Delineating a Conserved Genetic Cassette Promoting Outgrowth of Body Appendages
Figure 5
GT gene expression analyses on UE-β-Cat-LOF embryos with forced Fgf8 expression.
(A–L) Whole mount in situ analyses using probes indicated. Note that the LOF mutants lack cloacal endoderm/UE Fgf8 (B) and Shh (H) expression, and PCM Bmp4 (E) expression; whereas weak Fgf8 expression (C), partially restored PCM Bmp4 (F) expression, and UE Shh (I) expression can be detected in the LOF mutants with R26Fgf8 allele. Also note the lack of Sp8 expression in LOF mutants with (L) or without (K) R26Fgf8 allele.