Reprogramming LCLs to iPSCs Results in Recovery of Donor-Specific Gene Expression Signature
Fig 2
iPSC generation and validation.
A. Representative embryoid body staining for iPSC line 5–2 demonstrating differentiation potential for endoderm, mesoderm, and ectoderm lineages. See S1 Fig for results from all lines. Scale bars represent 200 μm B. Results from qPCR for three endogenous pluripotency-related transcription factors, normalized to GAPDH. iPSC 5–1 was randomly chosen as a reference sample.