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Beyond the MHC: A canine model of dermatomyositis shows a complex pattern of genetic risk involving novel loci

Fig 3

Three-locus genotype disease probabilities and frequencies (132 cases, 390 controls).

Word clouds of three-locus genotypes illustrate frequency differences between (A) controls and (B) cases with high-risk genotypes in red, moderate-risk in yellow, and low-risk in blue. Probability of disease (y-axis) for all combinations of PAN2 (x-axis) and MAP3K7CL genotypes are plotted in dogs (C) homozygous and (D) heterozygous for DLA-DRB1*002:01.

Fig 3

doi: https://doi.org/10.1371/journal.pgen.1006604.g003