Differentially-dimensioned furrow formation by zygotic gene expression and the MBT
Fig 4
Regulation of furrow dynamics by X chromosome zygotic loci.
(A) The major Drosophila chromosomes, with the telocentric X chromosome indicated in red. (B) Schematic depicting segregation of compound chromosomes generating X aneuploidy. (C) Aneuploid X chromosome embryo measurements of intact furrow depths (black curve) or deepest extent of fragmented furrows (blue curve) (n = 3). (D) nullo Df embryo measurements of intact furrow depths (black curve) or deepest extent of fragmented furrows (blue curve) (n = 3). (E) Disrupted furrow phenotype in aneuploid X and nullo Df embryos during cycle 13 and slow phase of cycle 14. A region just adjacent to the furrow tips is shown. Scale bar = 5 μm (F) Maximal furrow length in WT, aneuploid X and nullo Df during cycles 11–13 (n≥3). *:p<0.05; **: p<0.005; ***: p<0.0005; ns: not significant. (G) Maximal furrow ingression rate of WT, aneuploid X and nullo Df during cycles 11–13 (n≥3). *:p<0.05; ***: p<0.0005; ns: not significant.