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From Mouse to Human: Evolutionary Genomics Analysis of Human Orthologs of Essential Genes

Figure 4

Analysis of enrichment of essential genes among genes with de novo mutations in ASD families from four recent studies.

Gene-length and GC content adjusted odds ratios (OR) and P-values for enrichment in EG in either (A) ASD affected probands or (B) family-based controls (i.e. unaffected siblings) are shown.

Figure 4

doi: https://doi.org/10.1371/journal.pgen.1003484.g004