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Rbfox1 Downregulation and Altered Calpain 3 Splicing by FRG1 in a Mouse Model of Facioscapulohumeral Muscular Dystrophy (FSHD)

Figure 1

Gene expression changes in muscles of mice over-expressing FRG1.

Average linkage clustering was applied to the fold change values of the 440 genes whose expression changes by at least 2 fold (SAM q<0.5) in at least one of the four comparison datasets. Selected nodes are expanded on the right. Genes with increased expression in FRG1 over-expressing muscles are shown in yellow in the heatmap, while those whose expression decreased are in blue.

Figure 1

doi: https://doi.org/10.1371/journal.pgen.1003186.g001