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The Functional Consequences of Variation in Transcription Factor Binding

Figure 6

Magnitude and direction of differential expression after knockdown.

(a) Density plot of all Log2(fold-changes) between the knockdown arrays and controls for genes that are differentially expressed at 5% FDR in one of the knockdown experiments as well as bound by the targeted transcription factor. (b) Plot of the fraction of differentially expressed putative direct targets that were up-regulated in each of the knockdown experiments.

Figure 6