.7807|IPF12061.3|IPF27145.1|IPF19915.1|IPF16124.2|Contig4-2440_0003|orf6.2910|orf6.2909|orf6.51|CA1418|CA0007|orf19.174|IPF12061.3f|IPF16124 Putative transcription factor with zinc finger DNA-binding motif; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 560769 561492 + orf19.172 560769 561492 1 560769 561492 560836 561231 RPC19 orf19.7805|IPF27146.1|IPF16126.1|Contig4-2440_0002|orf6.2908|CA1417|CaO19.172|CaO19.7805|IPF16126 Predicted ORF in Assemblies 19, 20 and 21; transcription is upregulated in both intermediate and mature biofilms [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 561888 564836 + orf19.171 561888 564836 2 561888|564311 563247|564836 561933 564684 DBP2 orf19.7803|orf19.7804|IPF27143.1|IPF17362.2|Contig4-1796_0002|Contig4-2440_0001|orf6.2906|orf6.629|orf6.2907|CA1415|orf19.170|CA1416|DBP2.exon1|DBP2.exon2|IPF18681.1 Predicted ORF in Assemblies 19, 20 and 21; flucytosine induced; downregulated in core stress response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 564976 565425 - ntar_1217 564976 565425 1 565425 564976 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 565458 568840 + orf19.169 565458 568840 1 565458 568840 566055 568721 CHO2 orf19.7802|IPF19595.2|IPF19594.1|Contig4-2571_0007|orf6.2905|orf6.628|CA1414|CaO19.169 Putative phosphatidyl-ethanolamine N-methyltransferase; fungal-specific (no human or murine homolog); amphotericin B repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 568728 569778 - orf19.168 568728 569778 1 569778 568728 569697 568822 orf19.7801|IPF14111.3|IPF16693.2|Contig4-2571_0006|orf6.1406|orf6.2904|CA1413|MTR3|CaO19.168 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 569940 573138 - orf19.166 569940 573138 1 573138 569940 573050 570078 ASG1 orf19.7800|IPF14113.2|IPF29937.1|IPF18682.2|Contig4-2571_0004|orf6.1405|orf6.2902|orf6.2903|CA0465|CA6313|orf19.167|IPF14113.5f|IPF14113 Predicted zinc-finger protein of unknown function; has similarity to S. cerevisiae Asg1p, which is a proposed transcription factor of the Gal4p family [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 574357 576156 + ntar_1218 574357 576156 1 574357 576156 574972 575286 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 574513 576129 - orf19.164 574513 576129 1 576129 574513 575931 574726 orf19.7798|IPF14116.2|IPF10909.2|Contig4-2571_0002|orf6.1403|orf6.157|CA0464|CaO19.164|IPF14116 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 576925 578165 + orf19.163 576925 578165 1 576925 578165 576987 577937 orf19.7797|orf19.10333|IPF18979.2|IPF10907.2|IPF24497.1|IPF18946.1|orf6.156|orf6.1523|CA0463|CA0536|orf19.2815|IPF18979.5eoc|IPF18979|IPF18979.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 577998 581285 - orf19.2818 577998 581285 1 581285 577998 581285 578073 orf19.10336|IPF24524.1|IPF19698.1|Contig4-2405_0001|Contig4-2405_0002|orf6.1526|CA0537|CaO19.10336|PRP16|CaO19.2818 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chrR 581281 582010 + orf19.2819 581281 582010 1 581281 582010 581337 581990 orf19.10337|IPF24499.1|IPF10901.2|Contig4-2405_0004|orf6.1527|CA0538|CaO19.2819|CaO19.10337|IPF10901 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 581772 583875 - orf19.2820 581772 583875 1 583875 581772 583786 582056 orf19.10338|IPF24485.1|IPF10900.2|Contig4-2405_0005|Contig4-2405_0006|orf6.1528|orf6.2208|CA0539|CaO19.2820|NUP57 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 583923 585070 - orf19.2821 583923 585070 1 585070 583923 584978 584451 orf19.10339|IPF24508.1|IPF10896.2|Contig4-2405_0008|orf6.1529|orf6.2209|CA0540|CaO19.2821|CaO19.10339|IPF10896 Predicted ORF in Assemblies 19, 20 and 21; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 585228 586203 - orf19.2822 585228 586203 1 586203 585228 586101 585256 orf19.10340|IPF10894.2|IPF10895.3|orf6.1530|orf6.2210|CA0970|CaO19.2822|COG2|IPF10894 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 599026 602257 + orf19.2823 599026 602257 1 599026 602257 600293 602095 RFG1 orf19.10341|orf6.1681|IPF14334.2|orf6.1166|orf6.1680|ROX1|CA6270|CA0346|orf19.2824|RFG1.5f Transcriptional regulator of filamentous growth and hyphal genes; acts in Tup1p-dependent and -independent pathways; binds DNA; has HMG domain; not transcriptionally regulated by oxygen or serum; not responsible for hypoxic repression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 603357 603724 + ntar_1219 603357 603724 1 603357 603724 603449 603598 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 608393 608708 + ntar_1220 608393 608708 1 608393 608708 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 608848 610601 - orf19.2825 608848 610601 1 610601 608848 610363 609134 orf19.10342|IPF10974.2|IPF16047.1|Contig4-1745_0001|Contig4-1745_0002|Contig4-2642_0009|orf6.1251|orf6.1898|CA0381|CaO19.2825|IPF16047 Predicted ORF in Assemblies 19, 20 and 21; a-specific transcription [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 610954 612397 + ntar_1222 610954 612397 1 610954 612397 610954 611190 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 611059 611518 - ntar_1221 611059 611518 1 611518 611059 611512 611327 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 611877 612047 - ntar_1223 611877 612047 1 612047 611877 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 612406 612855 - ntar_1224 612406 612855 1 612855 612406 612565 612407 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 612995 614742 - orf19.2826 612995 614742 1 614742 612995 614526 613126 orf19.10344|IPF24489.1|IPF10967.2|Contig4-2642_0003|orf6.1900|CA0769|CaO19.10344|CaO19.2826|IPF10967 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 613391 613653 + ntar_1225 613391 613653 1 613391 613653 613418 613615 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 615667 618515 + orf19.2827 615667 618515 1 615667 618515 615887 618253 orf19.10345|IPF10963.2|IPF28963.1|Contig4-1774_0003|orf6.1901|CA0770|CaO19.10345|TID3|CaO19.2827|IPF10963 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chrR 618561 619846 + orf19.2828 618561 619846 1 618561 619846 618846 619694 orf19.10346|IPF24500.1|IPF16925.2|Contig4-1817_0001|orf6.4489|CA2543|CaO19.2828|ALF1|IPF16925 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 619857 620546 + orf19.2829 619857 620546 1 619857 620546 620009 620392 orf19.10347|IPF24510.1|IPF16924.2|Contig4-1817_0003|orf6.4490|CA2544|CaO19.10347|CaO19.2829|IPF16924 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 620741 622595 + orf19.2830 620741 622595 1 620741 622595 620821 622470 RRP9 orf19.10348|IPF24486.1|IPF15036.2|Contig4-2090_0002|orf6.4491|CA2545|CaO19.10348|CaO19.2830 Predicted ORF in Assemblies 19, 20 and 21; mutation confers resistance to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); physically interacts with TAP-tagged Nop1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 622318 623661 - orf19.2831 622318 623661 1 623661 622318 623532 622663 RPC31 orf19.10349|IPF14908.2|IPF15034.1|Contig4-2090_0003|orf6.4492|orf6.759|CA2546|CA0283|CaO19.10349|CaO19.2831|CA0024|RPC31.5eoc|IPF14908.1|CA0174|MDN1|IPF11182.3eoc|IPF11182.2 Predicted ORF in Assemblies 19, 20 and 21; repressed by nitric oxide; induced during infection of murine kidney, compared to growth in vitro; has murine homolog [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 623872 624686 - ntar_1226 623872 624686 1 624686 623872 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 626345 626738 + ntar_1227 626345 626738 1 626345 626738 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 626600 626853 - ntar_1228 626600 626853 1 626853 626600 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 627224 629598 + orf19.2832 627224 629598 1 627224 629598 627521 629500 INN1 orf19.10350|IPF24482.1|IPF14911.2|Contig4-2142_0001|Contig4-2770_0015|orf6.4493|CA2547|CaO19.2832|IPF14911 Protein with similarity to S. cerevisiae Inn1p, which is an essential protein of the contractile actomyosin ring required for ingression of the plasma membrane into the bud neck during cytokinesis; contains a C2 membrane targeting domain [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 629548 630901 - orf19.2833 629548 630901 1 630901 629548 630659 630066 PGA34 orf19.10351|IPF24503.1|IPF9101.2|Contig4-2770_0002|orf6.4494|CA2548|CaO19.10351|CaO19.2833|IPF9101 Putative GPI-anchored protein of unknown function; transcription is repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 632514 632969 + ntar_1229 632514 632969 1 632514 632969 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 632870 634581 - orf19.2834 632870 634581 1 634581 632870 634439 632997 RPD3 orf19.10352|IPF24488.1|IPF9100.2|Contig4-2770_0006|orf6.4495|CA2549|CaO19.10352|RPD32|CaO19.2834|RPD31 Histone deacetylase; regulates frequency of white-to-opaque and opaque-to-white switching; greater expression in white cells than opaque cells; has conserved deacetylation motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 633246 633408 + ntar_1230 633246 633408 1 633246 633408 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 633513 634169 + ntar_1231 633513 634169 1 633513 634169 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 634761 636194 - orf19.2835 634761 636194 1 636194 634761 636143 634977 orf19.10353|IPF24490.1|IPF9099.2|Contig4-2770_0009|orf6.4496|CA2550|AOS1|CaO19.2835|CaO19.10353|IPF9099 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 636873 637364 + orf19.2836 636873 637364 1 636873 637364 636873 637364 orf19.10354|IPF24505.1|IPF9098.1|Contig4-2770_0010|orf6.4497|CA2551|CaO19.10354|CaO19.2836|IPF9098 Protein with similarity to carbonic anhydrases; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 637192 638698 - orf19.2837 637192 638698 1 638698 637192 638526 637555 ALG5 orf19.10355|IPF24493.1|IPF9097.2|Contig4-2770_0011|orf6.4498|CA2552|CaO19.2837|CaO19.10355 Putative glucosyltransferase involved in cell wall mannan biosynthesis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 638896 641346 - orf19.2838 638896 641346 1 641346 638896 641346 638896 orf19.10356|IPF24480.1|IPF9096.1|Contig4-2770_0012|orf6.4499|CA2553|CaO19.2838|CaO19.10356|IPF9096 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to amphotericin B [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chrR 638913 640340 + ntar_1232 638913 640340 1 638913 640340 639807 639992 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 641823 643557 + orf19.2839 641823 643557 1 641823 643557 641823 643490 CIRT4B orf19.10357|IPF15077.2|IPF9095.1|Contig4-2083_0001|Contig4-2770_0014|orf6.1773|orf6.4500|CA2554|CTN3|CaO19.2839|Cirt4|CA0691|Cirt4a|IPF15077.1|Cirt4b Decreased transcription is observed in an azole-resistant strain that overexpresses CDR1 and CDR2 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chrR 644253 646239 + orf19.2841 644253 646239 1 644253 646239 644428 646110 PGM2 orf19.10359|IPF15073.2|IPF28967.1|Contig4-2083_0003|orf6.1775|CA0692|CaO19.2841 Protein not essential for viability; similar to S. cerevisiae Pgm2p, which is phosphoglucomutase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 645470 645953 - ntar_1233 645470 645953 1 645953 645470 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 646107 646265 - ntar_1234 646107 646265 1 646265 646107 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 646604 647264 + ntar_1235 646604 647264 1 646604 647264 646680 647060 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 647252 649813 - orf19.2842 647252 649813 1 649813 647252 649544 647412 GZF3 orf19.10361|IPF18898.1|IPF13959.2|Contig4-2206_0005|Contig4-2206_0007|orf6.1777|orf6.4936|CA2865|DAL80|CaO19.2842 Predicted ORF in Assemblies 19, 20 and 21; oxidative stress-induced via Cap1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 650185 650567 - ntar_1236 650185 650567 1 650567 650185 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 650673 650826 - ntar_1237 650673 650826 1 650826 650673 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 653726 654778 + orf19.2843 653726 654778 1 653726 654778 653856 654452 RHO1 orf19.10362|IPF24501.1|IPF11690.2|Contig4-2293_0002|Contig4-3058_0012|orf6.4937|CA2866|CaO19.2843|CaO19.10362 Small GTPase of Rho family; regulates beta-1,3-glucan synthesis activity and binds Gsc1p; essential; expected to be geranylgeranylated by geranylgeranyltransferase type I [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 655008 657778 + orf19.2844 655008 657778 1 655008 657778 655168 657654 orf19.10363|IPF24477.1|IPF11688.2|Contig4-2293_0001|orf6.4938|CA2867|CaO19.2844|APL4|CaO19.10363|IPF11688 Predicted ORF in Assemblies 19, 20 and 21; induced in core caspofungin response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 656851 657398 - ntar_1238 656851 657398 1 657398 656851 657374 656916 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 657825 658947 + orf19.2846 657825 658947 1 657825 658947 658232 658645 orf19.10365|IPF24513.1|IPF20118.1|Contig4-2393_0002|orf6.4940|CA2868|CaO19.10365|CaO19.2846|IPF20118 Predicted ORF in Assemblies 19, 20 and 21; induced in core caspofungin response; transcription regulated upon yeast-hyphal switch [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 658330 658509 - ntar_1239 658330 658509 1 658509 658330 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 658745 660716 - orf19.2847 658745 660716 1 660716 658745 660647 658860 orf19.10366|IPF17922.3|IPF15457.2|Contig4-2393_0003|orf6.186|orf6.4941|CA2869|RPC82|CaO19.2847 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 661108 661899 + orf19.2847.1 661108 661899 1 661108 661899 661446 661631 IPF17923.2|IPF17924.1|Contig4-2393_0004|CA2870|OPT2.53f Pseudogene; formerly an ORF Predicted by Annotation Working Group that was subsequently removed from Assembly 20 [label_first_exon=CGD label_last_exon=CGD orf_changed=true scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 664536 667049 + orf19.2848 664536 667049 1 664536 667049 664679 666964 orf19.10367|IPF16560.2|IPF10707.2|orf6.4942|orf6.525|CA2872|CaO19.2848|APG13 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 667589 668752 - orf19.2849 667589 668752 1 668752 667589 668605 667784 AQY1 orf19.10368|IPF24496.1|IPF10705.1|Contig4-2389_0006|orf6.4943|CA2873|CaO19.2849 Aquaporin water channel; mutant has increased resistance to osmotic shock; required for wild-type tolerance of freezing; not required for virulence in a mouse model of systemic infection; flucytosine repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 672862 678861 + orf19.2850 672862 678861 1 672862 678861 672973 678729 orf19.10369|IPF17450.3|IPF10699.3|Contig4-2389_0003|orf6.1274|orf6.3280|orf6.4944|CA0392|CaO19.2850|IPF17450|CA1671|IPF11391|IPF11391.2 Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide in yhb1 mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 678731 680154 - orf19.2851 678731 680154 1 680154 678731 679969 678890 orf19.10370|IPF24491.1|IPF11392.2|Contig4-2764_0012|orf6.3279|CA1670|CaO19.2851|CaO19.10370|IPF11392 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 680527 681246 - orf19.2852 680527 681246 1 681246 680527 681188 680607 orf19.10371|IPF24502.1|IPF11393.2|Contig4-2764_0007|orf6.3278|CA1669|MRP21|CaO19.10371|CaO19.2852|IPF11393 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 681416 682646 + orf19.2853 681416 682646 1 681416 682646 681673 682536 orf19.10372|IPF24495.1|IPF11396.1|Contig4-2764_0006|orf6.3277|CA1668|CaO19.2853|CaO19.10372|IPF11396 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 682526 685278 - orf19.2857 682526 685278 1 685278 682526 685210 682679 orf19.10376|IPF24479.1|IPF11402.2|Contig4-2764_0003|Contig4-2764_0004|orf6.3273|CA1667|SSL2|CaO19.10376|CaO19.2857 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 685457 686858 - orf19.2859 685457 686858 1 686858 685457 686858 685572 SRP40 orf19.10377|IPF15769.2|IPF19740.1|Contig4-2764_0002|orf6.3271|orf6.730|CA1666|CaO19.2859 Predicted ORF in Assemblies 19, 20 and 21; macrophage/pseudohyphal-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 686889 688194 - orf19.2862 686889 688194 1 688194 686889 688029 687001 RIB1 orf19.10380|IPF15765.1|IPF18635.1|Contig4-2764_0001|orf6.3268|orf6.733|CA1665|CaO19.2862 Putative GTP cyclohydrolase II; enzyme of riboflavin biosynthesis; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 689539 690300 - orf19.2863 689539 690300 1 690300 689539 690263 689763 orf19.10381|IPF19166.2|IPF7313.2|Contig4-2091_0004|orf6.3267|orf6.734|CaO19.2863 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 690340 691106 - orf19.2863.1 690340 691106 2 691106|690910 690970|690340 691067 690460 IPF24509.1|IPF7312.2|Contig4-2091_0003|CA1664|ERV1.3f|ERV1.3 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 691220 692174 - orf19.2426 691220 692174 1 692174 691220 692173 691391 orf19.9964|orf19.10382|IPF24925.1|IPF17722.2|IPF24494.1|IPF7309.1|Contig4-2091_0001|orf6.5167|orf6.3266|CA1663|orf19.2864|CaO19.9964|CaO19.2426 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 692489 693534 - orf19.2864.1 692489 693534 2 693534|693134 693486|692489 693534 692734 RPL28 IPF24932.1|IPF29116.1|IPF7308.2|Contig4-1322_0001|CA6203|orf19.2425.2 Putative ribosomal protein; Plc1p-regulated; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGD label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 692539 692684 + ntar_1240 692539 692684 1 692539 692684 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 693813 695421 - orf19.2425 693813 695421 1 695421 693813 695366 693876 HGT18 orf19.9963|orf19.10383|IPF24913.1|IPF7306.2|IPF24492.1|IPF18637.1|Contig4-1322_0003|Contig4-2445_0001|orf6.5168|orf6.3265|CA3040|orf19.2865|CaO19.2425|CaO19.9963|IPF7306 Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; expressed in rich medium with 2% glucose [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 694026 694350 + ntar_1241 694026 694350 1 694026 694350 694171 694350 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 695543 697640 - orf19.2423 695543 697640 2 697640|697345 697445|695543 697519 695735 ZCF11 orf19.9961|YBR239c|IPF24910.1|IPF7303.2|Contig4-2445_0002|orf6.5170|CA3041|IPF7303 Putative DNA-binding transcription factor with a zinc cluster domain, required for wild-type filamentous growth; mRNA binds to She3p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 698377 699635 + orf19.2422 698377 699635 1 698377 699635 698444 699553 ARC1 orf19.9960|IPF24918.1|IPF7302.2|Contig4-2445_0005|orf6.5171|CA3042|CaO19.9960|CaO19.2422 Predicted ORF in Assemblies 19, 20 and 21; macrophage/pseudohyphal-repressed; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 699778 701113 + orf19.2419 699778 701113 1 699778 701113 699798 700979 orf19.9957|IPF24917.1|IPF7299.2|Contig4-2445_0006|Contig4-2529_0007|orf6.5174|CA3043|DOM34|CaO19.2419|CaO19.9957 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 700878 701613 - orf19.2418 700878 701613 1 701613 700878 701577 701002 orf19.9956|IPF24930.1|IPF7298.2|Contig4-2445_0007|Contig4-2529_0006|orf6.5175|CA3044|CaO19.2418|CaO19.9956|IPF7298 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 701679 702370 - orf19.2416.1 701679 702370 2 702370|702259 702327|701679 702329 701831 MLC1 IPF24934.1|IPF7297.1|Contig4-2529_0004|CA3045|IPF7297.3 Protein with microtubule-dependent localization to the Spitzenkorper, also localizes to cytokinetic ring in hyphae; cell-cycle dependent localization to bud tip (polarisome) and bud neck in yeast and pseudohyphal cells [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 702805 706204 + orf19.2417 702805 706204 1 702805 706204 702960 706181 SMC5 orf19.9955|IPF24940.1|IPF7295.2|Contig4-2529_0002|Contig4-2529_0003|orf6.5176|YOL034W|CA3046|CaO19.9955|CaO19.2417|IPF7295 Predicted ORF in Assemblies 19, 20 and 21; similar to S. cerevisiae Yol034wp, which is involved in DNA repair; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 706356 707979 + orf19.2415 706356 707979 1 706356 707979 706386 707915 orf19.9953|IPF7294.2|IPF14995.2|Contig4-2529_0001|orf6.39|orf6.5178|CA0004|CaO19.2415|MSE1|MSE2|CA3047 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 708028 709186 + orf19.2414 708028 709186 1 708028 709186 708148 709116 orf19.9952|IPF24922.1|IPF14994.2|Contig4-2124_0007|orf6.40|orf6.5179|CA0005|CaO19.2414|IPF14994 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 709350 710205 + orf19.2412 709350 710205 1 709350 710205 709563 709997 orf19.9950|IPF14991.1|IPF29117.1|Contig4-2124_0004|orf6.5181|CA3048|CaO19.9950|VPS55|CaO19.2412|IPF14991 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 710140 711041 - orf19.2411 710140 711041 1 711041 710140 710988 710188 orf19.9949|IPF14990.2|IPF29114.1|Contig4-2124_0003|orf6.5182|CA3049|CaO19.2411|IPF14990 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 711265 714211 + orf19.2410 711265 714211 1 711265 714211 711423 714110 SYS3 orf19.9948|IPF13042|IPF13042.2|IPF29110.1|Contig4-2486_0006|orf6.5183|CA3050|IMH1|CaO19.2410 Protein similar to S. cerevisiae Sys3p; putative role in endosome-Golgi vesicle docking; upregulated in biofilm; induced upon adherence to polystyrene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 714227 715156 + orf19.2408 714227 715156 1 714227 715156 714287 715114 orf19.9946|IPF24924.1|IPF13043.2|Contig4-2486_0005|orf6.5185|CA3051|CaO19.9946|CaO19.2408|IPF13043 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 715340 717200 + orf19.2407 715340 717200 1 715340 717200 715388 717124 DPS1-1 orf19.9945|IPF13045.2|IPF29111.1|DPS1|Contig4-2486_0004|orf6.5186|CA3052|CaO19.2407|CaO19.9945 Putative tRNA-Asp synthetase; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 717295 718701 + orf19.2406 717295 718701 1 717295 718701 717483 718604 orf19.9944|IPF13046.2|IPF19191.2|Contig4-2486_0003|orf6.5187|orf6.667|CA3053|GTR2|CaO19.2406 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 718813 719056 - snrnau1 718813 719056 1 719056 718813 718997 718863 Highly conserved U1 small nuclear RNA involved in splicing; ortholog of S. cerevisiae SNR19 [label_first_exon=CGD label_last_exon=CGD orf_changed=true scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 719160 721600 - orf19.2404 719160 721600 1 721600 719160 721531 719192 orf19.9943|IPF24915.1|IPF14929.3|Contig4-2486_0001|orf6.5188|orf6.564|orf6.665|CA0148|POP1|CaO19.2404|IPF14929.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 721660 722493 - orf19.2402 721660 722493 1 722493 721660 722431 721751 SSU72 orf19.9939|IPF14932.1|IPF29115.1|Contig4-1536_0001|orf6.562|CA0114|CaO19.2402 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 722552 724005 - orf19.2401 722552 724005 1 724005 722552 723935 722595 orf19.9938|IPF14934.1|IPF29112.1|Contig4-1536_0003|Contig4-1537_0003|orf6.561|CA0113|CaO19.2401|ATG4|AUT2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 722682 722909 + ntar_1242 722682 722909 1 722682 722909 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 724172 726432 + orf19.2400 724172 726432 1 724172 726432 724234 726351 orf19.9937|IPF24907.1|IPF15232.2|Contig4-1537_0001|Contig4-2658_0009|orf6.3673|orf6.559|orf6.560|CA1960|CaO19.2400|IPF15232|IPF15232.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 726361 728290 - orf19.2399 726361 728290 1 728290 726361 728183 726438 orf19.9935|orf6.229|IPF14284.2|IPF15229.2|Contig4-2658_0008|orf6.3674|CA1961|CaO19.2399|JJJ1|IPF14284 Putative transcription factor with zinc finger DNA-binding motif; similar to bacterial DnaJ; transcriptionally regulated by iron; expression greater in low iron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 728411 729874 - orf19.2398 728411 729874 1 729874 728411 729390 728527 orf19.9934|IPF15228.3|IPF14285.2|Contig4-2658_0006|orf6.3675|CA1962|CaO19.2398|CaO19.9934|IPF14285 Predicted ORF in Assemblies 19, 20 and 21; possible increased transcription in an azole-resistant strain that overexpresses CDR1 and CDR2; possibly transcriptionally regulated by Tac1p; induced by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 730036 730625 + ntar_1243 730036 730625 1 730036 730625 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 731627 733082 + orf19.2397.3 731627 733082 2 731627|732117 732051|733082 731817 732898 IPF16843.2|IPF29123.1|Contig4-2658_0002|Contig4-2658_0003|orf19.2397.2|CA0026|IPF16843 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 734289 736955 + orf19.2397 734289 736955 1 734289 736955 734584 736089 orf19.9933|IPF24912.1|IPF14040.2|orf6.3676|CA1963|CaO19.2397|VHT1|CaO19.9933|IPF14040 Predicted membrane transporter, member of the anion:cation symporter (ACS) family, major facilitator superfamily (MFS); amphotericin B, caspofungin repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 737000 738432 + orf19.2396 737000 738432 1 737000 738432 737211 738287 IFR2 orf19.9932|IPF24919.1|IPF14036.2|Contig4-2106_0003|orf6.3677|CA1964|FZD3|CaO19.2396|CaO19.9932 Increased transcription is observed upon benomyl treatment; transcription is upregulated in response to treatment with ciclopirox olamine, alpha pheromone; regulated by oxidative stress (via Cap1p) and osmotic stress (via Hog1p) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 738489 740051 - orf19.2395 738489 740051 1 740051 738489 740051 738489 IME2 orf19.9931|IPF24911.1|IPF14035.2|Contig4-2106_0002|orf6.3678|CA1965|CaO19.9931|CaO19.2395|IPF14035 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to amphotericin B [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 740777 741862 - orf19.2394 740777 741862 1 741862 740777 741862 740777 orf19.9930|IPF18548.2|IPF11494.2|Contig4-2991_0002|orf6.3679|orf6.3854|CA1966|FZD1|CaO19.2394|IFR4 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 742180 743855 - orf19.2393 742180 743855 3 743855|743077|742937 743136|743040|742180 743782 742231 orf19.9929|IPF11493.2|IPF18580.2|Contig4-2991_0004|orf6.3855|CA2094|CaO19.9929|CaO19.2393|IPF11493 Putative transcription factor with zinc finger DNA-binding motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 743132 743782 - orf19.2392 743132 743782 1 743782 743132 743782 743132 orf19.9928|IPF11492|IPF24928.1|IPF11492.2|Contig4-2991_0005|orf6.3856|CA2095|CaO19.9928|CaO19.2392 Protein not essential for viability [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 744004 745268 + orf19.2391 744004 745268 1 744004 745268 744086 745159 orf19.9927|IPF24921.1|IPF11491.2|Contig4-2991_0006|orf6.3857|CA2096|CaO19.2391|CaO19.9927|IPF11491 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 745108 746277 - orf19.2389 745108 746277 1 746277 745108 746253 745189 orf19.9925|IPF24920.1|IPF11489.2|Contig4-2991_0007|orf6.3859|CA2097|CaO19.9925|SLD2|CaO19.2389|IPF11489 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 746404 748244 - orf19.2387 746404 748244 1 748244 746404 748211 746469 orf19.9923|IPF24906.1|IPF11487.2|Contig4-2991_0009|orf6.3861|YER087W|CA2098|CaO19.9923|CaO19.2387|IPF11487 Putative tRNA-Pro synthetase; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 748415 749356 + orf19.2386 748415 749356 1 748415 749356 748452 749195 orf19.9922|IPF24927.1|IPF11484.2|Contig4-2991_0011|orf6.3862|CA2099|CaO19.9922|CaO19.2386|IPF11484 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 749148 750124 - orf19.2385 749148 750124 1 750124 749148 750070 749204 KTI12 orf19.9921|orf6.3863|IPF24923.1|IPF9366.2|Contig4-2991_0012|CA2100|CaO19.2385|CaO19.9921 Protein similar to S. cerevisiae Kti12p, which associates with Elongator complex; has a role in resistance to killer toxin; predicted Kex2p substrate [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 750222 751750 + orf19.2384 750222 751750 1 750222 751750 750309 751415 orf19.9920|IPF24916.1|IPF9364.2|Contig4-2991_0013|orf6.3864|CA2101|CaO19.9920|CaO19.2384|IPF9364 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 751233 753352 - orf19.2383 751233 753352 1 753352 751233 753241 751412 YKU80 orf19.9919|IPF24905.1|IPF9363.2|Contig4-2991_0014|orf6.3865|CA2102|CaO19.2383|CaO19.9919|IPF9363 Protein described as DNA double-strand break repair factor [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 753424 756492 + orf19.2382 753424 756492 1 753424 756492 753493 756414 orf19.9918|IPF9361.2|IPF29109.1|Contig4-2991_0016|orf6.3866|CA2103|ISM1|CaO19.2382 Predicted ORF in Assemblies 19, 20 and 21; similar to isoleucyl-tRNA synthetase; isoleucyl-tRNA synthetase is the target of drugs including the cyclic beta-amino acid icofungipen/PLD-118/BAY-10-8888 and mupirocin [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 756675 757815 + orf19.2381 756675 757815 1 756675 757815 756742 757680 orf19.9917|IPF19939.1|IPF16604.2|Contig4-2991_0017|orf6.1378|orf6.3867|CA2104|CaO19.2381|IPF19939 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 757573 759597 - orf19.2379 757573 759597 2 759597|759406 759489|757573 759538 757726 NOT4 orf19.9915|MOT2|IPF24909.1|IPF9357.2|Contig4-2991_0018|orf6.1380|orf6.3869|CA0449|SIG1|CaO19.2379|MOT2.3f|MOT2.3 Putative E3 ubiquitin-protein ligase; required for maintenance, but not induction, of hyphal development; homozygous null mutant is avirulent in mouse systemic infection despite persistence in host; repressed in rat oral candidiasis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 759746 760160 + orf19.2378 759746 760160 1 759746 760160 759807 760160 orf19.9914|IPF18546.2|IPF9353.1|Contig4-2991_0019|Contig4-2991_0020|orf6.1381|orf6.3870|CA0450|PKR1|CaO19.2378|IPF9353 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chrR 760303 761082 + orf19.2376 760303 761082 1 760303 761082 760303 761082 orf19.9912|IPF24926.1|IPF9352.1|Contig4-2991_0021|orf6.1383|HNT32|CaO19.9912|CaO19.2376 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 762145 764045 + orf19.4384 762145 764045 2 762145|762718 762617|764045 762145 763933 HXT5 orf19.11862|orf19.11864|IPF3282|IPF22904.1|IPF3282.1|IPF3277|Contig4-3077_0025|Contig4-3077_0029|orf6.6321|orf6.6323|CA3914|orf19.4386|HXT10|CA3915|IPF3277.1 Protein described as a sugar transporter; transcription is upregulated in response to treatment with ciclopirox olamine; Snf3p-induced; alkaline downregulated; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGD label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 764391 765545 + orf19.4388 764391 765545 1 764391 765545 764392 765510 orf19.11866|IPF22889.1|IPF3283.2|Contig4-3077_0023|orf6.6319|CA3913|CaO19.11866|TAF3|CaO19.4388|IPF3283 Predicted ORF in Assemblies 19, 20 and 21; has histone fold domain; similar to TAFII47 proteins from S. cerevisiae, Danio rerio, Drosophila melanogaster, human, and mouse [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chrR 765183 765865 - ntar_1244 765183 765865 1 765865 765183 765560 765183 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 767080 769174 + orf19.4390 767080 769174 1 767080 769174 767513 769012 orf19.11868|IPF22884.1|IPF3288.1|Contig4-3077_0020|orf6.6317|CA3912|CaO19.11868|CaO19.4390|IPF3288 Predicted ORF in Assemblies 19, 20 and 21; transcription is repressed in response to alpha pheromone in SpiderM medium; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 770495 772621 + orf19.4391 770495 772621 1 770495 772621 770495 772621 orf19.11869|IPF22868.1|IPF3292.2|Contig4-3077_0016|orf6.6316|CA3911|YFW7|CaO19.4391|CaO19.11869|IPF3292 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chrR 773128 775349 + orf19.4392 773128 775349 1 773128 775349 773160 775046 DEM1 orf19.11870|IPF22875.1|IPF3293.2|Contig4-3077_0014|orf6.6315|CA3910|CaO19.4392|CaO19.11870|IPF3293 Predicted ORF in Assemblies 19, 20 and 21; alpha-factor induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chrR 773529 774153 - ntar_1245 773529 774153 1 774153 773529 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 774252 775317 - ntar_1246 774252 775317 1 775317 774252 774458 774252 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 777788 779491 + orf19.4393 777788 779491 2 777788|778020 777926|779491 777837 779333 CIT1 orf19.11871|orf6.6314|IPF22877.1|IPF28424.1|Contig4-3077_0009|CA3909|CIT1.exon2|IPF3299.1 Protein described as citrate synthase; soluble protein in hyphae; biofilm induced; expression greater in high iron; upregulated upon phagocytosis; Hog1p-downregulated; regulated by Efg1p under yeast-form but not hyphal growth conditions [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 780330 782039 + orf19.4394 780330 782039 1 780330 782039 780330 782039 orf19.11872|IPF22876.1|IPF3301.2|Contig4-3077_0008|orf6.6313|CA3908|CaO19.11872|CaO19.4394|IPF3301 Predicted ORF in Assemblies 19, 20 and 21; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 781841 784048 - orf19.4395 781841 784048 1 784048 781841 783889 782048 orf19.11873|IPF3304.2|IPF19225.2|Contig4-3077_0005|orf6.590|orf6.6312|CA3907|AIP1|CaO19.4395|IPF3304 Predicted ORF in Assemblies 19, 20 and 21; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 784206 786340 + orf19.4396 784206 786340 1 784206 786340 784374 786077 orf19.11874|IPF20149.1|IPF20043.1|Contig4-3077_0003|orf6.589|orf6.6311|CA3906|CaO19.4396|FMP13|IPF20149 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 786481 787557 + orf19.4398 786481 787557 1 786481 787557 786517 787491 orf19.11876|IPF19792.1|IPF16920.3|Contig4-3077_0002|orf6.587|orf6.6309|CA3905|CaO19.4398|IPF19792.5f|IPF19792 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 787639 789070 + orf19.4399 787639 789070 1 787639 789070 787653 789011 orf19.11877|IPF14888.2|IPF28426.1|Contig4-3077_0001|orf6.6308|CA3904|CaO19.11877|CaO19.4399|IPF14888 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 789247 790276 + orf19.4400 789247 790276 1 789247 790276 789310 790125 orf19.11878|IPF22896.1|IPF14890.1|Contig4-1712_0002|orf6.6307|CA3903|CaO19.11878|CaO19.4400|IPF14890 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 790003 791121 - orf19.4401 790003 791121 1 791121 790003 791099 790131 YVH1 orf19.11879|IPF22890.1|IPF14891.2|Contig4-1712_0003|orf6.6306|CA3902|CaO19.4401|CaO19.11879 Putative dual specificity phosphatase (phosphoserine/threonine and phosphotyrosine phosphatase); similar to S. cerevisiae Yvh1p; required for wild-type growth rate and for wild-type virulence in mouse model of systemic infection [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 794436 795215 - orf19.4383 794436 795215 1 795215 794436 795215 794436 orf19.11861|IPF22897.1|IPF3274.1|Contig4-3077_0032|orf6.6324|CA3916|CaO19.4383|HNT31|CaO19.11861|IPF3274 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 795383 796244 - orf19.4382 795383 796244 1 796244 795383 796227 795625 orf19.11860|IPF22902.1|IPF3273.1|Contig4-3077_0034|orf6.6325|CA3917|CaO19.11860|RET3|CaO19.4382|IPF3273 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 796432 799516 - orf19.4381 796432 799516 1 799516 796432 798986 796560 VTC3 orf19.11859|IPF22866.1|IPF3271.2|orf6.6326|VTC2|CA3918|CaO19.4381|CaO19.11859 Putative polyphosphate synthetase; downregulated in core caspofungin response; Hog1p-induced; transcription is opaque-specific; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chrR 799773 800009 + ntar_1247 799773 800009 1 799773 800009 799852 799998 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 800802 801019 + ntar_1248 800802 801019 1 800802 801019 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 801143 803746 - orf19.4380.1 801143 803746 1 803746 801143 803746 801143 Predicted ORF in Assembly 20 and 21 (see Locus History) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chrR 804770 807595 + orf19.4361 804770 807595 1 804770 807595 804770 807595 IFF3 orf19.11839|orf6.2179|IPF20094.1|IPF28444.1|Contig4-2765_0012|orf6.3778|CA2037|CaO19.4361|CaO19.11839 Putative GPI-anchored protein of unknown function [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 807108 807331 - ntar_1249 807108 807331 1 807331 807108 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 807641 809658 - orf19.4362 807641 809658 1 809658 807641 809547 808438 orf19.11840|IPF22888.1|IPF7571.1|Contig4-2883_0014|orf6.3776|CA2036|CaO19.11840|MSP1|CaO19.4362 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 809838 812997 + orf19.4363 809838 812997 1 809838 812997 809883 812957 SGD1 orf19.11841|YLR336C|Contig4-2883_0005|IPF7574.2|IPF28445.1|Contig4-2883_0008|Contig4-2883_0011|orf6.2425|orf6.3775|CA2035|CaO19.4363|CA2034|SGD1.3f|IPF18558.1|SGD1.5f Predicted ORF in Assemblies 19, 20 and 21; downregulated during core stress response; transcription is increased in populations of cells exposed to fluconazole over multiple generations [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chrR 812896 815121 - orf19.4365 812896 815121 1 815121 812896 814756 812990 orf19.11843|IPF22879.1|IPF7575.2|Contig4-2883_0004|orf6.2424|orf6.3773|CA1097|TRM22|CaO19.4365|IPF7575 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chrR 816393 818339 + orf19.4366 816393 818339 1 816393 818339 816393 818339 orf19.11844|IPF18559.2|IPF7578.2|Contig4-2883_0002|orf6.2423|orf6.3772|CA1096|CaO19.4366|YFW8|IPF7578 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 818344 822214 - orf19.4367 818344 822214 1 822214 818344 822147 818425 SMC1 orf19.11845|IPF22919.1|IPF7580.2|Contig4-2883_0001|orf6.2422|CA1095|CaO19.11845|CaO19.4367 Protein described as similar to chromosomal ATPases; RNA abundance regulated by tyrosol and cell density; cell-cycle regulated periodic mRNA expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 823073 825562 + orf19.4368 823073 825562 1 823073 825562 823246 825456 orf19.11846|IPF12369.2|IPF15478.2|Contig4-2011_0002|Contig4-2011_0003|orf6.2254|orf6.2421|CA0998|CaO19.4368|IPF12369 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 825426 829073 - orf19.4369 825426 829073 1 829073 825426 829063 825518 orf19.11847|IPF12368|IPF12368.2|IPF28438.1|Contig4-2011_0004|Contig4-2376_0001|Contig4-2376_0002|Contig4-2376_0003|orf6.2255|CA0999|CaO19.11847|CaO19.4369 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 829292 829868 + ntar_1250 829292 829868 1 829292 829868 829391 829525 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 829349 830901 - orf19.4370 829349 830901 1 830901 829349 830528 829626 orf19.11848|IPF22892.1|IPF9450.2|Contig4-2376_0005|orf6.4535|CA2581|CaO19.4370|IPF9450 Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide; oxidative stress-induced via Cap1p; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 831797 832932 + orf19.4371 831797 832932 1 831797 832932 831860 832831 TAL1 orf19.11849|IPF22891.1|IPF9448.2|Contig4-2376_0009|orf6.4536|CA2582|CaO19.11849|CaO19.4371 Predicted ORF in Assemblies 19, 20 and 21; biofilm induced; oxidative stress-induced via Cap1p; induced by nitric oxide in yhb1 mutant; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 832959 835174 - orf19.4372 832959 835174 1 835174 832959 834547 833216 orf19.11850|IPF22878.1|IPF9445.2|Contig4-2849_0001|Contig4-2849_0005|orf6.4537|CA2583|CaO19.11850|CaO19.4372|IPF9445 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chrR 835432 836004 + ntar_1251 835432 836004 1 835432 836004 835629 835847 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 835722 836670 - orf19.4373 835722 836670 1 836670 835722 836568 836038 orf19.11851|orf6.4538|IPF22903.1|IPF9440.1|Contig4-2849_0008|CA2584|FMN1|CaO19.11851|CaO19.4373|IPF9440 Protein similar to S. cerevisiae Fmn1p, which is riboflavin kinase; predicted Kex2p substrate [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 836746 838099 - orf19.4374 836746 838099 1 838099 836746 838038 836857 PRP42 orf19.11852|IPF22887.1|IPF9438.2|Contig4-2849_0010|orf6.4539|CA2585|CaO19.11852|CaO19.4374|IPF9438 Putative component of the U1 snRNP, involved in splicing; ortholog of S. cerevisiae PRP42; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 839046 840011 + orf19.4375 839046 840011 1 839046 840011 839137 839925 orf19.11853|IPF22895.1|IPF9435.1|Contig4-2849_0013|orf6.4540|CA2586|CaO19.4375|CaO19.11853|IPF9435 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 839897 840886 - orf19.4375.1 839897 840886 2 840886|840471 840808|839897 840810 840283 RPS30 IPF22874.1|IPF15100.2|Contig4-2849_0014|CA2587|RPS30.3 ORF Predicted by Annotation Working Group; putative 40S ribosomal protein S30; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 841184 842107 - orf19.4376 841184 842107 1 842107 841184 841970 841233 orf19.11854|IPF22898.1|IPF15098.2|Contig4-2849_0015|orf6.4541|CA2588|CaO19.11854|CaO19.4376|IPF15098 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 841193 841542 + ntar_1252 841193 841542 1 841193 841542 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 843689 844774 - orf19.4377 843689 844774 1 844774 843689 844400 844008 KRE1 orf19.11855|IPF22909.1|IPF13702.2|Contig4-2849_0017|orf6.4542|CA2589|CaO19.11855|CaO19.4377 Predicted GPI-anchor, role in 1,6-beta-D-glucan biosynthesis; production in S. cerevisiae increases glucan content and complements killer toxin sensitivity of kre1 mutant; possible N-linked glycosylation at Asn109; caspofungin induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 847747 848937 - orf19.4378 847747 848937 2 848937|848736 848812|847747 848828 847833 orf19.11828|orf19.11856|IPF22894.1|IPF13700.2|IPF22893.1|IPF12918.1|Contig4-2577_0002|Contig4-2849_0022|orf6.2806|orf6.4543|CA1348|CA2590|orf19.4350|CaO19.11856|CaO19.4378|PPH32.3f|PPH3.3b Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 849327 852183 + orf19.4379 849327 852183 1 849327 852183 849450 852053 PRP13 orf19.11829|orf19.11857|IPF15868.3|IPF12922.2|IPF22865.1|IPF28423.1|Contig4-2577_0006|Contig4-2720_0005|Contig4-2720_0006|orf6.2807|orf6.4544|orf6.6327|orf6.352|orf6.575|CA1349|orf19.4351|PRP12|CaO19.4379|PRP122 Predicted ORF in Assemblies 19, 20 and 21; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chrR 852053 853605 - orf19.4353 852053 853605 1 853605 852053 853582 852107 ULP2 orf19.11831|IPF19593.1|IPF19592.1|Contig4-2720_0003|orf6.2809|orf6.576|CA0120|CaO19.4353|ULP1|IPF19592|IPF19593 Putative SUMO deconjugation enzyme that removes the small ubiquitin-like modifier (SUMO) from proteins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 853888 856787 - orf19.4354 853888 856787 1 856787 853888 856674 853963 MCM2 orf19.11832|IPF17769.3|IPF15306.2|Contig4-2720_0001|orf6.2810|orf6.577|CA1350|CaO19.4354 Phosphorylated protein of unknown function; transcription is periodic with a peak at M/G1 phase of the cell cycle; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 857847 858891 - orf19.4355 857847 858891 1 858891 857847 858505 857993 orf19.11833|orf6.2811|orf6.3783|CA2041|CaO19.4355|IPF12944|IPF12944.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 860471 862707 + orf19.4356 860471 862707 1 860471 862707 860668 862611 HGT3 orf19.11834|YDL199C|IPF22873.1|IPF12946.2|Contig4-2535_0003|orf6.3782|CA2040|CaO19.4356|CaO19.11834|IPF12946 Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments, extended C terminus; expressed in rich medium with 2% glucose [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 862678 864462 - orf19.4357 862678 864462 1 864462 862678 864429 862765 orf19.11835|IPF12947.2|IPF17511.3|Contig4-2535_0002|orf6.252|orf6.3781|CA2039|CaO19.4357|IPF12947 Putative protein of unknown function; has similarity to S. cerevisiae Mgr3p, which is a subunit of the i-AAA protease supercomplex that degrades misfolded mitochondrial proteins; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 864646 865346 + orf19.4358 864646 865346 1 864646 865346 864755 865057 orf19.11836|IPF17510.1|IPF12948.1|Contig4-2535_0001|orf6.253|orf6.3780|CA2038|CaO19.4358|IPF17510 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 866462 869287 + orf19.465 866462 869287 1 866462 869287 866462 869287 IFF9 orf19.8096|orf6.2179|IPF19893.2|IPF29820.1|Contig4-2765_0012|Contig4-2883_0016|orf6.353|CaO19.465 Transcriptionally regulated by iron; expression greater in low iron; similar to GPI-linked cell-wall proteins; similar to Hyr1p [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 877809 880666 + orf19.467 877809 880666 1 877809 880666 878587 880515 orf19.8098|IPF26770.1|IPF10055.2|Contig4-2397_0002|Contig4-2397_0004|orf6.3214|CA1624|CaO19.8098|CaO19.467|IPF10055 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 882507 882664 + ntar_1253 882507 882664 1 882507 882664 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 882509 882783 - ntar_1254 882509 882783 1 882783 882509 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 883210 883518 + ntar_1255 883210 883518 1 883210 883518 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 883366 883950 - ntar_1256 883366 883950 1 883950 883366 883950 883453 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 883885 885953 + orf19.469 883885 885953 1 883885 885953 884043 885812 HST7 orf19.8100|STE7|IPF26774.1|IPF10048.2|Contig4-3015_0018|orf6.3212|CA1623|CaO19.8100|CaO19.469 MAP kinase kinase, involved in signal transduction pathways for mating and hyphal growth; phosphorylates Cek1p; not required for wild-type virulence in mouse systemic infection; functional homolog of S. cerevisiae Ste7p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 885863 888475 - orf19.470 885863 888475 1 888475 885863 888243 885991 orf19.8101|IPF11135.3|IPF10045.3|Contig4-2684_0007|orf6.2281|orf6.3211|CA1622|TAF12|CaO19.470|IPF10045|IPF10045.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 888752 891171 - orf19.473 888752 891171 1 891171 888752 890929 888821 TPO4 orf19.8104|IPF26767.1|IPF11142.2|Contig4-2684_0006|orf6.2283|CA1016|CaO19.8104|CaO19.473|IPF11142 Putative sperimidine transporter; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 892669 894283 - orf19.474 892669 894283 1 894283 892669 894237 892936 orf19.8105|IPF11144.1|IPF29797.1|Contig4-2241_0003|orf6.2284|CA1017|CaO19.8105|CaO19.474|IPF11144 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 894672 895949 + orf19.475 894672 895949 1 894672 895949 894751 895851 orf19.8106|orf19.8107|IPF19567.1|IPF26829.1|IPF26805.1|IPF10696.2|IPF19566.1|orf6.329|orf6.986|orf6.987|CA0052|orf19.476|IPF19567 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 896062 897118 + orf19.477 896062 897118 1 896062 897118 896186 896971 orf19.8108|IPF18205.2|IPF7101.1|Contig4-2441_0004|orf6.7093|orf6.988|CA0253|RRF1|CaO19.477|FIL1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 896935 898859 - orf19.478 896935 898859 1 898859 896935 898747 897050 orf19.8109|IPF7100.2|IPF19077.2|IPF29796.1|Contig4-2441_0006|orf6.7092|orf6.989|CA6316|CA4526|orf19.479|MON1.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 898990 899811 - orf19.479.2 898990 899811 2 899811|899671 899749|898990 899782 899055 IPF26812.1|IPF7098.2|Contig4-2441_0008|CA4525|SEC22 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 900060 901252 + orf19.480 900060 901252 1 900060 901252 900155 900883 orf19.8110|IPF26806.1|IPF7097.2|Contig4-2441_0009|Contig4-2441_0010|orf6.7091|CA4524|CaO19.8110|CaO19.480|IPF7097 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 901072 902795 - orf19.481 901072 902795 1 902795 901072 902746 901304 GCD1 orf19.8111|IPF26786.1|IPF7094.1|Contig4-2441_0012|orf6.7090|CA4523|CaO19.8111|CaO19.481 Putative translation initiation factor; transcription is regulated by Mig1p; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 902965 904535 + orf19.482 902965 904535 1 902965 904535 903069 904355 RPT4 orf19.8112|IPF26793.1|IPF7093.1|Contig4-2779_0010|orf6.7089|CA4522|CaO19.482|CaO19.8112 Predicted ORF in Assemblies 19, 20 and 21; regulated by Gcn2p and Gcn4p; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 904377 905502 - orf19.484 904377 905502 1 905502 904377 905449 904433 MRPL40 orf19.8114|IPF26798.1|IPF7091.1|Contig4-2779_0009|orf6.7087|CA4521|CaO19.8114|CaO19.484 Putative mitochondrial ribosomal protein [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 905639 906523 - orf19.485 905639 906523 2 906523|905809 905901|905639 906468 905772 orf19.8115|IPF26809.1|IPF7089.1|Contig4-2779_0007|orf6.7086|CA4520|CDC31 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 906673 909791 + orf19.486 906673 909791 1 906673 909791 906700 909387 NIP100 orf19.8116|IPF26758.1|IPF7088.2|Contig4-2779_0005|orf6.7085|CA4519|CaO19.8116|CaO19.486|IPF7088 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 909100 910878 - orf19.487 909100 910878 1 910878 909100 910720 909362 SPT14 orf19.8117|IPF26792.1|IPF7087.2|Contig4-2779_0003|orf6.7084|CA4518|CaO19.487|CaO19.8117 Putative DNA-binding transcription factor; predicted role in regulation of biogenesis of the cell wall; upregulated in biofilm [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 911014 913130 - orf19.488 911014 913130 1 913130 911014 912970 911117 MEX67 orf19.8118|IPF26772.1|IPF7086.2|Contig4-2779_0001|orf6.7083|CA4517|CaO19.8118|CaO19.488 Nuclear export protein; has NTF2-like domain; interacts with Mtr2p via the NTF2-like domain [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 913216 914135 - orf19.489 913216 914135 1 914135 913216 913874 913407 DAP1 orf19.8119|IPF26817.1|IPF18207.1|orf6.7082|CA4516|CaO19.8119|CaO19.489|IPF18207 Protein similar to S. cerevisiae Dap1p, which is a protein related to mammalian membrane-associated progesterone receptors involved in response to DNA damage; induced in core stress response; Hog1p regulated; clade-associated expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 914297 915379 + orf19.490 914297 915379 1 914297 915379 914690 915217 orf19.8120|IPF26813.1|IPF16652.2|Contig4-1834_0003|orf6.7081|CA4515|NAT5|CaO19.8120|CaO19.490|IPF16652 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 915178 917522 - orf19.491 915178 917522 1 917522 915178 917420 915399 orf19.8121|IPF26769.1|IPF20016.1|Contig4-2904_0012|orf6.7080|CA4514|SEC63|CaO19.8121|CaO19.491|IPF20016 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 917753 919821 - orf19.492 917753 919821 1 919821 917753 919622 917844 ADE17 orf19.8122|IPF26775.1|IPF14907.2|Contig4-2904_0011|orf6.7079|CA4513|CaO19.492|CaO19.8122 Enzyme of adenine biosynthesis; antigenic in human; soluble protein in hyphae; not induced during GCN response, in contrast to the S. cerevisiae ortholog [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 920311 921068 - orf19.493 920311 921068 1 921068 920311 921025 920411 RPL15A orf19.8123|IPF8963.2|IPF15914.3|RPL15B|Contig4-2904_0008|orf6.269|orf6.7078|CA0042|RPL15|CaO19.493|CA4512 Putative ribosomal protein; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage; transcription is positively regulated by Tbf1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 921771 923728 + orf19.494 921771 923728 1 921771 923728 921819 923564 orf19.8124|IPF8966.2|IPF15912.3|Contig4-2904_0005|orf6.270|orf6.7077|CA4511|CaO19.494|NAF1|IPF8966 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 923540 926371 - orf19.496 923540 926371 1 926371 923540 926371 923600 orf19.8126|IPF26756.1|IPF8970.1|Contig4-2904_0004|orf6.7075|CA4510|MSH1|CaO19.8126|CaO19.496|IPF8970 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 926647 928135 - orf19.497 926647 928135 1 928135 926647 927984 926647 EAF7 orf19.8127|IPF26790.1|IPF8973.2|Contig4-2904_0003|orf6.7074|CA4509|CaO19.497|CaO19.8127|IPF8973 subunit of the NuA4 histone acetyltransferase complex [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 928245 929785 + orf19.498 928245 929785 1 928245 929785 928322 929707 orf19.8128|IPF26789.1|IPF8974.2|Contig4-2904_0001|orf6.7073|CA4508|CaO19.8128|NAM9|CaO19.498 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 929962 930882 + orf19.499 929962 930882 1 929962 930882 929962 930882 orf19.8129|IPF26800.1|IPF20015.1|Contig4-2231_0003|orf6.7072|CA4507|CaO19.8129|CaO19.499|IPF20015 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 930773 932455 - orf19.500 930773 932455 1 932455 930773 932345 930984 orf19.8130|IPF26791.1|IPF15038.2|Contig4-2231_0002|orf6.7071|CA4506|CaO19.500|GCD10|CaO19.8130 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 932579 934543 + orf19.501 932579 934543 1 932579 934543 932645 934501 orf19.8131|IPF26773.1|IPF15042.2|Contig4-2231_0001|Contig4-2663_0006|orf6.7070|CA4505|NOP2|CaO19.501|CaO19.8131 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 934442 936982 - orf19.504 934442 936982 1 936982 934442 936927 934597 orf19.8134|IPF26762.1|IPF10388.2|Contig4-2663_0005|orf6.7067|CA4504|ARP5|CaO19.8134|CaO19.504 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 937161 938982 + orf19.505 937161 938982 1 937161 938982 937213 938850 SRV2 orf19.8135|CAP|CAP1|IPF26777.1|IPF10389.2|Contig4-2663_0003|orf6.7066|CA4503|CaO19.8135|CAP001|CaO19.505 Adenylate cyclase-associated protein that regulates adenylate cyclase activity; required for wild-type germ tube formation and for virulence in mouse systemic infection; mutant defects in filamentous growth are rescued by cAMP or dbcAMP [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 939089 940536 + orf19.506 939089 940536 1 939089 940536 939273 940454 YDJ1 orf19.8136|IPF10391.1|IPF29798.1|Contig4-2663_0001|orf6.7065|CA4502|CaO19.506|IPF10391 Predicted ORF in Assemblies 19, 20 and 21; heavy metal (cadmium) stress-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 940919 942821 - orf19.508 940919 942821 1 942821 940919 942696 941167 QDR1 orf19.8138|IPF16422.2|IPF19400.2|Contig4-2663_0007|orf6.183|orf6.7063|CA4501|CaO19.508 Putative transporter of antibiotic resistance; transcription is regulated by Nrg1p and Tup1p; caspofungin repressed; expression is regulated upon white-opaque switching [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 943899 945401 - orf19.510 943899 945401 1 945401 943899 945401 943908 orf19.8141|IPF11319.2|IPF29794.1|Contig4-3063_0003|Contig4-3063_0005|orf6.7060|CA4500|CaO19.8141|GLB|CaO19.510|IPF11319 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chrR 944409 944600 + ntar_1257 944409 944600 1 944409 944600 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 947327 948357 + orf19.511 947327 948357 1 947327 948357 947461 948189 orf19.8142|IPF26802.1|IPF11316.1|Contig4-3063_0011|orf6.7059|CA4499|CaO19.511|CaO19.8142|IPF11316 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 948190 951555 - orf19.512 948190 951555 1 951555 948190 951493 948365 orf19.8143|IPF11315.2|IPF29817.1|Contig4-3063_0012|Contig4-3063_0014|orf6.6724|orf6.7058|CA4498|CaO19.8143|CaO19.512|IPF11315|CA4229|IPF12480.5|IPF12480.1 Predicted ORF in Assemblies 19, 20 and 21; essential; S. cerevisiae ortholog is essential [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 952043 953515 + orf19.513 952043 953515 1 952043 953515 952043 953515 orf19.8144|IPF26785.1|IPF12481.2|Contig4-3063_0015|orf6.6725|CA4230|CaO19.513|NDT802|CaO19.8144|IPF12481 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 953712 954239 + orf19.514 953712 954239 2 953712|954150 954070|954239 953806 954175 SNP3 orf19.8145|IPF26838.1|IPF12483.2|Contig4-3063_0016|orf6.6726|CA4231 Transcription is regulated by Mig1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 954143 954791 - orf19.515 954143 954791 1 954791 954143 954759 954313 orf19.8146|IPF26823.1|IPF12484.2|Contig4-3063_0017|orf6.6727|CA4232|CaO19.515|CaO19.8146|IPF12484 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 955158 955618 + ntar_1258 955158 955618 1 955158 955618 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 955579 957362 - orf19.516 955579 957362 1 957362 955579 957305 955620 orf19.8147|IPF26776.1|IPF12486.1|Contig4-3063_0018|Contig4-3063_0019|orf6.6728|CA4233|CaO19.516|RFT1|CaO19.8147 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 957538 958179 + orf19.517 957538 958179 1 957538 958179 957652 957969 HAP31 orf19.8148|orf6.6729|IPF26841.1|IPF12488.1|Contig4-3063_0020|CA4234|CaO19.517|CaO19.8148|HAP3 Protein described as a transcription factor that regulates CYC1; transcriptionally regulated by iron; expression greater in high iron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 958485 960716 + orf19.518 958485 960716 1 958485 960716 958491 960632 orf19.8149|IPF26766.1|IPF8167.2|Contig4-3063_0021|orf6.6730|CA4235|NCL1|CaO19.518 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 960524 961483 - orf19.519 960524 961483 1 961483 960524 961300 960713 orf19.8150|IPF8168.2|IPF8166.2|Contig4-3063_0022|orf6.399|orf6.6731|CA4236|CaO19.519|CaO19.8150|IPF8166 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 961848 963171 + orf19.520 961848 963171 1 961848 963171 961925 963124 orf19.8151|IPF8170.2|IPF6375.2|Contig4-3063_0023|orf6.398|orf6.6732|CA4237|CaO19.520|IPF6375 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 963524 966889 + orf19.522 963524 966889 1 963524 966889 963557 966793 orf19.8154|IPF26755.1|IPF8173.2|Contig4-3063_0025|orf6.396|orf6.6734|CA4238|PIM1|CaO19.522 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 966806 968294 - orf19.524 966806 968294 1 968294 966806 968252 966906 orf19.8157|IPF26788.1|IPF8174.2|Contig4-3063_0028|orf6.6736|CA4239|CaO19.8157|MLO2|CaO19.524|IPF8174 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 968511 969238 - orf19.526 968511 969238 1 969238 968511 969176 968697 NHP2 orf19.8159|IPF26815.1|IPF8176.1|Contig4-3063_0030|Contig4-3063_0031|orf6.6738|CA4240|CaO19.8159|CaO19.526 Predicted ORF in Assemblies 19, 20 and 21; macrophage/pseudohyphal-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 969332 970299 + orf19.527 969332 970299 1 969332 970299 969440 970225 orf19.8160|IPF26804.1|IPF8177.1|Contig4-3063_0032|orf6.6739|CA4241|CaO19.527|CaO19.8160|IPF8177 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 970192 973287 - orf19.528 970192 973287 1 973287 970192 973196 970338 orf19.8161|IPF26757.1|IPF15941.2|Contig4-3063_0033|orf6.6740|CA4242|CaO19.528|SEC26|CaO19.8161 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 973558 976282 - orf19.529 973558 976282 1 976282 973558 975997 973610 orf19.8162|IPF26764.1|IPF16491.2|Contig4-3063_0038|orf6.6741|CA4243|CaO19.8162|CaO19.529|IPF16491 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 977057 977393 + orf19.529.1 977057 977393 1 977057 977393 977169 977393 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 977537 978941 + orf19.530 977537 978941 1 977537 978941 977537 978862 orf19.8163|IPF4305|IPF26784.1|IPF4305.2|Contig4-2736_0014|orf6.6742|CA4244|CaO19.530|CaO19.8163 Protein not essential for viability; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 978925 980023 - orf19.532 978925 980023 1 980023 978925 979776 979270 RBR2 orf19.8165|orf6.6744|PGA21|IPF26816.1|IPF4303.2|Contig4-2736_0002|CA4245|CaO19.532|IPF4303 Cell wall protein; expression is repressed by Rim101p; expression is regulated upon white-opaque switching; transcription is repressed in response to alpha pheromone in SpiderM medium; macrophage-induced gene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 979100 979893 + ntar_1259 979100 979893 1 979100 979893 979100 979477 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 980823 981137 + orf19.533 980823 981137 1 980823 981137 980823 981137 orf19.8166|IPF26834.1|IPF29811.1|orf6.448|orf6.6745|CaO19.533 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 981988 982497 - orf19.535 981988 982497 1 982497 981988 982434 982099 RBR1 orf19.8168|orf6.6747|PGA20|orf6.450|IPF4300.3|IPF4299.2|Contig4-2736_0005|Contig4-2736_0006|CA4246|CaO19.535|IPF4299 Glycosylphosphatidylinositol (GPI)-anchored cell wall protein required for filamentous growth at acidic pH; expression is repressed by Rim101p and activated by Nrg1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 984068 986649 - orf19.536 984068 986649 1 986649 984068 986606 984210 orf19.8169|IPF26763.1|IPF4296.2|Contig4-2736_0011|orf6.6748|CA4247|CaO19.8169|TAF5|CaO19.536|TAF90 Putative ortholog of S. cerevisiae TAF5; has a LisH motif; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 986772 987748 - orf19.537 986772 987748 1 987748 986772 987660 986863 orf19.8170|IPF26803.1|IPF4294.2|Contig4-2736_0012|orf6.6749|CA4248|CaO19.8170|CaO19.537|IPF4294 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 987802 988911 + orf19.538 987802 988911 1 987802 988911 987838 988752 orf19.8171|IPF26801.1|IPF4293.2|Contig4-2736_0013|orf6.6750|CA4249|CaO19.538|GPI2|CaO19.8171|IPF4293 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 988673 990542 - orf19.539 988673 990542 1 990542 988673 990430 988901 LAP3 orf19.8172|orf6.6751|IPF26781.1|IPF4292.2|CA4250|CaO19.8172|CaO19.539|IPF4292 Protein described as an aminopeptidase; transcription is positively regulated by Sfu1p; transcription is repressed in response to alpha pheromone in SpiderM medium; clade-associated gene expression; virulence-group-correlated expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 990732 991793 - orf19.540 990732 991793 1 991793 990732 991762 990812 orf19.8173|IPF26799.1|IPF4291.2|orf6.6752|CA4251|PPT2|CaO19.540|CaO19.8173|IPF4291 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 991248 991666 + ntar_1260 991248 991666 1 991248 991666 991252 991386 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 991962 993376 - orf19.541 991962 993376 1 993376 991962 993229 992108 orf19.8174|IPF26796.1|IPF4290.1|Contig4-1913_0001|orf6.6753|CA4252|CaO19.8174|CaO19.541|IPF4290 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 993813 994222 + ntar_1261 993813 994222 1 993813 994222 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 994569 994809 - ntar_1262 994569 994809 1 994809 994569 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 995297 996977 + orf19.542 995297 996977 1 995297 996977 995402 996856 HXK2 orf19.8176|IPF4286.2|IPF29795.1|Contig4-2548_0007|orf6.598|orf6.6754|CA0127|CaO19.542|HXK2.3f Protein described as hexokinase II; antigenic in human; downregulated in the presence of human neutrophils; regulated by Efg1p; fluconazole-induced; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 997068 997573 - ntar_1263 997068 997573 1 997573 997068 997418 997143 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 997128 997613 + orf19.542.2 997128 997613 1 997128 997613 997186 997575 IPF4284.2|IPF18234.1|Contig4-2548_0005|orf6.597|CA4254|IPF18234.3f|CA0126|IPF4284|IPF18234.3 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 997714 999429 + orf19.543 997714 999429 1 997714 999429 997835 999223 FUM11 orf19.8178|orf6.6755|IPF19222.2|IPF4283.2|Contig4-2548_0004|orf6.596|CA4255|CaO19.543 Protein described as fumarate hydratase; transcriptionally regulated by iron; expression greater in high iron; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 997717 998231 - ntar_1264 997717 998231 1 998231 997717 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 998357 998649 - ntar_1265 998357 998649 1 998649 998357 998649 998443 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 998784 999684 - orf19.544 998784 999684 1 999684 998784 999645 999220 orf19.8179|IPF26822.1|IPF4282.2|Contig4-2548_0003|orf6.6756|CA4256|CaO19.8179|RPR2|CaO19.544|IPF4282 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 999771 1001261 + orf19.544.1 999771 1001261 3 999771|999967|1000076 999871|999986|1001261 999837 1000773 PRE6 IPF26808.1|IPF4281.2|Contig4-2548_0002|CA4257 Protein described as alpha-4 subunit of proteasome; reported as macrophage-induced protein and macrophage/pseudohyphal-repressed gene; regulated by Gcn2p and Gcn4p; removed from/reinstated in Assembly 20 (see Locus History) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1000767 1001980 - orf19.547 1000767 1001980 1 1001980 1000767 1001940 1000822 orf19.8182|IPF26795.1|IPF4279.2|orf6.6759|CA4258|RAD27|CaO19.8182|CaO19.547|IPF4279 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1002162 1003341 - orf19.548 1002162 1003341 1 1003341 1002162 1003270 1002197 CDC10 orf19.8183|IPF26797.1|IPF4277.2|Contig4-2070_0004|orf6.6760|CA4259|CaO19.8183|CaO19.548 Septin, required for wild-type cell, hyphal, or chlamydospore morphology; role in virulence and kidney tissue invasion in a mouse model of systemic infection; forms ring at sites of cell division and filaments in mature chlamydospore [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1003456 1003744 + ntar_1266 1003456 1003744 1 1003456 1003744 1003456 1003668 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1003855 1004945 + orf19.549 1003855 1004945 1 1003855 1004945 1004064 1004687 orf19.8184|IPF26811.1|IPF4276.2|Contig4-2070_0001|Contig4-2649_0003|orf6.6761|CA4260|MRPL32|CaO19.8184|CaO19.549|IPF4276 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1004716 1005670 - orf19.550 1004716 1005670 1 1005670 1004716 1005653 1004844 PDX3 orf19.8185|IPF15643.2|IPF4274.2|Contig4-2070_0006|Contig4-2649_0004|orf6.6762|CA4261|CaO19.550 Transcription is regulated upon yeast-hyphal switch; regulated by Nrg1p, Mig1p, and Tup1p; caspofungin repressed; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1006018 1008248 + orf19.551 1006018 1008248 1 1006018 1008248 1006507 1008165 orf19.8186|IPF15641.2|IPF29791.1|Contig4-2649_0006|orf6.1932|CA0795|CaO19.551|IPF15641 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1008215 1009717 - orf19.552 1008215 1009717 1 1009717 1008215 1009717 1008215 orf19.8187|IPF26783.1|IPF15639.2|Contig4-2649_0008|orf6.1931|CA0794|CaO19.8187|ATG22|CaO19.552|IPF15639 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1009971 1011488 - orf19.553 1009971 1011488 1 1011488 1009971 1011488 1009971 orf19.8188|IPF26782.1|IPF16273.2|Contig4-2649_0010|orf6.1930|CA0793|CaO19.553|DTR1|CaO19.8188|IPF16273 [NOT TRANSCRIBED?] Predicted membrane transporter, member of the drug:proton antiporter (12 spanner) (DHA1) family, major facilitator superfamily (MFS) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1011750 1013148 - orf19.554 1011750 1013148 1 1013148 1011750 1013148 1011985 DIT2 orf19.8189|IPF26794.1|IPF20066.2|Contig4-2649_0012|orf6.1929|CA0792|CaO19.8189|CaO19.554|DIT2.3eoc|IPF20066.1 Monooxygenase of the cytochrome P450 family involved in chlamydospore formation; produces N,N'-bisformyl dityrosine from N-formyltyrosine; transcription is regulated by Nrg1p, Mig1p, and Tup1p [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chrR 1013629 1013984 - ntar_1267 1013629 1013984 1 1013984 1013629 1013766 1013629 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1014172 1015698 + orf19.1741 1014172 1015698 1 1014172 1015698 1014172 1015698 DIT1 orf19.9308|IPF15414.2|IPF29325.1|Contig4-2127_0005|orf6.1352|CA0437|CaO19.1741 [NOT TRANSCRIBED?] Protein described as spore wall maturation protein; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1015895 1016309 + orf19.1738.1 1015895 1016309 1 1015895 1016309 1015949 1016236 IPF25583.1|IPF15412.2|Contig4-2127_0004|CA0436|RBL2 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1016296 1018214 - orf19.1738 1016296 1018214 2 1018214|1017869 1018010|1016296 1018054 1016412 UGP1 orf19.9305|orf6.1349|IPF15411.2|IPF19328.2|Contig4-2127_0003|orf6.346|CA0435|CaO19.1738 Protein similar to UTP-glucose-1-phosphaturidyl transferase; localizes to cell surface of yeast-form cells, but not hyphal cells; Hog1p-downregulated; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1018420 1018776 - orf19.1737 1018420 1018776 1 1018776 1018420 1018776 1018420 IPF29327.1|orf6.347|CaO19.1737 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1018895 1019813 - orf19.1736 1018895 1019813 1 1019813 1018895 1019385 1019083 orf19.9304|IPF13574.1|IPF15408.2|Contig4-1840_0002|Contig4-2127_0001|orf6.1348|orf6.348|CaO19.1736 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1019243 1019871 + ntar_1268 1019243 1019871 1 1019243 1019871 1019603 1019827 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1020018 1020133 - ts(gcu)2 1020018 1020133 2 1020133|1020062 1020097|1020018 tS(GCU)2.2 tRNA-Ser predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1020227 1020341 - ts(gcu)1 1020227 1020341 2 1020341|1020271 1020305|1020227 tS(GCU)1.2 tRNA-Ser predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1020818 1021464 + orf19.1735 1020818 1021464 1 1020818 1021464 1020933 1021337 orf19.9303|IPF13577.2|IPF19052.2|Contig4-1840_0001|orf6.1347|CA0434|CaO19.1735|IPF13577 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1021383 1025605 - orf19.1734 1021383 1025605 1 1025605 1021383 1025600 1021437 orf19.9302|IPF25587.1|IPF13578.2|Contig4-3008_0029|orf6.1094|orf6.1346|CA0305|INO80|CaO19.1734 Predicted ORF in Assemblies 19, 20 and 21; heterozygous null mutant displays sensitivity to virgineone [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1026252 1026428 + ntar_1269 1026252 1026428 1 1026252 1026428 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1026879 1027456 + orf19.6318 1026879 1027456 1 1026879 1027456 1026963 1027295 orf19.13695|IPF20835.1|IPF6280.2|Contig4-3056_0003|orf6.5511|CA3285|CaO19.6318|CaO19.13695|IPF6280 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1027309 1031708 - orf19.6317 1027309 1031708 1 1031708 1027309 1031590 1027478 ADE6 orf19.13694|IPF20840.1|IPF6279.2|Contig4-3056_0004|orf6.5510|CA3284|CaO19.6317|CaO19.13694 Enzyme of adenine biosynthesis; not induced during GCN response, in contrast to the S. cerevisiae ortholog; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1031983 1032787 + orf19.6316.4 1031983 1032787 1 1031983 1032787 1032458 1032733 IPF20842.1|IPF6277.2|Contig4-3056_0006|Contig4-3056_0007 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1032710 1034542 - orf19.6316 1032710 1034542 1 1034542 1032710 1034479 1032794 orf19.13693|IPF20825.1|IPF6274.1|Contig4-3056_0009|orf6.5509|CA3283|FMP421|CaO19.13693|CaO19.6316|IPF6274 Predicted membrane transporter, member of the L-amino acid transporter-3 (LAT3) family, major facilitator superfamily (MFS) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1034651 1035632 - orf19.6315 1034651 1035632 1 1035632 1034651 1035522 1034953 orf19.13692|IPF20834.1|IPF6272.2|Contig4-3056_0010|orf6.5508|CA3282|CaO19.6315|CaO19.13692|IPF6272 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1035891 1036853 + orf19.6314 1035891 1036853 1 1035891 1036853 1036065 1036511 RPB8 orf19.13691|IPF20837.1|IPF6271.2|Contig4-3056_0012|orf6.5507|CA3281|CaO19.13691|CaO19.6314 Protein described as a subunit of RNA polymerases I, II, and III; regulated by Gcn4p; repressed in response to amino acid starvation (3-aminotriazole treatment); heterozygous null mutant exhibits resistance to parnafungin [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1036960 1037810 + orf19.6313.2 1036960 1037810 2 1036960|1037177 1037100|1037810 1037082 1037649 IPF20838.1|IPF6269.1|Contig4-3056_0013|CA3280|IPF6269|IPF6269.3 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1038275 1040442 + orf19.6313 1038275 1040442 1 1038275 1040442 1038275 1040434 MNT4 orf19.13690|orf6.5506|IPF20823.1|IPF6268.2|Contig4-3056_0014|Contig4-3056_0015|Contig4-3056_0016|CA3279|CaO19.13690|CaO19.6313|IPF6268 Transcriptionally regulated by iron; expression greater in low iron; similar to mannosyltransferases [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chrR 1040957 1041906 + orf19.6312 1040957 1041906 1 1040957 1041906 1041023 1041778 RPS3 orf19.13689|IPF20833.1|IPF6267.1|Contig4-3056_0018|orf6.5505|CA3278|CaO19.6312|CaO19.13689|RPS3E Putative ribosomal protein; Hog1p-induced; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1042269 1042540 + ntar_1270 1042269 1042540 1 1042269 1042540 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1043145 1043954 + orf19.6311 1043145 1043954 1 1043145 1043954 1043339 1043644 orf19.13688|IPF20839.1|IPF6266.2|Contig4-3056_0022|orf6.5504|CA3277|CaO19.13688|CaO19.6311|IPF6266 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1044276 1047084 - orf19.6310 1044276 1047084 1 1047084 1044276 1046835 1044415 orf19.13687|IPF20822.1|IPF6263.2|Contig4-3056_0025|Contig4-3056_0026|orf6.5503|CA3276|CaO19.13687|CaO19.6310|IPF6263 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chrR 1048130 1050367 - orf19.6309 1048130 1050367 1 1050367 1048130 1050182 1048269 MSS11 orf19.13686|IPF19485.2|IPF17068.2|Contig4-3056_0031|orf6.20|orf6.5502|CA3275|CaO19.6309|IPF17068 Transcriptional activator, binds to Flo8p via a LisH motif to cooperatively activate transcription of hyphal-specific genes; required for hyphal growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1051246 1052111 - orf19.6308 1051246 1052111 1 1052111 1051246 1052111 1051335 orf19.13685|IPF17073.2|IPF12227.2|Contig4-3056_0033|orf6.21|orf6.5501|CA3274|CaO19.6308|IPF12227.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chrR 1051507 1051805 + ntar_1271 1051507 1051805 1 1051507 1051805 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1052080 1053636 - orf19.6307 1052080 1053636 1 1053636 1052080 1053468 1052080 orf19.13684|IPF20829.1|IPF19982.1|Contig4-3056_0034|Contig4-3056_0035|orf6.5500|CA3273|CaO19.6307|CaO19.13684|IPF12227.5f Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chrR 1054024 1054182 - ntar_1272 1054024 1054182 1 1054182 1054024 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1054386 1056134 - orf19.6306 1054386 1056134 1 1056134 1054386 1055989 1054484 orf19.13683|IPF20826.1|IPF12224.2|Contig4-3056_0038|orf6.5499|CA3272|CaO19.6306|ALD4|CaO19.13683 Trimethylaminobutyraldehyde dehydrogenase, the third enzyme of the carnitine biosynthesis pathway [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1056796 1058176 + orf19.6305 1056796 1058176 1 1056796 1058176 1056992 1058101 orf19.13682|IPF20831.1|IPF12223.2|Contig4-3056_0040|orf6.5498|CA3271|CaO19.13682|GLY12|CaO19.6305|GLY2 Hydroxytrimethyllysine aldolase, the second enzyme in the carnitine biosynthesis pathway [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1058343 1059523 + orf19.6304 1058343 1059523 1 1058343 1059523 1058347 1059336 LYS5 orf19.13681|orf6.5497|IPF20830.1|IPF12222.2|Contig4-3056_0041|CA3270|CaO19.6304|CaO19.13681 Phosphopantetheinyl transferase; enzyme of lysine biosynthesis; modifies, and thereby activates, Lys2p alpha-aminoadipate reductase; functional homolog of S. cerevisiae Lys5p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1058663 1058880 - ntar_1273 1058663 1058880 1 1058880 1058663 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1059980 1060825 - orf19.6302 1059980 1060825 1 1060825 1059980 1060825 1059980 PGA39 orf19.13679|IPF20832.1|IPF12221.2|Contig4-3056_0043|orf6.5495|CA3269|CaO19.6302|CaO19.13679|IPF12221 Putative GPI-anchored protein of unknown function [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chrR 1062851 1064347 + orf19.1803 1062851 1064347 1 1062851 1064347 1062991 1064145 CDC43 orf19.9369|IPF14866.2|IPF19031.1|Contig4-2476_0003|orf6.1162|orf6.1576|CA0571|CaO19.1803 Beta subunit of heterodimeric protein geranylgeranyltransferase type I; GGTase I enzyme binds zinc, is Mg-dependent; Cdc42p is GGTase I substrate [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chrR 1063497 1064260 - ntar_1274 1063497 1064260 1 1064260 1063497 1063631 1063497 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1064571 1065906 + orf19.1804 1064571 1065906 1 1064571 1065906 1064655 1065743 orf19.9370|IPF18938.1|IPF14864.1|Contig4-2476_0004|orf6.1161|orf6.1577|CA0572|CaO19.1804|IPF14864 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1066099 1067723 + orf19.1805 1066099 1067723 1 1066099 1067723 1066201 1067559 PEX14 orf19.9371|IPF15186.2|IPF14862.2|Contig4-2476_0006|orf6.1160|orf6.1578|CA0573 Protein not essential for viability; similar to S. cerevisiae Pex14p, which is a peroxisomal protein involved in import of peroxisomal matrix proteins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1067404 1067548 - ntar_1275 1067404 1067548 1 1067548 1067404 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1068806 1069882 + orf19.1806 1068806 1069882 1 1068806 1069882 1068806 1069882 orf19.9373|IPF15183.2|IPF29302.1|Contig4-2476_0010|orf6.1580|CA0574|CaO19.1806|CaO19.9373|IPF15183 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chrR 1070617 1073973 + orf19.1808 1070617 1073973 1 1070617 1073973 1070731 1073841 orf19.8246|orf19.9375|IPF25517.1|IPF15178.2|IPF26665.1|IPF11378.2|Contig4-2129_0007|orf6.443|orf6.1582|CA0575|CA0080|orf19.632|CaO19.9375|CaO19.1808|IPF15178.5eoc|IPF15178 Putative protein of unknown function, transcription is positively regulated by Tbf1p; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chrR 1073701 1074987 - orf19.633 1073701 1074987 1 1074987 1073701 1074798 1073887 IPF26671.1|IPF11379.2|IPF19271.1|Contig4-2129_0003|orf6.444|CA0081|IPF11379 Protein described as a putative methyltransferase; decreased expression in hyphae compared to yeast-form cells; expression regulated during planktonic growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1075536 1076405 - orf19.634 1075536 1076405 1 1076405 1075536 1076405 1075536 orf19.8247|IPF11382.3|IPF29754.1|Contig4-2129_0005|orf6.445|orf6.71|CA0009|CaO19.634|IPF11382|IPF11382.2 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1077795 1078376 - orf19.635 1077795 1078376 1 1078376 1077795 1078376 1077795 orf19.8248|IPF26674.1|IPF11384.2|Contig4-2448_0015|orf6.3522|CA1843|CaO19.635|IPF11364 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction); transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1079980 1080807 - orf19.654 1079980 1080807 1 1080807 1079980 1080807 1079980 orf19.8268|IPF19930.2|orf6.765|CA1844|CIS305|CaO19.654|IFL5.3|IPF19930.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1081731 1082057 - orf19.653 1081731 1082057 1 1082057 1081731 1082057 1081731 IPF29760.1|CaO19.653 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1081927 1084171 + orf19.652 1081927 1084171 1 1081927 1084171 1082058 1084112 orf19.8267|IPF11388.2|IPF16500.2|Contig4-2448_0006|orf6.3530|orf6.764|CA0176|CaO19.652|IPF11388 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1084329 1086052 + orf19.651 1084329 1086052 1 1084329 1086052 1084370 1085959 LYP1 orf19.8266|IPF19150.2|IPF16499.2|Contig4-2448_0003|orf6.3531|orf6.763|CA1853|CaO19.651 Predicted ORF in Assemblies 19, 20 and 21; amphotericin B induced; flucytosine repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1086690 1086908 - ntar_1276 1086690 1086908 1 1086908 1086690 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1087213 1090337 + orf19.649 1087213 1090337 1 1087213 1090337 1087289 1090201 orf19.8264|IPF26659.1|IPF12611.2|orf6.3533|CA1854|CaO19.649|CaO19.8264|IPF12611 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1090337 1091533 - ntar_1277 1090337 1091533 1 1091533 1090337 1090785 1090576 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1090520 1091983 + orf19.647.3 1090520 1091983 1 1090520 1091983 1091608 1091907 IPF26685.1|IPF29762.1 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1095403 1096787 + orf19.646 1095403 1096787 1 1095403 1096787 1095525 1096646 GLN1 orf19.8260|IPF19831.2|IPF15149.2|Contig4-2298_0010|orf6.2713|orf6.313|orf6.3536|CA1855|CaO19.646 Protein described as similar to glutamate synthase; regulated by Tsa1p, Tsa1Bp under H2O2 stress conditions [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1098971 1099068 + th(gug)1 1098971 1099068 2 1098971|1099034 1099007|1099068 tH(GUG)1.2 tRNA-His predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1099522 1101308 + orf19.645.1 1099522 1101308 2 1099522|1099720 1099652|1101308 1099638 1101114 IPF10175.2|IPF17304.3|Contig4-2707_0002|CA6176|VMA13 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1101428 1103400 - orf19.644 1101428 1103400 4 1103400|1102325|1102215|1101840 1102403|1102325|1101906|1101428 1103400 1101428 HGT9 orf19.8258|orf19.8259|HXT4|IPF26668.1|IPF10171.1|Contig4-2707_0003|Contig4-2707_0004|Contig4-2707_0005|orf6.2714|orf6.2715|CA1281|orf19.645|orf19.644.1|IPF10171|CA1282|IPF10171.exon2|IPF10173.2|CA1283|IPF10171.exon1|IPF10171.exon3|IPF10174.2 [NOT TRANSCRIBED?] Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; induced at low (0.2%, compared to 2%) glucose in rich media; intron [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1105224 1109200 + orf19.643 1105224 1109200 1 1105224 1109200 1105224 1109060 orf19.8257|IPF10168.1|IPF29758.1|Contig4-2707_0008|orf6.2716|CA1284|CaO19.643|IPF10168|IPF10168.3 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chrR 1110217 1113399 + orf19.642 1110217 1113399 1 1110217 1113399 1110509 1113283 orf19.8256|IPF26660.1|IPF14629.1|Contig4-2852_0018|orf6.3529|CA1851|SAP155|CaO19.642|CaO19.8256|IPF14629 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1113274 1114315 - orf19.641 1113274 1114315 1 1114315 1113274 1114255 1113353 orf19.8255|IPF26669.1|IPF14630.2|Contig4-2852_0017|orf6.3528|CA1850|CaO19.8255|ERJ5|CaO19.641|IPF14630 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1113590 1113781 + ntar_1278 1113590 1113781 1 1113590 1113781 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1114371 1115300 + orf19.640 1114371 1115300 1 1114371 1115300 1114462 1115175 orf19.8254|IPF26672.1|IPF19932.1|Contig4-2852_0015|orf6.3527|CA1849|CaO19.640|CaO19.8254|IPF19932 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1115333 1116006 + orf19.639.1 1115333 1116006 1 1115333 1116006 1115396 1115671 IPF26682.1|IPF11128.1|Contig4-2852_0014|CA1848|IPF11128 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1115603 1116887 - orf19.639 1115603 1116887 1 1116887 1115603 1116887 1115691 orf19.8253|IPF26666.1|IPF11127.1|Contig4-2852_0013|orf6.3526|CA1847|CaO19.639|CaO19.8253|IPF11127 Predicted ORF in Assemblies 19, 20 and 21; decreased transcription is observed upon fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1116944 1118471 - orf19.638 1116944 1118471 1 1118471 1116944 1118217 1117078 FDH1 orf19.8252|FDH12|IPF26667.1|IPF11124.1|Contig4-2852_0012|orf6.3525|CA1846|CaO19.638|FDH99|CaO19.8252 Putative formate dehydrogenase, oxidizes formate to produce CO2; induced during macrophage infection; fluconazole-downregulated; Mig1p regulated; downregulated by Efg1p under yeast, not hyphal, growth conditions; predicted to be cytosolic [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1119156 1119574 + ntar_1279 1119156 1119574 1 1119156 1119574 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1119434 1120537 - orf19.637 1119434 1120537 1 1120537 1119434 1120441 1119650 SDH2 orf19.8251|orf6.3524|IPF26670.1|IPF11123.1|Contig4-2852_0010|CA1845|CaO19.8251|CaO19.637|IPF11123 Succinate dehydrogenase, Fe-S subunit; localizes to surface of yeast-form cells, but not hyphae; transcriptionally regulated by iron; expression greater in high iron; repressed by nitric oxide; induced during log phase (aerobic growth) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1120666 1121060 + ntar_1280 1120666 1121060 1 1120666 1121060 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1122196 1123023 + orf19.555 1122196 1123023 1 1122196 1123023 1122196 1123023 orf19.8190|orf19.8250|orf6.362|IPF26750.1|IPF20036.1|IPF29759.1|IPF26680.1|IPF19931.2|Contig4-2448_0010|Contig4-2852_0008|orf6.3523|orf6.765|CA0177|orf19.635.1|orf19.636|CIS304|CaO19.8190|CaO19.555|IFL2|IPF20048.1 Protein similar to S. cerevisiae Cis3p, which has a role cell-wall-related processes; predicted Kex2p substrate [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1123938 1124758 - orf19.556 1123938 1124758 1 1124758 1123938 1124646 1124227 orf19.8191|IPF26752.1|IPF15839.1|Contig4-2852_0004|orf6.363|CA0056|CaO19.8191|CaO19.556|IPF15839 Predicted ORF in Assemblies 19, 20 and 21; regulated by Ssn6p; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1125596 1126887 + orf19.557 1125596 1126887 1 1125596 1126887 1125729 1126754 orf19.8192|IPF19891.2|IPF29785.1|Contig4-2852_0001|orf6.2136|CA0928|CaO19.557|IPF19891|IPF19891.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1126728 1129002 - orf19.558 1126728 1129002 1 1129002 1126728 1128907 1127012 GUT1 orf19.8193|IPF26747.1|IPF3751.2|orf6.2137|CA0929|CaO19.8193|CaO19.558 Protein described as glycerol kinase; downregulated upon adherence to polystyrene; greater mRNA abundance observed in a cyr1 homozygous null mutant than in wild type [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1129305 1132754 - orf19.559 1129305 1132754 1 1132754 1129305 1132754 1129305 FGR14 orf19.8194|IPF26753.1|IPF3750.2|Contig4-3107_0004|orf6.2138|CA0930|CaO19.8194|POL92|CaO19.559|Zorro1a Protein encoded in retrotransposon Zorro3 with similarity to retroviral endonuclease-reverse transcriptase proteins; lacks an ortholog in S. cerevisiae; transposon mutation affects filamentous growth [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1132929 1134755 - orf19.562 1132929 1134755 1 1134755 1132929 1134755 1132929 FGR13 orf19.8197|orf19.8621|IPF26285.1|IPF19213.1|IPF26748.1|IPF3748.2|Contig4-2885_0021|Contig4-3028_0029|orf6.2141|orf6.614|CA0931|orf19.1006|CaO19.8197|CaO19.562|IPF3748 Protein encoded in retrotransposon Zorro3 with a potential zinc finger; lacks an ortholog in S. cerevisiae; transposon mutation affects filamentous growth; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1134655 1134908 + ntar_1281 1134655 1134908 1 1134655 1134908 1134705 1134863 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1135076 1135373 + ntar_1282 1135076 1135373 1 1135076 1135373 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1135305 1136529 - orf19.1007 1135305 1136529 1 1136529 1135305 1136506 1135448 orf19.8622|IPF26283.1|IPF3746.1|Contig4-3028_0026|orf6.613|CA0133|KCS1|CaO19.1007|CaO19.8622|IPF3746 Putative transcription factor with bZIP DNA-binding motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1136826 1137140 + orf19.1008 1136826 1137140 1 1136826 1137140 1136826 1137140 IPF29604.1|Contig4-3028_0025|orf6.612|CaO19.1008 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1137127 1137447 + orf19.1009 1137127 1137447 1 1137127 1137447 IPF26287.1|Contig4-3028_0022|Contig4-3028_0024|orf6.611|CaO19.1009 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=true scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1138095 1139569 + orf19.1010 1138095 1139569 1 1138095 1139569 1138164 1139300 MNT3 orf19.8624|KTR1|IPF19565.2|IPF29601.1|Contig4-3028_0019|orf6.2170|orf6.220|KTR3|CA0033|CaO19.1010|CA0952|MNT3.3eoc|IPF19564.1 Protein with similarity to mannosyltransferases; transcription is elevated in cyr1, chk1, nik1, and sln1 homozygous null mutants; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1139044 1141777 - orf19.1011 1139044 1141777 1 1141777 1139044 1141357 1139375 orf19.8625|IPF26282.1|IPF3740.1|Contig4-3028_0018|orf6.2169|CA0951|MNN21|CaO19.8625|CaO19.1011|MNN6 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1142460 1143539 + orf19.1012 1142460 1143539 1 1142460 1143539 1142648 1143109 orf19.8626|IPF26284.1|IPF3737.2|Contig4-3028_0013|orf6.2168|CA0950|APS1|CaO19.1012|CaO19.8626|IPF3737 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1145904 1146425 - orf19.5289 1145904 1146425 1 1146425 1145904 1146425 1146111 orf19.8627|IPF26286.1|IPF29603.1|IPF27470.1|orf6.2167|orf6.3828|orf19.1013|CaO19.5289 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chrR 1146120 1146682 + ntar_1283 1146120 1146682 1 1146120 1146682 1146391 1146618 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1146943 1147922 + orf19.5288.1 1146943 1147922 1 1146943 1147922 1147642 1147827 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1148166 1148494 + ntar_1284 1148166 1148494 1 1148166 1148494 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1148323 1149996 - orf19.5288 1148323 1149996 1 1149996 1148323 1149961 1148654 IFE2 IPF3735.1|Contig4-3028_0005|orf6.3827|YAL60|CA2075|CaO19.5288|BDH2 Protein described as an alcohol dehydrogenase; decreased expression in hyphae compared to yeast-form cells; Efg1p-regulated; fluconazole-induced; Hog1p-induced; increased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1150627 1151480 + ntar_1285 1150627 1151480 1 1150627 1151480 1150627 1150830 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1151582 1152103 + ntar_1286 1151582 1152103 1 1151582 1152103 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1151736 1153484 - orf19.5287 1151736 1153484 1 1153484 1151736 1153364 1151805 IPF3733.2|Contig4-3028_0003|orf6.3826|CA2074|CaO19.5287|IPF3733 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1153857 1155615 + ntar_1287 1153857 1155615 1 1153857 1155615 1154339 1154500 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1155506 1156622 - orf19.5286 1155506 1156622 1 1156622 1155506 1156494 1155628 YCP4 IPF27466.1|Contig4-2561_0001|CA6240|CaO19.5286 Putative flavodoxin; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1157944 1158707 + orf19.5285 1157944 1158707 1 1157944 1158707 1158020 1158619 PST3 IPF27467.1|Contig4-2561_0001|CA6239|CaO19.5285|PST2 Putative flavodoxin; biofilm induced; fungal-specific (no human or murine homolog); protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1158902 1158997 - tr(acg)2 1158902 1158997 2 1158997|1158937 1158962|1158902 tRNA-Arg predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1159028 1159121 - tr(acg)1 1159028 1159121 2 1159121|1159063 1159086|1159028 tRNA-Arg predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1160082 1160396 + orf19.5284 1160082 1160396 1 1160082 1160396 1160082 1160396 IPF27500.1|IPF27469.1|orf6.1943|orf19.3510|CaO19.5284 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1160503 1161567 + orf19.3512 1160503 1161567 1 1160503 1161567 1160503 1161567 IPF12574.2|IPF27468.1|Contig4-2428_0001|orf6.1945|CA0803|orf19.5283|CIS310|CaO19.3512|IFL4 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chrR 1161999 1162806 + orf19.3515 1161999 1162806 1 1161999 1162806 1162068 1162583 IPF12570.2|Contig4-2428_0007|CA0804|CaO19.3515|BNA1|orf6.1948 Putative 3-hydroxyanthranilic acid dioxygenase, involved in NAD biosynthesis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1162553 1163402 - orf19.3516 1162553 1163402 1 1163402 1162553 1163343 1162696 IPF12568.1|Contig4-2428_0008|CA0805|CaO19.3516|IPF12568|orf6.1949 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1163490 1164571 + orf19.3517 1163490 1164571 1 1163490 1164571 1163640 1164479 IPF12567.2|Contig4-2428_0011|CA0806|CaO19.3517|IPF12567|orf6.1950 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1164086 1164787 - ntar_1288 1164086 1164787 1 1164787 1164086 1164787 1164656 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1165669 1166851 + orf19.3518 1165669 1166851 1 1165669 1166851 1165925 1166785 ODC1|IPF12564.1|Contig4-2428_0014|CA0807|CaO19.3518|IPF12564|orf6.1951 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1167166 1168675 + orf19.3519 1167166 1168675 1 1167166 1168675 1167518 1168558 SUA72 orf19.13275|IPF12563.1|IPF21365.1|IPF3791.2|Contig4-2428_0015|orf6.4955|CA0808|orf19.5853|CaO19.3519|SUA71|orf6.1952 Predicted transcriptional regulator; induced during planktonic growth, whereas related SUA71 is downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1168480 1171439 - orf19.5852 1168480 1171439 1 1171439 1168480 1171268 1168632 orf19.13274|IPF12562.2|IPF21357.1|IPF3790.1|Contig4-2975_0001|Contig4-2975_0002|orf6.1953|orf6.4954|CA2883|orf19.3520|CaO19.5852|CaO19.13274|IPF3790 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1171749 1174697 + orf19.5851 1171749 1174697 1 1171749 1174697 1171860 1174652 STE13 orf19.13273|orf6.4953|IPF21356.1|IPF3786.1|Contig4-2975_0004|CA2882|CaO19.5851|CaO19.13273 Protein similar to S. cerevisiae Ste13p, which is a pheromone-processing dipeptidyl aminopeptidase; possible Kex2p substrate; transposon mutation affects filamentous growth; induced by low nitrogen, germ tube formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1174823 1177098 + orf19.5850 1174823 1177098 1 1174823 1177098 1174845 1176989 NOC2 orf19.13272|IPF21359.1|IPF3784.1|Contig4-2975_0006|orf6.4952|RAD4|CA2881|CaO19.13272|CaO19.5850 Protein similar to S. cerevisiae Noc2p; transposon mutation affects filamentous growth; mutation confers hypersensitivity to 5-fluorouracil (5-FU), tubercidin (7-deazaadenosine); downregulated during core stress response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1177023 1178988 - orf19.5849 1177023 1178988 1 1178988 1177023 1178837 1177101 CWT1 orf19.13271|IPF21361.1|IPF3781.2|Contig4-2975_0008|Contig4-2975_0009|orf6.4951|CA2880|CaO19.13271|CaO19.5849|IPF3781 Putative transcription factor; mutant has cell wall defects; transcription increased at stationary phase; has predicted PAS domain and Zn(II) Cys(6)-type DNA-binding region; similar to S. cerevisiae Rds2p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1179205 1181342 - orf19.5848 1179205 1181342 1 1181342 1179205 1181206 1179341 orf19.13270|IPF21360.1|IPF3779.1|Contig4-2975_0013|orf6.4950|CA2879|CaO19.5848|CaO19.13270|IPF3779 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1181681 1185305 - orf19.5847 1181681 1185305 1 1185305 1181681 1185262 1181789 orf19.13269|IPF21366.1|IPF3777.1|Contig4-2975_0014|orf6.4949|CA2878|CaO19.5847|COP1|CaO19.13269|RET1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1185414 1187412 + orf19.5846 1185414 1187412 1 1185414 1187412 1185551 1187035 orf19.13268|IPF21363.1|IPF3776.1|Contig4-2975_0016|orf6.4948|CA2877|TFB2|CaO19.13268|CaO19.5846 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1187101 1189708 - orf19.5845 1187101 1189708 1 1189708 1187101 1189667 1187217 RNR3 orf19.13267|orf6.4947|IPF21358.1|IPF3774.2|Contig4-2975_0017|Contig4-2975_0020|CA2876|RNR2|CaO19.5845|CaO19.13267 Protein described as large subunit of ribonucleotide reductase; transcriptionally regulated by iron; expression greater in low iron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1190064 1190691 - orf19.5844 1190064 1190691 2 1190691|1190575 1190649|1190064 1190691 1190064 orf19.13266|IPF3772.1|IPF17969.2|Contig4-2975_0022|Contig4-3035_0025|orf6.114|orf6.4946|CA2875|CaO19.5844|MEI5 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1190811 1190905 - tc(gca)2 1190811 1190905 2 1190905|1190846 1190869|1190811 tC(GCA)2.2 tRNA-Cys predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1190983 1191080 - tc(gca)1 1190983 1191080 2 1191080|1191018 1191044|1190983 tC(GCA)1.2 tRNA-Cys predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1193369 1193518 + ntar_1289 1193369 1193518 1 1193369 1193518 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1193726 1195281 - orf19.5843 1193726 1195281 1 1195281 1193726 1194904 1194056 orf19.13265|IPF21364.1|IPF4999.2|Contig4-3035_0022|orf6.4945|CA2874|CaO19.5843|IPF4999 Predicted ORF in Assemblies 19, 20 and 21; Plc1p-regulated; greater mRNA abundance observed in a cyr1 homozygous null mutant than in wild type; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1198683 1200647 - orf19.6653 1198683 1200647 1 1200647 1198683 1200535 1198889 orf19.13974|IPF20507.1|IPF5002.2|Contig4-3035_0017|orf6.6550|CA4093|CaO19.6653|CaO19.13974|IPF5002 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1201092 1202706 + orf19.6652 1201092 1202706 1 1201092 1202706 1201128 1202450 DBP8 orf19.13973|IPF20514.1|IPF5004.1|Contig4-3035_0015|orf6.6549|CA4092|CaO19.6652|CaO19.13973 Protein likely to be essential for growth, based on insertional mutagenesis; similar to S. cerevisiae Dbp8p, which is an ATP-dependent helicase involved in rRNA processing; oxidative stress-repressed via Cap1p; flucytosine repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1202343 1203114 - orf19.6650 1202343 1203114 1 1203114 1202343 1203045 1202470 orf19.13971|IPF20525.1|IPF5005.2|Contig4-3035_0014|orf6.6547|CA4091|CaO19.6650|CaO19.13971|IPF5005 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1203215 1205086 + orf19.6649 1203215 1205086 1 1203215 1205086 1203310 1204971 BRF1 orf19.13970|IPF20505.1|IPF5007.2|Contig4-3035_0013|orf6.6546|CA4090|CaO19.6649|CaO19.13970 Component of the general transcription factor for RNA polymerase III (TFIIIB) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1205191 1207649 + orf19.6648 1205191 1207649 1 1205191 1207649 1205251 1207530 SDA1 orf19.13969|IPF20503.1|IPF5009.2|Contig4-3035_0012|orf6.6545|CA4089|CaO19.13969|CaO19.6648|IPF5009 Predicted ORF in Assemblies 19, 20 and 21; transcription is upregulated in both intermediate and mature biofilms [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1207542 1208448 - orf19.6645 1207542 1208448 1 1208448 1207542 1208448 1207777 HMO1 orf19.13966|YDR174|IPF20515.1|IPF5011.2|Contig4-3035_0011|orf6.6542|CA4088|CaO19.6645|CaO19.13966 High mobility group-like protein; activates pseudohyphal growth when expressed in S. cerevisiae; decreased expression in hyphae compared to yeast-form cells; amphotericin B repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1208480 1208878 - orf19.6644 1208480 1208878 1 1208878 1208480 1208878 1208480 orf19.13965|IPF20528.1|IPF5012.1|orf6.6541|CaO19.13965|CaO19.6644 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1209184 1210579 + orf19.6643 1209184 1210579 1 1209184 1210579 1209498 1210523 MCT1 orf19.13964|IPF20516.1|IPF5013.1|Contig4-3035_0008|Contig4-3035_0009|orf6.6540|CA4087|CaO19.6643|CaO19.13964|IPF5013 Putative malonyl-CoA acyl carrier protein acyltransferase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1210458 1211701 - orf19.6642 1210458 1211701 1 1211701 1210458 1211608 1210706 orf19.13963|IPF20521.1|IPF5014.2|Contig4-3035_0007|orf6.6539|CA4086|YIF1|CaO19.6642|CaO19.13963|IPF5014 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1211820 1213417 - orf19.6641 1211820 1213417 1 1213417 1211820 1212791 1211934 orf19.13962|IPF20520.1|IPF5015.2|Contig4-3035_0006|orf6.6538|CA4085|LPF41|CaO19.13962|CaO19.6641|IPF5015 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1213651 1215344 + orf19.6640 1213651 1215344 1 1213651 1215344 1213719 1215155 TPS1 orf19.13961|IPF20512.1|IPF5016.2|Contig4-3035_0004|Contig4-3035_0005|orf6.6537|CA4084|CaO19.6640|CaO19.13961 Trehalose-6-phosphate synthase; role in hyphal growth and virulence in mouse systemic infection; upregulated in presence of human neutrophils; macrophage/pseudohyphal-repressed after 16h; detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1215244 1217084 - orf19.6639 1215244 1217084 1 1217084 1215244 1216834 1215374 orf19.13960|IPF20511.1|IPF5018.2|Contig4-3035_0003|orf6.6536|CA4083|CaO19.13960|CaO19.6639|IPF5018 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1217559 1219257 - orf19.6638 1217559 1219257 1 1219257 1217559 1218941 1217904 PTC4 orf19.13959|IPF20517.1|IPF15571.2|Contig4-2856_0010|orf6.6535|CA4082|CaO19.13959|CaO19.6638 Protein described as a serine/threonine phosphatase, type PP2C; decreased expression in hyphae compared to yeast-form cells [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1219806 1221149 + orf19.6637 1219806 1221149 1 1219806 1221149 1220015 1221043 orf19.13958|IPF20518.1|IPF2523.2|Contig4-2856_0009|orf6.6534|CA4081|CaO19.13958|CaO19.6637|IPF2523 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1220037 1220301 - ntar_1290 1220037 1220301 1 1220301 1220037 1220301 1220158 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1220898 1222132 - orf19.6636 1220898 1222132 1 1222132 1220898 1222081 1221086 orf19.13957|IPF20519.1|IPF2524.2|Contig4-2856_0008|orf6.6533|CA4080|CaO19.6636|CaO19.13957|IPF2524 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1222393 1224013 + orf19.6635 1222393 1224013 1 1222393 1224013 1222438 1223952 orf19.13956|IPF20510.1|IPF2527.2|Contig4-2856_0006|Contig4-2856_0007|orf6.6532|CA4079|CaO19.13956|CaO19.6635|IPF2527 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1224180 1225949 + orf19.6634 1224180 1225949 1 1224180 1225949 1224281 1225819 VMA2 orf19.13955|IPF20509.1|IPF2528.1|Contig4-2856_0005|orf6.6531|CA4078|CaO19.6634|CaO19.13955 Predicted ORF in Assemblies 19, 20 and 21; amphotericin B repressed, caspofungin repressed; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1225864 1228402 - orf19.6632 1225864 1228402 1 1228402 1225864 1228352 1225977 ACO2 orf19.13953|orf6.6529|IPF20499.1|IPF2530.2|Contig4-2856_0004|CA4077|CaO19.13953|CaO19.6632 Protein described as aconitate hydratase 2; regulated by Gcn4p; repressed in response to amino acid starvation (3-aminotriazole treatment); transcriptionally regulated by iron; expression greater in high iron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1228565 1229131 - orf19.6630 1228565 1229131 1 1229131 1228565 1229098 1228694 IPF2532.2|IPF27678.1|Contig4-2856_0002|Contig4-2856_0003|orf6.1187|orf6.6527|CA0356|CaO19.6630|IPF2532 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1229519 1229609 - tp(ugg)5 1229519 1229609 2 1229609|1229554 1229574|1229519 tP(UGG)5.2 tRNA-Pro predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1230106 1230196 - tp(ugg)4 1230106 1230196 2 1230196|1230141 1230161|1230106 tP(UGG)4.2 tRNA-Pro predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1230645 1232244 - orf19.6629 1230645 1232244 1 1232244 1230645 1232111 1230795 ISC1 orf19.13950|IPF2542|IPF18948.2|IPF2542.2|Contig4-2480_0005|orf6.1512|orf6.6526|CA4076|CaO19.6629 Putative phospholipase C, possible neutral sphingomyelinase; not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1232317 1233176 + orf19.6628 1232317 1233176 1 1232317 1233176 1232369 1233088 orf19.13949|IPF18949.2|IPF2555.2|Contig4-2675_0011|orf6.6525|CA4075|CaO19.6628|IPF2555 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1233262 1233335 + tv(aac)4 1233262 1233335 1 1233262 1233335 tV(AAC)4.2 tRNA-Val predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1233687 1234574 + orf19.6627 1233687 1234574 1 1233687 1234574 1233786 1234466 orf19.13948|IPF20523.1|IPF2557.2|Contig4-2675_0010|orf6.6524|CA4074|CaO19.6627|CaO19.13948|IPF2557 Predicted ORF in Assemblies 19, 20 and 21; possibly transcriptionally regulated upon hyphal formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1234648 1234729 + ts(aga)3 1234648 1234729 1 1234648 1234729 tS(AGA)3.2 tRNA-Ser predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1234787 1235820 + orf19.6626 1234787 1235820 1 1234787 1235820 1235065 1235691 orf19.13947|IPF20524.1|IPF2559.1|Contig4-2675_0008|orf6.6523|CA4073|CaO19.13947|CaO19.6626|IPF2559.3 Predicted ORF in Assemblies 19, 20 and 21; possibly transcriptionally regulated upon hyphal formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1235648 1236781 - orf19.6625 1235648 1236781 1 1236781 1235648 1236650 1235823 orf19.13946|IPF20522.1|IPF2560.1|Contig4-2675_0007|orf6.6522|CA4072|CaO19.6625|CaO19.13946|IPF2560 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1236858 1238504 + orf19.6624 1236858 1238504 1 1236858 1238504 1236957 1238465 orf19.13945|IPF20508.1|IPF2561.2|Contig4-2675_0004|orf6.6521|CA4071|CaO19.6624|GYP6|CaO19.13945|IPF2561 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1238641 1239406 + orf19.6623 1238641 1239406 1 1238641 1239406 1238690 1239076 orf19.13944|IPF20532.1|IPF2562.1|Contig4-2675_0003|orf6.6520|CA4070|CaO19.6623|CaO19.13944|IPF2562 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1239119 1243041 - orf19.6621 1239119 1243041 1 1243041 1239119 1242892 1239263 MHP1 orf19.13942|orf19.8092|IPF26876.1|IPF18690.1|IPF20500.1|IPF2566.2|Contig4-2675_0002|orf6.2853|orf6.6518|CA1377|CA4069|orf19.461|CaO19.13942|CaO19.6621 Protein similar to S. cerevisiae Mhp1p, which is involved in microtubule stabilization; transposon mutation affects filamentous growth; possibly transcriptionally regulated upon hyphal formation [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1243153 1243842 - ts(aga)1 1243153 1243842 1 1243842 1243153 tS(AGA)1.2 tRNA-Ser predicted by tRNAscan-SE [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chrR 1244448 1245813 + orf19.460 1244448 1245813 1 1244448 1245813 1244582 1245700 CEK2 orf19.8091|FUS3|IPF26875.1|IPF2568.2|ERK2|Contig4-2547_0006|orf6.2854|CA1378|CaO19.8091|CaO19.460 MAP kinase required for wild-type efficiency of mating; component of the signal transduction pathway that regulates mating; ortholog of S. cerevisiae Fus3p; induced by Cph1p, pheromone; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1245712 1249231 - orf19.459 1245712 1249231 1 1249231 1245712 1248992 1245876 ADP1 orf19.8090|IPF26903.1|IPF2572.2|Contig4-2547_0007|Contig4-2547_0008|orf6.2855|CA1379|CaO19.459|CaO19.8090 Putative PDR-subfamily ABC transporter; similar to WHITE subfamily proteins; gene used for strain identification by multilocus sequence typing [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1249417 1250032 + orf19.458.1 1249417 1250032 1 1249417 1250032 1249616 1249891 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1249765 1251317 - orf19.458 1249765 1251317 1 1251317 1249765 1251275 1249941 orf19.8089|IPF18974.2|IPF2574.2|Contig4-2758_0012|orf6.1428|orf6.2856|CA1380|BCS1|CaO19.458 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1251476 1255565 + orf19.457 1251476 1255565 1 1251476 1255565 1251543 1255457 orf19.8088|IPF2578.1|IPF29835.1|orf6.1427|orf6.2857|CA0476|UBP2|CaO19.457 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1255619 1258939 - orf19.454 1255619 1258939 1 1258939 1255619 1258160 1255743 SFL1 orf19.8085|IPF2580.3|IPF29823.1|Contig4-2758_0008|orf6.1424|orf6.508|CA0475|CaO19.454|IPF2580|IPF2580.2 Protein involved in negative regulation of flocculation and filamentous growth; induced in core caspofungin response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1259080 1259417 - ntar_1291 1259080 1259417 1 1259417 1259080 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1259899 1260287 - ntar_1292 1259899 1260287 1 1260287 1259899 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1272810 1273377 + ntar_1293 1272810 1273377 1 1272810 1273377 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1273601 1276804 + orf19.451 1273601 1276804 1 1273601 1276804 1274197 1276674 SOK1 orf19.8081|IPF26853.1|IPF13595.2|Contig4-2243_0005|orf6.3088|CA1536|CaO19.451|CaO19.8081 Transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1277550 1277760 + ntar_1294 1277550 1277760 1 1277550 1277760 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1278472 1280055 + orf19.3848 1278472 1280055 1 1278472 1280055 1278595 1279887 orf19.11329|IPF16305.2|IPF17469.2|Contig4-2243_0004|orf6.2309|orf6.545|CA1031|CaO19.3848|IPF17469 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1280720 1282321 + orf19.3851 1280720 1282321 1 1280720 1282321 1281002 1282129 orf19.11332|IPF16308.2|IPF28608.1|Contig4-2454_0005|orf6.2312|orf6.542|CA0106|CaO19.3851|IPF16308 Predicted ORF in Assemblies 19, 20 and 21; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1282627 1285360 + ntar_1295 1282627 1285360 1 1282627 1285360 1283992 1284174 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1282658 1285045 - orf19.3852 1282658 1285045 1 1285045 1282658 1285045 1282658 orf19.11333|IPF23377.1|IPF19896.1|Contig4-2454_0004|orf6.2313|CA1032|CaO19.11333|CaO19.3852|IPF19896 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1290136 1292834 + orf19.3854 1290136 1292834 1 1290136 1292834 1290799 1292691 orf19.11335|IPF11548.1|IPF17644.2|Contig4-3046_0003|orf6.290|orf6.5244|CA3094|SAT4|CaO19.3854|IPF11548 Protein similar to S. cerevisiae Sat4p; amphotericin B induced; clade-associated gene expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1293184 1294666 + orf19.3856 1293184 1294666 2 1293184|1293446 1293354|1294666 1293485 1294438 CDC28 orf19.11337|CDK1|IPF23400.1|IPF11549.2|Contig4-3046_0004|orf6.5246|CA3095|CaO19.3856|CaO19.11337 Cyclin-dependent protein kinase, interacts with regulatory subunit Cyb1p; involved in determination of cell morphology during the cell cycle; phosphorylated primarily by Swe1p and phosphorylation is regulated by Hsl1p; intron in 5'-UTR [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1295060 1295919 + orf19.3858 1295060 1295919 1 1295060 1295919 1295093 1295866 orf19.11339|IPF23404.1|IPF11551.2|Contig4-3046_0005|orf6.5248|CA3096|CaO19.3858|CaO19.11339|IPF11551 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1295933 1297285 + orf19.3859 1295933 1297285 1 1295933 1297285 1295933 1297159 orf19.11340|IPF6600|IPF23395.1|IPF6600.2|Contig4-3046_0006|orf6.5249|CA3097|CaO19.11340|CaO19.3859 Predicted ORF in Assemblies 19, 20 and 21; transcription is upregulated in response to treatment with ciclopirox olamine; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1296523 1296731 - ntar_1296 1296523 1296731 1 1296731 1296523 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1297006 1297235 - ntar_1297 1297006 1297235 1 1297235 1297006 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1297457 1298689 + orf19.3861 1297457 1298689 1 1297457 1298689 1297556 1298587 SIS1 orf19.11342|IPF23398.1|IPF6598.2|Contig4-3046_0007|orf6.5251|CA3098|CaO19.3861|CaO19.11342 Predicted ORF in Assemblies 19, 20 and 21; macrophage/pseudohyphal-repressed; heavy metal (cadmium) stress-induced; heterozygous null mutant displays sensitivity to virgineone [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1298865 1300086 + orf19.3862 1298865 1300086 1 1298865 1300086 1298929 1299915 orf19.11343|IPF23399.1|IPF6595.2|Contig4-3046_0009|orf6.5252|CA3099|CaO19.3862|LST8|CaO19.11343 Predicted ORF in Assemblies 19, 20 and 21; heterozygous null mutant displays sensitivity to rapamycin [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1299995 1301887 - orf19.3863 1299995 1301887 1 1301887 1299995 1301887 1299995 orf19.11344|IPF23384.1|IPF6594.2|Contig4-3046_0010|orf6.5253|CA3100|CaO19.11344|CaO19.3863|IPF6594 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1300323 1300581 + ntar_1298 1300323 1300581 1 1300323 1300581 1300323 1300562 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1301099 1301436 + ntar_1299 1301099 1301436 1 1301099 1301436 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1302387 1305042 - orf19.3865 1302387 1305042 1 1305042 1302387 1305024 1302469 RFX1 orf19.11346|IPF23376.1|IPF6593.2|Contig4-3046_0015|orf6.5255|CA3101|CaO19.3865|CaO19.11346|IPF6593 Predicted ORF in Assemblies 19, 20 and 21; similar to S. cerevisiae Rfx1p (DNA-binding transcriptional repressor of DNA damage response); has RFX domain [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1308681 1309805 + orf19.3867 1308681 1309805 1 1308681 1309805 1308722 1309609 RPL7 orf19.11348|IPF23401.1|IPF6586.2|Contig4-3046_0019|orf6.5257|CA3102|RLP7|CaO19.3867|CaO19.11348 Putative ribosomal-related protein; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1309357 1309992 - ntar_1300 1309357 1309992 1 1309992 1309357 1309881 1309717 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1310734 1310903 + ntar_1301 1310734 1310903 1 1310734 1310903 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1312182 1312900 - ntar_1302 1312182 1312900 1 1312900 1312182 1312534 1312334 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1315882 1316235 - orf19.3868 1315882 1316235 1 1316235 1315882 1316235 1315882 IPF28618.1|Contig4-1686_0002|orf6.1003|CaO19.3868 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1316529 1318794 + orf19.3869 1316529 1318794 1 1316529 1318794 1316661 1318415 orf19.11350|IPF17190.2|IPF12184.3|Contig4-2055_0006|orf6.550|orf6.5840|CA0110|CaO19.3869|IPF17190 Predicted ORF in Assemblies 19, 20 and 21; regulated by Tsa1p, Tsa1Bp in minimal media at 37 deg; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1318738 1320456 - orf19.3870 1318738 1320456 1 1320456 1318738 1320356 1318908 ADE13 orf19.11351|IPF19233.2|IPF12183.2|Contig4-2055_0002|Contig4-2055_0004|orf6.551|orf6.5841|CA3547|CaO19.3870 Enzyme of adenine biosynthesis; soluble protein in hyphae; not induced during GCN response, in contrast to the S. cerevisiae ortholog; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1320642 1321567 - orf19.3871 1320642 1321567 1 1321567 1320642 1321396 1320980 orf19.11352|IPF23415.1|IPF12181.1|Contig4-1785_0007|Contig4-2055_0001|orf6.5842|CaO19.3871 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1321723 1322719 + orf19.3872 1321723 1322719 1 1321723 1322719 1321790 1322578 orf19.11353|IPF23403.1|IPF12179.1|Contig4-1785_0002|orf6.5843|CA3548|CaO19.3872|IPF12179 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1322818 1324261 + orf19.3873 1322818 1324261 1 1322818 1324261 1322922 1324076 ARC40 orf19.11354|IPF19474.2|IPF12178.1|Contig4-1785_0001|orf6.32|orf6.5844|CA3549|CaO19.3873 Protein similar to S. cerevisiae Arc40p, which is involved in actin filament organization in S. cerevisiae; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1324031 1325071 - ntar_1430 1324031 1325071 2 1325071|1324164 1324893|1324031 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1326196 1328282 + orf19.3874 1326196 1328282 1 1326196 1328282 1326372 1328222 orf19.11355|IPF23385.1|IPF13228.2|Contig4-2060_0003|orf6.5845|CA3550|CaO19.3874|CaO19.11355|IPF13228 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1328267 1330158 - orf19.3876 1328267 1330158 1 1330158 1328267 1330126 1328267 ZCF19|orf19.11357|IPF23387.1|IPF13229.2|orf6.5847|CA3551|CaO19.3876|CaO19.11357|IPF13229 Predicted zinc-finger protein of unknown function [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chrR 1330469 1331724 + orf19.3877 1330469 1331724 1 1330469 1331724 1330825 1331724 orf19.11358|IPF23396.1|IPF23402.1|IPF13232.2|IPF13231.1|Contig4-2958_0005|Contig4-2958_0006|orf6.5848|orf6.5849|CA3552|IPF13231 Predicted ORF in Assemblies 19, 20 and 21; previously merged with orf19.3878; unmerged from orf19.3878 in a revision of Assembly 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1331788 1333089 + orf19.3878 1331788 1333089 1 1331788 1333089 1331788 1332960 orf19.11359|IPF13232.2|orf6.5849|CA3553|IFA27.5|IFA16.5 Predicted ORF from Assembly 19; merged with orf19.3877 in Assembly 20; unmerged from orf19.3877 in a revision of Assembly 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1333707 1333940 + ntar_1303 1333707 1333940 1 1333707 1333940 1333707 1333940 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1334077 1334646 + orf19.3879 1334077 1334646 1 1334077 1334646 1334077 1334571 orf19.11360|IPF23388.1|IPF23406.1|IPF7771.2|IPF19992.1|Contig4-2958_0008|orf6.5850 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction); overlaps orf19.3879.1, which is a region annotated as blocked reading frame [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chrR 1335225 1336490 - orf19.3881 1335225 1336490 1 1336490 1335225 1336474 1335395 orf19.11362|IPF23397.1|IPF7770.2|Contig4-2958_0010|Contig4-2958_0013|orf6.5852|CA3554|CaO19.3881|CaO19.11362|IPF7770 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1336672 1337495 - orf19.3884 1336672 1337495 1 1337495 1336672 1337424 1336690 FGR50 orf19.11365|IPF23405.1|IPF7766.2|Contig4-2958_0014|orf6.5855|CA3555|CaO19.3884|CaO19.11365|IPF7766 Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1338607 1339843 + orf19.3885 1338607 1339843 1 1338607 1339843 1338755 1339843 orf19.11366|IPF23394.1|IPF7764.2|Contig4-2958_0018|orf6.5856|CA3556|CaO19.3885|CaO19.11366|IPF7764 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chrR 1339795 1341515 - orf19.3886 1339795 1341515 1 1341515 1339795 1341404 1340001 orf19.11367|IPF23392.1|IPF7763.2|Contig4-2958_0019|orf6.5857|CA3557|CaO19.11367|CaO19.3886|IPF7763 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1342267 1342935 - orf19.3887 1342267 1342935 1 1342935 1342267 1342935 1342384 orf19.11368|IPF23408.1|IPF7760.1|Contig4-2958_0022|orf6.5858|CA3558|CaO19.3887|CaO19.11368|IPF7760 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1343044 1344930 - orf19.3888 1343044 1344930 1 1344930 1343044 1344847 1343195 PGI1 orf19.11369|IPF23389.1|IPF7759.1|Contig4-2958_0024|orf6.5859|CA3559|CaO19.11369|CaO19.3888 Protein described as glucose-6-phosphate isomerase, enzyme of glycolysis; antigenic in human; regulated by Efg1p; induced in biofilm, upon adherence to polystyrene; downregulated in the presence of human neutrophils, upon phagocytosis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1345761 1346004 + ntar_1304 1345761 1346004 1 1345761 1346004 1345761 1345910 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1346101 1346388 - orf19.3888.2 1346101 1346388 1 1346388 1346101 1346388 1346101 IPF23413.1|IPF7757.1|Contig4-2958_0027|orf6.968 [NOT TRANSCRIBED?] ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1348994 1350532 - orf19.727 1348994 1350532 1 1350532 1348994 1350532 1348994 orf19.8346|IPF26578.1|IPF20143.1|Contig4-1855_0001|orf6.6016|CA3682|CaO19.8346|CaO19.727|IFV1 Predicted ORF in Assemblies 19, 20 and 21; member of a family encoded by FGR6-related genes in the RB2 repeat sequence; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1354098 1354318 - ntar_1305 1354098 1354318 1 1354318 1354098 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1360231 1360768 + ntar_1306 1360231 1360768 1 1360231 1360768 1360231 1360446 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1363315 1363841 - ntar_1307 1363315 1363841 1 1363841 1363315 1363509 1363372 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1364313 1366109 + orf19.726 1364313 1366109 1 1364313 1366109 1364440 1365888 PPZ1 orf19.8345|IPF26577.1|IPF13615.1|Contig4-2831_0012|orf6.6017|CA3683|CaO19.8345|CaO19.726 Putative protein phosphatase of the Type 1 family (serine/threonine-specific), similar to S. cerevisiae Ppz1p; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1366258 1368106 + orf19.725 1366258 1368106 1 1366258 1368106 1366381 1367172 orf19.8344|IPF26583.1|IPF13613.1|Contig4-2831_0013|orf6.6018|CA3684|CaO19.725|CaO19.8344|IPF13613 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1368041 1371378 - orf19.723 1368041 1371378 1 1371378 1368041 1370532 1368310 BCR1 orf19.8342|USV1|IPF19541.2|IPF19540.1|Contig4-2831_0018|orf6.6|orf6.6020|CA3685|CaO19.723|IPF19540 Transcription factor required for wild-type biofilm formation; not required for hyphal growth; regulates cell-surface-associated genes; has C2H2 zinc finger; filament induced; Tup1p-, Tec1p-, Mnl1p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1378087 1380373 + orf19.721 1378087 1380373 1 1378087 1380373 1378138 1380198 orf19.8340|IPF12829.2|IPF29720.1|Contig4-1601_0001|orf6.1093|CA0304|CaO19.8340|GRC3|CaO19.721|IPF12829 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1380803 1381450 + orf19.720 1380803 1381450 1 1380803 1381450 1380803 1381450 GST3 orf19.8339|IPF17507.2|IPF19366.2|Contig4-1601_0003|orf6.1092|orf6.271|CA0303|CaO19.720|IPF17507 Expression is regulated upon white-opaque switching; upregulated in the presence of human neutrophils; peroxide-induced; induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chrR 1381801 1384163 + orf19.719 1381801 1384163 1 1381801 1384163 1381953 1383854 orf19.8338|IPF14027.3|IPF17505.2|Contig4-2196_0004|orf6.2640|orf6.272|CA0043|CaO19.719|HRD1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1383830 1386120 - orf19.718 1383830 1386120 1 1386120 1383830 1386011 1383936 RRN11 orf19.8337|IPF14026.2|IPF29721.1|Contig4-2196_0001|orf6.2639|orf6.273|CA1240|CaO19.718|IPF14026 Putative RNA polymerase I subunit [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1386259 1388210 - orf19.717 1386259 1388210 1 1388210 1386259 1388174 1386474 HSP60 orf19.8336|orf6.2638|IPF26576.1|IPF14025.2|Contig4-2196_0002|CA1239|CaO19.8336|CaO19.717 Protein described as mitochondrial heat shock protein; soluble protein in hyphae; transcription is regulated by Nrg1p; transcriptionally regulated by iron; expression greater in high iron; heavy metal (cadmium) stress-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1388754 1389818 - orf19.716 1388754 1389818 1 1389818 1388754 1389695 1389195 orf19.8335|IPF15781.2|IPF29722.1|Contig4-2069_0010|orf6.2637|CA1238|CaO19.716|CaO19.8335|IPF15781 Predicted ORF in Assemblies 19, 20 and 21; regulated by Nrg1p, Tup1p; transcription is repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1390531 1391328 + orf19.715 1390531 1391328 1 1390531 1391328 1390665 1391147 orf19.8334|IPF15784.1|IPF13386.1|Contig4-2069_0007|orf6.2636|orf6.409|CA1237|CaO19.715|IPF15784 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1391056 1392389 - orf19.714 1391056 1392389 1 1392389 1391056 1391937 1391278 orf19.8333|IPF15785.2|IPF13387.1|Contig4-1948_0007|Contig4-2069_0006|orf6.2635|orf6.408|CA1236|YPT6|CaO19.714 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1392588 1393219 + orf19.713 1392588 1393219 1 1392588 1393219 1392686 1393102 orf19.8332|IPF20079.1|IPF20037.1|Contig4-1948_0005|Contig4-2069_0002|orf6.2634|orf6.407|CA1235|CaO19.713|IPF20079 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1393341 1396336 + orf19.712 1393341 1396336 1 1393341 1396336 1393368 1396103 KIP1 orf19.8331|IPF13390.2|IPF29716.1|Contig4-1948_0002|Contig4-1948_0004|orf6.2633|CA6177|CaO19.712 Non-essential kinesin from the bipolar (Kinesis-5) family; involved in formation of the mitotic spindle [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1396638 1397148 - ntar_1308 1396638 1397148 1 1397148 1396638 1397067 1396726 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1399918 1401161 - orf19.916 1399918 1401161 1 1401161 1399918 1400912 1400136 IPF19231.1|orf6.569|CA0117|CaO19.916|IPF19231 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1401527 1404571 - orf19.915 1401527 1404571 1 1404571 1401527 1404115 1401527 IPF17975.2|orf6.568|CA0116|CaO19.915|IPF17975 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=H scenario_last_exon=H] Ca21chrR 1404993 1405217 - ntar_1309 1404993 1405217 1 1405217 1404993 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1406210 1406908 + orf19.693 1406210 1406908 1 1406210 1406908 1406210 1406908 IPF18511.2|IPF16201.2|Contig4-1704_0003|orf6.4014|orf6.456|CA0085|CaO19.693|IPF16201 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1408712 1410459 - orf19.695 1408712 1410459 1 1410459 1408712 1410390 1409092 RGS2 orf19.8314|IPF18512|IPF26603.1|IPF18512.1|orf6.4013|CA2209|CaO19.8314|CaO19.695 Protein of RGS superfamily; not essential for viability; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1411399 1411703 - ntar_1310 1411399 1411703 1 1411703 1411399 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1414480 1414718 + ntar_1311 1414480 1414718 1 1414480 1414718 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1414985 1415300 - ntar_1312 1414985 1415300 1 1415300 1414985 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1415420 1416795 - ntar_1313 1415420 1416795 1 1416795 1415420 1415797 1415645 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1415744 1415961 + ntar_1314 1415744 1415961 1 1415744 1415961 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1417414 1417984 + ntar_1315 1417414 1417984 1 1417414 1417984 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1418537 1420156 + orf19.696 1418537 1420156 1 1418537 1420156 1418717 1420129 STE2 orf19.8315|orf6.4012|orf 6.4012|IPF26602.1|IPF17255.2|CA2208|CaO19.8315|CaO19.696|IPF17255 Receptor for alpha factor mating pheromone, MFalpha; required for a-type cells to respond to alpha factor, for opaque a-form mating and white a-form response; possible Kex2p substrate; a-specific, alpha-factor induced, A1-Alpha2p repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1420209 1420469 - ntar_1316 1420209 1420469 1 1420469 1420209 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1420422 1421886 + orf19.697 1420422 1421886 1 1420422 1421886 1420445 1421791 orf19.8316|IPF12169.2|IPF29734.1|Contig4-1763_0006|orf6.4011|CA2207|CaO19.697|IPF12169 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1421078 1421277 - ntar_1317 1421078 1421277 1 1421277 1421078 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1422007 1424679 + ntar_1318 1422007 1424679 1 1422007 1424679 1422352 1422561 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1424680 1426481 - orf19.698 1424680 1426481 1 1426481 1424680 1426316 1424832 orf19.8317|IPF26601.1|IPF12173.2|Contig4-2015_0006|orf6.4010|CA2206|CaO19.698|CaO19.8317|IPF12173 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1426735 1427295 + ntar_1319 1426735 1427295 1 1426735 1427295 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1426764 1427344 - orf19.699 1426764 1427344 1 1427344 1426764 1427203 1426826 orf19.8318|IPF26611.1|IPF17671.2|Contig4-2015_0004|orf6.4009|CaO19.8318|CaO19.699 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1428983 1429194 + ntar_1320 1428983 1429194 1 1428983 1429194 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1429358 1431299 + orf19.700 1429358 1431299 1 1429358 1431299 1429476 1431299 SEO1 orf19.8319|orf6.3324|IPF12176.1|IPF29733.1|SEO2|Contig4-3021_0009|orf6.4008|CA2205 Protein with similarity to permeases; transcription is negatively regulated by Sfu1p; flucytosine induced; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chrR 1431816 1432259 - ntar_1321 1431816 1432259 1 1432259 1431816 1432195 1431950 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1433938 1436157 + orf19.701 1433938 1436157 1 1433938 1436157 1433938 1436157 CFL11 orf19.8320|IPF26596.1|IPF7992.1|FRE8|CFL96|CFL9|Contig4-2984_0006|orf6.3325|CA1701|CaO19.8320|CaO19.701 Predicted ORF in Assemblies 19, 20 and 21; similar to ferric reductase Fre10p; flucytosine repressed; possibly adherence-induced [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1436235 1439702 - orf19.702 1436235 1439702 1 1439702 1436235 1439673 1436356 orf19.8321|IPF26613.1|IPF7990.1|Contig4-2984_0007|orf6.3326|CA1702|CaO19.702|ECM32|CaO19.8321|HEL1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1439767 1440402 + ntar_1322 1439767 1440402 1 1439767 1440402 1440124 1440360 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1439828 1440773 - orf19.703 1439828 1440773 2 1440773|1440625 1440697|1439828 1440700 1439889 orf19.8322|IPF26608.1|IPF7987.1|Contig4-2984_0009|orf6.3327|CA1703|CaO19.703|CPD1|CaO19.8322|IPF7987 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1440899 1441779 - orf19.704 1440899 1441779 1 1441779 1440899 1441728 1440949 SOL3 orf19.8323|IPF26605.1|IPF19927.1|Contig4-2984_0011|orf6.3328|CA1704|CaO19.8323|CaO19.704 Predicted ORF in Assemblies 19, 20 and 21; macrophage-downregulated protein abundance; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1441975 1443403 - orf19.705 1441975 1443403 1 1443403 1441975 1443358 1442009 GCN5 orf19.8324|IPF26604.1|IPF7983.2|Contig4-2984_0012|orf6.3329|CA1705|CaO19.8324|CaO19.705 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to 5-fluorouracil (5-FU) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1443574 1445255 + orf19.706 1443574 1445255 1 1443574 1445255 1443627 1445189 NMD3 orf19.8325|IPF12208.2|IPF7981.1|Contig4-2984_0015|orf6.1726|orf6.3330|CA1706|CaO19.706 Predicted ORF in Assemblies 19, 20 and 21; downregulated in core stress response; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1445405 1447436 + orf19.707 1445405 1447436 1 1445405 1447436 1445476 1447395 APG7 orf19.8326|IPF12207.1|IPF29732.1|Contig4-2984_0019|orf6.1727|CA0661|ATG7|CaO19.707 Protein not essential for viability; similar to S. cerevisiae Atg7p, which is an E1 protein conjugation enzyme involved in protein-vacuolar targeting and autophagy [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1447583 1450209 + orf19.708 1447583 1450209 1 1447583 1450209 1447594 1450209 orf19.8327|IPF26595.1|IPF12206.1|Contig4-2984_0022|orf6.1728|CA0662|SPC97|CaO19.708|CaO19.8327 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1450253 1451168 - orf19.709 1450253 1451168 1 1451168 1450253 1451118 1450351 PUP2 orf19.8328|IPF26606.1|IPF12205.1|Contig4-2984_0023|Contig4-2984_0024|orf6.1729|CA0663|CaO19.709|CaO19.8328 Alpha5 subunit of the 20S proteasome; macrophage/pseudohyphal-repressed; regulated by Gcn2p and Gcn4p; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1451325 1453153 - orf19.1860 1451325 1453153 2 1453153|1452663 1453055|1451325 1453087 1451449 LSC2 orf19.9416|orf19.8329|orf6.1730|IPF25466.1|IPF25436.1|IPF4686.3|IPF19007.1|IPF26609.1|IPF12204.2|Contig4-2797_0017|Contig4-2984_0026|orf6.2420|CA6196|CA0664|orf19.710|IPF19007.3eoc Protein described as beta subunit of succinate-CoA ligase; transcription regulated by Mig1p and Tup1p; transcriptionally regulated by iron; expression greater in high iron; filament induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1453663 1454909 - orf19.1857 1453663 1454909 1 1454909 1453663 1454635 1453958 orf19.9415|IPF4684|IPF25474.1|IPF4684.1|Contig4-3021_0004|orf6.5624|CA3375|CaO19.9415|SPT1|CaO19.1857 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1453811 1454042 + ntar_1323 1453811 1454042 1 1453811 1454042 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1455035 1455288 - ntar_1324 1455035 1455288 1 1455288 1455035 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1455506 1456825 + orf19.1856 1455506 1456825 2 1455506|1455698 1455604|1456825 1455568 1456683 orf19.9414|IPF25473.1|IPF4683.2|Contig4-3021_0006|orf6.5623|CA3374|IPF4683 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1456400 1456727 - ntar_1325 1456400 1456727 1 1456727 1456400 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1457179 1457411 + ntar_1326 1457179 1457411 1 1457179 1457411 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1457457 1459271 - orf19.1855 1457457 1459271 1 1459271 1457457 1459271 1457457 orf19.9413|orf6.3324|IPF25469.1|IPF19985.1|SEO2|SEO1|Contig4-3021_0009|Contig4-3021_0010|orf6.4008|orf6.5622|CA3373|CaO19.1855|SEO11|CaO19.9413 Predicted membrane transporter, member of the anion:cation symporter (ACS) family, major facilitator superfamily (MFS); Gcn4p-regulated; flucytosine induced; ketoconazole-repressed; oxidative stress-induced via Cap1p [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chrR 1459044 1459371 + ntar_1327 1459044 1459371 1 1459044 1459371 1459162 1459371 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1460815 1461605 - orf19.1854 1460815 1461605 1 1461605 1460815 1461352 1461035 HHF22 orf19.9412|IPF25481.1|IPF4677.1|HHF2|orf6.5621|CA3372|CaO19.1854|CaO19.9412 Putative histone H4; regulated by Efg1p; flucytosine, fluconazole-induced; amphotericin B, caspofungin repressed; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1462114 1462865 + orf19.1853 1462114 1462865 1 1462114 1462865 1462310 1462720 HHT2 orf19.9411|IPF25478.1|IPF4676.1|Contig4-3021_0017|CA3371|CaO19.9411|CaO19.1853|HHT22 Protein described as histone H3; farnesol regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1462867 1463674 + orf19.1852 1462867 1463674 1 1462867 1463674 1462928 1463452 orf19.9410|IPF25475.1|IPF4674.2|Contig4-3021_0019|Contig4-3021_0020|orf6.5619|CA3370|CaO19.1852|CaO19.9410|IPF4674 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1463484 1464758 - orf19.1850 1463484 1464758 1 1464758 1463484 1464400 1463555 SIW14 orf19.9408|IPF25472.1|IPF4672.1|Contig4-3021_0022|orf6.5617|CA3369|CaO19.9408|CaO19.1850|IPF4672 Putative protein phosphatase of the PTP family (tyrosine-specific), similar to S. cerevisiae Siw14p; mutant shows virulence defect [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1464866 1467165 + orf19.1849 1464866 1467165 1 1464866 1467165 1464965 1467118 orf19.9407|IPF25468.1|IPF4671.2|Contig4-3021_0024|Contig4-3021_0025|orf6.5616|CA3368|CaO19.1849|CaO19.9407|IPF4671 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1466791 1467527 - orf19.1848.1 1466791 1467527 2 1467527|1467400 1467470|1466791 1467472 1467188 IPF25467.1|IPF4669.1 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1467667 1469569 - orf19.1847 1467667 1469569 1 1469569 1467667 1469568 1467679 ARO10 orf19.9405|IPF4667.1|IPF29286.1|Contig4-3021_0028|orf6.5614|CA3367|CaO19.1847|CaO19.9405|IPF4667 Aromatic decarboxylase of the Ehrlich fusel oil pathway of aromatic alcohol biosynthesis; pH-regulated (alkaline downregulated); protein abundance is affected by URA3 expression in the CAI-4 strain background [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1467717 1469002 + ntar_1328 1467717 1469002 1 1467717 1469002 1468505 1468981 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1470656 1472911 - orf19.1844 1470656 1472911 1 1472911 1470656 1472911 1470656 orf19.9403|IPF4664.2|IPF29287.1|IPF19399.2|FRE4|CFL91|FRE43|Contig4-3021_0032|orf6.184|orf6.5612|CA6264|CA3366|orf19.1845|FRE43.5f [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21; similar to ferric reductase Fre10p [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1474122 1474203 - ts(aga)2 1474122 1474203 1 1474203 1474122 tS(AGA)2.2 tRNA-Ser predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1474702 1475590 + ntar_1329 1474702 1475590 1 1474702 1475590 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1475415 1477426 - orf19.1843 1475415 1477426 1 1477426 1475415 1477277 1475586 ALG6 orf19.9402|IPF25471.1|IPF4661.2|Contig4-3021_0036|Contig4-3021_0037|orf6.5611|CA3365|CaO19.1843|CaO19.9402 Putative glucosyltransferase involved in cell wall mannan biosynthesis; transcription is elevated in chk1, nik1, and sln1 homozygous null mutants; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1479356 1484522 + orf19.1842 1479356 1484522 1 1479356 1484522 1479657 1484333 orf19.9401|CDC25|IPF18345.2|IPF16030.2|Contig4-2086_0003|orf6.1252|orf6.5609|orf6.5610|CA0382|CaO19.1842|IPF16030 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1484586 1485915 + orf19.1841 1484586 1485915 1 1484586 1485915 1484684 1485808 orf19.9399|IPF17745.2|IPF16028.2|Contig4-2086_0001|orf6.119|orf6.1253|CA0383|CaO19.1841|IPF16028 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1486068 1487230 + orf19.178 1486068 1487230 1 1486068 1487230 1486178 1487143 IPF17945.1|orf6.120|orf6.160|CA0025|CaO19.178|IPF17945 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1486882 1487295 - ntar_1330 1486882 1487295 1 1487295 1486882 1487295 1487083 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1487316 1489418 + orf19.2370 1487316 1489418 1 1487316 1489418 1487334 1489376 DSL1 orf19.9906|IPF19559.1|IPF24944.1|IPF19558.1|orf6.161|orf6.4768|CA2751|orf19.179|CaO19.2370|CaO19.9906|IPF19558 Protein similar to S. cerevisiae Dsl1p, which is a member of the t-SNARE complex of the endoplasmic reticulum [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1489395 1489933 - orf19.2369.1 1489395 1489933 1 1489933 1489395 1489772 1489548 ATX1 IPF24942.1|IPF11464.1|Contig4-2581_0001|CA2750 ORF Predicted by Annotation Working Group; flucytosine induced; decreased expression observed in an ssr1 homozygous null mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1490195 1491931 + orf19.2369 1490195 1491931 1 1490195 1491931 1490389 1491879 orf19.9905|IPF24946.1|IPF11465.2|Contig4-2581_0002|orf6.4767|CA2749|CaO19.9905|ORC5|CaO19.2369|IPF11465 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1491394 1493202 - orf19.2368 1491394 1493202 1 1493202 1491394 1493143 1491899 orf19.9904|IPF18502.2|IPF11466.2|Contig4-2581_0003|orf6.4766|CA2748|LIN1|CaO19.2368|IPF11466 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1493293 1494517 + orf19.2367 1493293 1494517 1 1493293 1494517 1493326 1493772 orf19.9903|IPF18501.2|IPF11467.2|Contig4-2581_0004|orf6.4073|orf6.4765|CA2747|CaO19.2367|IPF11467 Protein of unknown function; transcription is negatively regulated by Rim101p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1496790 1499387 + orf19.2366 1496790 1499387 1 1496790 1499387 1496790 1499387 orf19.9902|IPF11469.2|IPF29125.1|Contig4-2581_0007|orf6.4074|CA2248|CaO19.2366|CaO19.9902|IPF11469 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1499474 1506338 - orf19.2365 1499474 1506338 1 1506338 1499474 1506184 1499549 POL2 orf19.9901|IPF24950.1|IPF14265.2|Contig4-2581_0008|orf6.4075|CA2249|CaO19.9901|CaO19.2365 Protein described as DNA polymerase epsilon; transcriptionally induced by interaction with macrophage; transcription is regulated by Tup1p; periodic mRNA expression, peak at cell-cycle G1/S phase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1507121 1510282 + orf19.2364 1507121 1510282 1 1507121 1510282 1507154 1509994 MIS11 orf19.9900|IPF24960.1|IPF12851.2|Contig4-2886_0001|Contig4-2886_0002|orf6.4076|CA2250|CaO19.2364|ADE3|CaO19.9900 Similar to precursor of mitochondrial C1-tetrahydrofolate synthase; putative protein of glycine catabolism; downregulated by Efg1p; fluconazole-induced; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1510473 1511444 + orf19.2363 1510473 1511444 1 1510473 1511444 1510636 1511181 orf19.9899|IPF24951.1|IPF12845.2|Contig4-2886_0003|orf6.4077|CA2251|FMP31|CaO19.9899|CaO19.2363|IPF12845 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1511297 1512446 - orf19.2362 1511297 1512446 1 1512446 1511297 1512321 1511476 orf19.9898|IPF12844.2|IPF29130.1|Contig4-2886_0004|orf6.4078|CA2252|CaO19.9898|CaO19.2362|IPF12844 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1512678 1514340 + orf19.2361 1512678 1514340 1 1512678 1514340 1512731 1514140 SPT10 orf19.9897|IPF24947.1|IPF16032.3|Contig4-2886_0006|orf6.4079|orf6.609|CA0132|CaO19.2361|IPF16032.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1514190 1521964 - orf19.2360 1514190 1521964 2 1521964|1521323 1521866|1514190 1521155 1514505 URA2 orf19.9896|IPF10801.3|IPF29131.1|Contig4-2886_0007|Contig4-2886_0008|orf6.2755|orf6.610|CA1315|CaO19.2360|URA2.5eoc|IPF10801.2 Predicted ORF in Assemblies 19, 20 and 21; flucytosine induced; macrophage/pseudohyphal-induced; intron in 5'-UTR [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1523629 1525662 - orf19.2356 1523629 1525662 1 1525662 1523629 1525254 1523701 CRZ2 orf19.9892|IPF24945.1|IPF10795.2|Contig4-2886_0011|orf6.1328|orf6.2759|CA0424|CaO19.2356|IPF10795 Putative transcription factor; zinc finger; similar to S. cerevisiae Crz1p; homozygous crz1, not crz2, null mutation suppresses fluconazole resistance of homozygous cka2 null (defective in CK2 kinase ); Rim101p-downregulated at pH 8 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1529433 1530051 + ntar_1331 1529433 1530051 1 1529433 1530051 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1532299 1535813 - orf19.1816 1532299 1535813 1 1535813 1532299 1535813 1532346 ALS3 orf19.9891|orf19.9379|ALS8|IPF25511.1|IPF12561.3|IPF24952.1|IPF12997.2|orf6.2760|ALS2|ALS3-1|CA0591|CA0448|orf19.2355|ALS10|ALS3.5eoc|orf6.1614|IPF12561.2 Adhesin; ALS family; role in epithelial adhesion, endothelial invasiveness; allelic variation in adhesiveness; immunoprotective in mice; predicted GPI-anchor cell wall protein; macrophage, hyphal induced, pH, Nrg1p, Rfg1p, Tup1p regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chrR 1536072 1536789 - ntar_1332 1536072 1536789 1 1536789 1536072 1536334 1536212 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1537016 1537181 + ntar_1333 1537016 1537181 1 1537016 1537181 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1538626 1539607 + orf19.1815 1538626 1539607 1 1538626 1539607 1538777 1539514 orf19.9378|IPF12555.2|IPF29299.1|Contig4-2343_0002|orf6.1128|orf6.1615|CA0323|TIF6|CaO19.1815|CDC95 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1540006 1546056 + orf19.1814 1540006 1546056 1 1540006 1546056 1540104 1545887 orf19.9377|IPF14337.3|IPF29300.1|orf6.1129|orf6.1175|orf6.1616|CA0324|STT4|CaO19.1814|IPF14337.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1547572 1550633 + orf19.1813 1547572 1550633 1 1547572 1550633 1547993 1550428 FLC2 orf19.9376|IPF25512.1|IPF19026.1|Contig4-3058_0030|orf6.539|orf6.1174|orf6.540|CA0349|orf19.784|orf19.785|CaO19.9376|CFP1|CaO19.1813|IPF19026 Protein involved in heme uptake; putative FAD transporter, similar to S. cerevisiae Flc2p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1550663 1552991 - orf19.8 1550663 1552991 1 1552991 1550663 1552991 1550784 orf19.7681|IPF11570.2|IPF29984.1|orf6.506|CA0099|CaO19.8|IPF11570.5eoc Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1553211 1554560 - orf19.9 1553211 1554560 1 1554560 1553211 1554425 1553265 orf19.7682|IPF11569.2|IPF18915.2|Contig4-1666_0002|orf6.1707|orf6.507|CA0100|CaO19.9|IPF11569 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1555143 1556768 - orf19.10 1555143 1556768 1 1556768 1555143 1556768 1555221 ALK8 orf19.7683|IPF27231.1|IPF11568.1|Contig4-2506_0001|orf6.1706|CA0651|CaO19.7683|CaO19.10 Alkane-inducible cytochrome P450; catalyzes hydroxylation of lauric acid to hydroxylauric acid; overproduction causes fluconazole resistance in a wild-type background and causes multidrug resistance in a cdr1 cdr2 double mutant background [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chrR 1555249 1555467 + ntar_1334 1555249 1555467 1 1555249 1555467 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1557553 1558272 - orf19.11 1557553 1558272 1 1558272 1557553 1558272 1557553 orf19.7684|orf6.1705|IPF27233.1|IPF11566.1|Contig4-2506_0003|CA0650|CaO19.11|CaO19.7684|IPF11566 Gene transcription regulated by Mig1p and Tup1p; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1559103 1560598 + orf19.734 1559103 1560598 1 1559103 1560598 1559103 1560521 GLK1 orf19.7686|orf19.8353|IPF27232.1|IPF11564.1|IPF26579.1|IPF16544.2|Contig4-1499_0002|Contig4-2506_0004|orf6.1703|orf6.6009|CA0263|orf19.13|CaO19.734|CaO19.8353 Putative glucokinase; transcription is regulated upon yeast-hyphal switch; transcriptionally regulated by Efg1p; fluconazole-induced; induced in core stress response; shows colony morphology-related gene regulation by Ssn6p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chrR 1560607 1561994 - orf19.733 1560607 1561994 1 1561994 1560607 1561994 1560654 orf19.8352|IPF26581.1|IPF20141.1|Contig4-2506_0007|orf6.6010|ZSP12|CaO19.8352|CaO19.733 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chrR 1563061 1564244 + orf19.732 1563061 1564244 1 1563061 1564244 1563333 1564181 orf19.8351|IPF26584.1|IPF8391.2|Contig4-2668_0006|orf6.6011|CA3677|SOU3|CaO19.732|CaO19.8351 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1564459 1565987 + orf19.731 1564459 1565987 1 1564459 1565987 1564484 1565881 EMP46 orf19.8350|IPF26580.1|IPF8392.1|Contig4-2668_0003|orf6.6012|CA3678|CaO19.731|CaO19.8350|IPF8392 Protein similar to S. cerevisiae Emp46p; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1566291 1568930 + orf19.730 1566291 1568930 1 1566291 1568930 1566291 1568930 IPF20142.1|orf6.6013|CA3679|IPF20142 Predicted ORF in Assembly 20 and 21 (see Locus History); transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chrR 1569226 1570971 + orf19.6152 1569226 1570971 1 1569226 1570971 1569226 1570809 orf19.13571|IPF9406.2|IPF27802.1|Contig4-2953_0017|orf6.5662|CA3407|CaO19.6152|IPF9406 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1571012 1571815 + orf19.6151 1571012 1571815 1 1571012 1571815 1571076 1571552 ARC15 orf19.13570|IPF20992.1|IPF9407.2|Contig4-2953_0015|orf6.5663|CA3408|CaO19.6151|CaO19.13570|IPF9407 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to cytochalasin D [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1571679 1574889 - orf19.6148 1571679 1574889 1 1574889 1571679 1574889 1571767 orf19.13567|IPF21005.1|IPF9410.2|Contig4-2953_0014|orf6.5666|CA3409|CaO19.6148|CaO19.13567|IPF9410 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chrR 1573880 1574160 + ntar_1335 1573880 1574160 1 1573880 1574160 1574023 1574160 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1576180 1576839 + orf19.6147 1576180 1576839 1 1576180 1576839 1576213 1576782 orf19.13566|IPF20993.1|IPF9411.2|Contig4-2953_0011|orf6.5667|CA3410|CaO19.6147|CaO19.13566|IPF9411 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1576765 1577873 - orf19.6146 1576765 1577873 1 1577873 1576765 1577798 1577043 CLG1 orf19.13565|IPF9413.1|IPF27804.1|Contig4-2953_0010|orf6.5668|CA3411|CaO19.6146|CaO19.13565|IPF9413 Transcription is regulated upon yeast-hyphal switch [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1579271 1581760 - orf19.6143 1579271 1581760 1 1581760 1579271 1581537 1579423 orf19.13562|IPF9238.1|IPF27800.1|Contig4-2953_0005|orf6.5671|CA3412|FAO1|CaO19.6143|IPF9238 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1582097 1582702 - orf19.6142 1582097 1582702 1 1582702 1582097 1582702 1582097 orf19.13561|IPF20989.1|IPF9239.2|Contig4-2953_0004|orf6.5672|CA3413|CaO19.6142|CaO19.13561|IPF9239 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1582821 1584693 - orf19.6141 1582821 1584693 1 1584693 1582821 1584628 1582931 HGT16 orf19.13560|IPF20980.1|IPF9240.2|Contig4-2953_0003|orf6.5673|CA3414|QUP2|CaO19.13560|CaO19.6141|IPF9240 Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; gene has intron; expressed in rich medium with 2% glucose [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1585765 1587170 + orf19.6140 1585765 1587170 1 1585765 1587170 1586310 1587170 FRE30 orf19.13559|FRE30.53|orf6.5674|CA3415|FRE30.53f|IPF17765.2 Protein with similarity to ferric reductases; downregulated in response to amphotericin B, estradiol, or ciclopirox olamine, and upregulated by interaction with macrophage; un-merged from orf19.6139 in a revision of Assembly 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1587188 1588693 + orf19.6139 1587188 1588693 1 1587188 1588693 1587228 1588439 FRE7 orf19.13558|IPF20984.1|IPF17763.2|FRE3|CFL1|CFL93|orf6.5675|CA3416|FRE30.3|FRE30.3f Protein similar to ferric reductase Fre10p; transcription is downregulated in response to treatment with ciclopirox olamine or 17-beta-estradiol; transcriptionally induced by alkaline conditions or interaction with macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1589637 1591890 + orf19.6138 1589637 1591890 1 1589637 1591890 1589637 1591829 orf19.13557|IPF20976.1|IPF12773.2|CFL93|FRE6|FRE41|Contig4-2158_0004|orf6.5676|CA3417|CFL6|CaO19.6138|CaO19.13557 Predicted ORF in Assemblies 19, 20 and 21; similar to ferric reductase Fre10p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chrR 1592090 1594197 + orf19.6137 1592090 1594197 1 1592090 1594197 1592214 1594109 orf19.13556|IPF20978.1|IPF12777.2|Contig4-2201_0002|orf6.5677|CA3418|CaO19.6137|CaO19.13556|IPF12777 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1594061 1595179 - orf19.6136 1594061 1595179 1 1595179 1594061 1595113 1594184 orf19.13555|IPF20986.1|IPF12778.1|Contig4-2201_0003|orf6.5678|CA3419|CaO19.6136|MRPL4|CaO19.13555|IPF12778 Predicted ORF in Assemblies 19, 20 and 21; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1595306 1595948 + orf19.6135.1 1595306 1595948 1 1595306 1595948 1595398 1595688 SMX4 IPF21007.1|IPF12779.1|Contig4-2201_0004|CA3420 ORF Predicted by Annotation Working Group; flucytosine induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1595625 1596893 - orf19.6135 1595625 1596893 1 1596893 1595625 1596830 1595757 orf19.13554|IPF19782.1|IPF27803.1|Contig4-2201_0005|orf6.5679|CA3421|CaO19.6135|TID3|CaO19.13554|IPF19782 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1597409 1599878 + orf19.6134 1597409 1599878 1 1597409 1599878 1597414 1599867 orf19.13553|IPF17289.2|IPF27798.1|Contig4-2334_0004|Contig4-2334_0007|orf6.5680|CA3422|CaO19.6134|IPF17289 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1600077 1603008 + orf19.6133 1600077 1603008 1 1600077 1603008 1600261 1602981 PIF1 orf19.13552|IPF19672.2|IPF19673.2|Contig4-2334_0002|orf6.5114|orf6.5681|CA3002|CaO19.6133|IPF19673.1 Decreased transcription is observed upon fluphenazine treatment [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1603269 1603890 + orf19.6132 1603269 1603890 1 1603269 1603890 1603361 1603744 orf19.13551|IPF21000.1|IPF8841.2|Contig4-2334_0001|orf6.5113|CA3001|CaO19.13551|CaO19.6132|IPF8841 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1603758 1604799 - orf19.6131 1603758 1604799 1 1604799 1603758 1604756 1603824 KSR1 orf19.13550|IPF20987.1|IPF8842.2|Contig4-2655_0002|orf6.5112|CA3000|TSC10|CaO19.6131|CaO19.13550|TSC1.5 3-ketosphinganine reductase, catalyzes the second step in phytosphingosine synthesis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1604873 1605761 - orf19.6129 1604873 1605761 1 1605761 1604873 1605725 1604958 MRPL8 orf19.13548|IPF20988.1|IPF8844.2|Contig4-2655_0003|orf6.5110|CA2999|CaO19.6129|CaO19.13548 Predicted ribosomal protein of the mitochondrial 60S subunit [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1605916 1607694 - orf19.6127 1605916 1607694 1 1607694 1605916 1607579 1606104 LPD1 orf19.13546|IPF20981.1|IPF8847.2|Contig4-2655_0004|orf6.5108|CA2998|CaO19.6127|CaO19.13546 Putative dihydrolipoamide dehydrogenase; soluble protein in hyphae; antigenic during human oral infection and murine systemic infection; macrophage-induced protein [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1608048 1608122 - tk(uuu)2 1608048 1608122 1 1608122 1608048 tK(UUU)2.2 tRNA-Lys predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1609082 1610868 + orf19.6126 1609082 1610868 1 1609082 1610868 1609238 1610563 KGD2 orf19.13545|orf6.5107|IPF20983.1|IPF8851.2|Contig4-2655_0006|CA2997|CaO19.13545|CaO19.6126 Protein described as dihydrolipoamide S-succinyltransferase; transcriptionally regulated by iron; expression greater in high iron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1611848 1614433 + orf19.6124 1611848 1614433 1 1611848 1614433 1611848 1614199 ACE2 orf19.13543|IPF20973.1|IPF9108.2|Contig4-2916_0014|orf6.5105|CA2996|CaO19.6124|CaO19.13543|IPF9108 Putative transcription factor involved in regulation of morphogenesis; required for wild-type cell separation, adherence, biofilm formation, and virulence in mouse; mutant is hyperfilamentous; similar to S. cerevisiae Ace2p and Swi5p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chrR 1614264 1617443 - orf19.6121 1614264 1617443 1 1617443 1614264 1617244 1614527 MNL1 orf19.13540|IPF20971.1|IPF9113.2|Contig4-2916_0013|orf6.5102|CA2995|MSN2|CaO19.13540|CaO19.6121|IPF9113 Transcription factor that activates transcription of stress response genes via SLE (STRE-like) elements, required for adaptation to weak acid stress; activates a subset of the genes that are repressed by Nrg1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1617919 1618130 + ntar_1336 1617919 1618130 1 1617919 1618130 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1618004 1620553 - orf19.6119 1618004 1620553 1 1620553 1618004 1620230 1618215 orf19.13538|IPF20977.1|IPF9116.2|Contig4-2916_0011|orf6.5100|CA2994|CaO19.13538|CaO19.6119|IPF9116 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1620856 1621537 + orf19.6118 1620856 1621537 1 1620856 1621537 1620979 1621431 orf19.13537|IPF20994.1|IPF9118.1|Contig4-2916_0008|orf6.5099|CA2993|CaO19.6118|CaO19.13537|IPF9118 Putative protein of unknown function, transcription is positively regulated by Tbf1p; predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1622614 1623954 + orf19.6117 1622614 1623954 1 1622614 1623954 1622614 1623954 orf19.13536|IPF20054.1|IPF20982.1|IPF20123.1|Contig4-2916_0006|orf6.1016|orf6.5098|CA0262|orf19.1407|CaO19.13536|ZSP11|CaO19.6117|IPF20054 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=J scenario_last_exon=J] Ca21chrR 1624375 1625505 - orf19.6116 1624375 1625505 1 1625505 1624375 1625505 1624375 GLK4 orf19.13535|IPF8388.2|IPF20985.1|IPF18395.1|Contig4-1499_0003|Contig4-2916_0003|orf6.1017|orf6.5097|orf19.1408|CaO19.13535|CaO19.6116 Protein described as a glucokinase; decreased expression in hyphae compared to yeast-form cells [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chrR 1626335 1627021 + orf19.2620 1626335 1627021 1 1626335 1627021 1626335 1627021 orf19.10151|IPF24715.1|IPF19693.1|orf6.1411|CaO19.2620|CaO19.10151 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1627336 1627936 + orf19.2621 1627336 1627936 2 1627336|1627476 1627402|1627936 1627400 1627850 orf19.10152|IPF24717.1|IPF18977.1|orf6.1412|CA0469|IPF18977 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1627763 1628981 - orf19.2622 1627763 1628981 1 1628981 1627763 1628715 1628047 YPT31 orf19.10153|IPF24714.1|IPF12928.2|orf6.1413|CA0470|CaO19.2622|CaO19.10153|YPT32 Predicted ORF in Assemblies 19, 20 and 21 (see Locus History Note for Assembly 19 correction); mutation confers hypersensitivity to toxic ergosterol analog [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1629187 1632457 - orf19.2623 1629187 1632457 1 1632457 1629187 1631995 1629413 ECM22 orf19.10154|IPF24711.1|IPF12926.2|Contig4-2829_0014|orf6.1414|CA0471|ZCF12|CaO19.10154|CaO19.2623 Putative transcription factor with zinc cluster DNA-binding motif [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1634741 1636564 - orf19.2624 1634741 1636564 1 1636564 1634741 1636564 1634741 orf19.10155|IPF24712.1|IPF12767.2|Contig4-2829_0009|orf6.2650|CA1244|CaO19.10155|CaO19.2624|IPF12767 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21; decreased transcription is observed upon fluphenazine treatment or in an azole-resistant strain that overexpresses CDR1 and CDR2 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1637901 1638206 - orf19.2625 1637901 1638206 1 1638206 1637901 1638206 1637901 orf19.10156|IPF24719.1|IPF29046.1|Contig4-2829_0006|orf6.2649|CaO19.10156|CaO19.2625 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1639487 1642240 + orf19.729.1 1639487 1642240 1 1639487 1642240 1639487 1642126 RGD3 orf19.8349|orf19.10157|IPF24710.1|IPF20080.1|IPF26570.1|IPF20142.1|Contig4-2668_0002|Contig4-2829_0004|orf6.2648|orf6.5661|orf6.6013|CA3679|orf19.2626|RGD2|CaO19.730|CaO19.8349 Putative Rho GTPase activating protein; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chrR 1642484 1643548 + orf19.729 1642484 1643548 1 1642484 1643548 1642563 1643390 SHE3|orf19.8348|orf19.10158|IPF24713.1|IPF12772.1|IPF26582.1|IPF8395.2|orf6.6014|orf6.2647|CA3680|orf19.2627|SHE3-3|CaO19.8348|CaO19.729|IPF8395 Protein similar to S. cerevisiae She3p; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1643396 1647386 - orf19.728 1643396 1647386 1 1647386 1643396 1647308 1643445 TSC11 orf19.8347|IPF26588.1|IPF19787.1|orf6.6015|CA3681|CaO19.728|IPF19787 Protein similar to S. cerevisiae Tsc11p which is involved in sphingolipid biosynthesis; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chrR 1649673 1650496 + orf19.6293 1649673 1650496 1 1649673 1650496 1649799 1650401 orf19.13672|IPF20862.1|IPF9318.1|Contig4-1932_0001|orf6.5443|CA3230|EMP24|CaO19.13672|CaO19.6293 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1650935 1654409 + orf19.6291 1650935 1654409 1 1650935 1654409 1651031 1654324 orf19.13670|orf19.13671|IPF20865.1|IPF20843.1|IPF9320.1|IPF9324.1|Contig4-2283_0008|orf6.5441|orf6.5442|CA3229|orf19.6292|FUN30 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1654305 1654534 - ntar_1337 1654305 1654534 1 1654534 1654305 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1654552 1655046 - orf19.6288 1654552 1655046 1 1655046 1654552 1655046 1654552 orf19.13667|IPF20866.1|IPF9325.2|Contig4-2560_0001|orf6.5438|CA3228|CaO19.13667|CaO19.6288|IPF9325 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1655294 1656914 + orf19.6287 1655294 1656914 1 1655294 1656914 1655397 1656647 AAT21 orf19.13666|IPF20853.1|IPF9326.2|Contig4-2560_0002|orf6.5437|CA3227|CaO19.6287|AAT2|CaO19.13666 Predicted ORF in Assemblies 19, 20 and 21; Gcn4p-regulated; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1656839 1658039 - orf19.6286.2 1656839 1658039 2 1658039|1657494 1657925|1656839 1657927 1657249 RPS27 IPF9327.1|Contig4-2560_0004|CA3226|RPS27B Putative ribosomal protein; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1658357 1659738 - orf19.6286 1658357 1659738 1 1659738 1658357 1659187 1658591 orf19.13665|IPF20863.1|IPF9329.1|Contig4-2560_0006|orf6.5436|CA3225|CaO19.6286|IPF9329 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1658360 1658500 + ntar_1338 1658360 1658500 1 1658360 1658500 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1659419 1659811 + ntar_1339 1659419 1659811 1 1659419 1659811 1659419 1659658 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1659841 1660513 - ntar_1340 1659841 1660513 1 1660513 1659841 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1660711 1662859 + orf19.6285 1660711 1662859 2 1660711|1660896 1660735|1662859 1660910 1661902 GLC7 orf19.13664|orf6.5435|IPF20854.1|IPF18366.1|CA3224|CaO19.6285|CaO19.13664 Protein described as serine/threonine phosphatase; transcriptionally regulated by iron; expression greater in high iron; intron in 5'-UTR [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1662675 1663962 - orf19.6284 1662675 1663962 1 1663962 1662675 1663894 1662977 orf19.13663|IPF18880.2|IPF20855.1|IPF17133.2|Contig4-1438_0001|orf6.1871|orf6.5434|CA3223|orf19.3484|SRP102|CaO19.13663|CaO19.6284 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1664125 1664987 + orf19.6283 1664125 1664987 1 1664125 1664987 1664160 1664948 orf19.13662|IPF15883.2|IPF20857.1|IPF17135.1|Contig4-1438_0003|Contig4-2574_0001|orf6.1872|orf6.5433|CA3222|orf19.3485|NFU2|CaO19.6283|CaO19.13662|IPF15883 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1665020 1667565 - orf19.6282 1665020 1667565 1 1667565 1665020 1667565 1665118 orf19.13661|IPF15880.2|IPF20858.1|IPF17137.2|Contig4-2574_0003|Contig4-2574_0004|Contig4-2574_0005|orf6.5432|orf6.1873|CA0754|orf19.3486|CaO19.6282|CaO19.13661 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chrR 1669566 1670703 + orf19.3487 1669566 1670703 1 1669566 1670703 1669743 1670078 IPF14861.2|CA0755|CaO19.3487|IPF14861|orf6.1874 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1670548 1670968 - ntar_1341 1670548 1670968 1 1670968 1670548 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1670965 1671222 - ntar_1342 1670965 1671222 1 1671222 1670965 1671114 1670965 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1671057 1672508 + orf19.1985 1671057 1672508 1 1671057 1672508 1671193 1672404 IPF19000.1|IPF14674.2|IPF14859.2|Contig4-2574_0011|orf6.1283|orf6.1875|orf6.1284|CA0756|orf19.1984|orf19.3488 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1671508 1671702 - ntar_1343 1671508 1671702 1 1671702 1671508 1671702 1671565 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1671782 1672240 - ntar_1344 1671782 1672240 1 1672240 1671782 1672240 1672040 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1672040 1672483 - ntar_1345 1672040 1672483 1 1672483 1672040 1672240 1672040 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1672586 1674100 + orf19.1986 1672586 1674100 1 1672586 1674100 1672586 1673827 ARO2 IPF14673.2|IPF14858.2|Contig4-2549_0012|orf6.1285|orf6.1876|CA0398|orf19.3489|ARO22|CaO19.1986 Putative chorismate synthase; fungal-specific (no human or murine homolog); protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chrR 1673865 1675832 - orf19.1988 1673865 1675832 1 1675832 1673865 1675738 1673999 CDC45 IPF14671.2|IPF19695.1|Contig4-2549_0008|Contig4-2549_0010|Contig4-2549_0011|orf6.1287|orf6.1439|CA0399|orf19.2634|CaO19.1988 Protein described as a DNA replication initiation factor; transcriptionally regulated by interaction with macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1677282 1679224 + orf19.2633 1677282 1679224 1 1677282 1679224 1677431 1679209 HGT14 IPF8610.1|Contig4-2549_0002|orf6.1438|CA0480|QUP1|CaO19.2633|IPF8610 Putative glucose transporter of the major facilitator superfamily; the C. albicans glucose transporter family comprises 20 members; 12 probable membrane-spanning segments; expressed in rich medium with 2% glucose [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1678529 1679184 - ntar_1346 1678529 1679184 1 1679184 1678529 1679184 1678936 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1679502 1680076 + orf19.2633.1 1679502 1680076 1 1679502 1680076 1679746 1679940 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1679893 1681988 - orf19.3704 1679893 1681988 1 1681988 1679893 1681888 1680068 orf19.11188|IPF18971.2|IPF23554.1|IPF8614.2|Contig4-1425_0002|orf6.2153|orf6.1437|CA0939|orf19.2632|CaO19.3704|DBP6|CaO19.11188 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1682054 1682628 + orf19.3704.1 1682054 1682628 1 1682054 1682628 1682156 1682431 IPF23568.1|IPF8616.1|Contig4-1425_0003|Contig4-2552_0007|CA0940|IPF8616 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1682476 1684043 - orf19.3705 1682476 1684043 1 1684043 1682476 1683895 1682492 PTC6 orf19.11189|IPF19973.2|IPF8617.1|Contig4-2552_0005|Contig4-2552_0006|orf6.2154|orf6.5302|CA0941|CaO19.3705|IPF8617 Putative protein phosphatase of the Type 2C-related family (serine/threonine-specific), similar to S. cerevisiae Ptc6p; mutant shows virulence defect [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1684582 1686707 + orf19.3706 1684582 1686707 1 1684582 1686707 1684739 1686577 orf19.11191|IPF18381.1|IPF8619.2|Contig4-2552_0003|orf6.2155|orf6.5303|orf6.5304|CA0942|CaO19.3706|IPF8619 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1686318 1686448 - ntar_1347 1686318 1686448 1 1686448 1686318 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1686909 1688403 - orf19.3707 1686909 1688403 1 1688403 1686909 1688203 1687007 YHB1 orf19.11192|orf6.2156|IPF23556.1|IPF8621.2|Contig4-2552_0002|orf6.5305|CA0943|CaO19.3707 Nitric oxide dioxygenase, acts in nitric oxide scavenging/detoxification; role in virulence in mouse; transcription activated by NO, macrophage interaction; hyphal downregulated; mRNA binds to She3p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1691563 1692242 - ntar_1348 1691563 1692242 1 1692242 1691563 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1692494 1693826 - ntar_1349 1692494 1693826 1 1693826 1692494 1693560 1693363 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1692725 1693921 + orf19.3708 1692725 1693921 1 1692725 1693921 1692725 1693921 SAP2 orf19.11193|PRA|CAP|PRA11|SAP2x|PEP|PEP11|IPF23558.1|IPF9220.2|Contig4-2800_0001|orf6.5306|CA3138|CaO19.3708|CaO19.11193 Major secreted aspartyl proteinase; roles in use of protein as nitrogen source, virulence in mouse, rat, guinea pig, human vaginal epithelium; immunoprotective; allele-specific function; regulated by growth, albumin, drugs, white cell-type [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1694089 1694443 - ntar_1350 1694089 1694443 1 1694443 1694089 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1696893 1698294 + orf19.3710 1696893 1698294 1 1696893 1698294 1696963 1698165 YHB5 orf19.11195|IPF23557.1|IPF9216.2|YHB3|Contig4-2800_0005|orf6.5308|CA3139|CaO19.11195|YHB2|CaO19.3710 Protein related to flavohemoglobins; not required for wild-type nitric oxide resistance; has predicted globin, FAD-binding, and NAD(P)-binding domains but lacks some conserved residues of flavohemoglobins; mRNA detected; filament induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1700050 1702239 + orf19.3711 1700050 1702239 1 1700050 1702239 1700050 1702239 orf19.11196|IPF23551.1|IPF9214.2|Contig4-2800_0007|orf6.5309|CA3140|CaO19.11196|PHH2|CaO19.3711|IPF9214 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1702585 1703464 - orf19.3712 1702585 1703464 1 1703464 1702585 1703464 1703015 orf19.11197|IPF23561.1|IPF9213.2|Contig4-2800_0009|orf6.5310|CA3141|CaO19.11197|CaO19.3712|IPF9211.3f Predicted ORF in Assemblies 19, 20 and 21; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1703561 1704151 - orf19.3713 1703561 1704151 1 1704151 1703561 1704151 1703561 orf19.11198|IPF23560.1|IPF9211.2|orf6.5311|CA3142|CaO19.3713|CaO19.11198|IPF9211.5f Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction); transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1706751 1708832 + orf19.3714 1706751 1708832 1 1706751 1708832 1706954 1708801 orf19.11199|IPF23552.1|IPF8295.2|Contig4-2908_0005|orf6.5312|CA3143|CaO19.3714|CaO19.11199|IPF8295 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1708861 1709828 - orf19.3715 1708861 1709828 1 1709828 1708861 1709657 1708914 ASF1 orf19.11200|IPF23559.1|IPF8293.2|Contig4-2908_0006|orf6.5313|CA3144|CaO19.11200|CaO19.3715 Protein likely to be essential for growth, based on an insertional mutagenesis strategy; similar to S. cerevisiae Asf1p, which is a chromatin assembly complex component [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1712520 1713611 + orf19.612 1712520 1713611 1 1712520 1713611 1712520 1713512 orf19.8245|orf19.11201|IPF23564.1|IPF18378.1|IPF26713.1|IPF8287.2|Contig4-2908_0009|orf6.2976|orf6.5314|CA1457|orf19.3716|CaO19.8245|CaO19.612|IPF8287 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chrR 1713688 1713758 - tg(gcc)1 1713688 1713758 1 1713758 1713688 tG(GCC)1.2 tRNA-Gly predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1717779 1718282 - ntar_1351 1717779 1718282 1 1718282 1717779 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1718960 1719206 - ntar_1352 1718960 1719206 1 1719206 1718960 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1718975 1719571 + ntar_1353 1718975 1719571 1 1718975 1719571 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1722450 1725631 + orf19.610 1722450 1725631 1 1722450 1725631 1723589 1725166 EFG1 IPF3577.2|IPF3575.2|Contig4-2215_0003|orf6.2978|orf6.4821|CA2787|orf19.8243 Transcriptional repressor; required for white-phase cell type; hyphal growth, metabolism, cell-wall gene regulator; roles in adhesion, virulence; Cph1p and Efg1p have role in host cytokine response; bHLH; binds E-box; T206 phosphorylated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1725648 1725983 - orf19.609 1725648 1725983 1 1725983 1725648 1725983 1725648 IPF29770.1|orf6.2979|CaO19.609 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21; transcription is specific to white cell type [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1726017 1729478 - orf19.607 1726017 1729478 1 1729478 1726017 1729384 1726217 orf19.8240|IPF3569.2|IPF29784.1|Contig4-2930_0001|orf6.2980|orf6.4824|CA2788|RAD26|CaO19.607 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1729633 1729913 - ntar_1354 1729633 1729913 1 1729913 1729633 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1730957 1733423 + orf19.606 1730957 1733423 1 1730957 1733423 1731302 1733218 orf19.8239|IPF26699.1|IPF3567.1|Contig4-2930_0007|orf6.4825|CA2789|CaO19.606|CaO19.8239|IPF3567 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1733930 1734244 - orf19.605 1733930 1734244 1 1734244 1733930 1734244 1733930 orf19.8238|IPF26740.1|IPF3564.1|Contig4-2930_0009|orf6.4826|CaO19.605|CaO19.8238 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1734248 1735666 - ntar_1355 1734248 1735666 1 1735666 1734248 1735635 1735237 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1734493 1736622 + orf19.604 1734493 1736622 1 1734493 1736622 1734493 1736622 orf19.8237|IPF26694.1|IPF3562.2|Contig4-2930_0011|orf6.4827|CA2790|CaO19.8237|PHH1|CaO19.604|IPF3562 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1735834 1736562 - ntar_1356 1735834 1736562 1 1736562 1735834 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1736970 1737978 + orf19.603 1736970 1737978 1 1736970 1737978 1737038 1737889 IMP4 orf19.8236|IPF26716.1|IPF3560.2|Contig4-2930_0013|orf6.4828|CA2791|CaO19.603|CaO19.8236 Predicted ORF in Assemblies 19, 20 and 21; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1737827 1741618 - orf19.600 1737827 1741618 2 1741618|1741199 1741349|1737827 1741134 1737964 TRK1 orf19.8233|orf19.8235|IPF3557.2|IPF19076.2|Contig4-2930_0014|Contig4-2930_0017|orf6.4829|orf6.4831|orf6.993|CA2793|CA2792|orf19.602|TRK1.5f Potassium transporter; mediates K+ and Cl- influx; role in sensitivity to cationic antimicrobial peptides, not via direct peptide uptake, but possibly related to membrane permeability; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1741699 1742709 + ntar_1357 1741699 1742709 1 1741699 1742709 1742274 1742477 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1742933 1743292 - orf19.599 1742933 1743292 1 1743292 1742933 1743292 1742933 orf19.8232|IPF26728.1|IPF3553.2|Contig4-2930_0019|orf6.4832|orf6.992|CaO19.599 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1748791 1749168 - orf19.598 1748791 1749168 1 1749168 1748791 1749168 1748791 orf19.8230|IPF26736.1|IPF29777.1|Contig4-2132_0004|orf6.5682|CaO19.8230|CaO19.598 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1749581 1751563 - orf19.597 1749581 1751563 1 1751563 1749581 1751403 1749721 orf19.8229|IPF26700.1|IPF3549.1|Contig4-2132_0002|orf6.5683|CA3423|AAT21|CaO19.597|IPF3549 Predicted ORF in Assemblies 19, 20 and 21; Gcn4p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1752009 1752798 + orf19.596.2 1752009 1752798 2 1752009|1752265 1752179|1752798 1752120 1752438 Predicted ORF in Assembly 20 and 21; gene has intron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1752519 1753026 - orf19.596.1 1752519 1753026 1 1753026 1752519 1753003 1752824 NOP10 IPF26697.1|IPF3544.2|CA3424 ORF Predicted by Annotation Working Group; flucytosine induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1753195 1755579 - orf19.593 1753195 1755579 1 1755579 1753195 1755545 1753224 FGR32 orf19.8225|IPF26688.1|IPF11873.2|Contig4-2431_0002|orf6.5687|CA3425|CaO19.593|SWA2|CaO19.8225|IPF11873 Protein described as similar to S. cerevisiae Swa2p; induced upon adherence to polystyrene; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1755720 1757134 + orf19.592 1755720 1757134 1 1755720 1757134 1755810 1756997 orf19.8224|IPF26710.1|IPF11869.2|Contig4-2431_0001|orf6.5688|CA3426|CaO19.8224|CaO19.592|IPF11869 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1756869 1758030 - orf19.590 1756869 1758030 1 1758030 1756869 1757970 1757071 orf19.8222|IPF26715.1|IPF11865.1|orf6.5690|CA3427|CaO19.8222|CaO19.590|IPF11865 Predicted ORF in Assemblies 19, 20 and 21; decreased expression observed in an ssr1 homozygous null mutant; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1758246 1759409 - orf19.589 1758246 1759409 1 1759409 1758246 1759084 1758434 VPS21 orf19.8221|orf19.13721|IPF11863.1|IPF20756.1|IPF18324.1|Contig4-1955_0002|orf6.5691|orf6.5816|CA3428|CA3531|orf19.6364|VPS211|CaO19.589|CaO19.8221|CaO19.6364|VPS212|CaO19.13721 Late endosomal Rab small monomeric GTPase involved in transport of endocytosed proteins to the vacuole; involved in filamentous growth and virulence [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1760126 1761356 + orf19.6365 1760126 1761356 1 1760126 1761356 1760180 1761298 PTP1 orf19.13722|IPF20741.1|IPF13448.2|orf6.5817|CA3532|CaO19.6365|CaO19.13722|IPF13448 Protein not essential for viability; similar to S. cerevisiae Ptp1p, which is a protein tyrosine phosphatase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1761415 1762189 - ntar_1358 1761415 1762189 1 1762189 1761415 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1761466 1762224 + orf19.6366 1761466 1762224 1 1761466 1762224 1761466 1762224 orf19.13723|IPF20753.1|IPF13450.2|orf6.5818|CA3533|CaO19.6366|CaO19.13723|IPF13450 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1762503 1764539 + orf19.6367 1762503 1764539 1 1762503 1764539 1762547 1764388 SSB1 orf19.13724|HS75|IPF20722.1|IPF13454.2|orf6.5819|CA3534|CaO19.6367|CaO19.13724 Putative heat shock protein; SSB subfamily of the HSP70 family; mRNA in yeast-form cells, germ tubes; at surface of yeast-form cells, but not hyphae; soluble in hyphae; antigenic in human, mouse systemic infection; macrophage, GCN-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1764532 1765972 - orf19.6369 1764532 1765972 1 1765972 1764532 1765972 1764569 orf19.13726|IPF20732.1|IPF13458.2|orf6.5821|CA3535|CaO19.6369|CaO19.13726|IPF13458 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chrR 1766025 1768240 + orf19.6371 1766025 1768240 1 1766025 1768240 1766062 1767336 orf19.13728|IPF20736.1|IPF5414.2|orf6.5823|CA3536|CaO19.13728|CaO19.6371|IPF5414 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1767218 1770249 - orf19.6373 1767218 1770249 1 1770249 1767218 1770096 1767349 orf19.13730|IPF20703.1|IPF5418.2|orf6.5825|CA3537|CaO19.6373|DCP2|CaO19.13730|PSU1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1770183 1771517 + orf19.6374 1770183 1771517 1 1770183 1771517 1770183 1771313 orf19.13731|IPF20740.1|IPF5420.1|orf6.5826|CA3538|CaO19.13731|ATP10|CaO19.6374 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chrR 1771616 1772001 - ntar_1359 1771616 1772001 1 1772001 1771616 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1771901 1773053 + orf19.6375 1771901 1773053 1 1771901 1773053 1772309 1772668 RPS20 orf19.13732|IPF20783.1|IPF5422.2|orf6.5827|CA3539|CaO19.6375|RPS22|CaO19.13732 Putative ribosomal protein; genes encoding cytoplasmic ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage; transcription is positively regulated by Tbf1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1773491 1775722 + orf19.6376 1773491 1775722 1 1773491 1775722 1773751 1775493 PTC5 orf19.13733|IPF20726.1|IPF5424.2|orf6.5828|CA3540|CaO19.13733|CaO19.6376 Putative protein phosphatase of the Type 2C-related family (serine/threonine-specific), similar to S. cerevisiae Ptc5p; mutant shows virulence defect [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1775734 1777086 - orf19.6377 1775734 1777086 1 1777086 1775734 1777064 1775961 orf19.13734|IPF20742.1|IPF5425.1|orf6.5829|CA3541|PPM1|CaO19.6377|CaO19.13734|IPF5425 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1777100 1778042 - orf19.6378 1777100 1778042 1 1778042 1777100 1777998 1777201 TRM9 orf19.13735|IPF20749.1|IPF5426.1|orf6.5830|CA3542|CaO19.13735|CaO19.6378|IPF5426 Protein repressed during the mating process [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1778118 1778894 + orf19.6379 1778118 1778894 1 1778118 1778894 1778168 1778626 orf19.13736|IPF20765.1|IPF5428.2|orf6.5831|CA3543|CaO19.6379|GPI17|CaO19.13736|IPF5428 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1778689 1783318 - orf19.6382 1778689 1783318 1 1783318 1778689 1783213 1778741 orf19.13739|orf19.13740|IPF19490.2|IPF20755.1|IPF12646.2|IPF12648.1|Contig4-2922_0014|orf6.11|orf6.5834|orf6.5835|CA3544|CA3545|orf19.6383|BPT1.3f Putative MRP/CFTR-subfamily ABC transporter; member of multidrug resistance-associated protein (MRP) subfamily of ABC family; similar to S. cerevisiae Bpt1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1783477 1785929 - orf19.6385 1783477 1785929 1 1785929 1783477 1785893 1783560 ACO1 orf19.13742|orf6.7870|ACON|IPF18134.2|IPF12652.2|Contig4-2922_0012|orf6.5837|CA3546|CaO19.13742|CaO19.6385 Protein described as aconitase; Gcn4p-regulated; amino acid starvation (3-AT treatment), amphotericin B, phagocytosis, farnesol induced; fluconazole-downregulated; expression greater in high iron; antigenic in human or murine infection [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1787033 1787118 - tk(uuu)3 1787033 1787118 2 1787118|1787068 1787080|1787033 tK(UUU)3.2 tRNA-Lys predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1787791 1787865 - tk(uuu)4 1787791 1787865 1 1787865 1787791 tK(UUU)4.2 tRNA-Lys predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1788498 1788670 - ntar_1360 1788498 1788670 1 1788670 1788498 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1788796 1789054 + tk(uuu)5 1788796 1789054 1 1788796 1789054 1788920 1789042 tK(UUU)5.2 tRNA-Lys predicted by tRNAscan-SE [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=D scenario_last_exon=D] Ca21chrR 1788960 1791743 - orf19.6387 1788960 1791743 1 1791743 1788960 1791743 1789044 HSP104 orf19.13747|IPF5137.2|IPF27720.1|IPF18323.2|Contig4-2922_0008|orf6.7865|orf6.5839|CA6306|CA5135|orf19.6389|HSP104.3f Functional homolog of S. cerevisiae Hsp104p; has chaperone and prion propagation activity in S. cerevisiae; guanidine-insensitive; heat shock/stress induced; downregulated in biofilm upon treatment with farnesol; no human or murine homolog [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1791747 1792049 - orf19.6390 1791747 1792049 1 1792049 1791747 1792049 1791747 orf19.13748|orf6.7864|CaO19.6390|CaO19.13748 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1792440 1793360 + orf19.6391 1792440 1793360 1 1792440 1793360 1792440 1793360 orf19.13749|IPF20748.1|IPF5131.1|IPF5131|Contig4-2922_0006|orf6.7863|CA5134|CaO19.13749|CaO19.6391 Increased transcription is observed in an azole-resistant strain that overexpresses MDR1 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1793525 1794705 + orf19.6392 1793525 1794705 1 1793525 1794705 1793525 1794562 orf19.13750|IPF20745.1|IPF5129.1|Contig4-2922_0002|orf6.7862|CA5133|CaO19.6392|CaO19.13750|IPF5129 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1794787 1796474 + orf19.6393 1794787 1796474 1 1794787 1796474 1794831 1796081 orf19.13751|IPF20739.1|IPF5128.2|Contig4-2922_0001|orf6.7861|CA5132|GTS1|CaO19.13751|CaO19.6393 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1796331 1800779 - orf19.6396 1796331 1800779 1 1800779 1796331 1800743 1796583 orf19.13754|orf6.7858|IPF20776.1|IPF5124.1|CA5131|IPF5124|CaO19.6396|CaO19.13754 Putative patatin-like phospholipase; similar to S. cerevisiae Yml059p, which is predicted to be a membrane protein: antigenic during human oral infection [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1801066 1802223 - orf19.6398 1801066 1802223 1 1802223 1801066 1802223 1801066 orf19.13756|IPF5121.1|IPF19416.2|Contig4-2839_0001|orf6.163|orf6.7856|CA5130|TCD2|CaO19.6398|IFH2 Predicted ORF in Assemblies 19, 20 and 21; induced by nitric oxide [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1802718 1803816 + orf19.6399 1802718 1803816 1 1802718 1803816 1802855 1803757 ATS1 orf19.13757|IPF5119.1|IPF17871.3|Contig4-2839_0005|orf6.164|orf6.7855|CA5129|CaO19.6399 Induced upon adherence to polystyrene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1803323 1803885 - ntar_1361 1803323 1803885 1 1803885 1803323 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1804107 1804979 + orf19.6400 1804107 1804979 1 1804107 1804979 1804166 1804831 orf19.13758|IPF5118.1|IPF17872.3|Contig4-2839_0006|orf6.165|orf6.7854|CA5128|CaO19.6400|CaO19.13758|IPF5118 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1805595 1807077 + orf19.6402 1805595 1807077 1 1805595 1807077 1805750 1806949 CYS3 orf19.13760|IPF20738.1|IPF5115.2|Contig4-2839_0007|orf6.7852|CA5127|CaO19.13760|CaO19.6402 Predicted enzyme of sulfur amino acid biosynthesis; upregulated in biofilm; alkaline upregulated; amphotericin B induced; possibly adherence-induced; induced by heavy metal (cadmium) stress, oxidative stress (via Cap1p); Hog1p regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1807305 1808729 + orf19.6403 1807305 1808729 1 1807305 1808729 1807379 1808623 orf19.13761|IPF20735.1|IPF5113.2|Contig4-2839_0009|orf6.7851|CA5126|CaO19.6403|CaO19.13761|SLS1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1808535 1809537 - orf19.6403.1 1808535 1809537 2 1809537|1809145 1809491|1808535 1809491 1808820 RPP2A RP2A|CARP2A|RPP2|IPF20786.1|IPF5111.2|Contig4-2839_0010|Contig4-2839_0011|CA5125 Conserved acidic ribosomal protein, likely involved in regulation of translation elongation; interacts with Rpp1Bp; one of four similar ribosomal proteins (Rpp1Ap, Rpp1Bp, Rpp2Ap, Rpp2Bp); CUG start codon; upstream uORFs; Tbf1p-activated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1809736 1809951 + ntar_1362 1809736 1809951 1 1809736 1809951 1809736 1809867 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1810205 1812049 + orf19.6404 1810205 1812049 1 1810205 1812049 1810357 1811814 GSH2 orf19.13762|orf6.7850|IPF20730.1|IPF1304.2|Contig4-3073_0031|CA5124|CaO19.13762|CaO19.6404 Protein described as glutathione synthase; transcriptionally regulated by iron; expression greater in high iron; heavy metal (cadmium) stress-induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1811878 1812830 - orf19.6405 1811878 1812830 2 1812830|1812717 1812774|1811878 1812830 1811878 orf19.13763|IPF20751.1|IPF1306.1|Contig4-3073_0030|orf6.7849|CA5123|CaO19.13763|CaO19.6405|IPF1306 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21; decreased transcription is observed in an azole-resistant strain that overexpresses MDR1 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1813285 1813370 + ti(aau)5 1813285 1813370 2 1813285|1813335 1813322|1813370 tI(AAU)5.2 tRNA-Ile predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1813441 1814180 - orf19.6406 1813441 1814180 1 1814180 1813441 1814138 1813770 orf19.13764|IPF20780.1|IPF1308.1|Contig4-3073_0029|orf6.7848|CA5122|MRPS13|CaO19.13764|CaO19.6406|IPF1308 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1814329 1815941 + orf19.6407 1814329 1815941 1 1814329 1815941 1814387 1815739 orf19.13765|IPF20731.1|IPF1310.2|Contig4-3073_0027|Contig4-3073_0028|orf6.7847|CA5121|CaO19.13765|CaO19.6407|IPF1310 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1816495 1818626 + orf19.6408 1816495 1818626 1 1816495 1818626 1816749 1818368 orf19.13766|IPF20728.1|IPF1317.2|Contig4-3073_0023|orf6.7846|CA5120|CaO19.13766|CaO19.6408|YDJ1 Predicted ORF in Assemblies 19, 20 and 21; induced during planktonic growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1818694 1821567 + orf19.6411 1818694 1821567 1 1818694 1821567 1818771 1821443 orf19.13769|IPF20702.1|IPF1320.1|Contig4-3073_0022|orf6.7843|YLR386W|CA5119|VAC14|CaO19.13769|CaO19.6411|IPF1320 Predicted ORF in Assemblies 19, 20 and 21; similar to S. cerevisiae Ylr386wp; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1821581 1823632 + orf19.6413 1821581 1823632 1 1821581 1823632 1821704 1823557 orf19.13771|IPF20720.1|IPF1321.1|Contig4-3073_0021|orf6.7841|CA5118|CaO19.13771|CaO19.6413|IPF1321 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chrR 1823553 1825767 - orf19.6414 1823553 1825767 1 1825767 1823553 1825586 1823664 orf19.13772|IPF20718.1|IPF1323.2|Contig4-3073_0020|orf6.7840|CA5117|CaO19.6414|CaO19.13772|IPF1323 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1826823 1828161 + orf19.6414.3 1826823 1828161 2 1826823|1827393 1827005|1828161 1826988 1827860 TPM2 IPF20770.1|IPF1325.1|Contig4-3073_0016|CA5116|TPM2.3 Protein described as tropomyosin isoform 2; regulated by Gcn4p; repressed in response to amino acid starvation (3-aminotriazole treatment); macrophage-induced protein; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1828643 1830200 + orf19.6416 1828643 1830200 1 1828643 1830200 1828758 1830155 orf19.13774|IPF20733.1|IPF1331.1|Contig4-3073_0014|orf6.7838|CA5115|CaO19.6416|CaO19.13774|IPF1331 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1830382 1831040 + ntar_1363 1830382 1831040 1 1830382 1831040 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1830821 1832066 - orf19.6415.1 1830821 1832066 2 1832066|1831384 1831912|1830821 1831363 1831193 IPF20724.1|IPF27718.1 ORF Predicted by Annotation Working Group; intron in 5'-UTR [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1832372 1835020 + orf19.6417 1832372 1835020 1 1832372 1835020 1832468 1834996 TSR1 orf19.13775|IPF20707.1|IPF1334.1|Contig4-3073_0011|orf6.7837|CA5114|tsr1|CaO19.13775|CaO19.6417|IPF1334 Predicted ORF in Assemblies 19, 20 and 21; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1835157 1836610 + orf19.6418 1835157 1836610 1 1835157 1836610 1835222 1836484 orf19.13776|IPF20737.1|IPF20026.1|Contig4-3073_0009|Contig4-3073_0010|orf6.7836|CA5113|CaO19.13776|CaO19.6418|IPF20026 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1838894 1840448 + orf19.6420 1838894 1840448 1 1838894 1840448 1838917 1840287 PGA13 orf19.13778|IPF20734.1|IPF1341.1|Contig4-3073_0004|orf6.7834|CA5112|CaO19.6420|CaO19.13778|IPF1341 Putative GPI-anchored protein; described as similar to mucins; induced during cell wall regeneration, and during core caspofungin response; regulated by Tsa1p, Tsa1Bp in minimal media at 37 deg and by Cyr1p, Nrg1p, Tup1p, Rlm1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1840504 1841369 - orf19.6419.1 1840504 1841369 2 1841369|1841144 1841233|1840504 1841324 1840904 Predicted ORF in Assembly 20 and 21; gene has intron [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1841913 1842027 - tl(caa)4 1841913 1842027 2 1842027|1841956 1841989|1841913 tL(CAA)4.2 tRNA-Leu predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1842149 1844866 - orf19.6422 1842149 1844866 1 1844866 1842149 1844840 1842333 SSY5 orf19.13780|IPF20706.1|IPF1345.1|Contig4-3073_0034|orf6.7832|CA5111|CaO19.13780|CaO19.6422 Protein similar to S. cerevisiae Ssy5p, which is a component of a complex that senses external amino acids [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1845289 1846491 + orf19.6423 1845289 1846491 1 1845289 1846491 1845375 1846403 orf19.13781|IPF20744.1|IPF1347.1|Contig4-3074_0047|Contig4-3074_0048|orf6.7831|CA5110|FBP26|CaO19.6423|CaO19.13781 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1846394 1847151 - orf19.6424 1846394 1847151 1 1847151 1846394 1847151 1846492 orf19.13782|IPF20759.1|IPF1348.1|Contig4-3074_0046|orf6.7830|CA5109|UBC9|CaO19.13782|CaO19.6424 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chrR 1847136 1851113 + orf19.6425 1847136 1851113 1 1847136 1851113 1847221 1850958 orf19.13783|IPF20784.1|IPF1354.1|Contig4-3074_0039|Contig4-3074_0041|Contig4-3074_0043|orf6.7829|CA5108|CaO19.6425|SKI2|CaO19.13783 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1850824 1851787 - orf19.6431 1850824 1851787 1 1851787 1850824 1851753 1850953 orf19.13789|IPF20752.1|IPF1358.1|Contig4-3074_0037|orf6.7823|CA5107|CaO19.6431|CaO19.13789|IPF1358 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1851866 1854325 + orf19.6432 1851866 1854325 1 1851866 1854325 1851913 1854213 orf19.13790|IPF20711.1|IPF1361.1|Contig4-3074_0036|orf6.7822|CA5106|CaO19.13790|AFG2|CaO19.6432 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1854210 1855885 - orf19.6434 1854210 1855885 1 1855885 1854210 1855300 1854302 orf19.13792|IPF20746.1|IPF1363.1|Contig4-3074_0034|orf6.7820|CA5105|CaO19.13792|PEX19|CaO19.6434 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1855543 1855783 + ntar_1364 1855543 1855783 1 1855543 1855783 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1856017 1856630 + orf19.6435 1856017 1856630 1 1856017 1856630 1856108 1856506 orf19.13793|IPF20774.1|IPF1364.1|Contig4-3074_0033|orf6.7819|CA5104|CaO19.6435|CaO19.13793|IPF1364 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1856463 1857682 - orf19.6436 1856463 1857682 1 1857682 1856463 1857646 1856582 orf19.13794|IPF20743.1|IPF1367.1|Contig4-3074_0032|orf6.7818|CA5103|CaO19.6436|CaO19.13794|IPF1367 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1857737 1859668 + orf19.6437 1857737 1859668 1 1857737 1859668 1857783 1859531 CDC23 orf19.13795|IPF20725.1|IPF1368.2|Contig4-3074_0028|Contig4-3074_0029|orf6.7817|CA5102|CaO19.13795|CaO19.6437 Similar to anaphase-promoting complex component; possibly transcriptionally regulated by Tac1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1859557 1861615 - orf19.6438 1859557 1861615 1 1861615 1859557 1861426 1859663 orf19.13796|IPF20723.1|IPF1370.2|Contig4-3074_0027|orf6.7816|CA5101|CaO19.6438|LCB1|CaO19.13796 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1861770 1864247 - orf19.6440 1861770 1864247 1 1864247 1861770 1863991 1861847 orf19.13798|IPF20716.1|IPF1372.2|Contig4-3074_0025|orf6.7814|CA5100|CaO19.6440|CaO19.13798|IPF1372 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1864419 1871805 + orf19.6442 1864419 1871805 1 1864419 1871805 1864470 1871720 PRP8 orf19.13800|IPF20757.1|IPF1378.2|Contig4-3074_0021|Contig4-3074_0023|Contig4-3074_0024|orf6.7812|CA5099|CaO19.13800|CaO19.6442 Protein similar to S. cerevisiae Prp8p; transcription is repressed in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1871700 1872578 - orf19.6443 1871700 1872578 1 1872578 1871700 1872540 1871737 orf19.13801|IPF20750.1|IPF1380.2|Contig4-3074_0019|orf6.7811|CA5098|DCI1|CaO19.6443|CaO19.13801|IPF1380 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1872641 1874827 - orf19.6444 1872641 1874827 1 1874827 1872641 1874827 1872680 orf19.13802|IPF20712.1|IPF1382.2|Contig4-3074_0015|Contig4-3074_0017|orf6.7810|CA5097|CaO19.13802|CaO19.6444|IPF1382 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1874876 1875949 - orf19.6445 1874876 1875949 1 1875949 1874876 1875847 1874930 ECI1 orf19.13803|IPF20747.1|IPF1384.1|Contig4-3074_0014|orf6.7809|CA5096|CaO19.6445|CaO19.13803|IPF1384 Protein similar to S. cerevisiae Eci1p, which is involved in fatty acid oxidation; transposon mutation affects filamentous growth; expression is regulated upon white-opaque switching [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1875993 1876640 - orf19.6447 1875993 1876640 1 1876640 1875993 1876622 1876083 ARF1 orf19.13805|ARF|IPF20763.1|IPF1386.1|Contig4-3074_0012|orf6.7807|CA5095|CaO19.6447|CaO19.13805|ARF21 ADP-ribosylation factor, probable GTPase involved in intracellular transport; one of several C. albicans ADP-ribosylation factors; N-myristoylprotein; substrate of Nmt1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1876813 1879043 + orf19.6448 1876813 1879043 1 1876813 1879043 1876856 1879009 orf19.13806|IPF20715.1|IPF1387.2|Contig4-3074_0009|Contig4-3074_0010|orf6.7806|CA5094|CaO19.13806|CaO19.6448|IPF1387 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1879205 1881064 + orf19.6449 1879205 1881064 1 1879205 1881064 1879205 1881064 orf19.13807|IPF20721.1|IPF1390.2|Contig4-3074_0008|orf6.7805|CA5093|CaO19.6449|YFW4|CaO19.13807|IPF1390 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=E scenario_last_exon=E] Ca21chrR 1881055 1881148 + te(uuc)7 1881055 1881148 2 1881055|1881114 1881091|1881148 tE(UUC)7.2 tRNA-Glu predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1881317 1881532 + ntar_1365 1881317 1881532 1 1881317 1881532 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1881876 1882556 + orf19.6450 1881876 1882556 1 1881876 1882556 1881876 1882556 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1882557 1882789 - tg(gcc)6 1882557 1882789 1 1882789 1882557 tG(GCC)6.2 tRNA-Gly predicted by tRNAscan-SE [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chrR 1884908 1885214 - ntar_1366 1884908 1885214 1 1885214 1884908 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1885119 1885482 + ntar_1367 1885119 1885482 1 1885119 1885482 1885198 1885416 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1885488 1886507 - ntar_1368 1885488 1886507 1 1886507 1885488 1885923 1885777 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1888541 1889205 - rdn5 1888541 1889205 1 1889205 1888541 1888727 1888542 RDN5 5S ribosomal RNA; component of the large (60S) ribosomal subunit; encoded in about 55 copies of the rDNA repeat on Chromosome R [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=D scenario_last_exon=D] Ca21chrR 1890785 1893173 + rdn18 1890785 1893173 1 1890785 1893173 1892098 1892301 RDN18 18S ribosomal RNA; component of the small (40S) ribosomal subunit; encoded in about 55 copies of the rDNA repeat on Chromosome R [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1893174 1893312 + its1 1893174 1893312 1 1893174 1893312 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1893313 1893469 + rdn58 1893313 1893469 1 1893313 1893469 RDN58 5.8S ribosomal RNA; component of the large (60S) ribosomal subunit; encoded in about 55 copies of the rDNA repeat on Chromosome R [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1893470 1893620 + its2 1893470 1893620 1 1893470 1893620 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1893621 1897042 + rdn25 1893621 1897042 1 1893621 1897042 1895078 1895263 RDN25 25S ribosomal RNA; component of the large (60S) ribosomal subunit; encoded in about 55 copies of the rDNA repeat on Chromosome R; in some strains the gene may contain the self-splicing group I intron (LSU) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1893804 1894073 - orf19.6834.10 1893804 1894073 1 1894073 1893804 1894073 1893804 TAR1 IPF27401.1 Ortholog of S. cerevisiae Tar1p, encoded within the 25S rRNA gene on the opposite strand; transcription is positively regulated by Tbf1p [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1898541 1898967 + orf19.7279.1 1898541 1898967 1 1898541 1898967 1898635 1898898 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1899204 1900496 - orf19.7279 1899204 1900496 1 1900496 1899204 1900436 1899537 IPF2865.1|Contig4-2992_0004|orf6.8360|CA5523|NIT2|CaO19.7279 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1900825 1901148 + orf19.7280 1900825 1901148 1 1900825 1901148 1900825 1901148 IPF27333.1|orf6.8361|CaO19.7280 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1902491 1904462 + orf19.7281 1902491 1904462 1 1902491 1904462 1902531 1904066 PDK2 IPF2861.1|Contig4-2992_0008|orf6.8362|CA5524|CaO19.7281|IPF2861 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to amphotericin B [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1904594 1906157 + orf19.7282 1904594 1906157 1 1904594 1906157 1904917 1906032 PEX13 IPF2859.1|Contig4-2992_0012|orf6.8363|CA5525|CaO19.7282 Protein required for peroxisomal protein import mediated by PTS1 and PTS2 targeting sequences; transcription is upregulated in an RHE model of oral candidiasis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1906456 1906824 - orf19.7283 1906456 1906824 1 1906824 1906456 1906824 1906456 IPF2858.1|Contig4-2992_0013|orf6.8364|CaO19.7283 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1907089 1908167 - orf19.7284 1907089 1908167 1 1908167 1907089 1907965 1907189 ASR2 IPF2857.1|IPF2857|Contig4-2992_0014|orf6.8365|CA5526|CaO19.7284 Gene regulated by cAMP and by osmotic stress; greater mRNA abundance observed in a cyr1 or ras1 homozygous null mutant than in wild type; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1908219 1909496 - orf19.7285 1908219 1909496 1 1909496 1908219 1909464 1908367 IPF2856.1|Contig4-2992_0015|orf6.8366|CA5527|PTI1|CaO19.7285|IPF2856 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1910013 1911455 - orf19.7286 1910013 1911455 1 1911455 1910013 1911418 1910216 RPN7 IPF2855.1|Contig4-2992_0017|Contig4-2992_0018|orf6.8367|orf6.8368|CA5528|orf19.7287|CaO19.7286 Predicted ORF in Assemblies 19, 20 and 21; regulated by Gcn2p and Gcn4p; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1911642 1913288 + orf19.7288 1911642 1913288 1 1911642 1913288 1911800 1913122 IPF2852.1|Contig4-2992_0020|orf6.8369|CA5529|CaO19.7288|ACD99|IPF2852 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1913144 1913890 - orf19.7290 1913144 1913890 1 1913890 1913144 1913738 1913235 IPF2850.1|Contig4-2992_0021|orf6.8371|CA5530|LSM1|CaO19.7290|SPB8 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1914338 1915408 + orf19.7291 1914338 1915408 1 1914338 1915408 1914361 1915368 IPF2848.1|Contig4-2774_0010|Contig4-2992_0023|orf6.8372|CA5531|GCD14|CaO19.7291 Protein not essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1915605 1917017 + orf19.7292 1915605 1917017 2 1915605|1915687 1915620|1917017 1915605 1916846 ARP2 IPF2847.1|Contig4-2774_0007|orf6.8373|CA5532|CaO19.7292 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to cytochalasin D; regulated by Gcn2p and Gcn4p [label_first_exon=CGD label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1916843 1919097 - orf19.7293 1916843 1919097 1 1919097 1916843 1918974 1916902 MPS1 IPF2846.1|Contig4-2774_0006|orf6.8374|CA5533|CaO19.7293|IPF2846 Predicted ORF in Assemblies 19, 20 and 21; essential for growth; periodic mRNA expression, peak at cell-cycle S/G2 phase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1919711 1919784 + tm(cau)4 1919711 1919784 1 1919711 1919784 tRNA-Met predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1919839 1921531 - orf19.7295 1919839 1921531 1 1921531 1919839 1921462 1919900 IPF2843.1|Contig4-2774_0003|Contig4-2774_0004|orf6.8376|CA5534|CaO19.7295|SCD5|IPF2843 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1921736 1923283 + ntar_1369 1921736 1923283 1 1921736 1923283 1922500 1922760 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1922010 1923401 - orf19.7296 1922010 1923401 1 1923401 1922010 1923260 1922208 IPF2839.1|Contig4-2774_0002|orf6.8377|CA5535|SLP99|CaO19.7296|IPF2839 Predicted ORF in Assemblies 19, 20 and 21; similar to stomatin mechanoreception protein; induced by Rgt1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1924764 1926134 - orf19.7297 1924764 1926134 1 1926134 1924764 1926092 1924941 IPF2837.2|Contig4-2774_0001|Contig4-2774_0012|orf6.8378|CA5536|CaO19.7297|IPF2837 Predicted ORF in Assemblies 19, 20 and 21; Hog1p-induced; Gcn4p-regulated; protein level decreased in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1924772 1924952 + ntar_1370 1924772 1924952 1 1924772 1924952 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1926311 1926589 + ntar_1371 1926311 1926589 1 1926311 1926589 1926311 1926505 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1926828 1930084 - orf19.7298 1926828 1930084 1 1930084 1926828 1929888 1926859 CHS2 IPF2836.1|Contig4-2472_0001|orf6.8379|CA5537|CaO19.7298 Chitin synthase; nonessential; required for wild-type chitin deposition in hyphae; transcription is regulated during dimorphic transition; Chs1p and Chs2p, but not Chs3p, are inhibited by the protoberberine HWY-289; fungal-specific [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1930891 1932768 + orf19.7300 1930891 1932768 1 1930891 1932768 1931876 1932700 IPF2830.1|Contig4-2472_0004|orf6.8381|CA5538|CaO19.7300|IPF2830 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1931048 1931347 - orf19.7299.1 1931048 1931347 1 1931347 1931048 1931347 1931048 IPF27337.1 [NOT TRANSCRIBED?] ORF Predicted by Annotation Working Group [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1933074 1934844 - orf19.7301 1933074 1934844 1 1934844 1933074 1934844 1933084 IPF2829.1|Contig4-2245_0002|Contig4-2245_0004|orf6.1910|orf6.8382|orf6.8383|CA5539|CA5540|orf19.7302|Cirt1b.3f Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chrR 1935993 1936730 + orf19.7303 1935993 1936730 1 1935993 1936730 1935993 1936730 IPF2827.2|Contig4-2245_0006|orf6.8384|CA5541|CaO19.7303|IPF2827 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1936298 1938588 - orf19.7304 1936298 1938588 1 1938588 1936298 1938292 1936814 IPF19812.1|Contig4-2245_0009|orf6.8385|CA5542|IPF19812|CaO19.7304 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1938585 1938906 + ntar_1372 1938585 1938906 1 1938585 1938906 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1938912 1939369 + ntar_1373 1938912 1939369 1 1938912 1939369 1938912 1939115 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1940341 1941980 - orf19.7305 1940341 1941980 1 1941980 1940341 1941773 1940490 IPF5988.1|Contig4-2983_0002|orf6.8386|CA5543|CaO19.7305|IPF5988 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1942136 1943477 - orf19.7306 1942136 1943477 1 1943477 1942136 1943395 1942346 IPF5987|Contig4-2983_0004|YPR127W|IPF5987.1|orf6.8387|CA5544|YPR127|CaO19.7306 Protein of aldo-keto reductase family; increased transcription associated with MDR1 overexpression, benomyl or long-term fluconazole treatment; overexpression does not affect drug or oxidative stress sensitivity [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1943923 1944963 - orf19.7307 1943923 1944963 1 1944963 1943923 1944876 1944019 orf6.8388|IPF5986.1|Contig4-2983_0005|CA5545|CaO19.7307|IPF5986 Putative oxidoreductase; similar to S. cerevisiae Yml125p; possible Kex2p substrate [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1945159 1947061 - orf19.7308 1945159 1947061 2 1947061|1946763 1946978|1945159 1947002 1945442 TUB1 IPF5983.1|Contig4-2983_0007|orf6.8389|CA5546|TUB1.3 Alpha-tubulin; gene has intron; complements cold-sensitivity of S. cerevisiae tub1 mutant; C. albicans has single alpha-tubulin gene, whereas S. cerevisiae has two (TUB1, TUB3); farnesol-upregulated in biofilm [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1947557 1948780 + ntar_1374 1947557 1948780 1 1947557 1948780 1948083 1948394 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1947606 1950048 - orf19.7310 1947606 1950048 1 1950048 1947606 1950017 1947651 orf6.8391|IPF5981|IPF5981.1|Contig4-2983_0010|CA5547|CaO19.7310 Protein similar to S. cerevisiae Gin3p; transcription is upregulated in response to treatment with ciclopirox olamine; positively regulated by Sfu1p; Hog1p, fluconazole-downregulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chrR 1950486 1951440 + orf19.7311 1950486 1951440 1 1950486 1951440 1950737 1951321 IPF5978.1|Contig4-2983_0015|orf6.8392|CA5548|CaO19.7311|IPF5978 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1951383 1952933 - orf19.7312 1951383 1952933 1 1952933 1951383 1952785 1951430 ERG13 IPF5977.1|Contig4-2983_0016|orf6.8393|CA5549|CaO19.7312 Protein similar to S. cerevisiae Erg13p, which is involved in ergosterol biosynthesis; transposon mutation affects filamentous growth; amphotericin B, caspofungin repressed; detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1953990 1955613 - orf19.7313 1953990 1955613 1 1955613 1953990 1955514 1954069 SSU1 IPF5976.1|Contig4-2983_0020|orf6.8394|CA5550|SSU11|CaO19.7313 Protein similar to S. cerevisiae Ssu1p sulfite transport protein; transposon mutation affects filamentous growth; regulated by Gcn2p and Gcn4p; induced by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1957397 1958844 + orf19.7314 1957397 1958844 1 1957397 1958844 1957893 1958690 CDG1 IPF5972.1|Contig4-2983_0023|orf6.8395|CA5551|CaO19.7314|IPF5972 Protein described as similar to cysteine dioxygenases; expression is regulated upon white-opaque switching [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1958725 1959725 - orf19.7316 1958725 1959725 1 1959725 1958725 1959725 1958820 IPF5971.1|Contig4-2983_0024|Contig4-2983_0025|orf6.8397|CA5552|CaO19.7316|IPF5971 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); induced by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1959961 1961511 - orf19.7317 1959961 1961511 1 1961511 1959961 1961409 1959961 UGA33|IPF5969.2|Contig4-2511_0002|Contig4-2983_0026|orf6.8398|orf6.8399|CA5553|CA5554|orf19.7318|IPF1960.3f Predicted zinc-finger protein of unknown function; has similarity to S. cerevisiae Uga3p, which is a transcription factor involved in the regulation of gamma-aminobutyrate metabolism genes [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1961677 1963419 + orf19.7319 1961677 1963419 1 1961677 1963419 1961827 1963332 SUC1 IPF1962.1|Contig4-2511_0004|orf6.8400|CA5555|CaO19.7319 Putative transcriptional regulator with N-terminal zinc finger; regulates alpha-glucosidase in C. albicans and S. cerevisiae; in S. cerevisiae, complements suc2 mutant sucrose utilization defect and mal13 mutant maltase defect [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1963423 1964703 - orf19.7320 1963423 1964703 1 1964703 1963423 1964703 1963423 LIP7 IPF1964.2|Contig4-2511_0006|orf6.8401|CA5556|CaO19.7320 Probable lipase, part of a gene family whose members are differentially expressed during infection; lacks a signal sequence for secretion, unlike other family members; may have a role in nutrition or in creating an acidic microenvironment [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1964867 1967027 - orf19.7321 1964867 1967027 1 1967027 1964867 1966892 1965072 IPF1968.2|Contig4-2511_0007|Contig4-2511_0008|orf6.8402|CA5557|CaO19.7321|IPF1968 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1967072 1967264 + ntar_1375 1967072 1967264 1 1967072 1967264 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1967229 1967895 - orf19.7322 1967229 1967895 1 1967895 1967229 1967721 1967278 IPF1969.1|Contig4-2511_0010|orf6.8403|CA5558|CaO19.7322|IPF1969 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1968757 1970388 - orf19.7323 1968757 1970388 1 1970388 1968757 1970339 1968870 CBP1 CBP|IPF1971.2|orf6.8404|CA5559|CaO19.7323 Corticosteroid binding protein; transcription induced at late log-phase or upon adherence to polystyrene; not induced by corticosterone; contains a possible NAD/FAD binding region; regulated by Nrg1p, Tup1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1969457 1969690 + ntar_1376 1969457 1969690 1 1969457 1969690 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 1972013 1973532 + orf19.7324 1972013 1973532 1 1972013 1973532 1972365 1973384 THI13 IPF1974.1|Contig4-3033_0005|orf6.8405|CA5560|CaO19.7324 Protein not essential for viability; similar to S. cerevisiae Thi13p, which is involved in synthesis of the thiamine precursor hydroxymethylpyrimidine; induced by nitric oxide in yhb1 mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1973418 1974512 - orf19.7325 1973418 1974512 1 1974512 1973418 1974446 1973541 IPF1975.1|Contig4-3033_0006|orf6.8406|CA5561|CaO19.7325|SCO1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1974858 1976692 + orf19.7326 1974858 1976692 1 1974858 1976692 1974889 1976628 IPF1977.2|Contig4-3033_0007|Contig4-3033_0008|orf6.8407|CA5562|IPF1977|CaO19.7326 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1976577 1977510 - orf19.7327 1976577 1977510 1 1977510 1976577 1977431 1976856 PHO88 IPF1978.1|Contig4-3033_0009|orf6.8408|CA5563|CaO19.7327 Putative role in phosphate transport; biofilm-regulated expression; amphotericin B repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1977725 1980688 - orf19.7328 1977725 1980688 1 1980688 1977725 1980530 1977825 orf6.8409|IPF1980.1|Contig4-3033_0011|CA5564|CaO19.7328|CAP100|IPF1980 Gene transcription regulated by Mig1p and Tup1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1981017 1981856 + orf19.7329 1981017 1981856 1 1981017 1981856 1981163 1981666 IPF1981.1|Contig4-3033_0014|orf6.8410|CA5565|CaO19.7329|QRI8 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1982172 1982885 - orf19.7330 1982172 1982885 1 1982885 1982172 1982885 1982172 IPF1983.1|Contig4-3033_0015|orf6.8411|CA5566|CaO19.7330|PET18 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1983245 1984851 + orf19.7331 1983245 1984851 1 1983245 1984851 1983245 1984831 FCY24 IPF1985.2|Contig4-3033_0016|Contig4-3033_0017|orf6.8412|CA5567|CaO19.7331|TPN12 Putative transporter; more similar to S. cerevisiae Tpn1p, which is a vitamin B6 transporter, than to purine-cytosine permeases; transcription is regulated by Nrg1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chrR 1985113 1988863 + orf19.7332 1985113 1988863 1 1985113 1988863 1985195 1988782 ELF1 IPF1989.1|Contig4-3033_0019|orf6.8413|CA5568|CaO19.7332 Protein required for wild-type morphology, growth; Walker A and B (ATP/GTP binding) motifs, ABC transporter consensus; expressed in hyphal, pseudohyphal, and yeast form, upregulated in biofilm; S. pombe homolog is ABC ATPase of mRNA export [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 1989080 1990435 + orf19.7335 1989080 1990435 2 1989080|1989352 1989204|1990435 1989161 1990063 PRE8 IPF1990.1|Contig4-3033_0021|orf6.8416|CA5569|CaO19.7335 Protein described as alpha-2_sc subunit of proteasome; macrophage-induced protein; regulated by Gcn2p and Gcn4p; transcription is positively regulated by Tbf1p; protein detected by mass spec in stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 1990499 1992313 - orf19.7336 1990499 1992313 1 1992313 1990499 1992313 1990499 IPF1992.1|Contig4-3033_0023|Contig4-3033_0024|orf6.8417|CA5570|CaO19.7336|IPF1992 Predicted membrane transporter, member of the drug:proton antiporter (14 spanner) (DHA2) family, major facilitator superfamily (MFS) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 1999195 1999926 + ntar_1377 1999195 1999926 1 1999195 1999926 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2000142 2002702 + orf19.7337 2000142 2002702 1 2000142 2002702 2000400 2002514 IPF2001.1|Contig4-1848_0005|Contig4-2924_0003|Contig4-2924_0004|orf6.8418|CA5571|CaO19.7337|IPF2001 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2002929 2003301 + ntar_1378 2002929 2003301 1 2002929 2003301 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2002983 2005913 - orf19.7339 2002983 2005913 2 2005913|2005498 2005655|2002983 2005913 2002983 BGL22 IPF2004.1|Contig4-2924_0005|orf6.8420|CA5572|orf19.7339.1|CaO19.7339|BGL99|CA5573|IPF2005|IPF2005.1 [NOT TRANSCRIBED?] Putative glucanase; induced during cell wall regeneration [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 2003435 2005900 + ntar_1379 2003435 2005900 1 2003435 2005900 2004301 2004459 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2006118 2006764 - orf19.7340 2006118 2006764 1 2006764 2006118 2006764 2006432 IPF27331.1|orf6.8421|CaO19.7340 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chrR 2006819 2008093 - orf19.7341 2006819 2008093 2 2008093|2007872 2007940|2006819 2007958 2006911 IPF2007.1|Contig4-2924_0009|orf6.8422|CA5574|CaO19.7341|IPF2007 Predicted ORF in Assemblies 19, 20 and 21; ketoconazole-repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2009048 2009119 - td(guc)7 2009048 2009119 1 2009119 2009048 tRNA-Asp predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 2009624 2010407 - ntar_1380 2009624 2010407 1 2010407 2009624 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2009702 2010377 + ntar_1381 2009702 2010377 1 2009702 2010377 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2012114 2012744 - ntar_1382 2012114 2012744 1 2012744 2012114 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2015188 2015873 - orf19.7341.1 2015188 2015873 1 2015873 2015188 2015578 2015285 ORF added to Assembly 21 based on comparative genome analysis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2017305 2021560 + orf19.7342 2017305 2021560 1 2017305 2021560 2017305 2021417 AXL1 IPF19813.1|Contig4-2379_0005|orf6.8423|CA5575|CaO19.7342|IPF19813 Protein of unknown function, induced by alpha factor; transcription is upregulated in an RHE model of oral candidiasis and in clinical isolates from HIV+ patients with oral candidiasis [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chrR 2018557 2018745 - ntar_1383 2018557 2018745 1 2018745 2018557 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2018894 2019088 - ntar_1384 2018894 2019088 1 2019088 2018894 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2021680 2023508 + orf19.7343 2021680 2023508 1 2021680 2023508 2021942 2023318 IPF12538.2|Contig4-2379_0002|orf6.8424|CA5576|CaO19.7343|PRP4 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2023595 2026470 + orf19.7344 2023595 2026470 1 2023595 2026470 2023763 2026270 IPF12537.1|Contig4-2379_0001|orf6.8425|CA5577|CaO19.7344|HDA3|IPF12537 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2026337 2027740 - orf19.7345 2026337 2027740 1 2027740 2026337 2027614 2026610 IPF12536.3|Contig4-2379_0006|orf6.8426|CA5578|CaO19.7345|IPF12536|IPF12536.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2027893 2028845 - orf19.6612 2027893 2028845 1 2028845 2027893 2028770 2027970 IPF7932.1|orf6.6224|CA3850|CaO19.6612|IPF7932 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2029011 2031996 - orf19.6610 2029011 2031996 1 2031996 2029011 2031915 2029141 IPF7938.2|Contig4-2319_0001|Contig4-2790_0015|Contig4-2790_0016|orf6.6222|CA3849|STU2|CaO19.6610|IPF7938 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2032354 2034768 - orf19.6608 2032354 2034768 1 2034768 2032354 2034660 2032492 IPF7940|IPF7940.1|Contig4-2790_0012|orf6.6220|CA3848|CaO19.6608 Predicted ORF in Assemblies 19, 20 and 21; downregulation correlates with clinical development of fluconazole resistance [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chrR 2035026 2035284 - ntar_1385 2035026 2035284 1 2035284 2035026 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2035469 2036503 - orf19.6607 2035469 2036503 1 2036503 2035469 2036446 2035832 IPF7942.1|Contig4-2790_0009|orf6.6219|CA3847|CaO19.6607|IPF7942 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2037344 2038879 - orf19.6606 2037344 2038879 1 2038879 2037344 2038879 2037515 IPF7943.2|Contig4-2790_0007|orf6.6218|CA3846|CaO19.6606|IPF7943 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chrR 2038878 2040253 + orf19.6605 2038878 2040253 1 2038878 2040253 2039230 2040093 IPF7944.2|Contig4-2790_0006|orf6.6217|CA3845|CaO19.6605|IPF7944 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2039939 2041561 - orf19.6604 2039939 2041561 2 2041561|2041304 2041421|2039939 2041301 2040213 IPF7945.2|Contig4-2790_0004|orf6.6216|CA3844|CaO19.6604|IPF7945 Predicted ORF in Assemblies 19, 20 and 21; greater mRNA abundance observed in a cyr1 homozygous null mutant than in wild type [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2041638 2042392 + ntar_1386 2041638 2042392 1 2041638 2042392 2042003 2042155 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2042071 2042417 - ntar_1387 2042071 2042417 1 2042417 2042071 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2042681 2043770 + orf19.6602 2042681 2043770 1 2042681 2043770 2042808 2043677 IPF7947.1|Contig4-2790_0002|orf6.6214|CA3843|CaO19.6602|FMP53|IPF7947 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2043388 2044431 - orf19.6601.1 2043388 2044431 1 2044431 2043388 2044321 2043818 YKE2 IPF7948.2|Contig4-2790_0001|CA3842|YKE2.3f|YKE2.3 Possible cytoskeletal modulator; transcription induced upon yeast-to-hyphal switch; regulated by Nrg1p, Tup1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2044560 2044840 + ntar_1388 2044560 2044840 1 2044560 2044840 2044560 2044733 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2044859 2046402 - orf19.6601 2044859 2046402 1 2046402 2044859 2046291 2045083 IPF16640.2|orf6.6213|CA3841|CaO19.6601|IPF16640 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2047194 2048601 - orf19.6600 2047194 2048601 1 2048601 2047194 2048280 2047690 IPF12745.1|Contig4-2356_0001|orf6.6212|CA3840|CaO19.6600|IPF12745 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2049231 2049324 + tn(guu)4 2049231 2049324 2 2049231|2049289 2049268|2049324 tRNA-Asn predicted by tRNAscan-SE [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 2049404 2050025 - orf19.6599.1 2049404 2050025 1 2050025 2049404 2049950 2049756 IPF12744.2|Contig4-2356_0004|CA3839|IPF12744 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2050228 2052678 + orf19.6598 2050228 2052678 1 2050228 2052678 2050368 2052509 WAL1 IPF12743.2|Contig4-2356_0006|orf6.6210|CA3838|CaO19.6598|LAS17 Protein required for hyphal growth and for wild-type cell morphology, polarized budding, endocytosis, vacuole morphology; similar to Wiskott-Aldrich syndrome protein; localizes to cortical actin patches and hyphal tips [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2053040 2054593 + orf19.6597 2053040 2054593 1 2053040 2054593 2053092 2054267 IPF12741.2|orf6.6209|CA3837|CaO19.6597|IPF12741 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2054016 2055331 - orf19.6596 2054016 2055331 1 2055331 2054016 2055203 2054292 IPF8179.2|Contig4-2811_0030|orf6.6208|CA3836|CaO19.6596|IPF8179 Protein of unknown function; possibly transcriptionally regulated by Tac1p; transcriptionally activated by Mnl1p under weak acid stress; protein detected by mass spec in exponential and stationary phase cultures [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2055766 2056044 + ntar_1389 2055766 2056044 1 2055766 2056044 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2055871 2057241 - orf19.6595 2055871 2057241 1 2057241 2055871 2057241 2055871 RTA4 IPF8181.1|Contig4-2811_0027|orf6.6207|YOR049C|CA3835|CaO19.6595|RSB12 Predicted ORF in Assemblies 19, 20 and 21; similar to S. cerevisiae Yor049cp, which is involved in fatty acid transport; transposon mutation affects filamentous growth; alkaline downregulated; caspofungin induced [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 2059145 2061382 - orf19.6594 2059145 2061382 1 2061382 2059145 2061195 2059297 PLB3 IPF8186.1|Contig4-2811_0019|orf6.6206|PLB4|CA3834|CaO19.6594 GPI-anchored cell surface phospholipase B; similar to S. cerevisiae Plb3p; fungal-specific (no human or murine homolog); transcription is positively regulated by Tbf1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2061248 2061494 + ntar_1390 2061248 2061494 1 2061248 2061494 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2062819 2063291 + ntar_1391 2062819 2063291 1 2062819 2063291 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2063769 2065697 + orf19.6592 2063769 2065697 1 2063769 2065697 2063769 2065538 IPF8192.1|Contig4-2811_0010|orf6.6204|CA3833|CaO19.6592|IPF8192 Predicted membrane transporter, member of the aromatic acid:proton symporter (AAHS) family, major facilitator superfamily (MFS) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chrR 2063988 2064672 - ntar_1392 2063988 2064672 1 2064672 2063988 2064282 2064127 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2065723 2066288 - ntar_1393 2065723 2066288 1 2066288 2065723 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2066373 2067817 + orf19.6591 2066373 2067817 1 2066373 2067817 2066600 2067778 IPF8193.1|Contig4-2811_0003|orf6.6203|CA3832|PCD1|CaO19.6591|IPF8193 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2067909 2068679 + orf19.6590 2067909 2068679 1 2067909 2068679 2068017 2068583 IPF8194.1|Contig4-2811_0001|orf6.6202|CA3831|CaO19.6590|VMA22 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2068592 2069997 - orf19.6589 2068592 2069997 1 2069997 2068592 2069970 2068624 IPF8195.2|Contig4-2811_0031|orf6.6201|CA3830|SSF1|CaO19.6589|SSF1.3eoc|IPF8195.1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2070097 2071868 + orf19.7546 2070097 2071868 1 2070097 2071868 2070097 2071701 IPF17103.3|Contig4-1679_0002|orf6.8894|CA5957|CaO19.7546|RRP3|RRP3.3eoc|IPF17103.2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chrR 2071714 2073144 - orf19.7547 2071714 2073144 1 2073144 2071714 2072857 2071769 IPF17102.2|Contig4-1679_0001|orf6.8895|CA5958|PIB1|CaO19.7547 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2073408 2074555 + orf19.7548 2073408 2074555 1 2073408 2074555 2073450 2073986 IPF12936.2|orf6.8896|CA5959|SRB7|CaO19.7548 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2073902 2076290 - orf19.7549 2073902 2076290 1 2076290 2073902 2076212 2074035 PMT5 IPF12934.1|Contig4-2433_0005|orf6.8897|CA5960|CaO19.7549 Protein mannosyltransferase with an unknown role, expressed at extremely low levels; not required for wild-type hyphal growth, drug resistance, or virulence in mouse systemic infection; one of five PMT family members [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2076354 2077331 + ntar_1394.1 2076354 2077331 1 2076354 2077331 2076752 2076913 MANUAL ANNOTATION (edit of ntar_1394); ntar_1176-like Ca21chrR 2077350 2078101 + ntar_1394.2 2077350 2078101 1 2077350 2078101 2077565 2077753 MANUAL ANNOTATION (edit of ntar_1394); ntar_1176-like Ca21chrR 2078021 2080150 - orf19.7550 2078021 2080150 1 2080150 2078021 2080150 2078114 IFA14 IPF12930.2|Contig4-2433_0007|orf6.8898|CA5961|CaO19.7550 Predicted ORF in Assemblies 19, 20 and 21; Plc1p-regulated; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chrR 2081802 2081975 + ntar_1394.5 2081802 2081975 1 2081802 2081975 2081802 2081975 MANUAL ANNOTATION; ntar_1176-like Ca21chrR 2082458 2082861 + ntar_1395 2082458 2082861 1 2082458 2082861 2082566 2082748 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2083441 2083962 + ntar_1396 2083441 2083962 1 2083441 2083962 2083527 2083706 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2084245 2084608 + ntar_1396.5 2084245 2084608 1 2084245 2084608 2084351 2084530 MANUAL ANNOTATION; ntar_1176-like Ca21chrR 2085050 2085521 + ntar_1397.1 2085050 2085521 1 2085050 2085521 2085113 2085289 MANUAL ANNOTATION (edit of ntar_1397); ntar_1176-like Ca21chrR 2085819 2086396 + ntar_1398 2085819 2086396 1 2085819 2086396 2085948 2086151 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2086821 2087232 + ntar_1399 2086821 2087232 1 2086821 2087232 2086944 2087123 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2087639 2087911 + ntar_1400 2087639 2087911 1 2087639 2087911 2087671 2087850 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2088379 2088752 + ntar_1400.50 2088379 2088752 1 2088379 2088752 2088437 2088619 MANUAL ANNOTATION; ntar_1176-like Ca21chrR 2089214 2089470 + ntar_1400.51 2089214 2089470 1 2089214 2089470 2089234 2089419 MANUAL ANNOTATION; ntar_1176-like Ca21chrR 2089782 2089961 + ntar_1400.52 2089782 2089961 1 2089782 2089961 2089782 2089961 MANUAL ANNOTATION; ntar_1176-like Ca21chrR 2090707 2092636 + orf19.7551 2090707 2092636 1 2090707 2092636 2090795 2092468 ALO1 IPF967.1|Contig4-3105_0006|Contig4-3105_0007|orf6.8899|CA5962|CaO19.7551 D-Arabinono-1,4-lactone oxidase, involved in biosynthesis of dehydro-D-arabinono-1,4-lactone, which has a protective role against oxidative damage; required for full virulence in a mouse model of systemic infection [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2092514 2095423 - orf19.7552 2092514 2095423 1 2095423 2092514 2095287 2092669 IPF966.1|Contig4-3105_0009|orf6.8900|CA5963|CaO19.7552|IPF966 Predicted ORF in Assemblies 19, 20 and 21; downregulated during core stress response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2095846 2096774 + orf19.7553 2095846 2096774 1 2095846 2096774 2095906 2096619 IPF963.1|Contig4-3105_0010|orf6.8901|CA5964|CaO19.7553|IPF963 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2096717 2097154 - orf19.7555 2096717 2097154 1 2097154 2096717 2097154 2096717 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 2096985 2098897 + orf19.7554 2096985 2098897 1 2096985 2098897 2097128 2098810 orf6.8902|IPF961.1|Contig4-3105_0012|CA5965|CaO19.7554|IPF961 Putative transporter; slightly similar to the Sit1p siderophore transporter; induced by nitric oxide in yhb1 mutant [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2098802 2099745 - orf19.7556 2098802 2099745 1 2099745 2098802 2099576 2098932 IPF959.1|Contig4-3105_0014|orf6.8904|CA5966|CaO19.7556|IPF959 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2099832 2103427 + orf19.7558 2099832 2103427 1 2099832 2103427 2100853 2103315 YTA6 IPF955.1|Contig4-3105_0017|orf6.8906|CA5967|CaO19.7558|SAP100|IPF955 Protein similar to S. cerevisiae Yta6p ATPase; transposon mutation affects filamentous growth; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2100350 2100712 - orf19.7557 2100350 2100712 1 2100712 2100350 2100712 2100350 FGR46 IPF27261.1|Contig4-3105_0015|orf6.8905|CaO19.7557 Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 2106168 2108878 + orf19.7561 2106168 2108878 1 2106168 2108878 2106215 2108878 DEF1 IPF946.1|EDT1|Contig4-2780_0003|Contig4-3105_0026|Contig4-3105_0028|orf6.8909|CA5968|EED1|CaO19.7561|IPF946 Protein required for filamentous growth and for escape from epithelial cells and dissemination in an RHE model; transcription induced in oral candidiasis clinical isolates; induced by fluconazole, high cell density; hyphally regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=H scenario_last_exon=H] Ca21chrR 2112794 2114139 - orf19.7563 2112794 2114139 1 2114139 2112794 2114062 2113037 BET2 IPF941.1|Contig4-3105_0030|orf6.8911|CA5969|CaO19.7563 Transcription is regulated by Mig1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2114321 2116580 - orf19.7564 2114321 2116580 1 2116580 2114321 2116462 2114336 DPB2 IPF940.1|Contig4-3105_0032|orf6.8912|CA5970|CaO19.7564 Probable subunit of DNA polymerase II (DNA polymerase epsilon), similar to S. cerevisiae Dpb2p; essential for viability [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2118518 2120543 + orf19.7565 2118518 2120543 1 2118518 2120543 2118782 2120479 GNP3 IPF937.1|Contig4-3105_0039|orf6.8913|GNP2|CA5971|CaO19.7565 Putative high-affinity glutamine permease; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2122690 2124742 + orf19.7566 2122690 2124742 1 2122690 2124742 2122928 2124643 GNP1|IPF934.1|Contig4-3105_0041|orf6.8914|GNP2|CA5972|CaO19.7566 Putative protein of unknown function, transcription is upregulated in clinical isolates from HIV+ patients with oral candidiasis; alkaline upregulated by Rim101p; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2125399 2126766 + orf19.7567 2125399 2126766 1 2125399 2126766 2125477 2126766 IPF931.1|Contig4-3105_0044|orf6.8915|CA5973|CaO19.7567|IPF931 Predicted ORF in Assemblies 19, 20 and 21; transcription is induced in response to alpha pheromone in SpiderM medium [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chrR 2127071 2127916 + orf19.7568 2127071 2127916 1 2127071 2127916 2127071 2127916 IPF930.2|Contig4-3105_0046|orf6.8916|CA5974|CaO19.7568|IPF930 [NOT TRANSCRIBED?] Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 2127958 2129763 - orf19.7569 2127958 2129763 1 2129763 2127958 2129688 2128138 SIK1 IPF929.2|Contig4-3105_0047|orf6.8917|CA5975|CaO19.7569 Predicted ORF in Assemblies 19, 20 and 21; physically interacts with TAP-tagged Nop1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2129917 2132559 - orf19.7570 2129917 2132559 1 2132559 2129917 2132371 2129960 UGA3|IPF928.1|Contig4-3105_0048|orf6.8918|CA5976|CaO19.7570|IPF928 Putative transcription factor with zinc cluster DNA-binding motif; has similarity to S. cerevisiae Uga3p, which is a transcription factor involved in the regulation of gamma-aminobutyrate metabolism genes [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2133606 2134873 + orf19.7571 2133606 2134873 2 2133606|2134186 2133741|2134873 2133698 2134585 UBC4 IPF926.1|Contig4-3105_0053|orf6.8919|CA5977|UBC4.3 Protein similar to S. cerevisiae ubiquitin conjugating enzyme Ubc4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2135031 2139423 + orf19.7572 2135031 2139423 1 2135031 2139423 2135360 2139283 SPT7 IPF925.1|Contig4-3105_0056|Contig4-3105_0057|orf6.8920|CA5978|CaO19.7572 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to toxic ergosterol analog, and to amphotericin B [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2139766 2144310 + orf19.7574 2139766 2144310 1 2139766 2144310 2139917 2144236 IPF921.1|Contig4-3105_0059|Contig4-3105_0061|orf6.8922|CA5979|CaO19.7574|IPF921 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2144202 2144797 - orf19.7576 2144202 2144797 2 2144797|2144643 2144710|2144202 2144797 2144339 IPF918|IPF918.1|Contig4-3105_0062|orf6.8924|CA5980|CaO19.7576 Protein not essential for viability [label_first_exon=CGD label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2144900 2146525 - orf19.7577 2144900 2146525 1 2146525 2144900 2146359 2145052 MSS51 IPF917.1|Contig4-3105_0063|orf6.8925|CA5981|CaO19.7577 Putative mRNA maturation factor; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2146597 2147627 - orf19.7578 2146597 2147627 1 2147627 2146597 2147575 2146799 IPF915.1|Contig4-3105_0066|orf6.8926|CA5982|CaO19.7578|YOS9|IPF915 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2147997 2149718 + orf19.7579 2147997 2149718 1 2147997 2149718 2148076 2149641 FGR34 IPF913.1|Contig4-3105_0067|orf6.8927|CA5983|CaO19.7579|IPF913 Protein lacking an ortholog in S. cerevisiae; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2148388 2148572 - ntar_1401 2148388 2148572 1 2148572 2148388 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2149352 2149492 - ntar_1402 2149352 2149492 1 2149492 2149352 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2149878 2150324 + orf19.7580 2149878 2150324 1 2149878 2150324 2149931 2150245 IPF912.1|Contig4-3105_0068|orf6.8928|CaO19.7580 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2150620 2152265 + orf19.7581 2150620 2152265 1 2150620 2152265 2150750 2152165 IPF911.1|Contig4-3105_0069|orf6.8929|CA5984|CUS1|CaO19.7581 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2152087 2154278 - orf19.7583 2152087 2154278 1 2154278 2152087 2154225 2152180 ZCF39|OAF1|IPF907.2|Contig4-3105_0071|Contig4-3105_0072|orf6.8931|CA5985|CaO19.7583|IPF907 Putative transcription factor with zinc cluster DNA-binding motif; not essential for viability; filament induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2154879 2155681 + ntar_1403 2154879 2155681 1 2154879 2155681 2155283 2155519 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2155570 2157254 - orf19.7585 2155570 2157254 1 2157254 2155570 2157196 2155634 INO1 IPF904.1|Contig4-3105_0074|orf6.8933|CA5986|CaO19.7585 Inositol-1-phosphate synthase; enzyme of inositol biosynthesis; antigenic in human; repressed by farnesol (in biofilm) or caspofungin; regulated during planktonic growth; upstream inositol/choline regulatory element; glycosylation predicted [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2161511 2163790 + orf19.7586 2161511 2163790 1 2161511 2163790 2161835 2163538 CHT3 IPF696.1|Contig4-3108_0002|orf6.8934|CA5987|CaO19.7586 Chitinase, major; functional homolog of S. cerevisiae Cts1p; 4 N-glycosylation motifs; possible O-mannosylated region; putative signal peptide; hyphal-repressed; farnesol upregulated in biofilm; regulated by Efg1p, Cyr1p, Ras1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2163652 2164687 - orf19.7588 2163652 2164687 1 2164687 2163652 2164594 2163773 IPF693.1|Contig4-3108_0004|orf6.8936|CA5988|CaO19.7588|IPF693 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2164701 2165498 + orf19.7589 2164701 2165498 1 2164701 2165498 2164701 2165435 IPF692.1|Contig4-3108_0007|orf6.8937|CA5989|CaO19.7589|IPF692 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction); transcription is activated in the presence of elevated CO2 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chrR 2165254 2165459 - ntar_1404 2165254 2165459 1 2165459 2165254 2165448 2165254 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2165820 2168449 + orf19.7590 2165820 2168449 1 2165820 2168449 2165996 2168158 IPF690.2|Contig4-3108_0008|Contig4-3108_0010|Contig4-3108_0011|CA5990|CA5991|IPF690.3f|orf19.7591|IPF690.5f|orf6.8938 Protein described as NADH-ubiquinone oxidoreductase; identified in detergent-resistant membrane fraction (possible lipid raft component); predicted N-terminal acetylation; repressed by nitric oxide [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2169784 2170604 + ntar_1405 2169784 2170604 1 2169784 2170604 2170226 2170387 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2172065 2172333 - ntar_1406 2172065 2172333 1 2172333 2172065 2172333 2172148 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2172092 2174894 + orf19.7592 2172092 2174894 1 2172092 2174894 2172618 2174708 FAA4 IPF20033.1|Contig4-3108_0019|Contig4-3108_0020|orf6.8940|CA5992|CaO19.7592 Predicted acyl CoA synthase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2174732 2176501 - orf19.7593 2174732 2176501 1 2176501 2174732 2176379 2174925 IPF679.1|Contig4-3108_0024|orf6.8941|CA5993|CaO19.7593|ASP1 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2176756 2178309 + orf19.7594 2176756 2178309 1 2176756 2178309 2176858 2177499 IPF677.1|Contig4-3108_0026|orf6.8942|CA5994|CaO19.7594|IPF677 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2177522 2178950 - orf19.7595 2177522 2178950 1 2178950 2177522 2178885 2177557 IPF676.1|Contig4-3108_0027|orf6.8943|CA5995|CaO19.7595|IPF676 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2179491 2180523 + orf19.7596 2179491 2180523 1 2179491 2180523 2179540 2180523 IPF673.1|Contig4-3108_0030|orf6.8944|CA5996|CaO19.7596|PMU2|IPF673 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=C scenario_last_exon=C] Ca21chrR 2181057 2182004 + orf19.7597 2181057 2182004 1 2181057 2182004 2181057 2182004 PGA12 IPF672.1|Contig4-3108_0031|orf6.8945|CA5997|PMU3|CaO19.7597 Putative GPI-anchored protein of unknown function [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 2182874 2184313 + orf19.7598 2182874 2184313 1 2182874 2184313 2182918 2184237 IPF670.2|Contig4-3108_0032|orf6.8946|CA5998|AHC1|CaO19.7598|IPF670 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2184429 2186452 + orf19.7599 2184429 2186452 1 2184429 2186452 2184474 2186384 UTP5 IPF668.2|Contig4-3108_0035|orf6.8947|CA5999|CaO19.7599|IPF668 Predicted ORF in Assemblies 19, 20 and 21; mutation confers resistance to 5-fluorocytosine (5-FC), 5-fluorouracil (5-FU), and tubercidin (7-deazaadenosine); physically interacts with TAP-tagged Nop1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2186408 2187901 - orf19.7600 2186408 2187901 2 2187901|2187622 2187827|2186408 2187850 2186501 FDH3 IPF666.1|Contig4-3108_0036|orf6.8948|CA6000|FDH11|FDH11.3 Putative protein of glycine catabolism; downregulated by Efg1p under yeast-form but not hyphal growth conditions; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2188349 2189545 + orf19.7601 2188349 2189545 1 2188349 2189545 2188567 2189382 IPF662.1|Contig4-3108_0038|orf6.8949|CA6001|MRM2|CaO19.7601|IPF662 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2189392 2190542 - orf19.7602 2189392 2190542 1 2190542 2189392 2190483 2189443 IPF661.1|Contig4-3108_0039|orf6.8950|CA6002|CaO19.7602|AHA1|IPF661 Predicted ORF in Assemblies 19, 20 and 21; heavy metal (cadmium) stress-induced; oxidative stress-induced via Cap1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2190682 2191627 + orf19.7603 2190682 2191627 1 2190682 2191627 2191147 2191473 IPF660.1|Contig4-3108_0041|orf6.8951|CA6003|CaO19.7603|IPF660 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2191397 2195474 - orf19.7604 2191397 2195474 1 2195474 2191397 2195374 2191550 IPF659.1|Contig4-3108_0044|orf6.8952|CA6004|CaO19.7604|TRS120 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2195719 2196702 + orf19.7605 2195719 2196702 1 2195719 2196702 2195778 2196596 PUP1 IPF654.1|Contig4-3108_0046|orf6.8953|CA6005|CaO19.7605 Predicted ORF in Assemblies 19, 20 and 21; macrophage/pseudohyphal-repressed [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2197326 2198257 + orf19.7606 2197326 2198257 1 2197326 2198257 2197624 2198115 IPF652.1|Contig4-3108_0049|orf6.8954|CA6006|CaO19.7606|IPF652 Predicted ORF in Assemblies 19, 20 and 21; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=G scenario_last_exon=G] Ca21chrR 2199676 2200071 + orf19.7608 2199676 2200071 1 2199676 2200071 2199676 2200071 IPF650.1|Contig4-3108_0053|orf6.8956|CA6007|CaO19.7608|IPF650 Predicted ORF in Assemblies 19, 20 and 21; fluconazole-downregulated; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 2201515 2203001 - ntar_1407 2201515 2203001 1 2203001 2201515 2202356 2202123 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2201728 2202102 + orf19.7609 2201728 2202102 1 2201728 2202102 2201728 2202102 PGA11 IPF647.1|Contig4-3108_0054|Contig4-3108_0055|orf6.8957|CA6008|CaO19.7609|IPF647 Putative GPI-anchored protein of unknown function; possibly spurious ORF (Annotation Working Group prediction) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 2206364 2209965 + orf19.7610 2206364 2209965 1 2206364 2209965 2206947 2209715 PTP3 IPF643.2|Contig4-3108_0065|Contig4-3108_0066|orf6.8958|CA6009|CaO19.7610|IPF643 Protein not essential for viability; similar to S. cerevisiae Ptp3p, which is a protein tyrosine phosphatase; hyphal induced; alkaline upregulated; regulated by Efg1p, Ras1p, cAMP pathways [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2210136 2210738 - orf19.7611 2210136 2210738 1 2210738 2210136 2210638 2210327 TRX1 IPF640.1|Contig4-3108_0068|orf6.8959|CA6010|CaO19.7611 Similar to thioredoxin; biofilm, benomyl, flucytosine, peroxide induced; amphotericin B, caspofungin repressed; upregulated in the presence of human neutrophils; macrophage-downregulated gene [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2211556 2213874 - orf19.7612 2211556 2213874 1 2213874 2211556 2213688 2211628 CTM1 IPF639.1|Contig4-3108_0071|orf6.8960|CA6011|CaO19.7612 Predicted ORF in Assemblies 19, 20 and 21; regulated by Gcn2p and Gcn4p; transcriptionally activated by Mnl1p under weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2214165 2215601 + orf19.7613 2214165 2215601 1 2214165 2215601 2214260 2215117 HCR1 IPF638.1|Contig4-3108_0072|orf6.8961|CA6012|CaO19.7613 Putative translation initiation factor; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2215236 2216261 - orf19.7614 2215236 2216261 1 2216261 2215236 2216261 2215236 IPF635|IPF635.1|Contig4-3108_0073|orf6.8962|CA6013|CaO19.7614 [NOT TRANSCRIBED?] Protein not essential for viability [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 2216391 2217348 + orf19.7615 2216391 2217348 1 2216391 2217348 2216559 2217305 IPF634.1|Contig4-3108_0076|orf6.8963|CA6014|TRS31|CaO19.7615 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2217426 2218567 + orf19.7617 2217426 2218567 1 2217426 2218567 2217467 2218099 IPF631.1|Contig4-3108_0079|orf6.8965|CA6015|ARD1|CaO19.7617 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2218012 2219015 - orf19.7618 2218012 2219015 1 2219015 2218012 2218969 2218139 IPF630.1|Contig4-3108_0080|orf6.8966|CA6016|CaO19.7618|IPF630 Predicted ORF in Assemblies 19, 20 and 21; Plc1p-regulated [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2219838 2221914 + orf19.7619 2219838 2221914 1 2219838 2221914 2219901 2221751 IPF629.1|Contig4-3108_0083|Contig4-3108_0084|orf6.8967|CA6017|CaO19.7619|IPF629 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2221797 2222505 - orf19.7620 2221797 2222505 1 2222505 2221797 2222451 2221873 IPF627.1|Contig4-3108_0085|orf6.8968|CA6018|CaO19.7620|IPF627 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2222978 2225782 + orf19.7621 2222978 2225782 1 2222978 2225782 2223004 2225697 IPF625.1|Contig4-3108_0087|orf6.8969|CA6019|ELG1|CaO19.7621|IPF625 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2224888 2225171 - ntar_1408 2224888 2225171 1 2225171 2224888 2225171 2225037 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2225577 2226733 - orf19.7622 2225577 2226733 1 2226733 2225577 2226700 2225714 SPT3 IPF624.1|Contig4-3108_0088|orf6.8970|CA6020|CaO19.7622 Functional homolog of S. cerevisiae Spt3p; required for virulence in mouse systemic infection; homozygous null mutant is hyperfilamentous [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2226893 2227453 + ntar_1422 2226893 2227453 2 2226893|2227162 2226961|2227453 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2227363 2229053 - orf19.7624 2227363 2229053 1 2229053 2227363 2229053 2227458 IPF621.1|Contig4-3108_0091|orf6.8972|CA6021|CaO19.7624|BFR2 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chrR 2229279 2230018 + orf19.7625 2229279 2230018 1 2229279 2230018 2229458 2229856 PGA1 IPF618.1|Contig4-3108_0092|orf6.8973|CA6022|CaO19.7625|KRE102|IPF618 Putative GPI-anchored protein of unknown function; induced during cell wall regeneration [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2230292 2231139 + orf19.7626 2230292 2231139 2 2230292|2230353 2230292|2231139 2230355 2230984 EIF4E IPF616.1|YOL139C|Contig4-3108_0093|orf6.8974|CA6023|CDC33|CaO19.7626 Putative translation initiation factor eIF4E; genes encoding ribosomal subunits, translation factors, and tRNA synthetases are downregulated upon phagocytosis by murine macrophage; intron in 5'-UTR [label_first_exon=CGD label_last_exon=CGDmod orf_changed=true scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2230955 2232074 - orf19.7627 2230955 2232074 1 2232074 2230955 2231921 2231031 IPF615.1|Contig4-3108_0094|orf6.8975|CA6024|CaO19.7627|IPF615 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2232120 2235418 + orf19.7629 2232120 2235418 1 2232120 2235418 2232120 2235386 IPF614.1|Contig4-3108_0097|orf6.8977|CA6025|CaO19.7629|IPF614 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=I scenario_last_exon=I] Ca21chrR 2235024 2236143 - orf19.7631 2235024 2236143 1 2236143 2235024 2236105 2235395 SLD5 IPF610.1|Contig4-3108_0098|orf6.8979|CA6026|CaO19.7631|IPF610 Predicted ORF in Assemblies 19, 20 and 21; cell-cycle regulated periodic mRNA expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2236205 2237814 + orf19.7632 2236205 2237814 1 2236205 2237814 2236271 2237758 IPF609.1|Contig4-3108_0099|orf6.8980|CA6027|CaO19.7632|IPF609 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2237740 2239544 - orf19.7634 2237740 2239544 1 2239544 2237740 2239475 2237781 MCD1 IPF607.1|Contig4-3108_0100|Contig4-3108_0101|orf6.8982|CA6028|CaO19.7634|IPF607 Protein similar to S. cerevisiae Mcd1p; transcription is repressed in response to alpha pheromone in SpiderM medium; cell-cycle regulated periodic mRNA expression [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2240430 2240788 - ntar_1409 2240430 2240788 1 2240788 2240430 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2240884 2242914 + orf19.7635 2240884 2242914 1 2240884 2242914 2240886 2242727 DRS1 IPF603.1|Contig4-3108_0103|orf6.8983|CA6029|CaO19.7635 Predicted ORF in Assemblies 19, 20 and 21; mutation confers hypersensitivity to 5-fluorouracil (5-FU), tubercidin (7-deazaadenosine); transcription is positively regulated by Tbf1p; downregulated during core stress response [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2243399 2243703 - ntar_1410 2243399 2243703 1 2243703 2243399 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2244051 2245737 - orf19.7637 2244051 2245737 1 2245737 2244051 2245358 2244156 YHB4 orf6.8985|YHB1|IPF599.1|YHB3|Contig4-3108_0104|CA6030|CaO19.7637|YHB2 Protein related to flavohemoglobins; not required for wild-type nitric oxide resistance; has predicted globin, FAD-binding, and NAD(P)-binding domains but lacks some conserved residues of flavohemoglobins; no mRNA detected [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2245766 2247172 + orf19.7638 2245766 2247172 1 2245766 2247172 2245865 2247136 PRO1 IPF597.1|Contig4-3108_0106|orf6.8986|CA6031|CaO19.7638 Transcription is regulated by Nrg1p; regulated by Gcn2p and Gcn4p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2247207 2249653 + orf19.7642 2247207 2249653 1 2247207 2249653 2247207 2249612 IPF596.1|Contig4-3108_0109|orf6.8990|CA6032|CaO19.7642|VPS3|IPF596 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2249416 2250641 - orf19.7643 2249416 2250641 1 2250641 2249416 2250641 2249595 IPF592.1|Contig4-3108_0111|orf6.8991|CA6033|COQ2|CaO19.7643 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2250707 2251108 - orf19.7644 2250707 2251108 1 2251108 2250707 2251108 2250707 IPF590.1|Contig4-3108_0113|orf6.8992|CA6034|CaO19.7644|APC11 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2251165 2253178 - orf19.7645 2251165 2253178 1 2253178 2251165 2253169 2251172 IPF589.1|Contig4-3108_0115|orf6.8993|CA6035|BPL|BPL1|CaO19.7645 Biotin protein ligase; catalyzes covalent attachment of biotin to biotin-dependent enzymes including acetyl CoA carboxylase and pyruvate carboxylase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2253226 2254205 + orf19.7646 2253226 2254205 1 2253226 2254205 2253226 2254167 IPF585.1|Contig4-3108_0116|orf6.8994|CA6036|CaO19.7646|IPF585 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2254313 2255780 + orf19.7648 2254313 2255780 1 2254313 2255780 2254323 2255753 IPF582.1|Contig4-3108_0117|orf6.8996|CA6037|CaO19.7648|MTE3|ERC4 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2254361 2255117 - ntar_1411 2254361 2255117 1 2255117 2254361 2254774 2254364 [label_first_exon=novel label_last_exon=novel orf_changed=false scenario_first_exon=B scenario_last_exon=B] Ca21chrR 2255815 2257053 + orf19.7650 2255815 2257053 1 2255815 2257053 2255840 2256991 LTV1 IPF579.1|Contig4-3108_0118|orf6.8998|CA6038|CaO19.7650 Predicted ORF in Assemblies 19, 20 and 21; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2257116 2258377 + orf19.7652 2257116 2258377 1 2257116 2258377 2257300 2258307 CKA1 IPF576.1|Contig4-3108_0119|orf6.9000|CA6039|CaO19.7652 Putative alpha subunit (catalytic subunit) of protein kinase CK2; Cka1p and Cka2p have a common target with respect to fluconazole resistance; synthetically lethal with CKA2; flucytosine induced [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2258786 2259962 + orf19.7654 2258786 2259962 1 2258786 2259962 2258818 2259927 CPR6 IPF574.1|Contig4-3108_0120|orf6.9002|CA6040|CaO19.7654 Predicted ORF in Assemblies 19, 20 and 21; macrophage/pseudohyphal-repressed; heavy metal (cadmium) stress-induced; heterozygous null mutant displays sensitivity to virgineone [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2260490 2265696 + orf19.7655 2260490 2265696 1 2260490 2265696 2260510 2265696 RPO21 IPF572.2|Contig4-3003_0030|Contig4-3108_0124|orf6.9003|CA6041|CaO19.7655 Protein similar to S. cerevisiae Rpo21p, RNA polymerase II; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2265749 2266513 + orf19.7657 2265749 2266513 1 2265749 2266513 2265749 2266495 POP3 IPF4924.1|Contig4-3003_0028|orf6.9005|CA6042|CaO19.7657|IPF4924 Predicted ORF in Assemblies 19, 20 and 21; decreased expression in response to prostaglandins [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2266553 2267634 + orf19.7658 2266553 2267634 1 2266553 2267634 2266570 2267541 RFC4 IPF4926.1|Contig4-3003_0027|orf6.9006|CA6043|CaO19.7658 Predicted ORF in Assemblies 19, 20 and 21; flucytosine induced; periodic mRNA expression, peak at cell-cycle G1/S phase [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2267513 2269147 - orf19.7660 2267513 2269147 1 2269147 2267513 2269109 2267538 IPF4928.1|Contig4-3003_0026|orf6.9008|CA6044|CaO19.7660|SAC2|IPF4928 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2269212 2271211 + orf19.7661 2269212 2271211 1 2269212 2271211 2269233 2271146 HMI1 IPF4929.1|Contig4-3003_0024|orf6.9009|CA6045|CaO19.7661|IPF4929 ATP-dependent 3' - 5' helicase involved in maintenance of mitochondrial DNA; ortholog of S. cerevisiae Hmi1p [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2271072 2272151 - orf19.7662 2271072 2272151 1 2272151 2271072 2272137 2271130 IPF4931.1|Contig4-3003_0022|orf6.9010|CA6046|CaO19.7662|RTT103|IPF4931 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2272209 2273303 + orf19.7663 2272209 2273303 1 2272209 2273303 2272249 2272926 IPF4933.1|Contig4-3003_0020|orf6.9011|CA6047|CaO19.7663|IPF4933 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2272839 2273341 - orf19.7664 2272839 2273341 1 2273341 2272839 2273334 2272930 IPF4934.1|Contig4-3003_0019|orf6.9012|CA6048|CaO19.7664|IPF4934 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2273390 2273903 - orf19.7665 2273390 2273903 1 2273903 2273390 2273812 2273426 IPF4935.1|Contig4-3003_0018|orf6.9013|CA6049|CaO19.7665|IPF4935 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2274235 2276724 - orf19.7667 2274235 2276724 1 2276724 2274235 2276724 2275918 IAH1 IPF4940.1|Contig4-3003_0014|orf6.9015|CA6051|CaO19.7667|IPF4940 Protein similar to S. cerevisiae Iah1p, which is involved in acetate metabolism; mutation confers hypersensitivity to tunicamycin; transposon mutation affects filamentous growth [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=D scenario_last_exon=D] Ca21chrR 2274335 2275906 + orf19.7666 2274335 2275906 1 2274335 2275906 2274335 2275906 IPF4939.1|Contig4-3003_0016|orf6.9014|CA6050|SEO13|CaO19.7666|IPF4939 Predicted membrane transporter, member of the anion:cation symporter (ACS) family, major facilitator superfamily (MFS) [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] Ca21chrR 2276786 2278691 + orf19.7668 2276786 2278691 1 2276786 2278691 2276897 2278609 MAL2 IPF4942.1|Contig4-3003_0013|orf6.9016|CA6052|CaO19.7668|IPF4942 Alpha-glucosidase that hydrolyzes sucrose; required for sucrose utilization; transcriptionally regulated by Suc1p; expression induced by maltose, repressed by glucose; transposon mutation affects filamentous growth; upregulated in RHE model [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2278509 2281392 - orf19.7670 2278509 2281392 1 2281392 2278509 2281388 2278617 IPF4949.1|Contig4-3003_0011|orf6.9018|CA6053|CaO19.7670|IPF4949 Putative Ca2+/H+ antiporter; fungal-specific (no human or murine homolog) [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2281476 2282486 - orf19.7672 2281476 2282486 1 2282486 2281476 2282476 2281481 IPF4952.1|Contig4-3003_0009|orf6.9020|CA6054|CaO19.7672|IPF4952 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2282547 2282964 + orf19.7673 2282547 2282964 1 2282547 2282964 2282567 2282917 IPF4953.1|Contig4-3003_0006|orf6.9021|CA6055|SMD1|CaO19.7673 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=A scenario_last_exon=A] Ca21chrR 2282904 2283435 - orf19.7675 2282904 2283435 1 2283435 2282904 2283424 2282948 IPF4955.1|Contig4-3003_0003|Contig4-3003_0004|orf6.9023|CA6056|MRPL25|CaO19.7675|IPF4955 ORF Predicted by Annotation Working Group [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2283472 2284673 - orf19.7676 2283472 2284673 1 2284673 2283472 2284606 2283524 XYL2 IPF4959.1|Contig4-3003_0002|orf6.9024|CA6057|CaO19.7676|IPF4959 Protein described as similar to D-xylulose reductase; immunogenic in mouse; soluble protein in hyphae; Hog1p-induced; induced during cell wall regeneration; caspofungin or fluconazole-induced; Mnl1p-induced in weak acid stress [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2284855 2285394 - orf19.7678 2284855 2285394 1 2285394 2284855 2285380 2284895 IPF4961.2|Contig4-3003_0001|orf6.9026|CA6058|ATP16|CaO19.7678 Predicted ORF in Assemblies 19, 20 and 21 [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] Ca21chrR 2285440 2286350 - orf19.7680 2285440 2286350 1 2286350 2285440 2286350 2285529 CTA26 IPF20034.1|Contig4-1945_0001|orf6.9028|CA6059|TLO2|CTA215|CaO19.7680 Putative transcriptional activator; downregulated by Efg1p; transcription is upregulated in an RHE model of oral candidiasis; member of a family of telomere-proximal genes [label_first_exon=CGDmod label_last_exon=CGDmod orf_changed=false scenario_first_exon=F scenario_last_exon=F] CaMTLalpha 372 991 - mtlalpha2 372 991 2 991|447 507|372 991 372 MTLALPHA2 ALPHA2|orf19.10708 A1p and Alpha2p together repress white-opaque switching and mating (an opaque-specific process); homeodomain; gene of MTLalpha (Mating Type Like) locus; a/alpha mating type may increase virulence, provides competitive advantage [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] CaMTLalpha 1698 2987 + obpalpha 1698 2987 1 1698 2987 1698 2987 OBPALPHA orf19.10709|orf19.10710 Similar to oxysterol binding protein; gene is located within the MTLalpha mating-type-like locus [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] CaMTLalpha 3231 6164 + orf19.10711 3231 6164 1 3231 6164 3231 6164 PIKALPHA PIK1|CaO19.10711 Putative phosphatidylinositol kinase; gene is located within the MTLalpha mating-type-like locus [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] CaMTLalpha 6376 6957 + orf19.10712 6376 6957 1 6376 6957 6376 6957 MTLALPHA1 ALPHA1|MTLalpha1|CaO19.10712 Master regulator (activator) of alpha mating type; gene of the MTLalpha (Mating Type Like) locus; ortholog of S. cerevisiae Alpha1p; a/alpha mating type may increase virulence, offers competitive advantage [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z] CaMTLalpha 6992 8668 - orf19.10713 6992 8668 1 8668 6992 8668 6992 PAPALPHA PAP1|CaO19.10713 Putative poly(A) polymerase; PAP is inhibited by parnafungin antifungals; gene is located within the MTLalpha mating-type-like locus [label_first_exon=CGD label_last_exon=CGD orf_changed=false scenario_first_exon=Z scenario_last_exon=Z]