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Ubiquitous Polygenicity of Human Complex Traits: Genome-Wide Analysis of 49 Traits in Koreans

Figure 2

Proportion of variance attributed to each chromosome averaged across 47 traits against chromosome length.

In panel A), shown on the y-axis is the averaged estimate of variance explained by each chromosome () across all the traits, except INS0 and HOMA, for which the estimates of variance explained by all SNPs () are zero. In panel B), the estimate of is weighted by for each trait, i.e. , and the length of each chromosome is divided by the total length of the genome, where the intercept (0.008, SE = 0.007) is not significantly different from zero (P = 0.289) and the slope (0.875, SE = 0.150) is not significantly different from 1, which is not significantly different from 1 (P = 0.413).

Figure 2

doi: https://doi.org/10.1371/journal.pgen.1003355.g002