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Sex-Differential Selection and the Evolution of X Inactivation Strategies

Figure 2

Criteria for the evolution of RXI.

Black curves are based on eq. (3) for the mutation-selection balance model of genetic variation (in which case, the x-axis refers to the female selection coefficient, sf). The gray curve is based on eq. (4) for sexually antagonistic alleles maintained by balancing selection (here, the x-axis refers to the male selection coefficient: tm). The area above each curve represents parameter space where unbiased RXI is not favored over PXI. RXI is favored under the complementary parameter space below each curve.

Figure 2

doi: https://doi.org/10.1371/journal.pgen.1003440.g002