Genomic Confirmation of Hybridisation and Recent Inbreeding in a Vector-Isolated Leishmania Population
Figure 2
Phased haplotypes help identify one of the parental strains.
(A) A heterozygous SNP-dense region of chromosomes 22 (boxed) was one of 86 regions that could be successfully phased to infer haplotypes of at least 5 kb in at least one CUK strain. This region could be phased in 9 strains. (B) Phylogenetic analysis of this region confirms that the two haplotypes have different evolutionary histories: one related to L. infantum JPCM5 and the other distantly related to the two L. donovani reference genomes.