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VIB1, a Link between Glucose Signaling and Carbon Catabolite Repression, Is Essential for Plant Cell Wall Degradation by Neurospora crassa

Figure 5

Comparative analysis of gene expression between Δvib-1 and WT shifted to media lacking a carbon source (Nc) versus Avicel (Av) revealed potential CCR regulators.

Hierarchical clustering of FPKM for 770 genes that were differentially expressed in the Δvib-1 mutant when shifted to either carbon-free and Avicel conditions. Heat maps showing log (FPKM) from minimum (bright blue∶L) to maximum (bright yellow∶H) revealed three gene sets: A 273-gene set that has a similar expression pattern between the Δvib-1 mutant and WT, although the induction level on Avicel differed; a 173-gene set that displayed a similar expression pattern between the Δvib-1 mutant and WT that is high (H) on Nc and low (L) on Avicel; a 360-gene set consisting of genes that were generally expressed at higher levels in Δvib-1 on Avicel than in other samples/conditions.

Figure 5

doi: https://doi.org/10.1371/journal.pgen.1004500.g005