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Cell-Type Specific Features of Circular RNA Expression

Figure 3

Northern blot shows the dominant isoform of CAMSAP1 is circular.

Northern blot on total HeLa RNA probed for exons 2 and 3 reveals three distinct bands: the largest, the canonical linear isoform of CAMSAP1 (∼7800 nt), a 1446 nt representing a circular isoform of CAMSAP1 containing exon 2, exon 3 and the intervening intron; a 425 nt band representing the fully spliced circular isoform of CAMSAP1 consisting of exons 2 and 3.

Figure 3

doi: https://doi.org/10.1371/journal.pgen.1003777.g003