< Back to Article
Accounting for Population Structure in Gene-by-Environment Interactions in Genome-Wide Association Studies Using Mixed Models
Fig 3
A correlation between the variance of phenotype explained by the GxE kinship matrix (
) and the inflation factor on GEI statistics (λGC) for human eQTL GxE GWAS data.
The correlation is plotted for the three methods; OLS (A), One RE (B), and Two RE (C). Each dot is each probe, and x-axis is 
and y-axis is λGC. We estimate 
using the GCTA software, and only probes with 
are shown in the plots. The red line is a regression line between λGC and 
, and Pearson correlation coefficient is indicated on the top right of the plot.
doi: https://doi.org/10.1371/journal.pgen.1005849.g003