Gene Expansion Shapes Genome Architecture in the Human Pathogen Lichtheimia corymbifera: An Evolutionary Genomics Analysis in the Ancient Terrestrial Mucorales (Mucoromycotina)
Gene duplication and duplication of genomic regions within mucoralean genomes in comparison to the genome of A. fumigatus, which (i) inhabits the same natural habitats and (ii) causes similar symptomatology in human like L. corymbifera and (iii) serves as model organism for causative agents of invasive mycoses , .
The genome of A. fumigatus serves as measure for low incidences of singular and segmental gene duplications , . (A) Comparison of gene families between L. corymbifera, R. oryzae and non-mucoralean fungi. Gene families are based on GhostFam homology families. Values for L. corymbifera and R. oryzae are excluded from the “mean fungi” value. (B) Regions with a minimum of 3 genes were tested for multiple occurrences within the genomes by GECKO2.