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A Comprehensive tRNA Deletion Library Unravels the Genetic Architecture of the tRNA Pool

Figure 2

Screening the tRNA deletion library across various growth conditions.

(A) Percent of strains exhibiting a growth yield phenotype in various conditions. The color indicates the type of phenotype: impaired (blue) or improved (red). (B) Percent of strains exhibiting a growth rate phenotype in various conditions. (C–D) The σ values measured for both the growth yield (C) and the growth rate (D) for all deletion strains across six conditions. The color bar indicates the σ values, red denoting improvement and blue impairment. Each row denotes a tRNA deletion strain and each column denotes different growth condition. Strains are ordered on the y-axis according to amino acids (denoted by letter) and further separated into families (denoted by lines within the amino-acid box). Black rows denote lethal strains. Gray rows indicate strains for which the respective value was not measured.

Figure 2

doi: https://doi.org/10.1371/journal.pgen.1004084.g002