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Chromatin Landscapes of Retroviral and Transposon Integration Profiles

Figure 2

Influence of gene expression on integration bias.

For each of the systems SB, PB, and MMTV, the unselected integrations are divided into genic integrations, integrations occurring within 1(TSS_upstream), and integrations occurring within 1 kb downstream of the TSS (TSS_downstream). Genes are divided into 5 groups, based on expression level. The sizes of these groups are indicated on the -axis. For each pair of gene expression level and system, the number of observed integrations is counted, and compared to the number of expected integrations.

Figure 2

doi: https://doi.org/10.1371/journal.pgen.1004250.g002