CDC-42 Orients Cell Migration during Epithelial Intercalation in the Caenorhabditis elegans Epidermis
Fig 6
Genetic interaction between cdc-42 and vab-1/EphR.
A) Frequency of dorsal intercalation defects in cdc-42(DN);smg-1(cc546ts), cdc-42(DN); vab-1(e2); smg-1(cc546ts), and vab-1(e2); smg-1(cc546ts) at indicated temperatures (** denotes p≤0.006, Fisher’s Exact Test). Intercalation defects include ipsilateral comigration and medial delay. Statistical analysis performed with expected values from the additive frequencies of cdc-42(DN) 20°C and vab-1(e2) was also significantly different than the double loss of function (p<0.04, Fisher’s Exact Test). Gray numbers indicate number of embryos analyzed per genotype.