Telomerase-Null Survivor Screening Identifies Novel Telomere Recombination Regulators
Figure 2
The effect of the Ino80 complex on survivor formation.
(A) Fifty independent survivor colonies of the ino80Δ tlc1Δ mutant, which was generated from INO80/ino80Δ TLC1/tlc1Δ diploid mutant, were randomly picked and their genomic DNA was isolated for Southern blot assay using a TG1–3 probe. The black triangles indicate Type I survivors. (B) Chart of Type II survivor frequencies in the mutants of Ino80 complex subunits. ND: not done (see Table 1).