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The Non-Flagellar Type III Secretion System Evolved from the Bacterial Flagellum and Diversified into Host-Cell Adapted Systems

Figure 2

Discrimination between NF-T3SSs and flagella based on Hmmer profile scores.

Each T3SS core protein was scored using the protein profiles for flagella (Y axis) and for NF-T3SSs (X axis). One sees a clear separation around the main diagonal. The color indicates the system (blue for flagellar proteins, red for NF-T3SS proteins). A circle indicates a correct prediction, and a triangle a wrong prediction. The analysis is described in Materials and Methods, and the learning dataset is shown in Figure S1.

Figure 2

doi: https://doi.org/10.1371/journal.pgen.1002983.g002