Pervasive antagonistic interactions among hybrid incompatibility loci
Fig 3
Possible DMI architecture inferred from observed epistasis in DILs.
Synergistic epistasis (orange boxes), regardless of fitness of the parents, implies a higher-order DMI that involves hab alleles in both introgressions (a, b; green background) and at least one lyc locus at an unknown genomic location (C, dashed circles). Antagonistic interactions (blue boxes) between sterile and non-sterile ILs indicate a pairwise DMI (either a,B in the upper right or A,b in the lower left). Interactions, in any direction, between two sterile ILs suggests a higher-order DMI or complex epistasis between two DMIs (lower right panels).