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Meta-GWAS Accuracy and Power (MetaGAP) Calculator Shows that Hiding Heritability Is Partially Due to Imperfect Genetic Correlations across Studies

Fig 5

Theoretical predictions of power per causal SNP, for total sample size (x-axis) and CGR between two sets of studies (y-axis).

Factor levels: 2 sets of 50 studies, CGR equal to 1 within both sets, 100k independent SNPs, and arising from a subset of 1k independent SNPs.

Fig 5

doi: https://doi.org/10.1371/journal.pgen.1006495.g005