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Rbfox1 Downregulation and Altered Calpain 3 Splicing by FRG1 in a Mouse Model of Facioscapulohumeral Muscular Dystrophy (FSHD)

Figure 4

RNA map of Rbfox motifs downstream of exons.

Each point represents the average frequency of UGCAUG in the 150 bp downstream of the 260 exons whose inclusion increases (blue triangles), the 273 exons whose inclusion decreases (red squares) or the 821 expressed alternative cassette exons whose splicing did not change in the comparison (gray circles, q>0.2 and |Sepscore|<0.3). Error bars indicate 95% confidence intervals of the mean frequency distribution for this population of background exons.

Figure 4

doi: https://doi.org/10.1371/journal.pgen.1003186.g004