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The Adaptive Significance of Natural Genetic Variation in the DNA Damage Response of Drosophila melanogaster

Fig 3

Integrating population genetic and transcriptome data into DNA damage response pathways.

General pathways (bold black) and gene components (italic) and their human orthologs (in brackets) showing significant differentiation between high and low latitudes. Genes that carry at least one differentiated non-synonymous polymorphism (FDR 0.001) are shown in black; genes with early embryo differential expression between high and low latitudes in blue; genes that carried at least one differentiated nsSNP and were differentially expressed in green.

Fig 3

doi: https://doi.org/10.1371/journal.pgen.1005869.g003